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John Kearney

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Kazuhito Honjo; Shozo Izui; Dewitt M Jones; John F Kearney; Yoshiki Kubagawa; Hiroshi Ohno; Zilu Zhu; Brian Dizon; Hiromi Kubagawa
Altered Ig levels and antibody responses in mice deficient for the Fc receptor for IgM (FcμR).
Nicholas W Kin; Emily K Stefanov; Brian L P Dizon; John F Kearney
Antibodies generated against conserved antigens expressed by bacteria and allergen-bearing fungi suppress airway disease.
Nicholas W Kin; Emily K Stefanov; Yao Chen; Richard L Gallo; John F Kearney
Cathelin-related antimicrobial peptide differentially regulates T- and B-cell function.

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All Publications

2012: Kazuhito Honjo; Shozo Izui; Dewitt M Jones; John F Kearney; Yoshiki Kubagawa; Hiroshi Ohno; Zilu Zhu; Brian Dizon; Hiromi Kubagawa
Altered Ig levels and antibody responses in mice deficient for the Fc receptor for IgM (FcμR).
Proceedings of the National Academy of Sciences of the United States of America 2012;109(39):15882-7.
2012: Nicholas W Kin; Emily K Stefanov; Brian L P Dizon; John F Kearney
Antibodies generated against conserved antigens expressed by bacteria and allergen-bearing fungi suppress airway disease.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(5):2246-56.
2011: Nicholas W Kin; Emily K Stefanov; Yao Chen; Richard L Gallo; John F Kearney
Cathelin-related antimicrobial peptide differentially regulates T- and B-cell function.
European journal of immunology 2011;41(10):3006-16.
2009: Claudia R Oliva; Charles L Turnbough; John F Kearney
CD14-Mac-1 interactions in Bacillus anthracis spore internalization by macrophages.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(33):13957-62.
2008: Mark W Lisanby; Melissa K Swiecki; Brian L P Dizon; Kathryn J Pflughoeft; Theresa Koehler; John F Kearney
Cathelicidin administration protects mice from Bacillus anthracis spore challenge.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4989-5000.
2008: Nicholas W Kin; Dianna M Crawford; Jiabin Liu; timothy wayne behrens; John F Kearney
DNA microarray gene expression profile of marginal zone versus follicular B cells and idiotype positive marginal zone B cells before and after immunization with Streptococcus pneumoniae.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(10):6663-74.
2008: John F Kearney
B cell subpopulations and secondary lymphoid organ architecture.
Seminars in immunology 2008;20(1):1-3.
2008: Claudia R Oliva; Melissa K Swiecki; Corinne E Griguer; Mark W Lisanby; Daniel C Bullard; Charles L Turnbough; John F Kearney
The integrin Mac-1 (CR3) mediates internalization and directs Bacillus anthracis spores into professional phagocytes.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(4):1261-6.
2008: Woong-Jai Won; Martin F Bachmann; John F Kearney
CD36 is differentially expressed on B cell subsets during development and in responses to antigen.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):230-7.
2007: Christopher T Steichen; John F Kearney; Charles L Turnbough
Non-uniform assembly of the Bacillus anthracis exosporium and a bottle cap model for spore germination and outgrowth.
Molecular microbiology 2007;64(2):359-67.
2006: Woong-Jai Won; Jeremy B Foote; Mary Odom; Jicun Pan; John F Kearney; Randall S Davis
Fc receptor homolog 3 is a novel immunoregulatory marker of marginal zone and B1 B cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):6815-23.
2006: Jeremy A Boydston; Ling Yue; John F Kearney; Charles L Turnbough
The ExsY protein is required for complete formation of the exosporium of Bacillus anthracis.
Journal of bacteriology 2006;188(21):7440-8.
2006: Melissa K Swiecki; Mark W Lisanby; Fengyu Shu; Charles L Turnbough; John F Kearney
Monoclonal antibodies for Bacillus anthracis spore detection and functional analyses of spore germination and outgrowth.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(10):6076-84.
2005: Christopher T Steichen; John F Kearney; Charles L Turnbough
Characterization of the exosporium basal layer protein BxpB of Bacillus anthracis.
Journal of bacteriology 2005;187(17):5868-76.
2005: Thiago Lopes-Carvalho; Jeremy Foote; John F Kearney
Marginal zone B cells in lymphocyte activation and regulation.
Current opinion in immunology 2005;17(3):244-50.
2005: John F Kearney
Innate-like B cells.
Springer seminars in immunopathology 2005;26(4):377-83.
2005: To-Ha Thai; John F Kearney
Isoforms of terminal deoxynucleotidyltransferase: developmental aspects and function.
Advances in immunology 2005;86():113-36.
2005: Thiago Lopes-Carvalho; John F Kearney
Marginal zone B cell physiology and disease.
Current directions in autoimmunity 2005;8():91-123.
2004: To-Ha Thai; John F Kearney
Distinct and opposite activities of human terminal deoxynucleotidyltransferase splice variants.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):4009-19.
2004: Thiago Lopes-Carvalho; John F Kearney
Development and selection of marginal zone B cells.
Immunological reviews 2004;197():192-205.
2004: Kalaya Attanavanich; John F Kearney
Marginal zone, but not follicular B cells, are potent activators of naive CD4 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):803-11.
2003: Jordan Knurr; Orsolya Benedek; Jennifer Heslop; Robert B Vinson; Jeremy A Boydston; Joanne McAndrew; John F Kearney; Charles L Turnbough
Peptide ligands that bind selectively to spores of Bacillus subtilis and closely related species.
Applied and environmental microbiology 2003;69(11):6841-7.
2003: Alexander Szalai; Casey T Weaver; Mark A McCrory; Frederik W van Ginkel; Rachael M Reiman; John F Kearney; Tony N Marion; John E Volanakis
Delayed lupus onset in (NZB x NZW)F1 mice expressing a human C-reactive protein transgene.
Arthritis and rheumatism 2003;48(6):1602-11.
2003: Christopher T Steichen; Ping Chen; John F Kearney; Charles L Turnbough
Identification of the immunodominant protein and other proteins of the Bacillus anthracis exosporium.
Journal of bacteriology 2003;185(6):1903-10.
2002: Fengyu Shu; Bernhard Holzmann; Frank Seibold; David Erle; John F Kearney
Activated alpha4 integrins are preferentially expressed on immature thymocytes and activated T cells.
Developmental immunology 2002;9(2):73-84.
2002: Woong-Jai Won; John F Kearney
CD9 is a unique marker for marginal zone B cells, B1 cells, and plasma cells in mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(11):5605-11.
2002: Flavius Martin; John F Kearney
Marginal-zone B cells.
Nature reviews. Immunology 2002;2(5):323-35.
2002: To-Ha Thai; Mary M Purugganan; David B Roth; John F Kearney
Distinct and opposite diversifying activities of terminal transferase splice variants.
Nature immunology 2002;3(5):457-62.
2001: Albert Bendelac; M Bonneville; John F Kearney
Autoreactivity by design: innate B and T lymphocytes.
Nature reviews. Immunology 2001;1(3):177-86.
2001: Flavius Martin; Alyce M. Oliver; John F Kearney
Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens.
Immunity 2001;14(5):617-29.
2001: Mary M Purugganan; S Shah; John F Kearney; David B Roth
Ku80 is required for addition of N nucleotides to V(D)J recombination junctions by terminal deoxynucleotidyl transferase.
Nucleic acids research 2001;29(7):1638-46.
2001: Flavius Martin; John F Kearney
B1 cells: similarities and differences with other B cell subsets.
Current opinion in immunology 2001;13(2):195-201.
2001: Xiaoli Li; Flavius Martin; Alyce M. Oliver; John F Kearney; Robert H Carter
Antigen receptor proximal signaling in splenic B-2 cell subsets.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):3122-9.
2001: CL Benedict; S Gilfillan; John F Kearney
The long isoform of terminal deoxynucleotidyl transferase enters the nucleus and, rather than catalyzing nontemplated nucleotide addition, modulates the catalytic activity of the short isoform.
The Journal of experimental medicine 2001;193(1):89-99.
2000: CL Benedict; S Gilfillan; To-Ha Thai; John F Kearney
Terminal deoxynucleotidyl transferase and repertoire development.
Immunological reviews 2000;175():150-7.
2000: Flavius Martin; John F Kearney
B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory".
Immunological reviews 2000;175():70-9.
2000: John F Kearney
Immune recognition of OxLDL in atherosclerosis.
The Journal of clinical investigation 2000;105(12):1683-5.
2000: Flavius Martin; John F Kearney
Selection in the mature B cell repertoire.
Current topics in microbiology and immunology 2000;252():97-105.
2000: Flavius Martin; John F Kearney
Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk.
Immunity 2000;12(1):39-49.
2000: Alexander Szalai; Stanley B Digerness; Alok Agrawal; John F Kearney; R P Bucy; S Niwas; J Michael Kilpatrick; Yarlagadda S Babu; John E Volanakis
The Arthus reaction in rodents: species-specific requirement of complement.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):463-8.
1999: Frederik W van Ginkel; S M Wahl; John F Kearney; Mi-Na Kweon; Kohtaro Fujihashi; P D Burrows; Hiroshi Kiyono; Jerry R McGhee
Partial IgA-deficiency with increased Th2-type cytokines in TGF-beta 1 knockout mice.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(4):1951-7.
1999: Alyce M. Oliver; Flavius Martin; John F Kearney
IgMhighCD21high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7198-207.
1999: CL Benedict; John F Kearney
Increased junctional diversity in fetal B cells results in a loss of protective anti-phosphorylcholine antibodies in adult mice.
Immunity 1999;10(5):607-17.
1999: Alyce M. Oliver; JC Grimaldi; MC Howard; John F Kearney
Independently ligating CD38 and Fc gammaRIIB relays a dominant negative signal to B cells.
Hybridoma 1999;18(2):113-9.
1999: James F George; Y Matsuura; J A Byrne; E L Liu; Denise R Shaw; John F Kearney
A developmental bias in reading frame usage by human fetal thymic TCRBDJ transcripts is not present in genomic TCRBDJ rearrangements.
Developmental immunology 1999;7(1):9-15.
1999: Flavius Martin; John F Kearney
CD21high IgMhigh splenic B cells enriched in the marginal zone: distinct phenotypes and functions.
Current topics in microbiology and immunology 1999;246():45-50; discussion 51-2.
1998: Q Lin; I Taniuchi; Daisuke Kitamura; Jianhua Wang; John F Kearney; T Watanabe; Max D Cooper
T and B cell development in BP-1/6C3/aminopeptidase A-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(10):4681-7.
1998: Flavius Martin; Woong-Jai Won; John F Kearney
Generation of the germline peripheral B cell repertoire: VH81X-lambda B cells are unable to complete all developmental programs.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(8):3748-58.
1997: Alyce M. Oliver; Flavius Martin; G Larry Gartland; Robert H Carter; John F Kearney
Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses.
European journal of immunology 1997;27(9):2366-74.
1997: Flavius Martin; X Chen; John F Kearney
Development of VH81X transgene-bearing B cells in fetus and adult: sites for expansion and deletion in conventional and CD5/B1 cells.
International immunology 1997;9(4):493-505.
1997: Alyce M. Oliver; Flavius Martin; John F Kearney
Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(3):1108-15.
1997: John F Kearney; Woong-Jai Won; C Benedict; C Moratz; P Zimmer; Alyce M. Oliver; Flavius Martin; Fengyu Shu
B cell development in mice.
International reviews of immunology 1997;15(3-4):207-41.
1997: X Chen; Flavius Martin; Katherine Forbush; Roger M Perlmutter; John F Kearney
Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone.
International immunology 1997;9(1):27-41.
1996: X Chen; John F Kearney
Generation and function of natural self-reactive B lymphocytes.
Seminars in immunology 1996;8(1):19-27.
1995: Flavius Martin; X Chen; F Shu; John F Kearney
Development of the mouse B-cell repertoire.
Annals of the New York Academy of Sciences 1995;764():207-21.
1995: D Young; John F Kearney
Sequence analysis and antigen binding characteristics of Ig SCID Ig+ mice.
International immunology 1995;7(5):807-19.
1995: Agnès Lehuen; L Beaudoin; M Bernard; John F Kearney; Jean-François Bach; Renato C Monteiro
T cell activation through Thy-1 is associated with the expression of a surface protein (p100) on a subset of CD4 cells.
International immunology 1995;7(4):607-16.
1995: X Chen; Y Matsuura; John F Kearney
CD5 transgenic mice.
Current topics in microbiology and immunology 1995;194():209-17.
1995: Ken Beagley; CA Black; S DiFabio; Jerry R McGhee; John F Kearney; John H Eldridge
Do CD5 B cells respond to oral antigens?
Advances in experimental medicine and biology 1995;371B():1439-44.
1994: A M Hamilton; Agnès Lehuen; John F Kearney
Immunofluorescence analysis of B-1 cell ontogeny in the mouse.
International immunology 1994;6(3):355-61.
1994: A M Hamilton; John F Kearney
Effects of IgM allotype suppression on serum IgM levels, B-1 and B-2 cells, and antibody responses in allotype heterozygous F1 mice.
Developmental immunology 1994;4(1):27-41.
1992: Agnès Lehuen; Joachim Bartels; John F Kearney
Characterization, specificity, and IgV gene usage of anti-lymphocyte monoclonal antibodies from perinatal mice.
International immunology 1992;4(10):1073-84.
1992: Agnès Lehuen; Renato C Monteiro; John F Kearney
Identification of a surface protein (p100) associated with two glycosyl-phosphatidylinositol-linked molecules (Thy-1 and ThB) by natural anti-lymphocyte autoantibodies.
European journal of immunology 1992;22(9):2373-80.
1992: M Elliott; John F Kearney
Idiotypic regulation of development of the B-cell repertoire.
Annals of the New York Academy of Sciences 1992;651():336-45.
1992: A M Hamilton; John F Kearney
Effect of a VH81X-expressing IgM antibody on early B-cell development.
Annals of the New York Academy of Sciences 1992;651():160-1.
1992: Joachim Bartels; M Elliott; John F Kearney
Perinatally derived antiidiotypic antibodies from the antipolyfructosan immune response. Molecular analysis of idiotype regulation.
Annals of the New York Academy of Sciences 1992;651():316-8.
1992: N Solvason; X Chen; F Shu; John F Kearney
The fetal omentum in mice and humans. A site enriched for precursors of CD5 B cells early in development.
Annals of the New York Academy of Sciences 1992;651():10-20.
1992: N Solvason; John F Kearney
The human fetal omentum: a site of B cell generation.
The Journal of experimental medicine 1992;175(2):397-404.
1992: John F Kearney
Early B-cell repertoires.
Current topics in microbiology and immunology 1992;182():81-4.
1992: John F Kearney; Joachim Bartels; A M Hamilton; Agnès Lehuen; N Solvason; M Vakil
Development and function of the early B cell repertoire.
International reviews of immunology 1992;8(2-3):247-57.
1991: N Solvason; Agnès Lehuen; John F Kearney
An embryonic source of Ly1 but not conventional B cells.
International immunology 1991;3(6):543-50.
1991: M Vakil; David E Briles; John F Kearney
Antigen-independent selection of T15 idiotype during B-cell ontogeny in mice.
Developmental immunology 1991;1(3):203-12.
1991: M Vakil; John F Kearney
Functional relationship between T15 and J558 idiotypes in BALB/c mice.
Developmental immunology 1991;1(3):213-24.
1990: J Ma; John F Kearney; L M Hendershot
Association of transport-defective light chains with immunoglobulin heavy chain binding protein.
Molecular immunology 1990;27(7):623-30.
1990: John F Kearney; N Solvason; A Bloem; M Vakil
Idiotypes and B cell development.
Chemical immunology 1990;48():1-13.
1989: John F Kearney; M Vakil; N Solvason
The role of idiotypic interactions and B-cell subsets in development of the B-cell repertoire.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 1():203-7.
1988: L M Hendershot; John F Kearney
A role for human heavy chain binding protein in the developmental regulation of immunoglobin transport.
Molecular immunology 1988;25(6):585-95.
1988: M Vakil; John F Kearney
Regulatory influences of neonatal multispecific antibodies on the developing B cell repertoire.
International reviews of immunology 1988;3(1-2):117-31.
1987: John F Kearney; M Vakil; Donard S Dwyer
Idiotypes and autoimmunity.
Ciba Foundation symposium 1987;129():109-22.
1987: Donard S Dwyer; M Vakil; Ronald J Bradley; Shin J Oh; John F Kearney
A possible cause of myasthenia gravis: idiotypic networks involving bacterial antigens.
Annals of the New York Academy of Sciences 1987;505():461-71.
1986: Donard S Dwyer; M Vakil; John F Kearney
Idiotypic network connectivity and a possible cause of myasthenia gravis.
The Journal of experimental medicine 1986;164(4):1310-8.
1983: Donard S Dwyer; Ronald J Bradley; C K Urquhart; John F Kearney
An enzyme-linked immunoabsorbent assay for measuring antibodies against muscle acetylcholine receptor.
Journal of immunological methods 1983;57(1-3):111-9.
1983: Donard S Dwyer; Ronald J Bradley; C K Urquhart; John F Kearney
Naturally occurring anti-idiotypic antibodies in myasthenia gravis patients.
Nature 1983;301(5901):611-4.
1981: Donard S Dwyer; John F Kearney; Ronald J Bradley; G E Kemp; Shin J Oh
Interaction of human antibody and murine monoclonal antibody with muscle acetylcholine receptor.
Annals of the New York Academy of Sciences 1981;377():143-57.