Kazunori Kataoka

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Matsumoto Akira; Sato Naoko; Kataoka Kazunori; Miyahara Yuji
Noninvasive sialic acid detection at cell membrane by using phenylboronic acid modified self-assembled monolayer gold electrode.
Han Muri; Oba Makoto; Nishiyama Nobuhiro; Kano Mitsunobu R; Kizaka-Kondoh Shinae; Kataoka Kazunori
Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles.
Bae Younsoo; Kataoka Kazunori
Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymers.

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All Publications

2009: Matsumoto Akira; Sato Naoko; Kataoka Kazunori; Miyahara Yuji
Noninvasive sialic acid detection at cell membrane by using phenylboronic acid modified self-assembled monolayer gold electrode.
Journal of the American Chemical Society 2009;131(34):12022-3.
2009: Han Muri; Oba Makoto; Nishiyama Nobuhiro; Kano Mitsunobu R; Kizaka-Kondoh Shinae; Kataoka Kazunori
Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(8):1404-10.
2009: Bae Younsoo; Kataoka Kazunori
Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymers.
Advanced drug delivery reviews 2009;61(10):768-84.
2009: Matsumoto Yu; Itaka Keiji; Yamasoba Tatsuya; Kataoka Kazunori
Intranuclear fluorescence resonance energy transfer analysis of plasmid DNA decondensation from nonviral gene carriers.
The journal of gene medicine 2009;11(7):615-23.
2009: Osada Kensuke; Christie R James; Kataoka Kazunori
Polymeric micelles from poly(ethylene glycol)-poly(amino acid) block copolymer for drug and gene delivery.
Journal of the Royal Society, Interface / the Royal Society 2009;6 Suppl 3():S325-39.
2009: Wang Wenjie; Itaka Keiji; Ohba Shinsuke; Nishiyama Nobuhiro; Chung Ung-il; Yamasaki Yuichi; Kataoka Kazunori
3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells.
Biomaterials 2009;30(14):2705-15.
2009: Nishiyama Nobuhiro; Morimoto Yuji; Jang Woo-Dong; Kataoka Kazunori
Design and development of dendrimer photosensitizer-incorporated polymeric micelles for enhanced photodynamic therapy.
Advanced drug delivery reviews 2009;61(4):327-38.
2009: Nishiyama Nobuhiro; Kataoka Kazunori
[Development of polymeric micelles for the delivery of antitumor agents]
Gan to kagaku ryoho. Cancer & chemotherapy 2009;36(3):357-61.
2009: Dong Wen-Fei; Kishimura Akihiro; Anraku Yasutaka; Chuanoi Sayan; Kataoka Kazunori
Monodispersed polymeric nanocapsules: spontaneous evolution and morphology transition from reducible hetero-PEG PICmicelles by controlled degradation.
Journal of the American Chemical Society 2009;131(11):3804-5.
2009: Itaka Keiji; Kataoka Kazunori
Recent development of nonviral gene delivery systems with virus-like structures and mechanisms.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2009;71(3):475-83.
2009: Nishiyama Nobuhiro; Nakagishi Yoshinori; Morimoto Yuji; Lai Ping-Shan; Miyazaki Kozo; Urano Kyoko; Horie Souta; Kumagai Michiaki; Fukushima Shigeto; Cheng Yu; Jang Woo-Dong; Kikuchi Makoto; Kataoka Kazunori
Enhanced photodynamic cancer treatment by supramolecular nanocarriers charged with dendrimer phthalocyanine.
Journal of controlled release : official journal of the Controlled Release Society 2009;133(3):245-51.
2009: Matsumoto Satoru; Christie R James; Nishiyama Nobuhiro; Miyata Kanjiro; Ishii Atsushi; Oba Makoto; Koyama Hiroyuki; Yamasaki Yuichi; Kataoka Kazunori
Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery.
Biomacromolecules 2009;10(1):119-27.
2009: Kano Mitsunobu R; Komuta Yukari; Iwata Caname; Oka Masako; Shirai Yo-taro; Morishita Yasuyuki; Ouchi Yasuyoshi; Kataoka Kazunori; Miyazono Kohei
Comparison of the effects of the kinase inhibitors imatinib, sorafenib, and transforming growth factor-beta receptor inhibitor on extravasation of nanoparticles from neovasculature.
Cancer science 2009;100(1):173-80.
2009: Oana Hidehiro; Kishimura Akihiro; Yonehara Kei; Yamasaki Yuichi; Washizu Masao; Kataoka Kazunori
Spontaneous formation of giant unilamellar vesicles from microdroplets of a polyion complex by thermally induced phase separation.
Angewandte Chemie (International ed. in English) 2009;48(25):4613-6.
2009: Lee Yan; Ishii Takehiko; Cabral Horacio; Kim Hyun Jin; Seo Ji-Hun; Nishiyama Nobuhiro; Oshima Hiroki; Osada Kensuke; Kataoka Kazunori
Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm.
Angewandte Chemie (International ed. in English) 2009;48(29):5309-12.
2008: Miyata Kanjiro; Oba Makoto; Nakanishi Masataka; Fukushima Shigeto; Yamasaki Yuichi; Koyama Hiroyuki; Nishiyama Nobuhiro; Kataoka Kazunori
Polyplexes from poly(aspartamide) bearing 1,2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity.
Journal of the American Chemical Society 2008;130(48):16287-94.
2008: Miyata Kanjiro; Oba Makoto; Kano Mitsunobu R; Fukushima Shigeto; Vachutinsky Yelena; Han Muri; Koyama Hiroyuki; Miyazono Kohei; Nishiyama Nobuhiro; Kataoka Kazunori
Polyplex micelles from triblock copolymers composed of tandemly aligned segments with biocompatible, endosomal escaping, and DNA-condensing functions for systemic gene delivery to pancreatic tumor tissue.
Pharmaceutical research 2008;25(12):2924-36.
2008: Oba Makoto; Aoyagi Kazuhiro; Miyata Kanjiro; Matsumoto Yu; Itaka Keiji; Nishiyama Nobuhiro; Yamasaki Yuichi; Koyama Hiroyuki; Kataoka Kazunori
Polyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking.
Molecular pharmaceutics 2008;5(6):1080-92.
2008: Wu Shourong; Nishiyama Nobuhiro; Kano Mitsunobu R; Morishita Yasuyuki; Miyazono Kohei; Itaka Keiji; Chung Ung-Il; Kataoka Kazunori
Enhancement of angiogenesis through stabilization of hypoxia-inducible factor-1 by silencing prolyl hydroxylase domain-2 gene.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(7):1227-34.
2008: Takae Seiji; Miyata Kanjiro; Oba Makoto; Ishii Takehiko; Nishiyama Nobuhiro; Itaka Keiji; Yamasaki Yuichi; Koyama Hiroyuki; Kataoka Kazunori
PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors.
Journal of the American Chemical Society 2008;130(18):6001-9.
2008: Sugisaki Kenji; Usui Tomohiko; Nishiyama Nobuhiro; Jang Woo-Dong; Yanagi Yasuo; Yamagami Satoru; Amano Shiro; Kataoka Kazunori
Photodynamic therapy for corneal neovascularization using polymeric micelles encapsulating dendrimer porphyrins.
Investigative ophthalmology & visual science 2008;49(3):894-9.
2008: Wu Shourong; Murai Saomi; Kataoka Kazunori; Miyagishi Makoto
Yin Yang 1 induces transcriptional activity of p73 through cooperation with E2F1.
Biochemical and biophysical research communications 2008;365(1):75-81.
2008: Lee Yan; Miyata Kanjiro; Oba Makoto; Ishii Takehiko; Fukushima Shigeto; Han Muri; Koyama Hiroyuki; Nishiyama Nobuhiro; Kataoka Kazunori
Charge-conversion ternary polyplex with endosome disruption moiety: a technique for efficient and safe gene delivery.
Angewandte Chemie (International ed. in English) 2008;47(28):5163-6.
2007: Masago Kayo; Itaka Keiji; Nishiyama Nobuhiro; Chung Ung-Il; Kataoka Kazunori
Gene delivery with biocompatible cationic polymer: pharmacogenomic analysis on cell bioactivity.
Biomaterials 2007;28(34):5169-75.
2007: Hiki Shigehiro; Kataoka Kazunori
A facile synthesis of azido-terminated heterobifunctional poly(ethylene glycol)s for "click" conjugation.
Bioconjugate chemistry 2007;18(6):2191-6.
2007: Miyata Kanjiro; Fukushima Shigeto; Nishiyama Nobuhiro; Yamasaki Yuichi; Kataoka Kazunori
PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high transfection efficacy.
Journal of controlled release : official journal of the Controlled Release Society 2007;122(3):252-60.
2007: Oba Makoto; Fukushima Shigeto; Kanayama Naoki; Aoyagi Kazuhiro; Nishiyama Nobuhiro; Koyama Hiroyuki; Kataoka Kazunori
Cyclic RGD peptide-conjugated polyplex micelles as a targetable gene delivery system directed to cells possessing alphavbeta3 and alphavbeta5 integrins.
Bioconjugate chemistry 2007;18(5):1415-23.
2007: Xiong May P; Bae Younsoo; Fukushima Shigeto; Forrest M Laird; Nishiyama Nobuhiro; Kataoka Kazunori; Kwon Glen S
pH-responsive Multi-PEGylated dual cationic nanoparticles enable charge modulations for safe gene delivery.
ChemMedChem 2007;2(9):1321-7.
2007: Itaka Keiji; Ohba Shinsuke; Miyata Kanjiro; Kawaguchi Hiroshi; Nakamura Kozo; Takato Tsuyoshi; Chung Ung-Il; Kataoka Kazunori
Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(9):1655-62.
2007: Oishi Motoi; Nagasaki Yukio; Nishiyama Nobuhiro; Itaka Keiji; Takagi Motoki; Shimamoto Akira; Furuichi Yasuhiro; Kataoka Kazunori
Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly(ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes.
ChemMedChem 2007;2(9):1290-7.
2007: Cabral Horacio; Nishiyama Nobuhiro; Kataoka Kazunori
Optimization of (1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity.
Journal of controlled release : official journal of the Controlled Release Society 2007;121(3):146-55.
2007: Han Muri; Bae Younsoo; Nishiyama Nobuhiro; Miyata Kanjiro; Oba Makoto; Kataoka Kazunori
Transfection study using multicellular tumor spheroids for screening non-viral polymeric gene vectors with low cytotoxicity and high transfection efficiencies.
Journal of controlled release : official journal of the Controlled Release Society 2007;121(1-2):38-48.
2007: Takae Seiji; Akiyama Yoshitsugu; Yamasaki Yuichi; Nagasaki Yukio; Kataoka Kazunori
Colloidal Au replacement assay for highly sensitive quantification of low molecular weight analytes by surface plasmon resonance.
Bioconjugate chemistry 2007;18(4):1241-5.
2007: Bae Younsoo; Nishiyama Nobuhiro; Kataoka Kazunori
In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments.
Bioconjugate chemistry 2007;18(4):1131-9.
2007: Akagi D; Oba M; Koyama H; Nishiyama N; Fukushima S; Miyata T; Nagawa H; Kataoka K
Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation.
Gene therapy 2007;14(13):1029-38.
2007: Lee Yan; Fukushima Shigeto; Bae Younsoo; Hiki Shigehiro; Ishii Takehiko; Kataoka Kazunori
A protein nanocarrier from charge-conversion polymer in response to endosomal pH.
Journal of the American Chemical Society 2007;129(17):5362-3.
2007: Kumagai Michiaki; Imai Yutaka; Nakamura Teisaku; Yamasaki Yuichi; Sekino Masaki; Ueno Shoogo; Hanaoka Kenjiro; Kikuchi Kazuya; Nagano Tetsuo; Kaneko Eiji; Shimokado Kentaro; Kataoka Kazunori
Iron hydroxide nanoparticles coated with poly(ethylene glycol)-poly(aspartic acid) block copolymer as novel magnetic resonance contrast agents for in vivo cancer imaging.
Colloids and surfaces. B, Biointerfaces 2007;56(1-2):174-81.
2007: Kano Mitsunobu R; Bae Younsoo; Iwata Caname; Morishita Yasuyuki; Yashiro Masakazu; Oka Masako; Fujii Tomoko; Komuro Akiyoshi; Kiyono Kunihiko; Kaminishi Michio; Hirakawa Kosei; Ouchi Yasuyoshi; Nishiyama Nobuhiro; Kataoka Kazunori; Miyazono Kohei
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3460-5.
2007: Park Joon-Sik; Akiyama Yoshitsugu; Yamasaki Yuichi; Kataoka Kazunori
Preparation and characterization of polyion complex micelles with a novel thermosensitive poly(2-isopropyl-2-oxazoline) shell via the complexation of oppositely charged block ionomers.
Langmuir : the ACS journal of surfaces and colloids 2007;23(1):138-46.
2007: Wu Shourong; Murai Saomi; Kataoka Kazunori; Miyagishi Makoto
Cooperative regulation of p73 promoter by Yin Yang 1 and E2F1.
Nucleic acids symposium series (2004) 2007;(51):347-8.
2007: Kishimura Akihiro; Koide Aya; Osada Kensuke; Yamasaki Yuichi; Kataoka Kazunori
Encapsulation of myoglobin in PEGylated polyion complex vesicles made from a pair of oppositely charged block ionomers: a physiologically available oxygen carrier.
Angewandte Chemie (International ed. in English) 2007;46(32):6085-8.
2006: Nishiyama Nobuhiro; Kataoka Kazunori
Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery.
Pharmacology & therapeutics 2006;112(3):630-48.
2006: Arnida A; Nishiyama N; Jang W-D; Yamasaki Y; Kataoka K
Novel ternary polyplex of triblock copolymer, pDNA and anionic dendrimer phthalocyanine for photochemical enhancement of transgene expression.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):e75-7.
2006: Bae Y; Kataoka K
Significant enhancement of antitumor activity and bioavailability of intracellular pH-sensitive polymeric micelles by folate conjugation.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):e49-50.
2006: Arnida; Nishiyama Nobuhiro; Kanayama Naoki; Jang Woo-Dong; Yamasaki Yuichi; Kataoka Kazunori
PEGylated gene nanocarriers based on block catiomers bearing ethylenediamine repeating units directed to remarkable enhancement of photochemical transfection.
Journal of controlled release : official journal of the Controlled Release Society 2006;115(2):208-15.
2006: Bae Younsoo; Kataoka Kazunori
[Drug and gene delivery with nanotechnology]
Seikagaku. The Journal of Japanese Biochemical Society 2006;78(9):882-7.
2006: Nishiyama Nobuhiro; Arnida; Jang Woo-Dong; Date Kotoe; Miyata Kanjiro; Kataoka Kazunori
Photochemical enhancement of transgene expression by polymeric micelles incorporating plasmid DNA and dendrimer-based photosensitizer.
Journal of drug targeting 2006;14(6):413-24.
2006: Kim Wankee; Yamasaki Yuichi; Kataoka Kazunori
Development of a fitting model suitable for the isothermal titration calorimetric curve of DNA with cationic ligands.
The journal of physical chemistry. B 2006;110(22):10919-25.
2006: Jang Woo-Dong; Nakagishi Yoshinori; Nishiyama Nobuhiro; Kawauchi Satoko; Morimoto Yuji; Kikuchi Makoto; Kataoka Kazunori
Polyion complex micelles for photodynamic therapy: incorporation of dendritic photosensitizer excitable at long wavelength relevant to improved tissue-penetrating property.
Journal of controlled release : official journal of the Controlled Release Society 2006;113(1):73-9.
2006: Oishi Motoi; Kataoka Kazunori; Nagasaki Yukio
pH-responsive three-layered PEGylated polyplex micelle based on a lactosylated ABC triblock copolymer as a targetable and endosome-disruptive nonviral gene vector.
Bioconjugate chemistry 2006;17(3):677-88.
2006: Koide Aya; Kishimura Akihiro; Osada Kensuke; Jang Woo-Dong; Yamasaki Yuichi; Kataoka Kazunori
Semipermeable polymer vesicle (PICsome) self-assembled in aqueous medium from a pair of oppositely charged block copolymers: physiologically stable micro-/nanocontainers of water-soluble macromolecules.
Journal of the American Chemical Society 2006;128(18):5988-9.
2006: Kanayama Naoki; Fukushima Shigeto; Nishiyama Nobuhiro; Itaka Keiji; Jang Woo-Dong; Miyata Kanjiro; Yamasaki Yuichi; Chung Ung-il; Kataoka Kazunori
A PEG-based biocompatible block catiomer with high buffering capacity for the construction of polyplex micelles showing efficient gene transfer toward primary cells.
ChemMedChem 2006;1(4):439-44.
2006: Ueno Shoogo; Ando Joji; Fujita Hiroyuki; Sugawara Tadashi; Jimbo Yasuhiko; Itaka Keiji; Kataoka Kazunori; Ushida Takashi
The state of the art of nanobioscience in Japan.
IEEE transactions on nanobioscience 2006;5(1):54-65.
2006: Itaka Keiji; Chung Ung-Il; Kataoka Kazunori
[Supramolecular nanocarrier for gene and siRNA delivery]
Nippon rinsho. Japanese journal of clinical medicine 2006;64(2):253-7.
2006: Nishiyama Nobuhiro; Kataoka Kazunori
[Nano-engineering for biomedical applications]
Nippon rinsho. Japanese journal of clinical medicine 2006;64(2):199-205.
2005: Ideta Ryuichi; Tasaka Fumitaka; Jang Woo-Dong; Nishiyama Nobuhiro; Zhang Guo-Dong; Harada Atsushi; Yanagi Yasuo; Tamaki Yasuhiro; Aida Takuzo; Kataoka Kazunori
Nanotechnology-based photodynamic therapy for neovascular disease using a supramolecular nanocarrier loaded with a dendritic photosensitizer.
Nano letters 2005;5(12):2426-31.
2005: Nishiyama Nobuhiro; Iriyama Aya; Jang Woo-Dong; Miyata Kanjiro; Itaka Keiji; Inoue Yuji; Takahashi Hidenori; Yanagi Yasuo; Tamaki Yasuhiro; Koyama Hiroyuki; Kataoka Kazunori
Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer.
Nature materials 2005;4(12):934-41.
2005: Miyata Kanjiro; Kakizawa Yoshinori; Nishiyama Nobuhiro; Yamasaki Yuichi; Watanabe Tsunamasa; Kohara Michinori; Kataoka Kazunori
Freeze-dried formulations for in vivo gene delivery of PEGylated polyplex micelles with disulfide crosslinked cores to the liver.
Journal of controlled release : official journal of the Controlled Release Society 2005;109(1-3):15-23.
2005: Nishiyama Nobuhiro; Kataoka Kazunori
[Medical applications of nanotechnology: polymeric micelles for drug delivery]
Nippon Geka Gakkai zasshi 2005;106(11):700-5.
2005: Usui Tomohiko; Sugisaki Kenji; Amano Shiro; Jang Woo-Dong; Nishiyama Nobuhiro; Kataoka Kazunori
New drug delivery for corneal neovascularization using polyion complex micelles.
Cornea 2005;24(8 Suppl):S39-S42.
2005: Bae Younsoo; Jang Woo-Dong; Nishiyama Nobuhiro; Fukushima Shigeto; Kataoka Kazunori
Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery.
Molecular bioSystems 2005;1(3):242-50.
2005: Oishi Motoi; Hayama Tetsuya; Akiyama Yoshitsugu; Takae Seiji; Harada Atsushi; Yamasaki Yuichi; Nagatsugi Fumi; Sasaki Shigeki; Nagasaki Yukio; Kataoka Kazunori
Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide: polyion complex (PIC) micelles based on poly(ethylene glycol)-SS-oligodeoxynucleotide conjugate.
Biomacromolecules 2005;6(5):2449-54.
2005: Osada Kensuke; Yamasaki Yuichi; Katayose Satoshi; Kataoka Kazunori
A synthetic block copolymer regulates S1 nuclease fragmentation of supercoiled plasmid DNA.
Angewandte Chemie (International ed. in English) 2005;44(23):3544-8.
2005: Oishi Motoi; Nagatsugi Fumi; Sasaki Shigeki; Nagasaki Yukio; Kataoka Kazunori
Smart polyion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotides containing acid-labile linkages.
Chembiochem : a European journal of chemical biology 2005;6(4):718-25.
2005: Yuan Xiaofei; Harada Atsushi; Yamasaki Yuichi; Kataoka Kazunori
Stabilization of lysozyme-incorporated polyion complex micelles by the omega-end derivatization of poly(ethylene glycol)-poly(alpha,beta-aspartic acid) block copolymers with hydrophobic groups.
Langmuir : the ACS journal of surfaces and colloids 2005;21(7):2668-74.
2005: Takae Seiji; Akiyama Yoshitsugu; Otsuka Hidenori; Nakamura Teisaku; Nagasaki Yukio; Kataoka Kazunori
Ligand density effect on biorecognition by PEGylated gold nanoparticles: regulated interaction of RCA120 lectin with lactose installed to the distal end of tethered PEG strands on gold surface.
Biomacromolecules 2005;6(2):818-24.
2005: Fukushima Shigeto; Miyata Kanjiro; Nishiyama Nobuhiro; Kanayama Naoki; Yamasaki Yuichi; Kataoka Kazunori
PEGylated polyplex micelles from triblock catiomers with spatially ordered layering of condensed pDNA and buffering units for enhanced intracellular gene delivery.
Journal of the American Chemical Society 2005;127(9):2810-1.
2005: Oishi Motoi; Nagasaki Yukio; Itaka Keiji; Nishiyama Nobuhiro; Kataoka Kazunori
Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells.
Journal of the American Chemical Society 2005;127(6):1624-5.
2005: Bae Younsoo; Nishiyama Nobuhiro; Fukushima Shigeto; Koyama Hiroyuki; Yasuhiro Matsumura; Kataoka Kazunori
Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy.
Bioconjugate chemistry 2005;16(1):122-30.
2005: Jang Woo-Dong; Nishiyama Nobuhiro; Zhang Guo-Dong; Harada Atsushi; Jiang Dong-Lin; Kawauchi Satoko; Morimoto Yuji; Kikuchi Makoto; Koyama Hiroyuki; Aida Takuzo; Kataoka Kazunori
Supramolecular nanocarrier of anionic dendrimer porphyrins with cationic block copolymers modified with polyethylene glycol to enhance intracellular photodynamic efficacy.
Angewandte Chemie (International ed. in English) 2005;44(3):419-23.
2005: Cabral Horacio; Nishiyama Nobuhiro; Okazaki Soichiro; Koyama Hiroyuki; Kataoka Kazunori
Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles.
Journal of controlled release : official journal of the Controlled Release Society 2005;101(1-3):223-32.
2005: Kataoka Kazunori; Itaka Keiji; Nishiyama Nobuhiro; Yamasaki Yuichi; Oishi Motoi; Nagasaki Yukio
Smart polymeric micelles as nanocarriers for oligonucleotides and siRNA delivery.
Nucleic acids symposium series (2004) 2005;(49):17-8.
2004: Otsuka Hidenori; Nagasaki Yukio; Kataoka Kazunori
Characterization of aldehyde-PEG tethered surfaces: influence of PEG chain length on the specific biorecognition.
Langmuir : the ACS journal of surfaces and colloids 2004;20(26):11285-7.
2004: Wakebayashi Daisuke; Nishiyama Nobuhiro; Itaka Keiji; Miyata Kanjiro; Yamasaki Yuichi; Harada Atsushi; Koyama Hiroyuki; Nagasaki Yukio; Kataoka Kazunori
Polyion complex micelles of pDNA with acetal-poly(ethylene glycol)-poly(2-(dimethylamino)ethyl methacrylate) block copolymer as the gene carrier system: physicochemical properties of micelles relevant to gene transfection efficacy.
Biomacromolecules 2004;5(6):2128-36.
2004: Itaka Keiji; Kanayama Naoki; Nishiyama Nobuhiro; Jang Woo-Dong; Yamasaki Yuichi; Nakamura Kozo; Kawaguchi Hiroshi; Kataoka Kazunori
Supramolecular nanocarrier of siRNA from PEG-based block catiomer carrying diamine side chain with distinctive pKa directed to enhance intracellular gene silencing.
Journal of the American Chemical Society 2004;126(42):13612-3.
2004: Jule Eduardo; Yamamoto Yuji; Thouvenin Muriel; Nagasaki Yukio; Kataoka Kazunori
Thermal characterization of poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles based on pyrene excimer formation.
Journal of controlled release : official journal of the Controlled Release Society 2004;97(3):407-19.
2004: Otsuka Hidenori; Hirano Akihiro; Nagasaki Yukio; Okano Teruo; Horiike Yasuhiro; Kataoka Kazunori
Two-dimensional multiarray formation of hepatocyte spheroids on a microfabricated PEG-brush surface.
Chembiochem : a European journal of chemical biology 2004;5(6):850-5.
2004: Matsumoto Akira; Yoshida Ryo; Kataoka Kazunori
Glucose-responsive polymer gel bearing phenylborate derivative as a glucose-sensing moiety operating at the physiological pH.
Biomacromolecules 2004;5(3):1038-45.
2004: Akiyama Yoshitsugu; Nagasaki Yukio; Kataoka Kazunori
Synthesis of heterotelechelic poly(ethylene glycol) derivatives having alpha-benzaldehyde and omega-pyridyl disulfide groups by ring opening polymerization of ethylene oxide using 4-(diethoxymethyl)benzyl alkoxide as a novel initiator.
Bioconjugate chemistry 2004;15(2):424-7.
2004: Jaturanpinyo Montree; Harada Atsushi; Yuan Xiaofei; Kataoka Kazunori
Preparation of bionanoreactor based on core-shell structured polyion complex micelles entrapping trypsin in the core cross-linked with glutaraldehyde.
Bioconjugate chemistry 2004;15(2):344-8.
2004: Wakebayashi Daisuke; Nishiyama Nobuhiro; Yamasaki Yuichi; Itaka Keiji; Kanayama Naoki; Harada Atsushi; Nagasaki Yukio; Kataoka Kazunori
Lactose-conjugated polyion complex micelles incorporating plasmid DNA as a targetable gene vector system: their preparation and gene transfecting efficiency against cultured HepG2 cells.
Journal of controlled release : official journal of the Controlled Release Society 2004;95(3):653-64.
2004: Miyata Kanjiro; Kakizawa Yoshinori; Nishiyama Nobuhiro; Harada Atsushi; Yamasaki Yuichi; Koyama Hiroyuki; Kataoka Kazunori
Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression.
Journal of the American Chemical Society 2004;126(8):2355-61.
2004: Ideta Ryuichi; Yanagi Yasuo; Tamaki Yasuhiro; Tasaka Fumitaka; Harada Atsushi; Kataoka Kazunori
Effective accumulation of polyion complex micelle to experimental choroidal neovascularization in rats.
FEBS letters 2004;557(1-3):21-5.
2004: Itaka Keiji; Harada Atsushi; Yamasaki Yuichi; Nakamura Kozo; Kawaguchi Hiroshi; Kataoka Kazunori
In situ single cell observation by fluorescence resonance energy transfer reveals fast intra-cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine.
The journal of gene medicine 2004;6(1):76-84.
2003: Nishiyama Nobuhiro; Okazaki Souichiro; Cabral Horacio; Miyamoto Masaki; Kato Yukio; Sugiyama Yuichi; Nishio Kazuto; Matsumura Yasuhiro; Kataoka Kazunori
Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice.
Cancer research 2003;63(24):8977-83.
2003: Zhang Guo-Dong; Harada Atsushi; Nishiyama Nobuhiro; Jiang Dong-Lin; Koyama Hiroyuki; Aida Takuzo; Kataoka Kazunori
Polyion complex micelles entrapping cationic dendrimer porphyrin: effective photosensitizer for photodynamic therapy of cancer.
Journal of controlled release : official journal of the Controlled Release Society 2003;93(2):141-50.
2003: Itaka Keiji; Yamauchi Kyosuke; Harada Atsushi; Nakamura Kozo; Kawaguchi Hiroshi; Kataoka Kazunori
Polyion complex micelles from plasmid DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer as serum-tolerable polyplex system: physicochemical properties of micelles relevant to gene transfection efficiency.
Biomaterials 2003;24(24):4495-506.
2003: Bae Younsoo; Fukushima Shigeto; Harada Atsushi; Kataoka Kazunori
Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change.
Angewandte Chemie (International ed. in English) 2003;42(38):4640-3.
2003: Oishi Motoi; Sasaki Shigeki; Nagasaki Yukio; Kataoka Kazunori
pH-responsive oligodeoxynucleotide (ODN)-poly(ethylene glycol) conjugate through acid-labile beta-thiopropionate linkage: preparation and polyion complex micelle formation.
Biomacromolecules 2003;4(5):1426-32.
2003: Matsumoto Akira; Ikeda Syuhei; Harada Atsushi; Kataoka Kazunori
Glucose-responsive polymer bearing a novel phenylborate derivative as a glucose-sensing moiety operating at physiological pH conditions.
Biomacromolecules 2003;4(5):1410-6.
2003: Nishiyama Nobuhiro; Koizumi Fumiaki; Okazaki Soichiro; Matsumura Yasuhiro; Nishio Kazuto; Kataoka Kazunori
Differential gene expression profile between PC-14 cells treated with free cisplatin and cisplatin-incorporated polymeric micelles.
Bioconjugate chemistry 2003;14(2):449-57.
2003: Otsuka Hidenori; Uchimura Eiichiro; Koshino Hiroyuki; Okano Teruo; Kataoka Kazunori
Anomalous binding profile of phenylboronic acid with N-acetylneuraminic acid (Neu5Ac) in aqueous solution with varying pH.
Journal of the American Chemical Society 2003;125(12):3493-502.
2003: Jule Eduardo; Nagasaki Yukio; Kataoka Kazunori
Lactose-installed poly(ethylene glycol)-poly(d,l-lactide) block copolymer micelles exhibit fast-rate binding and high affinity toward a protein bed simulating a cell surface. A surface plasmon resonance study.
Bioconjugate chemistry 2003;14(1):177-86.
2003: Nishiyama Nobuhiro; Stapert Hendrik R; Zhang Guo-Dong; Takasu Daisuke; Jiang Dong-Lin; Nagano Tetsuo; Aida Takuzo; Kataoka Kazunori
Light-harvesting ionic dendrimer porphyrins as new photosensitizers for photodynamic therapy.
Bioconjugate chemistry 2003;14(1):58-66.
2002: Yamamoto Yuji; Yasugi Kenji; Harada Atsushi; Nagasaki Yukio; Kataoka Kazunori
Temperature-related change in the properties relevant to drug delivery of poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles in aqueous milieu.
Journal of controlled release : official journal of the Controlled Release Society 2002;82(2-3):359-71.
2002: Itaka Keiji; Harada Atsushi; Nakamura Kozo; Kawaguchi Hiroshi; Kataoka Kazunori
Evaluation by fluorescence resonance energy transfer of the stability of nonviral gene delivery vectors under physiological conditions.
Biomacromolecules 2002;3(4):841-5.
2002: Kakizawa Yoshinori; Kataoka Kazunori
Block copolymer micelles for delivery of gene and related compounds.
Advanced drug delivery reviews 2002;54(2):203-22.
2001: Yamamoto Y; Nagasaki Y; Kato Y; Sugiyama Y; Kataoka K
Long-circulating poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles with modulated surface charge.
Journal of controlled release : official journal of the Controlled Release Society 2001;77(1-2):27-38.
2001: Otsuka H; Akiyama Y; Nagasaki Y; Kataoka K
Quantitative and reversible lectin-induced association of gold nanoparticles modified with alpha-lactosyl-omega-mercapto-poly(ethylene glycol).
Journal of the American Chemical Society 2001;123(34):8226-30.
2001: Nishiyama N; Kato Y; Sugiyama Y; Kataoka K
Cisplatin-loaded polymer-metal complex micelle with time-modulated decaying property as a novel drug delivery system.
Pharmaceutical research 2001;18(7):1035-41.
2001: Nishiyama N; Kataoka K
Preparation and characterization of size-controlled polymeric micelle containing cis-dichlorodiammineplatinum(II) in the core.
Journal of controlled release : official journal of the Controlled Release Society 2001;74(1-3):83-94.
2001: Harada A; Kataoka K
Pronounced activity of enzymes through the incorporation into the core of polyion complex micelles made from charged block copolymers.
Journal of controlled release : official journal of the Controlled Release Society 2001;72(1-3):85-91.
2001: Harada A; Togawa H; Kataoka K
Physicochemical properties and nuclease resistance of antisense-oligodeoxynucleotides entrapped in the core of polyion complex micelles composed of poly(ethylene glycol)-poly(L-lysine) block copolymers.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2001;13(1):35-42.
2001: Kataoka K; Harada A; Nagasaki Y
Block copolymer micelles for drug delivery: design, characterization and biological significance.
Advanced drug delivery reviews 2001;47(1):113-31.
2001: Uchimura E; Otsuka H; Okano T; Sakurai Y; Kataoka K
Totally synthetic polymer with lectin-like function: induction of killer cells by the copolymer of 3-acrylamidophenylboronic acid with N,N-dimethylacrylamide.
Biotechnology and bioengineering 2001;72(3):307-14.
2001: Nagasaki Y; Yasugi K; Yamamoto Y; Harada A; Kataoka K
Sugar-installed block copolymer micelles: their preparation and specific interaction with lectin molecules.
Biomacromolecules 2001;2(4):1067-70.
2001: Kakizawa Y; Harada A; Kataoka K
Glutathione-sensitive stabilization of block copolymer micelles composed of antisense DNA and thiolated poly(ethylene glycol)-block-poly(L-lysine): a potential carrier for systemic delivery of antisense DNA.
Biomacromolecules 2001;2(2):491-7.
2000: Kataoka K; Matsumoto T; Yokoyama M; Okano T; Sakurai Y; Fukushima S; Okamoto K; Kwon G S
Doxorubicin-loaded poly(ethylene glycol)-poly(beta-benzyl-L-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance.
Journal of controlled release : official journal of the Controlled Release Society 2000;64(1-3):143-53.
2000: Otsuka H; Nagasaki Y; Kataoka K
Surface characterization of functionalized polylactide through the coating with heterobifunctional poly(ethylene glycol)/polylactide block copolymers.
Biomacromolecules 2000;1(1):39-48.
1999: Yasugi K; Nagasaki Y; Kato M; Kataoka K
Preparation and characterization of polymer micelles from poly(ethylene glycol)-poly(D,L-lactide) block copolymers as potential drug carrier.
Journal of controlled release : official journal of the Controlled Release Society 1999;62(1-2):89-100.
1999: Yokoyama M; Okano T; Sakurai Y; Fukushima S; Okamoto K; Kataoka K
Selective delivery of adriamycin to a solid tumor using a polymeric micelle carrier system.
Journal of drug targeting 1999;7(3):171-86.
1998: Yokoyama M; Satoh A; Sakurai Y; Okano T; Matsumura Y; Kakizoe T; Kataoka K
Incorporation of water-insoluble anticancer drug into polymeric micelles and control of their particle size.
Journal of controlled release : official journal of the Controlled Release Society 1998;55(2-3):219-29.
1998: Kataoka K
[Intracellular gene delivery by polymer micelle vectors]
Nippon rinsho. Japanese journal of clinical medicine 1998;56(3):718-23.
1998: Nakamura T; Nagasaki Y; Kataoka K
Synthesis of heterobifunctional poly(ethylene glycol) with a reducing monosaccharide residue at one end.
Bioconjugate chemistry 1998;9(2):300-3.
1998: Katayose S; Kataoka K
Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethylene glycol)-poly(L-lysine) block copolymer.
Journal of pharmaceutical sciences 1998;87(2):160-3.
1998: Yokoyama M; Fukushima S; Uehara R; Okamoto K; Kataoka K; Sakurai Y; Okano T
Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor.
Journal of controlled release : official journal of the Controlled Release Society 1998;50(1-3):79-92.
1998: Kataoka K; Ito H; Amano H; Nagasaki Y; Kato M; Tsuruta T; Suzuki K; Okano T; Sakurai Y
Minimized platelet interaction with poly(2-hydroxyethyl methacrylate-block-4-bis(trimethylsilyl)methylstyrene) hydrogel showing anomalously high free water content.
Journal of biomaterials science. Polymer edition 1998;9(2):111-29.
1997: Katayose S; Kataoka K
Water-soluble polyion complex associates of DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer.
Bioconjugate chemistry 1997;8(5):702-7.
1997: Hisamitsu I; Kataoka K; Okano T; Sakurai Y
Glucose-responsive gel from phenylborate polymer and poly(vinyl alcohol): prompt response at physiological pH through the interaction of borate with amino group in the gel.
Pharmaceutical research 1997;14(3):289-93.
1997: Aoki T; Nagao Y; Sanui K; Ogata N; Kikuchi A; Sakurai Y; Kataoka K; Okano T
Effect of phenylboronic acid groups in copolymers on endothelial cell differentiation into capillary structures.
Journal of biomaterials science. Polymer edition 1997;9(1):1-14.
1996: Kikuchi A; Taira H; Tsuruta T; Hayashi M; Kataoka K
Adsorbed serum protein mediated adhesion and growth behavior of bovine aortic endothelial cells on polyamine graft copolymer surfaces.
Journal of biomaterials science. Polymer edition 1996;8(2):77-90.
1995: Nagasaki Y; Iijima M; Kato M; Kataoka K
Primary amino-terminal heterobifunctional poly(ethylene oxide). Facile synthesis of poly(ethylene oxide) with a primary amino group at one end and a hydroxyl group at the other end.
Bioconjugate chemistry 1995;6(6):702-4.
1995: Nagasaki Y; Kutsuna T; Iijima M; Kato M; Kataoka K; Kitano S; Kadoma Y
Formyl-ended heterobifunctional poly(ethylene oxide): synthesis of poly(ethylene oxide) with a formyl group at one end and a hydroxyl group at the other end.
Bioconjugate chemistry 1995;6(2):231-3.
1995: Cammas S; Nagasaki Y; Kataoka K
Heterobifunctional poly(ethylene oxide): synthesis of alpha-methoxy-omega-amino and alpha-hydroxy-omega-amino PEOs with the same molecular weights.
Bioconjugate chemistry 1995;6(2):226-30.
1995: Aoki T; Nagao Y; Terada E; Sanui K; Ogata N; Yamada N; Sakurai Y; Kataoka K; Okano T
Endothelial cell differentiation into capillary structures by copolymer surfaces with phenylboronic acid groups.
Journal of biomaterials science. Polymer edition 1995;7(7):539-50.
1992: Yokoyama M; Kwon G S; Okano T; Sakurai Y; Seto T; Kataoka K
Preparation of micelle-forming polymer-drug conjugates.
Bioconjugate chemistry 1992;3(4):295-301.
1992: Yokoyama M; Okano T; Sakurai Y; Kikuchi A; Ohsako N; Nagasaki Y; Kataoka K
Synthesis of poly(ethylene oxide) with heterobifunctional reactive groups at its terminals by an anionic initiator.
Bioconjugate chemistry 1992;3(4):275-6.
1992: Kikuchi A; Kataoka K; Tsuruta T
Adhesion and proliferation of bovine aortic endothelial cells on monoamine- and diamine-containing polystyrene derivatives.
Journal of biomaterials science. Polymer edition 1992;3(3):253-60.
1992: Kikuchi A; Kataoka K; Tsuruta T
The role of protonation and conformational transition of polyamine grafts in platelet retention to polyamine-graft-PHEMA copolymer surfaces.
Journal of biomaterials science. Polymer edition 1992;3(5):355-74.
1991: Yokoyama M; Okano T; Sakurai Y; Ekimoto H; Shibazaki C; Kataoka K
Toxicity and antitumor activity against solid tumors of micelle-forming polymeric anticancer drug and its extremely long circulation in blood.
Cancer research 1991;51(12):3229-36.
1990: Yokoyama M; Miyauchi M; Yamada N; Okano T; Sakurai Y; Kataoka K; Inoue S
Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer.
Cancer research 1990;50(6):1693-700.
1989: Maruyama A; Tsuruta T; Kataoka K; Sakurai Y
Separation of B and T lymphocytes by cellular adsorption chromatography with polyamine graft copolymers as column matrices. II. Recovery of adsorbed B cell enriched populations from the column.
Biomaterials 1989;10(6):393-9.
1989: Yui N; Kataoka K; Sakurai Y; Fujishima Y; Aoki T; Maruyama A; Sanui K; Ogata N
Change in cytoplasmic free Ca2+ concentration in rabbit platelets contacting with albumin coated and uncoated polystyrene surfaces.
Biomaterials 1989;10(5):309-12.
1989: Maruyama A; Tsuruta T; Kataoka K; Sakurai Y
Elimination of cellular active adhesion on microdomain-structured surface of graft-polyamine copolymers.
Biomaterials 1989;10(5):291-8.
1989: Nabeshima Y; Tsuruta T; Kataoka K; Sakurai Y
Structural control of poly(2-hydroxyethyl methacrylate)-graft-polyamine copolymers for differential retention of rat lymphocyte subpopulations.
Journal of biomaterials science. Polymer edition 1989;1(2):85-97.
1988: Kataoka K
Molecular design of materials for cell separation.
Artificial organs 1988;12(6):511-3.
1988: Maruyama A; Tsuruta T; Kataoka K; Sakurai Y
Quantitative evaluation of rat lymphocyte adsorption on microdomain structured surfaces of poly(2-hydroxyethyl methacrylate)/polyamine.
Biomaterials 1988;9(6):471-81.
1988: Maruyama A; Tsuruta T; Kataoka K; Sakurai Y
Separation of B- and T-lymphocytes by cellular adsorption chromatography using poly(2-hydroxyethyl methacrylate)/polyamine graft copolymer as column adsorbent.
Journal of biomedical materials research 1988;22(6):555-71.
1988: Yui N; Kataoka K; Sakurai Y; Aoki T; Sanui K; Ogata N
In vitro and in vivo studies on antithrombogenicity of poly(propylene oxide) segmented nylon 610 in relation to its crystalline-amorphous microstructure.
Biomaterials 1988;9(3):225-9.
1988: Kataoka K; Sakurai Y; Hanai T; Maruyama A; Tsuruta T
Immunoaffinity chromatography of lymphocyte subpopulations using tert-amine derived matrices with adsorbed antibodies.
Biomaterials 1988;9(3):218-24.
1986: Yui N; Sanui K; Ogata N; Kataoka K; Okano T; Sakurai Y
Effect of microstructure of poly(propylene-oxide)-segmented polyamides on platelet adhesion.
Journal of biomedical materials research 1986;20(7):929-43.
1985: Yui N; Sanui K; Ogata N; Kataoka K; Okano T; Sakurai Y
Reversibility of granulocyte adhesion using polyamine-grafted nylon-6 as a new column substrate for granulocyte separation.
Biomaterials 1985;6(6):409-15.
1983: Yui N; Sanui K; Ogata N; Kataoka K; Okano T; Sakurai Y
Effect of crystallinity of polyamides on adhesion-separation behavior of granulocytes.
Journal of biomedical materials research 1983;17(2):383-8.

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