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Kazunori Kataoka

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Yoichiro Matsumoto; Kensuke Osada; Takashi Azuma; Kazunori Kataoka; Kiyoshi Yoshinaka; Yiwei Zhang; Shu Takagi
Size effect of complexed plasmid DNA to gene transfection efficiency of microbubble-mediated sonoporation.
Yasutaka Anraku; Akihiro Kishimura; Yuichi Yamasaki; Kazunori Kataoka
Living unimodal growth of polyion complex vesicles via two-dimensional supramolecular polymerization.
Satoshi Uchida; Toru Ogata; Kensuke Osada; Hirokuni Uchida; Shigeto Fukushima; Kentaro Hayakawa; Takehiko Ishii; Keiji Itaka; Kazunori Kataoka
In vivo messenger RNA introduction into the central nervous system using polyplex nanomicelle.

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2013: Yoichiro Matsumoto; Kensuke Osada; Takashi Azuma; Kazunori Kataoka; Kiyoshi Yoshinaka; Yiwei Zhang; Shu Takagi
Size effect of complexed plasmid DNA to gene transfection efficiency of microbubble-mediated sonoporation.
The Journal of the Acoustical Society of America 2013;133(5):3495.
2013: Yasutaka Anraku; Akihiro Kishimura; Yuichi Yamasaki; Kazunori Kataoka
Living unimodal growth of polyion complex vesicles via two-dimensional supramolecular polymerization.
Journal of the American Chemical Society 2013;135(4):1423-9.
2013: Satoshi Uchida; Toru Ogata; Kensuke Osada; Hirokuni Uchida; Shigeto Fukushima; Kentaro Hayakawa; Takehiko Ishii; Keiji Itaka; Kazunori Kataoka
In vivo messenger RNA introduction into the central nervous system using polyplex nanomicelle.
PloS one 2013;8(2):e56220.
2013: Noha Gouda; R James Christie; Shigeto Fukushima; Akihiro Kishimura; Xueying Liu; Kanjiro Miyata; Nobuhiro Nishiyama; Takahiro Nomoto; Tomoya Suma; Kazunori Kataoka
Silica nanogelling of environment-responsive PEGylated polyplexes for enhanced stability and intracellular delivery of siRNA.
Biomaterials 2013;34(2):562-70.
2013: Peng Mi; Nobuhiro Nishiyama; Mohammad Rafi; Tsuneo Saga; Ishii Takehiko; Yasuko Terada; Ichio Aoki; Horacio Cabral; Daisuke Kokuryo; Kazunori Kataoka
Gd-DTPA-loaded polymer-metal complex micelles with high relaxivity for MR cancer imaging.
Biomaterials 2013;34(2):492-500.
2012: Mai Sanjoh; R James Christie; Shigehiro Hiki; Takehiko Ishii; Yoshinori Maeda; Kanjiro Miyata; Nobuhiro Nishiyama; Frederico Pittella; Kazunori Kataoka
Dual environment-responsive polyplex carriers for enhanced intracellular delivery of plasmid DNA.
Biomacromolecules 2012;13(11):3641-9.
2012: Tsz Chung Lai; Kazunori Kataoka; Glen S Kwon
Bioreducible polyether-based pDNA ternary polyplexes: balancing particle stability and transfection efficiency.
Colloids and surfaces. B, Biointerfaces 2012;99():27-37.
2012: Mitsuru Naito; Takehiko Ishii; Akira Matsumoto; Yuji Miyahara; Kanjiro Miyata; Kazunori Kataoka
A phenylboronate-functionalized polyion complex micelle for ATP-triggered release of siRNA.
Angewandte Chemie (International ed. in English) 2012;51(43):10751-5.
2012: Tomoya Suma; Hiroyasu Takemoto; Sumiyo Watanabe; Kanjiro Miyata; Nobuhiro Nishiyama; Momoko Shioyama; Yasutaka Anraku; R James Christie; Noha Gouda; Takehiko Ishii; Kazunori Kataoka
Smart multilayered assembly for biocompatible siRNA delivery featuring dissolvable silica, endosome-disrupting polycation, and detachable PEG.
ACS nano 2012;6(8):6693-705.
2012: Shuhei Murayama; Kohki Okabe; Kensuke Osada; Baowei Su; Takashi Funatsu; Kazunori Kataoka; Akihiro Kishimura; Masayuki Miura; Masaru Kato
NanoPARCEL: a method for controlling cellular behavior with external light.
Chemical communications (Cambridge, England) 2012;48(67):8380-2.
2012: Kensuke Osada; Megumi Yamamoto; Yasutaka Anraku; Horacio Cabral; Akihiro Kishimura; Sangeun Lee; Tetsuya Matsuura; Yuki Mochida; Kazuya Nagata; Nobuhiro Nishiyama; Kazunori Kataoka
Bioactive polymeric metallosomes self-assembled through block copolymer-metal complexation.
Journal of the American Chemical Society 2012;134(32):13172-5.
2012: Hiroyasu Takemoto; Shota Hattori; Takehiko Ishii; Kanjiro Miyata; Nobuhiro Nishiyama; Shigehito Osawa; Kazunori Kataoka
Accelerated polymer-polymer click conjugation by freeze-thaw treatment.
Bioconjugate chemistry 2012;23(8):1503-6.
2012: Frederico Pittella; Tomoya Suma; Sumiyo Watanabe; Qixian Chen; R James Christie; Yoshinori Maeda; Kanjiro Miyata; Nobuhiro Nishiyama; Kensuke Osada; Kazunori Kataoka
Pancreatic cancer therapy by systemic administration of VEGF siRNA contained in calcium phosphate/charge-conversional polymer hybrid nanoparticles.
Journal of controlled release : official journal of the Controlled Release Society 2012;161(3):868-74.
2012: Kozo Miyazaki; Yuji Morimoto; Ken-Ichi Nakatate; Nobuhiro Nishiyama; Nariyoshi Shinomiya; Wei-Zhi Hu; Keiji Kaneda; Yasuhiro Maekawa; Kazunori Kataoka
A novel homogeneous irradiation fiber probe for whole bladder wall photodynamic therapy.
Lasers in surgery and medicine 2012;44(5):413-20.
2012: R James Christie; Shigeto Fukushima; Julien Halnaut; Hyun Jin Kim; Yu Matsumoto; Kanjiro Miyata; Nobuhiro Nishiyama; Takahiro Nomoto; Kensuke Osada; Frederico Pittella; Kazunori Kataoka
Targeted polymeric micelles for siRNA treatment of experimental cancer by intravenous injection.
ACS nano 2012;6(6):5174-89.
2012: Qixian Chen; Taisuke Endo; Zhishen Ge; Takehiko Ishii; Keiji Itaka; Mitsunobu R Kano; Hiroaki Kinoh; Makoto Oba; Kensuke Osada; Theofilus A Tockary; Satoshi Uchida; Kazunori Kataoka
Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors.
Biomaterials 2012;33(18):4722-30.
2012: Satoshi Uchida; Kensuke Osada; Masa-Aki Shibata; Qixian Chen; Mariko Harada-Shiba; Takehiko Ishii; Keiji Itaka; Kazunori Kataoka
PEGylated polyplex with optimized PEG shielding enhances gene introduction in lungs by minimizing inflammatory responses.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(6):1196-203.
2012: Md Rafi; Masakazu Yashiro; P Mi; Kohei Miyazono; Nobuhiro Nishiyama; Horacio Cabral; Kosei Hirakawa; Caname Iwata; Mitsunobu R Kano; Kazunori Kataoka
Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis.
Journal of controlled release : official journal of the Controlled Release Society 2012;159(2):189-96.
2012: Kanjiro Miyata; Nobuhiro Nishiyama; Kazunori Kataoka
Rational design of smart supramolecular assemblies for gene delivery: chemical challenges in the creation of artificial viruses.
Chemical Society reviews 2012;41(7):2562-74.
2012: Hitomi Hosoya; Hideaki Ijichi; Koji Kadowaki; Kazunori Kataoka; Kazuhiko Koike; Michiya Matsusaki; Kohei Miyazono; Hiroshi Nishihara; Mitsuru Akashi; Horacio Cabral; Mitsunobu R Kano
Engineering fibrotic tissue in pancreatic cancer: a novel three-dimensional model to investigate nanoparticle delivery.
Biochemical and biophysical research communications 2012;419(1):32-7.
2012: Tomoya Suma; Hirokuni Uchida; Satoshi Uchida; Takehiko Ishii; Keiji Itaka; Kanjiro Miyata; Nobuhiro Nishiyama; Kazunori Kataoka
Enhanced stability and gene silencing ability of siRNA-loaded polyion complexes formulated from polyaspartamide derivatives with a repetitive array of amino groups in the side chain.
Biomaterials 2012;33(9):2770-9.
2012: Takahiro Nomoto; Makoto Oba; Kazuko Toh; Horacio Cabral; R James Christie; Shigeto Fukushima; Yu Matsumoto; Kanjiro Miyata; Mami Murakami; Nobuhiro Nishiyama; Kazunori Kataoka
[Evaluation of the dynamics of drug delivery systems (DDS) using intravital real-time confocal laser scanning microscopy].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2012;132(12):1347-54.
2012: Kensuke Osada; Hiroki Oshima; Tomonori Shiotani; Theofilus A Tockary; R. James Christie; Sorato Ikeda; Keiji Itaka; Daigo Kobayashi; Kazunori Kataoka
Enhanced gene expression promoted by the quantized folding of pDNA within polyplex micelles.
Biomaterials 2012;33(1):325-32.
2011: Stephanie Herlambang; Souta Horie; Shigeto Fukushima; Michiaki Kumagai; Kozo Miyazaki; Yuji Morimoto; Nobuhiro Nishiyama; Takahiro Nomoto; Makoto Oba; Kazunori Kataoka
Disulfide crosslinked polyion complex micelles encapsulating dendrimer phthalocyanine directed to improved efficiency of photodynamic therapy.
Journal of controlled release : official journal of the Controlled Release Society 2011;155(3):449-57.
2011: Satoshi Uchida; Kanjiro Miyata; Kensuke Osada; Qixian Chen; Mariko Harada-Shiba; Takehiko Ishii; Keiji Itaka; Kazunori Kataoka
Combination of chondroitin sulfate and polyplex micelles from Poly(ethylene glycol)-poly{N'-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} block copolymer for prolonged in vivo gene transfection with reduced toxicity.
Journal of controlled release : official journal of the Controlled Release Society 2011;155(2):296-302.
2011: Horacio Cabral; Nobuhiro Nishiyama; Kazunori Kataoka
Supramolecular nanodevices: from design validation to theranostic nanomedicine.
Accounts of chemical research 2011;44(10):999-1008.
2011: Hirokuni Uchida; Takehiko Ishii; Keiji Itaka; Kanjiro Miyata; Nobuhiro Nishiyama; Makoto Oba; Tomoya Suma; Kazunori Kataoka
Odd-even effect of repeating aminoethylene units in the side chain of N-substituted polyaspartamides on gene transfection profiles.
Journal of the American Chemical Society 2011;133(39):15524-32.
2011: R. James Christie; Shigeto Fukushima; Tzai Chung Lai; Yu Matsumoto; Daniel Menasco; Kanjiro Miyata; Nobuhiro Nishiyama; Takahiro Nomoto; Kensuke Osada; Matthew Pennisi; Yuichi Yamasaki; Kazunori Kataoka
Effect of polymer structure on micelles formed between siRNA and cationic block copolymer comprising thiols and amidines.
Biomacromolecules 2011;12(9):3174-85.
2011: Tsz Chung Lai; Kazunori Kataoka; Glen S Kwon
Pluronic-based cationic block copolymer for forming pDNA polyplexes with enhanced cellular uptake and improved transfection efficiency.
Biomaterials 2011;32(20):4594-603.
2011: Yasutaka Anraku; Akihiro Kishimura; Atsushi Kobayashi; Makoto Oba; Kazunori Kataoka
Size-controlled long-circulating PICsome as a ruler to measure critical cut-off disposition size into normal and tumor tissues.
Chemical communications (Cambridge, England) 2011;47(21):6054-6.
2011: Takahiro Nomoto; Yu Matsumoto; Kanjiro Miyata; Makoto Oba; Shigeto Fukushima; Nobuhiro Nishiyama; Tatsuya Yamasoba; Kazunori Kataoka
In situ quantitative monitoring of polyplexes and polyplex micelles in the blood circulation using intravital real-time confocal laser scanning microscopy.
Journal of controlled release : official journal of the Controlled Release Society 2011;151(2):104-9.
2011: Frederico Pittella; Mingzhen Zhang; Yan Lee; Hyun J Kim; Theofilus Tockary; Kensuke Osada; Takehiko Ishii; Kanjiro Miyata; Nobuhiro Nishiyama; Kazunori Kataoka
Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity.
Biomaterials 2011;32(11):3106-14.
2011: Mami Murakami; Horacio Cabral; Yu Matsumoto; Shourong Wu; Mitsunobu R Kano; Takao Yamori; Nobuhiro Nishiyama; Kazunori Kataoka
Improving drug potency and efficacy by nanocarrier-mediated subcellular targeting.
Science translational medicine 2011;3(64):64ra2.
2011: Yelena Vachutinsky; Makoto Oba; Kanjiro Miyata; Shigehiro Hiki; Mitsunobu R Kano; Nobuhiro Nishiyama; Hiroyuki Koyama; Kohei Miyazono; Kazunori Kataoka
Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles.
Journal of controlled release : official journal of the Controlled Release Society 2011;149(1):51-7.
2011: Makoto Oba; Kanjiro Miyata; Kensuke Osada; R. James Christie; Mai Sanjoh; Weidong Li; Shigeto Fukushima; Takehiko Ishii; Mitsunobu R Kano; Nobuhiro Nishiyama; Hiroyuki Koyama; Kazunori Kataoka
Polyplex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery.
Biomaterials 2011;32(2):652-63.
2010: Kazumitsu Ueda; T Watadani; Eriko Maeda; S Ota; Kazunori Kataoka; S Seo; K Kumano; Akira Hangaishi; Tokiharu Takahashi; Yasuharu Imai; Kuni Ohtomo; Masashi Fukayama; Yasuhito Nannya; Mineo Kurokawa
Outcome and treatment of late-onset noninfectious pulmonary complications after allogeneic haematopoietic SCT.
Bone marrow transplantation 2010;45(12):1719-27.
2010: Hiroyasu Takemoto; Atsushi Ishii; Kanjiro Miyata; Masataka Nakanishi; Makoto Oba; Takehiko Ishii; Yuichi Yamasaki; Nobuhiro Nishiyama; Kazunori Kataoka
Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system.
Biomaterials 2010;31(31):8097-105.
2010: Tsz Chung Lai; Younsoo Bae; Takayuki Yoshida; Kazunori Kataoka; Glen S Kwon
pH-sensitive multi-PEGylated block copolymer as a bioresponsive pDNA delivery vector.
Pharmaceutical research 2010;27(11):2260-73.
2010: Sachiko Kaida; Horacio Cabral; Michiaki Kumagai; Akihiro Kishimura; Yasuko Terada; Masaki Sekino; Ichio Aoki; Nobuhiro Nishiyama; Toru Tani; Kazunori Kataoka
Visible drug delivery by supramolecular nanocarriers directing to single-platformed diagnosis and therapy of pancreatic tumor model.
Cancer research 2010;70(18):7031-41.
2010: Kensuke Osada; Hiroki Oshima; Daigo Kobayashi; Motoyoshi Doi; Manabu Enoki; Yuichi Yamasaki; Kazunori Kataoka
Quantized folding of plasmid DNA condensed with block catiomer into characteristic rod structures promoting transgene efficacy.
Journal of the American Chemical Society 2010;132(35):12343-8.
2010: Michiaki Kumagai; Tridib Kumar Sarma; Horacio Cabral; Sachiko Kaida; Masaki Sekino; Nicholas Herlambang; Kensuke Osada; Mitsunobu R Kano; Nobuhiro Nishiyama; Kazunori Kataoka
Enhanced in vivo Magnetic Resonance Imaging of Tumors by PEGylated Iron-Oxide-Gold Core-Shell Nanoparticles with Prolonged Blood Circulation Properties.
Macromolecular rapid communications 2010;31(17):1521-8.
2010: Akira Matsumoto; Horacio Cabral; Naoko Sato; Kazunori Kataoka; Yuji Miyahara
Assessment of tumor metastasis by the direct determination of cell-membrane sialic acid expression.
Angewandte Chemie (International ed. in English) 2010;49(32):5494-7.
2010: Hyun Jin Kim; Atsushi Ishii; Kanjiro Miyata; Yan Lee; Shourong Wu; Makoto Oba; Nobuhiro Nishiyama; Kazunori Kataoka
Introduction of stearoyl moieties into a biocompatible cationic polyaspartamide derivative, PAsp(DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown.
Journal of controlled release : official journal of the Controlled Release Society 2010;145(2):141-8.
2010: Mai Sanjoh; Shigehiro Hiki; Yan Lee; Makoto Oba; Kanjiro Miyata; Takehiko Ishii; Kazunori Kataoka
pDNA/poly(L-lysine) Polyplexes Functionalized with a pH-Sensitive Charge-Conversional Poly(aspartamide) Derivative for Controlled Gene Delivery to Human Umbilical Vein Endothelial Cells.
Macromolecular rapid communications 2010;31(13):1181-6.
2010: Kanjiro Miyata; Noha Gouda; Hiroyasu Takemoto; Makoto Oba; Yan Lee; Hiroyuki Koyama; Yuichi Yamasaki; Keiji Itaka; Nobuhiro Nishiyama; Kazunori Kataoka
Enhanced transfection with silica-coated polyplexes loading plasmid DNA.
Biomaterials 2010;31(17):4764-70.
2010: Wankee Kim; Yuichi Yamasaki; woo-dong Jang; Kazunori Kataoka
Thermodynamics of DNA condensation induced by poly(ethylene glycol)-block-polylysine through polyion complex micelle formation.
Biomacromolecules 2010;11(5):1180-6.
2010: Keiji Itaka; Takehiko Ishii; Yoko Hasegawa; Kazunori Kataoka
Biodegradable polyamino acid-based polycations as safe and effective gene carrier minimizing cumulative toxicity.
Biomaterials 2010;31(13):3707-14.
2010: Akira Matsumoto; Kazuya Yamamoto; Ryo Yoshida; Kazunori Kataoka; Takao Aoyagi; Yuji Miyahara
A totally synthetic glucose responsive gel operating in physiological aqueous conditions.
Chemical communications (Cambridge, England) 2010;46(13):2203-5.
2010: Makoto Oba; Yelena Vachutinsky; Kanjiro Miyata; Mitsunobu R Kano; Sorato Ikeda; Nobuhiro Nishiyama; Keiji Itaka; Kohei Miyazono; Hiroyuki Koyama; Kazunori Kataoka
Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble flt-1.
Molecular pharmaceutics 2010;7(2):501-9.
2010: Keiji Itaka; Kensuke Osada; Katsue Morii; Pilhan Kim; Seok-Hyun Yun; Kazunori Kataoka
Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle.
Journal of controlled release : official journal of the Controlled Release Society 2010;143(1):112-9.
2010: Hideki Shimizu; Yuichi Hori; Shinya Kaname; Koei Yamada; Nobuhiro Nishiyama; Satoru Matsumoto; Kanjiro Miyata; Makoto Oba; Akira Yamada; Kazunori Kataoka; Toshiro Fujita
siRNA-based therapy ameliorates glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2010;21(4):622-33.
2010: Shigehiro Hiki; Kazunori Kataoka
Versatile and selective synthesis of "click chemistry" compatible heterobifunctional poly(ethylene glycol)s possessing azide and alkyne functionalities.
Bioconjugate chemistry 2010;21(2):248-54.
2010: Yasutaka Anraku; Akihiro Kishimura; Makoto Oba; Yuichi Yamasaki; Kazunori Kataoka
Spontaneous formation of nanosized unilamellar polyion complex vesicles with tunable size and properties.
Journal of the American Chemical Society 2010;132(5):1631-6.
2009: Michiaki Kumagai; Mitsunobu R Kano; Yasuyuki Morishita; Motomi Ota; Yutaka Imai; Nobuhiro Nishiyama; Masaki Sekino; Shoogo Ueno; Kohei Miyazono; Kazunori Kataoka
Enhanced magnetic resonance imaging of experimental pancreatic tumor in vivo by block copolymer-coated magnetite nanoparticles with TGF-beta inhibitor.
Journal of controlled release : official journal of the Controlled Release Society 2009;140(3):306-11.
2009: Akira Matsumoto; Naoko Sato; Kazunori Kataoka; Yuji Miyahara
Noninvasive sialic acid detection at cell membrane by using phenylboronic acid modified self-assembled monolayer gold electrode.
Journal of the American Chemical Society 2009;131(34):12022-3.
2009: Younsoo Bae; Kazunori Kataoka
Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymers.
Advanced drug delivery reviews 2009;61(10):768-84.
2009: Muri Han; Makoto Oba; Nobuhiro Nishiyama; Mitsunobu R Kano; Shinae Kizaka-Kondoh; Kazunori Kataoka
Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(8):1404-10.
2009: Yu Matsumoto; Keiji Itaka; Tatsuya Yamasoba; Kazunori Kataoka
Intranuclear fluorescence resonance energy transfer analysis of plasmid DNA decondensation from nonviral gene carriers.
The journal of gene medicine 2009;11(7):615-23.
2009: Kensuke Osada; R. James Christie; Kazunori Kataoka
Polymeric micelles from poly(ethylene glycol)-poly(amino acid) block copolymer for drug and gene delivery.
Journal of the Royal Society, Interface / the Royal Society 2009;6 Suppl 3():S325-39.
2009: Wenjie Wang; Keiji Itaka; Shinsuke Ohba; Nobuhiro Nishiyama; Ung-il Chung; Yuichi Yamasaki; Kazunori Kataoka
3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells.
Biomaterials 2009;30(14):2705-15.
2009: Nobuhiro Nishiyama; Yuji Morimoto; woo-dong Jang; Kazunori Kataoka
Design and development of dendrimer photosensitizer-incorporated polymeric micelles for enhanced photodynamic therapy.
Advanced drug delivery reviews 2009;61(4):327-38.
2009: Wen-Fei Dong; Akihiro Kishimura; Yasutaka Anraku; Sayan Chuanoi; Kazunori Kataoka
Monodispersed polymeric nanocapsules: spontaneous evolution and morphology transition from reducible hetero-PEG PICmicelles by controlled degradation.
Journal of the American Chemical Society 2009;131(11):3804-5.
2009: Nobuhiro Nishiyama; Kazunori Kataoka
[Development of polymeric micelles for the delivery of antitumor agents].
Gan to kagaku ryoho. Cancer & chemotherapy 2009;36(3):357-61.
2009: Keiji Itaka; Kazunori Kataoka
Recent development of nonviral gene delivery systems with virus-like structures and mechanisms.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2009;71(3):475-83.
2009: Nobuhiro Nishiyama; Yoshinori Nakagishi; Yuji Morimoto; Ping-Shan Lai; Kozo Miyazaki; Kyoko Urano; Souta Horie; Michiaki Kumagai; Shigeto Fukushima; Yu Cheng; woo-dong Jang; Makoto Kikuchi; Kazunori Kataoka
Enhanced photodynamic cancer treatment by supramolecular nanocarriers charged with dendrimer phthalocyanine.
Journal of controlled release : official journal of the Controlled Release Society 2009;133(3):245-51.
2009: Satoru Matsumoto; R. James Christie; Nobuhiro Nishiyama; Kanjiro Miyata; Atsushi Ishii; Makoto Oba; Hiroyuki Koyama; Yuichi Yamasaki; Kazunori Kataoka
Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery.
Biomacromolecules 2009;10(1):119-27.
2009: Hidehiro Oana; Akihiro Kishimura; Kei Yonehara; Yuichi Yamasaki; Masao Washizu; Kazunori Kataoka
Spontaneous formation of giant unilamellar vesicles from microdroplets of a polyion complex by thermally induced phase separation.
Angewandte Chemie (International ed. in English) 2009;48(25):4613-6.
2009: Yan Lee; Takehiko Ishii; Horacio Cabral; Hyun Jin Kim; Ji-Hun Seo; Nobuhiro Nishiyama; Hiroki Oshima; Kensuke Osada; Kazunori Kataoka
Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm.
Angewandte Chemie (International ed. in English) 2009;48(29):5309-12.
2009: Mitsunobu R Kano; Yukari Komuta; Caname Iwata; Masako Oka; Yo-taro Shirai; Yasuyuki Morishita; Yasuyoshi Ouchi; Kazunori Kataoka; Kohei Miyazono
Comparison of the effects of the kinase inhibitors imatinib, sorafenib, and transforming growth factor-beta receptor inhibitor on extravasation of nanoparticles from neovasculature.
Cancer science 2009;100(1):173-80.
2008: Kanjiro Miyata; Makoto Oba; Masataka Nakanishi; Shigeto Fukushima; Yuichi Yamasaki; Hiroyuki Koyama; Nobuhiro Nishiyama; Kazunori Kataoka
Polyplexes from poly(aspartamide) bearing 1,2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity.
Journal of the American Chemical Society 2008;130(48):16287-94.
2008: Kanjiro Miyata; Makoto Oba; Mitsunobu R Kano; Shigeto Fukushima; Yelena Vachutinsky; Muri Han; Hiroyuki Koyama; Kohei Miyazono; Nobuhiro Nishiyama; Kazunori Kataoka
Polyplex micelles from triblock copolymers composed of tandemly aligned segments with biocompatible, endosomal escaping, and DNA-condensing functions for systemic gene delivery to pancreatic tumor tissue.
Pharmaceutical research 2008;25(12):2924-36.
2008: Makoto Oba; Kazuhiro Aoyagi; Kanjiro Miyata; Yu Matsumoto; Keiji Itaka; Nobuhiro Nishiyama; Yuichi Yamasaki; Hiroyuki Koyama; Kazunori Kataoka
Polyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking.
Molecular pharmaceutics 2008;5(6):1080-92.
2008: Shourong Wu; Nobuhiro Nishiyama; Mitsunobu R Kano; Yasuyuki Morishita; Kohei Miyazono; Keiji Itaka; Ung-il Chung; Kazunori Kataoka
Enhancement of angiogenesis through stabilization of hypoxia-inducible factor-1 by silencing prolyl hydroxylase domain-2 gene.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(7):1227-34.
2008: Seiji Takae; Kanjiro Miyata; Makoto Oba; Takehiko Ishii; Nobuhiro Nishiyama; Keiji Itaka; Yuichi Yamasaki; Hiroyuki Koyama; Kazunori Kataoka
PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors.
Journal of the American Chemical Society 2008;130(18):6001-9.
2008: Kenji Sugisaki; Tomohiko Usui; Nobuhiro Nishiyama; woo-dong Jang; Yasuo Yanagi; Satoru Yamagami; Shiro Amano; Kazunori Kataoka
Photodynamic therapy for corneal neovascularization using polymeric micelles encapsulating dendrimer porphyrins.
Investigative ophthalmology & visual science 2008;49(3):894-9.
2008: Shourong Wu; Saomi Murai; Kazunori Kataoka; Makoto Miyagishi
Yin Yang 1 induces transcriptional activity of p73 through cooperation with E2F1.
Biochemical and biophysical research communications 2008;365(1):75-81.
2008: Yan Lee; Kanjiro Miyata; Makoto Oba; Takehiko Ishii; Shigeto Fukushima; Muri Han; Hiroyuki Koyama; Nobuhiro Nishiyama; Kazunori Kataoka
Charge-conversion ternary polyplex with endosome disruption moiety: a technique for efficient and safe gene delivery.
Angewandte Chemie (International ed. in English) 2008;47(28):5163-6.
2007: Kayo Masago; Keiji Itaka; Nobuhiro Nishiyama; Ung-il Chung; Kazunori Kataoka
Gene delivery with biocompatible cationic polymer: pharmacogenomic analysis on cell bioactivity.
Biomaterials 2007;28(34):5169-75.
2007: Shigehiro Hiki; Kazunori Kataoka
A facile synthesis of azido-terminated heterobifunctional poly(ethylene glycol)s for "click" conjugation.
Bioconjugate chemistry 2007;18(6):2191-6.
2007: Kanjiro Miyata; Shigeto Fukushima; Nobuhiro Nishiyama; Yuichi Yamasaki; Kazunori Kataoka
PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high transfection efficacy.
Journal of controlled release : official journal of the Controlled Release Society 2007;122(3):252-60.
2007: Makoto Oba; Shigeto Fukushima; Naoki Kanayama; Kazuhiro Aoyagi; Nobuhiro Nishiyama; Hiroyuki Koyama; Kazunori Kataoka
Cyclic RGD peptide-conjugated polyplex micelles as a targetable gene delivery system directed to cells possessing alphavbeta3 and alphavbeta5 integrins.
Bioconjugate chemistry 2007;18(5):1415-23.
2007: May Xiong; Younsoo Bae; Shigeto Fukushima; M Laird Forrest; Nobuhiro Nishiyama; Kazunori Kataoka; Glen S Kwon
pH-responsive Multi-PEGylated dual cationic nanoparticles enable charge modulations for safe gene delivery.
ChemMedChem 2007;2(9):1321-7.
2007: Keiji Itaka; Shinsuke Ohba; Kanjiro Miyata; Hiroshi Kawaguchi; Kozo Nakamura; Tsuyoshi Takato; Ung-il Chung; Kazunori Kataoka
Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(9):1655-62.
2007: Motoi Oishi; Yukio Nagasaki; Nobuhiro Nishiyama; Keiji Itaka; Motoki Takagi; Akira Shimamoto; Yasuhiro Furuichi; Kazunori Kataoka
Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly(ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes.
ChemMedChem 2007;2(9):1290-7.
2007: Horacio Cabral; Nobuhiro Nishiyama; Kazunori Kataoka
Optimization of (1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity.
Journal of controlled release : official journal of the Controlled Release Society 2007;121(3):146-55.
2007: Muri Han; Younsoo Bae; Nobuhiro Nishiyama; Kanjiro Miyata; Makoto Oba; Kazunori Kataoka
Transfection study using multicellular tumor spheroids for screening non-viral polymeric gene vectors with low cytotoxicity and high transfection efficiencies.
Journal of controlled release : official journal of the Controlled Release Society 2007;121(1-2):38-48.
2007: Seiji Takae; Yoshitsugu Akiyama; Yuichi Yamasaki; Yukio Nagasaki; Kazunori Kataoka
Colloidal Au replacement assay for highly sensitive quantification of low molecular weight analytes by surface plasmon resonance.
Bioconjugate chemistry 2007;18(4):1241-5.
2007: Younsoo Bae; Nobuhiro Nishiyama; Kazunori Kataoka
In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments.
Bioconjugate chemistry 2007;18(4):1131-9.
2007: Daisuke Akagi; M Oba; Hiroyuki Koyama; Nobuhiro Nishiyama; S Fukushima; Toshio Miyata; Hirokazu Nagawa; Kazunori Kataoka
Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation.
Gene therapy 2007;14(13):1029-38.
2007: Yan Lee; Shigeto Fukushima; Younsoo Bae; Shigehiro Hiki; Takehiko Ishii; Kazunori Kataoka
A protein nanocarrier from charge-conversion polymer in response to endosomal pH.
Journal of the American Chemical Society 2007;129(17):5362-3.
2007: Michiaki Kumagai; Yutaka Imai; Teisaku Nakamura; Yuichi Yamasaki; Masaki Sekino; Shoogo Ueno; Kenjiro Hanaoka; Kazuya Kikuchi; Tetsuo Nagano; Eiji Kaneko; Kentaro Shimokado; Kazunori Kataoka
Iron hydroxide nanoparticles coated with poly(ethylene glycol)-poly(aspartic acid) block copolymer as novel magnetic resonance contrast agents for in vivo cancer imaging.
Colloids and surfaces. B, Biointerfaces 2007;56(1-2):174-81.
2007: Mitsunobu R Kano; Younsoo Bae; Caname Iwata; Yasuyuki Morishita; Masakazu Yashiro; Masako Oka; Tomoko Fujii; Akiyoshi Komuro; Kunihiko Kiyono; Michio Kaminishi; Kosei Hirakawa; Yasuyoshi Ouchi; Nobuhiro Nishiyama; Kazunori Kataoka; Kohei Miyazono
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3460-5.
2007: Joon-Sik Park; Yoshitsugu Akiyama; Yuichi Yamasaki; Kazunori Kataoka
Preparation and characterization of polyion complex micelles with a novel thermosensitive poly(2-isopropyl-2-oxazoline) shell via the complexation of oppositely charged block ionomers.
Langmuir : the ACS journal of surfaces and colloids 2007;23(1):138-46.
2007: Shourong Wu; Saomi Murai; Kazunori Kataoka; Makoto Miyagishi
Cooperative regulation of p73 promoter by Yin Yang 1 and E2F1.
Nucleic acids symposium series (2004) 2007;(51):347-8.
2007: Akihiro Kishimura; Aya Koide; Kensuke Osada; Yuichi Yamasaki; Kazunori Kataoka
Encapsulation of myoglobin in PEGylated polyion complex vesicles made from a pair of oppositely charged block ionomers: a physiologically available oxygen carrier.
Angewandte Chemie (International ed. in English) 2007;46(32):6085-8.
2006: Nobuhiro Nishiyama; Kazunori Kataoka
Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery.
Pharmacology & therapeutics 2006;112(3):630-48.
2006: A Arnida; Nobuhiro Nishiyama; woo-dong Jang; Yuichi Yamasaki; Kazunori Kataoka
Novel ternary polyplex of triblock copolymer, pDNA and anionic dendrimer phthalocyanine for photochemical enhancement of transgene expression.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):e75-7.
2006: Younsoo Bae; Kazunori Kataoka
Significant enhancement of antitumor activity and bioavailability of intracellular pH-sensitive polymeric micelles by folate conjugation.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):e49-50.
2006: Nobuhiro Nishiyama; Naoki Kanayama; woo-dong Jang; Yuichi Yamasaki; Kazunori Kataoka
PEGylated gene nanocarriers based on block catiomers bearing ethylenediamine repeating units directed to remarkable enhancement of photochemical transfection.
Journal of controlled release : official journal of the Controlled Release Society 2006;115(2):208-15.
2006: Younsoo Bae; Kazunori Kataoka
[Drug and gene delivery with nanotechnology].
Seikagaku. The Journal of Japanese Biochemical Society 2006;78(9):882-7.
2006: Nobuhiro Nishiyama; woo-dong Jang; Kotoe Date; Kanjiro Miyata; Kazunori Kataoka
Photochemical enhancement of transgene expression by polymeric micelles incorporating plasmid DNA and dendrimer-based photosensitizer.
Journal of drug targeting 2006;14(6):413-24.
2006: woo-dong Jang; Yoshinori Nakagishi; Nobuhiro Nishiyama; Satoko Kawauchi; Yuji Morimoto; Makoto Kikuchi; Kazunori Kataoka
Polyion complex micelles for photodynamic therapy: incorporation of dendritic photosensitizer excitable at long wavelength relevant to improved tissue-penetrating property.
Journal of controlled release : official journal of the Controlled Release Society 2006;113(1):73-9.
2006: Wankee Kim; Yuichi Yamasaki; Kazunori Kataoka
Development of a fitting model suitable for the isothermal titration calorimetric curve of DNA with cationic ligands.
The journal of physical chemistry. B 2006;110(22):10919-25.
2006: Aya Koide; Akihiro Kishimura; Kensuke Osada; woo-dong Jang; Yuichi Yamasaki; Kazunori Kataoka
Semipermeable polymer vesicle (PICsome) self-assembled in aqueous medium from a pair of oppositely charged block copolymers: physiologically stable micro-/nanocontainers of water-soluble macromolecules.
Journal of the American Chemical Society 2006;128(18):5988-9.
2006: Motoi Oishi; Kazunori Kataoka; Yukio Nagasaki
pH-responsive three-layered PEGylated polyplex micelle based on a lactosylated ABC triblock copolymer as a targetable and endosome-disruptive nonviral gene vector.
Bioconjugate chemistry 2006;17(3):677-88.
2006: Naoki Kanayama; Shigeto Fukushima; Nobuhiro Nishiyama; Keiji Itaka; woo-dong Jang; Kanjiro Miyata; Yuichi Yamasaki; Ung-il Chung; Kazunori Kataoka
A PEG-based biocompatible block catiomer with high buffering capacity for the construction of polyplex micelles showing efficient gene transfer toward primary cells.
ChemMedChem 2006;1(4):439-44.
2006: Shoogo Ueno; Joji Ando; Hiroyuki Fujita; Tadashi Sugawara; Yasuhiko Jimbo; Keiji Itaka; Kazunori Kataoka; Takashi Ushida
The state of the art of nanobioscience in Japan.
IEEE transactions on nanobioscience 2006;5(1):54-65.
2006: Keiji Itaka; Ung-il Chung; Kazunori Kataoka
[Supramolecular nanocarrier for gene and siRNA delivery].
Nihon rinsho. Japanese journal of clinical medicine 2006;64(2):253-7.
2006: Nobuhiro Nishiyama; Kazunori Kataoka
[Nano-engineering for biomedical applications].
Nihon rinsho. Japanese journal of clinical medicine 2006;64(2):199-205.
2005: Kanjiro Miyata; Yoshinori Kakizawa; Nobuhiro Nishiyama; Yuichi Yamasaki; Tsunamasa Watanabe; Michinori Kohara; Kazunori Kataoka
Freeze-dried formulations for in vivo gene delivery of PEGylated polyplex micelles with disulfide crosslinked cores to the liver.
Journal of controlled release : official journal of the Controlled Release Society 2005;109(1-3):15-23.
2005: Ryuichi Ideta; Fumitaka Tasaka; woo-dong Jang; Nobuhiro Nishiyama; Guo-Dong Zhang; Atsushi Harada; Yasuo Yanagi; Yasuhiro Tamaki; Takuzo Aida; Kazunori Kataoka
Nanotechnology-based photodynamic therapy for neovascular disease using a supramolecular nanocarrier loaded with a dendritic photosensitizer.
Nano letters 2005;5(12):2426-31.
2005: Nobuhiro Nishiyama; Aya Iriyama; woo-dong Jang; Kanjiro Miyata; Keiji Itaka; Yuji Inoue; Hidenori Takahashi; Yasuo Yanagi; Yasuhiro Tamaki; Hiroyuki Koyama; Kazunori Kataoka
Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer.
Nature materials 2005;4(12):934-41.
2005: Nobuhiro Nishiyama; Kazunori Kataoka
[Medical applications of nanotechnology: polymeric micelles for drug delivery].
Nihon Geka Gakkai zasshi 2005;106(11):700-5.
2005: Tomohiko Usui; Kenji Sugisaki; Shiro Amano; woo-dong Jang; Nobuhiro Nishiyama; Kazunori Kataoka
New drug delivery for corneal neovascularization using polyion complex micelles.
Cornea 2005;24(8 Suppl):S39-S42.
2005: Younsoo Bae; woo-dong Jang; Nobuhiro Nishiyama; Shigeto Fukushima; Kazunori Kataoka
Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery.
Molecular bioSystems 2005;1(3):242-50.
2005: Motoi Oishi; Tetsuya Hayama; Yoshitsugu Akiyama; Seiji Takae; Atsushi Harada; Yuichi Yamasaki; Fumi Nagatsugi; Shigeki Sasaki; Yukio Nagasaki; Kazunori Kataoka
Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide: polyion complex (PIC) micelles based on poly(ethylene glycol)-SS-oligodeoxynucleotide conjugate.
Biomacromolecules 2005;6(5):2449-54.
2005: Kensuke Osada; Yuichi Yamasaki; Satoshi Katayose; Kazunori Kataoka
A synthetic block copolymer regulates S1 nuclease fragmentation of supercoiled plasmid DNA.
Angewandte Chemie (International ed. in English) 2005;44(23):3544-8.
2005: Motoi Oishi; Fumi Nagatsugi; Shigeki Sasaki; Yukio Nagasaki; Kazunori Kataoka
Smart polyion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotides containing acid-labile linkages.
Chembiochem : a European journal of chemical biology 2005;6(4):718-25.
2005: Xiaofei Yuan; Atsushi Harada; Yuichi Yamasaki; Kazunori Kataoka
Stabilization of lysozyme-incorporated polyion complex micelles by the omega-end derivatization of poly(ethylene glycol)-poly(alpha,beta-aspartic acid) block copolymers with hydrophobic groups.
Langmuir : the ACS journal of surfaces and colloids 2005;21(7):2668-74.
2005: Shigeto Fukushima; Kanjiro Miyata; Nobuhiro Nishiyama; Naoki Kanayama; Yuichi Yamasaki; Kazunori Kataoka
PEGylated polyplex micelles from triblock catiomers with spatially ordered layering of condensed pDNA and buffering units for enhanced intracellular gene delivery.
Journal of the American Chemical Society 2005;127(9):2810-1.
2005: Seiji Takae; Yoshitsugu Akiyama; Hidenori Otsuka; Teisaku Nakamura; Yukio Nagasaki; Kazunori Kataoka
Ligand density effect on biorecognition by PEGylated gold nanoparticles: regulated interaction of RCA120 lectin with lactose installed to the distal end of tethered PEG strands on gold surface.
Biomacromolecules 2005;6(2):818-24.
2005: Motoi Oishi; Yukio Nagasaki; Keiji Itaka; Nobuhiro Nishiyama; Kazunori Kataoka
Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells.
Journal of the American Chemical Society 2005;127(6):1624-5.
2005: woo-dong Jang; Nobuhiro Nishiyama; Guo-Dong Zhang; Atsushi Harada; Dong-Lin Jiang; Satoko Kawauchi; Yuji Morimoto; Makoto Kikuchi; Hiroyuki Koyama; Takuzo Aida; Kazunori Kataoka
Supramolecular nanocarrier of anionic dendrimer porphyrins with cationic block copolymers modified with polyethylene glycol to enhance intracellular photodynamic efficacy.
Angewandte Chemie (International ed. in English) 2005;44(3):419-23.
2005: Horacio Cabral; Nobuhiro Nishiyama; Soichiro Okazaki; Hiroyuki Koyama; Kazunori Kataoka
Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles.
Journal of controlled release : official journal of the Controlled Release Society 2005;101(1-3):223-32.
2005: Kazunori Kataoka; Keiji Itaka; Nobuhiro Nishiyama; Yuichi Yamasaki; Motoi Oishi; Yukio Nagasaki
Smart polymeric micelles as nanocarriers for oligonucleotides and siRNA delivery.
Nucleic acids symposium series (2004) 2005;(49):17-8.
2005: Younsoo Bae; Nobuhiro Nishiyama; Shigeto Fukushima; Hiroyuki Koyama; Matsumura Yasuhiro; Kazunori Kataoka
Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy.
Bioconjugate chemistry 2005;16(1):122-30.
2004: Hidenori Otsuka; Yukio Nagasaki; Kazunori Kataoka
Characterization of aldehyde-PEG tethered surfaces: influence of PEG chain length on the specific biorecognition.
Langmuir : the ACS journal of surfaces and colloids 2004;20(26):11285-7.
2004: Daisuke Wakebayashi; Nobuhiro Nishiyama; Keiji Itaka; Kanjiro Miyata; Yuichi Yamasaki; Atsushi Harada; Hiroyuki Koyama; Yukio Nagasaki; Kazunori Kataoka
Polyion complex micelles of pDNA with acetal-poly(ethylene glycol)-poly(2-(dimethylamino)ethyl methacrylate) block copolymer as the gene carrier system: physicochemical properties of micelles relevant to gene transfection efficacy.
Biomacromolecules 2004;5(6):2128-36.
2004: Keiji Itaka; Naoki Kanayama; Nobuhiro Nishiyama; woo-dong Jang; Yuichi Yamasaki; Kozo Nakamura; Hiroshi Kawaguchi; Kazunori Kataoka
Supramolecular nanocarrier of siRNA from PEG-based block catiomer carrying diamine side chain with distinctive pKa directed to enhance intracellular gene silencing.
Journal of the American Chemical Society 2004;126(42):13612-3.
2004: Eduardo Jule; Yuji Yamamoto; Muriel Thouvenin; Yukio Nagasaki; Kazunori Kataoka
Thermal characterization of poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles based on pyrene excimer formation.
Journal of controlled release : official journal of the Controlled Release Society 2004;97(3):407-19.
2004: Hidenori Otsuka; Akihiro Hirano; Yukio Nagasaki; Teruo Okano; Yasuhiro Horiike; Kazunori Kataoka
Two-dimensional multiarray formation of hepatocyte spheroids on a microfabricated PEG-brush surface.
Chembiochem : a European journal of chemical biology 2004;5(6):850-5.
2004: Akira Matsumoto; Ryo Yoshida; Kazunori Kataoka
Glucose-responsive polymer gel bearing phenylborate derivative as a glucose-sensing moiety operating at the physiological pH.
Biomacromolecules 2004;5(3):1038-45.
2004: Daisuke Wakebayashi; Nobuhiro Nishiyama; Yuichi Yamasaki; Keiji Itaka; Naoki Kanayama; Atsushi Harada; Yukio Nagasaki; Kazunori Kataoka
Lactose-conjugated polyion complex micelles incorporating plasmid DNA as a targetable gene vector system: their preparation and gene transfecting efficiency against cultured HepG2 cells.
Journal of controlled release : official journal of the Controlled Release Society 2004;95(3):653-64.
2004: Kanjiro Miyata; Yoshinori Kakizawa; Nobuhiro Nishiyama; Atsushi Harada; Yuichi Yamasaki; Hiroyuki Koyama; Kazunori Kataoka
Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression.
Journal of the American Chemical Society 2004;126(8):2355-61.
2004: Yoshitsugu Akiyama; Yukio Nagasaki; Kazunori Kataoka
Synthesis of heterotelechelic poly(ethylene glycol) derivatives having alpha-benzaldehyde and omega-pyridyl disulfide groups by ring opening polymerization of ethylene oxide using 4-(diethoxymethyl)benzyl alkoxide as a novel initiator.
Bioconjugate chemistry 2004;15(2):424-7.
2004: Montree Jaturanpinyo; Atsushi Harada; Xiaofei Yuan; Kazunori Kataoka
Preparation of bionanoreactor based on core-shell structured polyion complex micelles entrapping trypsin in the core cross-linked with glutaraldehyde.
Bioconjugate chemistry 2004;15(2):344-8.
2004: Ryuichi Ideta; Yasuo Yanagi; Yasuhiro Tamaki; Fumitaka Tasaka; Atsushi Harada; Kazunori Kataoka
Effective accumulation of polyion complex micelle to experimental choroidal neovascularization in rats.
FEBS letters 2004;557(1-3):21-5.
2004: Keiji Itaka; Atsushi Harada; Yuichi Yamasaki; Kozo Nakamura; Hiroshi Kawaguchi; Kazunori Kataoka
In situ single cell observation by fluorescence resonance energy transfer reveals fast intra-cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine.
The journal of gene medicine 2004;6(1):76-84.
2003: Nobuhiro Nishiyama; Souichiro Okazaki; Horacio Cabral; Masaki Miyamoto; Yukio Kato; Yuichi Sugiyama; Kazuto Nishio; Yasuhiro Matsumura; Kazunori Kataoka
Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice.
Cancer research 2003;63(24):8977-83.
2003: Guo-Dong Zhang; Atsushi Harada; Nobuhiro Nishiyama; Dong-Lin Jiang; Hiroyuki Koyama; Takuzo Aida; Kazunori Kataoka
Polyion complex micelles entrapping cationic dendrimer porphyrin: effective photosensitizer for photodynamic therapy of cancer.
Journal of controlled release : official journal of the Controlled Release Society 2003;93(2):141-50.
2003: Keiji Itaka; Kyosuke Yamauchi; Atsushi Harada; Kozo Nakamura; Hiroshi Kawaguchi; Kazunori Kataoka
Polyion complex micelles from plasmid DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer as serum-tolerable polyplex system: physicochemical properties of micelles relevant to gene transfection efficiency.
Biomaterials 2003;24(24):4495-506.
2003: Younsoo Bae; Shigeto Fukushima; Atsushi Harada; Kazunori Kataoka
Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change.
Angewandte Chemie (International ed. in English) 2003;42(38):4640-3.
2003: Motoi Oishi; Shigeki Sasaki; Yukio Nagasaki; Kazunori Kataoka
pH-responsive oligodeoxynucleotide (ODN)-poly(ethylene glycol) conjugate through acid-labile beta-thiopropionate linkage: preparation and polyion complex micelle formation.
Biomacromolecules 2003;4(5):1426-32.
2003: Akira Matsumoto; Syuhei Ikeda; Atsushi Harada; Kazunori Kataoka
Glucose-responsive polymer bearing a novel phenylborate derivative as a glucose-sensing moiety operating at physiological pH conditions.
Biomacromolecules 2003;4(5):1410-6.
2003: Hidenori Otsuka; Eiichiro Uchimura; Hiroyuki Koshino; Teruo Okano; Kazunori Kataoka
Anomalous binding profile of phenylboronic acid with N-acetylneuraminic acid (Neu5Ac) in aqueous solution with varying pH.
Journal of the American Chemical Society 2003;125(12):3493-502.
2003: Nobuhiro Nishiyama; Fumiaki Koizumi; Soichiro Okazaki; Yasuhiro Matsumura; Kazuto Nishio; Kazunori Kataoka
Differential gene expression profile between PC-14 cells treated with free cisplatin and cisplatin-incorporated polymeric micelles.
Bioconjugate chemistry 2003;14(2):449-57.
2003: Eduardo Jule; Yukio Nagasaki; Kazunori Kataoka
Lactose-installed poly(ethylene glycol)-poly(d,l-lactide) block copolymer micelles exhibit fast-rate binding and high affinity toward a protein bed simulating a cell surface. A surface plasmon resonance study.
Bioconjugate chemistry 2003;14(1):177-86.
2003: Nobuhiro Nishiyama; Hendrik R Stapert; Guo-Dong Zhang; Daisuke Takasu; Dong-Lin Jiang; Tetsuo Nagano; Takuzo Aida; Kazunori Kataoka
Light-harvesting ionic dendrimer porphyrins as new photosensitizers for photodynamic therapy.
Bioconjugate chemistry 2003;14(1):58-66.
2002: Yuji Yamamoto; Kenji Yasugi; Atsushi Harada; Yukio Nagasaki; Kazunori Kataoka
Temperature-related change in the properties relevant to drug delivery of poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles in aqueous milieu.
Journal of controlled release : official journal of the Controlled Release Society 2002;82(2-3):359-71.
2002: Keiji Itaka; Atsushi Harada; Kozo Nakamura; Hiroshi Kawaguchi; Kazunori Kataoka
Evaluation by fluorescence resonance energy transfer of the stability of nonviral gene delivery vectors under physiological conditions.
Biomacromolecules 2002;3(4):841-5.
2002: Yoshinori Kakizawa; Kazunori Kataoka
Block copolymer micelles for delivery of gene and related compounds.
Advanced drug delivery reviews 2002;54(2):203-22.
2001: Yuji Yamamoto; Yukio Nagasaki; Yukio Kato; Yuichi Sugiyama; Kazunori Kataoka
Long-circulating poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles with modulated surface charge.
Journal of controlled release : official journal of the Controlled Release Society 2001;77(1-2):27-38.
2001: Hidenori Otsuka; Y Akiyama; Yukio Nagasaki; Kazunori Kataoka
Quantitative and reversible lectin-induced association of gold nanoparticles modified with alpha-lactosyl-omega-mercapto-poly(ethylene glycol).
Journal of the American Chemical Society 2001;123(34):8226-30.
2001: Nobuhiro Nishiyama; Kazunori Kataoka
Preparation and characterization of size-controlled polymeric micelle containing cis-dichlorodiammineplatinum(II) in the core.
Journal of controlled release : official journal of the Controlled Release Society 2001;74(1-3):83-94.
2001: Nobuhiro Nishiyama; Yukio Kato; Yuichi Sugiyama; Kazunori Kataoka
Cisplatin-loaded polymer-metal complex micelle with time-modulated decaying property as a novel drug delivery system.
Pharmaceutical research 2001;18(7):1035-41.
2001: Atsushi Harada; Kazunori Kataoka
Pronounced activity of enzymes through the incorporation into the core of polyion complex micelles made from charged block copolymers.
Journal of controlled release : official journal of the Controlled Release Society 2001;72(1-3):85-91.
2001: Atsushi Harada; H Togawa; Kazunori Kataoka
Physicochemical properties and nuclease resistance of antisense-oligodeoxynucleotides entrapped in the core of polyion complex micelles composed of poly(ethylene glycol)-poly(L-lysine) block copolymers.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2001;13(1):35-42.
2001: Kazunori Kataoka; Atsushi Harada; Yukio Nagasaki
Block copolymer micelles for drug delivery: design, characterization and biological significance.
Advanced drug delivery reviews 2001;47(1):113-31.
2001: E Uchimura; Hidenori Otsuka; Teruo Okano; Y Sakurai; Kazunori Kataoka
Totally synthetic polymer with lectin-like function: induction of killer cells by the copolymer of 3-acrylamidophenylboronic acid with N,N-dimethylacrylamide.
Biotechnology and bioengineering 2001;72(3):307-14.
2001: Yukio Nagasaki; Kenji Yasugi; Yuji Yamamoto; Atsushi Harada; Kazunori Kataoka
Sugar-installed block copolymer micelles: their preparation and specific interaction with lectin molecules.
Biomacromolecules 2001;2(4):1067-70.
2001: Yoshinori Kakizawa; Atsushi Harada; Kazunori Kataoka
Glutathione-sensitive stabilization of block copolymer micelles composed of antisense DNA and thiolated poly(ethylene glycol)-block-poly(L-lysine): a potential carrier for systemic delivery of antisense DNA.
Biomacromolecules 2001;2(2):491-7.
2000: Kazunori Kataoka; T Matsumoto; M Yokoyama; Teruo Okano; Y Sakurai; Shigeto Fukushima; K Okamoto; G S Kwon
Doxorubicin-loaded poly(ethylene glycol)-poly(beta-benzyl-L-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance.
Journal of controlled release : official journal of the Controlled Release Society 2000;64(1-3):143-53.
2000: Hidenori Otsuka; Yukio Nagasaki; Kazunori Kataoka
Surface characterization of functionalized polylactide through the coating with heterobifunctional poly(ethylene glycol)/polylactide block copolymers.
Biomacromolecules 2000;1(1):39-48.
1999: Kenji Yasugi; Yukio Nagasaki; M Kato; Kazunori Kataoka
Preparation and characterization of polymer micelles from poly(ethylene glycol)-poly(D,L-lactide) block copolymers as potential drug carrier.
Journal of controlled release : official journal of the Controlled Release Society 1999;62(1-2):89-100.
1999: M Yokoyama; Teruo Okano; Y Sakurai; S Fukushima; K Okamoto; Kazunori Kataoka
Selective delivery of adriamycin to a solid tumor using a polymeric micelle carrier system.
Journal of drug targeting 1999;7(3):171-86.
1998: M Yokoyama; A Satoh; Y Sakurai; Teruo Okano; Y Matsumura; T Kakizoe; Kazunori Kataoka
Incorporation of water-insoluble anticancer drug into polymeric micelles and control of their particle size.
Journal of controlled release : official journal of the Controlled Release Society 1998;55(2-3):219-29.
1998: Kazunori Kataoka
[Intracellular gene delivery by polymer micelle vectors].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(3):718-23.
1998: Tetsuya Nakamura; Yukio Nagasaki; Kazunori Kataoka
Synthesis of heterobifunctional poly(ethylene glycol) with a reducing monosaccharide residue at one end.
Bioconjugate chemistry 1998;9(2):300-3.
1998: S Katayose; Kazunori Kataoka
Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethylene glycol)-poly(L-lysine) block copolymer.
Journal of pharmaceutical sciences 1998;87(2):160-3.
1998: M Yokoyama; S Fukushima; R Uehara; K Okamoto; Kazunori Kataoka; Y Sakurai; Teruo Okano
Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor.
Journal of controlled release : official journal of the Controlled Release Society 1998;50(1-3):79-92.
1998: Kazunori Kataoka; Hiroshi Ito; H Amano; Y Nagasaki; M Kato; Toshihisa Tsuruta; K Suzuki; Teruo Okano; Y Sakurai
Minimized platelet interaction with poly(2-hydroxyethyl methacrylate-block-4-bis(trimethylsilyl)methylstyrene) hydrogel showing anomalously high free water content.
Journal of biomaterials science. Polymer edition 1998;9(2):111-29.
1997: S Katayose; Kazunori Kataoka
Water-soluble polyion complex associates of DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer.
Bioconjugate chemistry 1997;8(5):702-7.
1997: I Hisamitsu; Kazunori Kataoka; T Okano; Y Sakurai
Glucose-responsive gel from phenylborate polymer and poly(vinyl alcohol): prompt response at physiological pH through the interaction of borate with amino group in the gel.
Pharmaceutical research 1997;14(3):289-93.
1997: T Aoki; Y Nagao; K Sanui; N Ogata; Akihiko Kikuchi; Y Sakurai; Kazunori Kataoka; Teruo Okano
Effect of phenylboronic acid groups in copolymers on endothelial cell differentiation into capillary structures.
Journal of biomaterials science. Polymer edition 1997;9(1):1-14.
1996: Akihiko Kikuchi; K Suzuki; O Okabayashi; H Hoshino; Kazunori Kataoka; Y Sakurai; Teruo Okano
Glucose-sensing electrode coated with polymer complex gel containing phenylboronic Acid.
Analytical chemistry 1996;68(5):823-8.
1996: A Kikuchi; H Taira; T Tsuruta; M Hayashi; Kazunori Kataoka
Adsorbed serum protein mediated adhesion and growth behavior of bovine aortic endothelial cells on polyamine graft copolymer surfaces.
Journal of biomaterials science. Polymer edition 1996;8(2):77-90.
1995: Y Nagasaki; M Iijima; M Kato; Kazunori Kataoka
Primary amino-terminal heterobifunctional poly(ethylene oxide). Facile synthesis of poly(ethylene oxide) with a primary amino group at one end and a hydroxyl group at the other end.
Bioconjugate chemistry 1995;6(6):702-4.
1995: Y Nagasaki; T Kutsuna; M Iijima; M Kato; Kazunori Kataoka; S Kitano; Y Kadoma
Formyl-ended heterobifunctional poly(ethylene oxide): synthesis of poly(ethylene oxide) with a formyl group at one end and a hydroxyl group at the other end.
Bioconjugate chemistry 1995;6(2):231-3.
1995: S Cammas; Y Nagasaki; Kazunori Kataoka
Heterobifunctional poly(ethylene oxide): synthesis of alpha-methoxy-omega-amino and alpha-hydroxy-omega-amino PEOs with the same molecular weights.
Bioconjugate chemistry 1995;6(2):226-30.
1995: T Aoki; Y Nagao; E Terada; K Sanui; N Ogata; N Yamada; Y Sakurai; Kazunori Kataoka; Teruo Okano
Endothelial cell differentiation into capillary structures by copolymer surfaces with phenylboronic acid groups.
Journal of biomaterials science. Polymer edition 1995;7(7):539-50.
1992: M Yokoyama; G S Kwon; T Okano; Y Sakurai; T Seto; Kazunori Kataoka
Preparation of micelle-forming polymer-drug conjugates.
Bioconjugate chemistry 1992;3(4):295-301.
1992: M Yokoyama; T Okano; Y Sakurai; A Kikuchi; N Ohsako; Y Nagasaki; Kazunori Kataoka
Synthesis of poly(ethylene oxide) with heterobifunctional reactive groups at its terminals by an anionic initiator.
Bioconjugate chemistry 1992;3(4):275-6.
1992: A Kikuchi; Kazunori Kataoka; T Tsuruta
Adhesion and proliferation of bovine aortic endothelial cells on monoamine- and diamine-containing polystyrene derivatives.
Journal of biomaterials science. Polymer edition 1992;3(3):253-60.
1992: A Kikuchi; Kazunori Kataoka; T Tsuruta
The role of protonation and conformational transition of polyamine grafts in platelet retention to polyamine-graft-PHEMA copolymer surfaces.
Journal of biomaterials science. Polymer edition 1992;3(5):355-74.
1991: M Yokoyama; Teruo Okano; Y Sakurai; H Ekimoto; C Shibazaki; Kazunori Kataoka
Toxicity and antitumor activity against solid tumors of micelle-forming polymeric anticancer drug and its extremely long circulation in blood.
Cancer research 1991;51(12):3229-36.
1990: M Yokoyama; M Miyauchi; N Yamada; Teruo Okano; Y Sakurai; Kazunori Kataoka; S Inoue
Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer.
Cancer research 1990;50(6):1693-700.
1989: A Maruyama; T Tsuruta; Kazunori Kataoka; Y Sakurai
Separation of B and T lymphocytes by cellular adsorption chromatography with polyamine graft copolymers as column matrices. II. Recovery of adsorbed B cell enriched populations from the column.
Biomaterials 1989;10(6):393-9.
1989: N Yui; Kazunori Kataoka; Y Sakurai; Y Fujishima; T Aoki; A Maruyama; K Sanui; N Ogata
Change in cytoplasmic free Ca2+ concentration in rabbit platelets contacting with albumin coated and uncoated polystyrene surfaces.
Biomaterials 1989;10(5):309-12.
1989: A Maruyama; T Tsuruta; Kazunori Kataoka; Y Sakurai
Elimination of cellular active adhesion on microdomain-structured surface of graft-polyamine copolymers.
Biomaterials 1989;10(5):291-8.
1989: Y Nabeshima; T Tsuruta; Kazunori Kataoka; Y Sakurai
Structural control of poly(2-hydroxyethyl methacrylate)-graft-polyamine copolymers for differential retention of rat lymphocyte subpopulations.
Journal of biomaterials science. Polymer edition 1989;1(2):85-97.
1988: Kazunori Kataoka
Molecular design of materials for cell separation.
Artificial organs 1988;12(6):511-3.
1988: A Maruyama; T Tsuruta; Kazunori Kataoka; Y Sakurai
Quantitative evaluation of rat lymphocyte adsorption on microdomain structured surfaces of poly(2-hydroxyethyl methacrylate)/polyamine.
Biomaterials 1988;9(6):471-81.
1988: A Maruyama; T Tsuruta; Kazunori Kataoka; Y Sakurai
Separation of B- and T-lymphocytes by cellular adsorption chromatography using poly(2-hydroxyethyl methacrylate)/polyamine graft copolymer as column adsorbent.
Journal of biomedical materials research 1988;22(6):555-71.
1988: N Yui; Kazunori Kataoka; Y Sakurai; T Aoki; K Sanui; N Ogata
In vitro and in vivo studies on antithrombogenicity of poly(propylene oxide) segmented nylon 610 in relation to its crystalline-amorphous microstructure.
Biomaterials 1988;9(3):225-9.
1988: Kazunori Kataoka; Y Sakurai; T Hanai; A Maruyama; T Tsuruta
Immunoaffinity chromatography of lymphocyte subpopulations using tert-amine derived matrices with adsorbed antibodies.
Biomaterials 1988;9(3):218-24.
1986: N Yui; K Sanui; N Ogata; Kazunori Kataoka; Teruo Okano; Y Sakurai
Effect of microstructure of poly(propylene-oxide)-segmented polyamides on platelet adhesion.
Journal of biomedical materials research 1986;20(7):929-43.
1985: N Yui; K Sanui; N Ogata; Kazunori Kataoka; Teruo Okano; Y Sakurai
Reversibility of granulocyte adhesion using polyamine-grafted nylon-6 as a new column substrate for granulocyte separation.
Biomaterials 1985;6(6):409-15.
1983: N Yui; K Sanui; N Ogata; Kazunori Kataoka; Teruo Okano; Y Sakurai
Effect of crystallinity of polyamides on adhesion-separation behavior of granulocytes.
Journal of biomedical materials research 1983;17(2):383-8.