Gary Kelloff

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Barker A D; Sigman C C; Kelloff G J; Hylton N M; Berry D A; Esserman L J
I-SPY 2: an adaptive breast cancer trial design in the setting of neoadjuvant chemotherapy.
Kelloff Gary J; Choyke Peter; Coffey Donald S;
Challenges in clinical prostate cancer: role of imaging.
Kelloff Gary J; Sigman Caroline C; Contag Christopher H
Early detection of oral neoplasia: watching with new eyes.

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All Publications

2009: Barker A D; Sigman C C; Kelloff G J; Hylton N M; Berry D A; Esserman L J
I-SPY 2: an adaptive breast cancer trial design in the setting of neoadjuvant chemotherapy.
Clinical pharmacology and therapeutics 2009;86(1):97-100.
2009: Kelloff Gary J; Choyke Peter; Coffey Donald S;
Challenges in clinical prostate cancer: role of imaging.
AJR. American journal of roentgenology 2009;192(6):1455-70.
2009: Kelloff Gary J; Sigman Caroline C; Contag Christopher H
Early detection of oral neoplasia: watching with new eyes.
Cancer prevention research (Philadelphia, Pa.) 2009;2(5):405-8.
2008: Eckelman William C; Reba Richard C; Kelloff Gary J
Targeted imaging: an important biomarker for understanding disease progression in the era of personalized medicine.
Drug discovery today 2008;13(17-18):748-59.
2007: Hoffman John M; Gambhir Sanjiv S; Kelloff Gary J
Regulatory and reimbursement challenges for molecular imaging.
Radiology 2007;245(3):645-60.
2007: Kelloff Gary J; Sigman Caroline C
Assessing intraepithelial neoplasia and drug safety in cancer-preventive drug development.
Nature reviews. Cancer 2007;7(7):508-18.
2006: El-Deiry Wafik S; Sigman Caroline C; Kelloff Gary J
Imaging and oncologic drug development.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(20):3261-73.
2005: Steele Vernon E; Kelloff Gary J
Development of cancer chemopreventive drugs based on mechanistic approaches.
Mutation research 2005;591(1-2):16-23.
2005: Kelloff Gary J; Krohn Kenneth A; Larson Steven M; Weissleder Ralph; Mankoff David A; Hoffman John M; Link Jeanne M; Guyton Kathryn Z; Eckelman William C; Scher Howard I; O'Shaughnessy Joyce; Cheson Bruce D; Sigman Caroline C; Tatum James L; Mills George Q; Sullivan Daniel C; Woodcock Janet
The progress and promise of molecular imaging probes in oncologic drug development.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(22):7967-85.
2005: Simeone Ann-Marie; Deng Chu-Xia; Kelloff Gary J; Steele Vernon E; Johnson Marcella M; Tari Ana M
N-(4-Hydroxyphenyl)retinamide is more potent than other phenylretinamides in inhibiting the growth of BRCA1-mutated breast cancer cells.
Carcinogenesis 2005;26(5):1000-7.
2005: Kelloff Gary J; Hoffman John M; Johnson Bruce; Scher Howard I; Siegel Barry A; Cheng Edward Y; Cheson Bruce D; O'shaughnessy Joyce; Guyton Kathryn Z; Mankoff David A; Shankar Lalitha; Larson Steven M; Sigman Caroline C; Schilsky Richard L; Sullivan Daniel C
Progress and promise of FDG-PET imaging for cancer patient management and oncologic drug development.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(8):2785-808.
2005: Sullivan Daniel C; Kelloff Gary
Seeing into cells. The promise of in vivo molecular imaging in oncology.
EMBO reports 2005;6(4):292-6.
2005: Kelloff Gary J; Sigman Caroline C
New science-based endpoints to accelerate oncology drug development.
European journal of cancer (Oxford, England : 1990) 2005;41(4):491-501.
2004: Christov K T; Moon R C; Lantvit D D; Boone C W; Kelloff G J; Steele V E; Lubet R A; Pezzuto J M
Prostate intraepithelial neoplasia in Noble rats, a potential intermediate endpoint for chemoprevention studies.
European journal of cancer (Oxford, England : 1990) 2004;40(9):1404-11.
2004: Kelloff Gary J; Coffey Donald S; Chabner Bruce A; Dicker Adam P; Guyton Kathryn Z; Nisen Perry D; Soule Howard R; D'Amico Anthony V
Prostate-specific antigen doubling time as a surrogate marker for evaluation of oncologic drugs to treat prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(11):3927-33.
2004: Rustin Gordon J S; Bast Robert C; Kelloff Gary J; Barrett J Carl; Carter Stephen K; Nisen Perry D; Sigman Caroline C; Parkinson David R; Ruddon Raymond W
Use of CA-125 in clinical trial evaluation of new therapeutic drugs for ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(11):3919-26.
2004: Kelloff Gary J; Schilsky Richard L; Alberts David S; Day Robert W; Guyton Kathryn Z; Pearce Homer L; Peck Jonathan C; Phillips Robert; Sigman Caroline C
Colorectal adenomas: a prototype for the use of surrogate end points in the development of cancer prevention drugs.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(11):3908-18.
2004: Woude George F Vande; Kelloff Gary J; Ruddon Raymond W; Koo Han-Mo; Sigman Caroline C; Barrett J Carl; Day Robert W; Dicker Adam P; Kerbel Robert S; Parkinson David R; Slichenmyer William J
Reanalysis of cancer drugs: old drugs, new tricks.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(11):3897-907.
2004: Park John W; Kerbel Robert S; Kelloff Gary J; Barrett J Carl; Chabner Bruce A; Parkinson David R; Peck Jonathan; Ruddon Raymond W; Sigman Caroline C; Slamon Dennis J
Rationale for biomarkers and surrogate end points in mechanism-driven oncology drug development.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(11):3885-96.
2004: Kelloff Gary J; Bast Robert C; Coffey Donald S; D'Amico Anthony V; Kerbel Robert S; Park John W; Ruddon Raymond W; Rustin Gordon J S; Schilsky Richard L; Sigman Caroline C; Woude George F Vande
Biomarkers, surrogate end points, and the acceleration of drug development for cancer prevention and treatment: an update prologue.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(11):3881-4.
2003: Sabichi Anita L; Xu Hui; Fischer Susan; Zou Changchan; Yang Xiulan; Steele Vernon E; Kelloff Gary J; Lotan Reuben; Clifford John L
Retinoid receptor-dependent and independent biological activities of novel fenretinide analogues and metabolites.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(12):4606-13.
2003: Kelloff Gary J; O'Shaughnessy Joyce A; Gordon Gary B; Hawk Ernest T; Sigman Caroline C
Counterpoint: Because some surrogate end point biomarkers measure the neoplastic process they will have high utility in the development of cancer chemopreventive agents against sporadic cancers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(7):593-6.
2002: Clarke Laurence P; Baker Houston; Kelloff Gary; Sullivan Daniel
RFA:CA-03-002: network for translational research: optical imaging.
Medical physics 2002;29(12):2959.
2002: Christov Konstantin T; Moon Richard C; Lantvit Daniel D; Boone Charles W; Steele Vernon E; Lubet Ronald A; Kelloff Gary J; Pezzuto John M
9-cis-retinoic acid but not 4-(hydroxyphenyl)retinamide inhibits prostate intraepithelial neoplasia in Noble rats.
Cancer research 2002;62(18):5178-82.
2002: Phillips R K S; Wallace M H; Lynch P M; Hawk E; Gordon G B; Saunders B P; Wakabayashi N; Shen Y; Zimmerman S; Godio L; Rodrigues-Bigas M; Su L-K; Sherman J; Kelloff G; Levin B; Steinbach G;
A randomised, double blind, placebo controlled study of celecoxib, a selective cyclooxygenase 2 inhibitor, on duodenal polyposis in familial adenomatous polyposis.
Gut 2002;50(6):857-60.
2002: O'Shaughnessy Joyce A; Kelloff Gary J; Gordon Gary B; Dannenberg Andrew J; Hong Waun Ki; Fabian Carol J; Sigman Caroline C; Bertagnolli Monica M; Stratton Steven P; Lam Stephen; Nelson William G; Meyskens Frank L; Alberts David S; Follen Michele; Rustgi Anil K; Papadimitrakopoulou Vali; Scardino Peter T; Gazdar Adi F; Wattenberg Lee W; Sporn Michael B; Sakr Wael A; Lippman Scott M; Von Hoff Daniel D
Treatment and prevention of intraepithelial neoplasia: an important target for accelerated new agent development.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(2):314-46.
2002: Kelloff Gary J; Higley Howard R; Brawer Michael K; Lucia M Scott; Sigman Caroline C; Crawford E David
Chemoprevention strategies in the prostate: an overview.
Reviews in urology 2002;4(2):69-77.
2001: Green J E; Shibata M A; Shibata E; Moon R C; Anver M R; Kelloff G; Lubet R
2-difluoromethylornithine and dehydroepiandrosterone inhibit mammary tumor progression but not mammary or prostate tumor initiation in C3(1)/SV40 T/t-antigen transgenic mice.
Cancer research 2001;61(20):7449-55.
2001: D'Ambrosio S M; Gibson-D'Ambrosio R E; Wani G; Casto B; Milo G E; Kelloff G J; Steele V E
Modulation of Ki67, p53 and RARbeta expression in normal, premalignant and malignant human oral epithelial cells by chemopreventive agents.
Anticancer research 2001;21(5):3229-35.
2001: Mehta R G; Bhat K P; Hawthorne M E; Kopelovich L; Mehta R R; Christov K; Kelloff G J; Steele V E; Pezzuto J M
Induction of atypical ductal hyperplasia in mouse mammary gland organ culture.
Journal of the National Cancer Institute 2001;93(14):1103-6.
2001: Sun S Y; Yue P; Kelloff G J; Steele V E; Lippman S M; Hong W K; Lotan R
Identification of retinamides that are more potent than N-(4-hydroxyphenyl)retinamide in inhibiting growth and inducing apoptosis of human head and neck and lung cancer cells.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(6):595-601.
2001: Clifford J L; Sabichi A L; Zou C; Yang X; Steele V E; Kelloff G J; Lotan R; Lippman S M
Effects of novel phenylretinamides on cell growth and apoptosis in bladder cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(4):391-5.
2001: Weiss H L; Urban D A; Grizzle W E; Cronin K A; Freedman L S; Kelloff G J; Lieberman R
Bayesian monitoring of a phase 2 chemoprevention trial in high-risk cohorts for prostate cancer.
Urology 2001;57(4 Suppl 1):220-3.
2001: Kelloff G J; Lieberman R; Steele V E; Boone C W; Lubet R A; Kopelovich L; Malone W A; Crowell J A; Higley H R; Sigman C C
Agents, biomarkers, and cohorts for chemopreventive agent development in prostate cancer.
Urology 2001;57(4 Suppl 1):46-51.
2001: Lin L; Wang Y; Bergman G; Kelloff G J; Lubet R A; You M
Detection of differentially expressed genes in mouse lung adenocarcinomas.
Experimental lung research 2001;27(3):217-29.
2001: Hoque A; Lippman S M; Boiko I V; Atkinson E N; Sneige N; Sahin A; Weber D M; Risin S; Lagios M D; Schwarting R; Colburn W J; Dhingra K; Follen M; Kelloff G J; Boone C W; Hittelman W N
Quantitative nuclear morphometry by image analysis for prediction of recurrence of ductal carcinoma in situ of the breast.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(3):249-59.
2001: Herzog C R; Crist K A; Sabourin C L; Kelloff G J; Boone C W; Stoner G D; You M
Chromosome 3p tumor-suppressor gene alterations in cervical carcinomas.
Molecular carcinogenesis 2001;30(3):159-68.
2001: Rodríguez-Burford C; Lubet R A; Steele V E; Eto I; Bandy M; Juliana M M; Weiss H L; Grizzle W E; Kelloff G J; Grubbs C J
Effects of acute and chronic body weight gain reductions in the evaluation of agents for efficacy in mammary cancer prevention.
Oncology reports 2001;8(2):373-9.
2001: Kelloff G J; Sigman C C; Hawk E T; Johnson K M; Crowell J A; Guyton K Z
Surrogate end-point biomarkers in chemopreventive drug development.
IARC scientific publications 2001;154():13-26.
2000: Liu J; Gu P; Bergman G; Kelloff G J; Boone C W; You M; Wang Y
Detection of genetic alterations in mouse lung adenocarcinomas by two-dimensional gel electrophoresis.
Experimental lung research 2000;26(8):651-8.
2000: Boone C W; Stoner G D; Bacus J V; Kagan V; Morse M A; Kelloff G J; Bacus J W
Chemoprevention with theaflavins of rat esophageal intraepithelial neoplasia quantitatively monitored by image tile analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000;9(11):1149-54.
2000: Grubbs C J; Lubet R A; Koki A T; Leahy K M; Masferrer J L; Steele V E; Kelloff G J; Hill D L; Seibert K
Celecoxib inhibits N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder cancers in male B6D2F1 mice and female Fischer-344 rats.
Cancer research 2000;60(20):5599-602.
2000: Singletary E; Lieberman R; Atkinson N; Sneige N; Sahin A; Tolley S; Colchin M; Bevers T; Stelling C; Fornage B; Fritsche H; Hittelman W; Kelloff G; Lippman S M
Novel translational model for breast cancer chemoprevention study: accrual to a presurgical intervention with tamoxifen and N-[4-hydroxyphenyl] retinamide.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000;9(10):1087-90.
2000: Cho K H; Pezzuto J M; Bolton J L; Steele V E; Kelloff G J; Lee S K; Constantinou A
Selection of cancer chemopreventive agents based on inhibition of topoisomerase II activity.
European journal of cancer (Oxford, England : 1990) 2000;36(16):2146-56.
2000: Steele V E; Holmes C A; Hawk E T; Kopelovich L; Lubet R A; Crowell J A; Sigman C C; Kelloff G J
Potential use of lipoxygenase inhibitors for cancer chemoprevention.
Expert opinion on investigational drugs 2000;9(9):2121-38.
2000: Jacoby R F; Seibert K; Cole C E; Kelloff G; Lubet R A
The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis.
Cancer research 2000;60(18):5040-4.
2000: Shilkaitis A; Graves J; Mehta R R; Hu L; You M; Lubet R; Steele V; Kelloff G; Christov K
Bcl-2 and Bax are differentially expressed in hyperplastic, premalignant, and malignant lesions of mammary carcinogenesis.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2000;11(8):437-45.
2000: D'Ambrosio S M; Gibson-D'Ambrosio R; Milo G E; Casto B; Kelloff G J; Steele V E
Differential response of normal, premalignant and malignant human oral epithelial cells to growth inhibition by chemopreventive agents.
Anticancer research 2000;20(4):2273-80.
2000: Hansen L A; Sigman C C; Andreola F; Ross S A; Kelloff G J; De Luca L M
Retinoids in chemoprevention and differentiation therapy.
Carcinogenesis 2000;21(7):1271-9.
2000: Boone C W; Stoner G D; Bacus J V; Kagan V; Morse M A; Kelloff G J; Bacus J W
Quantitative grading of rat esophageal carcinogenesis using computer-assisted image tile analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000;9(5):495-500.
2000: Jacoby R F; Cole C E; Tutsch K; Newton M A; Kelloff G; Hawk E T; Lubet R A
Chemopreventive efficacy of combined piroxicam and difluoromethylornithine treatment of Apc mutant Min mouse adenomas, and selective toxicity against Apc mutant embryos.
Cancer research 2000;60(7):1864-70.
2000: Christov K; Shilkaitis A; Green A; Mehta R G; Grubbs C; Kelloff G; Lubet R
Cellular responses of mammary carcinomas to aromatase inhibitors: effects of vorozole.
Breast cancer research and treatment 2000;60(2):117-28.
2000: Kelloff G J; Crowell J A; Steele V E; Lubet R A; Malone W A; Boone C W; Kopelovich L; Hawk E T; Lieberman R; Lawrence J A; Ali I; Viner J L; Sigman C C
Progress in cancer chemoprevention: development of diet-derived chemopreventive agents.
The Journal of nutrition 2000;130(2S Suppl):467S-471S.
2000: Zhang Z; Liu Q; Lantry L E; Wang Y; Kelloff G J; Anderson M W; Wiseman R W; Lubet R A; You M
A germ-line p53 mutation accelerates pulmonary tumorigenesis: p53-independent efficacy of chemopreventive agents green tea or dexamethasone/myo-inositol and chemotherapeutic agents taxol or adriamycin.
Cancer research 2000;60(4):901-7.
2000: Kelloff G J; Sigman C C; Johnson K M; Boone C W; Greenwald P; Crowell J A; Hawk E T; Doody L A
Perspectives on surrogate end points in the development of drugs that reduce the risk of cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000;9(2):127-37.
2000: Shilkaitis A; Green A; Steele V; Lubet R; Kelloff G; Christov K
Neoplastic transformation of mammary epithelial cells in rats is associated with decreased apoptotic cell death.
Carcinogenesis 2000;21(2):227-33.
2000: Reddy B S; Hirose Y; Lubet R; Steele V; Kelloff G; Paulson S; Seibert K; Rao C V
Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis.
Cancer research 2000;60(2):293-7.
2000: van Stolk R; Stoner G; Hayton W L; Chan K; DeYoung B; Kresty L; Kemmenoe B H; Elson P; Rybicki L; Church J; Provencher K; McLain D; Hawk E; Fryer B; Kelloff G; Ganapathi R; Budd G T
Phase I trial of exisulind (sulindac sulfone, FGN-1) as a chemopreventive agent in patients with familial adenomatous polyposis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(1):78-89.
2000: Steele V E; Kelloff G J; Balentine D; Boone C W; Mehta R; Bagheri D; Sigman C C; Zhu S; Sharma S
Comparative chemopreventive mechanisms of green tea, black tea and selected polyphenol extracts measured by in vitro bioassays.
Carcinogenesis 2000;21(1):63-7.
2000: Lawrence J A; Malpas P B; Sigman C C; Kelloff G J
Clinical development of estrogen modulators for breast cancer chemoprevention in premenopausal vs. postmenopausal women.
Journal of cellular biochemistry. Supplement 2000;34():103-14.
2000: Boone C W; Kelloff G J
Endpoint markers for cancer chemoprevention trials derived from the lesion of precancer (intraepithelial neoplasia) measured by computer-assisted quantitative image analysis.
Journal of cellular biochemistry. Supplement 2000;34():67-72.
2000: Kelloff G J
Perspectives on cancer chemoprevention research and drug development.
Advances in cancer research 2000;78():199-334.
1999: Kelloff G J; Sigman C C; Greenwald P
Cancer chemoprevention: progress and promise.
European journal of cancer (Oxford, England : 1990) 1999;35(14):2031-8.
1999: Kelloff G J; Sigman C C; Greenwald P
Cancer chemoprevention: progress and promise.
European journal of cancer (Oxford, England : 1990) 1999;35(13):1755-62.
1999: Li H; Kramer P M; Lubet R A; Steele V E; Kelloff G J; Pereira M A
Termination of piroxicam treatment and the occurrence of azoxymethane-induced colon cancer in rats.
Cancer letters 1999;147(1-2):187-93.
1999: Bacus J W; Boone C W; Bacus J V; Follen M; Kelloff G J; Kagan V; Lippman S M
Image morphometric nuclear grading of intraepithelial neoplastic lesions with applications to cancer chemoprevention trials.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1999;8(12):1087-94.
1999: Cronin K A; Freedman L S; Lieberman R; Weiss H L; Beenken S W; Kelloff G J
Bayesian monitoring of phase II trials in cancer chemoprevention.
Journal of clinical epidemiology 1999;52(8):705-11.
1999: Fischer S M; Lo H H; Gordon G B; Seibert K; Kelloff G; Lubet R A; Conti C J
Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis.
Molecular carcinogenesis 1999;25(4):231-40.
1999: Reddy B S; Kawamori T; Lubet R; Steele V; Kelloff G; Rao C V
Chemopreventive effect of S-methylmethane thiosulfonate and sulindac administered together during the promotion/progression stages of colon carcinogenesis.
Carcinogenesis 1999;20(8):1645-8.
1999: Reddy B S; Kawamori T; Lubet R A; Steele V E; Kelloff G J; Rao C V
Chemopreventive efficacy of sulindac sulfone against colon cancer depends on time of administration during carcinogenic process.
Cancer research 1999;59(14):3387-91.
1999: Steele V E; Holmes C A; Hawk E T; Kopelovich L; Lubet R A; Crowell J A; Sigman C C; Kelloff G J
Lipoxygenase inhibitors as potential cancer chemopreventives.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1999;8(5):467-83.
1999: Bednarek A; Shilkaitis A; Green A; Lubet R; Kelloff G; Christov K; Aldaz C M
Suppression of cell proliferation and telomerase activity in 4-(hydroxyphenyl)retinamide-treated mammary tumors.
Carcinogenesis 1999;20(5):879-83.
1999: Steele V E; Bagheri D; Balentine D A; Boone C W; Mehta R; Morse M A; Sharma S; Sigman C C; Stoner G D; Wargovich M J; Weisburger J H; Zhu S; Kelloff G J
Preclinical efficacy studies of green and black tea extracts.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1999;220(4):210-2.
1999: Li H; Schut H A; Conran P; Kramer P M; Lubet R A; Steele V E; Hawk E E; Kelloff G J; Pereira M A
Prevention by aspirin and its combination with alpha-difluoromethylornithine of azoxymethane-induced tumors, aberrant crypt foci and prostaglandin E2 levels in rat colon.
Carcinogenesis 1999;20(3):425-30.
1999: Sneige N; Lagios M D; Schwarting R; Colburn W; Atkinson E; Weber D; Sahin A; Kemp B; Hoque A; Risin S; Sabichi A; Boone C; Dhingra K; Kelloff G; Lippman S
Interobserver reproducibility of the Lagios nuclear grading system for ductal carcinoma in situ.
Human pathology 1999;30(3):257-62.
1999: Lantry L E; Zhang Z; Crist K A; Wang Y; Kelloff G J; Lubet R A; You M
5-Aza-2'-deoxycytidine is chemopreventive in a 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone-induced primary mouse lung tumor model.
Carcinogenesis 1999;20(2):343-6.
1999: Zheng Y; Kramer P M; Lubet R A; Steele V E; Kelloff G J; Pereira M A
Effect of retinoids on AOM-induced colon cancer in rats: modulation of cell proliferation, apoptosis and aberrant crypt foci.
Carcinogenesis 1999;20(2):255-60.
1999: Kawamori T; Lubet R; Steele V E; Kelloff G J; Kaskey R B; Rao C V; Reddy B S
Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer.
Cancer research 1999;59(3):597-601.
1999: Lee S K; Song L; Mata-Greenwood E; Kelloff G J; Steele V E; Pezzuto J M
Modulation of in vitro biomarkers of the carcinogenic process by chemopreventive agents.
Anticancer research 1999;19(1A):35-44.
1999: Rodríguez-Burford C; Lubet R A; Eto I; Juliana M M; Kelloff G J; Grubbs C J; Steele V E
Effect of reduced body weight gain on the evaluation of chemopreventive agents in the methylnitrosourea-induced mammary cancer model.
Carcinogenesis 1999;20(1):71-6.
1999: Stoner G D; Budd G T; Ganapathi R; DeYoung B; Kresty L A; Nitert M; Fryer B; Church J M; Provencher K; Pamukcu R; Piazza G; Hawk E; Kelloff G; Elson P; van Stolk R U
Sulindac sulfone induced regression of rectal polyps in patients with familial adenomatous polyposis.
Advances in experimental medicine and biology 1999;470():45-53.
1999: Kelloff G J; Crowell J A; Steele V E; Lubet R A; Boone C W; Malone W A; Hawk E T; Lieberman R; Lawrence J A; Kopelovich L; Ali I; Viner J L; Sigman C C
Progress in cancer chemoprevention.
Annals of the New York Academy of Sciences 1999;889():1-13.
1999: Urban D; Myers R; Manne U; Weiss H; Mohler J; Perkins D; Markiewicz M; Lieberman R; Kelloff G; Marshall M; Grizzle W
Evaluation of biomarker modulation by fenretinide in prostate cancer patients.
European urology 1999;35(5-6):429-38.
1999: Kelloff G J; Lieberman R; Steele V E; Boone C W; Lubet R A; Kopelovitch L; Malone W A; Crowell J A; Sigman C C
Chemoprevention of prostate cancer: concepts and strategies.
European urology 1999;35(5-6):342-50.
1998: Steele V E; Boone C W; Lubet R A; Crowell J A; Holmes C A; Sigman C C; Kelloff G J
Preclinical drug development paradigms for chemopreventives.
Hematology/oncology clinics of North America 1998;12(5):943-61, v-vi.
1998: Parshad R; Sanford K K; Price F M; Steele V E; Tarone R E; Kelloff G J; Boone C W
Protective action of plant polyphenols on radiation-induced chromatid breaks in cultured human cells.
Anticancer research 1998;18(5A):3263-6.
1998: Lubet R A; Steele V E; DeCoster R; Bowden C; You M; Juliana M M; Eto I; Kelloff G J; Grubbs C J
Chemopreventive effects of the aromatase inhibitor vorozole (R 83842) in the methylnitrosourea-induced mammary cancer model.
Carcinogenesis 1998;19(8):1345-51.
1998: Sabourin C L; Wang Q S; Ralston S L; Evans J; Coate J; Herzog C R; Jones S L; Weghorst C M; Kelloff G J; Lubet R A; You M; Stoner G D
Expression of cell cycle proteins in 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung tumors.
Experimental lung research 1998;24(4):499-521.
1998: Boone C W; Steele V E; Gaylor D; Kelloff G J
Use of Druckrey analysis to quantitatively evaluate the chemopreventive efficacy of N-difluoromethylornithine (DFMO), a prototype proliferation inhibitor.
Mutation research 1998;402(1-2):173-7.
1998: Lubet R A; Gordon G B; Prough R A; Lei X D; You M; Wang Y; Grubbs C J; Steele V E; Kelloff G J; Thomas C F; Moon R D
Modulation of methylnitrosourea-induced breast cancer in Sprague Dawley rats by dehydroepiandrosterone: dose-dependent inhibition, effects of limited exposure, effects on peroxisomal enzymes, and lack of effects on levels of Ha-Ras mutations.
Cancer research 1998;58(5):921-6.
1998: Conaway C C; Jiao D; Kelloff G J; Steele V E; Rivenson A; Chung F L
Chemopreventive potential of fumaric acid, N-acetylcysteine, N-(4-hydroxyphenyl) retinamide and beta-carotene for tobacco-nitrosamine-induced lung tumors in A/J mice.
Cancer letters 1998;124(1):85-93.
1998: Li H; Kramer P M; Lubet R A; Steele V E; Kelloff G J; Pereira M A
Effect of calcium on azoxymethane-induced aberrant crypt foci and cell proliferation in the colon of rats.
Cancer letters 1998;124(1):39-46.
1998: Lieberman R; Crowell J A; Hawk E T; Boone C W; Sigman C C; Kelloff G J
Development of new cancer chemoprevention agents: role of pharmacokinetic/pharmacodynamic and intermediate endpoint biomarker monitoring.
Clinical chemistry 1998;44(2):420-7.
1998: Kelloff G J; Lubet R A; Lieberman R; Eisenhauer K; Steele V E; Crowell J A; Hawk E T; Boone C W; Sigman C C
Aromatase inhibitors as potential cancer chemopreventives.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(1):65-78.
1998: Weisburger J H; Rivenson A; Aliaga C; Reinhardt J; Kelloff G J; Boone C W; Steele V E; Balentine D A; Pittman B; Zang E
Effect of tea extracts, polyphenols, and epigallocatechin gallate on azoxymethane-induced colon cancer.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1998;217(1):104-8.
1997: Zheng Y; Kramer P M; Olson G; Lubet R A; Steele V E; Kelloff G J; Pereira M A
Prevention by retinoids of azoxymethane-induced tumors and aberrant crypt foci and their modulation of cell proliferation in the colon of rats.
Carcinogenesis 1997;18(11):2119-25.
1997: Boone C W; Bacus J W; Bacus J V; Steele V E; Kelloff G J
Properties of intraepithelial neoplasia relevant to cancer chemoprevention and to the development of surrogate end points for clinical trials.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1997;216(2):151-65.
1997: Rao C V; Wang C X; Simi B; Lubet R; Kelloff G; Steele V; Reddy B S
Enhancement of experimental colon cancer by genistein.
Cancer research 1997;57(17):3717-22.
1997: Lubet R A; Steele V E; Eto I; Juliana M M; Kelloff G J; Grubbs C J
Chemopreventive efficacy of anethole trithione, N-acetyl-L-cysteine, miconazole and phenethylisothiocyanate in the DMBA-induced rat mammary cancer model.
International journal of cancer. Journal international du cancer 1997;72(1):95-101.
1997: Matzinger S A; Chen B; Wang Y; Crist K A; Stoner G D; Kelloff G J; Lubet R A; You M
Tissue-specific expression of the K-ras allele from the A/J parent in (A/J x TSG-p53) F1 mice.
Gene 1997;188(2):261-9.
1997: Kelloff G J; Lubet R A; Fay J R; Steele V E; Boone C W; Crowell J A; Sigman C C
Farnesyl protein transferase inhibitors as potential cancer chemopreventives.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(4):267-82.
1997: Samaha H S; Kelloff G J; Steele V; Rao C V; Reddy B S
Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion.
Cancer research 1997;57(7):1301-5.
1997: Reddy B S; Wang C X; Samaha H; Lubet R; Steele V E; Kelloff G J; Rao C V
Chemoprevention of colon carcinogenesis by dietary perillyl alcohol.
Cancer research 1997;57(3):420-5.
1997: Crowell J A; Page J G; Rodman L E; Heath J E; Goldenthal E I; Hall L B; Kelloff G J
Chronic toxicity studies of 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione, a potential chemopreventive agent.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1997;35(1):9-21.
1997: Crist K A; Wang Y; Lubet R A; Steele V E; Kelloff G J; You M
Effect of early vs. late administration of 4-hydroxyphenylretinamide (4-HPR) on N-methyl-N-nitrosourea (MNU)-induced mammary tumorigenesis.
Journal of cellular biochemistry. Supplement 1997;27():92-9.
1997: Lantry L E; Zhang Z; Gao F; Crist K A; Wang Y; Kelloff G J; Lubet R A; You M
Chemopreventive effect of perillyl alcohol on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced tumorigenesis in (C3H/HeJ X A/J)F1 mouse lung.
Journal of cellular biochemistry. Supplement 1997;27():20-5.
1997: Hu L; Lin L; Crist K A; Kelloff G J; Steele V E; Lubet R A; You M; Wang Y
Detection of differentially expressed genes in methylnitrosourea-induced rat mammary adenocarcinomas.
Journal of cellular biochemistry. Supplement 1997;28-29():117-24.
1997: Bacus J W; Bacus J V; Stoner G D; Moon R C; Kelloff G J; Boone C W
Quantitation of preinvasive neoplastic progression in animal models of chemical carcinogenesis.
Journal of cellular biochemistry. Supplement 1997;28-29():21-38.
1997: Boone C W; Bacus J W; Bacus J V; Steele V E; Kelloff G J
Properties of intraepithelial neoplasia relevant to the development of cancer chemopreventive agents.
Journal of cellular biochemistry. Supplement 1997;28-29():1-20.
1997: Morse M A; Kresty L A; Steele V E; Kelloff G J; Boone C W; Balentine D A; Harbowy M E; Stoner G D
Effects of theaflavins on N-nitrosomethylbenzylamine-induced esophageal tumorigenesis.
Nutrition and cancer 1997;29(1):7-12.
1997: Boone C W; Kelloff G J
Biomarker end-points in cancer chemoprevention trials.
IARC scientific publications 1997;(142):273-80.
1997: Kelloff G J; Boone C W; Crowell J A; Nayfield S G; Hawk E T; Steele V E; Lubet R A; Sigman C C
Perspectives and progress in development of breast cancer chemopreventive drugs.
Progress in clinical and biological research 1997;396():159-83.
1996: Kelloff G J; Hawk E T; Crowell J A; Boone C W; Steele V E; Lubet R A; Sigman C C
Perspectives on chemoprevention agent selection and short-term clinical prevention trials.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 1996;5 Suppl 2():79-85.
1996: Karp J E; Chiarodo A; Brawley O; Kelloff G J
Prostate cancer prevention: investigational approaches and opportunities.
Cancer research 1996;56(24):5547-56.
1996: McCormick D L; Johnson W D; Rao K V; Bowman-Gram T; Steele V E; Lubet R A; Kelloff G J
Comparative activity of N-(4-hydroxyphenyl)-all-trans-retinamide and alpha-difluoromethylornithine as inhibitors of lymphoma induction in PIM transgenic mice.
Carcinogenesis 1996;17(11):2513-7.
1996: Kelloff G J; Hawk E T; Crowell J A; Boone C W; Nayfield S G; Perloff M; Steele V E; Lubet R A
Strategies for identification and clinical evaluation of promising chemopreventive agents.
Oncology (Williston Park, N.Y.) 1996;10(10):1471-84; discussion 1484-8.
1996: Kelloff G J; Fay J R; Steele V E; Lubet R A; Boone C W; Crowell J A; Sigman C C
Epidermal growth factor receptor tyrosine kinase inhibitors as potential cancer chemopreventives.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1996;5(8):657-66.
1996: Rao C V; Rivenson A; Zang E; Steele V; Kelloff G; Reddy B S
Inhibition of 2-Amino-1-methyl-6-phenylimidazo[4,5]pyridine-induced lymphoma formation by oltipraz.
Cancer research 1996;56(15):3395-8.
1996: Rao K V; Detrisac C J; Steele V E; Hawk E T; Kelloff G J; McCormick D L
Differential activity of aspirin, ketoprofen and sulindac as cancer chemopreventive agents in the mouse urinary bladder.
Carcinogenesis 1996;17(7):1435-8.
1996: Pereira M A; Grubbs C J; Barnes L H; Li H; Olson G R; Eto I; Juliana M; Whitaker L M; Kelloff G J; Steele V E; Lubet R A
Effects of the phytochemicals, curcumin and quercetin, upon azoxymethane-induced colon cancer and 7,12-dimethylbenz[a]anthracene-induced mammary cancer in rats.
Carcinogenesis 1996;17(6):1305-11.
1996: Chung F L; Kelloff G; Steele V; Pittman B; Zang E; Jiao D; Rigotty J; Choi C I; Rivenson A
Chemopreventive efficacy of arylalkyl isothiocyanates and N-acetylcysteine for lung tumorigenesis in Fischer rats.
Cancer research 1996;56(4):772-8.
1996: Kelloff G J; Crowell J A; Hawk E T; Steele V E; Lubet R A; Boone C W; Covey J M; Doody L A; Omenn G S; Greenwald P; Hong W K; Parkinson D R; Bagheri D; Baxter G T; Blunden M; Doeltz M K; Eisenhauer K M; Johnson K; Knapp G G; Longfellow D G; Malone W F; Nayfield S G; Seifried H E; Swall L M; Sigman C C
Strategy and planning for chemopreventive drug development: clinical development plans II.
Journal of cellular biochemistry. Supplement 1996;26():54-71.
1996: Steele V E; Sharma S; Mehta R; Elmore E; Redpath L; Rudd C; Bagheri D; Sigman C C; Kelloff G J
Use of in vitro assays to predict the efficacy of chemopreventive agents in whole animals.
Journal of cellular biochemistry. Supplement 1996;26():29-53.
1996: Kelloff G J; Boone C W; Crowell J A; Steele V E; Lubet R A; Doody L A; Malone W F; Hawk E T; Sigman C C
New agents for cancer chemoprevention.
Journal of cellular biochemistry. Supplement 1996;26():1-28.
1996: Crist K A; Kim K; Goldblatt P J; Boone C W; Kelloff G J; You M
DNA quantification in cervical intraepithelial neoplasia thick tissue sections by confocal laser scanning microscopy.
Journal of cellular biochemistry. Supplement 1996;25():49-56.
1996: Liu J; Wang Y; Gu P; Patrick J; Crist K A; Sabourin C L; Stoner G D; Mitchell M F; Fanning J D; Kim K; Goldblatt P J; Kelloff G J; Boone C W; You M
Detection of genomic alterations in human cervical cancer by two-dimensional gel electrophoresis.
Journal of cellular biochemistry. Supplement 1996;25():41-8.
1996: Kelloff G J; Boone C W; Crowell J A; Nayfield S G; Hawk E; Malone W F; Steele V E; Lubet R A; Sigman C C
Risk biomarkers and current strategies for cancer chemoprevention.
Journal of cellular biochemistry. Supplement 1996;25():1-14.
1996: Kelloff G J; Boone C W; Steele V E; Crowell J A; Lubet R A; Greenwald P; Hawk E T; Fay J R; Sigman C C
Mechanistic considerations in the evaluation of chemopreventive data.
IARC scientific publications 1996;(139):203-19.
1996: Greenwald P; Kelloff G J
The role of chemoprevention in cancer control.
IARC scientific publications 1996;(139):13-22.
1995: Lubet R A; McCormick D M; Gordon G M; Grubbs C; Lei X D; Prough R A; Steele V E; Kelloff G J; Thomas C F; Moon R D
Effects of dehydroepiandrosterone on MNU-induced breast cancer in Sprague-Dawley rats.
Annals of the New York Academy of Sciences 1995;774():340-1.
1995: Greenwald P; Kelloff G J; Boone C W; McDonald S S
Genetic and cellular changes in colorectal cancer: proposed targets of chemopreventive agents.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1995;4(7):691-702.
1995: Rao C V; Rivenson A; Simi B; Zang E; Hamid R; Kelloff G J; Steele V; Reddy B S
Enhancement of experimental colon carcinogenesis by dietary 6-phenylhexyl isothiocyanate.
Cancer research 1995;55(19):4311-8.
1995: Matzinger S A; Crist K A; Stoner G D; Anderson M W; Pereira M A; Steele V E; Kelloff G J; Lubet R A; You M
K-ras mutations in lung tumors from A/J and A/J x TSG-p53 F1 mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and phenethyl isothiocyanate.
Carcinogenesis 1995;16(10):2487-92.
1995: Rao C V; Rivenson A; Kelloff G J; Reddy B S
Chemoprevention of azoxymethane-induced colon cancer by ascorbylpalmitate, carbenoxolone, dimethylfumarate and p-methoxyphenol in male F344 rats.
Anticancer research 1995;15(4):1199-204.
1995: Schatzkin A; Kelloff G
Chemo- and dietary prevention of colorectal cancer.
European journal of cancer (Oxford, England : 1990) 1995;31A(7-8):1198-204.
1995: Grubbs C J; Steele V E; Casebolt T; Juliana M M; Eto I; Whitaker L M; Dragnev K H; Kelloff G J; Lubet R L
Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol.
Anticancer research 1995;15(3):709-16.
1995: Rao C V; Rivenson A; Simi B; Zang E; Kelloff G; Steele V; Reddy B S
Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent.
Cancer research 1995;55(7):1464-72.
1995: Steele V E; Pereira M A; Sigman C C; Kelloff G J
Cancer chemoprevention agent development strategies for genistein.
The Journal of nutrition 1995;125(3 Suppl):713S-716S.
1995: Kelloff G J; Johnson J R; Crowell J A; Boone C W; DeGeorge J J; Steele V E; Mehta M U; Temeck J W; Schmidt W J; Burke G
Approaches to the development and marketing approval of drugs that prevent cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1995;4(1):1-10.
1995: Kelloff G J; Boone C W; Crowell J A; Nayfield S G; Hawk E; Steele V E; Lubet R A; Sigman C C
Strategies for phase II cancer chemoprevention trials: cervix, endometrium, and ovary.
Journal of cellular biochemistry. Supplement 1995;23():1-9.
1995: Greenwald P; Clifford C; Pilch S; Heimendinger J; Kelloff G
New directions in dietary studies in cancer: the National Cancer Institute.
Advances in experimental medicine and biology 1995;369():229-39.
1994: Lubet R A; Steele V E; Casebolt T L; Eto I; Kelloff G J; Grubbs C J
Chemopreventive effects of the aromatase inhibitors vorozole (R-83842) and 4-hydroxyandrostenedione in the methylnitrosourea (MNU)-induced mammary tumor model in Sprague-Dawley rats.
Carcinogenesis 1994;15(12):2775-80.
1994: Singh J; Kulkarni N; Kelloff G; Reddy B S
Modulation of azoxymethane-induced mutational activation of ras protooncogenes by chemopreventive agents in colon carcinogenesis.
Carcinogenesis 1994;15(7):1317-23.
1994: Moon R C; Steele V E; Kelloff G J; Thomas C F; Detrisac C J; Mehta R G; Lubet R A
Chemoprevention of MNU-induced mammary tumorigenesis by hormone response modifiers: toremifene, RU 16117, tamoxifen, aminoglutethimide and progesterone.
Anticancer research 1994;14(3A):889-93.
1994: Kelloff G J; Boone C W; Steele V E; Crowell J A; Lubet R; Sigman C C
Progress in cancer chemoprevention: perspectives on agent selection and short-term clinical intervention trials.
Cancer research 1994;54(7 Suppl):2015s-2024s.
1994: Crowell J A; Goldenthal E I; Kelloff G J; Malone W F; Boone C W
Chronic toxicity studies of the potential cancer preventive 2-(difluoromethyl)-dl-ornithine.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1994;22(3):341-54.
1994: Moon R C; Kelloff G J; Detrisac C J; Steele V E; Thomas C F; Sigman C C
Chemoprevention of OH-BBN-induced bladder cancer in mice by oltipraz, alone and in combination with 4-HPR and DFMO.
Anticancer research 1994;14(1A):5-11.
1994: Kelloff G J; Boone C W; Crowell J A; Steele V E; Lubet R; Sigman C C
Chemopreventive drug development: perspectives and progress.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1994;3(1):85-98.
1994: Boone C W; Kelloff G J
Development of surrogate endpoint biomarkers for clinical trials of cancer chemopreventive agents: relationships to fundamental properties of preinvasive (intraepithelial) neoplasia.
Journal of cellular biochemistry. Supplement 1994;19():10-22.
1994: Kelloff G J; Boone C W; Crowell J A; Steele V E; Lubet R; Doody L A
Surrogate endpoint biomarkers for phase II cancer chemoprevention trials.
Journal of cellular biochemistry. Supplement 1994;19():1-9.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: calcium.
Journal of cellular biochemistry. Supplement 1994;20():86-109.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: aspirin.
Journal of cellular biochemistry. Supplement 1994;20():74-85.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: N-Acetyl-l-cysteine.
Journal of cellular biochemistry. Supplement 1994;20():63-73.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Strategy and planning for chemopreventive drug development: clinical development plans. Chemoprevention Branch and Agent Development Committee. National Cancer Institute.
Journal of cellular biochemistry. Supplement 1994;20():55-62.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: vitamin E.
Journal of cellular biochemistry. Supplement 1994;20():282-99.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: vitamin D3 and analogs.
Journal of cellular biochemistry. Supplement 1994;20():268-81.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: tamoxifen.
Journal of cellular biochemistry. Supplement 1994;20():252-67.
1994: Kelloff G J; Johnson J R; Crowell J A; Boone C W; DeGeorge J J; Steele V E; Mehta M U; Temeck J W; Schmidt W J; Burke G
Guidance for development of chemopreventive agents.
Journal of cellular biochemistry. Supplement 1994;20():25-31.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: sulindac.
Journal of cellular biochemistry. Supplement 1994;20():240-51.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: Proscar.
Journal of cellular biochemistry. Supplement 1994;20():231-9.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: piroxicam.
Journal of cellular biochemistry. Supplement 1994;20():219-30.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: oltipraz.
Journal of cellular biochemistry. Supplement 1994;20():205-18.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: ibuprofen.
Journal of cellular biochemistry. Supplement 1994;20():197-204.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: N-(4-hydroxyphenyl)retinamide.
Journal of cellular biochemistry. Supplement 1994;20():176-96.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: 18beta-glycyrrhetinic acid.
Journal of cellular biochemistry. Supplement 1994;20():166-75.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: 2-difluoromethylornithine (DFMO).
Journal of cellular biochemistry. Supplement 1994;20():147-65.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: DHEA analog 8354.
Journal of cellular biochemistry. Supplement 1994;20():141-6.
1994: Kelloff G J; Crowell J A; Boone C W; Steele V E; Lubet R A; Greenwald P; Alberts D S; Covey J M; Doody L A; Knapp G G
Clinical development plan: beta-carotene and other carotenoids.
Journal of cellular biochemistry. Supplement 1994;20():110-140.
1994: Kelloff G J; Boone C W; Steele V E; Fay J R; Lubet R A; Crowell J A; Sigman C C
Mechanistic considerations in chemopreventive drug development.
Journal of cellular biochemistry. Supplement 1994;20():1-24.
1993: Reddy B S; Rao C V; Rivenson A; Kelloff G
Inhibitory effect of aspirin on azoxymethane-induced colon carcinogenesis in F344 rats.
Carcinogenesis 1993;14(8):1493-7.
1993: Reddy B S; Rao C V; Rivenson A; Kelloff G
Chemoprevention of colon carcinogenesis by organosulfur compounds.
Cancer research 1993;53(15):3493-8.
1993: Moon R C; Kelloff G J; Detrisac C J; Steele V E; Thomas C F; Sigman C C
Chemoprevention of OH-BBN-induced bladder cancer in mice by piroxicam.
Carcinogenesis 1993;14(7):1487-9.
1993: Rao C V; Rivenson A; Katiwalla M; Kelloff G J; Reddy B S
Chemopreventive effect of oltipraz during different stages of experimental colon carcinogenesis induced by azoxymethane in male F344 rats.
Cancer research 1993;53(11):2502-6.
1993: Singh J; Kelloff G; Reddy B S
Intermediate biomarkers of colon cancer: modulation of expression of ras oncogene by chemopreventive agents during azoxymethane induced colon carcinogenesis.
Carcinogenesis 1993;14(4):699-704.
1993: Grubbs C J; Juliana M M; Eto I; Casebolt T; Whitaker L M; Canfield G J; Manczak M; Steele V E; Kelloff G J
Chemoprevention by indomethacin of N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder tumors.
Anticancer research 1993;13(1):33-6.
1993: Boone C W; Kelloff G J
Intraepithelial neoplasia, surrogate endpoint biomarkers, and cancer chemoprevention.
Journal of cellular biochemistry. Supplement 1993;17F():37-48.
1993: Kelloff G J; Boone C W; Steele V K; Perloff M; Crowell J; Doody L A
Development of chemopreventive agents for lung and upper aerodigestive tract cancers.
Journal of cellular biochemistry. Supplement 1993;17F():2-17.
1993: Boone C W; Kelloff G J; Steele V E
Histopathology of human intraepithelial neoplasia with implications for chemoprevention strategy.
Basic life sciences 1993;61():291-300.
1993: Kelloff G J; Boone C W; Steele V E; Crowell J A; Lubet R; Doody L A; Greenwald P
Development of breast cancer chemopreventive drugs.
Journal of cellular biochemistry. Supplement 1993;17G():2-13.
1993: Boone C W; Kelloff G J; Freedman L S
Intraepithelial and postinvasive neoplasia as a stochastic continuum of clonal evolution, and its relationship to mechanisms of chemopreventive drug action.
Journal of cellular biochemistry. Supplement 1993;17G():14-25.
1992: Moon R C; Kelloff G J; Detrisac C J; Steele V E; Thomas C F; Sigman C C
Chemoprevention of MNU-induced mammary tumors in the mature rat by 4-HPR and tamoxifen.
Anticancer research 1992;12(4):1147-53.
1992: Singh J; Kelloff G; Reddy B S
Effect of chemopreventive agents on intermediate biomarkers during different stages of azoxymethane-induced colon carcinogenesis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1992;1(5):405-11.
1992: Kulkarni N; Zang E; Kelloff G; Reddy B S
Effect of the chemopreventive agents piroxicam and D,L-alpha-difluoromethylornithine on intermediate biomarkers of colon carcinogenesis.
Carcinogenesis 1992;13(6):995-1000.
1992: Reddy B S; Tokumo K; Kulkarni N; Aligia C; Kelloff G
Inhibition of colon carcinogenesis by prostaglandin synthesis inhibitors and related compounds.
Carcinogenesis 1992;13(6):1019-23.
1992: Kelloff G J; Boone C W; Malone W F; Steele V E
Chemoprevention clinical trials.
Mutation research 1992;267(2):291-5.
1992: Boone C W; Steele V E; Kelloff G J
Screening for chemopreventive (anticarcinogenic) compounds in rodents.
Mutation research 1992;267(2):251-5.
1992: Boone C W; Kelloff G J; Steele V E
Natural history of intraepithelial neoplasia in humans with implications for cancer chemoprevention strategy.
Cancer research 1992;52(7):1651-9.
1992: Boone C W; Kelloff G J; Steele V E
The natural history of intraepithelial neoplasia: relevance to the search for intermediate endpoint biomarkers.
Journal of cellular biochemistry. Supplement 1992;16G():23-6.
1992: Kelloff G J; Malone W F; Boone C W; Steele V E; Doody L A
Intermediate biomarkers of precancer and their application in chemoprevention.
Journal of cellular biochemistry. Supplement 1992;16G():15-21.
1992: Moon R C; Rao K V; Detrisac C J; Kelloff G J
Hamster lung cancer model of carcinogenesis and chemoprevention.
Advances in experimental medicine and biology 1992;320():55-61.
1992: Moon R C; Rao K V; Detrisac C J; Kelloff G J
Animal models for chemoprevention of respiratory cancer.
Journal of the National Cancer Institute. Monographs 1992;(13):45-9.
1992: Moon R C; Detrisac C J; Thomas C F; Kelloff G J
Chemoprevention of experimental bladder cancer.
Journal of cellular biochemistry. Supplement 1992;16I():134-8.
1992: Kelloff G J; Boone C W; Malone W F; Steele V E; Doody L A
Development of chemopreventive agents for bladder cancer.
Journal of cellular biochemistry. Supplement 1992;16I():1-12.
1992: Kelloff G J; Boone C W; Malone W F; Steele V E; Doody L A
Introductory remarks: development of chemopreventive agents for prostate cancer.
Journal of cellular biochemistry. Supplement 1992;16H():1-8.
1991: Rao C V; Tokumo K; Rigotty J; Zang E; Kelloff G; Reddy B S
Chemoprevention of colon carcinogenesis by dietary administration of piroxicam, alpha-difluoromethylornithine, 16 alpha-fluoro-5-androsten-17-one, and ellagic acid individually and in combination.
Cancer research 1991;51(17):4528-34.
1991: Rao C V; Tokomo K; Kelloff G; Reddy B S
Inhibition by dietary oltipraz of experimental intestinal carcinogenesis induced by azoxymethane in male F344 rats.
Carcinogenesis 1991;12(6):1051-5.
1991: Mehta R G; Steele V; Kelloff G J; Moon R C
Influence of thiols and inhibitors of prostaglandin biosynthesis on the carcinogen-induced development of mammary lesions in vitro.
Anticancer research 1991;11(2):587-91.
1991: Ratko T A; Detrisac C J; Mehta R G; Kelloff G J; Moon R C
Inhibition of rat mammary gland chemical carcinogenesis by dietary dehydroepiandrosterone or a fluorinated analogue of dehydroepiandrosterone.
Cancer research 1991;51(2):481-6.
1990: Kelloff G J; Malone W F; Boone C W; Sigman C C; Fay J R
Progress in applied chemoprevention research.
Seminars in oncology 1990;17(4):438-55.
1990: Reddy B S; Nayini J; Tokumo K; Rigotty J; Zang E; Kelloff G
Chemoprevention of colon carcinogenesis by concurrent administration of piroxicam, a nonsteroidal antiinflammatory drug with D,L-alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor, in diet.
Cancer research 1990;50(9):2562-8.
1990: Boone C W; Kelloff G J; Malone W E
Identification of candidate cancer chemopreventive agents and their evaluation in animal models and human clinical trials: a review.
Cancer research 1990;50(1):2-9.
1990: Ratko T A; Detrisac C J; Rao K V; Thomas C F; Kelloff G J; Moon R C
Interspecies analysis of the chemopreventive efficacy of dietary alpha-difluoromethylornithine.
Anticancer research 1990;10(1):67-72.
1989: Ratko T A; Detrisac C J; Dinger N M; Thomas C F; Kelloff G J; Moon R C
Chemopreventive efficacy of combined retinoid and tamoxifen treatment following surgical excision of a primary mammary cancer in female rats.
Cancer research 1989;49(16):4472-6.
1989: Greenwald P; Cullen J W; Kelloff G; Pierson H F
Chemoprevention of lung cancer. Problems and progress.
Chest 1989;96(1 Suppl):14S-17S.
1987: Reddy B S; Maruyama H; Kelloff G
Dose-related inhibition of colon carcinogenesis by dietary piroxicam, a nonsteroidal antiinflammatory drug, during different stages of rat colon tumor development.
Cancer research 1987;47(20):5340-6.

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