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Christopher Bagley

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Krzysztof M Mrozik; Peter S Zilm; Christopher J Bagley; Sandra Hack; Peter Hoffmann; Stan Gronthos; P Mark Bartold
Proteomic characterization of mesenchymal stem cell-like populations derived from ovine periodontal ligament, dental pulp, and bone marrow: analysis of differentially expressed proteins.
Abiodun D Ogunniyi; Layla K Mahdi; Michael P Jennings; Alastair G McEwan; Christopher A McDevitt; Mark B Van der Hoek; Christopher J Bagley; Peter Hoffmann; Katherine A Gould; James C Paton
Central role of manganese in regulation of stress responses, physiology, and metabolism in Streptococcus pneumoniae.
Mark R Condina; Johan O R Gustafsson; Manuela Klingler-Hoffmann; Christopher J Bagley; Shaun R McColl; Peter Hoffmann
EZYprep LC-coupled MALDI-TOF/TOF MS: an improved matrix spray application for phosphopeptide characterisation.

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All Publications

2010: Krzysztof M Mrozik; Peter S Zilm; Christopher J Bagley; Sandra Hack; Peter Hoffmann; Stan Gronthos; P Mark Bartold
Proteomic characterization of mesenchymal stem cell-like populations derived from ovine periodontal ligament, dental pulp, and bone marrow: analysis of differentially expressed proteins.
Stem cells and development 2010;19(10):1485-99.
2010: Abiodun D Ogunniyi; Layla K Mahdi; Michael P Jennings; Alastair G McEwan; Christopher A McDevitt; Mark B Van der Hoek; Christopher J Bagley; Peter Hoffmann; Katherine A Gould; James C Paton
Central role of manganese in regulation of stress responses, physiology, and metabolism in Streptococcus pneumoniae.
Journal of bacteriology 2010;192(17):4489-97.
2010: Mark R Condina; Johan O R Gustafsson; Manuela Klingler-Hoffmann; Christopher J Bagley; Shaun R McColl; Peter Hoffmann
EZYprep LC-coupled MALDI-TOF/TOF MS: an improved matrix spray application for phosphopeptide characterisation.
Proteomics 2010;10(13):2516-30.
2010: Peter S Zilm; Alex Mira; Christopher J Bagley; Anthony H Rogers
Effect of alkaline growth pH on the expression of cell envelope proteins in Fusobacterium nucleatum.
Microbiology (Reading, England) 2010;156(Pt 6):1783-94.
2009: Hayley J Andreazza; Tianfang Wang; Christopher J Bagley; Peter Hoffmann; John H Bowie
Negative ion fragmentations of deprotonated peptides. The unusual case of isoAsp: a joint experimental and theoretical study. Comparison with positive ion cleavages.
Rapid communications in mass spectrometry : RCM 2009;23(13):1993-2002.
2008: Luke A Miles; Kwok S Wun; Gabriela A N Crespi; Michelle T Fodero-Tavoletti; Denise Galatis; Christopher J Bagley; Konrad Beyreuther; Colin L Masters; Roberto Cappai; William J McKinstry; Kevin J Barnham; Michael W Parker
Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
Journal of molecular biology 2008;377(1):181-92.
2007: Jui T Ho; John G Lewis; Peter O'Loughlin; Christopher J Bagley; Roberto Romero; Gus A Dekker; David Torpy
Reduced maternal corticosteroid-binding globulin and cortisol levels in pre-eclampsia and gamete recipient pregnancies.
Clinical endocrinology 2007;66(6):869-77.
2007: Peter S Zilm; Christopher J Bagley; Anthony H Rogers; Ian R Milne; Neville J Gully
The proteomic profile of Fusobacterium nucleatum is regulated by growth pH.
Microbiology (Reading, England) 2007;153(Pt 1):148-59.
2006: Catherine M Sutherland; Paul A B Moretti; Niamh M Hewitt; Christopher J Bagley; Mathew A Vadas; Stuart M Pitson
The calmodulin-binding site of sphingosine kinase and its role in agonist-dependent translocation of sphingosine kinase 1 to the plasma membrane.
The Journal of biological chemistry 2006;281(17):11693-701.
2006: Jui T Ho; H Al-Musalhi; M J Chapman; T Quach; P D Thomas; Christopher J Bagley; John G Lewis; David Torpy
Septic shock and sepsis: a comparison of total and free plasma cortisol levels.
The Journal of clinical endocrinology and metabolism 2006;91(1):105-14.
2005: John G Lewis; Christopher J Bagley; Peter A Elder; Anthony W Bachmann; David Torpy
Plasma free cortisol fraction reflects levels of functioning corticosteroid-binding globulin.
Clinica chimica acta; international journal of clinical chemistry 2005;359(1-2):189-94.
2004: E Mitchell; David Torpy; Christopher J Bagley
Pregnancy-associated corticosteroid-binding globulin: high resolution separation of glycan isoforms.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(6):357-9.
2003: Barbara J McClure; Tim Hercus; Bronwyn A Cambareri; Joanna M Woodcock; Christopher J Bagley; Geoff J Howlett; Angel F Lopez
Molecular assembly of the ternary granulocyte-macrophage colony-stimulating factor receptor complex.
Blood 2003;101(4):1308-15.
2002: Stuart M Pitson; Paul A B Moretti; Julia R Zebol; Reza Zareie; Claudia K Derian; Andrew L Darrow; Jenson Qi; Richard J D'Andrea; Christopher J Bagley; Mathew A Vadas; Binks W Wattenberg
The nucleotide-binding site of human sphingosine kinase 1.
The Journal of biological chemistry 2002;277(51):49545-53.
2001: K L Jones; Christopher J Bagley; Carolyn M Butcher; S C Barry; Mathew A Vadas; Richard J D'Andrea
Peptide insertions in domain 4 of hbeta(c), the shared signalling receptor subunit for GM-CSF, IL3 and IL5, induce ligand-independent activation.
Cytokine 2001;14(6):303-15.
2001: Christopher J Bagley; Joanna M Woodcock; Mark A Guthridge; Frank C Stomski; Angel F Lopez
Structural and functional hot spots in cytokine receptors.
International journal of hematology 2001;73(3):299-307.
2001: Hayley Ramshaw; Joanna M Woodcock; Christopher J Bagley; Barbara J McClure; Tim Hercus; Angel F Lopez
New approaches in the treatment of asthma.
Immunology and cell biology 2001;79(2):154-9.
2000: Jamie Rossjohn; William J McKinstry; Joanna M Woodcock; Barbara J McClure; Tim Hercus; Michael W Parker; Angel F Lopez; Christopher J Bagley
Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common beta-chain bound to an antagonist.
Blood 2000;95(8):2491-8.
2000: Terrence D Mulhern; Angel F Lopez; Richard J D'Andrea; C Gaunt; L Vandeleur; Mathew A Vadas; Grant W Booker; Christopher J Bagley
The solution structure of the cytokine-binding domain of the common beta-chain of the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 and interleukin-5.
Journal of molecular biology 2000;297(4):989-1001.
1999: Joanna M Woodcock; Christopher J Bagley; Angel F Lopez
The functional basis of granulocyte-macrophage colony stimulating factor, interleukin-3 and interleukin-5 receptor activation, basic and clinical implications.
The international journal of biochemistry & cell biology 1999;31(10):1017-25.
1999: Q Sun; K Jones; Barbara J McClure; B Cambareri; B Zacharakis; PO Iversen; Frank C Stomski; Joanna M Woodcock; Christopher J Bagley; Richard J D'Andrea; Angel F Lopez
Simultaneous antagonism of interleukin-5, granulocyte-macrophage colony-stimulating factor, and interleukin-3 stimulation of human eosinophils by targetting the common cytokine binding site of their receptors.
Blood 1999;94(6):1943-51.
1999: Frank C Stomski; Mara Dottore; W Winnall; Mark A Guthridge; Joanna M Woodcock; Christopher J Bagley; D T Thomas; R K Andrews; Michael C Berndt; Angel F Lopez
Identification of a 14-3-3 binding sequence in the common beta chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM-CSF.
Blood 1999;94(6):1933-42.
1999: Terrence D Mulhern; Christopher J Bagley; C Gaunt; Angel F Lopez; Mathew A Vadas; Richard J D'Andrea; Grant W Booker
1H and 15N chemical shift assignments for domain 4 of the common beta-chain of the IL-3, IL-5 and GM-CSF receptors.
Journal of biomolecular NMR 1999;14(3):281-2.
1998: Frank C Stomski; Joanna M Woodcock; B Zacharakis; Christopher J Bagley; Q Sun; Angel F Lopez
Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three receptors.
The Journal of biological chemistry 1998;273(2):1192-9.
1998: Mark A Guthridge; Frank C Stomski; D Thomas; Joanna M Woodcock; Christopher J Bagley; Michael C Berndt; Angel F Lopez
Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors.
Stem cells (Dayton, Ohio) 1998;16(5):301-13.
1997: Joanna M Woodcock; Barbara J McClure; Frank C Stomski; M J Elliott; Christopher J Bagley; Angel F Lopez
The human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor exists as a preformed receptor complex that can be activated by GM-CSF, interleukin-3, or interleukin-5.
Blood 1997;90(8):3005-17.
1997: Joanna M Woodcock; Christopher J Bagley; Angel F Lopez
Receptors of the cytokine superfamily: mechanisms of activation and involvement in disease.
Baillière's clinical haematology 1997;10(3):507-24.
1997: Christopher J Bagley; Angel F Lopez; Mathew A Vadas
New frontiers for IL-5.
The Journal of allergy and clinical immunology 1997;99(6 Pt 1):725-8.
1997: Christopher J Bagley; Joanna M Woodcock; Frank C Stomski; Angel F Lopez
The structural and functional basis of cytokine receptor activation: lessons from the common beta subunit of the granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5 receptors.
Blood 1997;89(5):1471-82.
1996: Christopher J Bagley; J Phillips; B Cambareri; Mathew A Vadas; Angel F Lopez
A discontinuous eight-amino acid epitope in human interleukin-3 binds the alpha-chain of its receptor.
The Journal of biological chemistry 1996;271(50):31922-8.
1996: Brendan J Jenkins; Christopher J Bagley; J Woodcock; Angel F Lopez; Thomas J Gonda
Interacting residues in the extracellular region of the common beta subunit of the human granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptors involved in constitutive activation.
The Journal of biological chemistry 1996;271(47):29707-14.
1996: Joanna M Woodcock; Christopher J Bagley; B Zacharakis; Angel F Lopez
A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all three ligands.
The Journal of biological chemistry 1996;271(42):25999-6006.
1996: Frank C Stomski; Q Sun; Christopher J Bagley; J Woodcock; G Goodall; R K Andrews; M C Berndt; Angel F Lopez
Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity binding.
Molecular and cellular biology 1996;16(6):3035-46.
1996: Q Sun; Joanna M Woodcock; Aaron P Rapoport; Frank C Stomski; E I Korpelainen; Christopher J Bagley; G J Goodall; W B Smith; Jennifer R Gamble; Mathew A Vadas; Angel F Lopez
Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist.
Blood 1996;87(1):83-92.
1995: Christopher J Bagley; Joanna M Woodcock; Tim Hercus; M Frances Shannon; Angel F Lopez
Interaction of GM-CSF and IL-3 with the common beta-chain of their receptors.
Journal of leukocyte biology 1995;57(5):739-46.
1994: Joanna M Woodcock; B Zacharakis; G Plaetinck; Christopher J Bagley; S Qiyu; Tim Hercus; J Tavernier; Angel F Lopez
Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF.
The EMBO journal 1994;13(21):5176-85.
1994: Tim Hercus; Christopher J Bagley; B Cambareri; M Dottore; Joanna M Woodcock; Mathew A Vadas; M Frances Shannon; Angel F Lopez
Specific human granulocyte-macrophage colony-stimulating factor antagonists.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):5838-42.
1994: Tim Hercus; B Cambareri; M Dottore; J Woodcock; Christopher J Bagley; Mathew A Vadas; M Frances Shannon; Angel F Lopez
Identification of residues in the first and fourth helices of human granulocyte-macrophage colony-stimulating factor involved in biologic activity and in binding to the alpha- and beta-chains of its receptor.
Blood 1994;83(12):3500-8.
1994: S C Barry; Christopher J Bagley; J Phillips; M Dottore; B Cambareri; P Moretti; Richard J D'Andrea; G J Goodall; M Frances Shannon; Mathew A Vadas
Two contiguous residues in human interleukin-3, Asp21 and Glu22, selectively interact with the alpha- and beta-chains of its receptor and participate in function.
The Journal of biological chemistry 1994;269(11):8488-92.
1993: G J Goodall; Christopher J Bagley; Mathew A Vadas; Angel F Lopez
A model for the interaction of the GM-CSF, IL-3 and IL-5 receptors with their ligands.
Growth factors (Chur, Switzerland) 1993;8(2):87-97.