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Masahisa Katsuno

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Hideki Doi; Madoka Iida; Tetsuro Ishii; Masahisa Katsuno; Naohide Kondo; Shinjiro Matsumoto; Makoto Minamiyama; Yu Miyazaki; Qiang Qiang; Fumiaki Tanaka; Genki Tohnai; Eiji Warabi; Toru Yanagawa; Hiroaki Adachi; Gen Sobue
p62/SQSTM1 Differentially Removes the Toxic Mutant Androgen Receptor via Autophagy and Inclusion Formation in a Spinal and Bulbar Muscular Atrophy Mouse Model.
Kensuke Ikenaka; Yue-Mei Jiang; Masahisa Katsuno; Kaori Kawai; Tsubasa Kimata; Kyogo Kobayashi; Ikue Mori; Zhe Huang; Yohei Iguchi; Fumiaki Tanaka; Masahiro Waza; Gen Sobue
dnc-1/dynactin 1 knockdown disrupts transport of autophagosomes and induces motor neuron degeneration.
Hirotaka Nakanishi; Tomoko Noda; Fumiaki Tanaka; Hirohisa Watanabe; Manabu Doyu; Akifumi Fujikake; Masahisa Katsuno; Seigo Kimura; Haruki Koike; Koji Matsuo; Gen Sobue
Demographic features of Japanese patients with sporadic inclusion body myositis: a single-center referral experience.

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All Publications

2013: Hideki Doi; Madoka Iida; Tetsuro Ishii; Masahisa Katsuno; Naohide Kondo; Shinjiro Matsumoto; Makoto Minamiyama; Yu Miyazaki; Qiang Qiang; Fumiaki Tanaka; Genki Tohnai; Eiji Warabi; Toru Yanagawa; Hiroaki Adachi; Gen Sobue
p62/SQSTM1 Differentially Removes the Toxic Mutant Androgen Receptor via Autophagy and Inclusion Formation in a Spinal and Bulbar Muscular Atrophy Mouse Model.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013;33(18):7710-27.
2013: Kensuke Ikenaka; Yue-Mei Jiang; Masahisa Katsuno; Kaori Kawai; Tsubasa Kimata; Kyogo Kobayashi; Ikue Mori; Zhe Huang; Yohei Iguchi; Fumiaki Tanaka; Masahiro Waza; Gen Sobue
dnc-1/dynactin 1 knockdown disrupts transport of autophagosomes and induces motor neuron degeneration.
PloS one 2013;8(2):e54511.
2013: Hirotaka Nakanishi; Tomoko Noda; Fumiaki Tanaka; Hirohisa Watanabe; Manabu Doyu; Akifumi Fujikake; Masahisa Katsuno; Seigo Kimura; Haruki Koike; Koji Matsuo; Gen Sobue
Demographic features of Japanese patients with sporadic inclusion body myositis: a single-center referral experience.
Internal medicine (Tokyo, Japan) 2013;52(3):333-7.
2013: Naohide Kondo; Shinjiro Matsumoto; Makoto Minamiyama; Yu Miyazaki; Akira Nakai; Hideaki Nakatsuji; Hiroaki Adachi; Hideki Doi; Yusuke Fujioka; Madoka Iida; Shinsuke Ishigaki; Masahisa Katsuno; Fumiaki Tanaka; Genki Tohnai; Hirohisa Watanabe; Gen Sobue
Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration.
Nature communications 2013;4():1405.
2012: Masahisa Katsuno; Hiroaki Adachi; Haruhiko Banno; Keisuke Suzuki; Fumiaki Tanaka; Hirohisa Watanabe; Gen Sobue
Pathogenesis and therapy of spinal and bulbar muscular atrophy (SBMA).
Progress in neurobiology 2012;99(3):246-56.
2012: Tomoo Mano; Haruhiko Banno; Atsushi Hashizume; Masahisa Katsuno; Noriaki Suga; Keisuke Suzuki; Fumiaki Tanaka; Gen Sobue
Cross-sectional and longitudinal analysis of an oxidative stress biomarker for spinal and bulbar muscular atrophy.
Muscle & nerve 2012;46(5):692-7.
2012: Makoto Minamiyama; Yu Miyazaki; Fumiaki Tanaka; Hiroaki Adachi; Hideki Doi; Yusuke Fujioka; Madoka Iida; Shinsuke Ishigaki; Masahisa Katsuno; Naohide Kondo; Hiroki Kurihara; Shinjiro Matsumoto; Gen Sobue
Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by an expanded polyglutamine repeat tract.
Nature medicine 2012;18(10):1531-8.
2012: Masahisa Katsuno; Hiroaki Adachi; Haruhiko Banno; Atsushi Hashizume; Keisuke Suzuki; Fumiaki Tanaka; Gen Sobue
[109th Scientific Meeting of the Japanese Society of Internal Medicine: symposium: 2. Translational research and evidence-based medicine (EBM) in internal medicine in Japan, translational research; 1) Translational research on neurodegenerative diseases].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2012;101(9):2533-8.
2012: Atsushi Hashizume; Masahisa Katsuno; Tomoo Mano; Hiroaki Oe; Noriaki Suga; Keisuke Suzuki; Fumiaki Tanaka; Hirohisa Watanabe; Naoki Atsuta; Haruhiko Banno; Gen Sobue
Longitudinal changes of outcome measures in spinal and bulbar muscular atrophy.
Brain : a journal of neurology 2012;135(Pt 9):2838-48.
2012: Yu Miyazaki; Shin-ichi Muramatsu; Fumiaki Tanaka; Genki Tohnai; Hiroaki Adachi; Hideki Doi; Zhe Huang; Madoka Iida; Yue-Mei Jiang; Masahisa Katsuno; Naohide Kondo; Shinjiro Matsumoto; Makoto Minamiyama; Gen Sobue
Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2.
Nature medicine 2012;18(7):1136-41.
2012: Haruhiko Banno; Masahisa Katsuno; Keisuke Suzuki; Fumiaki Tanaka; Gen Sobue
Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy (SBMA).
Cell and tissue research 2012;349(1):313-20.
2012: Masahisa Katsuno; Hiroaki Adachi; Haruhiko Banno; Keisuke Suzuki; Fumiaki Tanaka; Gen Sobue
Molecular pathophysiology and disease-modifying therapies for spinal and bulbar muscular atrophy.
Archives of neurology 2012;69(4):436-40.
2012: Atsushi Hashizume; Masahisa Katsuno; Noriaki Suga; Keisuke Suzuki; Fumiaki Tanaka; Haruhiko Banno; Gen Sobue
Difference in chronological changes of outcome measures between untreated and placebo-treated patients of spinal and bulbar muscular atrophy.
Journal of neurology 2012;259(4):712-9.
2012: Keisuke Suzuki; Fumiaki Tanaka; Hiroaki Adachi; Haruhiko Banno; Masahisa Katsuno; Gen Sobue
[Disease-modifying therapy for spinal and bulbar muscular atrophy (SBMA)].
Brain and nerve = Shinkei kenkyū no shinpo 2012;64(3):237-44.
2012: Masahisa Katsuno; Fumiaki Tanaka; Gen Sobue
Perspectives on molecular targeted therapies and clinical trials for neurodegenerative diseases.
Journal of neurology, neurosurgery, and psychiatry 2012;83(3):329-35.
2012: Yohei Iguchi; Shinsuke Ishigaki; Masahisa Katsuno; Jun-ichi Niwa; Shinnosuke Takagi; Fumiaki Tanaka; Masato Hasegawa; Gen Sobue
Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43 linked to TDP-43 proteinopathies.
Neurobiology of disease 2012;45(3):862-70.
2012: Tetsuo Hama; Takashi Hara; Masaaki Hirayama; Masahisa Katsuno; Tomohiko Nakamura; Naoki Atsuta; Haruhiko Banno; Keisuke Suzuki; Fumiaki Tanaka; Gen Sobue
Discrimination of spinal and bulbar muscular atrophy from amyotrophic lateral sclerosis using sensory nerve action potentials.
Muscle & nerve 2012;45(2):169-74.
2012: S Kato; Masahisa Katsuno; Shinji Naganawa; J Senda; Naoki Atsuta; M Hirayama; M Ito; T Kaga; H Watanabe; G Sobue
Widespread cortical and subcortical brain atrophy in Parkinson's disease with excessive daytime sleepiness.
Journal of neurology 2012;259(2):318-26.
2012: Rieko Okada; Takashi Okada; Gen Sobue; Masahisa Katsuno; Hideyuki Muramoto; Akira Okada; Nobuyuki Hamajima
Severe brain atrophy in the elderly as a risk factor for lower respiratory tract infection.
Clinical interventions in aging 2012;7():481-7.
2012: Masahisa Katsuno; Hiroaki Adachi; Haruhiko Banno; Atsushi Hashizume; Keisuke Suzuki; Fumiaki Tanaka; Gen Sobue
[Anti-androgen therapy for spinal and bulbar muscular atrophy (SBMA)].
Rinshō shinkeigaku = Clinical neurology 2012;52(11):1207-9.
2012: R Katsumata; Masahisa Katsuno; Kaori Kawai; Hiroaki Adachi; Zhe Huang; Shinsuke Ishigaki; Jun Sone; Fumiaki Tanaka; Fumihiko Urano; Gen Sobue
c-Abl inhibition delays motor neuron degeneration in the G93A mouse, an animal model of amyotrophic lateral sclerosis.
PloS one 2012;7(9):e46185.
2012: Fumiaki Tanaka; Keisuke Suzuki; Hiroaki Adachi; Haruhiko Banno; Masahisa Katsuno; Gen Sobue
Current status of treatment of spinal and bulbar muscular atrophy.
Neural plasticity 2012;2012():369284.
2012: Kensuke Ikenaka; Shinsuke Ishigaki; Masahisa Katsuno; Kaori Kawai; Fumiaki Tanaka; Gen Sobue
Disruption of axonal transport in motor neuron diseases.
International journal of molecular sciences 2012;13(1):1225-38.
2011: Masahisa Katsuno; Hiroaki Adachi; Haruhiko Banno; Keisuke Suzuki; Fumiaki Tanaka; Gen Sobue
[TGF-beta signaling in neurodegenerative diseases].
Rinshō shinkeigaku = Clinical neurology 2011;51(11):982-5.
2011: Haruki Koike; Saori Morozumi; Yasumasa Okazaki; Yoshie Shimoyama; Yukio Ando; Masahiro Iijima; Hideya Kamei; Masahisa Katsuno; Yuichi Kawagashira; Tetsuya Kiuchi; Minoru Tomita; Mitsuharu Ueda; Hirohisa Watanabe; Gen Sobue
Systemic but asymptomatic transthyretin amyloidosis 8 years after domino liver transplantation.
Journal of neurology, neurosurgery, and psychiatry 2011;82(11):1287-90.
2011: A Hashizume; Masahisa Katsuno; K Matsuo; T Nagatani; Fumiaki Tanaka; Hirohisa Watanabe; Gen Sobue
Endoscopic third ventriculotomy improves parkinsonism following a ventriculo-peritoneal shunt in a patient with non-communicating hydrocephalus secondary to idiopathic aqueduct stenosis.
Journal of the neurological sciences 2011;309(1-2):148-50.
2011: Masahiro Iijima; Masahisa Katsuno; Haruki Koike; Gen Sobue
Polymorphism of transient axonal glycoprotein-1 in chronic inflammatory demyelinating polyneuropathy.
Journal of the peripheral nervous system : JPNS 2011;16 Suppl 1():52-5.
2011: Saori Morozumi; Haruki Koike; Minoru Tomita; Yuichi Kawagashira; Masahiro Iijima; Masahisa Katsuno; Naoki Hattori; Fumiaki Tanaka; Gen Sobue
Spatial distribution of nerve fiber pathology and vasculitis in microscopic polyangiitis-associated neuropathy.
Journal of neuropathology and experimental neurology 2011;70(5):340-8.
2011: Jun Sone; Fumiaki Tanaka; Haruki Koike; Akira Inukai; Masahisa Katsuno; Mari Yoshida; Hirohisa Watanabe; Gen Sobue
Skin biopsy is useful for the antemortem diagnosis of neuronal intranuclear inclusion disease.
Neurology 2011;76(16):1372-6.
2011: Yu Miyazaki; Haruki Koike; Mizuki Ito; Naoki Atsuta; Hirohisa Watanabe; Masahisa Katsuno; Susumu Kusunoki; Gen Sobue
Acute superficial sensory neuropathy with generalized anhidrosis, anosmia, and ageusia.
Muscle & nerve 2011;43(2):286-8.
2011: Haruhiko Banno; Masahisa Katsuno; Keisuke Suzuki; Gen Sobue
Dutasteride for spinal and bulbar muscular atrophy.
Lancet neurology 2011;10(2):113-5.
2011: Masahisa Katsuno; Hiroaki Adachi; Haruhiko Banno; Keisuke Suzuki; Fumiaki Tanaka; Gen Sobue
Transforming growth factor-β signaling in motor neuron diseases.
Current molecular medicine 2011;11(1):48-56.
2010: Yuichi Kawagashira; Haruki Koike; Minoru Tomita; Saori Morozumi; Masahiro Iijima; Tomohiko Nakamura; Masahisa Katsuno; Fumiaki Tanaka; Gen Sobue
Morphological progression of myelin abnormalities in IgM-monoclonal gammopathy of undetermined significance anti-myelin-associated glycoprotein neuropathy.
Journal of neuropathology and experimental neurology 2010;69(11):1143-57.
2010: Haruki Koike; Naoki Atsuta; Hiroaki Adachi; Masahiro Iijima; Masahisa Katsuno; Takeshi Yasuda; Yasuyo Fukada; Kenichi Yasui; Kenji Nakashima; Masahiro Horiuchi; Kazutaka Shiomi; Kazuhito Fukui; Shutaro Takashima; Yukari Morita; Kazumasa Kuniyoshi; Yasuhiro Hasegawa; Yasuhisa Toribe; Mitsugu Kajiura; Saoko Takeshita; Eiichiro Mukai; Gen Sobue
Clinicopathological features of acute autonomic and sensory neuropathy.
Brain : a journal of neurology 2010;133(10):2881-96.
2010: Hirohisa Watanabe; Mizuki Ito; Hiroshi Fukatsu; Jo Senda; Naoki Atsuta; Tomotsugu Kaga; Shigetaka Kato; Masahisa Katsuno; Fumiaki Tanaka; Masaaki Hirayama; Shinji Naganawa; Gen Sobue
Putaminal magnetic resonance imaging features at various magnetic field strengths in multiple system atrophy.
Movement disorders : official journal of the Movement Disorder Society 2010;25(12):1916-23.
2010: Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Yu Takeuchi; Motoshi Kawashima; Ichiro Yabe; Hidenao Sasaki; Masashi Aoki; Mitsuya Morita; Imaharu Nakano; Kazuaki Kanai; Shoichi Ito; Kinya Ishikawa; Hidehiro Mizusawa; Tomotaka Yamamoto; Shoji Tsuji; Kazuko Hasegawa; Takayoshi Shimohata; Masatoyo Nishizawa; Hiroaki Miyajima; Fumio Kanda; Yasuhiro Watanabe; Kenji Nakashima; Akira Tsujino; Taro Yamashita; Makoto Uchino; Yasushi Fujimoto; Fumiaki Tanaka; Gen Sobue
Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial.
Lancet neurology 2010;9(9):875-84.
2010: Yuichi Kawagashira; Naohide Kondo; Naoki Atsuta; Masahiro Iijima; Haruki Koike; Masahisa Katsuno; Fumiaki Tanaka; Susumu Kusunoki; Gen Sobue
IgM MGUS anti-MAG neuropathy with predominant muscle weakness and extensive muscle atrophy.
Muscle & nerve 2010;42(3):433-5.
2010: Keisuke Suzuki; Masahisa Katsuno; Haruhiko Banno; Yu Takeuchi; Motoshi Kawashima; Noriaki Suga; Atsushi Hashizume; Tetsuo Hama; Kei Uchida; Fumitada Yamashita; Tomohiko Nakamura; Masaaki Hirayama; Fumiaki Tanaka; Gen Sobue
The profile of motor unit number estimation (MUNE) in spinal and bulbar muscular atrophy.
Journal of neurology, neurosurgery, and psychiatry 2010;81(5):567-71.
2010: Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
Clinical features and molecular mechanisms of spinal and bulbar muscular atrophy (SBMA).
Advances in experimental medicine and biology 2010;685():64-74.
2010: Jun Sone; Jun-ichi Niwa; Kaori Kawai; Shinsuke Ishigaki; Shin-ichi Yamada; Hiroaki Adachi; Masahisa Katsuno; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis.
Journal of neuroscience research 2010;88(1):123-35.
2009: Haruki Koike; Yukio Ando; Mitsuharu Ueda; Yuichi Kawagashira; Masahiro Iijima; Junko Fujitake; Michiyuki Hayashi; Masahiko Yamamoto; Eiichiro Mukai; Tomohiko Nakamura; Masahisa Katsuno; Naoki Hattori; Gen Sobue
Distinct characteristics of amyloid deposits in early- and late-onset transthyretin Val30Met familial amyloid polyneuropathy.
Journal of the neurological sciences 2009;287(1-2):178-84.
2009: Hiroaki Adachi; Masahisa Katsuno; Masahiro Waza; Makoto Minamiyama; Fumiaki Tanaka; Gen Sobue
Heat shock proteins in neurodegenerative diseases: pathogenic roles and therapeutic implications.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2009;25(8):647-54.
2009: Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
[Molecular-targeted therapies for spinal and bulbar muscular atrophy].
Rinshō shinkeigaku = Clinical neurology 2009;49(11):917-20.
2009: Masahiro Iijima; M Tomita; S Morozumi; Y Kawagashira; T Nakamura; Haruki Koike; Masahisa Katsuno; Nobutaka Hattori; Fumiaki Tanaka; Masayuki Yamamoto; Gen Sobue
Single nucleotide polymorphism of TAG-1 influences IVIg responsiveness of Japanese patients with CIDP.
Neurology 2009;73(17):1348-52.
2009: Joe Senda; Mizuki Ito; Hirohisa Watanabe; Naoki Atsuta; Yoshinari Kawai; Masahisa Katsuno; Fumiaki Tanaka; Shinji Naganawa; Hiroshi Fukatsu; Gen Sobue
Correlation between pyramidal tract degeneration and widespread white matter involvement in amyotrophic lateral sclerosis: a study with tractography and diffusion-tensor imaging.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 2009;10(5-6):288-94.
2009: Yohei Iguchi; Masahisa Katsuno; Jun-ichi Niwa; Shin-ichi Yamada; Jun Sone; Masahiro Waza; Hiroaki Adachi; Fumiaki Tanaka; Koh-ichi Nagata; Nariko Arimura; Takashi Watanabe; Kozo Kaibuchi; Gen Sobue
TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases.
The Journal of biological chemistry 2009;284(33):22059-66.
2009: Haruhiko Banno; Masahisa Katsuno; Keisuke Suzuki; Yohei Iguchi; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
[Molecular-targeted therapy for motor neuron disease].
Brain and nerve = Shinkei kenkyū no shinpo 2009;61(8):891-900.
2009: Saori Morozumi; Yuichi Kawagashira; Masahiro Iijima; Haruki Koike; Naoki Hattori; Masahisa Katsuno; Fumiaki Tanaka; Gen Sobue
Intravenous immunoglobulin treatment for painful sensory neuropathy associated with Sjögren's syndrome.
Journal of the neurological sciences 2009;279(1-2):57-61.
2009: Haruhiko Banno; Masahisa Katsuno; Keisuke Suzuki; Fumiaki Tanaka; Gen Sobue
Neuropathology and therapeutic intervention in spinal and bulbar muscular atrophy.
International journal of molecular sciences 2009;10(3):1000-12.
2009: Masahisa Katsuno; Hiroaki Adachi; Gen Sobue
Getting a handle on Huntington's disease: the case for cholesterol.
Nature medicine 2009;15(3):253-4.
2009: Keisuke Tokui; Hiroaki Adachi; Masahiro Waza; Masahisa Katsuno; Makoto Minamiyama; Hideki Doi; Keiji Tanaka; Jun Hamazaki; Shigeo Murata; Fumiaki Tanaka; Gen Sobue
17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse.
Human molecular genetics 2009;18(5):898-910.
2009: Hirohisa Watanabe; Masaaki Hirayama; Akiko Noda; Masafumi Ito; Naoki Atsuta; J Senda; T Kaga; A Yamada; Masahisa Katsuno; T Niwa; Fumiaki Tanaka; Gen Sobue
B-type natriuretic peptide and cardiovalvulopathy in Parkinson disease with dopamine agonist.
Neurology 2009;72(7):621-6.
2009: Haruhiko Banno; Masahisa Katsuno; Keisuke Suzuki; Yu Takeuchi; Motoshi Kawashima; Noriaki Suga; Motoko Takamori; Mizuki Ito; Tomohiko Nakamura; Koji Matsuo; Shinichi Yamada; Yumiko Oki; Hiroaki Adachi; Makoto Minamiyama; Masahiro Waza; Naoki Atsuta; Hirohisa Watanabe; Yasushi Fujimoto; Tsutomu Nakashima; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy.
Annals of neurology 2009;65(2):140-50.
2009: Yuichi Kawagashira; Haruki Koike; Yumiko Oki; Naoki Hattori; Masahiro Iijima; Masahisa Katsuno; Fumiaki Tanaka; Hirohisa Watanabe; Gen Sobue
Intravenous immunoglobulin therapy in proximal diabetic neuropathy.
BMJ case reports 2009;2009():.
2008: Masahiro Iijima; Haruki Koike; Naoki Hattori; A Tamakoshi; Masahisa Katsuno; Fumiaki Tanaka; Masayuki Yamamoto; K Arimura; Gen Sobue
Prevalence and incidence rates of chronic inflammatory demyelinating polyneuropathy in the Japanese population.
Journal of neurology, neurosurgery, and psychiatry 2008;79(9):1040-3.
2008: Yu Takeuchi; Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Motoshi Kawashima; Naoki Atsuta; Mizuki Ito; Hirohisa Watanabe; Fumiaki Tanaka; Gen Sobue
Walking capacity evaluated by the 6-minute walk test in spinal and bulbar muscular atrophy.
Muscle & nerve 2008;38(2):964-71.
2008: Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Yu Takeuchi; Motoshi Kawashima; Fumiaki Tanaka; Hiroaki Adachi; Gen Sobue
Molecular genetics and biomarkers of polyglutamine diseases.
Current molecular medicine 2008;8(3):221-34.
2008: M Suenaga; Yoshinari Kawai; Hirohisa Watanabe; Naoki Atsuta; Mizuki Ito; Fumiaki Tanaka; Masahisa Katsuno; Hiroshi Fukatsu; Shinji Naganawa; Gen Sobue
Cognitive impairment in spinocerebellar ataxia type 6.
Journal of neurology, neurosurgery, and psychiatry 2008;79(5):496-9.
2008: Keisuke Suzuki; Masahisa Katsuno; Haruhiko Banno; Yu Takeuchi; Naoki Atsuta; Mizuki Ito; Hirohisa Watanabe; Fumitada Yamashita; Norio Hori; Tomohiko Nakamura; Masaaki Hirayama; Fumiaki Tanaka; Gen Sobue
CAG repeat size correlates to electrophysiological motor and sensory phenotypes in SBMA.
Brain : a journal of neurology 2008;131(Pt 1):229-39.
2007: Haruki Koike; Masahiro Iijima; Keiko Mori; Masahiko Yamamoto; Naoki Hattori; Masahisa Katsuno; Fumiaki Tanaka; Hirohisa Watanabe; Manabu Doyu; Hiroo Yoshikawa; Gen Sobue
Nonmyelinating Schwann cell involvement with well-preserved unmyelinated axons in Charcot-Marie-Tooth disease type 1A.
Journal of neuropathology and experimental neurology 2007;66(11):1027-36.
2007: Jun-ichi Niwa; Shin-ichi Yamada; Shinsuke Ishigaki; Jun Sone; Miho Takahashi; Masahisa Katsuno; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1.
The Journal of biological chemistry 2007;282(38):28087-95.
2007: Y Oki; Haruki Koike; Masahiro Iijima; Keiko Mori; Naoki Hattori; Masahisa Katsuno; T Nakamura; Masaaki Hirayama; Fumiaki Tanaka; M Shiraishi; Susumu Yazaki; Kazuya Nokura; Hiroko Yamamoto; Gen Sobue
Ataxic vs painful form of paraneoplastic neuropathy.
Neurology 2007;69(6):564-72.
2007: Y Kawagashira; Hirohisa Watanabe; Y Oki; Masahiro Iijima; Haruki Koike; Naoki Hattori; Masahisa Katsuno; Fumiaki Tanaka; Gen Sobue
Intravenous immunoglobulin therapy markedly ameliorates muscle weakness and severe pain in proximal diabetic neuropathy.
Journal of neurology, neurosurgery, and psychiatry 2007;78(8):899-901.
2007: Yue-Mei Jiang; Masahiko Yamamoto; Fumiaki Tanaka; Shinsuke Ishigaki; Masahisa Katsuno; Hiroaki Adachi; Jun-ichi Niwa; Manabu Doyu; Mari Yoshida; Yoshio Hashizume; Gen Sobue
Gene expressions specifically detected in motor neurons (dynactin 1, early growth response 3, acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to pathologic markers in sporadic amyotrophic lateral sclerosis.
Journal of neuropathology and experimental neurology 2007;66(7):617-27.
2007: Hiroaki Adachi; Masahiro Waza; Keisuke Tokui; Masahisa Katsuno; Makoto Minamiyama; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(19):5115-26.
2007: Masahisa Katsuno; Haruhiko Banno; Keisuke Suzuki; Yu Takeuchi; Gen Sobue
[Paradigm shift in clinical trials for neurodegenerative diseases].
Brain and nerve = Shinkei kenkyū no shinpo 2007;59(4):367-74.
2007: Hiroaki Adachi; Masahiro Waza; Masahisa Katsuno; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy.
Neuropathology and applied neurobiology 2007;33(2):135-51.
2006: Masahisa Katsuno; Hiroaki Adachi; Makoto Minamiyama; Masahiro Waza; Keisuke Tokui; Haruhiko Banno; Keisuke Suzuki; Yu Onoda; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
Reversible disruption of dynactin 1-mediated retrograde axonal transport in polyglutamine-induced motor neuron degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(47):12106-17.
2006: Masahiro Waza; Hiroaki Adachi; Masahisa Katsuno; Makoto Minamiyama; Fumiaki Tanaka; Gen Sobue
Alleviating neurodegeneration by an anticancer agent: an Hsp90 inhibitor (17-AAG).
Annals of the New York Academy of Sciences 2006;1086():21-34.
2006: Fumiaki Tanaka; Jun-ichi Niwa; Shinsuke Ishigaki; Masahisa Katsuno; Masahiro Waza; Masahiko Yamamoto; Manabu Doyu; Gen Sobue
Gene expression profiling toward understanding of ALS pathogenesis.
Annals of the New York Academy of Sciences 2006;1086():1-10.
2006: Masahiro Waza; Hiroaki Adachi; Masahisa Katsuno; Makoto Minamiyama; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
Modulation of Hsp90 function in neurodegenerative disorders: a molecular-targeted therapy against disease-causing protein.
Journal of molecular medicine (Berlin, Germany) 2006;84(8):635-46.
2006: Masahisa Katsuno; Hiroaki Adachi; Masahiro Waza; Haruhiko Banno; Keisuke Suzuki; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
Pathogenesis, animal models and therapeutics in spinal and bulbar muscular atrophy (SBMA).
Experimental neurology 2006;200(1):8-18.
2006: Naoki Atsuta; Hirohisa Watanabe; Mizuki Ito; Haruhiko Banno; Keisuke Suzuki; Masahisa Katsuno; Fumiaki Tanaka; Akiko Tamakoshi; Gen Sobue
Natural history of spinal and bulbar muscular atrophy (SBMA): a study of 223 Japanese patients.
Brain : a journal of neurology 2006;129(Pt 6):1446-55.
2006: Haruhiko Banno; Hiroaki Adachi; Masahisa Katsuno; Keisuke Suzuki; Naoki Atsuta; Hirohisa Watanabe; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
Mutant androgen receptor accumulation in spinal and bulbar muscular atrophy scrotal skin: a pathogenic marker.
Annals of neurology 2006;59(3):520-6.
2006: Makoto Sugiura; Haruki Koike; Masahiro Iijima; Keiko Mori; Naoki Hattori; Masahisa Katsuno; Fumiaki Tanaka; Gen Sobue
Clinicopathologic features of nonsystemic vasculitic neuropathy and microscopic polyangiitis-associated neuropathy: a comparative study.
Journal of the neurological sciences 2006;241(1-2):31-7.
2005: Masahisa Katsuno; Chen Sang; Hiroaki Adachi; Makoto Minamiyama; Masahiro Waza; Fumiaki Tanaka; Manabu Doyu; Gen Sobue
Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(46):16801-6.
2005: Keiko Mori; Masahiro Iijima; Haruki Koike; Naoki Hattori; Fumiaki Tanaka; Hirohisa Watanabe; Masahisa Katsuno; Asako Fujita; Ikuko Aiba; Akihiko Ogata; Toyokazu Saito; Kunihiko Asakura; Mari Yoshida; Masaaki Hirayama; Gen Sobue
The wide spectrum of clinical manifestations in Sjögren's syndrome-associated neuropathy.
Brain : a journal of neurology 2005;128(Pt 11):2518-34.
2005: Masahiro Waza; Hiroaki Adachi; Masahisa Katsuno; Makoto Minamiyama; Chen Sang; Fumiaki Tanaka; Akira Inukai; Manabu Doyu; Gen Sobue
17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration.
Nature medicine 2005;11(10):1088-95.
2005: Satoshi Suzuki; Shoichi Maruyama; Waichi Sato; Yoshiki Morita; Fumihiko Sato; Yusuke Miki; Sawako Kato; Masahisa Katsuno; Gen Sobue; Yukio Yuzawa; Seiichi Matsuo
Geranylgeranylacetone ameliorates ischemic acute renal failure via induction of Hsp70.
Kidney international 2005;67(6):2210-20.
2005: Masahiro Iijima; Masayuki Yamamoto; Masaaki Hirayama; Fumiaki Tanaka; Masahisa Katsuno; Keiko Mori; Haruki Koike; Naoki Hattori; K Arimura; M Nakagawa; H Yoshikawa; Kiyoshi Hayasaka; Osamu Onodera; M Baba; H Yasuda; T Saito; M Nakazato; K Nakashima; J Kira; R Kaji; N Oka; Gen Sobue
Clinical and electrophysiologic correlates of IVIg responsiveness in CIDP.
Neurology 2005;64(8):1471-5.
2005: Masahiko Yamamoto; Shinsuke Ishigaki; Masahisa Katsuno; Gen Sobue
[Motor neuron disease up-to date].
Nō to shinkei = Brain and nerve 2005;57(4):273-83.
2005: Hiroaki Adachi; Masahisa Katsuno; Makoto Minamiyama; Masahiro Waza; Chen Sang; Yuji Nakagomi; Yasushi Kobayashi; Fumiaki Tanaka; Manabu Doyu; Akira Inukai; Mari Yoshida; Yoshio Hashizume; Gen Sobue
Widespread nuclear and cytoplasmic accumulation of mutant androgen receptor in SBMA patients.
Brain : a journal of neurology 2005;128(Pt 3):659-70.
2005: Yue-Mei Jiang; Masahiko Yamamoto; Yasushi Kobayashi; Tsuyoshi Yoshihara; Yideng Liang; Shin-ichi Terao; Hideyuki Takeuchi; Shinsuke Ishigaki; Masahisa Katsuno; Hiroaki Adachi; Jun-ichi Niwa; Fumiaki Tanaka; Manabu Doyu; Mari Yoshida; Yoshio Hashizume; Gen Sobue
Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis.
Annals of neurology 2005;57(2):236-51.
2004: Hiroaki Adachi; Masahisa Katsuno; Gen Sobue
[Treatment of spinal and bulbar muscular atrophy].
Nō to shinkei = Brain and nerve 2004;56(9):772-9.
2004: Makoto Minamiyama; Masahisa Katsuno; Hiroaki Adachi; Masahiro Waza; Chen Sang; Yasushi Kobayashi; Fumiaki Tanaka; Manabu Doyu; Akira Inukai; Gen Sobue
Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy.
Human molecular genetics 2004;13(11):1183-92.
2004: Masahisa Katsuno; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
Spinal and bulbar muscular atrophy: ligand-dependent pathogenesis and therapeutic perspectives.
Journal of molecular medicine (Berlin, Germany) 2004;82(5):298-307.
2004: Masahisa Katsuno; Gen Sobue
Polyglutamine diminishes VEGF; passage to motor neuron death?
Neuron 2004;41(5):677-9.
2004: Hirohisa Watanabe; Hiroshi Fukatsu; Masahisa Katsuno; Makoto Sugiura; K Hamada; Y Okada; Masaaki Hirayama; T Ishigaki; Gen Sobue
Multiple regional 1H-MR spectroscopy in multiple system atrophy: NAA/Cr reduction in pontine base as a valuable diagnostic marker.
Journal of neurology, neurosurgery, and psychiatry 2004;75(1):103-9.
2003: Masahisa Katsuno; Hiroaki Adachi; Manabu Doyu; Makoto Minamiyama; Chen Sang; Yasushi Kobayashi; Akira Inukai; Gen Sobue
Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy.
Nature medicine 2003;9(6):768-73.
2003: Hiroaki Adachi; Masahisa Katsuno; Makoto Minamiyama; Chen Sang; Gerassimos Pagoulatos; Charalampos Angelidis; Moriaki Kusakabe; Atsushi Yoshiki; Yasushi Kobayashi; Manabu Doyu; Gen Sobue
Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(6):2203-11.
2003: Masahisa Katsuno; Hiroaki Adachi; Akira Inukai; Gen Sobue
Transgenic mouse models of spinal and bulbar muscular atrophy (SBMA).
Cytogenetic and genome research 2003;100(1-4):243-51.
2002: Masahisa Katsuno; Hiroaki Adachi; Akito Kume; Mei Li; Yuji Nakagomi; Hisayoshi Niwa; Chen Sang; Yasushi Kobayashi; Manabu Doyu; Gen Sobue
Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy.
Neuron 2002;35(5):843-54.