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Y Kawazoe

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Disorders

Leukemia L1210

Concepts & Ideas

Structure-Activity Relationship

Anatomy

Physiology

Cell Survival

Procedures

Mutagenicity Tests

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Co-Publications
Name
23
Kohda, Kohfuku
21
Sakagami, Hiroshi
13
Shimizu, N
8
Saeki, Ken-ichi
6
Sekiguchi, Mutsuo
5
Hakura, Atsushi
5
Kaiya, Toyo
4
Kohara, Arihiro
4
Noda, Yasuhiro
4
Tanuma, Sei-ichi
3
Ota, Yuko
2
Suzuki, Takayoshi
2
Sakumi, Kunihiko
2
Fukuchi, Kunihiko
1
Furuno, Tadahide

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Publications

TOP 3
Saeki K; Kadoi M; Kawazoe Y; Igarashi M; Shimada H
Clastogenicity of quinoline derivatives tested by micronucleus induction in vivo in the hepatocytes of partially hepatectomized mice.
Saeki K; Murakami R; Kohara A; Shimizu N; Kawai H; Kawazoe Y; Hakura A
Substituent effect of a fluorine atom on the mutagenicity of nitroquinolines.
Kato T; Saeki K; Kawazoe Y; Hakura A
Effects of oligofluorine substitution on the mutagenicity of quinoline: a study with twelve fluoroquinoline derivatives.

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All Publications

2000: Saeki K; Kadoi M; Kawazoe Y; Igarashi M; Shimada H
Clastogenicity of quinoline derivatives tested by micronucleus induction in vivo in the hepatocytes of partially hepatectomized mice.
Biological & pharmaceutical bulletin 2000;23(2):219-21.
1999: Saeki K; Murakami R; Kohara A; Shimizu N; Kawai H; Kawazoe Y; Hakura A
Substituent effect of a fluorine atom on the mutagenicity of nitroquinolines.
Mutation research 1999;441(2):205-13.
1999: Kato T; Saeki K; Kawazoe Y; Hakura A
Effects of oligofluorine substitution on the mutagenicity of quinoline: a study with twelve fluoroquinoline derivatives.
Mutation research 1999;439(2):149-57.
1998: Kohara A; Shimizu N; Kawazoe Y
Cytotoxic factor induced in murine serum after intravenous administration of a dehydrogenation polymer of p-coumaric acid (a synthetic lignin).
Biological & pharmaceutical bulletin 1998;21(10):1098-101.
1998: Miyata Y; Saeki K; Kawazoe Y; Hayashi M; Sofuni T; Suzuki T
Antimutagenic structural modification of quinoline assessed by an in vivo mutagenesis assay using lacZ-transgenic mice.
Mutation research 1998;414(1-3):165-9.
1998: Noda Y; Hayatsu H; Kawazoe Y
Effects of treatment with nimustine (ACNU), a bifunctional alkylating anticancer agent, on cultured resting L1210 cells.
Biological & pharmaceutical bulletin 1998;21(4):414-7.
1997: Noda Y; Kawazoe Y; Hakura A
Cytotoxicity of naphthoquinones toward cultured resting murine leukemia L1210 cells in the presence of glutathione, diethyl maleate, or iodoacetamide.
Biological & pharmaceutical bulletin 1997;20(12):1250-6.
1997: Noda Y; Kaiya T; Kohda K; Kawazoe Y
Enhanced cytotoxicity of some triterpenes toward leukemia L1210 cells cultured in low pH media: possibility of a new mode of cell killing.
Chemical & pharmaceutical bulletin 1997;45(10):1665-70.
1997: Shimizu N; Kohara A; Kawazoe Y
Characterization of a cytotoxic factor induced in murine serum after the intravenous administration of dehydrogenation polymers of phenylpropenoids (a class of synthetic lignins).
Biological & pharmaceutical bulletin 1997;20(8):838-42.
1997: Shimizu N; Kawazoe Y; Furuno T; Nakanishi M
Internalization of non-permeant materials into cultured mammalian cells by vortex-stirring in the presence of a high molecular weight polyacrylic acid: direct evidence of internalization and its dependence on the cell lines.
Biological & pharmaceutical bulletin 1997;20(7):727-31.
1997: Saeki K; Kawai H; Kawazoe Y; Hakura A
Dual stimulatory and inhibitory effects of fluorine-substitution on mutagenicity: an extension of the enamine epoxide theory for activation of the quinoline nucleus.
Biological & pharmaceutical bulletin 1997;20(6):646-50.
1997: Shimizu N; Wu W; Kohara A; Kohda K; Suzuki T; Kawazoe Y
Enhanced cytotoxicity of alkyl viologens and N,N'-diamino analogs toward cultured murine leukemia L1210 cells under vortex-stirring with a high molecular weight polyacrylic acid.
Biological & pharmaceutical bulletin 1997;20(2):168-70.
1997: Saeki K; Kadoi M; Kawazoe Y; Futakuchi M; Tiwawech D; Shirai T
Modification of the carcinogenic potency of quinoline, a hepatocarcinogen, by fluorine atom substitution: evaluation of carcinogenicity by a medium-term assay.
Biological & pharmaceutical bulletin 1997;20(1):40-3.
1996: Noda Y; Shimizu N; Kawazoe Y
A new method for permeabilization of the plasma membrane of cultured mammalian cells. VII. Permeabilization of growing and resting cells by vortex-stirring with high molecular weight polyacrylic acid.
Biological & pharmaceutical bulletin 1996;19(12):1565-9.
1996: Shimizu N; Kawazoe Y
Delicate and crucial pH dependence in permeabilization of cultured mammalian cells by vortex-stirring with a high molecular weight polyacrylic acid.
Biological & pharmaceutical bulletin 1996;19(11):1533-5.
1996: Shimizu N; Kawazoe Y
A new method for permeabilization of the plasma membrane of cultured mammalian cells. V. A standard procedure recommended for permeabilization by vortex-stirring with high molecular weight polyacrylic acid.
Biological & pharmaceutical bulletin 1996;19(10):1279-84.
1996: Shimizu N; Nakamura M; Azuchi M; Okada M; Kawazoe Y
A new method for permeabilization of the plasma membrane of cultured mammalian cells. IV. Structural requirement for high molecular weight polymers for potentiation of bleomycin cytotoxicity toward mammalian cells under conditions of vortex-stirring.
Biological & pharmaceutical bulletin 1996;19(9):1126-9.
1996: Shimizu N; Kawazoe Y
A new method for permeabilization of the plasma membrane of cultured mammalian cells. III. Internalization of fluorescent dextrans into cultured mammalian cells by vortex-stirring in the presence of high molecular weight polyacrylic acid.
Biological & pharmaceutical bulletin 1996;19(8):1023-5.
1996: Kasamatsu T; Kohda K; Kawazoe Y
Comparison of chemically induced DNA breakage in cellular and subcellular systems using the comet assay.
Mutation research 1996;369(1-2):1-6.
1996: Shimizu N; Kawazoe Y
A new method for permeabilization of the plasma membrane of cultured mammalian cells. II. Mechanism for potentiation of bleomycin cytotoxicity by vortex-stirring with high molecular weight polyacrylic acid.
Biological & pharmaceutical bulletin 1996;19(6):805-8.
1996: Kasamatsu T; Kohda K; Kawazoe Y
Synergetic cytotoxicity of bleomycin and polyhydric alcohols: DNA strand breakage evaluated by "comet assay".
Biological & pharmaceutical bulletin 1996;19(4):632-5.
1996: Saeki K; Takahashi K; Kawazoe Y
Potent mutagenic potential of 4-methylquinoline: metabolic and mechanistic considerations.
Biological & pharmaceutical bulletin 1996;19(4):541-6.
1996: Shimizu N; Kawazoe Y
A new method for permeabilization of cultured cells without cell damage.
Biological & pharmaceutical bulletin 1996;19(3):484-6.
1995: Kasamatsu T; Kohda K; Kawazoe Y
Cytotoxicity of antitumor agents toward cultured murine leukemia L1210 cells under a serum-deprived apoptotic condition.
Anticancer research 1995;15(6B):2597-600.
1995: Sakagami H; Kuribayashi N; Iida M; Sakagami T; Takeda M; Fukuchi K; Gomi K; Ohata H; Momose K; Kawazoe Y
Induction of DNA fragmentation by tannin- and lignin-related substances.
Anticancer research 1995;15(5B):2121-8.
1995: Sakagami H; Sakagami T; Yoshida H; Omata T; Shiota F; Takahashi H; Kawazoe Y; Takeda M
Hypochlorite scavenging activity of polyphenols.
Anticancer research 1995;15(3):917-21.
1993: Sakagami H; Utsumi A; Fujinaga S; Takeda M; Naoe T; Kawazoe Y
Stimulation of iodination and cytokine production by dehydrogenation polymers of phenylpropenoids.
Anticancer research 1993;13(4):1001-5.
1993: Shimizu N; Naoe T; Kawazoe Y; Sakagami H; Nakashima H; Murakami T; Yamamoto N
Lignified materials as medicinal resources. VI. Anti-HIV activity of dehydrogenation polymer of p-coumaric acid, a synthetic lignin, in a quasi-in-vivo assay system as an intermediary step to clinical trials.
Biological & pharmaceutical bulletin 1993;16(4):434-6.
1993: Saeki K; Takahashi K; Kawazoe Y
Metabolism of mutagenicity-deprived 3-fluoroquinoline: comparison with mutagenic quinoline.
Biological & pharmaceutical bulletin 1993;16(3):232-4.
1992: Sakagami H; Kohno S; Takeda M; Nakamura K; Nomoto K; Ueno I; Kanegasaki S; Naoe T; Kawazoe Y
O2- scavenging activity of lignins, tannins and PSK.
Anticancer research 1992;12(6B):1995-2000.
1992: Sakagami H; Takeda M; Kawazoe Y; Nagata K; Ishihama A; Ueda M; Yamazaki S
Anti-influenza virus activity of a lignin fraction from cone of Pinus parviflora Sieb. et Zucc.
In vivo (Athens, Greece) 1992;6(5):491-5.
1992: Takahashi K; Suzuki M; Sekiguchi M; Kawazoe Y
Effect of metal ions on transcription of the ada gene which encodes O6-methylguanine-DNA methyltransferase of Escherichia coli.
Chemical & pharmaceutical bulletin 1992;40(9):2483-6.
1992: Sakagami H; Kuroiwa Y; Takeda M; Ota H; Kazama K; Naoe T; Kawazoe Y; Ichikawa S; Kondo H; Yokokura T
Distribution of TNF endogenously induced by various immunopotentiators and Lactobacillus casei in mice.
In vivo (Athens, Greece) 1992;6(3):247-53.
1992: Kohda K; Terashima I; Sawada N; Nozaki I; Yasuda M; Kawazoe Y
Synthesis and O-demethylation rate of cis-[Pt(NH3)2(O6,9-dimethylguanine-7)2]Cl2: a study of the demethylation mechanism of O6-methylguanine-DNA methyltransferase.
Chemical research in toxicology 1992;5(1):8-9.
1992: Sakagami H; Konno K; Kawazoe Y; Lai P; Nonoyama M
Multiple immunological functions of extracts from the cone of Japanese white pine, Pinus parviflora Sieb. et Zucc.
Advances in experimental medicine and biology 1992;319():331-5.
1991: Suzuki M; Takahashi K; Kawazoe Y; Sakumi K; Sekiguchi M
Inhibitory effect of cadmium and mercury ions on transcription of the ada gene.
Biochemical and biophysical research communications 1991;179(3):1517-21.
1991: Kohda K; Kawazoe Y; Minoura Y; Tada M
Separation and identification of N4-(guanosin-7-yl)-4-aminoquinoline 1-oxide, a novel nucleic acid adduct of carcinogen 4-nitroquinoline 1-oxide.
Carcinogenesis 1991;12(8):1523-5.
1991: Ohta Y; Takahashi K; Kohda K; Kawazoe Y
Some cytotoxicological aspects of ethyl and fluoroethyl alkanesulfonates in Escherichia coli: role of fluorine substitution.
Chemical & pharmaceutical bulletin 1991;39(6):1510-2.
1991: Sakagami H; Oh-hara T; Kohda K; Kawazoe Y
Lignified materials as a potential medicinal resource. IV. Dehydrogenation polymers of some phenylpropenoids and their capacity to stimulate polymorphonuclear cell iodination.
Chemical & pharmaceutical bulletin 1991;39(4):950-5.
1991: Kohda K; Sawada N; Kawazoe Y
Formation of O6,7-dimethylguanine residues in calf thymus deoxyribonucleic acid treated with carcinogenic N-methyl-N-nitrosourea in vitro.
Chemical & pharmaceutical bulletin 1991;39(3):801-2.
1991: Kikuchi K; Sakagami H; Fujinaga S; Kawazoe Y; Oh-Hara T; Ichikawa S; Kurakata Y; Takeda M; Sato T
Stimulation of mouse peritoneal macrophages by lignin-related substances.
Anticancer research 1991;11(2):841-5.
1991: Sakagami H; Kawazoe Y; Oh-hara T; Kitajima K; Inoue Y; Tanuma S; Ichikawa S; Konno K
Stimulation of human peripheral blood polymorphonuclear cell iodination by lignin-related substances.
Journal of leukocyte biology 1991;49(3):277-82.
1991: Sarai K; Kohda K; Hayatsu H; Miyamae T; Kawazoe Y
Potentiation of bleomycin cytotoxicity in cultured mammalian cells by polyacrylic acid. III. Induction of DNA strand breakage and suppression of cellular heat production.
Anticancer research 1991;11(2):957-60.
1991: Suzuki T; Sarai K; Kohda K; Kawazoe Y
Potentiation of bleomycin cytotoxicity by high molecular weight polyacrylic acid. II. Involvement of rapid conformational change of polyacrylate.
Anticancer research 1991;11(2):953-6.
1991: Sakagami H; Kawazoe Y; Komatsu N; Simpson A; Nonoyama M; Konno K; Yoshida T; Kuroiwa Y; Tanuma S
Antitumor, antiviral and immunopotentiating activities of pine cone extracts: potential medicinal efficacy of natural and synthetic lignin-related materials (review).
Anticancer research 1991;11(2):881-8.
1991: Takahashi K; Imaeda T; Kawazoe Y
Inhibitory effect of cadmium and mercury ions on induction of the adaptive response in Escherichia coli.
Mutation research 1991;254(1):45-53.
1991: Kohda K; Yasuda M; Sawada N; Itano K; Kawazoe Y
Dealkylation rates of O6-alkyldeoxyguanosine, O4-alkylthymidine and related compounds in an alkyl-transfer system.
Chemico-biological interactions 1991;78(1):23-32.
1990: Sakagami H; Nagata K; Ishihama A; Oh-hara T; Kawazoe Y
Anti-influenza virus activity of synthetically polymerized phenylpropenoids.
Biochemical and biophysical research communications 1990;172(3):1267-72.
1990: Sakagami H; Kohno S; Tanuma S; Kawazoe Y
Induction of cytotoxic factor in mice by lignified materials combined with OK-432 (Picibanil).
In vivo (Athens, Greece) 1990;4(6):371-5.
1990: Kohda K; Nakagawa T; Kawazoe Y
Singlet oxygen takes part in 8-hydroxydeoxyguanosine formation in deoxyribonucleic acid treated with the horseradish peroxidase-H2O2 system.
Chemical & pharmaceutical bulletin 1990;38(11):3072-5.
1990: Oh-hara T; Kawazoe Y; Sakagami H
Lignified materials as potential medicinal resources. III. Diversity of biological activity and possible molecular species involved.
Chemical & pharmaceutical bulletin 1990;38(11):3031-4.
1990: Kurakata Y; Sakagami H; Oh-Hara T; Kawazoe Y; Asano K; Fujinaga S; Takeda M; Sato T
Mitogenic activity of natural and synthetic lignins against cultured splenocytes.
In vivo (Athens, Greece) 1990;4(6):377-80.
1990: Oh-Hara T; Sakagami H; Kawazoe Y; Momoi T; Kaiya T; Kohda K; Komatsu N; Ohsawa N; Fujimaki M; Konno K
Lignified materials as potential medicinal resources. II. Prevention of pathogenic bacterial infections in mice.
In vivo (Athens, Greece) 1990;4(4):221-3.
1990: Suzuki T; Kohda K; Kawazoe Y
Potentiation of bleomycin cytotoxicity in cultured mammalian cells by high molecular weight polyacrylic acid.
Anticancer research 1990;10(4):1001-4.
1990: Takahashi K; Sekiguchi M; Kawazoe Y
Effects of vanillin and o-vanillin on induction of DNA-repair networks: modulation of mutagenesis in Escherichia coli.
Mutation research 1990;230(2):127-34.
1990: Oh-Hara T; Ikeda Y; Sakagami H; Konno K; Kaiya T; Kohda K; Kawazoe Y
Lignified natural products as potential medicinal resources. I. Potentiation of hemolytic plaque-forming cell production in mice.
Chemical & pharmaceutical bulletin 1990;38(1):282-4.
1990: Oh-Hara T; Sakagami H; Kawazoe Y; Kaiya T; Komatsu N; Ohsawa N; Fujimaki M; Tanuma S; Konno K
Antimicrobial spectrum of lignin-related pine cone extracts of Pinus parviflora Sieb. et Zucc.
In vivo (Athens, Greece) 1990;4(1):7-12.
1990: Suzuki T; Kohda K; Kawazoe Y
Potentiation of bleomycin cytotoxicity by polyhydric alcohols.
Anticancer research 1990;10(1):97-103.
1989: Kohda K; Ohta Y; Kawazoe Y; Kato T; Suzumura Y; Hamada Y; Shioiri T
Ulicyclamide is cytotoxic against L1210 cells in vitro and inhibits both DNA and RNA syntheses.
Biochemical pharmacology 1989;38(24):4500-2.
1989: Kohda K; Ohta Y; Yokoyama Y; Kawazoe Y; Kato T; Suzumura Y; Hamada Y; Shioiri T
Mechanistic aspects of the cytocidal action of ulithiacyclamide on mouse leukemia L1210 cells in vitro.
Biochemical pharmacology 1989;38(24):4497-500.
1989: Sakagami H; Oh-Hara T; Kaiya T; Kawazoe Y; Nonoyama M; Konno K
Molecular species of the antitumor and antiviral fraction from pine cone extract.
Anticancer research 1989;9(6):1593-8.
1989: Takahashi K; Sekiguchi M; Kawazoe Y
A specific inhibition of induction of adaptive response by o-vanillin, a potent comutagen.
Biochemical and biophysical research communications 1989;162(3):1376-81.
1989: Fukuchi K; Sakagami H; Ikeda M; Kawazoe Y; Oh-Hara T; Konno K; Ichikawa S; Hata N; Kondo H; Nonoyama M
Inhibition of herpes simplex virus infection by pine cone antitumor substances.
Anticancer research 1989;9(2):313-7.
1988: Takahashi K; Imaeda T; Kawazoe Y
Effect of metal ions on the adaptive response induced by N-methyl-N-nitrosourea in Escherichia coli.
Biochemical and biophysical research communications 1988;157(3):1124-30.
1988: Takahashi K; Kohda K; Oh-hara T; Sekiguchi M; Kawazoe Y
Structural requirement for the induction of the adaptive response in Escherichia coli among N-(substituted alkyl)-N-nitrosoureas.
Mutation research 1988;202(1):193-201.
1988: Takahashi K; Kawazoe Y; Sakumi K; Nakabeppu Y; Sekiguchi M
Activation of Ada protein as a transcriptional regulator by direct alkylation with methylating agents.
The Journal of biological chemistry 1988;263(27):13490-2.
1987: Kohda K; Tada M; Hakura A; Kasai H; Kawazoe Y
Formation of 8-hydroxyguanine residues in DNA treated with 4-hydroxyaminoquinoline 1-oxide and its related compounds in the presence of seryl-AMP.
Biochemical and biophysical research communications 1987;149(3):1141-8.
1987: Takahashi K; Kawazoe Y
Potent induction of the adaptive response by a weak mutagen, methyl iodide, in Escherichia coli.
Mutation research 1987;180(2):163-9.
1987: Hakura A; Kohda K; Kawazoe Y
Inhibitory effect of heavy water on mutability of chemically injured Escherichia coli cells.
Mutation research 1987;180(2):155-61.

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