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S Kaufman

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TOP 3
GA Wang; P Gu; S Kaufman
Mutagenesis of the regulatory domain of phenylalanine hydroxylase.
C F Witteveen; J Giovanelli; S Kaufman
Reactivity of tetrahydrobiopterin bound to nitric-oxide synthase.
D Kowlessur; S Kaufman
Cloning and expression of recombinant human pineal tryptophan hydroxylase in Escherichia coli: purification and characterization of the cloned enzyme.

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All Publications

2001: GA Wang; P Gu; S Kaufman
Mutagenesis of the regulatory domain of phenylalanine hydroxylase.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1537-42.
1999: C F Witteveen; J Giovanelli; S Kaufman
Reactivity of tetrahydrobiopterin bound to nitric-oxide synthase.
The Journal of biological chemistry 1999;274(42):29755-62.
1999: D Kowlessur; S Kaufman
Cloning and expression of recombinant human pineal tryptophan hydroxylase in Escherichia coli: purification and characterization of the cloned enzyme.
Biochimica et biophysica acta 1999;1434(2):317-30.
1999: MA Parniak; M Davis; S Kaufman; Ellis S Kempner
Radiation target analysis indicates that phenylalanine hydroxylase in rat liver extracts is a functional monomer.
FEBS letters 1999;449(1):49-52.
1999: S Kaufman
A model of human phenylalanine metabolism in normal subjects and in phenylketonuric patients.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3160-4.
1999: XD Lei; S Kaufman
Characterization of expression of the gene for human pterin carbinolamine dehydratase/dimerization cofactor of HNF1.
DNA and cell biology 1999;18(3):243-52.
1998: GA Wang; S L Coon; S Kaufman
Alternative splicing at the 3'-cDNA of human tryptophan hydroxylase.
Journal of neurochemistry 1998;71(4):1769-72.
1998: C F Witteveen; J Giovanelli; M B Yim; R Gachhui; D J Stuehr; S Kaufman
Reactivity of the flavin semiquinone of nitric oxide synthase in the oxygenation of arginine to NG-hydroxyarginine, the first step of nitric oxide synthesis.
Biochemical and biophysical research communications 1998;250(1):36-42.
1998: L P Liang; S Kaufman
The regulation of dopamine release from striatum slices by tetrahydrobiopterin and L-arginine-derived nitric oxide.
Brain research 1998;800(2):181-6.
1998: XD Lei; S Kaufman
Human white blood cells and hair follicles are good sources of mRNA for the pterin carbinolamine dehydratase/dimerization cofactor of HNF1 for mutation detection.
Biochemical and biophysical research communications 1998;248(2):432-5.
1998: XD Lei; S Kaufman
Identification of hepatic nuclear factor 1 binding sites in the 5' flanking region of the human phenylalanine hydroxylase gene: implication of a dual function of phenylalanine hydroxylase stimulator in the phenylalanine hydroxylation system.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1500-4.
1998: S Kaufman
Genetic disorders involving recycling and formation of tetrahydrobiopterin.
Advances in pharmacology (San Diego, Calif.) 1998;42():41-3.
1997: G Johnen; S Kaufman
Studies on the enzymatic and transcriptional activity of the dimerization cofactor for hepatocyte nuclear factor 1.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13469-74.
1997: U Banik; GA Wang; P D Wagner; S Kaufman
Interaction of phosphorylated tryptophan hydroxylase with 14-3-3 proteins.
The Journal of biological chemistry 1997;272(42):26219-25.
1997: M D Davis; M A Parniak; S Kaufman; Ellis S Kempner
The role of phenylalanine in structure-function relationships of phenylalanine hydroxylase revealed by radiation target analysis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(2):491-5.
1996: D Kowlessur; Bruce A. Citron; S Kaufman
Recombinant human phenylalanine hydroxylase: novel regulatory and structural properties.
Archives of biochemistry and biophysics 1996;333(1):85-95.
1996: S Kaufman
Experiencing classical enzymology in its prime.
Protein science : a publication of the Protein Society 1996;5(8):1742-6.
1996: C F Witteveen; J Giovanelli; S Kaufman
Reduction of quinonoid dihydrobiopterin to tetrahydrobiopterin by nitric oxide synthase.
The Journal of biological chemistry 1996;271(8):4143-7.
1996: M D Davis; M A Parniak; S Kaufman; E Kempner
Structure-function relationships of phenylalanine hydroxylase revealed by radiation target analysis.
Archives of biochemistry and biophysics 1996;325(2):235-41.
1996: S Zhuo; S Fan; S Kaufman
Effects of depletion of intracellular tetrahydrobiopterin in murine erythroleukemia cells.
Experimental cell research 1996;222(1):163-70.
1995: G Johnen; D Kowlessur; Bruce A. Citron; S Kaufman
Characterization of the wild-type form of 4a-carbinolamine dehydratase and two naturally occurring mutants associated with hyperphenylalaninemia.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12384-8.
1995: D Kowlessur; X J Yang; S Kaufman
Further studies of the role of Ser-16 in the regulation of the activity of phenylalanine hydroxylase.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):4743-7.
1995: S Zhuo; S Fan; S Huang; S Kaufman
Study of the role of retinoblastoma protein in terminal differentiation of murine erythroleukemia cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4234-8.
1995: K L Campos; J Giovanelli; S Kaufman
Characteristics of the nitric oxide synthase-catalyzed conversion of arginine to N-hydroxyarginine, the first oxygenation step in the enzymic synthesis of nitric oxide.
The Journal of biological chemistry 1995;270(4):1721-8.
1995: S Kaufman
Tyrosine hydroxylase.
Advances in enzymology and related areas of molecular biology 1995;70():103-220.
1994: J P Tipper; Bruce A. Citron; P Ribeiro; S Kaufman
Cloning and expression of rabbit and human brain tryptophan hydroxylase cDNA in Escherichia coli.
Archives of biochemistry and biophysics 1994;315(2):445-53.
1994: X J Yang; S Kaufman
High-level expression and deletion mutagenesis of human tryptophan hydroxylase.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6659-63.
1994: P Ribeiro; S Kaufman
The effect of tetrahydrobiopterin on the in situ phosphorylation of tyrosine hydroxylase in rat striatal synaptosomes.
Neurochemical research 1994;19(5):541-8.
1994: Bruce A. Citron; M D Davis; S Kaufman
Electrostatic activation of rat phenylalanine hydroxylase.
Biochemical and biophysical research communications 1994;198(1):174-80.
1993: N Sakai; K Saito; S Kaufman; Melvyn P Heyes; Sheldon Milstien
Induction of pterin synthesis is not required for cytokine-stimulated tryptophan metabolism.
The Biochemical journal 1993;295 ( Pt 2)():543-7.
1993: Bruce A. Citron; S Kaufman; Sheldon Milstien; E W Naylor; Carol L Greene; M D Davis
Mutation in the 4a-carbinolamine dehydratase gene leads to mild hyperphenylalaninemia with defective cofactor metabolism.
American journal of human genetics 1993;53(3):768-74.
1993: M D Davis; S Kaufman
Products of the tyrosine-dependent oxidation of tetrahydrobiopterin by rat liver phenylalanine hydroxylase.
Archives of biochemistry and biophysics 1993;304(1):9-16.
1993: S Kaufman
The phenylalanine hydroxylating system.
Advances in enzymology and related areas of molecular biology 1993;67():77-264.
1993: S Kaufman; Bruce A. Citron; M Davis; Sheldon Milstien
The isolation and characterization of clones of 4a-hydroxytetrahydrobiopterin dehydratase.
Advances in experimental medicine and biology 1993;338():97-102.
1993: Sheldon Milstien; N Sakai; S Kaufman; K Saito; Melvyn P Heyes
Role of tetrahydrobiopterin in cytokine-stimulated metabolism of tryptophan and hydroxylation of arginine.
Advances in experimental medicine and biology 1993;338():289-94.
1993: Sheldon Milstien; S Kaufman; N Sakai
Tetrahydrobiopterin biosynthesis defects examined in cytokine-stimulated fibroblasts.
Journal of inherited metabolic disease 1993;16(6):975-81.
1993: P Ribeiro; Y Wang; Bruce A. Citron; S Kaufman
Deletion mutagenesis of rat PC12 tyrosine hydroxylase regulatory and catalytic domains.
Journal of molecular neuroscience : MN 1993;4(2):125-39.
1993: S Kaufman
New tetrahydrobiopterin-dependent systems.
Annual review of nutrition 1993;13():261-86.
1993: N Sakai; S Kaufman; S Milstein
Tetrahydrobiopterin is required for cytokine-induced nitric oxide production in a murine macrophage cell line (RAW 264).
Molecular pharmacology 1993;43(1):6-10.
1992: Bruce A. Citron; M D Davis; Sheldon Milstien; J Gutierrez; D B Mendel; G R Crabtree; S Kaufman
Identity of 4a-carbinolamine dehydratase, a component of the phenylalanine hydroxylation system, and DCoH, a transregulator of homeodomain proteins.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(24):11891-4.
1992: M D Davis; P Ribeiro; J Tipper; S Kaufman
"7-tetrahydrobiopterin," a naturally occurring analogue of tetrahydrobiopterin, is a cofactor for and a potential inhibitor of the aromatic amino acid hydroxylases.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10109-13.
1992: P Ribeiro; Y Wang; Bruce A. Citron; S Kaufman
Regulation of recombinant rat tyrosine hydroxylase by dopamine.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(20):9593-7.
1992: M D Davis; S Kaufman; Sheldon Milstien
Distribution of 4a-hydroxytetrahydropterin dehydratase in rat tissues. Comparison with the aromatic amino acid hydroxylases.
FEBS letters 1992;302(1):73-6.
1992: Bruce A. Citron; M D Davis; S Kaufman
Purification and biochemical characterization of recombinant rat liver phenylalanine hydroxylase produced in Escherichia coli.
Protein expression and purification 1992;3(2):93-100.
1992: J Tipper; S Kaufman
Phenylalanine-induced phosphorylation and activation of rat hepatic phenylalanine hydroxylase in vivo.
The Journal of biological chemistry 1992;267(2):889-96.
1992: S Kaufman
Biopterin-responsive hyperphenylalaninemia.
Journal of nutritional science and vitaminology 1992;Spec No():601-6.
1992: S Kaufman
Novel aspects of metabolism and function of tetrahydrobiopterin.
Journal of nutritional science and vitaminology 1992;Spec No():492-6.
1991: Y H Wang; Bruce A. Citron; P Ribeiro; S Kaufman
High-level expression of rat PC12 tyrosine hydroxylase cDNA in Escherichia coli: purification and characterization of the cloned enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8779-83.
1991: S Kaufman
Some metabolic relationships between biopterin and folate: implications for the "methyl trap hypothesis".
Neurochemical research 1991;16(9):1031-6.
1991: P Ribeiro; D Pigeon; S Kaufman
The hydroxylation of phenylalanine and tyrosine by tyrosine hydroxylase from cultured pheochromocytoma cells.
The Journal of biological chemistry 1991;266(24):16207-11.
1991: J Giovanelli; K L Campos; S Kaufman
Tetrahydrobiopterin, a cofactor for rat cerebellar nitric oxide synthase, does not function as a reactant in the oxygenation of arginine.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(16):7091-5.
1991: M D Davis; S Kaufman
7-Tetrahydrobiopterin is an uncoupled cofactor for rat hepatic phenylalanine hydroxylase.
FEBS letters 1991;285(1):17-20.
1991: M D Davis; S Kaufman
Studies on the partially uncoupled oxidation of tetrahydropterins by phenylalanine hydroxylase.
Neurochemical research 1991;16(7):813-9.
1991: Melvyn P Heyes; Andrew Lackner; S Kaufman; Sheldon Milstien
Cerebrospinal fluid and serum neopterin and biopterin in D-retrovirus-infected rhesus macaques (Macaca mulatta): relationship to clinical and viral status.
AIDS (London, England) 1991;5(5):555-60.
1991: H U Siegmund; S Kaufman
Hydroxylation of 4-methylphenylalanine by rat liver phenylalanine hydroxylase.
The Journal of biological chemistry 1991;266(5):2903-10.
1991: M D Davis; S Kaufman; Sheldon Milstien
Conversion of 6-substituted tetrahydropterins to 7-isomers via phenylalanine hydroxylase-generated intermediates.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(2):385-9.
1990: Sheldon Milstien; C Dorche; S Kaufman
Studies on the interaction of a thiol-dependent hydrogen peroxide scavenging enzyme and phenylalanine hydroxylase.
Archives of biochemistry and biophysics 1990;282(2):346-51.
1990: Bruce A. Citron; Sheldon Milstien; J C Gutierrez; Robert A Levine; B L Yanak; S Kaufman
Isolation and expression of rat liver sepiapterin reductase cDNA.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(16):6436-40.
1989: Sheldon Milstien; S Kaufman
Immunological studies on the participation of 6-pyruvoyl tetrahydropterin (2'-oxo) reductase, an aldose reductase, in tetrahydrobiopterin biosynthesis.
Biochemical and biophysical research communications 1989;165(2):845-50.
1989: K Tanaka; S Kaufman; Sheldon Milstien
Tetrahydrobiopterin, the cofactor for aromatic amino acid hydroxylases, is synthesized by and regulates proliferation of erythroid cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(15):5864-7.
1989: M D Davis; S Kaufman
Evidence for the formation of the 4a-carbinolamine during the tyrosine-dependent oxidation of tetrahydrobiopterin by rat liver phenylalanine hydroxylase.
The Journal of biological chemistry 1989;264(15):8585-96.
1989: Sheldon Milstien; S Kaufman
The biosynthesis of tetrahydrobiopterin in rat brain. Purification and characterization of 6-pyruvoyl tetrahydropterin (2'-oxo)reductase.
The Journal of biological chemistry 1989;264(14):8066-73.
1989: S Kaufman
An evaluation of the possible neurotoxicity of metabolites of phenylalanine.
The Journal of pediatrics 1989;114(5):895-900.
1988: M D Davis; S Kaufman
The tyrosine-dependent oxidation of tetrahydropterins by lysolecithin-activated rat liver phenylalanine hydroxylase.
The Journal of biological chemistry 1988;263(33):17312-6.
1988: M D Davis; S Kaufman; Sheldon Milstien
The auto-oxidation of tetrahydrobiopterin.
European journal of biochemistry / FEBS 1988;173(2):345-51.
1988: M A Parniak; M D Davis; S Kaufman
Effect of alkaline pH on the activity of rat liver phenylalanine hydroxylase.
The Journal of biological chemistry 1988;263(3):1223-30.
1987: T J Nelson; S Kaufman
Activation of rat caudate tyrosine hydroxylase phosphatase by tetrahydropterins.
The Journal of biological chemistry 1987;262(34):16470-5.
1987: S Kaufman
Enzymology of the phenylalanine-hydroxylating system.
Enzyme 1987;38(1-4):286-95.