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Peter Keipert

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Chemicals & Drugs

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Peter E Keipert; Christina Olofsson; Robert M Winslow
Hemoglobin-based blood substitutes and risk of myocardial infarction and death.
Christina Olofsson; EB Nygårds; Sari Ponzer; Bengt Fagrell; Robert J Przybelski; Peter E Keipert; Nancy Winslow; Robert M Winslow
A randomized, single-blind, increasing dose safety trial of an oxygen-carrying plasma expander (Hemospan) administered to orthopaedic surgery patients with spinal anaesthesia.
Dirk Bruegger; Gregor I Kemming; Matthias Jacob; Franz Meisner; Christoph J Wojtczyk; Kristian B Packert; Peter E Keipert; N Simon Faithfull; Oliver Habler; Bernhard F Becker; Markus Rehm
Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions.

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All Publications

2008: Peter E Keipert; Christina Olofsson; Robert M Winslow
Hemoglobin-based blood substitutes and risk of myocardial infarction and death.
JAMA : the journal of the American Medical Association 2008;300(11):1295-6; author reply 1298-9.
2008: Christina Olofsson; EB Nygårds; Sari Ponzer; Bengt Fagrell; Robert J Przybelski; Peter E Keipert; Nancy Winslow; Robert M Winslow
A randomized, single-blind, increasing dose safety trial of an oxygen-carrying plasma expander (Hemospan) administered to orthopaedic surgery patients with spinal anaesthesia.
Transfusion medicine (Oxford, England) 2008;18(1):28-39.
2007: Dirk Bruegger; Gregor I Kemming; Matthias Jacob; Franz Meisner; Christoph J Wojtczyk; Kristian B Packert; Peter E Keipert; N Simon Faithfull; Oliver Habler; Bernhard F Becker; Markus Rehm
Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions.
Critical care (London, England) 2007;11(6):R130.
2006: Christina Olofsson; Torbjörn Ahl; Torsten Johansson; Sune Larsson; Per Nellgård; Sari Ponzer; Bengt Fagrell; Robert J Przybelski; Peter E Keipert; Nancy Winslow; Robert M Winslow
A multicenter clinical study of the safety and activity of maleimide-polyethylene glycol-modified Hemoglobin (Hemospan) in patients undergoing major orthopedic surgery.
Anesthesiology 2006;105(6):1153-63.
2005: Gregor I Kemming; Franz Meisner; Christoph J Wojtczyk; Kristian B Packert; Thomas Minor; Manfred Thiel; Jochen Tillmanns; Jens Meier; Daniel Bottino; Peter E Keipert; Simon Faithfull; Oliver Habler
Oxygent as a top load to colloid and hyperoxia is more effective in resuscitation from hemorrhagic shock than colloid and hyperoxia alone.
Shock (Augusta, Ga.) 2005;24(3):245-54.
2003: Peter E Keipert
Oxygen therapeutics ("blood substitutes") where are they, and what can we expect?
Advances in experimental medicine and biology 2003;540():207-13.
2002: Donat R Spahn; Klaus F Waschke; Thomas Standl; Johann Motsch; Léone Van Huynegem; Martin Welte; Hans Gombotz; Pierre Coriat; Lev Verkh; Simon Faithfull; Peter E Keipert
Use of perflubron emulsion to decrease allogeneic blood transfusion in high-blood-loss non-cardiac surgery: results of a European phase 3 study.
Anesthesiology 2002;97(6):1338-49.
2002: Steven E Hill; Bruce J Leone; N Simon Faithfull; Kathy E Flaim; Peter E Keipert; Mark F Newman
Perflubron emulsion (AF0144) augments harvesting of autologous blood: a phase II study in cardiac surgery.
Journal of cardiothoracic and vascular anesthesia 2002;16(5):555-60.
2000: Dirk Nolte; S Pickelmann; M Lang; Peter E Keipert; Konrad Messmer
Compatibility of different colloid plasma expanders with perflubron emulsion: an intravital microscopic study in the hamster.
Anesthesiology 2000;93(5):1261-70.
2000: Robert J Noveck; E J Shannon; P T Leese; J S Shorr; Kathy E Flaim; Peter E Keipert; C M Woods
Randomized safety studies of intravenous perflubron emulsion. II. Effects on immune function in healthy volunteers.
Anesthesia and analgesia 2000;91(4):812-22.
2000: P T Leese; Robert J Noveck; J S Shorr; C M Woods; Kathy E Flaim; Peter E Keipert
Randomized safety studies of intravenous perflubron emulsion. I. Effects on coagulation function in healthy volunteers.
Anesthesia and analgesia 2000;91(4):804-11.
1999: Donat R Spahn; R van Brempt; Gregor Theilmeier; J P Reibold; Martin Welte; H Heinzerling; K M Birck; Peter E Keipert; Konrad Messmer; H Heinzerling; K M Birck; P E Keipert; K Messmer
Perflubron emulsion delays blood transfusions in orthopedic surgery. European Perflubron Emulsion Study Group.
Anesthesiology 1999;91(5):1195-208.
1999: Jörg Hutter; Oliver Habler; Martin Kleen; M Tiede; Armin Podtschaske; Gregor I Kemming; Carlos Corso; SANJAY BATRA; Peter E Keipert; Simon Faithfull; Konrad Messmer
Effect of acute normovolemic hemodilution on distribution of blood flow and tissue oxygenation in dog skeletal muscle.
Journal of applied physiology (Bethesda, Md. : 1985) 1999;86(3):860-6.
1998: Oliver Habler; Martin Kleen; Jörg Hutter; Armin Podtschaske; M Tiede; Gregor I Kemming; Martin Welte; Carlos Corso; SANJAY BATRA; Peter E Keipert; Simon Faithfull; Konrad Messmer
IV perflubron emulsion versus autologous transfusion in severe normovolemic anemia: effects on left ventricular perfusion and function.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1998;197(6):301-18.
1998: Martin Kleen; Oliver Habler; Jörg Hutter; Armin Podtschaske; M Tiede; Gregor I Kemming; Martin Welte; Peter E Keipert; SANJAY BATRA; N Simon Faithfull; Carlos Corso; Konrad Messmer
Normovolaemic haemodilution and hyperoxia have no effect on fractal dimension of regional myocardial perfusion in dogs.
Acta physiologica Scandinavica 1998;162(4):439-46.
1998: Oliver Habler; Martin Kleen; JW Hutter; Armin Podtschaske; M Tiede; Gregor I Kemming; Martin Welte; Carlos Corso; SANJAY BATRA; Peter E Keipert; N Simon Faithfull; Konrad Messmer
Hemodilution and intravenous perflubron emulsion as an alternative to blood transfusion: effects on tissue oxygenation during profound hemodilution in anesthetized dogs.
Transfusion 1998;38(2):145-55.
1998: Oliver Habler; Martin Kleen; JW Hutter; Armin Podtschaske; M Tiede; Gregor I Kemming; Martin Welte; Carlos Corso; SANJAY BATRA; Peter E Keipert; N Simon Faithfull; Konrad Messmer
Effects of hyperoxic ventilation on hemodilution-induced changes in anesthetized dogs.
Transfusion 1998;38(2):135-44.
1998: Martin Kleen; Oliver Habler; Jörg Hutter; Gregor I Kemming; Armin Podtschaske; M Tiede; Martin Welte; Peter E Keipert; SANJAY BATRA; N Simon Faithfull; Carlos Corso; Bernhard Zwissler; Konrad Messmer
Hemodilution and hyperoxia locally change distribution of regional pulmonary perfusion in dogs.
The American journal of physiology 1998;274(2 Pt 2):H520-8.
1997: Oliver Habler; Martin Kleen; Jörg Hutter; Armin Podtschaske; M Tiede; Gregor I Kemming; Carlos Corso; SANJAY BATRA; Peter E Keipert; Simon Faithfull; Konrad Messmer
Effects of hemodilution on splanchnic perfusion and hepatorenal function. II. Renal perfusion and hepatorenal function.
European journal of medical research 1997;2(10):419-24.
1997: Martin Kleen; Oliver Habler; Jörg Hutter; Armin Podtschaske; M Tiede; Gregor I Kemming; Carlos Corso; SANJAY BATRA; Peter E Keipert; Simon Faithfull; Konrad Messmer
Effects of hemodilution on splanchnic perfusion and hepatorenal function. I. Splanchnic perfusion.
European journal of medical research 1997;2(10):413-8.
1997: SANJAY BATRA; Peter E Keipert; J D Bradley; N Simon Faithfull; SF Flaim
Use of a PFC-based oxygen carrier to lower the transfusion trigger in a canine model of hemodilution and surgical blood loss.
Advances in experimental medicine and biology 1997;411():377-81.
1996: Peter E Keipert; N Simon Faithfull; D J Roth; J D Bradley; SANJAY BATRA; P Jochelson; K E Flaim
Supporting tissue oxygenation during acute surgical bleeding using a perfluorochemical-based oxygen carrier.
Advances in experimental medicine and biology 1996;388():603-9.
1996: Joyce A Wahr; Adrianus Trouwborst; R K Spence; C P Henny; A C Cernaianu; Gregory P Graziano; Kevin K Tremper; K E Flaim; Peter E Keipert; N Simon Faithfull; J J Clymer
A pilot study of the effects of a perflubron emulsion, AF 0104, on mixed venous oxygen tension in anesthetized surgical patients.
Anesthesia and analgesia 1996;82(1):103-7.
1995: E C Johnson; B K Erickson; A Podolsky; E K Birks; Peter E Keipert; N Simon Faithfull; Peter D Wagner
Effects of a perfluorocarbon emulsion for enhanced O2 solubility on hemodynamics and O2 transport in dogs.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;79(5):1777-86.
1995: Susan A Stern; S C Dronen; Anthony J McGoron; X Wang; K Chaffins; R Millard; Peter E Keipert; N Simon Faithfull
Effect of supplemental perfluorocarbon administration on hypotensive resuscitation of severe uncontrolled hemorrhage.
The American journal of emergency medicine 1995;13(3):269-75.
1995: Peter E Keipert
Use of Oxygent, a perfluorochemical-based oxygen carrier, as an alternative to intraoperative blood transfusion.
Artificial cells, blood substitutes, and immobilization biotechnology 1995;23(3):381-94.
1994: Peter E Keipert; N Simon Faithfull; J D Bradley; D Y Hazard; J Hogan; M S Levisetti; R M Peters
Oxygen delivery augmentation by low-dose perfluorochemical emulsion during profound normovolemic hemodilution.
Advances in experimental medicine and biology 1994;345():197-204.
1994: A C Cernaianu; R K Spence; T V Vassilidze; J G Gallueci; T Gaprindashvili; A Olah; R L Weiss; JH Cilley; Peter E Keipert; N Simon Faithfull
Improvement in circulatory and oxygenation status by perflubron emulsion (Oxygent HT) in a canine model of surgical hemodilution.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(4):965-77.
1994: E Schutt; P Barber; T Fields; S Flaim; J Horodniak; Peter E Keipert; R Kinner; L Kornbrust; T Leakakos; T Pelura
Proposed mechanism of pulmonary gas trapping (PGT) following intravenous perfluorocarbon emulsion administration.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(4):1205-14.
1994: Peter E Keipert; S Otto; S F Flaim; Jeffry G Weers; E A Schutt; T J Pelura; D H Klein; T L Yaksh
Influence of perflubron emulsion particle size on blood half-life and febrile response in rats.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(4):1169-74.
1994: Peter E Keipert; N Simon Faithfull; J D Bradley; D Y Hazard; J Hogan; M S Levisetti; R M Peters
Enhanced oxygen delivery by perflubron emulsion during acute hemodilution.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(4):1161-7.
1994: N Simon Faithfull; G E Rhoades; Peter E Keipert; A S Ringle; Adrianus Trouwborst
A program to calculate mixed venous oxygen tension--a guide to transfusion?
Advances in experimental medicine and biology 1994;361():41-9.
1994: T E Gayeski; R J Connett; W A Voter; J L Frierson; Peter E Keipert; N Simon Faithfull
Whole animal, lung and muscle hemodynamics and function are maintained during and after Oxygent HT infusion.
Advances in experimental medicine and biology 1994;361():313-8.
1992: Michael C Hogan; D C Willford; Peter E Keipert; N Simon Faithfull; Peter D Wagner
Increased plasma O2 solubility improves O2 uptake of in situ dog muscle working maximally.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;73(6):2470-5.