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Barbara Kee

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Wei Xu; Tiffany Carr; Stephanie McGregor; Kevin Ramirez; Mikael Sigvardsson; Barbara L Kee
E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment.
Kevin Ramirez; Mikael Sigvardsson; Christina Spaulding; Sasan Zandi; Katherine J Chandler; Barbara J Graves; Barbara L Kee
Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1.
Malay Mandal; Sarah E Powers; Elizabeth T Bartom; Aaron R Dinner; Keith M Hamel; Barbara L Kee; Mark Maienschein-Cline; Marcus R Clark
Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2.

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All Publications

2013: Wei Xu; Tiffany Carr; Stephanie McGregor; Kevin Ramirez; Mikael Sigvardsson; Barbara L Kee
E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment.
Blood 2013;121(9):1534-42.
2012: Kevin Ramirez; Mikael Sigvardsson; Christina Spaulding; Sasan Zandi; Katherine J Chandler; Barbara J Graves; Barbara L Kee
Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1.
Immunity 2012;36(6):921-32.
2011: Malay Mandal; Sarah E Powers; Elizabeth T Bartom; Aaron R Dinner; Keith M Hamel; Barbara L Kee; Mark Maienschein-Cline; Marcus R Clark
Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2.
Nature immunology 2011;12(12):1212-20.
2011: Barbara L Kee
A comprehensive transcriptional landscape of human hematopoiesis.
Cell stem cell 2011;8(2):122-4.
2010: Renée F de Pooter; Barbara L Kee
E proteins and the regulation of early lymphocyte development.
Immunological reviews 2010;238(1):93-109.
2010: Mihalis Verykokakis; Markus D Boos; Albert Bendelac; Barbara L Kee
SAP protein-dependent natural killer T-like cells regulate the development of CD8(+) T cells with innate lymphocyte characteristics.
Immunity 2010;33(2):203-15.
2010: Kevin Ramirez; Barbara L Kee
Multiple hats for natural killers.
Current opinion in immunology 2010;22(2):193-8.
2010: Mihalis Verykokakis; Markus D Boos; Albert Bendelac; Erin J Adams; Pablo Pereira; Barbara L Kee
Inhibitor of DNA binding 3 limits development of murine slam-associated adaptor protein-dependent "innate" gammadelta T cells.
PloS one 2010;5(2):e9303.
2009: Malay Mandal; Sarah E Powers; Kyoko Ochiai; Katia Georgopoulos; Barbara L Kee; Harinder Singh; Marcus R Clark
Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development.
Nature immunology 2009;10(10):1110-7.
2009: Jie Gao; Stephanie Graves; Ute Koch; Suqing Liu; Vladimir Jankovic; Silvia Buonamici; Abdeljabar El Andaloussi; Stephen D Nimer; Barbara L Kee; Russell Taichman; Freddy Radtke; Ioannis Aifantis
Hedgehog signaling is dispensable for adult hematopoietic stem cell function.
Cell stem cell 2009;4(6):548-58.
2009: Barbara L Kee; Sheila Dias
A s-myly route toward lymphoid differentiation.
Immunity 2009;30(4):474-6.
2009: Barbara L Kee
E and ID proteins branch out.
Nature reviews. Immunology 2009;9(3):175-84.
2008: Sheila Dias; Wei Xu; Stephanie McGregor; Barbara L Kee
Transcriptional regulation of lymphocyte development.
Current opinion in genetics & development 2008;18(5):441-8.
2008: Sheila Dias; Robert Månsson; Sandeep Gurbuxani; Mikael Sigvardsson; Barbara L Kee
E2A proteins promote development of lymphoid-primed multipotent progenitors.
Immunity 2008;29(2):217-27.
2008: Savita Bhalla; Christina Spaulding; Rachel L Brumbaugh; Derek E Zagort; ME Massari; Cornelis Murre; Barbara L Kee
differential roles for the E2A activation domains in B lymphocytes and macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(3):1694-703.
2008: Markus D Boos; Kevin Ramirez; Barbara L Kee
Extrinsic and intrinsic regulation of early natural killer cell development.
Immunologic research 2008;40(3):193-207.
2008: L L Molinero; Ping Zhou; Y Wang; Helena Harlin; Barbara L Kee; C Abraham; Maria-Luisa Alegre
Epidermal Langerhans cells promote skin allograft rejection in mice with NF-kappa B-impaired T cells.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(1):21-31.
2007: Christina Spaulding; Erica J Reschly; Derek E Zagort; Yumi Yashiro-ohtani; Levi J Beverly; Anthony John Capobianco; Warren S Pear; Barbara L Kee
Notch1 co-opts lymphoid enhancer factor 1 for survival of murine T-cell lymphomas.
Blood 2007;110(7):2650-8.
2007: Stephen L Nutt; Barbara L Kee
The transcriptional regulation of B cell lineage commitment.
Immunity 2007;26(6):715-25.
2007: Robert S Welner; Rosana Pelayo; Karla P Garrett; Xinrong Chen; S Scott Perry; Xiao-Hong Sun; Barbara L Kee; Paul W Kincade
Interferon-producing killer dendritic cells (IKDCs) arise via a unique differentiation pathway from primitive c-kitHiCD62L+ lymphoid progenitors.
Blood 2007;109(11):4825-931.
2007: Wei Xu; Barbara L Kee
Growth factor independent 1B (Gfi1b) is an E2A target gene that modulates Gata3 in T-cell lymphomas.
Blood 2007;109(10):4406-14.
2007: Markus D Boos; Yoshifumi Yokota; Gerard Eberl; Barbara L Kee
Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activity.
The Journal of experimental medicine 2007;204(5):1119-30.
2007: Tomas Vilimas; Joaquina Mascarenhas; Teresa Palomero; Malay Mandal; Silvia Buonamici; Fanyong Meng; Benjamín Thompson; Christina Spaulding; Sami Macaroun; Maria-Luisa Alegre; Barbara L Kee; Adolfo Ferrando; Lucio Miele; Ioannis Aifantis
Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.
Nature medicine 2007;13(1):70-7.
2006: Erica J Reschly; Christina Spaulding; Tomas Vilimas; W Vallen Graham; Rachel L Brumbaugh; Ioannis Aifantis; Warren S Pear; Barbara L Kee
Notch1 promotes survival of E2A-deficient T cell lymphomas through pre-T cell receptor-dependent and -independent mechanisms.
Blood 2006;107(10):4115-21.
2005: Monica L Friedrich; Ben G Wen; Gretchen Bain; Barbara L Kee; Carol D Katayama; Cornelis Murre; Stephen M Hedrick; Craig M Walsh
DRAK2, a lymphoid-enriched DAP kinase, regulates the TCR activation threshold during thymocyte selection.
International immunology 2005;17(11):1379-90.
2005: Barbara L Kee
Id3 induces growth arrest and caspase-2-dependent apoptosis in B lymphocyte progenitors.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4518-27.
2005: Stephanie A Nick McElhinny; Jody M Havener; Miguel Garcia-Diaz; Raquel Juárez; Katarzyna Bebenek; Barbara L Kee; Luis Blanco; Thomas A Kunkel; Dale A Ramsden
A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining.
Molecular cell 2005;19(3):357-66.
2005: Barbara A Osborne; Barbara L Kee
Lymphoid development: it's not 'all Greek to us' any more.
Nature immunology 2005;6(2):119-23.
2005: Barbara L Kee
Helix-loop-helix proteins in lymphocyte lineage determination.
Current topics in microbiology and immunology 2005;290():15-27.
2004: Christopher S Seet; Rachel L Brumbaugh; Barbara L Kee
Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A.
The Journal of experimental medicine 2004;199(12):1689-700.
2004: Eric J Perkins; Barbara L Kee; Dale A Ramsden
Histone 3 lysine 4 methylation during the pre-B to immature B-cell transition.
Nucleic acids research 2004;32(6):1942-7.
2002: Barbara L Kee; Gretchen Bain; Cornelis Murre
IL-7Ralpha and E47: independent pathways required for development of multipotent lymphoid progenitors.
The EMBO journal 2002;21(1-2):103-13.
2001: Barbara L Kee; Cornelis Murre
Transcription factor regulation of B lineage commitment.
Current opinion in immunology 2001;13(2):180-5.
2001: Barbara L Kee; Richard R Rivera; Cornelis Murre
Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-beta.
Nature immunology 2001;2(3):242-7.
2000: Barbara L Kee; Melanie W Quong; Cornelis Murre
E2A proteins: essential regulators at multiple stages of B-cell development.
Immunological reviews 2000;175():138-49.
1998: Barbara L Kee; Cornelis Murre
Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12.
The Journal of experimental medicine 1998;188(4):699-713.
1996: Barbara L Kee; Christopher J Paige
In vitro tracking of IL-7 responsiveness and gene expression during commitment of bipotent B-cell/macrophage progenitors.
Current biology : CB 1996;6(9):1159-69.
1996: Barbara L Kee; J Arias; Marc Montminy
Adaptor-mediated recruitment of RNA polymerase II to a signal-dependent activator.
The Journal of biological chemistry 1996;271(5):2373-5.
1995: A J Marshall; Barbara L Kee; Christopher J Paige; Gillian E Wu
Analysis of immunoglobulin gene rearrangement in fetal B-cell progenitors developing in vivo or in vitro.
Annals of the New York Academy of Sciences 1995;764():222-3.
1995: Barbara L Kee; Christopher J Paige
In-vitro models of B-lineage commitment.
Seminars in immunology 1995;7(3):143-54.
1995: Barbara L Kee; Christopher J Paige
Murine B cell development: commitment and progression from multipotential progenitors to mature B lymphocytes.
International review of cytology 1995;157():129-79.
1994: Barbara L Kee; A Cumano; Norman N Iscove; Christopher J Paige
Stromal cell independent growth of bipotent B cell--macrophage precursors from murine fetal liver.
International immunology 1994;6(3):401-7.
1994: A Cumano; Barbara L Kee; Dale A Ramsden; A Marshall; Christopher J Paige; Gillian E Wu
Development of B lymphocytes from lymphoid committed and uncommitted progenitors.
Immunological reviews 1994;137():5-33.
1992: Barbara L Kee; Christopher J Paige; Michelle Letarte
Characterization of murine CD10, an endopeptidase expressed on bone marrow adherent cells.
International immunology 1992;4(9):1041-7.
1991: Barbara L Kee; Harjit Dadi; R Tran-Paterson; E J Quackenbush; I L Andrulis; Michelle Letarte
CD10 and CD44 genes of leukemic cells and malignant cell lines show no evidence of transformation-related alterations.
Journal of cellular physiology 1991;148(3):414-20.