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Benita Katzenellenbogen

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Shoshana M Bartell; Ken L Chambliss; Li Han; Robert L Jilka; Benita S Katzenellenbogen; John A Katzenellenbogen; Ha-neui Kim; Sung Hoon Kim; Paula K Roberson; Philip W Shaul; Robert S Weinstein; Maria Almeida; Stavros C Manolagas
Non-nuclear-initiated actions of the estrogen receptor protect cortical bone mass.
Kyuri Kim; Zeynep Madak-Erdogan; Rosa Ventrella; Benita S Katzenellenbogen
A MicroRNA196a2* and TP63 circuit regulated by estrogen receptor-α and ERK2 that controls breast cancer proliferation and invasiveness properties.
Yuechao Zhao; Milan K Bagchi; Sunghee Park; Robert N Taylor; Benita S Katzenellenbogen
The coregulator, repressor of estrogen receptor activity (REA), is a crucial regulator of the timing and magnitude of uterine decidualization.

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2013: Shoshana M Bartell; Ken L Chambliss; Li Han; Robert L Jilka; Benita S Katzenellenbogen; John A Katzenellenbogen; Ha-neui Kim; Sung Hoon Kim; Paula K Roberson; Philip W Shaul; Robert S Weinstein; Maria Almeida; Stavros C Manolagas
Non-nuclear-initiated actions of the estrogen receptor protect cortical bone mass.
Molecular endocrinology (Baltimore, Md.) 2013;27(4):649-56.
2013: Kyuri Kim; Zeynep Madak-Erdogan; Rosa Ventrella; Benita S Katzenellenbogen
A MicroRNA196a2* and TP63 circuit regulated by estrogen receptor-α and ERK2 that controls breast cancer proliferation and invasiveness properties.
Hormones & cancer 2013;4(2):78-91.
2013: Yuechao Zhao; Milan K Bagchi; Sunghee Park; Robert N Taylor; Benita S Katzenellenbogen
The coregulator, repressor of estrogen receptor activity (REA), is a crucial regulator of the timing and magnitude of uterine decidualization.
Endocrinology 2013;154(3):1349-60.
2013: Anna Bergamaschi; Kristina Borgen; Jonna Frasor; Patricia Johnson; Kendrith Rowland; Adina Stanculescu; Elizabeth L Wiley; Benita S Katzenellenbogen
14-3-3ζ as a predictor of early time to recurrence and distant metastasis in hormone receptor-positive and -negative breast cancers.
Breast cancer research and treatment 2013;137(3):689-96.
2012: Sunghee Park; Seong-Eun Park; Jianming Xu; Sangyeon Yoon; Yuechao Zhao; Milan K Bagchi; Francesco J DeMayo; Lan Liao; John P Lydon; Bert W O'Malley; Benita S Katzenellenbogen
Uterine development and fertility are dependent on gene dosage of the nuclear receptor coregulator REA.
Endocrinology 2012;153(8):3982-94.
2012: Shweta Bhatt; Zhaojing Meng; Zhen Xiao; Benita S Katzenellenbogen
Phosphorylation by p38 mitogen-activated protein kinase promotes estrogen receptor α turnover and functional activity via the SCF(Skp2) proteasomal complex.
Molecular and cellular biology 2012;32(10):1928-43.
2012: Fabio Stossi; Z Madak-Erdoğan; Benita S Katzenellenbogen
Macrophage-elicited loss of estrogen receptor-α in breast cancer cells via involvement of MAPK and c-Jun at the ESR1 genomic locus.
Oncogene 2012;31(14):1825-34.
2012: Zeynep Madak-Erdogan; Benita S Katzenellenbogen
Aryl hydrocarbon receptor modulation of estrogen receptor α-mediated gene regulation by a multimeric chromatin complex involving the two receptors and the coregulator RIP140.
Toxicological sciences : an official journal of the Society of Toxicology 2012;125(2):401-11.
2012: A Bergamaschi; Benita S Katzenellenbogen
Tamoxifen downregulation of miR-451 increases 14-3-3ζ and promotes breast cancer cell survival and endocrine resistance.
Oncogene 2012;31(1):39-47.
2011: Sunghee Park; Jianming Xu; Sangyeon Yoon; Yuechao Zhao; Franco DeMayo; Lan Liao; John Lydon; Bert W O'Malley; Benita S Katzenellenbogen
Repressor of estrogen receptor activity (REA) is essential for mammary gland morphogenesis and functional activities: studies in conditional knockout mice.
Endocrinology 2011;152(11):4336-49.
2011: Joshua D Stender; Fabio Stossi; Daniel Barnett; Tze Howe Charn; Cory C Funk; Benita S Katzenellenbogen
The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells.
Molecular endocrinology (Baltimore, Md.) 2011;25(10):1699-709.
2011: Filippo Minutolo; Marco Macchia; Benita S Katzenellenbogen; John A Katzenellenbogen
Estrogen receptor β ligands: recent advances and biomedical applications.
Medicinal research reviews 2011;31(3):364-442.
2011: Bin He; Tae Hoon Kim; Ramakrishna Kommagani; Qin Feng; Rainer B Lanz; Jae Wook Jeong; Francesco J DeMayo; Benita S Katzenellenbogen; John P Lydon; Bert W O'Malley
Estrogen-regulated prohibitin is required for mouse uterine development and adult function.
Endocrinology 2011;152(3):1047-56.
2011: Anna Bergamaschi; Barbara L Christensen; Benita S Katzenellenbogen
Reversal of endocrine resistance in breast cancer: interrelationships among 14-3-3ζ, FOXM1, and a gene signature associated with mitosis.
Breast cancer research : BCR 2011;13(3):R70.
2011: Zeynep Madak-Erdogan; Mathieu Lupien; Fabio Stossi; Myles Brown; Benita S Katzenellenbogen
Genomic collaboration of estrogen receptor alpha and extracellular signal-regulated kinase 2 in regulating gene and proliferation programs.
Molecular and cellular biology 2011;31(1):226-36.
2010: Glenn M Marshall; S Gherardi; N Xu; Z Neiron; TN Trahair; C J Scarlett; D K Chang; P Y Liu; K Jankowski; N Iraci; Michelle Haber; Murray D Norris; J Keating; Eric Sekyere; G Jonquieres; F Stossi; Benita S Katzenellenbogen; Andrew V Biankin; Giovanni Perini; Tao Liu
Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects.
Oncogene 2010;29(44):5957-68.
2010: Jessica Santollo; Benita S Katzenellenbogen; John A Katzenellenbogen; Lisa A Eckel
Activation of ERα is necessary for estradiol's anorexigenic effect in female rats.
Hormones and behavior 2010;58(5):872-7.
2010: Joshua D Stender; Kyuri Kim; Tze Howe Charn; Barry S Komm; Ken C N Chang; W Lee Kraus; Christopher Benner; Christopher K Glass; Benita S Katzenellenbogen
Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation.
Molecular and cellular biology 2010;30(16):3943-55.
2010: Winifred P S Wong; Joseph Tiano; Suhuan Liu; Sylvia C Hewitt; Cedric Le May; Stéphane Dalle; John A Katzenellenbogen; Benita S Katzenellenbogen; Kenneth S Korach; Franck Mauvais-Jarvis
Extranuclear estrogen receptor-alpha stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(29):13057-62.
2010: Ken L Chambliss; Qian Wu; Sarah Oltmann; Eddy S Konaniah; Michihisa Umetani; Kenneth S Korach; Gail D Thomas; Chieko Mineo; Ivan S Yuhanna; Sung Hoon Kim; Zeynep Madak-Erdogan; Adriana Maggi; Sean P Dineen; Christina L Roland; David Y Hui; Rolf A Brekken; John A Katzenellenbogen; Benita S Katzenellenbogen; Philip W Shaul
Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice.
The Journal of clinical investigation 2010;120(7):2319-30.
2010: Karen J Kieser; Dong Wook Kim; Kathryn E Carlson; Benita S Katzenellenbogen; John A Katzenellenbogen
Characterization of the pharmacophore properties of novel selective estrogen receptor downregulators (SERDs).
Journal of medicinal chemistry 2010;53(8):3320-9.
2010: Tze Howe Charn; Edison Tak-Bun Liu; Edmund C Chang; Yew Kok Lee; John A Katzenellenbogen; Benita S Katzenellenbogen
Genome-wide dynamics of chromatin binding of estrogen receptors alpha and beta: mutual restriction and competitive site selection.
Molecular endocrinology (Baltimore, Md.) 2010;24(1):47-59.
2009: Michael Waibel; Karen J Kieser; Kathryn E Carlson; Fabio Stossi; Benita S Katzenellenbogen; John A Katzenellenbogen
Phenethyl pyridines with non-polar internal substituents as selective ligands for estrogen receptor beta.
European journal of medicinal chemistry 2009;44(9):3560-70.
2009: Michael Waibel; Meri De Angelis; Fabio Stossi; Karen J Kieser; Kathryn E Carlson; Benita S Katzenellenbogen; John A Katzenellenbogen
Bibenzyl- and stilbene-core compounds with non-polar linker atom substituents as selective ligands for estrogen receptor beta.
European journal of medicinal chemistry 2009;44(9):3412-24.
2009: Surojeet Sengupta; Rachel Schiff; Benita S Katzenellenbogen
Post-transcriptional regulation of chemokine receptor CXCR4 by estrogen in HER2 overexpressing, estrogen receptor-positive breast cancer cells.
Breast cancer research and treatment 2009;117(2):243-51.
2009: R J Hartmaier; M J E Walenkamp; A S Richter; J Wang; Benita S Katzenellenbogen; S Oesterreich; J M Wit
A case of premature thelarche with no central cause or genetic variants within the estrogen receptor signaling pathway.
Journal of pediatric endocrinology & metabolism : JPEM 2009;22(8):751-8.
2009: Fabio Stossi; Zeynep Madak-Erdogan; Benita S Katzenellenbogen
Estrogen receptor alpha represses transcription of early target genes via p300 and CtBP1.
Molecular and cellular biology 2009;29(7):1749-59.
2009: Yamini Achari; Ting Lu; Benita S Katzenellenbogen; David A Hart
Distinct roles for AF-1 and -2 of ER-alpha in regulation of MMP-13 promoter activity.
Biochimica et biophysica acta 2009;1792(3):211-20.
2009: Hai-Bing Zhou; Kathryn E Carlson; Fabio Stossi; Benita S Katzenellenbogen; John A Katzenellenbogen
Analogs of methyl-piperidinopyrazole (MPP): antiestrogens with estrogen receptor alpha selective activity.
Bioorganic & medicinal chemistry letters 2009;19(1):108-10.
2008: Shubin Sheng; Daniel Barnett; Benita S Katzenellenbogen
Differential estradiol and selective estrogen receptor modulator (SERM) regulation of Keratin 13 gene expression and its underlying mechanism in breast cancer cells.
Molecular and cellular endocrinology 2008;296(1-2):1-9.
2008: Zeynep Madak-Erdogan; Karen J Kieser; Sung Hoon Kim; Barry S Komm; John A Katzenellenbogen; Benita S Katzenellenbogen
Nuclear and extranuclear pathway inputs in the regulation of global gene expression by estrogen receptors.
Molecular endocrinology (Baltimore, Md.) 2008;22(9):2116-27.
2008: Rebecca Alyea; Stephanie E Laurence; Sung H Kim; Benita S Katzenellenbogen; John A Katzenellenbogen; Cheryl S Watson
The roles of membrane estrogen receptor subtypes in modulating dopamine transporters in PC-12 cells.
Journal of neurochemistry 2008;106(4):1525-33.
2008: Ramasamy Paulmurugan; Anobel Tamrazi; John A Katzenellenbogen; Benita S Katzenellenbogen; Sanjiv S Gambhir
A human estrogen receptor (ER)alpha mutation with differential responsiveness to nonsteroidal ligands: novel approaches for studying mechanism of ER action.
Molecular endocrinology (Baltimore, Md.) 2008;22(7):1552-64.
2008: Daniel Barnett; Shubin Sheng; Tze Howe Charn; Abdul Waheed; William S Sly; Chin-Yo Lin; Edison Liu; Benita S Katzenellenbogen
Estrogen receptor regulation of carbonic anhydrase XII through a distal enhancer in breast cancer.
Cancer research 2008;68(9):3505-15.
2008: Edmund C Chang; Tze Howe Charn; Sung-Hee Park; William G Helferich; Barry S Komm; John A Katzenellenbogen; Benita S Katzenellenbogen
Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding.
Molecular endocrinology (Baltimore, Md.) 2008;22(5):1032-43.
2008: Kendall W. Nettles; John B Bruning; German Gil; Jason Nowak; Sanjay K Sharma; Johnnie Hahm; Kristen Kulp; Richard B Hochberg; Haibing Zhou; John A Katzenellenbogen; Benita S Katzenellenbogen; Younchang Kim; Andrzej Joachmiak; Geoffrey L Greene
NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses.
Nature chemical biology 2008;4(4):241-7.
2008: Filippo Minutolo; R Bellini; Simone Bertini; Isabella Carboni; Annalina Lapucci; Letizia Pistolesi; Giovanni Prota; Simona Rapposelli; Francesca Solati; Tiziano Tuccinardi; Adriano Martinelli; Fabio Stossi; Kathryn E Carlson; Benita S Katzenellenbogen; John A Katzenellenbogen; Marco Macchia
Monoaryl-substituted salicylaldoximes as ligands for estrogen receptor beta.
Journal of medicinal chemistry 2008;51(5):1344-51.
2008: Bin He; Qin Feng; Atish Mukherjee; David M Lonard; Francesco J DeMayo; Benita S Katzenellenbogen; John P Lydon; Bert W O'Malley
A repressive role for prohibitin in estrogen signaling.
Molecular endocrinology (Baltimore, Md.) 2008;22(2):344-60.
2007: Joshua D Stender; Jonna Frasor; Barry S Komm; Ken C N Chang; W Lee Kraus; Benita S Katzenellenbogen
Estrogen-regulated gene networks in human breast cancer cells: involvement of E2F1 in the regulation of cell proliferation.
Molecular endocrinology (Baltimore, Md.) 2007;21(9):2112-23.
2007: P Mangala Gowri; Surojeet Sengupta; Suzanne Bertera; Benita S Katzenellenbogen
Lipin1 regulation by estrogen in uterus and liver: implications for diabetes and fertility.
Endocrinology 2007;148(8):3685-93.
2007: Hai-Bing Zhou; Kendall W. Nettles; John B Bruning; Younchang Kim; Andrzej Joachimiak; Sanjay Sharma; Kathryn E Carlson; Fabio Stossi; Benita S Katzenellenbogen; Geoffrey L Greene; John A Katzenellenbogen
Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands.
Chemistry & biology 2007;14(6):659-69.
2007: Chin-Yo Lin; Vinsensius B Vega; Jane S Thomsen; Tao Zhang; Say Li Kong; Min Xie; Kuo Ping Chiu; Leonard Lipovich; Daniel Barnett; Fabio Stossi; Ai Li Yeo; joshy george; Vladimir Kuznetsov; Yew Kok Lee; Tze Howe Charn; Nallasivam Palanisamy; Lance D Miller; Edwin Cheung; Benita S Katzenellenbogen; Yijun Ruan; Guillaume Bourque; Chia-Lin Wei; Edison Liu
Whole-genome cartography of estrogen receptor alpha binding sites.
PLoS genetics 2007;3(6):e87.
2007: Hai-Bing Zhou; Shubin Sheng; Dennis R Compton; Younchang Kim; Andrzej Joachimiak; Sanjay Sharma; Kathryn E Carlson; Benita S Katzenellenbogen; Kendall W. Nettles; Geoffrey L Greene; John A Katzenellenbogen
Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains.
Journal of medicinal chemistry 2007;50(2):399-403.
2006: Varsha S Likhite; Fabio Stossi; Kyuri Kim; Benita S Katzenellenbogen; John A Katzenellenbogen
Kinase-specific phosphorylation of the estrogen receptor changes receptor interactions with ligand, deoxyribonucleic acid, and coregulators associated with alterations in estrogen and tamoxifen activity.
Molecular endocrinology (Baltimore, Md.) 2006;20(12):3120-32.
2006: Paola Mussi; Lan Liao; Seong-Eun Park; Paolo Ciana; Stefano Di Giovine; Benita S Katzenellenbogen; Jianming Xu; Bert W O'Malley
Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(45):16716-21.
2006: Benita S Katzenellenbogen
In memoriam: Jack Gorski (1931-2006).
Molecular endocrinology (Baltimore, Md.) 2006;20(11):2611-2.
2006: Edmund C Chang; Jonna Frasor; Barry S Komm; Benita S Katzenellenbogen
Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells.
Endocrinology 2006;147(10):4831-42.
2006: William R Harrington; Surojeet Sengupta; Benita S Katzenellenbogen
Estrogen regulation of the glucuronidation enzyme UGT2B15 in estrogen receptor-positive breast cancer cells.
Endocrinology 2006;147(8):3843-50.
2006: Jonna Frasor; Edmund C Chang; Barry S Komm; Chin-Yo Lin; Vinsensius B Vega; Edison Liu; Lance D Miller; Johanna Smeds; Jonas Bergh; Benita S Katzenellenbogen
Gene expression preferentially regulated by tamoxifen in breast cancer cells and correlations with clinical outcome.
Cancer research 2006;66(14):7334-40.
2006: Fabio Stossi; Varsha S Likhite; John A Katzenellenbogen; Benita S Katzenellenbogen
Estrogen-occupied estrogen receptor represses cyclin G2 gene expression and recruits a repressor complex at the cyclin G2 promoter.
The Journal of biological chemistry 2006;281(24):16272-8.
2006: Vanessa Duong; Anne Licznar; Raphael Margueron; Nathalie Boulle; M Busson; M Lacroix; Benita S Katzenellenbogen; Vincent Cavaillès; Gwendal Lazennec
ERalpha and ERbeta expression and transcriptional activity are differentially regulated by HDAC inhibitors.
Oncogene 2006;25(12):1799-806.
2006: William R Harrington; Sung Hoon Kim; Cory C Funk; Zeynep Madak-Erdogan; Rachel Schiff; John A Katzenellenbogen; Benita S Katzenellenbogen
Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action.
Molecular endocrinology (Baltimore, Md.) 2006;20(3):491-502.
2006: Rajesh G Mishra; Frank Z Stanczyk; Kenneth A Burry; Suzanne Oparil; Benita S Katzenellenbogen; Michele L Nealen; John A Katzenellenbogen; Kent Hermsmeyer
Metabolite ligands of estrogen receptor-beta reduce primate coronary hyperreactivity.
American journal of physiology. Heart and circulatory physiology 2006;290(1):H295-303.
2005: Meri De Angelis; Fabio Stossi; Michael Waibel; Benita S Katzenellenbogen; John A Katzenellenbogen
Isocoumarins as estrogen receptor beta selective ligands: Isomers of isoflavone phytoestrogens and their metabolites.
Bioorganic & medicinal chemistry 2005;13(23):6529-42.
2005: Hai-Bing Zhou; John S Comninos; Fabio Stossi; Benita S Katzenellenbogen; John A Katzenellenbogen
Synthesis and evaluation of estrogen receptor ligands with bridged oxabicyclic cores containing a diarylethylene motif: estrogen antagonists of unusual structure.
Journal of medicinal chemistry 2005;48(23):7261-74.
2005: Jonna Frasor; Jeanne M Danes; Cory C Funk; Benita S Katzenellenbogen
Estrogen down-regulation of the corepressor N-CoR: mechanism and implications for estrogen derepression of N-CoR-regulated genes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(37):13153-7.
2005: Chenguang Wang; Saijun Fan; Zhiping Li; Maofu Fu; Mahadev Rao; Yongxian Ma; Michael P Lisanti; Chris Albanese; Benita S Katzenellenbogen; Peter J Kushner; Barbara Weber; Eliot M Rosen; Richard G Pestell
Cyclin D1 antagonizes BRCA1 repression of estrogen receptor alpha activity.
Cancer research 2005;65(15):6557-67.
2005: Vittoria Guerini; Daniela Sau; Eugenia Scaccianoce; PAOLA RUSMINI; Paolo Ciana; Stefano Di Giovine; Paolo G V Martini; Benita S Katzenellenbogen; Luciano Martini; Marcella Motta; Angelo Poletti
The androgen derivative 5alpha-androstane-3beta,17beta-diol inhibits prostate cancer cell migration through activation of the estrogen receptor beta subtype.
Cancer research 2005;65(12):5445-53.
2005: Deshanie Rai; Antonina Frolova; Jonna Frasor; Anne E Carpenter; Benita S Katzenellenbogen
Distinctive actions of membrane-targeted versus nuclear localized estrogen receptors in breast cancer cells.
Molecular endocrinology (Baltimore, Md.) 2005;19(6):1606-17.
2005: Morteza Aghmesheh; Lyndal Edwards; Christine L Clarke; Karen Byth; Benita S Katzenellenbogen; Pamela J Russell; Michael Friedlander; Katherine M Tucker; Anna de Fazio
Expression of steroid hormone receptors in BRCA1-associated ovarian carcinomas.
Gynecologic oncology 2005;97(1):16-25.
2005: Xing Zhao; Heather Lorenc; Heather Stephenson; Yunjiao Joy Wang; Dawn Witherspoon; Benita S Katzenellenbogen; Donald Pfaff; Nandini Vasudevan
Thyroid hormone can increase estrogen-mediated transcription from a consensus estrogen response element in neuroblastoma cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(13):4890-5.
2005: Seong-Eun Park; Jianming Xu; Antonina Frolova; Lan Liao; Bert W O'Malley; Benita S Katzenellenbogen
Genetic deletion of the repressor of estrogen receptor activity (REA) enhances the response to estrogen in target tissues in vivo.
Molecular and cellular biology 2005;25(5):1989-99.
2005: Meri De Angelis; Fabio Stossi; Kathryn A Carlson; Benita S Katzenellenbogen; John A Katzenellenbogen
Indazole estrogens: highly selective ligands for the estrogen receptor beta.
Journal of medicinal chemistry 2005;48(4):1132-44.
2005: Monica M Montano; Nicole R Bianco; Huayun Deng; Bryan M Wittmann; Laura C Chaplin; Benita S Katzenellenbogen
Estrogen receptor regulation of quinone reductase in breast cancer: implications for estrogen-induced breast tumor growth and therapeutic uses of tamoxifen.
Frontiers in bioscience : a journal and virtual library 2005;10():1440-61.
2004: Dennis R Compton; Shubin Sheng; Kathryn E Carlson; Natalie A Rebacz; In Young Lee; Benita S Katzenellenbogen; John A Katzenellenbogen
Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity.
Journal of medicinal chemistry 2004;47(24):5872-93.
2004: Zhilei Chen; Benita S Katzenellenbogen; John A Katzenellenbogen; Huimin Zhao
Directed evolution of human estrogen receptor variants with significantly enhanced androgen specificity and affinity.
The Journal of biological chemistry 2004;279(32):33855-64.
2004: Fabio Stossi; Daniel Barnett; Jonna Frasor; Barry S Komm; C Richard Lyttle; Benita S Katzenellenbogen
Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) alpha or ERbeta in human osteosarcoma cells: distinct and common target genes for these receptors.
Endocrinology 2004;145(7):3473-86.
2004: Houng-Wei Tsai; John A Katzenellenbogen; Benita S Katzenellenbogen; Margaret A Shupnik
Protein kinase A activation of estrogen receptor alpha transcription does not require proteasome activity and protects the receptor from ligand-mediated degradation.
Endocrinology 2004;145(6):2730-8.
2004: Frank Barletta; Chi-Wai Wong; Chris McNally; Barry S Komm; Benita S Katzenellenbogen; Boris J Cheskis
Characterization of the interactions of estrogen receptor and MNAR in the activation of cSrc.
Molecular endocrinology (Baltimore, Md.) 2004;18(5):1096-108.
2004: Rajeev S Muthyala; Young H Ju; Shubin Sheng; Lee D Williams; Daniel R Doerge; Benita S Katzenellenbogen; William G Helferich; John A Katzenellenbogen
Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta.
Bioorganic & medicinal chemistry 2004;12(6):1559-67.
2004: Mari Luz Acevedo; Kathleen C Lee; Joshua D Stender; Benita S Katzenellenbogen; W Lee Kraus
Selective recognition of distinct classes of coactivators by a ligand-inducible activation domain.
Molecular cell 2004;13(5):725-38.
2004: Jonna Frasor; Fabio Stossi; Jeanne M Danes; Barry S Komm; C Richard Lyttle; Benita S Katzenellenbogen
Selective estrogen receptor modulators: discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells.
Cancer research 2004;64(4):1522-33.
2004: Kendall W. Nettles; Jun Sun; James T Radek; Shubin Sheng; Alice L Rodriguez; John A Katzenellenbogen; Benita S Katzenellenbogen; Geoffrey L Greene
Allosteric control of ligand selectivity between estrogen receptors alpha and beta: implications for other nuclear receptors.
Molecular cell 2004;13(3):317-27.
2004: Benita S Katzenellenbogen; Jonna Frasor
Therapeutic targeting in the estrogen receptor hormonal pathway.
Seminars in oncology 2004;31(1 Suppl 3):28-38.
2003: Jonna Frasor; Jeanne M Danes; Barry S Komm; Ken C N Chang; C Richard Lyttle; Benita S Katzenellenbogen
Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype.
Endocrinology 2003;144(10):4562-74.
2003: Filippo Minutolo; Michela Antonello; Simone Bertini; Gabriella Ortore; Giorgio Placanica; Simona Rapposelli; Shubin Sheng; Kathryn E Carlson; Benita S Katzenellenbogen; John A Katzenellenbogen; Marco Macchia
Novel estrogen receptor ligands based on an anthranylaldoxime structure: role of the phenol-type pseudocycle in the binding process.
Journal of medicinal chemistry 2003;46(19):4032-42.
2003: William R Harrington; Shubin Sheng; Daniel Barnett; Larry N Petz; John A Katzenellenbogen; Benita S Katzenellenbogen
Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression.
Molecular and cellular endocrinology 2003;206(1-2):13-22.
2003: Jonna Frasor; Daniel Barnett; Jeanne M Danes; Rex Hess; Albert F Parlow; Benita S Katzenellenbogen
Response-specific and ligand dose-dependent modulation of estrogen receptor (ER) alpha activity by ERbeta in the uterus.
Endocrinology 2003;144(7):3159-66.
2003: Paolo G V Martini; Benita S Katzenellenbogen
Modulation of estrogen receptor activity by selective coregulators.
The Journal of steroid biochemistry and molecular biology 2003;85(2-5):117-22.
2003: Rajeev S Muthyala; Shubin Sheng; Kathryn E Carlson; Benita S Katzenellenbogen; John A Katzenellenbogen
Bridged bicyclic cores containing a 1,1-diarylethylene motif are high-affinity subtype-selective ligands for the estrogen receptor.
Journal of medicinal chemistry 2003;46(9):1589-602.
2003: Usha Ghosh; Deshanie Ganessunker; Viswajanani J Sattigeri; Kathryn E Carlson; Deborah J Mortensen; Benita S Katzenellenbogen; John A Katzenellenbogen
Estrogenic diazenes: heterocyclic non-steroidal estrogens of unusual structure with selectivity for estrogen receptor subtypes.
Bioorganic & medicinal chemistry 2003;11(4):629-57.
2003: Ramji R Rajendran; Anne C Nye; Jonna Frasor; Rashna D Balsara; Paolo G V Martini; Benita S Katzenellenbogen
Regulation of nuclear receptor transcriptional activity by a novel DEAD box RNA helicase (DP97).
The Journal of biological chemistry 2003;278(7):4628-38.
2003: Jun Sun; John A Katzenellenbogen; Huimin Zhao; Benita S Katzenellenbogen
DNA shuffling method for generating estrogen receptor alpha and beta chimeras in yeast.
BioTechniques 2003;34(2):278-80, 282, 284 passim.
2003: Jun Sun; Jerome Baudry; John A Katzenellenbogen; Benita S Katzenellenbogen
Molecular basis for the subtype discrimination of the estrogen receptor-beta-selective ligand, diarylpropionitrile.
Molecular endocrinology (Baltimore, Md.) 2003;17(2):247-58.
2003: James E Bowe; Xiao Feng Li; David Sugden; J A Katzenellenbogen; Benita S Katzenellenbogen; Kevin T O'Byrne
The effects of the phytoestrogen, coumestrol, on gonadotropin-releasing hormone (GnRH) mRNA expression in GT1-7 GnRH neurones.
Journal of neuroendocrinology 2003;15(2):105-8.
2002: Qing Zhou; Rong Nie; Gail S Prins; Philippa Saunders; Benita S Katzenellenbogen; Rex Allen Hess
Localization of androgen and estrogen receptors in adult male mouse reproductive tract.
Journal of andrology 2002;23(6):870-81.
2002: Heather A Harris; John A Katzenellenbogen; Benita S Katzenellenbogen
Characterization of the biological roles of the estrogen receptors, ERalpha and ERbeta, in estrogen target tissues in vivo through the use of an ERalpha-selective ligand.
Endocrinology 2002;143(11):4172-7.
2002: Tracy R Ediger; Seong-Eun Park; Benita S Katzenellenbogen
Estrogen receptor inducibility of the human Na+/H+ exchanger regulatory factor/ezrin-radixin-moesin binding protein 50 (NHE-RF/EBP50) gene involving multiple half-estrogen response elements.
Molecular endocrinology (Baltimore, Md.) 2002;16(8):1828-39.
2002: Anne C Nye; Ramji R Rajendran; David L Stenoien; Michael A Mancini; Benita S Katzenellenbogen; Andrew S Belmont
Alteration of large-scale chromatin structure by estrogen receptor.
Molecular and cellular biology 2002;22(10):3437-49.
2002: Andrew K Shiau; Danielle Barstad; James T Radek; Marvin J Meyers; Kendall W. Nettles; Benita S Katzenellenbogen; John A Katzenellenbogen; David A Agard; Geoffrey L Greene
Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.
Nature structural biology 2002;9(5):359-64.
2002: David J Rickard; Katrina M Waters; Terry J Ruesink; Sundeep Khosla; John A Katzenellenbogen; Benita S Katzenellenbogen; Lawrence B. Riggs; Thomas C Spelsberg
Estrogen receptor isoform-specific induction of progesterone receptors in human osteoblasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(4):580-92.
2002: Benita S Katzenellenbogen; John A Katzenellenbogen
Biomedicine. Defining the "S" in SERMs.
Science (New York, N.Y.) 2002;295(5564):2380-1.
2002: Andrés A Kowalski; Logan G Graddy; Dustin Vale-Cruz; Inho Choi; Benita S Katzenellenbogen; Frank A Simmen; Rosalia C M Simmen
Molecular cloning of porcine estrogen receptor-beta complementary DNAs and developmental expression in periimplantation embryos.
Biology of reproduction 2002;66(3):760-9.
2002: Jun Sun; Ying R Huang; William R Harrington; Shubin Sheng; John A Katzenellenbogen; Benita S Katzenellenbogen
Antagonists selective for estrogen receptor alpha.
Endocrinology 2002;143(3):941-7.
2001: Benita S Katzenellenbogen; Jun Sun; William R Harrington; DM Kraichely; Deshanie Ganessunker; John A Katzenellenbogen
Structure-function relationships in estrogen receptors and the characterization of novel selective estrogen receptor modulators with unique pharmacological profiles.
Annals of the New York Academy of Sciences 2001;949():6-15.
2001: Marvin J Meyers; Jun Sun; Kathryn E Carlson; G A Marriner; Benita S Katzenellenbogen; John A Katzenellenbogen
Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues.
Journal of medicinal chemistry 2001;44(24):4230-51.
2001: Qing Zhou; L Clarke; Rong Nie; Kay Carnes; Li-Wen Lai; Yeong-Hau H Lien; A Verkman; Dennis B Lubahn; J S Fisher; Benita S Katzenellenbogen; Rex Allen Hess
Estrogen action and male fertility: roles of the sodium/hydrogen exchanger-3 and fluid reabsorption in reproductive tract function.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):14132-7.
2001: DS Mortensen; Alice L Rodriguez; Kathryn E Carlson; Jun Sun; Benita S Katzenellenbogen; John A Katzenellenbogen
Synthesis and biological evaluation of a novel series of furans: ligands selective for estrogen receptor alpha.
Journal of medicinal chemistry 2001;44(23):3838-48.
2001: DS Mortensen; Alice L Rodriguez; Jun Sun; Benita S Katzenellenbogen; John A Katzenellenbogen
Furans with basic side chains: synthesis and biological evaluation of a novel series of antagonists with selectivity for the estrogen receptor alpha.
Bioorganic & medicinal chemistry letters 2001;11(18):2521-4.
2001: Katrina M Waters; David J Rickard; Lawrence B. Riggs; Sundeep Khosla; J A Katzenellenbogen; Benita S Katzenellenbogen; J Moore; Thomas C Spelsberg
Estrogen regulation of human osteoblast function is determined by the stage of differentiation and the estrogen receptor isoform.
Journal of cellular biochemistry 2001;83(3):448-62.
2001: Gail S Prins; Lynn Birch; J F Couse; I Choi; Benita S Katzenellenbogen; K S Korach
Estrogen imprinting of the developing prostate gland is mediated through stromal estrogen receptor alpha: studies with alphaERKO and betaERKO mice.
Cancer research 2001;61(16):6089-97.
2001: Simone Nuedling; Richard H Karas; Michael Mendelsohn; J A Katzenellenbogen; Benita S Katzenellenbogen; Rainer Meyer; Hans Vetter; Christian Grohé
Activation of estrogen receptor beta is a prerequisite for estrogen-dependent upregulation of nitric oxide synthases in neonatal rat cardiac myocytes.
FEBS letters 2001;502(3):103-8.
2001: Paolo G V Martini; Benita S Katzenellenbogen
Regulation of prothymosin alpha gene expression by estrogen in estrogen receptor-containing breast cancer cells via upstream half-palindromic estrogen response element motifs.
Endocrinology 2001;142(8):3493-501.
2001: I Choi; Chemyong Ko; Ok-Kyong Park-Sarge; Rong Nie; Rex Allen Hess; C Graves; Benita S Katzenellenbogen
Human estrogen receptor beta-specific monoclonal antibodies: characterization and use in studies of estrogen receptor beta protein expression in reproductive tissues.
Molecular and cellular endocrinology 2001;181(1-2):139-50.
2001: G Lazennec; J A Thomas; Benita S Katzenellenbogen
Involvement of cyclic AMP response element binding protein (CREB) and estrogen receptor phosphorylation in the synergistic activation of the estrogen receptor by estradiol and protein kinase activators.
The Journal of steroid biochemistry and molecular biology 2001;77(4-5):193-203.
2001: Chenguang Wang; Maofu Fu; Ruth Hogue Angeletti; Linda Siconolfi-Baez; Anne T Reutens; Chris Albanese; Michael P Lisanti; Benita S Katzenellenbogen; S Kato; Torsten A Hopp; Suzanne A W Fuqua; Gabriela N Lopez; Peter J Kushner; Richard G Pestell
Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity.
The Journal of biological chemistry 2001;276(21):18375-83.
2001: S Wissink; Bart van der Burg; Benita S Katzenellenbogen; Paul T van der Saag
Synergistic activation of the serotonin-1A receptor by nuclear factor-kappa B and estrogen.
Molecular endocrinology (Baltimore, Md.) 2001;15(4):543-52.
2001: Stavroula Kousteni; Teresita Bellido; Lilian Plotkin; Charles A O'Brien; Donald L Bodenner; L Han; K Han; G B DiGregorio; J A Katzenellenbogen; Benita S Katzenellenbogen; Paula K Roberson; Robert S Weinstein; Robert L Jilka; Stavros C Manolagas
Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity.
Cell 2001;104(5):719-30.
2001: R Tedesco; J A Thomas; Benita S Katzenellenbogen; John A Katzenellenbogen
The estrogen receptor: a structure-based approach to the design of new specific hormone-receptor combinations.
Chemistry & biology 2001;8(3):277-87.
2001: SR Stauffer; Y R Huang; Zachary D Aron; CJ Coletta; Jun Sun; Benita S Katzenellenbogen; John A Katzenellenbogen
Triarylpyrazoles with basic side chains: development of pyrazole-based estrogen receptor antagonists.
Bioorganic & medicinal chemistry 2001;9(1):151-61.
2000: SR Stauffer; CJ Coletta; R Tedesco; G Nishiguchi; K Carlson; Jun Sun; Benita S Katzenellenbogen; John A Katzenellenbogen
Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists.
Journal of medicinal chemistry 2000;43(26):4934-47.
2000: Mary Beth Martin; Thomas F Franke; Gerald E Stoica; P Chambon; Benita S Katzenellenbogen; Bogdan A Stoica; M S McLemore; Susan Olivo; Adriana Stoica
A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I.
Endocrinology 2000;141(12):4503-11.
2000: Benita S Katzenellenbogen; I Choi; R Delage-Mourroux; Tracy R Ediger; Paolo G V Martini; MM Montano; Jun Sun; KE Weis; John A Katzenellenbogen
Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology.
The Journal of steroid biochemistry and molecular biology 2000;74(5):279-85.
2000: R Delage-Mourroux; Paolo G V Martini; I Choi; DM Kraichely; J Hoeksema; Benita S Katzenellenbogen
Analysis of estrogen receptor interaction with a repressor of estrogen receptor activity (REA) and the regulation of estrogen receptor transcriptional activity by REA.
The Journal of biological chemistry 2000;275(46):35848-56.
2000: Young H Ju; K E Carlson; J Sun; Dorothy R Pathak; Benita S Katzenellenbogen; John A Katzenellenbogen; William G Helferich
Estrogenic effects of extracts from cabbage, fermented cabbage, and acidified brussels sprouts on growth and gene expression of estrogen-dependent human breast cancer (MCF-7) cells.
Journal of agricultural and food chemistry 2000;48(10):4628-34.
2000: DM Kraichely; Jun Sun; John A Katzenellenbogen; Benita S Katzenellenbogen
Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-alpha and estrogen receptor-beta: correlations with biological character and distinct differences among SRC coactivator family members.
Endocrinology 2000;141(10):3534-45.
2000: Paolo G V Martini; R Delage-Mourroux; DM Kraichely; Benita S Katzenellenbogen
Prothymosin alpha selectively enhances estrogen receptor transcriptional activity by interacting with a repressor of estrogen receptor activity.
Molecular and cellular biology 2000;20(17):6224-32.
2000: I Choi; L J Gudas; Benita S Katzenellenbogen
Regulation of keratin 19 gene expression by estrogen in human breast cancer cells and identification of the estrogen responsive gene region.
Molecular and cellular endocrinology 2000;164(1-2):225-37.
2000: SR Stauffer; Jun Sun; Benita S Katzenellenbogen; John A Katzenellenbogen
Acyclic amides as estrogen receptor ligands: synthesis, binding, activity and receptor interaction.
Bioorganic & medicinal chemistry 2000;8(6):1293-316.
2000: G de Haan; S Chusacultanachai; Chengjian Mao; Benita S Katzenellenbogen; David J Shapiro
Estrogen receptor-KRAB chimeras are potent ligand-dependent repressors of estrogen-regulated gene expression.
The Journal of biological chemistry 2000;275(18):13493-501.
2000: Adriana Stoica; Benita S Katzenellenbogen; Mary Beth Martin
Activation of estrogen receptor-alpha by the heavy metal cadmium.
Molecular endocrinology (Baltimore, Md.) 2000;14(4):545-53.
2000: Benita S Katzenellenbogen; John A Katzenellenbogen
Estrogen receptor transcription and transactivation: Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer.
Breast cancer research : BCR 2000;2(5):335-44.
2000: Benita S Katzenellenbogen; MM Montano; Tracy R Ediger; Jun Sun; K Ekena; G Lazennec; Paolo G V Martini; EM McInerney; R Delage-Mourroux; KE Weis; John A Katzenellenbogen
Estrogen receptors: selective ligands, partners, and distinctive pharmacology.
Recent progress in hormone research 2000;55():163-93; discussion 194-5.
2000: Benita S Katzenellenbogen
Mechanisms of action and cross-talk between estrogen receptor and progesterone receptor pathways.
Journal of the Society for Gynecologic Investigation 2000;7(1 Suppl):S33-7.
1999: A Schlegel; C Wang; Benita S Katzenellenbogen; Richard G Pestell; M P Lisanti
Caveolin-1 potentiates estrogen receptor alpha (ERalpha) signaling. caveolin-1 drives ligand-independent nuclear translocation and activation of ERalpha.
The Journal of biological chemistry 1999;274(47):33551-6.
1999: Arvin Gee; Kathryn E Carlson; P G Martini; Benita S Katzenellenbogen; John A Katzenellenbogen
Coactivator peptides have a differential stabilizing effect on the binding of estrogens and antiestrogens with the estrogen receptor.
Molecular endocrinology (Baltimore, Md.) 1999;13(11):1912-23.
1999: Paul Webb; Phuong Nguyen; Cathleen D Valentine; Gabriela N Lopez; G R Kwok; EM McInerney; Benita S Katzenellenbogen; E Enmark; J A Gustafsson; S Nilsson; Peter J Kushner
The estrogen receptor enhances AP-1 activity by two distinct mechanisms with different requirements for receptor transactivation functions.
Molecular endocrinology (Baltimore, Md.) 1999;13(10):1672-85.
1999: S Chusacultanachai; KA Glenn; A O Rodriguez; Erik K Read; Jeffrey F Gardner; Benita S Katzenellenbogen; David J Shapiro
Analysis of estrogen response element binding by genetically selected steroid receptor DNA binding domain mutants exhibiting altered specificity and enhanced affinity.
The Journal of biological chemistry 1999;274(33):23591-8.
1999: Marvin J Meyers; Jun Sun; Kathryn E Carlson; Benita S Katzenellenbogen; John A Katzenellenbogen
Estrogen receptor subtype-selective ligands: asymmetric synthesis and biological evaluation of cis- and trans-5,11-dialkyl- 5,6,11, 12-tetrahydrochrysenes.
Journal of medicinal chemistry 1999;42(13):2456-68.
1999: Tracy R Ediger; W Lee Kraus; Edward J Weinman; Benita S Katzenellenbogen
Estrogen receptor regulation of the Na+/H+ exchange regulatory factor.
Endocrinology 1999;140(7):2976-82.
1999: MM Montano; K Ekena; R Delage-Mourroux; W Chang; Paolo G V Martini; Benita S Katzenellenbogen
An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6947-52.
1999: G Lazennec; J L Alcorn; Benita S Katzenellenbogen
Adenovirus-mediated delivery of a dominant negative estrogen receptor gene abrogates estrogen-stimulated gene expression and breast cancer cell proliferation.
Molecular endocrinology (Baltimore, Md.) 1999;13(6):969-80.
1999: G Lazennec; Benita S Katzenellenbogen
Expression of human estrogen receptor using an efficient adenoviral gene delivery system is able to restore hormone-dependent features to estrogen receptor-negative breast carcinoma cells.
Molecular and cellular endocrinology 1999;149(1-2):93-105.
1999: Jun Sun; Marvin J Meyers; B E Fink; R Rajendran; John A Katzenellenbogen; Benita S Katzenellenbogen
Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta.
Endocrinology 1999;140(2):800-4.
1998: EM McInerney; KE Weis; Jun Sun; S Mosselman; Benita S Katzenellenbogen
Transcription activation by the human estrogen receptor subtype beta (ER beta) studied with ER beta and ER alpha receptor chimeras.
Endocrinology 1998;139(11):4513-22.
1998: Paul Webb; Phuong Nguyen; J Shinsako; C Anderson; Weijun Feng; M P Nguyen; D Chen; S M Huang; S Subramanian; E McKinerney; Benita S Katzenellenbogen; Michael R Stallcup; Peter J Kushner
Estrogen receptor activation function 1 works by binding p160 coactivator proteins.
Molecular endocrinology (Baltimore, Md.) 1998;12(10):1605-18.
1998: M M Montano; Anil K Jaiswal; Benita S Katzenellenbogen
Transcriptional regulation of the human quinone reductase gene by antiestrogen-liganded estrogen receptor-alpha and estrogen receptor-beta.
The Journal of biological chemistry 1998;273(39):25443-9.
1998: J W Clemens; Rebecca L Robker; W Lee Kraus; Benita S Katzenellenbogen; JoAnne S Richards
Hormone induction of progesterone receptor (PR) messenger ribonucleic acid and activation of PR promoter regions in ovarian granulosa cells: evidence for a role of cyclic adenosine 3',5'-monophosphate but not estradiol.
Molecular endocrinology (Baltimore, Md.) 1998;12(8):1201-14.
1998: K Ekena; John A Katzenellenbogen; Benita S Katzenellenbogen
Determinants of ligand specificity of estrogen receptor-alpha: estrogen versus androgen discrimination.
The Journal of biological chemistry 1998;273(2):693-9.
1997: Kathryn E Carlson; I Choi; Arvin Gee; Benita S Katzenellenbogen; John A Katzenellenbogen
Altered ligand binding properties and enhanced stability of a constitutively active estrogen receptor: evidence that an open pocket conformation is required for ligand interaction.
Biochemistry 1997;36(48):14897-905.
1997: W Lee Kraus; KE Weis; Benita S Katzenellenbogen
Determinants for the repression of estrogen receptor transcriptional activity by ligand-occupied progestin receptors.
The Journal of steroid biochemistry and molecular biology 1997;63(4-6):175-88.
1997: G Lazennec; Tracy R Ediger; Larry N Petz; Carol Curtis; Benita S Katzenellenbogen
Mechanistic aspects of estrogen receptor activation probed with constitutively active estrogen receptors: correlations with DNA and coregulator interactions and receptor conformational changes.
Molecular endocrinology (Baltimore, Md.) 1997;11(9):1375-86.
1997: Sigrid Aliau; D El Garrouj; Aziz Yasri; Benita S Katzenellenbogen; Jean-Louis Borgna
17 alpha (haloacetamidoalkyl) estradiols alkylate the human estrogen receptor at cysteine residues 417 and 530.
Biochemistry 1997;36(19):5861-7.
1997: Benita S Katzenellenbogen; MM Montano; K Ekena; M E Herman; EM McInerney
William L. McGuire Memorial Lecture. Antiestrogens: mechanisms of action and resistance in breast cancer.
Breast cancer research and treatment 1997;44(1):23-38.
1997: MM Montano; Benita S Katzenellenbogen
The quinone reductase gene: a unique estrogen receptor-regulated gene that is activated by antiestrogens.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2581-6.
1997: M M Montano; W Lee Kraus; Benita S Katzenellenbogen
Identification of a novel transferable cis element in the promoter of an estrogen-responsive gene that modulates sensitivity to hormone and antihormone.
Molecular endocrinology (Baltimore, Md.) 1997;11(3):330-41.
1997: Benita S Katzenellenbogen; K S Korach
A new actor in the estrogen receptor drama--enter ER-beta.
Endocrinology 1997;138(3):861-2.
1997: K Ekena; KE Weis; John A Katzenellenbogen; Benita S Katzenellenbogen
Different residues of the human estrogen receptor are involved in the recognition of structurally diverse estrogens and antiestrogens.
The Journal of biological chemistry 1997;272(8):5069-75.
1996: EM McInerney; B A Ince; David J Shapiro; Benita S Katzenellenbogen
A transcriptionally active estrogen receptor mutant is a novel type of dominant negative inhibitor of estrogen action.
Molecular endocrinology (Baltimore, Md.) 1996;10(12):1519-26.
1996: K E Weis; K Ekena; J A Thomas; G Lazennec; Benita S Katzenellenbogen
Constitutively active human estrogen receptors containing amino acid substitutions for tyrosine 537 in the receptor protein.
Molecular endocrinology (Baltimore, Md.) 1996;10(11):1388-98.
1996: M E Herman; Benita S Katzenellenbogen
Response-specific antiestrogen resistance in a newly characterized MCF-7 human breast cancer cell line resulting from long-term exposure to trans-hydroxytamoxifen.
The Journal of steroid biochemistry and molecular biology 1996;59(2):121-34.
1996: EM McInerney; Benita S Katzenellenbogen
Different regions in activation function-1 of the human estrogen receptor required for antiestrogen- and estradiol-dependent transcription activation.
The Journal of biological chemistry 1996;271(39):24172-8.
1996: EM McInerney; M J Tsai; Bert W O'Malley; Benita S Katzenellenbogen
Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10069-73.
1996: K Ekena; K E Weis; John A Katzenellenbogen; Benita S Katzenellenbogen
Identification of amino acids in the hormone binding domain of the human estrogen receptor important in estrogen binding.
The Journal of biological chemistry 1996;271(33):20053-9.
1996: J A Katzenellenbogen; Benita S Katzenellenbogen
Nuclear hormone receptors: ligand-activated regulators of transcription and diverse cell responses.
Chemistry & biology 1996;3(7):529-36.
1996: MM Montano; K Ekena; K D Krueger; A L Keller; Benita S Katzenellenbogen
Human estrogen receptor ligand activity inversion mutants: receptors that interpret antiestrogens as estrogens and estrogens as antiestrogens and discriminate among different antiestrogens.
Molecular endocrinology (Baltimore, Md.) 1996;10(3):230-42.
1996: John A Katzenellenbogen; Bert W O'Malley; Benita S Katzenellenbogen
Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones.
Molecular endocrinology (Baltimore, Md.) 1996;10(2):119-31.
1996: Benita S Katzenellenbogen
Estrogen receptors: bioactivities and interactions with cell signaling pathways.
Biology of reproduction 1996;54(2):287-93.
1995: D J Schodin; Y Zhuang; David J Shapiro; Benita S Katzenellenbogen
Analysis of mechanisms that determine dominant negative estrogen receptor effectiveness.
The Journal of biological chemistry 1995;270(52):31163-71.
1995: W Lee Kraus; E M McInerney; Benita S Katzenellenbogen
Ligand-dependent, transcriptionally productive association of the amino- and carboxyl-terminal regions of a steroid hormone nuclear receptor.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12314-8.
1995: B A Ince; D J Schodin; David J Shapiro; Benita S Katzenellenbogen
Repression of endogenous estrogen receptor activity in MCF-7 human breast cancer cells by dominant negative estrogen receptors.
Endocrinology 1995;136(8):3194-9.
1995: MM Montano; V Müller; A Trobaugh; Benita S Katzenellenbogen
The carboxy-terminal F domain of the human estrogen receptor: role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists.
Molecular endocrinology (Baltimore, Md.) 1995;9(7):814-25.
1995: Robert I Nicholson; J M W Gee; DL Manning; A E Wakeling; M M Montano; Benita S Katzenellenbogen
Responses to pure antiestrogens (ICI 164384, ICI 182780) in estrogen-sensitive and -resistant experimental and clinical breast cancer.
Annals of the New York Academy of Sciences 1995;761():148-63.
1995: Benita S Katzenellenbogen; MM Montano; P Le Goff; D J Schodin; W Lee Kraus; B Bhardwaj; N Fujimoto
Antiestrogens: mechanisms and actions in target cells.
The Journal of steroid biochemistry and molecular biology 1995;53(1-6):387-93.
1995: W Lee Kraus; K E Weis; Benita S Katzenellenbogen
Inhibitory cross-talk between steroid hormone receptors: differential targeting of estrogen receptor in the repression of its transcriptional activity by agonist- and antagonist-occupied progestin receptors.
Molecular and cellular biology 1995;15(4):1847-57.
1995: Y Zhuang; Benita S Katzenellenbogen; David J Shapiro
Estrogen receptor mutants which do not bind 17 beta-estradiol dimerize and bind to the estrogen response element in vivo.
Molecular endocrinology (Baltimore, Md.) 1995;9(4):457-66.
1994: M E Herman; Benita S Katzenellenbogen
Alterations in transforming growth factor-alpha and -beta production and cell responsiveness during the progression of MCF-7 human breast cancer cells to estrogen-autonomous growth.
Cancer research 1994;54(22):5867-74.
1994: B A Ince; MM Montano; Benita S Katzenellenbogen
Activation of transcriptionally inactive human estrogen receptors by cyclic adenosine 3',5'-monophosphate and ligands including antiestrogens.
Molecular endocrinology (Baltimore, Md.) 1994;8(10):1397-406.
1994: S M Aronica; W Lee Kraus; Benita S Katzenellenbogen
Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(18):8517-21.
1994: W Lee Kraus; MM Montano; Benita S Katzenellenbogen
Identification of multiple, widely spaced estrogen-responsive regions in the rat progesterone receptor gene.
Molecular endocrinology (Baltimore, Md.) 1994;8(8):952-69.
1994: K E Bergmann; C H Wooge; Kathryn E Carlson; Benita S Katzenellenbogen; John A Katzenellenbogen
Bivalent ligands as probes of estrogen receptor action.
The Journal of steroid biochemistry and molecular biology 1994;49(2-3):139-52.
1994: N Fujimoto; Benita S Katzenellenbogen
Alteration in the agonist/antagonist balance of antiestrogens by activation of protein kinase A signaling pathways in breast cancer cells: antiestrogen selectivity and promoter dependence.
Molecular endocrinology (Baltimore, Md.) 1994;8(3):296-304.
1994: P Le Goff; MM Montano; D J Schodin; Benita S Katzenellenbogen
Phosphorylation of the human estrogen receptor. Identification of hormone-regulated sites and examination of their influence on transcriptional activity.
The Journal of biological chemistry 1994;269(6):4458-66.
1994: H Cho; S M Aronica; Benita S Katzenellenbogen
Regulation of progesterone receptor gene expression in MCF-7 breast cancer cells: a comparison of the effects of cyclic adenosine 3',5'-monophosphate, estradiol, insulin-like growth factor-I, and serum factors.
Endocrinology 1994;134(2):658-64.
1993: Benita S Katzenellenbogen; B Bhardwaj; H Fang; B A Ince; F Pakdel; J C Reese; D Schodin; C K Wrenn
Hormone binding and transcription activation by estrogen receptors: analyses using mammalian and yeast systems.
The Journal of steroid biochemistry and molecular biology 1993;47(1-6):39-48.
1993: F Pakdel; P Le Goff; Benita S Katzenellenbogen
An assessment of the role of domain F and PEST sequences in estrogen receptor half-life and bioactivity.
The Journal of steroid biochemistry and molecular biology 1993;46(6):663-72.
1993: W Lee Kraus; MM Montano; Benita S Katzenellenbogen
Cloning of the rat progesterone receptor gene 5'-region and identification of two functionally distinct promoters.
Molecular endocrinology (Baltimore, Md.) 1993;7(12):1603-16.
1993: C K Wrenn; Benita S Katzenellenbogen
Structure-function analysis of the hormone binding domain of the human estrogen receptor by region-specific mutagenesis and phenotypic screening in yeast.
The Journal of biological chemistry 1993;268(32):24089-98.
1993: F Pakdel; J C Reese; Benita S Katzenellenbogen
Identification of charged residues in an N-terminal portion of the hormone-binding domain of the human estrogen receptor important in transcriptional activity of the receptor.
Molecular endocrinology (Baltimore, Md.) 1993;7(11):1408-17.
1993: B A Ince; Y Zhuang; C K Wrenn; David J Shapiro; Benita S Katzenellenbogen
Powerful dominant negative mutants of the human estrogen receptor.
The Journal of biological chemistry 1993;268(19):14026-32.
1993: W Lee Kraus; Benita S Katzenellenbogen
Regulation of progesterone receptor gene expression and growth in the rat uterus: modulation of estrogen actions by progesterone and sex steroid hormone antagonists.
Endocrinology 1993;132(6):2371-9.
1993: S M Aronica; Benita S Katzenellenbogen
Stimulation of estrogen receptor-mediated transcription and alteration in the phosphorylation state of the rat uterine estrogen receptor by estrogen, cyclic adenosine monophosphate, and insulin-like growth factor-I.
Molecular endocrinology (Baltimore, Md.) 1993;7(6):743-52.
1993: H Cho; Benita S Katzenellenbogen
Synergistic activation of estrogen receptor-mediated transcription by estradiol and protein kinase activators.
Molecular endocrinology (Baltimore, Md.) 1993;7(3):441-52.
1993: Benita S Katzenellenbogen; H Fang; B A Ince; F Pakdel; J C Reese; C H Wooge; C K Wrenn
William L. McGuire Memorial Symposium. Estrogen receptors: ligand discrimination and antiestrogen action.
Breast cancer research and treatment 1993;27(1-2):17-26.
1992: J C Reese; C H Wooge; Benita S Katzenellenbogen
Identification of two cysteines closely positioned in the ligand-binding pocket of the human estrogen receptor: roles in ligand binding and transcriptional activation.
Molecular endocrinology (Baltimore, Md.) 1992;6(12):2160-6.
1992: J C Reese; Benita S Katzenellenbogen
Examination of the DNA-binding ability of estrogen receptor in whole cells: implications for hormone-independent transactivation and the actions of antiestrogens.
Molecular and cellular biology 1992;12(10):4531-8.
1992: C H Wooge; G M Nilsson; A Heierson; D P McDonnell; Benita S Katzenellenbogen
Structural requirements for high affinity ligand binding by estrogen receptors: a comparative analysis of truncated and full length estrogen receptors expressed in bacteria, yeast, and mammalian cells.
Molecular endocrinology (Baltimore, Md.) 1992;6(6):861-9.
1992: J C Reese; Benita S Katzenellenbogen
Characterization of a temperature-sensitive mutation in the hormone binding domain of the human estrogen receptor. Studies in cell extracts and intact cells and their implications for hormone-dependent transcriptional activation.
The Journal of biological chemistry 1992;267(14):9868-73.
1992: F Pakdel; Benita S Katzenellenbogen
Human estrogen receptor mutants with altered estrogen and antiestrogen ligand discrimination.
The Journal of biological chemistry 1992;267(5):3429-37.
1992: L D Read; Benita S Katzenellenbogen
Characterization and regulation of estrogen and progesterone receptors in breast cancer.
Cancer treatment and research 1992;61():277-99.
1991: J C Reese; Benita S Katzenellenbogen
Differential DNA-binding abilities of estrogen receptor occupied with two classes of antiestrogens: studies using human estrogen receptor overexpressed in mammalian cells.
Nucleic acids research 1991;19(23):6595-602.
1991: Benita S Katzenellenbogen
Antiestrogen resistance: mechanisms by which breast cancer cells undermine the effectiveness of endocrine therapy.
Journal of the National Cancer Institute 1991;83(20):1434-5.
1991: H S Cho; P A NG; Benita S Katzenellenbogen
Differential regulation of gene expression by estrogen in estrogen growth-independent and -dependent MCF-7 human breast cancer cell sublines.
Molecular endocrinology (Baltimore, Md.) 1991;5(9):1323-30.
1991: J C Reese; Benita S Katzenellenbogen
Mutagenesis of cysteines in the hormone binding domain of the human estrogen receptor. Alterations in binding and transcriptional activation by covalently and reversibly attaching ligands.
The Journal of biological chemistry 1991;266(17):10880-7.
1991: S M Aronica; Benita S Katzenellenbogen
Progesterone receptor regulation in uterine cells: stimulation by estrogen, cyclic adenosine 3',5'-monophosphate, and insulin-like growth factor I and suppression by antiestrogens and protein kinase inhibitors.
Endocrinology 1991;128(4):2045-52.
1991: K G Pinney; Kathryn E Carlson; Benita S Katzenellenbogen; John A Katzenellenbogen
Efficient and selective photoaffinity labeling of the estrogen receptor using two nonsteroidal ligands that embody aryl azide or tetrafluoroaryl azide photoreactive functions.
Biochemistry 1991;30(9):2421-31.
1990: C K Wrenn; Benita S Katzenellenbogen
Cross-linking of estrogen receptor to chromatin in intact MCF-7 human breast cancer cells: optimization and effect of ligand.
Molecular endocrinology (Baltimore, Md.) 1990;4(11):1647-54.
1990: L D Read; D Keith; Dennis J Slamon; Benita S Katzenellenbogen
Hormonal modulation of HER-2/neu protooncogene messenger ribonucleic acid and p185 protein expression in human breast cancer cell lines.
Cancer research 1990;50(13):3947-51.
1990: Benita S Katzenellenbogen; M J Norman
Multihormonal regulation of the progesterone receptor in MCF-7 human breast cancer cells: interrelationships among insulin/insulin-like growth factor-I, serum, and estrogen.
Endocrinology 1990;126(2):891-8.
1990: Benita S Katzenellenbogen; Carol Curtis; L D Read
Estrogen regulation of proliferation and hormonal modulation of estrogen and progesterone receptor biosynthesis and degradation in target cells.
Progress in clinical and biological research 1990;322():201-11.
1990: Benita S Katzenellenbogen
A tribute to Jack Gorski: estrogen receptor model builder and scientific friend to many.
Progress in clinical and biological research 1990;322():1-16.
1989: K W Harlow; D N Smith; J A Katzenellenbogen; G L Greene; Benita S Katzenellenbogen
Identification of cysteine 530 as the covalent attachment site of an affinity-labeling estrogen (ketononestrol aziridine) and antiestrogen (tamoxifen aziridine) in the human estrogen receptor.
The Journal of biological chemistry 1989;264(29):17476-85.
1989: Robert Clarke; Nils Brünner; Benita S Katzenellenbogen; Erik W Thompson; M J Norman; C Koppi; Soonmyung Paik; Marc Lippman; Robert B Dickson
Progression of human breast cancer cells from hormone-dependent to hormone-independent growth both in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3649-53.
1989: L D Read; Geoffrey L Greene; Benita S Katzenellenbogen
Regulation of estrogen receptor messenger ribonucleic acid and protein levels in human breast cancer cell lines by sex steroid hormones, their antagonists, and growth factors.
Molecular endocrinology (Baltimore, Md.) 1989;3(2):295-304.
1988: Christine A. Weaver; P A Springer; Benita S Katzenellenbogen
Regulation of pS2 gene expression by affinity labeling and reversibly binding estrogens and antiestrogens: comparison of effects on the native gene and on pS2-chloramphenicol acetyltransferase fusion genes transfected into MCF-7 human breast cancer cells.
Molecular endocrinology (Baltimore, Md.) 1988;2(10):936-45.
1988: R D Bindal; Kathryn E Carlson; Benita S Katzenellenbogen; John A Katzenellenbogen
Lipophilic impurities, not phenolsulfonphthalein, account for the estrogenic activity in commercial preparations of phenol red.
Journal of steroid biochemistry 1988;31(3):287-93.
1988: J F Elliston; Benita S Katzenellenbogen
Comparative analysis of estrogen receptors covalently labeled with an estrogen and an antiestrogen in several estrogen target cells as studied by limited proteolysis.
Journal of steroid biochemistry 1988;29(6):559-69.
1988: Carol Curtis; Benita S Katzenellenbogen
Progesterone receptor regulation in T47D human breast cancer cells: analysis by density labeling of progesterone receptor synthesis and degradation and their modulation by progestin.
Endocrinology 1988;122(4):1532-40.
1988: L D Read; C E Snider; J S Miller; Geoffrey L Greene; Benita S Katzenellenbogen
Ligand-modulated regulation of progesterone receptor messenger ribonucleic acid and protein in human breast cancer cell lines.
Molecular endocrinology (Baltimore, Md.) 1988;2(3):263-71.
1988: Carol Curtis; Geoffrey L Greene; Bert W O'Malley; Benita S Katzenellenbogen
Regulation of progesterone receptor messenger ribonucleic acid and protein levels in MCF-7 cells by estradiol: analysis of estrogen's effect on progesterone receptor synthesis and degradation.
Endocrinology 1988;122(3):935-44.
1988: W F Mangel; D L Toledo; A M Nardulli; G C Reiner; M J Norman; Benita S Katzenellenbogen
Plasminogen activators in human breast cancer cell lines: hormonal regulation and properties.
Journal of steroid biochemistry 1988;30(1-6):79-88.
1987: Benita S Katzenellenbogen; K L Kendra; M J Norman; Y Berthois
Proliferation, hormonal responsiveness, and estrogen receptor content of MCF-7 human breast cancer cells grown in the short-term and long-term absence of estrogens.
Cancer research 1987;47(16):4355-60.
1987: J F Elliston; J A Zablocki; Benita S Katzenellenbogen; J A Katzenellenbogen
Ketononestrol aziridine, an agonistic estrogen receptor affinity label: study of its bioactivity and estrogen receptor covalent labeling.
Endocrinology 1987;121(2):667-76.
1987: K L Kendra; Benita S Katzenellenbogen
An evaluation of the involvement of polyamines in modulating MCF-7 human breast cancer cell proliferation and progesterone receptor levels by estrogen and antiestrogen.
Journal of steroid biochemistry 1987;28(2):123-8.
1987: J A Zablocki; J A Katzenellenbogen; K E Carlson; M J Norman; Benita S Katzenellenbogen
Estrogenic affinity labels: synthesis, irreversible receptor binding, and bioactivity of aziridine-substituted hexestrol derivatives.
Journal of medicinal chemistry 1987;30(5):829-38.
1987: Benita S Katzenellenbogen; J F Elliston; F J Monsma; P A Springer; Y S Ziegler; G L Greene
Structural analysis of covalently labeled estrogen receptors by limited proteolysis and monoclonal antibody reactivity.
Biochemistry 1987;26(8):2364-73.
1987: Y Y Sheen; Benita S Katzenellenbogen
Antiestrogen stimulation of the production of a 37,000 molecular weight secreted protein and estrogen stimulation of the production of a 32,000 molecular weight secreted protein in MCF-7 human breast cancer cells.
Endocrinology 1987;120(3):1140-51.
1987: T W Toney; Benita S Katzenellenbogen
An evaluation of the interactions of antiestrogens with pituitary and striatal dopamine receptors.
Journal of receptor research 1987;7(5):695-712.
1986: T W Toney; Benita S Katzenellenbogen
Antiestrogen action in the medial basal hypothalamus and pituitary of immature female rats: insights concerning relationships among estrogen, dopamine, and prolactin.
Endocrinology 1986;119(6):2661-9.
1986: A M Nardulli; Benita S Katzenellenbogen
Dynamics of estrogen receptor turnover in uterine cells in vitro and in uteri in vivo.
Endocrinology 1986;119(5):2038-46.
1986: F G Salituro; Kathryn E Carlson; J F Elliston; Benita S Katzenellenbogen; John A Katzenellenbogen
[125I]iododesethyl tamoxifen aziridine: synthesis and covalent labeling of the estrogen receptor with an iodine-labeled affinity label.
Steroids 1986;48(5-6):287-313.
1986: A Mullick; Benita S Katzenellenbogen
Progesterone receptor synthesis and degradation in MCF-7 human breast cancer cells as studied by dense amino acid incorporation. Evidence for a non-hormone binding receptor precursor.
The Journal of biological chemistry 1986;261(28):13236-46.
1986: Y Berthois; J A Katzenellenbogen; Benita S Katzenellenbogen
Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(8):2496-500.
1986: G C Reiner; Benita S Katzenellenbogen
Characterization of estrogen and progesterone receptors and the dissociated regulation of growth and progesterone receptor stimulation by estrogen in MDA-MB-134 human breast cancer cells.
Cancer research 1986;46(3):1124-31.
1986: A Mullick; Benita S Katzenellenbogen
Antiprogestin-receptor complexes: differences in the interaction of the antiprogestin RU38,486 and the progestin R5020 with the progesterone receptor of human breast cancer cells.
Biochemical and biophysical research communications 1986;135(1):90-7.
1986: L L Wei; Benita S Katzenellenbogen; D W Robertson; D M Simpson; J A Katzenellenbogen
Nitrosourea and nitrosocarbamate derivatives of the antiestrogen tamoxifen as potential estrogen receptor-mediated cytotoxic agents in human breast cancer cells.
Breast cancer research and treatment 1986;7(2):77-90.
1985: L L Wei; W F Mangel; Benita S Katzenellenbogen
Biological activities of tamoxifen aziridine, an antiestrogen-based affinity label for the estrogen receptor, in vivo and in vitro.
Journal of steroid biochemistry 1985;23(6A):875-81.
1985: Y Y Sheen; T S Ruh; W F Mangel; Benita S Katzenellenbogen
Antiestrogenic potency and binding characteristics of the triphenylethylene H1285 in MCF-7 human breast cancer cells.
Cancer research 1985;45(9):4192-9.
1985: Y Y Sheen; D M Simpson; Benita S Katzenellenbogen
An evaluation of the role of antiestrogen-binding sites in mediating the growth modulatory effects of antiestrogens: studies using t-butylphenoxyethyl diethylamine, a compound lacking affinity for the estrogen receptor.
Endocrinology 1985;117(2):561-4.
1985: M A Miller; A Mullick; G L Greene; Benita S Katzenellenbogen
Characterization of the subunit nature of nuclear estrogen receptors by chemical cross-linking and dense amino acid labeling.
Endocrinology 1985;117(2):515-22.
1985: J A Katzenellenbogen; K E Carlson; Benita S Katzenellenbogen
Facile geometric isomerization of phenolic non-steroidal estrogens and antiestrogens: limitations to the interpretation of experiments characterizing the activity of individual isomers.
Journal of steroid biochemistry 1985;22(5):589-96.
1985: Benita S Katzenellenbogen; M A Miller; A Mullick; Y Y Sheen
Antiestrogen action in breast cancer cells: modulation of proliferation and protein synthesis, and interaction with estrogen receptors and additional antiestrogen binding sites.
Breast cancer research and treatment 1985;5(3):231-43.
1984: M A Miller; Marc Lippman; Benita S Katzenellenbogen
Antiestrogen binding in antiestrogen growth-resistant estrogen-responsive clonal variants of MCF-7 human breast cancer cells.
Cancer research 1984;44(11):5038-45.
1984: Ellen A Rorke; K L Kendra; Benita S Katzenellenbogen
Relationships among uterine growth, ornithine decarboxylase activity and polyamine levels: studies with estradiol and antiestrogens.
Molecular and cellular endocrinology 1984;38(1):31-8.
1984: Ellen A Rorke; Benita S Katzenellenbogen
Dissociated regulation of growth and ornithine decarboxylase activity by estrogen in the rat uterus.
Biochemical and biophysical research communications 1984;122(3):1186-93.
1984: F J Monsma; Benita S Katzenellenbogen; M A Miller; Y S Ziegler; J A Katzenellenbogen
Characterization of the estrogen receptor and its dynamics in MCF-7 human breast cancer cells using a covalently attaching antiestrogen.
Endocrinology 1984;115(1):143-53.
1984: G C Reiner; Benita S Katzenellenbogen; R D Bindal; John A Katzenellenbogen
Biological activity and receptor binding of a strongly interacting estrogen in human breast cancer cells.
Cancer research 1984;44(6):2302-8.
1984: Benita S Katzenellenbogen
Biology and receptor interactions of estriol and estriol derivatives in vitro and in vivo.
Journal of steroid biochemistry 1984;20(4B):1033-7.
1984: Richard L Eckert; A Mullick; Ellen A Rorke; Benita S Katzenellenbogen
Estrogen receptor synthesis and turnover in MCF-7 breast cancer cells measured by a density shift technique.
Endocrinology 1984;114(2):629-37.
1984: M A Miller; G L Greene; Benita S Katzenellenbogen
Estrogen receptor transformation in MCF-7 breast cancer cells: characterization by immunochemical and sedimentation analyses.
Endocrinology 1984;114(1):296-8.
1984: Benita S Katzenellenbogen; M J Norman; Richard L Eckert; Stuart Peltz; W F Mangel
Bioactivities, estrogen receptor interactions, and plasminogen activator-inducing activities of tamoxifen and hydroxy-tamoxifen isomers in MCF-7 human breast cancer cells.
Cancer research 1984;44(1):112-9.
1984: J A Katzenellenbogen; Benita S Katzenellenbogen
Affinity labeling of receptors for steroid and thyroid hormones.
Vitamins and hormones 1984;41():213-74.
1983: Benita S Katzenellenbogen; M A Miller; Richard L Eckert; K Sudo
Antiestrogen pharmacology and mechanism of action.
Journal of steroid biochemistry 1983;19(1A):59-68.
1983: M A Miller; Benita S Katzenellenbogen
Characterization and quantitation of antiestrogen binding sites in estrogen receptor-positive and -negative human breast cancer cell lines.
Cancer research 1983;43(7):3094-100.
1983: John A Katzenellenbogen; K E Carlson; D F Heiman; D W Robertson; L L Wei; Benita S Katzenellenbogen
Efficient and highly selective covalent labeling of the estrogen receptor with [3H]tamoxifen aziridine.
The Journal of biological chemistry 1983;258(6):3487-95.
1983: Stuart Peltz; Benita S Katzenellenbogen; M A Kneifel; W F Mangel
Plasminogen activators in tissues of the immature and estrogen-stimulated rat uterus and in uterine luminal fluid: characterization and properties.
Endocrinology 1983;112(3):890-7.
1983: K Sudo; F J Monsma; Benita S Katzenellenbogen
Antiestrogen-binding sites distinct from the estrogen receptor: subecellular localization, ligand specificity, and distribution in tissues of the rat.
Endocrinology 1983;112(2):425-34.
1983: Richard L Eckert; Benita S Katzenellenbogen
Modulation of progestin binding activity in cultured human breast carcinoma cells: the effect of serum type and concentration.
Journal of receptor research 1983;3(5):599-621.
1982: R M Hersey; Judith Weisz; Benita S Katzenellenbogen
Estrogenic potency, receptor interactions, and metabolism of catechol estrogens in the immature rat uterus in vitro.
Endocrinology 1982;111(3):896-903.
1982: Richard L Eckert; Benita S Katzenellenbogen
Physical properties of estrogen receptor complexes in MCF-7 human breast cancer cells. Differences with anti-estrogen and estrogen.
The Journal of biological chemistry 1982;257(15):8840-6.
1982: M A Kneifel; S P Leytus; E Fletcher; T Weber; W F Mangel; Benita S Katzenellenbogen
Uterine plasminogen activator activity: modulation by steroid hormones.
Endocrinology 1982;111(2):493-9.
1982: Edward Pavlik; Benita S Katzenellenbogen
The intranuclear distribution of rat uterine estrogen receptors determined after nuclease treatment and chromatin fractionation.
Molecular and cellular endocrinology 1982;26(1-2):201-16.
1982: D W Robertson; J A Katzenellenbogen; J R Hayes; Benita S Katzenellenbogen
Antiestrogen basicity--activity relationships: a comparison of the estrogen receptor binding and antiuterotrophic potencies of several analogues of (Z)-1,2-diphenyl-1-[4-[2-(dimethylamino)ethoxy]phenyl]-1-butene (tamoxifen, Nolvadex) having altered basicity.
Journal of medicinal chemistry 1982;25(2):167-71.
1982: D W Robertson; J A Katzenellenbogen; D J Long; Ellen A Rorke; Benita S Katzenellenbogen
Tamoxifen antiestrogens. A comparison of the activity, pharmacokinetics, and metabolic activation of the cis and trans isomers of tamoxifen.
Journal of steroid biochemistry 1982;16(1):1-13.
1982: Richard L Eckert; Benita S Katzenellenbogen
Effects of estrogens and antiestrogens on estrogen receptor dynamics and the induction of progesterone receptor in MCF-7 human breast cancer cells.
Cancer research 1982;42(1):139-44.
1981: Benita S Katzenellenbogen; Ellen A Rorke; Richard L Eckert
Mechanisms of estrogen and antiestrogen action in mammary cancer.
Journal of steroid biochemistry 1981;15():219-29.
1981: D W Robertson; L L Wei; J R Hayes; K E Carlson; J A Katzenellenbogen; Benita S Katzenellenbogen
Tamoxifen aziridines: effective inactivators of the estrogen receptor.
Endocrinology 1981;109(4):1298-300.
1981: Richard L Eckert; Benita S Katzenellenbogen
Human endometrial cells in primary tissue culture: modulation of the progesterone receptor level by natural and synthetic estrogens in vitro.
The Journal of clinical endocrinology and metabolism 1981;52(4):699-708.
1981: Ellen A Rorke; Benita S Katzenellenbogen
Antitumor activities and estrogen receptor interactions of the metabolites of the antiestrogens C1628 and U23,469 in the 7,12-dimethylbenz(a)anthracene-induced rat mammary tumor system.
Cancer research 1981;41(4):1257-62.
1981: Benita S Katzenellenbogen; Edward Pavlik; D W Robertson; J A Katzenellenbogen
Interaction of a high affinity anti-estrogen (alpha-[4-pyrrolidinoethoxy]phenyl-4-hydroxy-alpha'-nitrostilbene, CI628M) with uterine estrogen receptors.
The Journal of biological chemistry 1981;256(6):2908-15.
1981: M A Kneifel; Benita S Katzenellenbogen
Comparative effects of estrogen and antiestrogen on plasma renin substrate levels and hepatic estrogen receptors in the rat.
Endocrinology 1981;108(2):545-52.
1981: W De Boer; A C Notides; Benita S Katzenellenbogen; J R Hayes; J A Katzenellenbogen
The capacity of the antiestrogen CI-628 to activate the estrogen receptor in vitro.
Endocrinology 1981;108(1):206-12.
1981: J R Hayes; Ellen A Rorke; D W Robertson; Benita S Katzenellenbogen; J A Katzenellenbogen
Biological potency and uterine estrogen receptor interactions of the metabolites of the antiestrogens CI628 and U23,469.
Endocrinology 1981;108(1):164-72.
1980: Edward Pavlik; Benita S Katzenellenbogen
The stability of the uterine estrogen receptor when complexed with estrogens or antiestrogens.
Molecular pharmacology 1980;18(3):406-12.
1980: Ellen A Rorke; Benita S Katzenellenbogen
Comparative effects of estrogen and antiestrogens on enzyme activities in R3230AC rat mammary tumors and uteri of tumor-bearing animals.
Cancer research 1980;40(9):3158-62.
1980: Benita S Katzenellenbogen; N C Lan; S K Rutledge
Estrogen receptors of human endometrium: characterization of nuclear and cytoplasmic forms and comparisons with rat uterine receptors.
Journal of steroid biochemistry 1980;13(2):113-22.
1980: Benita S Katzenellenbogen
Dynamics of steroid hormone receptor action.
Annual review of physiology 1980;42():17-35.
1979: T Tatee; K E Carlson; J A Katzenellenbogen; D W Robertson; Benita S Katzenellenbogen
Antiestrogens and antiestrogen metabolites: preparation of tritium-labeled (+/-)-cis-3-[p-(1,2,3,4-tetrahydro-6-methoxy-2-phenyl-1-naphthyl)phenoxyl]-1,2-propanediol (U-23469) and characterization and synthesis of a biologically important metabolite.
Journal of medicinal chemistry 1979;22(12):1509-17.
1979: Roberta Navickis Wilkes; Benita S Katzenellenbogen; A V Nalbandov
Effects of the sex steroid hormones and vitamin D3 on calcium-binding proteins in the chick shell gland.
Biology of reproduction 1979;21(5):1153-62.
1979: T L Tsai; S Rutledge; Benita S Katzenellenbogen
Antiestrogen modulation of the growth and properties of ovarian-autonomous and ovarian-dependent mammary tumors in rats.
Cancer research 1979;39(12):5043-50.
1979: B Hammond; Benita S Katzenellenbogen; N Krauthammer; J McConnell
Estrogenic activity of the insecticide chlordecone (Kepone) and interaction with uterine estrogen receptors.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(12):6641-5.
1979: Roberta Navickis Wilkes; O K Dial; Benita S Katzenellenbogen; A V Nalbandov
Effects of gonadal hormones on calcium-binding protein in chick duodenum.
The American journal of physiology 1979;237(5):E408-17.
1979: Edward Pavlik; S Rutledge; Richard L Eckert; Benita S Katzenellenbogen
Localization of estrogen receptors in uterine cells. An appraisal of translocation.
Experimental cell research 1979;123(1):177-89.
1979: W N Schmidt; Benita S Katzenellenbogen
Androgen-uterine interactions: an assessment of androgen interaction with the testosterone- and estrogen-receptor systems and stimulation of uterine growth and progesterone-receptor synthesis.
Molecular and cellular endocrinology 1979;15(2):91-108.
1979: Benita S Katzenellenbogen; J A Katzenellenbogen; D Mordecai
Zearalenones: characterization of the estrogenic potencies and receptor interactions of a series of fungal beta-resorcylic acid lactones.
Endocrinology 1979;105(1):33-40.
1979: Benita S Katzenellenbogen; T S Tsai; T Tatee; J A Katzenellenbogen
Estrogen and antiestrogen action: studies in reproductive target tissues and tumors.
Advances in experimental medicine and biology 1979;117():111-32.
1979: Benita S Katzenellenbogen; H S Bhakoo; E R Ferguson; N C Lan; T Tatee; T S Tsai; J A Katzenellenbogen
Estrogen and antiestrogen action in reproductive tissues and tumors.
Recent progress in hormone research 1979;35():259-300.
1978: Edward Pavlik; Benita S Katzenellenbogen
Human endometrial cells in primary tissue culture: estrogen interactions and modulation of cell proliferation.
The Journal of clinical endocrinology and metabolism 1978;47(2):333-44.
1978: Benita S Katzenellenbogen; J A Katzenellenbogen; E R Ferguson; N Krauthammer
Anti-estrogen interaction with uterine estrogen receptors. Studies with a radiolabeled anti-estrogen (CI-628).
The Journal of biological chemistry 1978;253(3):697-707.
1978: Benita S Katzenellenbogen; H S Iwamoto; D F Heiman; N C Lan; J A Katzenellenbogen
Stilbestrols and stilbestrol derivatives: estrogenic potency and temporal relationships between estrogen receptor binding and uterine growth.
Molecular and cellular endocrinology 1978;10(1):103-13.
1977: H S Bhakoo; Benita S Katzenellenbogen
Progesterone modulation of estrogen-stimulated uterine biosynthetic events and estrogen receptor levels.
Molecular and cellular endocrinology 1977;8(2):121-34.
1977: H S Bhakoo; Benita S Katzenellenbogen
Progesterone antagonism of estradiol-stimulated uterine 'induced protein' synthesis.
Molecular and cellular endocrinology 1977;8(2):105-20.
1977: Benita S Katzenellenbogen; E R Ferguson; N C Lan
Fundamental differences in the action of estrogens and antiestrogens on the uterus: comparison between compounds with similar duration of action.
Endocrinology 1977;100(5):1252-9.
1977: E R Ferguson; Benita S Katzenellenbogen
A comparative study of antiestrogen action: temporal patterns of antagonism of estrogen stimulated uterine growth and effects on estrogen receptor levels.
Endocrinology 1977;100(5):1242-51.
1977: T L Tsai; Benita S Katzenellenbogen
Antagonism of development and growth of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors by the antiestrogen U 23,469 and effects on estrogen and progesterone receptors.
Cancer research 1977;37(5):1537-43.
1976: W N Schmidt; M A Sadler; Benita S Katzenellenbogen
Androgen-uterine interaction: nuclear translocation of the estrogen receptor and induction of the synthesis of the uterine-induced protein (IP) by high concentrations of androgens in vitro but not in vivo.
Endocrinology 1976;98(3):702-16.
1976: F Gannon; Benita S Katzenellenbogen; G Stancel; J Gorski
Estrogen-receptor movement to the nucleus: discussion of a cytoplasmic-exclusion hypothesis.
The symposium / The Society for Developmental Biology. Society for Developmental Biology. Symposium 1976;(34):137-49.
1976: N C Lan; Benita S Katzenellenbogen
Temporal relationships between hormone receptor binding and biological responses in the uterus: studies with short- and long-acting derivatives of estriol.
Endocrinology 1976;98(1):220-7.
1975: Benita S Katzenellenbogen; E R Ferguson
Antiestrogen action in the uterus: biological ineffectiveness of nuclear bound estradiol after antiestrogen.
Endocrinology 1975;97(1):1-12.
1975: J A Katzenellenbogen; H M Hsiung; K E Carlson; W L McGuire; R J Kraay; Benita S Katzenellenbogen
Iodohexestrols. II. Characterization of the binding and estrogenic activity of iodinated hexestrol derivatives, in vitro and in vivo.
Biochemistry 1975;14(8):1742-50.
1975: Benita S Katzenellenbogen
Synthesis and inducibility of the Uterine estrogen-induced protein, IP, during the rat estrous cycle: clues to uterine estrogen sensitivity.
Endocrinology 1975;96(2):289-97.
1975: Benita S Katzenellenbogen; J Gorski
Methods for assessing estrogen effects on new uterine protein synthesis in vitro.
Methods in enzymology 1975;36():444-55.
1974: Benita S Katzenellenbogen; N G Greger
Ontogeny of uterine responsiveness to estrogen during early development in the rat.
Molecular and cellular endocrinology 1974;2(1):31-42.
1974: Benita S Katzenellenbogen; R E Leake
Distribution of the oestrogen-induced protein and of total protein between endometrial and myometrial fractions of the immature and mature rat uterus.
The Journal of endocrinology 1974;63(3):439-49.
1974: Benita S Katzenellenbogen; L B Williams
Uterine estrogen-induced protein: physical and immunological comparison with ovalbumin.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(4):1281-5.
1973: Benita S Katzenellenbogen; J A Katzenellenbogen
Antiestrogens: studies using an in vitro estrogen-responsive uterine system.
Biochemical and biophysical research communications 1973;50(4):1152-9.
1973: T S Ruh; Benita S Katzenellenbogen; J A Katzenellenbogen; J Gorski
Estrone interaction with the rat uterus: in vitro response and nuclear uptake.
Endocrinology 1973;92(1):125-34.
1972: Benita S Katzenellenbogen; J Gorski
Estrogen action in vitro. Induction of the synthesis of a specific uterine protein.
The Journal of biological chemistry 1972;247(4):1299-305.