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Shigeaki Kato

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Yoko Yamamoto; Tatsuya Yoshizawa; Taiyong Yu; Ken-Ichi Aihara; Pierre Chambon; Toru Fukuda; Maiko Hoshino; Erina Inoue; Kazuki Inoue; Gerard Karsenty; Shigeaki Kato; Hirotaka Kawano; Daniel Metzger; Yuko Nakamichi; Takashi Sato; Keisuke Sekine; Masayo Shindo; Yuko Shirode-Fukuda; Naoya Tsuji; Tomoyuki Watanabe; Yuuki Imai
Vitamin D receptor in osteoblasts is a negative regulator of bone mass control.
Mina Kozai; Masashi Masuda; Otoki Nakahashi; Ayako Otani; Nagakatsu Harada; Shoko Ikeda; Mariko Ishiguro; Tomohiro Kagawa; Shigeaki Kato; Yuichiro Takei; Yutaka Taketani; Ken-Ichi Takeyama; Hironori Yamamoto; Eiji Takeda
Thyroid hormones decrease plasma 1α,25-dihydroxyvitamin D levels through transcriptional repression of the renal 25-hydroxyvitamin D3 1α-hydroxylase gene (CYP27B1).
Takahiro Matsumoto; Maiko Okada; Matomo Sakari; Sayuri Takahashi; Atsushi Yokoyama; Alexander Kouzmenko; Shigeaki Kato
The androgen receptor in health and disease.

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All Publications

2013: Yoko Yamamoto; Tatsuya Yoshizawa; Taiyong Yu; Ken-Ichi Aihara; Pierre Chambon; Toru Fukuda; Maiko Hoshino; Erina Inoue; Kazuki Inoue; Gerard Karsenty; Shigeaki Kato; Hirotaka Kawano; Daniel Metzger; Yuko Nakamichi; Takashi Sato; Keisuke Sekine; Masayo Shindo; Yuko Shirode-Fukuda; Naoya Tsuji; Tomoyuki Watanabe; Yuuki Imai
Vitamin D receptor in osteoblasts is a negative regulator of bone mass control.
Endocrinology 2013;154(3):1008-20.
2013: Mina Kozai; Masashi Masuda; Otoki Nakahashi; Ayako Otani; Nagakatsu Harada; Shoko Ikeda; Mariko Ishiguro; Tomohiro Kagawa; Shigeaki Kato; Yuichiro Takei; Yutaka Taketani; Ken-Ichi Takeyama; Hironori Yamamoto; Eiji Takeda
Thyroid hormones decrease plasma 1α,25-dihydroxyvitamin D levels through transcriptional repression of the renal 25-hydroxyvitamin D3 1α-hydroxylase gene (CYP27B1).
Endocrinology 2013;154(2):609-22.
2013: Takahiro Matsumoto; Maiko Okada; Matomo Sakari; Sayuri Takahashi; Atsushi Yokoyama; Alexander Kouzmenko; Shigeaki Kato
The androgen receptor in health and disease.
Annual review of physiology 2013;75():201-24.
2012: Masahiro Shinohara; Sakae Tanaka; Kohjiro Ueki; Jun Hirose; Mitsuyasu Iwasawa; Yuho Kadono; Takashi Kadowaki; Shigeaki Kato; Hironari Masuda; Yuuichi Nagase; Hiroaki Nakamura; Masaki Nakamura; Takehiko Sasaki; Hiroshi Takayanagi
Class IA phosphatidylinositol 3-kinase regulates osteoclastic bone resorption through protein kinase B-mediated vesicle transport.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2012;27(12):2464-75.
2012: Noriyuki Aoi; Toshihiro Chikanishi; Kentaro Doi; Hitomi Eto; Ryoji Fujiki; Keita Inoue; Satoshi Itami; Harunosuke Kato; Shigeaki Kato; Hanako Yamamoto; Kotaro Yoshimura
1α,25-dihydroxyvitamin D3 modulates the hair-inductive capacity of dermal papilla cells: therapeutic potential for hair regeneration.
Stem cells translational medicine 2012;1(8):615-26.
2012: Mi-Sun Kim; Hirochika Kitagawa; Takeshi Kondo; Takahiro Matsumoto; Fumiaki Ohtake; Hiroshi Shibuya; Yuko Shirode; Ichiro Takada; Sayuri Takahashi; Ken-Ichi Takeyama; Yoko Yamamoto; Ikuko Yamaoka; Min-Young Youn; Sally Fujiyama; Shigeaki Kato
Retraction: DNA demethylation in hormone-induced transcriptional derepression.
Nature 2012;486(7402):280.
2012: Yuki Kamoshida; Shigeaki Kato; Shuhei Kimura; Jinseon Lim; Yumi Shiozaki-Sato; Eriko Suzuki; Sally Fujiyama-Nakamura; Ken-Ichi Takeyama
Ecdysone receptor (EcR) suppresses lipid accumulation in the Drosophila fat body via transcription control.
Biochemical and biophysical research communications 2012;421(2):203-7.
2012: Min Young Youn; Shigeaki Kato; Yuuki Imai
[Epigenetic regulation during osteoclastogenesis].
Clinical calcium 2012;22(5):611-7.
2012: Min-Young Youn; Sally Fujiyama-Nakamura; Shigeaki Kato; Ken-ichi Minehata; Fumiaki Ohtake; Takeshi Suzuki; Hisataka Yasuda; Atsushi Yokoyama; Yuuki Imai
JMJD5, a Jumonji C (JmjC) domain-containing protein, negatively regulates osteoclastogenesis by facilitating NFATc1 protein degradation.
The Journal of biological chemistry 2012;287(16):12994-3004.
2012: Koji Fujita; Toru Fukuda; Hiroshi Itoh; Makiko Iwasaki; Shigeaki Kato; Tatsuhiko Kodama; Chengshan Ma; Takeshi Miyamoto; Takako Negishi-Koga; Hiroki Ochi; Atsushi Okawa; Kenichi Shinomiya; Satoko Sunamura; Hiroshi Takayanagi; Kimitaka Takitani; Hiroshi Tamai; Hiroyuki Arai; Shu Takeda
Vitamin E decreases bone mass by stimulating osteoclast fusion.
Nature medicine 2012;18(4):589-94.
2012: Saya Ito; Yuki Kamoshida; Hiromi Kato; Ryoji Fujiki; Sally Fujiyama-Nakamura; Shuhei Kimura; Alexander Kouzmenko; Jinseon Lim; Tsuneharu Miki; Takuya Murata; Fumiaki Ohtake; Shun Sawatsubashi; Yumi Shiozaki-Sato; Eriko Suzuki; Ken-Ichi Takeyama; Masahiko Tanabe; Takashi Ueda; Shigeaki Kato
Epigenetic silencing of core histone genes by HERS in Drosophila.
Molecular cell 2012;45(4):494-504.
2012: Kaori Tsuji-Takechi; Shigeaki Kato; Akiko Kukita; Takahiro Maeda; Keiji Moriyama; Takako Negishi-Koga; Pier Paolo Pandolfi; Eriko Sumiya; Hiroshi Takayanagi
Stage-specific functions of leukemia/lymphoma-related factor (LRF) in the transcriptional control of osteoclast development.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(7):2561-6.
2012: Ichiro Takada; Yoshiko Yogiashi; Shigeaki Kato
Signaling Crosstalk between PPARγ and BMP2 in Mesenchymal Stem Cells.
PPAR research 2012;2012():607141.
2011: Shigeaki Kato
[Bone and calcium update; bone research update. Role of steroid hormones in regulation of the epigenesis].
Clinical calcium 2011;21(12):78-84.
2011: Shigeaki Kato; Yoko Yamamoto
[Frontiers in vitamin D; basic research and clinical application. Is VDR a factor of bone volume regulator in bone tissues?].
Clinical calcium 2011;21(11):45-52.
2011: Fumiaki Ohtake; Kaname Kawajiri; Yoshiaki Fujii-Kuriyama; Shigeaki Kato
Cross-talk of dioxin and estrogen receptor signals through the ubiquitin system.
The Journal of steroid biochemistry and molecular biology 2011;127(1-2):102-7.
2011: Atsushi Yokoyama; Shogo Katsura; Hiroki Sekine; Ryoji Fujiki; Waka Hashiba; Ryo Ito; Shigeaki Kato
Multiple post-translational modifications in hepatocyte nuclear factor 4α.
Biochemical and biophysical research communications 2011;410(4):749-53.
2011: Yuuki Imai; Shigeaki Kato
[Function of sex steroid hormone receptors in bone metabolism].
Nihon rinsho. Japanese journal of clinical medicine 2011;69(7):1198-202.
2011: Atsushi Baba; Fumiaki Ohtake; Yosuke Okuno; Kenichi Yokota; Maiko Okada; Yuuki Imai; Min Ni; Clifford A Meyer; Katsuhide Igarashi; Jun Kanno; Myles Brown; Shigeaki Kato
PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B.
Nature cell biology 2011;13(6):668-75.
2011: Shigeaki Kato; Atsushi Yokoyama; Ryoji Fujiki
Nuclear receptor coregulators merge transcriptional coregulation with epigenetic regulation.
Trends in biochemical sciences 2011;36(5):272-81.
2011: M Tanikawa; Osamu Wada-Hiraike; Shunsuke Nakagawa; A Shirane; H Hiraike; S Koyama; Yusei Miyamoto; K Sone; T Tsuruga; Kenji Nagasaka; Yoshitsugu Matsumoto; Yasuo Ikeda; K Shoji; Kohei Oda; Hiroshi Fukuhara; Keiichi Nakagawa; Shigeaki Kato; Tetsu Yano; Yuji Taketani
Multifunctional transcription factor TFII-I is an activator of BRCA1 function.
British journal of cancer 2011;104(8):1349-55.
2011: Sayuri Takahashi; Tomoyuki Watanabe; Maiko Okada; Kazuki Inoue; Takashi Ueda; Ichiro Takada; Tetsuro Watabe; Yoko Yamamoto; Toru Fukuda; Takashi Nakamura; Chihiro Akimoto; Tetsuya Fujimura; Maiko Hoshino; Yuuki Imai; Daniel Metzger; Kohei Miyazono; Yasuhiro Minami; Pierre Chambon; Tadaichi Kitamura; Takahiro Matsumoto; Shigeaki Kato
Noncanonical Wnt signaling mediates androgen-dependent tumor growth in a mouse model of prostate cancer.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(12):4938-43.
2011: Atsushi Sato; Jun Ooi; Shuji Takahashi; Nobuhiro Tsukada; Shigeaki Kato; T Kawakita; T Yagyu; Fumitaka Nagamura; Tohru Iseki; Arinobu Tojo; Shigetaka Asano
Unrelated cord blood transplantation after myeloablative conditioning in adults with advanced myelodysplastic syndromes.
Bone marrow transplantation 2011;46(2):257-61.
2011: A Yokoyama; Fumiaki Ohtake; Ryoji Fujiki; Shigeaki Kato
Regulated histone methyltransferase and demethylase complexes in the control of genes by nuclear receptors.
Cold Spring Harbor symposia on quantitative biology 2011;76():165-73.
2011: Shigeaki Kato; Ryoji Fujiki
Transcriptional controls by nuclear fat-soluble vitamin receptors through chromatin reorganization.
Bioscience, biotechnology, and biochemistry 2011;75(3):410-3.
2011: Ken-ichi Takeyama; Shigeaki Kato
The vitamin D3 1alpha-hydroxylase gene and its regulation by active vitamin D3.
Bioscience, biotechnology, and biochemistry 2011;75(2):208-13.
2011: Hirochika Kitagawa; Ryoji Fujiki; Kimihiro Yoshimura; Hiroyuki Oya; Shigeaki Kato
Williams syndrome is an epigenome-regulator disease.
Endocrine journal 2011;58(2):77-85.
2010: Alexander Kouzmenko; Fumiaki Ohtake; Ryoji Fujiki; Shigeaki Kato
Hormonal gene regulation through DNA methylation and demethylation.
Epigenomics 2010;2(6):765-74.
2010: Chihiro Akimoto; Takashi Ueda; Kazuki Inoue; Ikuko Yamaoka; Matomo Sakari; Wataru Obara; Tomoaki Fujioka; Akira Nagahara; Norio Nonomura; Syuichi Tsutsumi; Hiroyuki Aburatani; Tsuneharu Miki; Takahiro Matsumoto; Hirochika Kitagawa; Shigeaki Kato
Testis-specific protein on Y chromosome (TSPY) represses the activity of the androgen receptor in androgen-dependent testicular germ-cell tumors.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(46):19891-6.
2010: Shigeaki Kato
[Synthetic ligands for nuclear receptors].
Nihon rinsho. Japanese journal of clinical medicine 2010;68(10):1830-4.
2010: Atsushi Yokoyama; Yosuke Okuno; Toshihiro Chikanishi; Waka Hashiba; Hiroki Sekine; Ryoji Fujiki; Shigeaki Kato
KIAA1718 is a histone demethylase that erases repressive histone methyl marks.
Genes to cells : devoted to molecular & cellular mechanisms 2010;15(8):867-73.
2010: Eiji Ochiai; Hirochika Kitagawa; Ichiro Takada; Sally Fujiyama; Shun Sawatsubashi; Mi-sun Kim; Yoshihiro Mezaki; Yu Tsushima; Ken-ichiro Takagi; Yoshiaki Azuma; Ken-ichi Takeyama; Kazuyoshi Yamaoka; Shigeaki Kato; TAKASHI KAMIMURA
CDP/cut is an osteoblastic coactivator of the vitamin D receptor (VDR).
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(5):1157-66.
2010: Toshihiro Chikanishi; Ryoji Fujiki; Waka Hashiba; Hiroki Sekine; Atsushi Yokoyama; Shigeaki Kato
Glucose-induced expression of MIP-1 genes requires O-GlcNAc transferase in monocytes.
Biochemical and biophysical research communications 2010;394(4):865-70.
2010: Jing Yu; Masahiro Akishita; Masato Eto; Sumito Ogawa; Bo-Kyung Son; Shigeaki Kato; Yasuyoshi Ouchi; Tetsuro Okabe
Androgen receptor-dependent activation of endothelial nitric oxide synthase in vascular endothelial cells: role of phosphatidylinositol 3-kinase/akt pathway.
Endocrinology 2010;151(4):1822-8.
2010: Fumitaka Mizoguchi; Yayoi Izu; Tadayoshi Hayata; Hiroaki Hemmi; Kazuhisa Nakashima; Takashi Nakamura; Shigeaki Kato; Nobuyuki Miyasaka; Yoichi Ezura; Masaki Noda
Osteoclast-specific Dicer gene deficiency suppresses osteoclastic bone resorption.
Journal of cellular biochemistry 2010;109(5):866-75.
2010: H Hiraike; Osamu Wada-Hiraike; Shunsuke Nakagawa; S Koyama; Yusei Miyamoto; K Sone; M Tanikawa; T Tsuruga; Kenji Nagasaka; Yoshitsugu Matsumoto; Katsutoshi Oda; K Shoji; Hiroshi Fukuhara; S Saji; Keiichi Nakagawa; Shigeaki Kato; Tetsu Yano; Yuji Taketani
Identification of DBC1 as a transcriptional repressor for BRCA1.
British journal of cancer 2010;102(6):1061-7.
2010: Ichiro Takada; Naoya Tsuji; Min-Young Youn; Sally Fujiyama; Maiko Okada; Yuuki Imai; Shino Kondo; Hirochika Kitakawa; Hisataka Yasuda; Shigeaki Kato
Purification and identification of estrogen receptor alpha co-regulators in osteoclasts.
Annals of the New York Academy of Sciences 2010;1192():201-7.
2010: Yuuki Imai; Shigeaki Kato
[Effects of SERMs on bone health. Mechanisms of bone mass control by selective estrogen receptor modulator].
Clinical calcium 2010;20(3):339-44.
2010: Keizo Nishikawa; Tomoki Nakashima; Mikihito Hayashi; Takanobu Fukunaga; Shigeaki Kato; Tatsuhiko Kodama; Satoru Takahashi; Kathryn Calame; Hiroshi Takayanagi
Blimp1-mediated repression of negative regulators is required for osteoclast differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(7):3117-22.
2010: Satoshi Koyama; Osamu Wada-Hiraike; Shunsuke Nakagawa; Michihiro Tanikawa; Haruko Hiraike; Yuichiro Miyamoto; Kenbun Sone; Katsutoshi Oda; Hiroshi Fukuhara; Keiichi Nakagawa; Shigeaki Kato; Tetsu Yano; Yuji Taketani
Repression of estrogen receptor beta function by putative tumor suppressor DBC1.
Biochemical and biophysical research communications 2010;392(3):357-62.
2010: Shigeaki Kato; Ichiro Takada
[Structural insights of PPARgamma].
Nihon rinsho. Japanese journal of clinical medicine 2010;68(2):176-9.
2010: Shigeaki Kato; Yuuki Imai
[Bone and Men's Health. Function of androgen receptor in bone tissues].
Clinical calcium 2010;20(2):198-203.
2010: Shun Sawatsubashi; Takuya Murata; Jinseon Lim; Ryoji Fujiki; Saya Ito; Eriko Suzuki; Masahiko Tanabe; Yue Zhao; Shuhei Kimura; Sally Fujiyama; Takashi Ueda; Daiki Umetsu; Takashi Ito; Ken-ichi Takeyama; Shigeaki Kato
A histone chaperone, DEK, transcriptionally coactivates a nuclear receptor.
Genes & development 2010;24(2):159-70.
2010: Sally Fujiyama-Nakamura; Kaoru Yamagata; Shigeaki Kato
Hormonal repression of miRNA biosynthesis through a nuclear steroid hormone receptor.
Advances in experimental medicine and biology 2010;700():43-55.
2009: Yuuki Imai; Shino Kondoh; Alexander Kouzmenko; Shigeaki Kato
Regulation of bone metabolism by nuclear receptors.
Molecular and cellular endocrinology 2009;310(1-2):3-10.
2009: Kaoru Yamagata; Sally Fujiyama; Saya Ito; Takashi Ueda; Takuya Murata; Masanori Naitou; Ken-Ichi Takeyama; Yasuhiro Minami; Bert W O'Malley; Shigeaki Kato
Maturation of microRNA is hormonally regulated by a nuclear receptor.
Molecular cell 2009;36(2):340-7.
2009: Mi-Sun Kim; Takeshi Kondo; Ichiro Takada; Min-Young Youn; Yoko Yamamoto; Sayuri Takahashi; Takahiro Matsumoto; Sally Fujiyama; Yuko Shirode; Ikuko Yamaoka; Hirochika Kitagawa; Ken-ichi Takeyama; Hiroshi Shibuya; Fumiaki Ohtake; Shigeaki Kato
DNA demethylation in hormone-induced transcriptional derepression.
Nature 2009;461(7266):1007-12.
2009: Yuuki Imai; Ming-Young Youn; Shino Kondoh; Takashi Nakamura; Alexander Kouzmenko; Takahiro Matsumoto; Ichiro Takada; Kunio Takaoka; Shigeaki Kato
Estrogens maintain bone mass by regulating expression of genes controlling function and life span in mature osteoclasts.
Annals of the New York Academy of Sciences 2009;1173 Suppl 1():E31-9.
2009: Sally Fujiyama-Nakamura; Saya Ito; Shun Sawatsubashi; Yoshio Yamauchi; Eriko Suzuki; Masahiko Tanabe; Shuhei Kimura; Takuya Murata; Toshiaki Isobe; Ken-ichi Takeyama; Shigeaki Kato
BTB protein, dKLHL18/CG3571, serves as an adaptor subunit for a dCul3 ubiquitin ligase complex.
Genes to cells : devoted to molecular & cellular mechanisms 2009;14(8):965-73.
2009: Ichiro Takada; Alexander P Kouzmenko; Shigeaki Kato
Wnt and PPARgamma signaling in osteoblastogenesis and adipogenesis.
Nature reviews. Rheumatology 2009;5(8):442-7.
2009: Hiroshi I Suzuki; Kaoru Yamagata; Koichi Sugimoto; Takashi Iwamoto; Shigeaki Kato; Kohei Miyazono
Modulation of microRNA processing by p53.
Nature 2009;460(7254):529-33.
2009: Shigeaki Kato
[Hormones and osteoporosis update. Androgen and bone remodeling].
Clinical calcium 2009;19(7):957-62.
2009: Shigeaki Kato
[Hormones and osteoporosis update. Estrogen and bone remodeling].
Clinical calcium 2009;19(7):951-6.
2009: Kimihiro Yoshimura; Hirochika Kitagawa; Ryoji Fujiki; Masahiko Tanabe; Shinichiro Takezawa; Ichiro Takada; Ikuko Yamaoka; Masayoshi Yonezawa; Takeshi Kondo; Yoshiyuki Furutani; Hisato Yagi; Shin Yoshinaga; Takeyoshi Masuda; Toru Fukuda; Yoko Yamamoto; Kanae Ebihara; Dean Y Li; Rumiko Matsuoka; Jun K Takeuchi; Takahiro Matsumoto; Shigeaki Kato
Distinct function of 2 chromatin remodeling complexes that share a common subunit, Williams syndrome transcription factor (WSTF).
Proceedings of the National Academy of Sciences of the United States of America 2009;106(23):9280-5.
2009: Eriko Suzuki; Yue Zhao; Saya Ito; Shun Sawatsubashi; Takuya Murata; Takashi Furutani; Yuko Shirode; Kaoru Yamagata; Masahiko Tanabe; Shuhei Kimura; Takashi Ueda; Sally Fujiyama; Jinseon Lim; Hiroyuki Matsukawa; Alexander P Kouzmenko; Toshiro Aigaki; Tetsuya Tabata; Ken-ichi Takeyama; Shigeaki Kato
Aberrant E2F activation by polyglutamine expansion of androgen receptor in SBMA neurotoxicity.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(10):3818-22.
2009: Jun Ooi; Shuji Takahashi; Akira Tomonari; Nobuhiro Tsukada; Takaaki Konuma; Shigeaki Kato; S Kasahara; Atsushi Sato; F Monma; Fumitaka Nagamura; Tohru Iseki; Arinobu Tojo; Shigetaka Asano
Unrelated cord blood transplantation after myeloablative conditioning in adults with ALL.
Bone marrow transplantation 2009;43(6):455-9.
2009: Fumiaki Ohtake; Yoshiaki Fujii-Kuriyama; Shigeaki Kato
AhR acts as an E3 ubiquitin ligase to modulate steroid receptor functions.
Biochemical pharmacology 2009;77(4):474-84.
2009: Yue Zhao; Ken-ichi Takeyama; Shun Sawatsubashi; Saya Ito; Eriko Suzuki; Kaoru Yamagata; Masahiko Tanabe; Shuhei Kimura; Sally Fujiyama; Takashi Ueda; Takuya Murata; Hiroyuki Matsukawa; Yuko Shirode; Alexander Kouzmenko; Feng Li; Testuya Tabata; Shigeaki Kato
Corepressive action of CBP on androgen receptor transactivation in pericentric heterochromatin in a Drosophila experimental model system.
Molecular and cellular biology 2009;29(4):1017-34.
2008: Masahiko Tanabe; Alexander Kouzmenko; Saya Ito; Shun Sawatsubashi; Eriko Suzuki; Sally Fujiyama; Kaoru Yamagata; Yue Zhao; Shuhei Kimura; Takashi Ueda; Takuya Murata; Hiroyuki Matsukawa; Ken-ichi Takeyama; Shigeaki Kato
Activation of facultatively silenced Drosophila loci associates with increased acetylation of histone H2AvD.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(12):1279-88.
2008: Takuya Murata; Eriko Suzuki; Saya Ito; Shun Sawatsubashi; Yue Zhao; Kaoru Yamagata; Masahiko Tanabe; Sally Fujiyama; Shuhei Kimura; Takashi Ueda; Hiroyuki Matsukawa; Alexander Kouzmenko; Takashi Furutani; Erina Kuranaga; Masayuki Miura; Ken-ichi Takeyama; Shigeaki Kato
RNA-binding protein hoip accelerates polyQ-induced neurodegeneration in Drosophila.
Bioscience, biotechnology, and biochemistry 2008;72(9):2255-61.
2008: Alexander Kouzmenko; Ken-ichi Takeyama; Y Kawasaki; T Akiyama; Shigeaki Kato
Truncation mutations abolish chromatin-associated activities of adenomatous polyposis coli.
Oncogene 2008;27(36):4888-99.
2008: Shuhei Kimura; Shun Sawatsubashi; Saya Ito; Alexander Kouzmenko; Eriko Suzuki; Yue Zhao; Kaoru Yamagata; Masahiko Tanabe; Takashi Ueda; Sari Fujiyama; Takuya Murata; Hiroyuki Matsukawa; Ken-ichi Takeyama; Nobuo Yaegashi; Shigeaki Kato
Drosophila arginine methyltransferase 1 (DART1) is an ecdysone receptor co-repressor.
Biochemical and biophysical research communications 2008;371(4):889-93.
2008: Alexander P Kouzmenko; Ken-ichi Takeyama; Yoshihiro Kawasaki; Tetsu Akiyama; Shigeaki Kato
Ligand-dependent interaction between estrogen receptor alpha and adenomatous polyposis coli.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(7):723-30.
2008: Fumiaki Ohtake; Atsushi Baba; Yoshiaki Fujii-Kuriyama; Shigeaki Kato
Intrinsic AhR function underlies cross-talk of dioxins with sex hormone signalings.
Biochemical and biophysical research communications 2008;370(4):541-6.
2008: Chihiro Akimoto; Hirochika Kitagawa; Takahiro Matsumoto; Shigeaki Kato
Spermatogenesis-specific association of SMCY and MSH5.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(6):623-33.
2008: Maiko Okada; Shinichiro Takezawa; Yoshihiro Mezaki; Ikuko Yamaoka; Ichiro Takada; Hirochika Kitagawa; Shigeaki Kato
Switching of chromatin-remodelling complexes for oestrogen receptor-alpha.
EMBO reports 2008;9(6):563-8.
2008: Atsushi Yokoyama; Shinichiro Takezawa; Roland Schüle; Hirochika Kitagawa; Shigeaki Kato
Transrepressive function of TLX requires the histone demethylase LSD1.
Molecular and cellular biology 2008;28(12):3995-4003.
2008: Aya Iriyama; Ryoji Fujiki; Yuji Inoue; Hidenori Takahashi; Yasuhiro Tamaki; Shinichiro Takezawa; Ken-ichi Takeyama; woo-dong Jang; Shigeaki Kato; Yasuo Yanagi
A2E, a pigment of the lipofuscin of retinal pigment epithelial cells, is an endogenous ligand for retinoic acid receptor.
The Journal of biological chemistry 2008;283(18):11947-53.
2008: Lin Zhao; Michiko Watanabe; Tetsu Yano; Junn Yanagisawa; Shunsuke Nakagawa; Hajime Oishi; Osamu Wada-Hiraike; Katsutoshi Oda; Takeo Minaguchi; Toshiharu Yasugi; Shigeaki Kato; Yuji Taketani
Analysis of the status of the novel estrogen receptor α (ERα) coactivator p72 in endometrial cancer and its cross talk with erbB-2 in the transactivation of ERα.
Molecular medicine reports 2008;1(3):387-90.
2008: Ichiro Takada; Shigeaki Kato
[Molecular mechanism of switching adipocyte / osteoblast differentiation through regulation of PPAR-gamma function].
Clinical calcium 2008;18(5):656-61.
2008: Takahiro Matsumoto; Hiroko Shiina; Hirotaka Kawano; Takashi Sato; Shigeaki Kato
Androgen receptor functions in male and female physiology.
The Journal of steroid biochemistry and molecular biology 2008;109(3-5):236-41.
2008: Masataka Asagiri; Toshitake Hirai; Toshihiro Kunigami; Shunya Kamano; Hans-Jürgen Gober; Kazuo Okamoto; Keizo Nishikawa; Eicke Latz; Douglas T Golenbock; Kazuhiro Aoki; Keiichi Ohya; Yuuki Imai; Yasuyuki Morishita; Kohei Miyazono; Shigeaki Kato; Paul Saftig; Hiroshi Takayanagi
Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.
Science (New York, N.Y.) 2008;319(5863):624-7.
2008: Ken-ichi Takeyama; Shigeaki Kato
[Signal transduction mechanisms of steroid hormone receptors].
Nihon rinsho. Japanese journal of clinical medicine 2008;66(1):47-54.
2008: Shigeaki Kato; Ryoji Fujiki
[Molecular biology of nuclear steroid receptor].
Nihon rinsho. Japanese journal of clinical medicine 2008;66(1):2-6.
2007: Fumiaki Ohtake; Yoshiaki Fujii-Kuriyama; Shigeaki Kato
[Transcription factor AhR is a ligand-dependcnt E3 ubiquitin ligase].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2007;52(15):1973-9.
2007: Hirochika Kitagawa; Ikuko Yamaoka; Chihiro Akimoto; Ikuko Kase; Yoshihiro Mezaki; Takafumi Shimizu; Shigeaki Kato
A reduction state potentiates the glucocorticoid response through receptor protein stabilization.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(11):1281-7.
2007: Ichiro Takada; Masatomo Mihara; Miyuki Suzawa; Fumiaki Ohtake; Shinji Kobayashi; Mamoru Igarashi; Min-Young Youn; Ken-ichi Takeyama; Takashi Nakamura; Yoshihiro Mezaki; Shinichiro Takezawa; Yoshiko Yogiashi; Hirochika Kitagawa; Gen Yamada; Shinji Takada; Yasuhiro Minami; Hiroshi Shibuya; Kunihiro Matsumoto; Shigeaki Kato
A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation.
Nature cell biology 2007;9(11):1273-85.
2007: Mamoru Igarashi; Yoshiko Yogiashi; Masatomo Mihara; Ichiro Takada; Hirochika Kitagawa; Shigeaki Kato
Vitamin K induces osteoblast differentiation through pregnane X receptor-mediated transcriptional control of the Msx2 gene.
Molecular and cellular biology 2007;27(22):7947-54.
2007: Ichiro Takada; Miyuki Suzawa; Kunihiro Matsumoto; Shigeaki Kato
Suppression of PPAR transactivation switches cell fate of bone marrow stem cells from adipocytes into osteoblasts.
Annals of the New York Academy of Sciences 2007;1116():182-95.
2007: Shingo Sato; Reiko Hanada; Ayako Kimura; Tomomi Abe; Takahiro Matsumoto; Makiko Iwasaki; Hiroyuki Inose; Takanori Ida; Michihiro Mieda; Yasuhiro Takeuchi; Seiji Fukumoto; Toshiro Fujita; Shigeaki Kato; Kenji Kangawa; Masayasu Kojima; Kenichi Shinomiya; Shu Takeda
Central control of bone remodeling by neuromedin U.
Nature medicine 2007;13(10):1234-40.
2007: Takashi Nakamura; Yuuki Imai; Takahiro Matsumoto; Shingo Sato; Kazusane Takeuchi; Katsuhide Igarashi; Yoshifumi Harada; Yoshiaki Azuma; Andrée Krust; Yoko Yamamoto; Hiroshi Nishina; Shu Takeda; Hiroshi Takayanagi; Daniel Metzger; Jun Kanno; Kunio Takaoka; T John Martin; Pierre Chambon; Shigeaki Kato
Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts.
Cell 2007;130(5):811-23.
2007: A Memezawa; I Takada; K Takeyama; M Igarashi; S Ito; S Aiba; Shigeaki Kato; Alexander Kouzmenko
Id2 gene-targeted crosstalk between Wnt and retinoid signaling regulates proliferation in human keratinocytes.
Oncogene 2007;26(35):5038-45.
2007: Shigeaki Kato; Mi-sun Kim; Kazuyoshi Yamaoka; Ryoji Fujiki
Mechanisms of transcriptional repression by 1,25(OH)2 vitamin D.
Current opinion in nephrology and hypertension 2007;16(4):297-304.
2007: Junko Miyamoto; Takahiro Matsumoto; Hiroko Shiina; Kazuki Inoue; Ichiro Takada; Saya Ito; Johbu Itoh; Takeo Minematsu; Takashi Sato; Toshihiko Yanase; Hajime Nawata; Yoshiyuki Osamura; Shigeaki Kato
The pituitary function of androgen receptor constitutes a glucocorticoid production circuit.
Molecular and cellular biology 2007;27(13):4807-14.
2007: Shuhei Kimura; Takahiro Matsumoto; Reiko Matsuyama; Hiroko Shiina; Takashi Sato; Ken-ichi Takeyama; Shigeaki Kato
Androgen receptor function in folliculogenesis and its clinical implication in premature ovarian failure.
Trends in endocrinology and metabolism: TEM 2007;18(5):183-9.
2007: Toru Fukuda; Kaoru Yamagata; Sally Fujiyama; Takahiro Matsumoto; Iori Koshida; Kimihiro Yoshimura; Masatomo Mihara; Masanori Naitou; Hideki Endoh; Takashi Nakamura; Chihiro Akimoto; Yoko Yamamoto; Takenobu Katagiri; Charles Foulds; Shinichiro Takezawa; Hirochika Kitagawa; Ken-ichi Takeyama; Bert W O'Malley; Shigeaki Kato
DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs.
Nature cell biology 2007;9(5):604-11.
2007: Hiroaki Fuse; Shigeru Korenaga; Matomo Sakari; Takashi Hiyama; Takeshi Ito; Koichi Kimura; Shigeaki Kato
Non-steroidal antiandrogens act as AF-1 agonists under conditions of high androgen-receptor expression.
The Prostate 2007;67(6):630-7.
2007: Kazuyoshi Yamaoka; Masayo Shindo; Kei Iwasaki; Ikuko Yamaoka; Yoko Yamamoto; Hirochika Kitagawa; Shigeaki Kato
Multiple co-activator complexes support ligand-induced transactivation function of VDR.
Archives of biochemistry and biophysics 2007;460(2):166-71.
2007: Fumiaki Ohtake; Atsushi Baba; Ichiro Takada; Maiko Okada; Kei Iwasaki; Hiromi Miki; Sayuri Takahashi; Alexander Kouzmenko; Keiko Nohara; Tomoki Chiba; Yoshiaki Fujii-Kuriyama; Shigeaki Kato
Dioxin receptor is a ligand-dependent E3 ubiquitin ligase.
Nature 2007;446(7135):562-6.
2007: Shigeaki Kato; Ryoji Fujiki; Mi-Sun Kim; Hirochika Kitagawa
Ligand-induced transrepressive function of VDR requires a chromatin remodeling complex, WINAC.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):372-80.
2007: Shinichiro Takezawa; Atsushi Yokoyama; Maiko Okada; Ryoji Fujiki; Aya Iriyama; Yasuo Yanagi; Hiroaki Ito; Ichiro Takada; Masahiko Kishimoto; Atsushi Miyajima; Ken-ichi Takeyama; Kazuhiko Umesono; Hirochika Kitagawa; Shigeaki Kato
A cell cycle-dependent co-repressor mediates photoreceptor cell-specific nuclear receptor function.
The EMBO journal 2007;26(3):764-74.
2007: Hideo Mukai; Tomokazu Tsurugizawa; Gen Murakami; Shiro Kominami; Hirotaka Ishii; Mari Ogiue-Ikeda; Norio Takata; Nobuaki Tanabe; Aizo Furukawa; Yasushi Hojo; Yuuki Ooishi; John H Morrison; william janssen; John A Rose; Pierre Chambon; Shigeaki Kato; Shunsuke Izumi; Takeshi Yamazaki; Tetsuya Kimoto; Suguru Kawato
Rapid modulation of long-term depression and spinogenesis via synaptic estrogen receptors in hippocampal principal neurons.
Journal of neurochemistry 2007;100(4):950-67.
2007: Mi-Sun Kim; Ryoji Fujiki; Hirochika Kitagawa; Shigeaki Kato
1alpha,25(OH)2D3-induced DNA methylation suppresses the human CYP27B1 gene.
Molecular and cellular endocrinology 2007;265-266():168-73.
2007: Mi-sun Kim; Ryoji Fujiki; Akiko Murayama; Hirochika Kitagawa; Kazuyoshi Yamaoka; Yoko Yamamoto; Masatomo Mihara; Ken-ichi Takeyama; Shigeaki Kato
1Alpha,25(OH)2D3-induced transrepression by vitamin D receptor through E-box-type elements in the human parathyroid hormone gene promoter.
Molecular endocrinology (Baltimore, Md.) 2007;21(2):334-42.
2006: Yukiyo Tateishi; Raku Sonoo; Yu-ichi Sekiya; Nanae Sunahara; Miwako Kawano; Mitsutoshi Wayama; Ryuichi Hirota; Yoh-ichi Kawabe; Akiko Murayama; Shigeaki Kato; Keiji Kimura; Junn Yanagisawa
Turning off estrogen receptor beta-mediated transcription requires estrogen-dependent receptor proteolysis.
Molecular and cellular biology 2006;26(21):7966-76.
2006: Shigeaki Kato
[Molecular mechanism of tissue-specific actions of SERM].
Clinical calcium 2006;16(9):1469-74.
2006: Techuan Chan; Reiko Satow; Hirochika Kitagawa; Shigeaki Kato; Makoto Asashima
Ledgerline, a novel Xenopus laevis gene, regulates differentiation of presomitic mesoderm during somitogenesis.
Zoological science 2006;23(8):689-97.
2006: Takashi Yamada; Hirotaka Kawano; Yu Koshizuka; Toru Fukuda; Kimihiro Yoshimura; Satoru Kamekura; Taku Saito; Toshiyuki Ikeda; Yosuke Kawasaki; Yoshiaki Azuma; Shiro Ikegawa; Kazuto Hoshi; Ung-il Chung; Kozo Nakamura; Shigeaki Kato; Hiroshi Kawaguchi
Carminerin contributes to chondrocyte calcification during endochondral ossification.
Nature medicine 2006;12(6):665-70.
2006: Masahiko Kishimoto; Ryoji Fujiki; Shinichiro Takezawa; Yasumasa Sasaki; Takashi Nakamura; Kazuyoshi Yamaoka; Hirochika Kitagawa; Shigeaki Kato
Nuclear receptor mediated gene regulation through chromatin remodeling and histone modifications.
Endocrine journal 2006;53(2):157-72.
2006: Haeng-Seog Lee; Shin-ichi Sasagawa; Shigeaki Kato; Ryouichi Fukuda; Hiroyuki Horiuchi; Akinori Ohta
Yeast two-hybrid detection systems that are highly sensitive to a certain kind of endocrine disruptors.
Bioscience, biotechnology, and biochemistry 2006;70(2):521-4.
2006: Hajime Oishi; Hirochika Kitagawa; Osamu Wada; Shinichiro Takezawa; Làszlò Tora; Madoka Kouzu-Fujita; Ichiro Takada; Tetsu Yano; Junn Yanagisawa; Shigeaki Kato
An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification.
The Journal of biological chemistry 2006;281(1):20-6.
2006: Hiroko Shiina; Takahiro Matsumoto; Takashi Sato; Katsuhide Igarashi; Junko Miyamoto; Sayuri Takemasa; Matomo Sakari; Ichiro Takada; Takashi Nakamura; Daniel Metzger; Pierre Chambon; Jun Kanno; Hiroyuki Yoshikawa; Shigeaki Kato
Premature ovarian failure in androgen receptor-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(1):224-9.
2006: Kimiko Yamamoto; Takaaki Sokabe; Takahiro Matsumoto; Kimihiro Yoshimura; Masahiro Shibata; Norihiko Ohura; Toru Fukuda; Takashi Sato; Keisuke Sekine; Shigeaki Kato; Masashi Isshiki; Toshiro Fujita; Mikio Kobayashi; Koichi Kawamura; Hirotake Masuda; Akira Kamiya; Joji Ando
Impaired flow-dependent control of vascular tone and remodeling in P2X4-deficient mice.
Nature medicine 2006;12(1):133-7.
2005: Satoko Ogawa; Hajime Oishi; Yoshihiro Mezaki; Madoka Kouzu-Fujita; Reiko Matsuyama; Madoka Nakagomi; Eri Mori; Emi Murayama; Hiromichi Nagasawa; Hirochika Kitagawa; Junn Yanagisawa; Tetsu Yano; Shigeaki Kato
Repressive domain of unliganded human estrogen receptor alpha associates with Hsc70.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(12):1095-102.
2005: Ryoji Fujiki; Mi-sun Kim; Yasumasa Sasaki; Kimihiro Yoshimura; Hirochika Kitagawa; Shigeaki Kato
Ligand-induced transrepression by VDR through association of WSTF with acetylated histones.
The EMBO journal 2005;24(22):3881-94.
2005: Shigeaki Kato; Takashi Sato; Tomoyuki Watanabe; Sayuri Takemasa; Yoshikazu Masuhiro; Fumiaki Ohtake; Takahiro Matsumoto
Function of nuclear sex hormone receptors in gene regulation.
Cancer chemotherapy and pharmacology 2005;56 Suppl 1():4-9.
2005: Takahiro Matsumoto; Ken-ichi Takeyama; Takashi Sato; Shigeaki Kato
Study of androgen receptor functions by genetic models.
Journal of biochemistry 2005;138(2):105-10.
2005: O Wada-Hiraike; Tetsu Yano; Tomomi Nei; Yoshitsugu Matsumoto; Kenji Nagasaka; Shin Takizawa; H Oishi; T Arimoto; Shunsuke Nakagawa; Toshiharu Yasugi; Shigeaki Kato; Yuji Taketani
The DNA mismatch repair gene hMSH2 is a potent coactivator of oestrogen receptor alpha.
British journal of cancer 2005;92(12):2286-91.
2005: Yoshikazu Masuhiro; Yoshihiro Mezaki; Matomo Sakari; Ken-ichi Takeyama; Tasuku Yoshida; Kunio Inoue; Junn Yanagisawa; Shigemasa Hanazawa; Bert W O'Malley; Shigeaki Kato
Splicing potentiation by growth factor signals via estrogen receptor phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(23):8126-31.
2005: Shigeaki Kato
[Molecular mechanism of tissue-specific actions of sex steroid hormones and SERM for bone remodeling].
Clinical calcium 2005;15(5):825-30.
2005: Atsushi Unno; Ichiro Takada; Shinichiro Takezawa; Hajime Oishi; Atsushi Baba; Takafumi Shimizu; Akifumi Tokita; Junn Yanagisawa; Shigeaki Kato
TRRAP as a hepatic coactivator of LXR and FXR function.
Biochemical and biophysical research communications 2005;327(3):933-8.
2005: Ichiro Takada; Miyuki Suzawa; Shigeaki Kato
Nuclear receptors as targets for drug development: crosstalk between peroxisome proliferator-activated receptor gamma and cytokines in bone marrow-derived mesenchymal stem cells.
Journal of pharmacological sciences 2005;97(2):184-9.
2004: Yukiyo Tateishi; Yoh-ichi Kawabe; Tomoki Chiba; Shigeo Murata; Ken Ichikawa; Akiko Murayama; Keiji Tanaka; Tadashi Baba; Shigeaki Kato; Junn Yanagisawa
Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor.
The EMBO journal 2004;23(24):4813-23.
2004: Shigeaki Kato; Yamamoto Yoko
[VDR function in skin].
Clinical calcium 2004;14(10):116-9.
2004: Saya Ito; Ken-ichi Takeyama; Ayako Yamamoto; Shun Sawatsubashi; Yuko Shirode; Alexander Kouzmenko; Tetsuya Tabata; Shigeaki Kato
In vivo potentiation of human oestrogen receptor alpha by Cdk7-mediated phosphorylation.
Genes to cells : devoted to molecular & cellular mechanisms 2004;9(10):983-92.
2004: Alexander Kouzmenko; Ken-ichi Takeyama; Saya Ito; Takashi Furutani; Shun Sawatsubashi; Akio Maki; Eriko Suzuki; Yoshihiro Kawasaki; Tetsu Akiyama; Testuya Tabata; Shigeaki Kato
Wnt/beta-catenin and estrogen signaling converge in vivo.
The Journal of biological chemistry 2004;279(39):40255-8.
2004: Takashi Yamada; Hirotaka Kawano; Keisuke Sekine; Takahiro Matsumoto; Toru Fukuda; Yoshiaki Azuma; Keiji Itaka; Ung-il Chung; Pierre Chambon; Kozo Nakamura; Shigeaki Kato; Hiroshi Kawaguchi
SRC-1 is necessary for skeletal responses to sex hormones in both males and females.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(9):1452-61.
2004: Osamu Wada; Hajime Oishi; Ichiro Takada; Junn Yanagisawa; Tetsu Yano; Shigeaki Kato
BRCA1 function mediates a TRAP/DRIP complex through direct interaction with TRAP220.
Oncogene 2004;23(35):6000-5.
2004: Shun Sawatsubashi; Akio Maki; Saya Ito; Yuko Shirode; Eriko Suzuki; Yue Zhao; Kaoru Yamagata; Alexander Kouzmenko; Ken-ichi Takeyama; Shigeaki Kato
Ecdysone receptor-dependent gene regulation mediates histone poly(ADP-ribosyl)ation.
Biochemical and biophysical research communications 2004;320(1):268-72.
2004: Akio Maki; Shun Sawatsubashi; Saya Ito; Yuko Shirode; Eriko Suzuki; Yue Zhao; Kaoru Yamagata; Alexander Kouzmenko; Ken-ichi Takeyama; Shigeaki Kato
Juvenile hormones antagonize ecdysone actions through co-repressor recruitment to EcR/USP heterodimers.
Biochemical and biophysical research communications 2004;320(1):262-7.
2004: Ken-ichi Takeyama; Saya Ito; Shun Sawatsubashi; Yuko Shirode; Ayako Yamamoto; Eriko Suzuki; Akio Maki; Kaoru Yamagata; Yue Zhao; Alexandre Kouzmenko; Tetsuya Tabata; Shigeaki Kato
A novel genetic system for analysis of co-activators for the N-terminal transactivation function domain of the human androgen receptor.
Bioscience, biotechnology, and biochemistry 2004;68(6):1209-15.
2004: Shigeaki Kato; Takahiro Matsumoto; Hirotaka Kawano; Takashi Sato; Ken-ichi Takeyama
Function of androgen receptor in gene regulations.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):627-33.
2004: Shigeaki Kato; Ryoji Fujiki; Hirochika Kitagawa
Vitamin D receptor (VDR) promoter targeting through a novel chromatin remodeling complex.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):173-8.
2004: Akiko Murayama; Mi-sun Kim; Junn Yanagisawa; Ken-ichi Takeyama; Shigeaki Kato
Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching.
The EMBO journal 2004;23(7):1598-608.
2004: Takashi Sato; Takahiro Matsumoto; Hirotaka Kawano; Tomoyuki Watanabe; Yoshikatsu Uematsu; Keisuke Sekine; Toru Fukuda; Ken-ichi Aihara; Andrée Krust; Takashi Yamada; Yuko Nakamichi; Yoko Yamamoto; Takashi Nakamura; Kimihiro Yoshimura; Tatsuya Yoshizawa; Daniel Metzger; Pierre Chambon; Shigeaki Kato
Brain masculinization requires androgen receptor function.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(6):1673-8.
2004: Ichiro Takada; Shigeaki Kato
[PPARgamma and bone metabolism].
Clinical calcium 2004;14(2):269-74.
2003: Yasuji Yamamoto; Osamu Wada; Ichiro Takada; Yoshiko Yogiashi; Jiro Shibata; Junn Yanagisawa; Kenji Kitazato; Shigeaki Kato
Both N- and C-terminal transactivation functions of DNA-bound ERalpha are blocked by a novel synthetic estrogen ligand.
Biochemical and biophysical research communications 2003;312(3):656-62.
2003: Hirotaka Kawano; Hiroshi Kawaguchi; Shigeaki Kato
[Bone metabolism in androgen receptor-deficient mice].
Clinical calcium 2003;13(11):1443-5.
2003: Hirotaka Kawano; Takashi Sato; Takashi Yamada; Takahiro Matsumoto; Keisuke Sekine; Tomoyuki Watanabe; Takashi Nakamura; Toru Fukuda; Kimihiro Yoshimura; Tatsuya Yoshizawa; Ken-Ichi Aihara; Yoko Yamamoto; Yuko Nakamichi; Daniel Metzger; Pierre Chambon; Kozo Nakamura; Hiroshi Kawaguchi; Shigeaki Kato
Suppressive function of androgen receptor in bone resorption.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(16):9416-21.
2003: Tetsuo Fujita; Yoko Kobayashi; Osamu Wada; Yukiyo Tateishi; Lina Kitada; Yasuji Yamamoto; Hisashige Takashima; Akiko Murayama; Tetsu Yano; Tadashi Baba; Shigeaki Kato; Yoh-Ichi Kawabe; Junn Yanagisawa
Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells.
The Journal of biological chemistry 2003;278(29):26704-14.
2003: Ken Ishitani; Tasuku Yoshida; Hirochika Kitagawa; Hiroaki Ohta; Shiro Nozawa; Shigeaki Kato
p54nrb acts as a transcriptional coactivator for activation function 1 of the human androgen receptor.
Biochemical and biophysical research communications 2003;306(3):660-5.
2003: Hirochika Kitagawa; Ryoji Fujiki; Kimihiro Yoshimura; Yoshihiro Mezaki; Yoshikatsu Uematsu; Daisuke Matsui; Satoko Ogawa; Kiyoe Unno; Mataichi Okubo; Akifumi Tokita; Takeya Nakagawa; Takashi Ito; Yukio Ishimi; Hiromichi Nagasawa; Toshio Matsumoto; Junn Yanagisawa; Shigeaki Kato
The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.
Cell 2003;113(7):905-17.
2003: Fumiaki Ohtake; Ken-ichi Takeyama; Takahiro Matsumoto; Hirochika Kitagawa; Yasuji Yamamoto; Keiko Nohara; Chiharu Tohyama; Andrée Krust; Junsei Mimura; Pierre Chambon; Junn Yanagisawa; Yoshiaki Fujii-Kuriyama; Shigeaki Kato
Modulation of oestrogen receptor signalling by association with the activated dioxin receptor.
Nature 2003;423(6939):545-50.
2003: G Dimitrova; Shigeaki Kato; Hidetoshi Yamashita; Yasuhiro Tamaki; Miyuki Nagahara; Harumi Fukushima; Shigehiko Kitano
Relation between retrobulbar circulation and progression of diabetic retinopathy.
The British journal of ophthalmology 2003;87(5):622-5.
2003: Kou Yokouchi; Masanori Ito; Koichiro Nishino; Keitaro Yamanouchi; Kunihiko Naito; Miyuki Suzawa; Shigeaki Kato; Yoji Hakamata; Hitoshi Endo; Hideaki Tojo
Stage-specific regulatory element of mouse Sry gene.
Molecular reproduction and development 2003;64(4):389-96.
2003: Miyuki Suzawa; Ichiro Takada; Junn Yanagisawa; Fumiaki Ohtake; Satoko Ogawa; Toshimasa Yamauchi; Takashi Kadowaki; Yasuhiro Takeuchi; Hiroshi Shibuya; Yukiko Gotoh; Kunihiro Matsumoto; Shigeaki Kato
Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade.
Nature cell biology 2003;5(3):224-30.
2003: Takashi Sato; Takahiro Matsumoto; Takashi Yamada; Tomoyuki Watanabe; Hirotaka Kawano; Shigeaki Kato
Late onset of obesity in male androgen receptor-deficient (AR KO) mice.
Biochemical and biophysical research communications 2003;300(1):167-71.
2003: Shigeaki Kato; Ken-ichi Takeyama
Expression cloning of ligand biosynthetic enzymes.
Methods in enzymology 2003;364():361-75.
2003: Shigeaki Kato; Miyuki Suzawa; Ichiro Takada; Ken-ichi Takeyama; Jun Yanagizawa; Ryoji Fujiki; Hirochika Kitagawa
The function of nuclear receptors in bone tissues.
Journal of bone and mineral metabolism 2003;21(6):323-36.
2003: Yuko Nakamichi; Chisa Shukunami; Takashi Yamada; Ken-ichi Aihara; Hirotaka Kawano; Takashi Sato; Yuriko Nishizaki; Yoko Yamamoto; Masayo Shindo; Kimihiro Yoshimura; Takashi Nakamura; Naoyuki Takahashi; Hiroshi Kawaguchi; Yuji Hiraki; Shigeaki Kato
Chondromodulin I is a bone remodeling factor.
Molecular and cellular biology 2003;23(2):636-44.
2003: Masako Kato; Takao Shinozawa; Shigeaki Kato; T Terada
Immunohistochemical localization of truncated midkine in developing human bile ducts.
Histology and histopathology 2003;18(1):129-34.
2002: Shigeaki Kato
[Molecular mechanism of tissue-specific actions of SERM].
Clinical calcium 2002;12(12):1695-700.
2002: Yasuo Yanagi; Shin-Ichiro Takezawa; Shigeaki Kato
Distinct functions of photoreceptor cell-specific nuclear receptor, thyroid hormone receptor beta2 and CRX in one photoreceptor development.
Investigative ophthalmology & visual science 2002;43(11):3489-94.
2002: G Dimitrova; Yasuhiro Tamaki; Shigeaki Kato
Retrobulbar circulation in patients with age-related maculopathy.
Eye (London, England) 2002;16(5):580-6.
2002: Ken-ichi Takeyama; Saya Ito; Ayako Yamamoto; Hiromu Tanimoto; Takashi Furutani; Hirotaka Kanuka; Masayuki Miura; Tetsuya Tabata; Shigeaki Kato
Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.
Neuron 2002;35(5):855-64.
2002: G Dimitrova; Yasuhiro Tamaki; Shigeaki Kato; Miyuki Nagahara
Retrobulbar circulation in myopic patients with or without myopic choroidal neovascularisation.
The British journal of ophthalmology 2002;86(7):771-3.
2002: Hirochika Kitagawa; Junn Yanagisawa; Hiroaki Fuse; Satoko Ogawa; Yoshiko Yogiashi; Atsuro Okuno; Hiromichi Nagasawa; Toshihiro Nakajima; Toshio Matsumoto; Shigeaki Kato
Ligand-selective potentiation of rat mineralocorticoid receptor activation function 1 by a CBP-containing histone acetyltransferase complex.
Molecular and cellular biology 2002;22(11):3698-706.
2002: Daisuke Matsui; Matomo Sakari; Takashi Sato; Akiko Murayama; Ichiro Takada; Misun Kim; Ken-ichi Takeyama; Shigeaki Kato
Transcriptional regulation of the mouse steroid 5alpha-reductase type II gene by progesterone in brain.
Nucleic acids research 2002;30(6):1387-93.
2002: Junn Yanagisawa; Hirochika Kitagawa; Mitsuaki Yanagida; Osamu Wada; Satoko Ogawa; Madoka Nakagomi; Hajime Oishi; Yasuji Yamamoto; Hiromich Nagasawa; Steven B McMahon; Michael D Cole; Làszlò Tora; Nobuhiro Takahashi; Shigeaki Kato
Nuclear receptor function requires a TFTC-type histone acetyl transferase complex.
Molecular cell 2002;9(3):553-62.
2002: Haeng-Seog Lee; Keisuke Miyauchi; Yuji Nagata; Ryouichi Fukuda; Shin-ichi Sasagawa; Hideki Endoh; Shigeaki Kato; Hiroyuki Horiuchi; Masamichi Takagi; Akinori Ohta
Employment of the human estrogen receptor beta ligand-binding domain and co-activator SRC1 nuclear receptor-binding domain for the construction of a yeast two-hybrid detection system for endocrine disrupters.
Journal of biochemistry 2002;131(3):399-405.
2002: Miyuki Suzawa; Yasuhiro Tamura; Seiji Fukumoto; Kohei Miyazono; Toshiro Fujita; Shigeaki Kato; Yasuhiro Takeuchi
Stimulation of Smad1 transcriptional activity by Ras-extracellular signal-regulated kinase pathway: a possible mechanism for collagen-dependent osteoblastic differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(2):240-8.
2002: Takashi Sato; Hirotaka Kawano; Shigeaki Kato
Study of androgen action in bone by analysis of androgen-receptor deficient mice.
Journal of bone and mineral metabolism 2002;20(6):326-30.
2002: Shigeaki Kato; Tatsuya Yoshizazawa; Sachiko Kitanaka; Akiko Murayama; Ken-ichi Takeyama
Molecular genetics of vitamin D- dependent hereditary rickets.
Hormone research 2002;57(3-4):73-8.
2002: Tatsuo Shimosawa; Yugo Shibagaki; Kotaro Ishibashi; Kazuo Kitamura; Kenji Kangawa; Shigeaki Kato; Katsuyuki Ando; Toshiro Fujita
Adrenomedullin, an endogenous peptide, counteracts cardiovascular damage.
Circulation 2002;105(1):106-11.
2001: Yoshihiro Mezaki; Tasuku Yoshida; Junn Yanagisawa; Shigeaki Kato
N-terminal activation function is dominant in ligand-dependent transactivation of medaka estrogen receptor alpha in human cells.
Biochemical and biophysical research communications 2001;289(3):763-8.
2001: Shigeaki Kato
[Transcriptional control of vitamin D1alpha-hydroxylase gene by PTH].
Clinical calcium 2001;11(12):1606-11.
2001: Miki Takikawa; Shigeaki Kato; H Esumi; Y Kurashima; Asao Hirano; Kohtaro Asayama; Kenji Nakashima; Eisaku Ohama
Temporospatial relationship between the expressions of superoxide dismutase and nitric oxide synthase in the developing human brain: immunohistochemical and immunoblotting analyses.
Acta neuropathologica 2001;102(6):572-80.
2001: N Yagishita; Yoko Yamamoto; Tatsuya Yoshizawa; Keisuke Sekine; Yoshikatsu Uematsu; H Murayama; Y Nagai; W Krezel; Pierre Chambon; Toshio Matsumoto; Shigeaki Kato
Aberrant growth plate development in VDR/RXR gamma double null mutant mice.
Endocrinology 2001;142(12):5332-41.
2001: Yasuji Yamamoto; Osamu Wada; Miyuki Suzawa; Yoshiko Yogiashi; Tetsu Yano; Shigeaki Kato; Junn Yanagisawa
The tamoxifen-responsive estrogen receptor alpha mutant D351Y shows reduced tamoxifen-dependent interaction with corepressor complexes.
The Journal of biological chemistry 2001;276(46):42684-91.
2001: Miyuki Suzawa; Shigeaki Kato
[A clinical perspective, a frontiers of PPAR function].
Nihon rinsho. Japanese journal of clinical medicine 2001;59(11):2269-77.
2001: G Dimitrova; Shigeaki Kato; Yasuhiro Tamaki; Hidetoshi Yamashita; Miyuki Nagahara; M Sakurai; Shigehiko Kitano; Harumi Fukushima
Choroidal circulation in diabetic patients.
Eye (London, England) 2001;15(Pt 5):602-7.
2001: Tetsuro Oshika; S Santou; Shigeaki Kato; Shiro Amano
Secondary closure of neodymium:YAG laser posterior capsulotomy.
Journal of cataract and refractive surgery 2001;27(10):1695-7.
2001: Toshimasa Yamauchi; Hironori Waki; Junji Kamon; Koji Murakami; Kiyoto Motojima; Kajuro Komeda; Hiroshi Miki; Naoto Kubota; Yasuo Terauchi; Atsushi Tsuchida; Nobuyo Tsuboyama-Kasaoka; N Yamauchi; Tomohiro Ide; W Hori; Shigeaki Kato; Masashi Fukayama; Yasuo Akanuma; Osamu Ezaki; Akiko Itai; Ryozo Nagai; Satoshi Kimura; Kazuyuki Tobe; Hiroyuki Kagechika; Koichi Shudo; Takashi Kadowaki
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes.
The Journal of clinical investigation 2001;108(7):1001-13.
2001: Shigeaki Kato; H Sumi-Akamaru; H Fujimura; S Sakoda; Masako Kato; Asao Hirano; Miki Takikawa; Eisaku Ohama
Copper chaperone for superoxide dismutase co-aggregates with superoxide dismutase 1 (SOD1) in neuronal Lewy body-like hyaline inclusions: an immunohistochemical study on familial amyotrophic lateral sclerosis with SOD1 gene mutation.
Acta neuropathologica 2001;102(3):233-8.
2001: Harumi Fukushima; Shigeaki Kato; Tadayoshi Kaiya; Takuma Yuguchi; K Ohara; Hidetaka Noma; Y Konno; K Kameyama; Tetsuro Oshika
Effect of subconjunctival steroid injection on intraocular inflammation and blood glucose level after cataract surgery in diabetic patients.
Journal of cataract and refractive surgery 2001;27(9):1386-91.
2001: S Kitanaka; Ken-ichi Takeyama; Akiko Murayama; Shigeaki Kato
The molecular basis of vitamin D-dependent rickets type I.
Endocrine journal 2001;48(4):427-32.
2001: Arun Kumar Adhikary; Jiro Numaga; Toshikatsu Kaburaki; H Kawashima; Shigeaki Kato; Makoto Araie; Kazunori Miyata; Hideaki Shimizu; Fumihiro Yagyu; Eiko Suzuki; Hiroshi Ushijima
Rapid detection and typing of oculopathogenic strain of subgenus D adenoviruses by fiber-based PCR and restriction enzyme analysis.
Investigative ophthalmology & visual science 2001;42(9):2010-5.
2001: Shigeaki Kato; Masako Kato; Asao Hirano; Miki Takikawa; Eisaku Ohama
The immunohistochemical expression of stress-response protein (srp) 60 in human brain tumours: relationship of srp 60 to the other five srps, proliferating cell nuclear antigen and p53 protein.
Histology and histopathology 2001;16(3):809-20.
2001: H Matsuda; Shigeaki Kato; Yoshie Hayashi; Shiro Amano; T Hattori; Takuma Yuguchi; Tadayoshi Kaiya; Tetsuro Oshika
Anterior capsular contraction after cataract surgery in vitrectomized eyes.
American journal of ophthalmology 2001;132(1):108-9.
2001: Harumi Fukushima; Shigeaki Kato; Y Hayashi; Tetsuro Oshika
Influence of subconjunctival steroid injection on blood glucose profile in diabetic rats.
Eye (London, England) 2001;15(Pt 3):326-8.
2001: Shigeaki Kato
[Molucular mechanism of vitamin D actions].
Clinical calcium 2001;11(4):397-403.
2001: K Inoue; Jiro Numaga; S Joko; S Izumi; Shigeaki Kato; Hidetoshi Kawashima; Yujiro Fujino
A case of multiple sclerosis with granulomatous uveitis in Japan--use of the antilipoarabinomannan (LAM)-B test in differential diagnosis.
American journal of ophthalmology 2001;131(4):524-6.
2001: M Watanabe; Junn Yanagisawa; Hirochika Kitagawa; Ken-ichi Takeyama; Satoko Ogawa; Yukitomo Arao; Miyuki Suzawa; Y Kobayashi; Tetsu Yano; H Yoshikawa; Yoshikazu Masuhiro; Shigeaki Kato
A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA.
The EMBO journal 2001;20(6):1341-52.
2001: Shigeaki Kato; Kenji Nakashima; S Horiuchi; R Nagai; DW Cleveland; J Liu; Asao Hirano; Miki Takikawa; Masako Kato; Imaharu Nakano; S Sakoda; Kohtaro Asayama; Eisaku Ohama
Formation of advanced glycation end-product-modified superoxide dismutase-1 (SOD1) is one of the mechanisms responsible for inclusions common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutation, and transgenic mice expressing human SOD1 gene mutation.
Neuropathology : official journal of the Japanese Society of Neuropathology 2001;21(1):67-81.
2001: Shigeaki Kato; A Shiokawa; Harumi Fukushima; Jiro Numaga; Shigehiko Kitano; Sadao Hori; Tadayoshi Kaiya; Tetsuro Oshika
Glycemic control and lens transparency in patients with type 1 diabetes mellitus.
American journal of ophthalmology 2001;131(3):301-4.
2001: S I Sasagawa; Shigeaki Kato
A nuclear receptor screening method using a steroid receptor coactivator-1 fragment in a yeast two-hybrid system.
Analytical biochemistry 2001;289(2):295-7.
2001: Shigeaki Kato; Tetsuro Oshika; Jiro Numaga; Yoshie Hayashi; M Oshiro; Takuma Yuguchi; Tadayoshi Kaiya
Anterior capsular contraction after cataract surgery in eyes of diabetic patients.
The British journal of ophthalmology 2001;85(1):21-3.
2000: Shigeaki Kato
Molecular mechanism of transcriptional control by nuclear vitamin receptors.
The British journal of nutrition 2000;84 Suppl 2():S229-33.
2000: Shigeaki Kato
[Transcriptional control by nuclear steroid hormone receptors and endocrine disruptants].
Nihon rinsho. Japanese journal of clinical medicine 2000;58(12):2439-45.
2000: K Inoue; Shigeaki Kato; Jiro Numaga; M Sakurai; C Ohara; M Ouchi; Takeshi Iwata; Hidetoshi Kawashima
Optic disk pallor and retinal atrophy in Sotos syndrome (cerebral gigantism).
American journal of ophthalmology 2000;130(6):853-4.
2000: K Inoue; Jiro Numaga; Yuichi Kaji; Junko Toda; Shigeaki Kato; M Sakurai; M Ikeda; Noriko Motoi; T Murakami; Yujiro Fujino
Bilateral choroidal metastases secondary to uterocervical carcinoma of the squamous cell type.
American journal of ophthalmology 2000;130(5):682-4.
2000: Shigeaki Kato; S Horiuchi; J Liu; DW Cleveland; N Shibata; Kenji Nakashima; R Nagai; Asao Hirano; Miki Takikawa; Masako Kato; Imaharu Nakano; Eisaku Ohama
Advanced glycation endproduct-modified superoxide dismutase-1 (SOD1)-positive inclusions are common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutations and transgenic mice expressing human SOD1 with a G85R mutation.
Acta neuropathologica 2000;100(5):490-505.
2000: Shigeaki Kato; Takao Shinozawa; Miki Takikawa; Masako Kato; Asao Hirano; Akira Awaya; Eisaku Ohama
Midkine, a new neurotrophic factor, is present in glial cytoplasmic inclusions of multiple system atrophy brains.
Acta neuropathologica 2000;100(5):481-9.
2000: Y Kodera; Ken-ichi Takeyama; Akiko Murayama; Miyuki Suzawa; Yoshikazu Masuhiro; Shigeaki Kato
Ligand type-specific interactions of peroxisome proliferator-activated receptor gamma with transcriptional coactivators.
The Journal of biological chemistry 2000;275(43):33201-4.
2000: Y Watanabe; Shigeaki Kato; Y Adachi; Kenji Nakashima
Frameshift, nonsense and non amino acid altering mutations in SOD1 in familial ALS: report of a Japanese pedigree and literature review.
Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 2000;1(4):251-8.
2000: Shigeaki Kato; Tetsuro Oshika; Jiro Numaga; Hidetoshi Kawashima; Shigehiko Kitano; Tadayoshi Kaiya
Influence of rapid glycemic control on lens opacity in patients with diabetes mellitus.
American journal of ophthalmology 2000;130(3):354-5.
2000: Yukitomo Arao; R Kuriyama; Fujio Kayama; Shigeaki Kato
A nuclear matrix-associated factor, SAF-B, interacts with specific isoforms of AUF1/hnRNP D.
Archives of biochemistry and biophysics 2000;380(2):228-36.
2000: Shigeaki Kato; Yoshikazu Masuhiro; Masahiko Watanabe; Y Kobayashi; Ken-ichi Takeyama; H Endoh; Junn Yanagisawa
Molecular mechanism of a cross-talk between oestrogen and growth factor signalling pathways.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(8):593-601.
2000: Shigeaki Kato
[Nuclear steroid hormone receptors as possible target molecule for endocrine disruptant].
Nihon rinsho. Japanese journal of clinical medicine 2000;58(7):1535-43.
2000: Shigeaki Kato; Miki Takikawa; Kenji Nakashima; Asao Hirano; DW Cleveland; H Kusaka; N Shibata; Masako Kato; Imaharu Nakano; Eisaku Ohama
New consensus research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 (SOD1) gene mutations: inclusions containing SOD1 in neurons and astrocytes.
Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 2000;1(3):163-84.
2000: Shigeaki Kato
[Transcriptional control by nuclear vitamin A/D receptors].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(9 Suppl):1534-45.
2000: Shigeaki Kato
[Activation of transcriptional factor by signal transduction: overview].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(9 Suppl):1523-5.
2000: Masako Kato; Takao Shinozawa; Shigeaki Kato; Akira Awaya; Tadashi Terada
Increased midkine expression in hepatocellular carcinoma.
Archives of pathology & laboratory medicine 2000;124(6):848-52.
2000: Y Kobayashi; T Kitamoto; Yoshikazu Masuhiro; M Watanabe; T Kase; D Metzger; Junn Yanagisawa; Shigeaki Kato
p300 mediates functional synergism between AF-1 and AF-2 of estrogen receptor alpha and beta by interacting directly with the N-terminal A/B domains.
The Journal of biological chemistry 2000;275(21):15645-51.
2000: Shigeaki Kato
The function of vitamin D receptor in vitamin D action.
Journal of biochemistry 2000;127(5):717-22.
2000: Shigeaki Kato; Keisuke Sekine
[FGF10, a key factor for limb and lung formation].
Seikagaku. The Journal of Japanese Biochemical Society 2000;72(4):288-91.
2000: Shigeaki Kato
[Transcriptional control by nuclear receptors and its application to drug development].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(6 Suppl):950-5.
2000: Yasuo Yanagi; Yoshikazu Masuhiro; Masatomo Mori; Junn Yanagisawa; Shigeaki Kato
p300/CBP acts as a coactivator of the cone-rod homeobox transcription factor.
Biochemical and biophysical research communications 2000;269(2):410-4.
2000: Ken-ichi Takeyama; Y Kodera; Miyuki Suzawa; Shigeaki Kato
[Peroxisome proliferator-activated receptor(PPAR)--structure, function, tissue distribution, gene expression].
Nihon rinsho. Japanese journal of clinical medicine 2000;58(2):357-63.
1999: K Muranaka; Shiho Kunimatsu; Yuichi Kaji; S Joko; Shigeaki Kato; Jiro Numaga
Conjunctival haemangioma in an elderly patient.
Eye (London, England) 1999;13 ( Pt 6)():790.
1999: K Chida; Y Fukui; Shigeaki Kato; H Itoh
[How signal transduction systems look like after recent dramatic progress].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(16):2535-64.
1999: T Kumagami; Shigeaki Kato; R Ishikura; M Nagata; A Tamai; Eisaku Ohama
Expression of stress-response protein 60 in iritis associated with experimental autoimmune encephalomyelitis.
Japanese journal of ophthalmology 1999;43(6):458-65.
1999: S Kitanaka; Akiko Murayama; T Sakaki; K Inouye; Y Seino; S Fukumoto; M Shima; S Yukizane; M Takayanagi; H Niimi; Ken-ichi Takeyama; Shigeaki Kato
No enzyme activity of 25-hydroxyvitamin D3 1alpha-hydroxylase gene product in pseudovitamin D deficiency rickets, including that with mild clinical manifestation.
The Journal of clinical endocrinology and metabolism 1999;84(11):4111-7.
1999: Shigeaki Kato
Genetic mutation in the human 25-hydroxyvitamin D3 1alpha-hydroxylase gene causes vitamin D-dependent rickets type I.
Molecular and cellular endocrinology 1999;156(1-2):7-12.
1999: Ken-ichi Takeyama; Shigeaki Kato
[Gene structure and transcriptional regulation of vitamin A, D binding proteins and nuclear receptors].
Nihon rinsho. Japanese journal of clinical medicine 1999;57(10):2284-94.
1999: Hiroyuki Nunoi; T Yamazaki; H Tsuchiya; Shigeaki Kato; H L Malech; I Matsuda; Shiro Kanegasaki
A heterozygous mutation of beta-actin associated with neutrophil dysfunction and recurrent infection.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8693-8.
1999: Shigeaki Kato; Keisuke Sekine
FGF-FGFR signaling in vertebrate organogenesis.
Cellular and molecular biology (Noisy-le-Grand, France) 1999;45(5):631-8.
1999: Shigeaki Kato; M Saito; Asao Hirano; Eisaku Ohama
Recent advances in research on neuropathological aspects of familial amyotrophic lateral sclerosis with superoxide dismutase 1 gene mutations: neuronal Lewy body-like hyaline inclusions and astrocytic hyaline inclusions.
Histology and histopathology 1999;14(3):973-89.
1999: Yasushi Horie; A Shigoku; H Tanaka; Y Tomie; N Maeda; U Hoshino; M Koda; Goshi Shiota; T Yamamoto; Shigeaki Kato; Yoshikazu Murawaki; Takeaki Suou; Hironaka Kawasaki
Prognosis for pedunculated hepatocellular carcinoma.
Oncology 1999;57(1):23-8.
1999: Tetsuro Oshika; Shiro Amano; Shigeaki Kato
Severe iridodialysis from phacoemulsification tip suction.
Journal of cataract and refractive surgery 1999;25(6):873-5.
1999: Yasuo Yanagi; Miyuki Suzawa; M Kawabata; Kohei Miyazono; Junn Yanagisawa; Shigeaki Kato
Positive and negative modulation of vitamin D receptor function by transforming growth factor-beta signaling through smad proteins.
The Journal of biological chemistry 1999;274(19):12971-4.
1999: Shigeaki Kato; K Ishihara; Takao Shinozawa; H Yamaguchi; Y Asano; M Saito; Masako Kato; Tadashi Terada; Akira Awaya; Asao Hirano; dennis dickson; Shu-Hui C. Yen; Eisaku Ohama
Monoclonal antibody to human midkine reveals increased midkine expression in human brain tumors.
Journal of neuropathology and experimental neurology 1999;58(5):430-41.
1999: A Murayama; Ken-ichi Takeyama; S Kitanaka; Y Kodera; Y Kawaguchi; T Hosoya; Shigeaki Kato
Positive and negative regulations of the renal 25-hydroxyvitamin D3 1alpha-hydroxylase gene by parathyroid hormone, calcitonin, and 1alpha,25(OH)2D3 in intact animals.
Endocrinology 1999;140(5):2224-31.
1999: Miyuki Suzawa; Yasuhiro Takeuchi; Seiji Fukumoto; Shigeaki Kato; N Ueno; Kohei Miyazono; T Matsumoto; Tomoyuki Fujita
Extracellular matrix-associated bone morphogenetic proteins are essential for differentiation of murine osteoblastic cells in vitro.
Endocrinology 1999;140(5):2125-33.
1999: Shigeaki Kato; Ken-ichi Takeyama; S Kitanaka; Akiko Murayama; Keisuke Sekine; Tatsuya Yoshizawa
In vivo function of VDR in gene expression-VDR knock-out mice.
The Journal of steroid biochemistry and molecular biology 1999;69(1-6):247-51.
1999: R Ishikura; Shigeaki Kato; M Nagata; A Tamai; Eisaku Ohama
Expression of stress-response protein 60 in lens epithelial cells in atopic cataract.
Japanese journal of ophthalmology 1999;43(2):89-96.
1999: Shigeaki Kato; S Horiuchi; Kenji Nakashima; Asao Hirano; N Shibata; Imaharu Nakano; M Saito; Masako Kato; Kohtaro Asayama; Eisaku Ohama
Astrocytic hyaline inclusions contain advanced glycation endproducts in familial amyotrophic lateral sclerosis with superoxide dismutase 1 gene mutation: immunohistochemical and immunoelectron microscopical analyses.
Acta neuropathologica 1999;97(3):260-6.
1999: Junn Yanagisawa; Yasuo Yanagi; Yoshikazu Masuhiro; Miyuki Suzawa; M Watanabe; K Kashiwagi; T Toriyabe; M Kawabata; Kohei Miyazono; Shigeaki Kato
Convergence of transforming growth factor-beta and vitamin D signaling pathways on SMAD transcriptional coactivators.
Science (New York, N.Y.) 1999;283(5406):1317-21.
1999: Keiichi Tanaka; K Horiguchi; Takashi Yoshida; Masafumi Takeda; H Fujisawa; Koh Takeuchi; Masato Umeda; Shigeaki Kato; Sayoko Ihara; Satoshi Nagata; Yasuhisa Fukui
Evidence that a phosphatidylinositol 3,4,5-trisphosphate-binding protein can function in nucleus.
The Journal of biological chemistry 1999;274(7):3919-22.
1999: S Takeda; T Yoshizawa; Y Nagai; H Yamato; Seiji Fukumoto; K Sekine; Shigeaki Kato; T Matsumoto; Tomoyuki Fujita
Stimulation of osteoclast formation by 1,25-dihydroxyvitamin D requires its binding to vitamin D receptor (VDR) in osteoblastic cells: studies using VDR knockout mice.
Endocrinology 1999;140(2):1005-8.
1999: Ken-ichi Takeyama; Yoshikazu Masuhiro; H Fuse; Hideki Endoh; Akiko Murayama; S Kitanaka; Miyuki Suzawa; Junn Yanagisawa; Shigeaki Kato
Selective interaction of vitamin D receptor with transcriptional coactivators by a vitamin D analog.
Molecular and cellular biology 1999;19(2):1049-55.
1999: Keisuke Sekine; H Ohuchi; M Fujiwara; M Yamasaki; Tatsuya Yoshizawa; Takashi Sato; N Yagishita; Daisuke Matsui; Y Koga; N Itoh; Shigeaki Kato
Fgf10 is essential for limb and lung formation.
Nature genetics 1999;21(1):138-41.
1998: Shigeaki Kato; T Kitamoto; Yoshikazu Masuhiro; Junn Yanagisawa
Molecular mechanism of a cross-talk between estrogen and growth-factor signaling pathways.
Oncology 1998;55 Suppl 1():5-10.
1998: Akiko Murayama; Ken-ichi Takeyama; S Kitanaka; Y Kodera; T Hosoya; Shigeaki Kato
The promoter of the human 25-hydroxyvitamin D3 1 alpha-hydroxylase gene confers positive and negative responsiveness to PTH, calcitonin, and 1 alpha,25(OH)2D3.
Biochemical and biophysical research communications 1998;249(1):11-6.
1998: Shigeaki Kato
[Molecular mechanisms of fat-soluble vitamins: vitamin receptor knockout mice].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(10):1321-35.
1998: Shigeaki Kato
[Transcriptional control by steroid receptor].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(7):1699-704.
1998: Shigeaki Kato; Junn Yanagisawa; Akiko Murayama; S Kitanaka; Ken-ichi Takeyama
The importance of 25-hydroxyvitamin D3 1 alpha-hydroxylase gene in vitamin D-dependent rickets.
Current opinion in nephrology and hypertension 1998;7(4):377-83.
1998: Shigeaki Kato; H Hayashi; K Mikoshiba; Asao Hirano; Shu-Hui C. Yen; Eisaku Ohama
Purkinje cells in olivopontocerebellar atrophy and granule cell-type cerebellar degeneration: an immunohistochemical study.
Acta neuropathologica 1998;96(1):67-74.
1998: Seiji Fukumoto; Miyuki Suzawa; T Kikuchi; T Matsumoto; Shigeaki Kato; Tomoyuki Fujita
Cloning and characterization of kidney-specific promoter of human PTH/PTHrP receptor gene: absence of mutation in patients with pseudohypoparathyroidism type Ib.
Molecular and cellular endocrinology 1998;141(1-2):41-7.
1998: Hiroyuki Kishimoto; Shin-ichi Hoshino; M Ohori; Kenji Kontani; Hiroshi Nishina; Miyuki Suzawa; Shigeaki Kato; Toshiaki Katada
Molecular mechanism of human CD38 gene expression by retinoic acid. Identification of retinoic acid response element in the first intron.
The Journal of biological chemistry 1998;273(25):15429-34.
1998: M Watanabe; Yasuo Yanagi; Yoshikazu Masuhiro; Tetsu Yano; H Yoshikawa; Junn Yanagisawa; Shigeaki Kato
A putative tumor suppressor, TSG101, acts as a transcriptional suppressor through its coiled-coil domain.
Biochemical and biophysical research communications 1998;245(3):900-5.
1998: S Kitanaka; Ken-ichi Takeyama; Akiko Murayama; T Sato; K Okumura; M Nogami; Y Hasegawa; H Niimi; Junn Yanagisawa; T Tanaka; Shigeaki Kato
Inactivating mutations in the 25-hydroxyvitamin D3 1alpha-hydroxylase gene in patients with pseudovitamin D-deficiency rickets.
The New England journal of medicine 1998;338(10):653-61.
1997: Hidetoshi Yamashita; I Tobari; M Sawa; Sadao Hori; Kohei Miyazono; C H Heldin; P Heldin; P T Dijke; T K Sampath; T Suiryu; S Eguchi; Shigehiko Kitano; S Suzuki; H Ichijo; M Kato; T Yamamoto; E Funazu; M Suzuki; Y Ikegami; Shigeaki Kato; H Obata; K Horie; Y Mogi; K Seiya; H Sakai
[Functions of the transforming growth factor-beta superfamily in eyes].
Nippon Ganka Gakkai zasshi 1997;101(12):927-47.
1997: Ken-ichi Takeyama; S Kitanaka; T Sato; M Kobori; Junn Yanagisawa; Shigeaki Kato
25-Hydroxyvitamin D3 1alpha-hydroxylase and vitamin D synthesis.
Science (New York, N.Y.) 1997;277(5333):1827-30.
1997: Shigeaki Kato; H Hayashi; Kenji Nakashima; Eiji Nanba; Masako Kato; Asao Hirano; Imaharu Nakano; Kohtaro Asayama; Eisaku Ohama
Pathological characterization of astrocytic hyaline inclusions in familial amyotrophic lateral sclerosis.
The American journal of pathology 1997;151(2):611-20.
1997: Tatsuya Yoshizawa; Y Handa; Yoshikatsu Uematsu; S Takeda; Keisuke Sekine; Y Yoshihara; T Kawakami; K Arioka; H Sato; Y Uchiyama; S Masushige; A Fukamizu; Toshio Matsumoto; Shigeaki Kato
Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning.
Nature genetics 1997;16(4):391-6.
1997: T Kumagami; Shigeaki Kato; Eisaku Ohama
[Expression of the stress-response protein 60 in iritis in experimental autoimmune encephalomyelitis--an immunohistochemical study].
Nippon Ganka Gakkai zasshi 1997;101(4):299-304.
1997: Shigeaki Kato
[Molecular mechanism of tissue-specific actions of oestrogen].
Seikagaku. The Journal of Japanese Biochemical Society 1997;69(1):30-6.
1996: Yukitomo Arao; N Miyatake; E Yamamoto; H Usiku; A Matsuura; Y Ninomiya; Shoichi Masushige; T Hasegawa; Shigeaki Kato
Steroid hormones differentially induce transcription of the chicken ovalbumin gene, but stabilize the mRNA with the same half-life.
Journal of biochemistry 1996;120(4):710-5.
1996: Shigeaki Kato; M Shimoda; Y Watanabe; K Nakashima; K Takahashi; Eisaku Ohama
Familial amyotrophic lateral sclerosis with a two base pair deletion in superoxide dismutase 1: gene multisystem degeneration with intracytoplasmic hyaline inclusions in astrocytes.
Journal of neuropathology and experimental neurology 1996;55(10):1089-101.
1996: Y Yamamoto; T Yoshizawa; H Mano; Shoichi Masushige; Shigeaki Kato
Bacterially expressed rat retinol-binding protein is functional for retinol and transthyretin bindings.
Journal of nutritional science and vitaminology 1996;42(4):257-66.
1996: K Ebihara; Yoshikazu Masuhiro; T Kitamoto; Miyuki Suzawa; Y Uematsu; T Yoshizawa; T Ono; H Harada; K Matsuda; T Hasegawa; Shoichi Masushige; Shigeaki Kato
Intron retention generates a novel isoform of the murine vitamin D receptor that acts in a dominant negative way on the vitamin D signaling pathway.
Molecular and cellular biology 1996;16(7):3393-400.
1996: K Takeyama; R Kojima; R Ohashi; Takahide Sato; H Mano; Shoichi Masushige; Shigeaki Kato
Retinoic acid differentially up-regulates the gene expression of retinoic acid receptor alpha and gamma isoforms in embryo and adult rats.
Biochemical and biophysical research communications 1996;222(2):395-400.
1996: Yukitomo Arao; E Yamamoto; Y Ninomiya; Shoichi Masushige; T Hasegawa; Shigeaki Kato
Steroid hormone-induced expression of the chicken ovalbumin gene and the levels of nuclear steroid hormone receptors in chick oviduct.
Bioscience, biotechnology, and biochemistry 1996;60(3):493-5.
1996: Y Ninomiya; Yukitomo Arao; T Kometani; S Hiwatashi; T Yamasaki; T Erikawa; H Yamaguchi; T Hasegawa; Shoichi Masushige; Shigeaki Kato
Vitamin A is involved in estrogen-induced cell proliferation but not in cytodifferentiation of the chicken oviduct.
The Journal of endocrinology 1996;148(2):257-65.
1996: H Mutoh; T Fukuda; T Kitamaoto; S Masushige; H Sasaki; T Shimizu; Shigeaki Kato
Tissue-specific response of the human platelet-activating factor receptor gene to retinoic acid and thyroid hormone by alternative promoter usage.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(2):774-9.
1996: T Shimizu; H Mutoh; Shigeaki Kato
Platelet-activating factor receptor. Gene structure and tissue-specific regulation.
Advances in experimental medicine and biology 1996;416():79-84.
1996: Yukitomo Arao; E Yamamoto; N Miyatake; Y Ninomiya; T Umehara; H Kawashima; Shoichi Masushige; T Hasegawa; Shigeaki Kato
A synthetic oestrogen antagonist, tamoxifen, inhibits oestrogen-induced transcriptional, but not post-transcriptional, regulation of gene expression.
The Biochemical journal 1996;313 ( Pt 1)():269-74.
1995: H Harada; R Miki; Shoichi Masushige; Shigeaki Kato
Gene expression of retinoic acid receptors, retinoid-X receptors, and cellular retinol-binding protein I in bone and its regulation by vitamin A.
Endocrinology 1995;136(12):5329-35.
1995: Shigeaki Kato; H Endoh; Yoshikazu Masuhiro; T Kitamoto; S Uchiyama; H Sasaki; Shoichi Masushige; Y Gotoh; E Nishida; H Kawashima; D Metzger; P Chambon
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase.
Science (New York, N.Y.) 1995;270(5241):1491-4.
1995: Shigeaki Kato; H Sasaki; Miyuki Suzawa; Shoichi Masushige; Làszlò Tora; P Chambon; Hinrich Gronemeyer
Widely spaced, directly repeated PuGGTCA elements act as promiscuous enhancers for different classes of nuclear receptors.
Molecular and cellular biology 1995;15(11):5858-67.
1995: Shigeaki Kato; T Morita; T Takenaka; Masako Kato; Asao Hirano; F Herz; Eisaku Ohama
Stress-response (heat-shock) protein 90 expression in tumors of the central nervous system: an immunohistochemical study.
Acta neuropathologica 1995;89(2):184-8.
1994: A Nagasaki; T Kikuchi; K Kurata; Shoichi Masushige; T Hasegawa; Shigeaki Kato
Vitamin A regulates the expression of apolipoprotein AI and CIII genes in the rat.
Biochemical and biophysical research communications 1994;205(3):1510-7.
1994: H Mutoh; Satoshi Ishii; Takashi Izumi; Shigeaki Kato; T Shimizu
Platelet-activating factor (PAF) positively auto-regulates the expression of human PAF receptor transcript 1 (leukocyte-type) through NF-kappa B.
Biochemical and biophysical research communications 1994;205(2):1137-42.
1994: H Mutoh; Kazuhiko Kume; Shinichi Sato; Shigeaki Kato; T Shimizu
Positive and negative regulations of human platelet-activating factor receptor transcript 2 (tissue-type) by estrogen and TGF-beta 1.
Biochemical and biophysical research communications 1994;205(2):1130-6.
1994: Shigeaki Kato
[Current topics in nuclear receptor study].
Nihon rinsho. Japanese journal of clinical medicine 1994;52(3):571-7.
1994: Shigeaki Kato; H Morino; H Mano; Shoichi Masushige
Evidence for other binding component(s) than retinoid receptors specifically interacting with a retinoic acid response element in the rat liver.
Journal of nutritional science and vitaminology 1994;40(1):1-10.
1994: H Mano; R Mori; T Ozawa; K Takeyama; Y Yoshizawa; R Kojima; Yukitomo Arao; Shoichi Masushige; Shigeaki Kato
Positive and negative regulation of retinoid X receptor gene expression by thyroid hormone in the rat. Transcriptional and post-transcriptional controls by thyroid hormone.
The Journal of biological chemistry 1994;269(3):1591-4.
1993: Shigeaki Kato; K Takeyama; R Kojima; Y Yoshizawa; T Furusho; H Mano; Shoichi Masushige
Gene expression of cellular retinol-binding protein I (CRBP I) is affected by dietary proteins in the rat liver.
Journal of nutritional science and vitaminology 1993;39(6):545-54.
1993: H Mano; T Ozawa; K Takeyama; Y Yoshizawa; R Kojima; Shigeaki Kato; Shoichi Masushige
Thyroid hormone affects the gene expression of retinoid X receptors in the adult rat.
Biochemical and biophysical research communications 1993;191(3):943-9.
1992: Y Ninomiya; Makoto Mochii; G Eguchi; T Hasegawa; Shoichi Masushige; Shigeaki Kato
Tissue-specific response of estrogen receptor gene expression to estrogen in chick.
Biochemical and biophysical research communications 1992;187(3):1374-80.
1992: Shigeaki Kato; H Mano; T Kumazawa; Y Yoshizawa; R Kojima; Shoichi Masushige
Effect of retinoid status on alpha, beta and gamma retinoic acid receptor mRNA levels in various rat tissues.
The Biochemical journal 1992;286 ( Pt 3)():755-60.
1992: Shigeaki Kato; T Oshika; H Funatsu; K Kokutei; H Yamashita; Mitsuru Sawa
[Aqueous protein concentration in diabetics. Report 5. Relationship between aqueous protein concentration and pathological findings of iridial vessels].
Nippon Ganka Gakkai zasshi 1992;96(8):1000-6.
1992: Shigeaki Kato; H Mano; R Kojima; Y Yoshizawa; Shoichi Masushige
Retinoid status and RARs expression.
Journal of nutritional science and vitaminology 1992;Spec No():477-80.
1990: Shigeaki Kato; H Nakamura
Cytoplasmic argyrophilic inclusions in neurons of pontine nuclei in patients with olivopontocerebellar atrophy: immunohistochemical and ultrastructural studies.
Acta neuropathologica 1990;79(6):584-94.
1990: Shigeaki Kato; S Itoh; Y Miura; H Naito; Tadashi Noguchi
Characterization of insulin receptors in primary cultures of quail (Coturnix coturnix japonica) oviduct cells. The level of insulin receptor is regulated by steroid and peptide hormones.
Comparative biochemistry and physiology. B, Comparative biochemistry 1990;97(4):783-91.
1990: Shigeaki Kato; H Nakamura
Presence of two different fibril subtypes in the Pick body: an immunoelectron microscopic study.
Acta neuropathologica 1990;81(2):125-9.
1989: Shigeaki Kato; S Ito; Tadashi Noguchi; H Naito
Effects of brefeldin A on the synthesis and secretion of egg white proteins in primary cultured oviduct cells of laying Japanese quail (Coturnix coturnix japonica).
Biochimica et biophysica acta 1989;991(1):36-43.
1989: T Oshika; Shigeaki Kato
Changes in aqueous flare and cells after mydriasis.
Japanese journal of ophthalmology 1989;33(3):271-8.
1989: H Nakamura; Shigeaki Kato; J Tanaka
Mitochondria covered with a net of parallel and latticed filaments in nigral neurons of monkeys with experimental parkinsonism.
Acta neuropathologica 1989;77(5):489-93.
1989: Shigeaki Kato; H Nakamura
Ultrastructural and ultracytochemical studies on the blood-brain barrier in chronic relapsing experimental allergic encephalomyelitis.
Acta neuropathologica 1989;77(5):455-64.
1989: T Oshika; Shigeaki Kato; H Funatsu
Quantitative assessment of aqueous flare intensity in diabetes.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1989;227(6):518-20.
1989: Shigeaki Kato; H Nakamura; E Otomo
Reappraisal of neurofibrillary tangles. Immunohistochemical, ultrastructural, and immunoelectron microscopical studies.
Acta neuropathologica 1989;77(3):258-66.
1988: Shigeaki Kato; S Ito; Y Miura; Tadashi Noguchi; H Naito
The effects of estrogen, insulin and dexamethasone on the synthesis and secretion of egg white proteins in primary cultured oviduct cells of laying Japanese quail (Coturnix coturnix japonica).
Comparative biochemistry and physiology. B, Comparative biochemistry 1988;89(1):79-83.
1988: J Tanaka; H Nakamura; S Honda; K Takada; Shigeaki Kato
Neuropathological study on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine of the crab-eating monkey.
Acta neuropathologica 1988;75(4):370-6.
1988: Shigeaki Kato; H Nakamura
Suppression of acute experimental allergic encephalomyelitis by synthetic serum thymic factor. Clinical, histopathological, and immunohistochemical studies.
Acta neuropathologica 1988;75(4):337-44.
1987: Shigeaki Kato; Tadashi Noguchi; H Naito
Secretion of egg white proteins in primary cultured oviduct cells of laying Japanese quail (Coturnix coturnix japonica).
Poultry science 1987;66(7):1208-16.