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Takako Kawasaki

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Chromosomes, Human, Pair 18

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Katsuhiko Nosho; Takako Kawasaki; A T Chan; Mutsuko Ohnishi; Yuko Suemoto; Gregory J Kirkner; Charlie S Fuchs; Shuji Ogino
Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype.
Shuji Ogino; Takako Kawasaki; Katsuhiko Nosho; Mutsuko Ohnishi; Yuko Suemoto; Gregory J Kirkner; Charlie S Fuchs
LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Katsuhiko Nosho; Takako Kawasaki; Mutsuko Ohnishi; Yuko Suemoto; Gregory J Kirkner; Dimity Zepf; Liying Yan; Janina A Longtine; Charlie S Fuchs; Shuji Ogino
PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.

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2008: Katsuhiko Nosho; Takako Kawasaki; A T Chan; Mutsuko Ohnishi; Yuko Suemoto; Gregory J Kirkner; Charlie S Fuchs; Shuji Ogino
Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype.
Histopathology 2008;53(5):588-98.
2008: Shuji Ogino; Takako Kawasaki; Katsuhiko Nosho; Mutsuko Ohnishi; Yuko Suemoto; Gregory J Kirkner; Charlie S Fuchs
LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
International journal of cancer. Journal international du cancer 2008;122(12):2767-73.
2008: Katsuhiko Nosho; Takako Kawasaki; Mutsuko Ohnishi; Yuko Suemoto; Gregory J Kirkner; Dimity Zepf; Liying Yan; Janina A Longtine; Charlie S Fuchs; Shuji Ogino
PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.
Neoplasia (New York, N.Y.) 2008;10(6):534-41.
2008: Takako Kawasaki; Mutsuko Ohnishi; Katsuhiko Nosho; Yuko Suemoto; Gregory J Kirkner; Jeffrey A Meyerhardt; Charlie S Fuchs; Shuji Ogino
CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008;21(3):245-55.
2008: Takako Kawasaki; Mutsuko Ohnishi; Yuko Suemoto; Gregory J Kirkner; Zhiqian Liu; Hiroyuki Yamamoto; Massimo Loda; Charlie S Fuchs; Shuji Ogino
WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008;21(2):150-8.
2008: Takako Kawasaki; Katsuhiko Nosho; Mutsuko Ohnishi; Yuko Suemoto; Jonathan N Glickman; Andrew T Chan; Gregory J Kirkner; Mari Mino-Kenudson; Charlie S Fuchs; Shuji Ogino
Cyclooxygenase-2 overexpression is common in serrated and non-serrated colorectal adenoma, but uncommon in hyperplastic polyp and sessile serrated polyp/adenoma.
BMC cancer 2008;8():33.
2007: Takako Kawasaki; Katsuhiko Nosho; Mutsuko Ohnishi; Yuko Suemoto; Gregory J Kirkner; Charlie S Fuchs; Shuji Ogino
IGFBP3 promoter methylation in colorectal cancer: relationship with microsatellite instability, CpG island methylator phenotype, and p53.
Neoplasia (New York, N.Y.) 2007;9(12):1091-8.
2007: Shuji Ogino; Takako Kawasaki; Gregory J Kirkner; Yuko Suemoto; Jeffrey A Meyerhardt; Charlie S Fuchs
Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.
Gut 2007;56(11):1564-71.
2007: Shuji Ogino; Aditi Hazra; Gregory J Tranah; Gregory J Kirkner; Takako Kawasaki; Katsuhiko Nosho; Mutsuko Ohnishi; Yuko Suemoto; Jeffrey A Meyerhardt; David J Hunter; Charlie S Fuchs
MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.
Carcinogenesis 2007;28(9):1985-90.
2007: Takako Kawasaki; Katsuhiko Nosho; Mutsuko Ohnishi; Yuko Suemoto; Gregory J Kirkner; Reiko Dehari; Jeffrey A Meyerhardt; Charlie S Fuchs; Shuji Ogino
Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer.
Neoplasia (New York, N.Y.) 2007;9(7):569-77.
2007: Shuji Ogino; Takako Kawasaki; Gregory J Kirkner; Peter Kraft; Massimo Loda; Charlie S Fuchs
Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample.
The Journal of molecular diagnostics : JMD 2007;9(3):305-14.
2007: Shuji Ogino; Takako Kawasaki; Akiyo Ogawa; Gregory J Kirkner; Massimo Loda; Charlie S Fuchs
Fatty acid synthase overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Human pathology 2007;38(6):842-9.
2007: Shuji Ogino; Jeffrey A Meyerhardt; Takako Kawasaki; jeffrey clark; David P Ryan; Matthew H Kulke; Peter C Enzinger; Brian M Wolpin; Massimo Loda; Charlie S Fuchs
CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma.
Virchows Archiv : an international journal of pathology 2007;450(5):529-37.
2007: Shuji Ogino; Takako Kawasaki; Akiyo Ogawa; Gregory J Kirkner; Massimo Loda; Charlie S Fuchs
TGFBR2 mutation is correlated with CpG island methylator phenotype in microsatellite instability-high colorectal cancer.
Human pathology 2007;38(4):614-20.
2007: Shuji Ogino; Takako Kawasaki; Akiyo Ogawa; Gregory J Kirkner; Massimo Loda; Charlie S Fuchs
Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype.
Human pathology 2007;38(4):585-92.
2007: Shuji Ogino; Takako Kawasaki; Gregory J Kirkner; Mutsuko Ohnishi; Charlie S Fuchs
18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high.
BMC cancer 2007;7():72.
2007: Shuji Ogino; Takako Kawasaki; Gregory J Kirkner; Taiki Yamaji; Massimo Loda; Charlie S Fuchs
Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(1):15-22.
2006: Shuji Ogino; Takako Kawasaki; Gregory J Kirkner; Massimo Loda; Charlie S Fuchs
CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations.
The Journal of molecular diagnostics : JMD 2006;8(5):582-8.
2006: Shuji Ogino; Takako Kawasaki; Gregory J Kirkner; Akiyo Ogawa; I Dorfman; Massimo Loda; Charlie S Fuchs
Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer.
The Journal of pathology 2006;210(2):147-54.
2006: Shuji Ogino; Robert D Odze; Takako Kawasaki; Mohan Brahmandam; Gregory J Kirkner; Peter W Laird; Massimo Loda; Charlie S Fuchs
Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma.
The American journal of surgical pathology 2006;30(9):1175-83.
2006: Shuji Ogino; Mohan Brahmandam; Takako Kawasaki; Gregory J Kirkner; Massimo Loda; Charlie S Fuchs
Epigenetic profiling of synchronous colorectal neoplasias by quantitative DNA methylation analysis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006;19(8):1083-90.
2006: Shuji Ogino; Mami Cantor; Takako Kawasaki; Mohan Brahmandam; Gregory J Kirkner; Daniel J Weisenberger; Mihaela Campan; Peter W Laird; Massimo Loda; Charlie S Fuchs
CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies.
Gut 2006;55(7):1000-6.
2006: Shuji Ogino; Mohan Brahmandam; Takako Kawasaki; Gregory J Kirkner; Massimo Loda; Charlie S Fuchs
Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Neoplasia (New York, N.Y.) 2006;8(6):458-64.
2006: Shuji Ogino; Takako Kawasaki; Mohan Brahmandam; Mami Cantor; Gregory J Kirkner; Donna Spiegelman; Michael G Makrigiorgos; Daniel J Weisenberger; Peter W Laird; Massimo Loda; Charlie S Fuchs
Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis.
The Journal of molecular diagnostics : JMD 2006;8(2):209-17.
2006: Shuji Ogino; Mohan Brahmandam; Mami Cantor; Chungdak Namgyal; Takako Kawasaki; Gregory J Kirkner; Jeffrey A Meyerhardt; Massimo Loda; Charlie S Fuchs
Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006;19(1):59-68.
2005: Shuji Ogino; Jeffrey A Meyerhardt; Mami Cantor; Mohan Brahmandam; jeffrey clark; Chungdak Namgyal; Takako Kawasaki; Kate Kinsella; Ann Michelini; Peter C Enzinger; Matthew H Kulke; David P Ryan; Massimo Loda; Charlie S Fuchs
Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(18):6650-6.
2005: Shuji Ogino; Takako Kawasaki; Mohan Brahmandam; Liying Yan; Mami Cantor; Chungdak Namgyal; Mari Mino-Kenudson; Gregory Y Lauwers; Massimo Loda; Charlie S Fuchs
Sensitive sequencing method for KRAS mutation detection by Pyrosequencing.
The Journal of molecular diagnostics : JMD 2005;7(3):413-21.