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Debra Kelleher

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Philip Hölter; Debra K Kelleher; Stefanie Kunst; Carsten Sticht; Uwe Wolfrum; Tanja Wolloscheck; Rainer Spessert
The retinal clock drives the expression of Kcnv2, a channel essential for visual function and cone survival.
Debra K Kelleher; Helmut Piazena
The interpretation of clinical studies on the photodynamic treatment of actinic keratosis.
Isabella Spiwoks-Becker; Veronika Weyer; Tanja Wolloscheck; Debra K Kelleher; Oliver Rickes; Nils Rohleder; Rainer Spessert
Phosphodiesterase 10A in the rat pineal gland: localization, daily and seasonal regulation of expression and influence on signal transduction.

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2012: Philip Hölter; Debra K Kelleher; Stefanie Kunst; Carsten Sticht; Uwe Wolfrum; Tanja Wolloscheck; Rainer Spessert
The retinal clock drives the expression of Kcnv2, a channel essential for visual function and cone survival.
Investigative ophthalmology & visual science 2012;53(11):6947-54.
2012: Debra K Kelleher; Helmut Piazena
The interpretation of clinical studies on the photodynamic treatment of actinic keratosis.
German medical science : GMS e-journal 2012;10():Doc17.
2011: Isabella Spiwoks-Becker; Veronika Weyer; Tanja Wolloscheck; Debra K Kelleher; Oliver Rickes; Nils Rohleder; Rainer Spessert
Phosphodiesterase 10A in the rat pineal gland: localization, daily and seasonal regulation of expression and influence on signal transduction.
Neuroendocrinology 2011;94(2):113-23.
2010: Debra K Kelleher; Peter Vaupel
No sustained improvement in tumor oxygenation after localized mild hyperthermia.
Advances in experimental medicine and biology 2010;662():393-8.
2008: Oliver Thews; Birgit Gassner; Debra K Kelleher; Michael Gekle
Activity of drug efflux transporters in tumor cells under hypoxic conditions.
Advances in experimental medicine and biology 2008;614():157-64.
2007: Oliver Thews; Christine Lambert; Debra K Kelleher; Hans K Biesalski; Peter Vaupel; Juergen Frank
Impact of therapeutically induced reactive oxygen species and radical scavenging by alpha-tocopherol on tumor cell adhesion.
Oncology reports 2007;18(4):965-71.
2007: Oliver Thews; Birgit Gassner; Debra K Kelleher; Gerald Schwerdt; Michael Gekle
Impact of hypoxic and acidic extracellular conditions on cytotoxicity of chemotherapeutic drugs.
Advances in experimental medicine and biology 2007;599():155-61.
2007: Christopher Lotz; Debra K Kelleher; Birgit Gassner; Michael Gekle; Peter Vaupel; Oliver Thews
Role of the tumor microenvironment in the activity and expression of the p-glycoprotein in human colon carcinoma cells.
Oncology reports 2007;17(1):239-44.
2006: Oliver Thews; Birgit Gassner; Debra K Kelleher; Gerald Schwerdt; Michael Gekle
Impact of extracellular acidity on the activity of P-glycoprotein and the cytotoxicity of chemotherapeutic drugs.
Neoplasia (New York, N.Y.) 2006;8(2):143-52.
2006: Oliver Thews; Debra K Kelleher; Peter Vaupel
Changes in perfusion pattern of experimental tumors due to reduction in arterial oxygen partial pressure.
Advances in experimental medicine and biology 2006;578():363-8.
2005: Oliver Thews; Christine Lambert; Debra K Kelleher; Hans K Biesalski; Peter Vaupel; Juergen Frank
An in vivo tumor model expressing green fluorescent protein for the investigation of metastasis.
International journal of oncology 2005;27(3):705-12.
2005: Oliver Thews; Christine Lambert; Debra K Kelleher; Hans K Biesalski; Peter Vaupel; Jürgen Frank
Possible protective effects of alpha-tocopherol on enhanced induction of reactive oxygen species by 2-methoxyestradiol in tumors.
Advances in experimental medicine and biology 2005;566():349-55.
2004: Oliver Thews; Tanja Wolloscheck; Wolfgang Dillenburg; S Kraus; Debra K Kelleher; Moritz Konerding; Peter Vaupel
Microenvironmental adaptation of experimental tumours to chronic vs acute hypoxia.
British journal of cancer 2004;91(6):1181-9.
2004: Sabine Hawighorst-Knapstein; Claudia Fusshoeller; Cordula Franz; Kathrin Trautmann; Marcus Schmidt; Henryk Pilch; Goetz Schoenefuss; Paul Georg Knapstein; Heinz Koelbl; Debra K Kelleher; Peter Vaupel
The impact of treatment for genital cancer on quality of life and body image--results of a prospective longitudinal 10-year study.
Gynecologic oncology 2004;94(2):398-403.
2004: Sabine Hawighorst; Goetz Schoenefuss; Claudia Fusshoeller; Cordula Franz; Rudolf Seufert; Debra K Kelleher; Peter Vaupel; Paul Georg Knapstein; Heinz Koelbl
The physician-patient relationship before cancer treatment: a prospective longitudinal study.
Gynecologic oncology 2004;94(1):93-7.
2004: Debra K Kelleher; Oliver Thews; Avigdor Scherz; Yoram Salomon; Peter Vaupel
Perfusion, oxygenation status and growth of experimental tumors upon photodynamic therapy with Pd-bacteriopheophorbide.
International journal of oncology 2004;24(6):1505-11.
2003: Juergen Frank; Christine Lambert; Hans K Biesalski; Oliver Thews; Peter Vaupel; Debra K Kelleher
Intensified oxidative and nitrosative stress following combined ALA-based photodynamic therapy and local hyperthermia in rat tumors.
International journal of cancer. Journal international du cancer 2003;107(6):941-8.
2003: Debra K Kelleher; Oliver Thews; Avigdor Scherz; Yoram Salomon; Peter Vaupel
Combined hyperthermia and chlorophyll-based photodynamic therapy: tumour growth and metabolic microenvironment.
British journal of cancer 2003;89(12):2333-9.
2003: Debra K Kelleher; J Bastian; Oliver Thews; Peter Vaupel
Enhanced effects of aminolaevulinic acid-based photodynamic therapy through local hyperthermia in rat tumours.
British journal of cancer 2003;89(2):405-11.
2003: Peter Vaupel; Oliver Thews; Debra K Kelleher; Moritz Konerding
O(2) extraction is a key parameter determining the oxygenation status of malignant tumors and normal tissues.
International journal of oncology 2003;22(4):795-8.
2003: Oliver Thews; Debra K Kelleher; Peter Vaupel
Lack of association between tumor oxygenation and cell cycle distribution or proliferation kinetics in experimental sarcomas.
Advances in experimental medicine and biology 2003;540():245-50.
2003: Oliver Thews; Yanping Li; Debra K Kelleher; Britton Chance; Peter Vaupel
Microcirculatory function, tissue oxygenation, microregional redox status and ATP distribution in tumors upon localized infrared-A-hyperthermia at 42 degrees C.
Advances in experimental medicine and biology 2003;530():237-47.
2003: Oliver Thews; Debra K Kelleher; Norbert Esser; Stephan Kraus; Peter Vaupel
Lack of association between tumor hypoxia, GLUT-1 expression and glucose uptake in experimental sarcomas.
Advances in experimental medicine and biology 2003;510():57-61.
2002: Oliver Thews; M Hummel; Debra K Kelleher; Bernd Lecher; Peter Vaupel
Nifedipine improves blood flow and oxygen supply, but not steady-state oxygenation of tumours in perfusion pressure-controlled isolated limb perfusion.
British journal of cancer 2002;87(12):1462-9.
2002: C Lambert; Oliver Thews; Hans K Biesalski; P Vaupel; Debra K Kelleher; Juergen Frank
2-Methoxyestradiol enhances reactive oxygen species formation and increases the efficacy of oxygen radical generating tumor treatment.
European journal of medical research 2002;7(9):404-14.
2002: Oliver Thews; Debra K Kelleher; Peter Vaupel
Dynamics of tumor oxygenation and red blood cell flux in response to inspiratory hyperoxia combined with different levels of inspiratory hypercapnia.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2002;62(1):77-85.
2001: Oliver Thews; Debra K Kelleher; Peter Vaupel
No improvement in perfusion and oxygenation of experimental tumors upon application of vasodilator drugs.
International journal of oncology 2001;19(6):1243-7.
2001: P Vaupel; Oliver Thews; Debra K Kelleher
Pancreatic tumors show high levels of hypoxia: regarding Koong et al. IJROBP 2000;48:919-922.
International journal of radiation oncology, biology, physics 2001;50(4):1099-100.
2001: P Vaupel; Debra K Kelleher; Michael Höckel
Oxygen status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy.
Seminars in oncology 2001;28(2 Suppl 8):29-35.
2001: Oliver Thews; Debra K Kelleher; Peter Vaupel
Erythropoietin restores the anemia-induced reduction in cyclophosphamide cytotoxicity in rat tumors.
Cancer research 2001;61(4):1358-61.
2000: Oliver Thews; Debra K Kelleher; Peter Vaupel
Disparate responses of tumour vessels to angiotensin II: tumour volume-dependent effects on perfusion and oxygenation.
British journal of cancer 2000;83(2):225-31.
1999: Debra K Kelleher; Oliver Thews; J Rzeznik; Avigdor Scherz; Yoram Salomon; Peter Vaupel
Water-filtered infrared-A radiation: a novel technique for localized hyperthermia in combination with bacteriochlorophyll-based photodynamic therapy.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1999;15(6):467-74.
1999: Oliver Thews; Debra K Kelleher; M Hummel; Peter Vaupel
Can tumor oxygenation be improved by reducing cellular oxygen consumption.
Advances in experimental medicine and biology 1999;471():525-32.
1998: Debra K Kelleher; Oliver Thews; Peter Vaupel
Can erythropoietin improve tumor oxygenation?
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1998;174 Suppl 4():20-3.
1998: Peter Vaupel; Oliver Thews; Debra K Kelleher; M Hoeckel
Oxygenation of human tumors: the Mainz experience.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1998;174 Suppl 4():6-12.
1998: Debra K Kelleher; Oliver Thews; Peter Vaupel
Regional perfusion and oxygenation of tumors upon methylxanthine derivative administration.
International journal of radiation oncology, biology, physics 1998;42(4):861-4.
1998: Peter Vaupel; Debra K Kelleher; Oliver Thews
Modulation of tumor oxygenation.
International journal of radiation oncology, biology, physics 1998;42(4):843-8.
1998: Oliver Thews; R Koenig; Debra K Kelleher; Joachim Kutzner; Peter Vaupel
Enhanced radiosensitivity in experimental tumours following erythropoietin treatment of chemotherapy-induced anaemia.
British journal of cancer 1998;78(6):752-6.
1998: Oliver Thews; Debra K Kelleher; Bernd Lecher; Peter Vaupel
Blood flow, oxygenation, metabolic and energetic status in different clonal subpopulations of a rat rhabdomyosarcoma.
International journal of oncology 1998;13(2):205-11.
1998: Debra K Kelleher; C Nauth; Oliver Thews; W Krueger; Peter Vaupel
Localized hypothermia: impact on oxygenation, microregional perfusion, metabolic and bioenergetic status of subcutaneous rat tumours.
British journal of cancer 1998;78(1):56-61.
1998: Juergen Frank; Debra K Kelleher; Alfonso Pompella; Oliver Thews; Hans K Biesalski; P Vaupel
Enhancement of oxidative cell injury and antitumor effects of localized 44 degrees C hyperthermia upon combination with respiratory hyperoxia and xanthine oxidase.
Cancer research 1998;58(13):2693-8.
1998: Peter Vaupel; Oliver Thews; Debra K Kelleher; M Hoeckel
Current status of knowledge and critical issues in tumor oxygenation. Results from 25 years research in tumor pathophysiology.
Advances in experimental medicine and biology 1998;454():591-602.
1997: Debra K Kelleher; Oliver Thews; Peter Vaupel
Hypoxyradiotherapy: lack of experimental evidence for a preferential radioprotective effect on normal versus tumor tissue as shown by direct oxygenation measurements in experimental sarcomas.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1997;45(2):191-7.
1997: Oliver Thews; Debra K Kelleher; Bernd Lecher; Peter Vaupel
Effect of cell line and differentiation on the oxygenation status of experimental sarcomas.
Advances in experimental medicine and biology 1997;428():123-8.
1997: Oliver Thews; Debra K Kelleher; Peter Vaupel
Tumor oxygenation under normobaric and hyperbaric hyperoxia. Impact of various inspiratory CO2 concentrations.
Advances in experimental medicine and biology 1997;428():79-87.
1996: Oliver Thews; Debra K Kelleher; Peter Vaupel
Hyperbaric oxygenation of experimental tumors.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1996;172 Suppl 2():24-5.
1996: Debra K Kelleher; U Mattheinsen; Oliver Thews; Peter Vaupel
Blood flow, oxygenation, and bioenergetic status of tumors after erythropoietin treatment in normal and anemic rats.
Cancer research 1996;56(20):4728-34.
1996: Wolfgang Mueller-Klieser; Stefan Walenta; Debra K Kelleher; H Dinh; E Marx; Peter Vaupel
Tumour-growth inhibition by induced hyperglycaemia/hyperlactacidaemia and localized hyperthermia.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1996;12(4):501-11.
1996: Oliver Thews; Debra K Kelleher; Peter Vaupel
In vivo oxygen consumption rate of DS sarcoma cells on inhibition of DNA synthesis.
Cancer research 1996;56(9):2009-12.
1995: Debra K Kelleher; T Engel; Peter Vaupel
Changes in microregional perfusion, oxygenation, ATP and lactate distribution in subcutaneous rat tumours upon water-filtered IR-A hyperthermia.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1995;11(2):241-55.
1995: Debra K Kelleher; U Matthiensen; Oliver Thews; Peter Vaupel
Tumor oxygenation in anemic rats: effects of erythropoietin treatment versus red blood cell transfusion.
Acta oncologica (Stockholm, Sweden) 1995;34(3):379-84.
1995: Oliver Thews; Debra K Kelleher; Peter Vaupel
Modulation of spatial O2 tension distribution in experimental tumors by increasing arterial O2 supply.
Acta oncologica (Stockholm, Sweden) 1995;34(3):291-5.
1994: Debra K Kelleher; Peter Vaupel
Possible mechanisms involved in tumor radiosensitization following nicotinamide administration.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1994;32(1):47-53.
1994: Peter Vaupel; Debra K Kelleher; T Engel
Stable bioenergetic status despite substantial changes in blood flow and tissue oxygenation in a rat tumour.
British journal of cancer 1994;69(1):46-9.
1994: Debra K Kelleher; E Baussmann; E Friedrich; Peter Vaupel
The effect of erythropoietin on tumor oxygenation in normal and anemic rats.
Advances in experimental medicine and biology 1994;345():517-24.
1994: Debra K Kelleher; Peter Vaupel
The effect of nicotinamide on microcirculatory function, tissue oxygenation and bioenergetic status in rat tumors.
Advances in experimental medicine and biology 1994;345():395-402.
1994: Peter Vaupel; Debra K Kelleher; T Engel
Do changes in tumor blood flow necessarily lead to changes in tissue oxygenation and in bioenergetic status?
Advances in experimental medicine and biology 1994;361():607-11.
1993: Debra K Kelleher; Peter Vaupel
Nicotinamide exerts different acute effects on microcirculatory function and tissue oxygenation in rat tumors.
International journal of radiation oncology, biology, physics 1993;26(1):95-102.
1992: Peter Vaupel; Debra K Kelleher; W Krüger
Water-filtered infrared-A radiation: a novel technique to heat superficial tumors.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1992;168(11):633-9.