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Kazunori Kawamura

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Kiichi Ishiwata; Kenji Ishii; Yuichi Kimura; Kazunori Kawamura; Keiichi Oda; Toru Sasaki; Muneyuki Sakata; Michio Senda
Successive positron emission tomography measurement of cerebral blood flow and neuroreceptors in the human brain: an 11C-SA4503 study.
Masahiro Mishina; Masashi Ohyama; Kenji Ishii; Shin Kitamura; Yuichi Kimura; Kei-ichi Oda; Kazunori Kawamura; Toru Sasaki; Shiro Kobayashi; Yasuo Katayama; Kiichi Ishiwata
Low density of sigma1 receptors in early Alzheimer's disease.
Kazunori Kawamura; Hideo Tsukada; Kazuhiro Shiba; Chieko Tsuji; Norihiro Harada; Yuichi Kimura; Kiichi Ishiwata
Synthesis and evaluation of fluorine-18-labeled SA4503 as a selective sigma1 receptor ligand for positron emission tomography.

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All Publications

2008: Kiichi Ishiwata; Kenji Ishii; Yuichi Kimura; Kazunori Kawamura; Keiichi Oda; Toru Sasaki; Muneyuki Sakata; Michio Senda
Successive positron emission tomography measurement of cerebral blood flow and neuroreceptors in the human brain: an 11C-SA4503 study.
Annals of nuclear medicine 2008;22(5):411-6.
2008: Masahiro Mishina; Masashi Ohyama; Kenji Ishii; Shin Kitamura; Yuichi Kimura; Kei-ichi Oda; Kazunori Kawamura; Toru Sasaki; Shiro Kobayashi; Yasuo Katayama; Kiichi Ishiwata
Low density of sigma1 receptors in early Alzheimer's disease.
Annals of nuclear medicine 2008;22(3):151-6.
2007: Kazunori Kawamura; Hideo Tsukada; Kazuhiro Shiba; Chieko Tsuji; Norihiro Harada; Yuichi Kimura; Kiichi Ishiwata
Synthesis and evaluation of fluorine-18-labeled SA4503 as a selective sigma1 receptor ligand for positron emission tomography.
Nuclear medicine and biology 2007;34(5):571-7.
2007: Kiichi Ishiwata; Kazunori Kawamura; Kazuhiko Yanai; N Harry Hendrikse
In vivo evaluation of P-glycoprotein modulation of 8 PET radioligands used clinically.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(1):81-7.
2006: Kiichi Ishiwata; Keiichi Oda; Muneyuki Sakata; Yuichi Kimura; Kazunori Kawamura; Keiichi Oda; Toru Sasaki; Mika Naganawa; Kunihiro Chihara; Yoshiro Okubo; Kenji Ishii
A feasibility study of [11C]SA4503-PET for evaluating sigmal receptor occupancy by neuroleptics: the binding of haloperidol to sigma1 and dopamine D2-like receptors.
Annals of nuclear medicine 2006;20(8):569-73.
2006: Kazuo Kubota; Shozo Furumoto; Ren Iwata; Hiroshi Fukuda; Kazunori Kawamura; Kiichi Ishiwata
Comparison of 18F-fluoromethylcholine and 2-deoxy-D-glucose in the distribution of tumor and inflammation.
Annals of nuclear medicine 2006;20(8):527-33.
2006: Kiichi Ishiwata; Han-yu Liu; Kenichi Teramoto; Kazunori Kawamura; Keiichi Oda; Shigeki Arii
Tumor viability evaluation by positron emission tomography with [18F]FDG in the liver metastasis rat model.
Annals of nuclear medicine 2006;20(7):463-9.
2006: Kazunori Kawamura; Kazuhiro Shiba; Hideo Tsukada; Shingo Nishiyama; Hirofumi Mori; Kiichi Ishiwata
Synthesis and evaluation of vesamicol analog (-)-O-[11C]methylvesamicol as a PET ligand for vesicular acetylcholine transporter.
Annals of nuclear medicine 2006;20(6):417-24.
2006: Kiichi Ishiwata; Kazunori Kawamura; Kazuyoshi Yajima; Hirofumi Mori; Kazuhiro Shiba
Evaluation of (+)-p-[11C]methylvesamicol for mapping sigma1 receptors: a comparison with [11C]SA4503.
Nuclear medicine and biology 2006;33(4):543-8.
2005: Kazunori Kawamura; Kazuo Kubota; Tadayuki Kobayashi; Philip H Elsinga; Mayumi Ono; Minoru Maeda; Kiichi Ishiwata
Evaluation of [11C]SA5845 and [11C]SA4503 for imaging of sigma receptors in tumors by animal PET.
Annals of nuclear medicine 2005;19(8):701-9.
2005: Kiichi Ishiwata; Hideo Tsukada; Kazuo Kubota; Tadashi Nariai; Norihiro Harada; Kazunori Kawamura; Yuichi Kimura; Keiichi Oda; Ren Iwata; Kenji Ishii
Preclinical and clinical evaluation of O-[11C]methyl-L-tyrosine for tumor imaging by positron emission tomography.
Nuclear medicine and biology 2005;32(3):253-62.
2004: Yuichi Kimura; Kenji Ishii; Nobuyoshi Fukumitsu; Keiichi Oda; Toru Sasaki; Kazunori Kawamura; Kiichi Ishiwata
Quantitative analysis of adenosine A1 receptors in human brain using positron emission tomography and [1-methyl-11C]8-dicyclopropylmethyl-1-methyl-3-propylxanthine.
Nuclear medicine and biology 2004;31(8):975-81.
2004: Kiichi Ishiwata; Masaki Mizuno; Yuichi Kimura; Kazunori Kawamura; Keiichi Oda; Toru Sasaki; Yoshio Nakamura; Isao Muraoka; Kenji Ishii
Potential of [11C]TMSX for the evaluation of adenosine A2A receptors in the skeletal muscle by positron emission tomography.
Nuclear medicine and biology 2004;31(7):949-56.
2004: Wei-Fang Wang; Kiichi Ishiwata; Motohiro Kiyosawa; Kazunori Kawamura; Keiichi Oda; Kiyoshi Matsuno; Tadayuki Kobayashi; Manabu Mochizuki
Investigation of the use of positron emission tomography for neuroreceptor imaging in rabbit eyes.
Ophthalmic research 2004;36(5):255-63.
2004: Kiichi Ishiwata; Kazunori Kawamura; Wei-Fang Wang; Hideo Tsukada; Norihiro Harada; Hideki Mochizuki; Yuichi Kimura; Kenji Ishii; Ren Iwata; Kazuhiko Yanai
Evaluation of in vivo selective binding of [11C]doxepin to histamine H1 receptors in five animal species.
Nuclear medicine and biology 2004;31(4):493-502.
2004: Kazunori Kawamura; Kiichi Ishiwata
Improved synthesis of [11C]SA4503, [11C]MPDX and [11C]TMSX by use of [11C]methyl triflate.
Annals of nuclear medicine 2004;18(2):165-8.
2004: Kiichi Ishiwata; Kazunori Kawamura; Wei-Fang Wang; Shozo Furumoto; Kazuo Kubota; Claudio Pascali; Anna Bogni; Ren Iwata
Evaluation of O-[11C]methyl-L-tyrosine and O-[18F]fluoromethyl-L-tyrosine as tumor imaging tracers by PET.
Nuclear medicine and biology 2004;31(2):191-8.
2003: Kiichi Ishiwata; Kazunori Kawamura; Yuichi Kimura; Keiichi Oda; Kenji Ishii
Potential of an adenosine A2A receptor antagonist [11C]TMSX for myocardial imaging by positron emission tomography: a first human study.
Annals of nuclear medicine 2003;17(6):457-62.
2003: Kazunori Kawamura; Yuichi Kimura; Hideo Tsukada; Tadayuki Kobayashi; Shingo Nishiyama; Takeharu Kakiuchi; Hiroyuki Ohba; Norihiro Harada; Kiyoshi Matsuno; Kenji Ishii; Kiichi Ishiwata
An increase of sigma receptors in the aged monkey brain.
Neurobiology of aging 2003;24(5):745-52.
2003: Kazunori Kawamura; Keiichi Oda; Kiichi Ishiwata
Age-related changes of the [11C]CFT binding to the striatal dopamine transporters in the Fischer 344 rats: a PET study.
Annals of nuclear medicine 2003;17(3):249-53.
2003: Kiichi Ishiwata; Wei-Fang Wang; Yuichi Kimura; Kazunori Kawamura; Kenji Ishii
Preclinical studies on [11C]TMSX for mapping adenosine A2A receptors by positron emission tomography.
Annals of nuclear medicine 2003;17(3):205-11.
2003: Kiichi Ishiwata; Kazunori Kawamura; Tadayuki Kobayashi; Kiyoshi Matsuno
Sigma1 and dopamine D2 receptor occupancy in the mouse brain after a single administration of haloperidol and two dopamine D2-like receptor ligands.
Nuclear medicine and biology 2003;30(4):429-34.
2003: Kazunori Kawamura; Tadayuki Kobayashi; Kiyoshi Matsuno; Kiichi Ishiwata
Different brain kinetics of two sigma 1 receptor ligands, [3H](+)-pentazocine and [11C]SA4503, by P-glycoprotein modulation.
Synapse (New York, N.Y.) 2003;48(2):80-6.
2003: Kazunori Kawamura; Philip H Elsinga; Tadayuki Kobayashi; Shin-ichi Ishii; Wei-Fang Wang; Kiyoshi Matsuno; Willem Vaalburg; Kiichi Ishiwata
Synthesis and evaluation of 11C- and 18F-labeled 1-[2-(4-alkoxy-3-methoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazines as sigma receptor ligands for positron emission tomography studies.
Nuclear medicine and biology 2003;30(3):273-84.
2003: Kiichi Ishiwata; Tadayuki Kobayashi; Kazunori Kawamura; Kiyoshi Matsuno
Age-related changes of the binding of [3h]SA4503 to sigma1 receptors in the rat brain.
Annals of nuclear medicine 2003;17(1):73-7.
2003: Kiichi Ishiwata; Yasuhiro Koyanagi; Kenji Abe; Kazunori Kawamura; Kyoji Taguchi; Toshiaki Saitoh; Jun Toda; Takehiro Sano
No reduction of dopamine transporter binding sites in mice following treatment with the TIQ analogue 1-benzyl-1,2,3,4-tetrahydroisoquinoline.
Brain research 2003;960(1-2):282-5.
2002: Wei-Fang Wang; Kiichi Ishiwata; Motohiro Kiyosawa; Kazunori Kawamura; Keiichi Oda; Tadayuki Kobayashi; Kiyoshi Matsuno; Manabu Mochizuki
Visualization of sigma1 receptors in eyes by ex vivo autoradiography and in vivo positron emission tomography.
Experimental eye research 2002;75(6):723-30.
2002: Kiichi Ishiwata; Tadashi Nariai; Yuichi Kimura; Keiichi Oda; Kazunori Kawamura; Kenji Ishii; Michio Senda; Shinichi Wakabayashi; Junichi Shimada
Preclinical studies on [11C]MPDX for mapping adenosine A1 receptors by positron emission tomography.
Annals of nuclear medicine 2002;16(6):377-82.
2002: Toru Sasaki; Kazunori Kawamura; Yasukazu Tanaka; Susumu Ando; Michio Senda
Assessment of choline uptake for the synthesis and release of acetylcholine in brain slices by a dynamic autoradiographic technique using [11C]choline.
Brain research. Brain research protocols 2002;10(1):1-11.
2001: Kiichi Ishiwata; Yasuhiro Koyanagi; K Abe; Kazunori Kawamura; Kyoji Taguchi; Toshiaki Saitoh; Jun Toda; Michio Senda; Takehiro Sano
Evaluation of neurotoxicity of TIQ and MPTP and of parkinsonism-preventing effect of 1-MeTIQ by in vivo measurement of pre-synaptic dopamine transporters and post-synaptic dopamine D(2) receptors in the mouse striatum.
Journal of neurochemistry 2001;79(4):868-76.
2001: Kiichi Ishiwata; Tadayuki Kobayashi; Kazunori Kawamura; Kiyoshi Matsuno; Michio Senda
[11C]Raclopride binding was reduced in vivo by sigma(1) receptor ligand SA4503 in the mouse brain, while [11C]SA4503 binding was not by raclopride.
Nuclear medicine and biology 2001;28(7):787-92.
2001: Kiichi Ishiwata; Hideo Tsukada; Kazunori Kawamura; Yuichi Kimura; Shingo Nishiyama; Tadayuki Kobayashi; Kiyoshi Matsuno; Michio Senda
Mapping of CNS sigma(1) receptors in the conscious monkey: preliminary PET study with [(11)C]SA4503.
Synapse (New York, N.Y.) 2001;40(3):235-7.
2000: Kazunori Kawamura; Kiichi Ishiwata; Yuhei Shimada; Yuichi Kimura; Tadayuki Kobayashi; Kiyoshi Matsuno; Y Homma; Michio Senda
Preclinical evaluation of [11C]SA4503: radiation dosimetry, in vivo selectivity and PET imaging of sigma1 receptors in the cat brain.
Annals of nuclear medicine 2000;14(4):285-92.
2000: Kazunori Kawamura; Kiichi Ishiwata; H Tajima; Shin-ichi Ishii; Kiyoshi Matsuno; Y Homma; Michio Senda
In vivo evaluation of [(11)C]SA4503 as a PET ligand for mapping CNS sigma(1) receptors.
Nuclear medicine and biology 2000;27(3):255-61.
1999: Kazunori Kawamura; Kiichi Ishiwata; H Tajima; Shin-ichi Ishii; Yuhei Shimada; Kiyoshi Matsuno; Y Homma; Michio Senda
Synthesis and in vivo evaluation of [11C]SA6298 as a PET sigma1 receptor ligand.
Nuclear medicine and biology 1999;26(8):915-22.