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Martin Keck

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Publications

TOP 3
Nicola Toschi; Tobias Welt; Martin E Keck; Maria Guerrisi
Quantifying uncertainty in Transcranial Magnetic Stimulation - A high resolution simulation study in ICBM space.
Carsten Hohoff; Emma L Mullings; Susan V Heatherley; Christine M Freitag; Lisa C Neumann; Katharina Domschke; Petra Krakowitzky; Matthias Rothermundt; Martin E Keck; Erhardt Angelika; Paul G Unschuld; Christian Jacob; Jürgen Fritze; Borwin Bandelow; Wolfgang Maier; Florian Holsboer; Peter J Rogers; Jürgen Deckert
Adenosine A(2A) receptor gene: evidence for association of risk variants with panic disorder and anxious personality.
Christoph K Thoeringer; Erhardt Angelika; Inge Sillaber; M B Mueller; frauke ohl; Florian Holsboer; Martin E Keck
Long-term anxiolytic and antidepressant-like behavioural effects of tiagabine, a selective GABA transporter-1 (GAT-1) inhibitor, coincide with a decrease in HPA system activity in C57BL/6 mice.

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All Publications

2012: Nicola Toschi; Tobias Welt; Martin E Keck; Maria Guerrisi
Quantifying uncertainty in Transcranial Magnetic Stimulation - A high resolution simulation study in ICBM space.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2012;2012():1218-21.
2010: Carsten Hohoff; Emma L Mullings; Susan V Heatherley; Christine M Freitag; Lisa C Neumann; Katharina Domschke; Petra Krakowitzky; Matthias Rothermundt; Martin E Keck; Erhardt Angelika; Paul G Unschuld; Christian Jacob; Jürgen Fritze; Borwin Bandelow; Wolfgang Maier; Florian Holsboer; Peter J Rogers; Jürgen Deckert
Adenosine A(2A) receptor gene: evidence for association of risk variants with panic disorder and anxious personality.
Journal of psychiatric research 2010;44(14):930-7.
2010: Christoph K Thoeringer; Erhardt Angelika; Inge Sillaber; M B Mueller; frauke ohl; Florian Holsboer; Martin E Keck
Long-term anxiolytic and antidepressant-like behavioural effects of tiagabine, a selective GABA transporter-1 (GAT-1) inhibitor, coincide with a decrease in HPA system activity in C57BL/6 mice.
Journal of psychopharmacology (Oxford, England) 2010;24(5):733-43.
2009: Christoph K Thoeringer; S Ripke; Paul G Unschuld; Susanne Lucae; Marcus Ising; Thomas Bettecken; Manfred Uhr; Martin E Keck; B Mueller-Myhsok; Florian Holsboer; Elisabeth B Binder; Erhardt Angelika
The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders.
Journal of neural transmission (Vienna, Austria : 1996) 2009;116(6):649-57.
2008: Martin E Keck; Nikola Kern; Erhardt Angelika; Paul G Unschuld; Marcus Ising; Daria Salyakina; Marianne B Müller; Carolin C Knorr; Roselind Lieb; Christa Hohoff; Petra Krakowitzky; Wolfgang Maier; Borwin Bandelow; Jürgen Fritze; Jürgen Deckert; Florian Holsboer; Bertram Müller-Myhsok; Elisabeth B Binder
Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(7):1196-204.
2008: Erhardt Angelika; Susanne Lucae; Nikola Kern; Paul G Unschuld; Marcus Ising; Roselind Lieb; Manfred Uhr; Carsten Hohoff; Jürgen Deckert; B Bandelow; Wolfgang Maier; Elisabeth B Binder; Bertram Müller-Myhsok; Martin E Keck; Florian Holsboer
Association of polymorphisms in the angiotensin-converting enzyme gene with syndromal panic attacks.
Molecular psychiatry 2008;13(3):242-3.
2008: Paul G Unschuld; Marcus Ising; Erhardt Angelika; Susanne Lucae; Martin Kohli; Stefan Kloiber; Daria Salyakina; Christoph K Thoeringer; Nikola Kern; Roselind Lieb; Manfred Uhr; Elisabeth B Binder; Bertram Müller-Myhsok; Florian Holsboer; Martin E Keck
Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder.
Journal of affective disorders 2008;105(1-3):177-84.
2007: Christoph K Thoeringer; Elisabeth B Binder; Daria Salyakina; Erhardt Angelika; Marcus Ising; Paul G Unschuld; Nikola Kern; Susanne Lucae; Tanja M Brueckl; Marianne B Mueller; Brigitte Fuchs; Benno Pütz; Roselind Lieb; Manfred Uhr; Florian Holsboer; Bertram Mueller-Myhsok; Martin E Keck
Association of a Met88Val diazepam binding inhibitor (DBI) gene polymorphism and anxiety disorders with panic attacks.
Journal of psychiatric research 2007;41(7):579-84.
2007: Erhardt Angelika; Susanne Lucae; Paul G Unschuld; Marcus Ising; Nikola Kern; Daria Salyakina; Roselind Lieb; Manfred Uhr; Elisabeth B Binder; Martin E Keck; Bertram Müller-Myhsok; Florian Holsboer
Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders.
Journal of affective disorders 2007;101(1-3):159-68.
2007: Christoph K Thoeringer; Inge Sillaber; Angelika Roedel; Erhardt Angelika; Marianne B Mueller; frauke ohl; Florian Holsboer; Martin E Keck
The temporal dynamics of intrahippocampal corticosterone in response to stress-related stimuli with different emotional and physical load: an in vivo microdialysis study in C57BL/6 and DBA/2 inbred mice.
Psychoneuroendocrinology 2007;32(6):746-57.
2007: Paul G Unschuld; Marcus Ising; Erhardt Angelika; Susanne Lucae; Stefan Kloiber; Martin Kohli; Daria Salyakina; Tobias Welt; Nikola Kern; Roselind Lieb; Manfred Uhr; Elisabeth B Binder; Bertram Müller-Myhsok; Florian Holsboer; Martin E Keck
Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(4):424-9.
2006: Tobias Welt; Mario Engelmann; Ulrich Renner; Erhardt Angelika; Marianne B Müller; Rainer Landgraf; Florian Holsboer; Martin E Keck
Temazepam triggers the release of vasopressin into the rat hypothalamic paraventricular nucleus: novel insight into benzodiazepine action on hypothalamic-pituitary-adrenocortical system activity during stress.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(12):2573-9.
2006: Erhardt Angelika; Marcus Ising; Paul G Unschuld; Nikola Kern; Susanne Lucae; Benno Pütz; Manfred Uhr; Elisabeth B Binder; Florian Holsboer; Martin E Keck
Regulation of the hypothalamic-pituitary-adrenocortical system in patients with panic disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(11):2515-22.
2006: Ngoc Khoi Nguyen; Martin E Keck; Alfred Hetzenauer; Christoph K Thoeringer; Wolfgang Wurst; Jan M Deussing; Florian Holsboer; Marianne B Müller; Nicolas Singewald
Conditional CRF receptor 1 knockout mice show altered neuronal activation pattern to mild anxiogenic challenge.
Psychopharmacology 2006;188(3):374-85.
2006: Dan Rujescu; Andreas Bender; Martin E Keck; Annette M Hartmann; frauke ohl; Hanna Raeder; Ina Giegling; Just Genius; Robert W McCarley; Hans-Jürgen Möller; Heinz Grunze
A pharmacological model for psychosis based on N-methyl-D-aspartate receptor hypofunction: molecular, cellular, functional and behavioral abnormalities.
Biological psychiatry 2006;59(8):721-9.
2005: Martin E Keck; Simone B Sartori; Tobias Welt; Marianne B Müller; frauke ohl; Florian Holsboer; Rainer Landgraf; Nicolas Singewald
Differences in serotonergic neurotransmission between rats displaying high or low anxiety/depression-like behaviour: effects of chronic paroxetine treatment.
Journal of neurochemistry 2005;92(5):1170-9.
2005: Martin E Keck; A Ströhle
Challenge studies in anxiety disorders.
Handbook of experimental pharmacology 2005;(169):449-68.
2005: Martin E Keck; Marianne B Müller
Mutagenesis and knockout models: hypothalamic-pituitary-adrenocortical system.
Handbook of experimental pharmacology 2005;(169):113-41.
2005: Martin E Keck; frauke ohl; Florian Holsboer; Marianne B Müller
Listening to mutant mice: a spotlight on the role of CRF/CRF receptor systems in affective disorders.
Neuroscience and biobehavioral reviews 2005;29(4-5):867-89.
2004: Erhardt Angelika; Inge Sillaber; Tobias Welt; Marianne B Müller; Nicolas Singewald; Martin E Keck
Repetitive transcranial magnetic stimulation increases the release of dopamine in the nucleus accumbens shell of morphine-sensitized rats during abstinence.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(11):2074-80.
2004: Martin E Keck; Florian Holsboer; Marianne B Müller
Mouse mutants for the study of corticotropin-releasing hormone receptor function: development of novel treatment strategies for mood disorders.
Annals of the New York Academy of Sciences 2004;1018():445-57.
2004: Marianne B Müller; Manfred Uhr; Florian Holsboer; Martin E Keck
Hypothalamic-pituitary-adrenocortical system and mood disorders: highlights from mutant mice.
Neuroendocrinology 2004;79(1):1-12.
2004: Martin E Keck; Marianne B Müller; Elisabeth B Binder; Annette Sonntag; Florian Holsboer
Ziprasidone-related tardive dyskinesia.
The American journal of psychiatry 2004;161(1):175-6.
2003: frauke ohl; Martin E Keck
Behavioural screening in mutagenised mice--in search for novel animal models of psychiatric disorders.
European journal of pharmacology 2003;480(1-3):219-28.
2003: Marianne B Müller; Martin E Keck; Elisabeth B Binder; Adelheid E Kresse; Thomas P Hagemeyer; Rainer Landgraf; Florian Holsboer; Manfred Uhr
ABCB1 (MDR1)-type P-glycoproteins at the blood-brain barrier modulate the activity of the hypothalamic-pituitary-adrenocortical system: implications for affective disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(11):1991-9.
2003: Martin E Keck
[Repetitive transcranial magnetic stimulation (rTMS). Application to depression].
Medizinische Monatsschrift für Pharmazeuten 2003;26(7):227-31.
2003: Martin E Keck; Tobias Welt; Marianne B Müller; Manfred Uhr; frauke ohl; Alexandra Wigger; Nicola Toschi; Florian Holsboer; Rainer Landgraf
Reduction of hypothalamic vasopressinergic hyperdrive contributes to clinically relevant behavioral and neuroendocrine effects of chronic paroxetine treatment in a psychopathological rat model.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(2):235-43.
2003: Martin E Keck
rTMS as treatment strategy in psychiatric disorders--neurobiological concepts.
Supplements to Clinical neurophysiology 2003;56():100-16.
2003: Martin E Keck; Tobias Welt; Marianne B Müller; Rainer Landgraf; Florian Holsboer
The high-affinity non-peptide CRH1 receptor antagonist R121919 attenuates stress-induced alterations in plasma oxytocin, prolactin, and testosterone secretion in rats.
Pharmacopsychiatry 2003;36(1):27-31.
2002: Boldizsár Czéh; Tobias Welt; Anja K Fischer; Erhardt Angelika; Wolfram Schmitt; Marianne B Müller; Nicola Toschi; Eberhard Fuchs; Martin E Keck
Chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation: effects on stress hormone levels and adult hippocampal neurogenesis.
Biological psychiatry 2002;52(11):1057-65.
2002: Frank Padberg; Peter Zwanzger; Martin E Keck; Norbert Kathmann; Patrick Mikhaiel; Robin Ella; Philipp Rupprecht; Heike Thoma; Harald Hampel; Nicola Toschi; Hans-Jürgen Möller
Repetitive transcranial magnetic stimulation (rTMS) in major depression: relation between efficacy and stimulation intensity.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;27(4):638-45.
2002: Jürgen Brunner; Martin E Keck; Rainer Landgraf; Manfred Uhr; Christian Namendorf; Thomas Bronisch
Vasopressin in CSF and plasma in depressed suicide attempters: preliminary results.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2002;12(5):489-94.
2002: Martin E Keck; Tobias Welt; Marianne B Müller; Erhardt Angelika; frauke ohl; Nicola Toschi; Florian Holsboer; Inge Sillaber
Repetitive transcranial magnetic stimulation increases the release of dopamine in the mesolimbic and mesostriatal system.
Neuropharmacology 2002;43(1):101-9.
2002: Marianne Müller; Florian Holsboer; Martin E Keck
Genetic modification of corticosteroid receptor signalling: novel insights into pathophysiology and treatment strategies of human affective disorders.
Neuropeptides 2002;36(2-3):117-31.
2002: Peter Zwanzger; Robin Ella; Martin E Keck; Rainer Rupprecht; Frank Padberg
Occurrence of delusions during repetitive transcranial magnetic stimulation (rTMS) in major depression.
Biological psychiatry 2002;51(7):602-3.
2002: Marianne B Müller; Martin E Keck
Genetically engineered mice for studies of stress-related clinical conditions.
Journal of psychiatric research 2002;36(2):53-76.
2002: Martin E Keck; Alexandra Wigger; Tobias Welt; Marianne B Müller; Angela Gesing; Johannes M H M Reul; Florian Holsboer; Rainer Landgraf; Inga D Neumann
Vasopressin mediates the response of the combined dexamethasone/CRH test in hyper-anxious rats: implications for pathogenesis of affective disorders.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;26(1):94-105.
2001: Marianne B Müller; J Preil; Ulrich Renner; Stephan Zimmermann; Adelheid E Kresse; Günter K Stalla; Martin E Keck; Florian Holsboer; Wolfgang Wurst
Expression of CRHR1 and CRHR2 in mouse pituitary and adrenal gland: implications for HPA system regulation.
Endocrinology 2001;142(9):4150-3.
2001: Anke Post; Martin E Keck
Transcranial magnetic stimulation as a therapeutic tool in psychiatry: what do we know about the neurobiological mechanisms?
Journal of psychiatric research 2001;35(4):193-215.
2001: frauke ohl; Inge Sillaber; Elisabeth B Binder; Martin E Keck; Florian Holsboer
Differential analysis of behavior and diazepam-induced alterations in C57BL/6N and BALB/c mice using the modified hole board test.
Journal of psychiatric research 2001;35(3):147-54.
2001: Martin E Keck; Florian Holsboer
Hyperactivity of CRH neuronal circuits as a target for therapeutic interventions in affective disorders.
Peptides 2001;22(5):835-44.
2001: Martin E Keck; Tobias Welt; Anke Post; Marianne B Müller; Nicola Toschi; Alexandra Wigger; Rainer Landgraf; Florian Holsboer; Mario Engelmann
Neuroendocrine and behavioral effects of repetitive transcranial magnetic stimulation in a psychopathological animal model are suggestive of antidepressant-like effects.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;24(4):337-49.
2001: Martin E Keck; Tobias Welt; Alexandra Wigger; Ulrich Renner; Mario Engelmann; Florian Holsboer; Rainer Landgraf
The anxiolytic effect of the CRH(1) receptor antagonist R121919 depends on innate emotionality in rats.
The European journal of neuroscience 2001;13(2):373-80.
2000: Marianne B Müller; Rainer Landgraf; J Preil; Inge Sillaber; Adelheid E Kresse; Martin E Keck; Stephan Zimmermann; Florian Holsboer; Wolfgang Wurst
Selective activation of the hypothalamic vasopressinergic system in mice deficient for the corticotropin-releasing hormone receptor 1 is dependent on glucocorticoids.
Endocrinology 2000;141(11):4262-9.
2000: Martin E Keck; Inge Sillaber; Karl Ebner; Tobias Welt; Nicola Toschi; Stefan T Kaehler; Nicolas Singewald; Athineos Philippou; Gregor Elbel; Carsten T Wotjak; Florian Holsboer; Rainer Landgraf; Mario Engelmann
Acute transcranial magnetic stimulation of frontal brain regions selectively modulates the release of vasopressin, biogenic amines and amino acids in the rat brain.
The European journal of neuroscience 2000;12(10):3713-20.
2000: Marianne B Müller; Rainer Landgraf; Martin E Keck
Vasopressin, major depression, and hypothalamic-pituitary-adrenocortical desensitization.
Biological psychiatry 2000;48(4):330-3.
2000: Marianne B Müller; Nicola Toschi; Adelheid E Kresse; Anke Post; Martin E Keck
Long-term repetitive transcranial magnetic stimulation increases the expression of brain-derived neurotrophic factor and cholecystokinin mRNA, but not neuropeptide tyrosine mRNA in specific areas of rat brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;23(2):205-15.
2000: Bettina Hermann; R Landgraf; Martin E Keck; Alexandra Wigger; A Leslie Morrow; Andreas Ströhle; Florian Holsboer; Rainer Rupprecht
Pharmacological characterisation of cortical gamma-aminobutyric acid type A (GABAA) receptors in two Wistar rat lines selectively bred for high and low anxiety-related behaviour.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2000;1(3):137-43.
2000: Martin E Keck; Mario Engelmann; Marianne B Müller; Markus S H Henniger; Bettina Hermann; Rainer Rupprecht; Inga D Neumann; Nicola Toschi; Rainer Landgraf; Anke Post
Repetitive transcranial magnetic stimulation induces active coping strategies and attenuates the neuroendocrine stress response in rats.
Journal of psychiatric research 2000;34(4-5):265-76.
2000: Marianne B Müller; Martin E Keck; Stephan Zimmermann; Florian Holsboer; Wolfgang Wurst
Disruption of feeding behavior in CRH receptor 1-deficient mice is dependent on glucocorticoids.
Neuroreport 2000;11(9):1963-6.
2000: Martin E Keck; M Hatzinger; Carsten T Wotjak; Rainer Landgraf; Florian Holsboer; Inga D Neumann
Ageing alters intrahypothalamic release patterns of vasopressin and oxytocin in rats.
The European journal of neuroscience 2000;12(4):1487-94.
2000: M Hatzinger; Carsten T Wotjak; T Naruo; R Simchen; Martin E Keck; Rainer Landgraf; Florian Holsboer; Inga D Neumann
Endogenous vasopressin contributes to hypothalamic-pituitary-adrenocortical alterations in aged rats.
The Journal of endocrinology 2000;164(2):197-205.
1999: A Post; Marianne B Müller; Mario Engelmann; Martin E Keck
Repetitive transcranial magnetic stimulation in rats: evidence for a neuroprotective effect in vitro and in vivo.
The European journal of neuroscience 1999;11(9):3247-54.
1999: Alexandra Wigger; P Lörscher; I Oehler; Martin E Keck; T Naruo; Inga D Neumann
Nonresponsiveness of the rat hypothalamo-pituitary-adrenocortical axis to parturition-related events: inhibitory action of endogenous opioids.
Endocrinology 1999;140(6):2843-9.
1998: Inga Neumann; Alexandra Wigger; M Hatzinger; Martin E Keck
Pregnancy and aging. Two model systems with altered release patterns of oxytocin and vasopressin within the hypothalamus.
Advances in experimental medicine and biology 1998;449():179-81.