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Makoto Kawatani

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Chemicals & Drugs

Disorders

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Toshihiko Nogawa; Makoto Kawatani; Hiroyuki Koshino; Yasuyo Sekiyama; Takeshi Shimizu; Hiroshi Takagi; Shunji Takahashi; Masakazu Uramoto; Hiroyuki Osada
Creation of novel reveromycin derivatives by alcohol-added fermentation.
Yushi Futamura; Makoto Kawatani; Sayaka Kazami; Makoto Muroi; Takeshi Shimizu; Kenichi Tanaka; Koji Tomita; Nobumoto Watanabe; Hiroyuki Osada
Morphobase, an encyclopedic cell morphology database, and its use for drug target identification.
Makoto Kawatani; Hiroyuki Osada
[Cytoskeletal system].

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2013: Toshihiko Nogawa; Makoto Kawatani; Hiroyuki Koshino; Yasuyo Sekiyama; Takeshi Shimizu; Hiroshi Takagi; Shunji Takahashi; Masakazu Uramoto; Hiroyuki Osada
Creation of novel reveromycin derivatives by alcohol-added fermentation.
The Journal of antibiotics 2013;66(4):247-50.
2012: Yushi Futamura; Makoto Kawatani; Sayaka Kazami; Makoto Muroi; Takeshi Shimizu; Kenichi Tanaka; Koji Tomita; Nobumoto Watanabe; Hiroyuki Osada
Morphobase, an encyclopedic cell morphology database, and its use for drug target identification.
Chemistry & biology 2012;19(12):1620-30.
2012: Makoto Kawatani; Hiroyuki Osada
[Cytoskeletal system].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 8():130-4.
2012: Maola M G Khan; Akiko Masuda; Makoto Muroi; Naoshi Dohmae; Makoto Kawatani; Siro Simizu; Takehiro Suzuki; Hiroyuki Osada
Protein disulfide isomerase-mediated disulfide bonds regulate the gelatinolytic activity and secretion of matrix metalloproteinase-9.
Experimental cell research 2012;318(8):904-14.
2011: Makoto Kawatani; Shinya Kimura; Taira Maekawa; Makoto Muroi; Hiroshi Takayama; Hiroyuki Osada
Identification of a small-molecule inhibitor of DNA topoisomerase II by proteomic profiling.
Chemistry & biology 2011;18(6):743-51.
2011: Naoki Kato; Makoto Kawatani; Katsuhiko Kitamoto; Yasuji Koyama; Yasuyo Seshime; Yasutomo Shinohara; Shunji Takahashi; Tadashi Takahashi; Masafumi Tokuoka; Masakazu Uramoto; Isao Fujii; Hiroyuki Osada
Genetic safeguard against mycotoxin cyclopiazonic acid production in Aspergillus oryzae.
Chembiochem : a European journal of chemical biology 2011;12(9):1376-82.
2011: Maola M G Khan; Siro Simizu; Ngit Shin Lai; Makoto Kawatani; Takeshi Shimizu; Hiroyuki Osada
Discovery of a small molecule PDI inhibitor that inhibits reduction of HIV-1 envelope glycoprotein gp120.
ACS chemical biology 2011;6(3):245-51.
2011: Maola M G Khan; Makoto Kawatani; Siro Simizu; Hiroyuki Osada
The potential of protein disulfide isomerase as a therapeutic drug target.
Oncology research 2011;19(10-11):445-53.
2010: Makoto Muroi; Sayaka Kazami; Kazue Noda; Hisae Kondo; Hiroshi Takayama; Makoto Kawatani; Takeo Usui; Hiroyuki Osada
Application of proteomic profiling based on 2D-DIGE for classification of compounds according to the mechanism of action.
Chemistry & biology 2010;17(5):460-70.
2006: Naoki Kanoh; Aya Asami; Makoto Kawatani; Kaori Honda; Saori Kumashiro; Hiroshi Takayama; Siro Simizu; Tomoyuki Amemiya; Yasumitsu Kondoh; Satoru Hatakeyama; Keiko Tsuganezawa; Rei Utata; Akiko Tanaka; Shigeyuki Yokoyama; Hideo Tashiro; Hiroyuki Osada
Photo-cross-linked small-molecule microarrays as chemical genomic tools for dissecting protein-ligand interactions.
Chemistry, an Asian journal 2006;1(6):789-97.
2006: Je-Tae Woo; Makoto Kawatani; Masanori Kato; Toshimasa Shinki; Takayuki Yonezawa; Naoki Kanoh; Hiroshi Nakagawa; Masamichi Takami; Kun-Hyung Lee; Paula H Stern; Kazuo Nagai; Hiroyuki Osada
Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(12):4729-34.
2003: Makoto Kawatani; Masaya Imoto
Deletion of the BH1 domain of Bcl-2 accelerates apoptosis by acting in a dominant negative fashion.
The Journal of biological chemistry 2003;278(22):19732-42.
2003: Makoto Kawatani; Madoka Uchi; Siro Simizu; Hiroyuki Osada; Masaya Imoto
Transmembrane domain of Bcl-2 is required for inhibition of ceramide synthesis, but not cytochrome c release in the pathway of inostamycin-induced apoptosis.
Experimental cell research 2003;286(1):57-66.
2001: Yasushi Takemoto; Koichi Nakae; Makoto Kawatani; Yoshikazu Takahashi; Hiroshi Naganawa; Masaya Imoto
Migrastatin, a novel 14-membered ring macrolide, inhibits anchorage-independent growth of human small cell lung carcinoma Ms-1 cells.
The Journal of antibiotics 2001;54(12):1104-7.
2000: Makoto Kawatani; Siro Simizu; Hiroyuki Osada; M Takada; N Arber; Masaya Imoto
Involvement of protein kinase C-regulated ceramide generation in inostamycin-induced apoptosis.
Experimental cell research 2000;259(2):389-97.
2000: Y Matsumoto; Makoto Kawatani; Siro Simizu; T Tanaka; M Takada; Masaya Imoto
Bcl-2-independent induction of apoptosis by neuropeptide receptor antagonist in human small cell lung carcinoma cells.
Anticancer research 2000;20(5A):3123-9.