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Michael Keane

Research Profile

Chemicals & Drugs

Disorders

Living Beings

Anatomy

Procedures

Lung Transplantation

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TOP 3
Vyacheslav Palchevskiy; Nastran Hashemi; S Sam Weigt; Ying Ying Xue; Ariss Derhovanessian; Michael P Keane; Robert M Strieter; Michael C Fishbein; Jane C Deng; Joseph P Lynch; Robert Elashoff; John A Belperio
Immune response CC chemokines CCL2 and CCL5 are associated with pulmonary sarcoidosis.
A Busuttil; S Sam Weigt; Michael P Keane; Ying Ying Xue; V Palchevskiy; Marie D Burdick; C Huang; David A Zisman; Michael C Fishbein; Joseph P Lynch; Robert M Strieter; Robert Elashoff; John A Belperio
CXCR3 ligands are augmented during the pathogenesis of pulmonary sarcoidosis.
S Sam Weigt; Robert Elashoff; C Huang; Abbas Ardehali; Aric Gregson; Bernard M Kubak; Michael C Fishbein; Rajan Saggar; Michael P Keane; R Saggar; Joseph P Lynch; David A Zisman; David J Ross; John A Belperio
Aspergillus colonization of the lung allograft is a risk factor for bronchiolitis obliterans syndrome.

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All Publications

2011: Vyacheslav Palchevskiy; Nastran Hashemi; S Sam Weigt; Ying Ying Xue; Ariss Derhovanessian; Michael P Keane; Robert M Strieter; Michael C Fishbein; Jane C Deng; Joseph P Lynch; Robert Elashoff; John A Belperio
Immune response CC chemokines CCL2 and CCL5 are associated with pulmonary sarcoidosis.
Fibrogenesis & tissue repair 2011;4():10.
2009: A Busuttil; S Sam Weigt; Michael P Keane; Ying Ying Xue; V Palchevskiy; Marie D Burdick; C Huang; David A Zisman; Michael C Fishbein; Joseph P Lynch; Robert M Strieter; Robert Elashoff; John A Belperio
CXCR3 ligands are augmented during the pathogenesis of pulmonary sarcoidosis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2009;34(3):676-86.
2009: S Sam Weigt; Robert Elashoff; C Huang; Abbas Ardehali; Aric Gregson; Bernard M Kubak; Michael C Fishbein; Rajan Saggar; Michael P Keane; R Saggar; Joseph P Lynch; David A Zisman; David J Ross; John A Belperio
Aspergillus colonization of the lung allograft is a risk factor for bronchiolitis obliterans syndrome.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(8):1903-11.
2009: Thanh N Huynh; S Sam Weigt; John A Belperio; Mary Territo; Michael P Keane
Outcome and prognostic indicators of patients with hematopoietic stem cell transplants admitted to the intensive care unit.
Journal of transplantation 2009;2009():917294.
2008: Rajan Saggar; David J Ross; R Saggar; David A Zisman; Aric Gregson; J P Lynch; Michael P Keane; S Sam Weigt; Abbas Ardehali; Bernard M Kubak; C Lai; David Elashoff; Michael C Fishbein; William D Wallace; John A Belperio
Pulmonary hypertension associated with lung transplantation obliterative bronchiolitis and vascular remodeling of the allograft.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(9):1921-30.
2008: S Sam Weigt; Robert Elashoff; Michael P Keane; Robert M Strieter; B N Gomperts; Ying Ying Xue; Abbas Ardehali; Aric Gregson; Bernard M Kubak; Michael C Fishbein; Rajan Saggar; David J Ross; Joseph P Lynch; David A Zisman; John A Belperio
Altered levels of CC chemokines during pulmonary CMV predict BOS and mortality post-lung transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(7):1512-22.
2007: David A Zisman; Arun S Karlamangla; David J Ross; Michael P Keane; John A Belperio; Rajan Saggar; Joseph P Lynch; Abbas Ardehali; Jonathan G Goldin
High-resolution chest CT findings do not predict the presence of pulmonary hypertension in advanced idiopathic pulmonary fibrosis.
Chest 2007;132(3):773-9.
2007: Kurt M Hong; John A Belperio; Michael P Keane; Marie D Burdick; Robert M Strieter
Differentiation of human circulating fibrocytes as mediated by transforming growth factor-beta and peroxisome proliferator-activated receptor gamma.
The Journal of biological chemistry 2007;282(31):22910-20.
2007: Borna Mehrad; Michael P Keane; Brigitte N Gomperts; Robert M Strieter
Circulating progenitor cells in chronic lung disease.
Expert review of respiratory medicine 2007;1(1):157-65.
2007: Brigitte N Gomperts; John A Belperio; Michael C Fishbein; Michael P Keane; Marie D Burdick; Robert M Strieter
Keratinocyte growth factor improves repair in the injured tracheal epithelium.
American journal of respiratory cell and molecular biology 2007;37(1):48-56.
2007: Borna Mehrad; Michael P Keane; Robert M Strieter
Chemokines as mediators of angiogenesis.
Thrombosis and haemostasis 2007;97(5):755-62.
2007: Robert M Strieter; Brigitte N Gomperts; Michael P Keane
The role of CXC chemokines in pulmonary fibrosis.
The Journal of clinical investigation 2007;117(3):549-56.
2007: Borna Mehrad; Marie D Burdick; David A Zisman; Michael P Keane; John A Belperio; Robert M Strieter
Circulating peripheral blood fibrocytes in human fibrotic interstitial lung disease.
Biochemical and biophysical research communications 2007;353(1):104-8.
2007: Michael P Keane; Brigitte N Gomperts; S Sam Weigt; Ying Ying Xue; Marie D Burdick; Hiromi Nakamura; David A Zisman; Abbas Ardehali; Rajan Saggar; Joseph P Lynch; Cory M Hogaboam; Steven Kunkel; Nicholas W Lukacs; David J Ross; Michael J Grusby; Robert M Strieter; John A Belperio
IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndrome.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(1):511-9.
2006: Michael P Keane; Robert M Strieter; Joseph P Lynch; John A Belperio
Inflammation and angiogenesis in fibrotic lung disease.
Seminars in respiratory and critical care medicine 2006;27(6):589-99.
2006: Virender K Rehan; Sharon Sugano; Ying Wang; Jamie Santos; Sonia Romero; Chiranjib Dasgupta; Michael P Keane; Mildred T Stahlman; John S Torday
Evidence for the presence of lipofibroblasts in human lung.
Experimental lung research 2006;32(8):379-93.
2006: John A Belperio; Michael P Keane; Joseph P Lynch; Robert M Strieter
The role of cytokines during the pathogenesis of ventilator-associated and ventilator-induced lung injury.
Seminars in respiratory and critical care medicine 2006;27(4):350-64.
2006: Fernando J Martinez; Michael P Keane
Update in diffuse parenchymal lung diseases 2005.
American journal of respiratory and critical care medicine 2006;173(10):1066-71.
2006: Robert M Strieter; Marie D Burdick; Javier Mestas; Brigitte N Gomperts; Michael P Keane; John A Belperio
Cancer CXC chemokine networks and tumour angiogenesis.
European journal of cancer (Oxford, England : 1990) 2006;42(6):768-78.
2005: Robert M Strieter; Marie D Burdick; Brigitte N Gomperts; John A Belperio; Michael P Keane
CXC chemokines in angiogenesis.
Cytokine & growth factor reviews 2005;16(6):593-609.
2005: John A Belperio; Michael P Keane; Marie D Burdick; Brigitte N Gomperts; Ying Ying Xue; Kurt Hong; Javier Mestas; David A Zisman; Abbas Ardehali; Rajan Saggar; Joseph P Lynch; David J Ross; Robert M Strieter
CXCR2/CXCR2 ligand biology during lung transplant ischemia-reperfusion injury.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6931-9.
2005: Vedang A Londhe; John A Belperio; Michael P Keane; Marie D Burdick; Ying Ying Xue; Robert M Strieter
CXCR2/CXCR2 ligand biological axis impairs alveologenesis during dsRNA-induced lung inflammation in mice.
Pediatric research 2005;58(5):919-26.
2005: Roderick J Phillips; Javier Mestas; Mehrnaz Gharaee-Kermani; Marie D Burdick; Antonio Sica; John A Belperio; Michael P Keane; Robert M Strieter
Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha.
The Journal of biological chemistry 2005;280(23):22473-81.
2005: Robert M Strieter; Michael P Keane; Marie D Burdick; Ammar Sakkour; Lynne Murray; John A Belperio
The role of CXCR2/CXCR2 ligands in acute lung injury.
Current drug targets. Inflammation and allergy 2005;4(3):299-303.
2005: John A Belperio; Michael P Keane; Marie D Burdick; Brigitte N Gomperts; Ying Ying Xue; Kurt Hong; Javier Mestas; Abbas Ardehali; Borna Mehrad; Rajan Saggar; Joseph P Lynch; David J Ross; Robert M Strieter
Role of CXCR2/CXCR2 ligands in vascular remodeling during bronchiolitis obliterans syndrome.
The Journal of clinical investigation 2005;115(5):1150-62.
2005: Robert M Strieter; John A Belperio; Marie D Burdick; Michael P Keane
CXC chemokines in angiogenesis relevant to chronic fibroproliferation.
Current drug targets. Inflammation and allergy 2005;4(1):23-6.
2005: Marie D Burdick; Lynne Murray; Michael P Keane; Ying Ying Xue; David A Zisman; John A Belperio; Robert M Strieter
CXCL11 attenuates bleomycin-induced pulmonary fibrosis via inhibition of vascular remodeling.
American journal of respiratory and critical care medicine 2005;171(3):261-8.
2005: Michael P Keane; Robert M Strieter; John A Belperio
Mechanisms and mediators of pulmonary fibrosis.
Critical reviews in immunology 2005;25(6):429-63.
2005: David A Zisman; Michael P Keane; John A Belperio; Robert M Strieter; Joseph P Lynch
Pulmonary fibrosis.
Methods in molecular medicine 2005;117():3-44.
2004: Robert M Strieter; John A Belperio; Marie D Burdick; Sherven Sharma; Steven M Dubinett; Michael P Keane
CXC chemokines: angiogenesis, immunoangiostasis, and metastases in lung cancer.
Annals of the New York Academy of Sciences 2004;1028():351-60.
2004: John A Belperio; Maria Dy; Lynne Murray; Marie D Burdick; Ying Ying Xue; Robert M Strieter; Michael P Keane
The role of the Th2 CC chemokine ligand CCL17 in pulmonary fibrosis.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(7):4692-8.
2004: Roderick J Phillips; Marie D Burdick; Kurt Hong; Marin A Lutz; Lynne Murray; Ying Ying Xue; John A Belperio; Michael P Keane; Robert M Strieter
Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis.
The Journal of clinical investigation 2004;114(3):438-46.
2004: Ling Zhang; Michael P Keane; Li X Zhu; Sherven Sharma; Enrique Rozengurt; Robert M Strieter; Steven M Dubinett; Min Huang
Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis.
The Journal of biological chemistry 2004;279(27):28315-9.
2004: Robert M Strieter; Michael P Keane
Innate immunity dictates cytokine polarization relevant to the development of pulmonary fibrosis.
The Journal of clinical investigation 2004;114(2):165-8.
2004: Robert M Strieter; John A Belperio; Roderick J Phillips; Michael P Keane
CXC chemokines in angiogenesis of cancer.
Seminars in cancer biology 2004;14(3):195-200.
2004: Michael P Keane; Marie D Burdick; Ying Ying Xue; Marin Lutz; John A Belperio; Robert M Strieter
The chemokine receptor, CXCR2, mediates the tumorigenic effects of ELR+ CXC chemokines.
Chest 2004;125(5 Suppl):133S.
2004: Richard D Sue; John A Belperio; Marie D Burdick; Lynne Murray; Ying Ying Xue; Maria Dy; Jeffery J Kwon; Michael P Keane; Robert M Strieter
CXCR2 is critical to hyperoxia-induced lung injury.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(6):3860-8.
2004: Michael P Keane; John A Belperio; Ying Ying Xue; Marie D Burdick; Robert M Strieter
Depletion of CXCR2 inhibits tumor growth and angiogenesis in a murine model of lung cancer.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):2853-60.
2004: Robert M Strieter; John A Belperio; Roderick J Phillips; Michael P Keane
Chemokines: angiogenesis and metastases in lung cancer.
Novartis Foundation symposium 2004;256():173-84; discussion 184-8, 259-69.
2003: John A Belperio; Michael P Keane; Marie D Burdick; Joseph P Lynch; David A Zisman; Ying Ying Xue; Kewang Li; Abbas Ardehali; David J Ross; Robert M Strieter
Role of CXCL9/CXCR3 chemokine biology during pathogenesis of acute lung allograft rejection.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4844-52.
2003: John A Belperio; Kathleen Lake; Henry D Tazelaar; Michael P Keane; Robert M Strieter; Joseph P Lynch
Bronchiolitis obliterans syndrome complicating lung or heart-lung transplantation.
Seminars in respiratory and critical care medicine 2003;24(5):499-530.
2003: Robert M Strieter; John A Belperio; Michael P Keane
CXC chemokines in vascular remodeling related to pulmonary fibrosis.
American journal of respiratory cell and molecular biology 2003;29(3 Suppl):S67-9.
2003: Claudia Jakubzick; Esther S Choi; Bharat H Joshi; Michael P Keane; Steven Kunkel; Raj K Puri; Cory M Hogaboam
Therapeutic attenuation of pulmonary fibrosis via targeting of IL-4- and IL-13-responsive cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(5):2684-93.
2003: Roderick J Phillips; Marie D Burdick; Marin Lutz; John A Belperio; Michael P Keane; Robert M Strieter
The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases.
American journal of respiratory and critical care medicine 2003;167(12):1676-86.
2003: Robert M Strieter; John A Belperio; Michael P Keane
Host innate defenses in the lung: the role of cytokines.
Current opinion in infectious diseases 2003;16(3):193-8.
2003: Robert M Strieter; Marie D Burdick; John A Belperio; Michael P Keane
Measurement of chemokines at the protein level in tissue.
Methods in molecular medicine 2003;78():377-88.
2002: Robert M Strieter; John A Belperio; Michael P Keane
CXC chemokines in angiogenesis related to pulmonary fibrosis.
Chest 2002;122(6 Suppl):298S-301S.
2002: John A Belperio; Michael P Keane; Marie D Burdick; Vedang A Londhe; Ying Ying Xue; Kewang Li; Roderick J Phillips; Robert M Strieter
Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injury.
The Journal of clinical investigation 2002;110(11):1703-16.
2002: Michael P Keane; Seamas C Donnelly; John A Belperio; Richard B Goodman; Maria Dy; Marie D Burdick; Michael C Fishbein; Robert M Strieter
Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(11):6515-21.
2002: John A Belperio; Maria Dy; Marie D Burdick; Ying Ying Xue; Kewang Li; Jack A Elias; Michael P Keane
Interaction of IL-13 and C10 in the pathogenesis of bleomycin-induced pulmonary fibrosis.
American journal of respiratory cell and molecular biology 2002;27(4):419-27.
2002: John A Belperio; Michael P Keane; Marie D Burdick; Joseph P Lynch; Ying Ying Xue; Kewang Li; David J Ross; Robert M Strieter
Critical role for CXCR3 chemokine biology in the pathogenesis of bronchiolitis obliterans syndrome.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(2):1037-49.
2002: Min Huang; Sherven Sharma; Li X Zhu; Michael P Keane; Jie Luo; Ling Zhang; Marie D Burdick; Ying Q Lin; Mariam Dohadwala; Brian Gardner; Raj K Batra; Robert M Strieter; Steven M Dubinett
IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis.
The Journal of clinical investigation 2002;109(7):931-7.
2002: Robert M Strieter; John A Belperio; Michael P Keane
Cytokines in innate host defense in the lung.
The Journal of clinical investigation 2002;109(6):699-705.
2002: John A Belperio; Bruno DiGiovine; Michael P Keane; Marie D Burdick; Ying Ying Xue; David J Ross; Joseph P Lynch; Steven Kunkel; Robert M Strieter
Interleukin-1 receptor antagonist as a biomarker for bronchiolitis obliterans syndrome in lung transplant recipients.
Transplantation 2002;73(4):591-9.
2002: Michael P Keane; Robert M Strieter
The importance of balanced pro-inflammatory and anti-inflammatory mechanisms in diffuse lung disease.
Respiratory research 2002;3():5.
2001: Michael P Keane; John A Belperio; Marie D Burdick; Joseph P Lynch; M C Fishbein; Robert M Strieter
ENA-78 is an important angiogenic factor in idiopathic pulmonary fibrosis.
American journal of respiratory and critical care medicine 2001;164(12):2239-42.
2001: John A Belperio; Michael P Keane; Marie D Burdick; Joseph P Lynch; Ying Ying Xue; A Berlin; David J Ross; Steven Kunkel; I F Charo; Robert M Strieter
Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome.
The Journal of clinical investigation 2001;108(4):547-56.
2001: Michael P Keane; John A Belperio; Marie D Burdick; Robert M Strieter
IL-12 attenuates bleomycin-induced pulmonary fibrosis.
American journal of physiology. Lung cellular and molecular physiology 2001;281(1):L92-7.
2000: John A Belperio; Michael P Keane; Douglas Arenberg; CL Addison; Jan Erik Ehlert; Marie D Burdick; Robert M Strieter
CXC chemokines in angiogenesis.
Journal of leukocyte biology 2000;68(1):1-8.
2000: John A Belperio; Marie D Burdick; Michael P Keane; Ying Ying Xue; Joseph P Lynch; B L Daugherty; Steven Kunkel; Robert M Strieter
The role of the CC chemokine, RANTES, in acute lung allograft rejection.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):461-72.
2000: Douglas Arenberg; Michael P Keane; Bruno DiGiovine; Steven Kunkel; SR Strom; Marie D Burdick; Mark D Iannettoni; Robert M Strieter
Macrophage infiltration in human non-small-cell lung cancer: the role of CC chemokines.
Cancer immunology, immunotherapy : CII 2000;49(2):63-70.
2000: Michael P Keane; Joseph P Lynch
Pleuropulmonary manifestations of systemic lupus erythematosus.
Thorax 2000;55(2):159-66.
1999: Michael P Keane; John A Belperio; Douglas Arenberg; Marie D Burdick; Zhaohui Xu; Ying Ying Xue; Robert M Strieter
IFN-gamma-inducible protein-10 attenuates bleomycin-induced pulmonary fibrosis via inhibition of angiogenesis.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5686-92.
1999: Robert M Strieter; Steven Kunkel; Michael P Keane; Theodore J Standiford
Chemokines in lung injury: Thomas A. Neff Lecture.
Chest 1999;116(1 Suppl):103S-110S.
1999: Michael P Keane; Carol A Wilke; Marie D Burdick; Susan B Morris; MC Glass; Robert M Strieter
CXC chemokines regulate angiogenic activity in acute lung injury.
Chest 1999;116(1 Suppl):93S-94S.
1999: Michael P Keane; John A Belperio; Thomas A Moore; Bethany B Moore; Douglas Arenberg; RE Smith; Marie D Burdick; Steven Kunkel; Robert M Strieter
Neutralization of the CXC chemokine, macrophage inflammatory protein-2, attenuates bleomycin-induced pulmonary fibrosis.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(9):5511-8.
1999: Michael P Keane; Robert M Strieter
The role of CXC chemokines in the regulation of angiogenesis.
Chemical immunology 1999;72():86-101.
1998: Bethany B Moore; Douglas Arenberg; CL Addison; Michael P Keane; Robert M Strieter
Tumor angiogenesis is regulated by CXC chemokines.
The Journal of laboratory and clinical medicine 1998;132(2):97-103.
1998: Douglas Arenberg; Michael P Keane; Bruno DiGiovine; Steven Kunkel; Susan B Morris; Ying Ying Xue; Marie D Burdick; MC Glass; Mark D Iannettoni; Robert M Strieter
Epithelial-neutrophil activating peptide (ENA-78) is an important angiogenic factor in non-small cell lung cancer.
The Journal of clinical investigation 1998;102(3):465-72.
1998: Michael P Keane; Douglas Arenberg; Bethany B Moore; CL Addison; Robert M Strieter
CXC chemokines and angiogenesis/angiostasis.
Proceedings of the Association of American Physicians 1998;110(4):288-96.
1998: Bethany B Moore; Michael P Keane; CL Addison; Douglas Arenberg; Robert M Strieter
CXC chemokine modulation of angiogenesis: the importance of balance between angiogenic and angiostatic members of the family.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 1998;46(4):113-20.
1998: Bethany B Moore; Douglas Arenberg; CL Addison; Michael P Keane; Peter J Polverini; Robert M Strieter
CXC chemokines mechanism of action in regulating tumor angiogenesis.
Angiogenesis 1998;2(2):123-34.
1997: Michael P Keane; Douglas Arenberg; Joseph P Lynch; R I Whyte; Mark D Iannettoni; Marie D Burdick; Carol A Wilke; Susan B Morris; MC Glass; Bruno DiGiovine; Steven Kunkel; Robert M Strieter
The CXC chemokines, IL-8 and IP-10, regulate angiogenic activity in idiopathic pulmonary fibrosis.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(3):1437-43.
1997: Michael P Keane; JF Meaney; Ella Annabelle Kazerooni; R I Whyte; Andrew Flint; Fernando J Martinez
Accessory cardiac bronchus presenting with haemoptysis.
Thorax 1997;52(5):490-1.