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Darren Kelly

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K A Connelly; A Advani; S Advani; Darren J Kelly; H Krum; K Thai; S Thomas; Yuan Zhang; Richard E Gilbert
Combination angiotensin converting enzyme and direct renin inhibition in heart failure following experimental myocardial infarction.
Mathew J Jenkins; Darren J Kelly; James T Pearson; Daryl O Schwenke; Amanda J Edgley; Yutaka Fujii; Hatsue Ishibashi-Ueda; Takashi Sonobe; Naoto Yagi; Mikiyasu Shirai
Myosin heads are displaced from actin filaments in the in situ beating rat heart in early diabetes.
Robyn G Langham; Darren J Kelly
Urotensin II and the kidney.

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2013: K A Connelly; A Advani; S Advani; Darren J Kelly; H Krum; K Thai; S Thomas; Yuan Zhang; Richard E Gilbert
Combination angiotensin converting enzyme and direct renin inhibition in heart failure following experimental myocardial infarction.
Cardiovascular therapeutics 2013;31(2):84-91.
2013: Mathew J Jenkins; Darren J Kelly; James T Pearson; Daryl O Schwenke; Amanda J Edgley; Yutaka Fujii; Hatsue Ishibashi-Ueda; Takashi Sonobe; Naoto Yagi; Mikiyasu Shirai
Myosin heads are displaced from actin filaments in the in situ beating rat heart in early diabetes.
Biophysical journal 2013;104(5):1065-72.
2013: Robyn G Langham; Darren J Kelly
Urotensin II and the kidney.
Current opinion in nephrology and hypertension 2013;22(1):107-12.
2012: Suree Lekawanvijit; Bing H Wang; Darren J Kelly; Andrew R Kompa; Henry Krum
Cardiorenal syndrome: the emerging role of protein-bound uremic toxins.
Circulation research 2012;111(11):1470-83.
2012: Darren A Yuen; Yanling Zhang; Lei Zhu; Suzanne L Advani; Kim A Connelly; Alison J Cox; Ian W Gibson; Raymond C Harris; M Golam Kabir; Darren J Kelly; Bailey E Stead; Takamune Takahashi; Tomoko Takano; Kerri Thai; Kathryn E White; Andrew Advani
eNOS deficiency predisposes podocytes to injury in diabetes.
Journal of the American Society of Nephrology : JASN 2012;23(11):1810-23.
2012: Shan Liu; Bing H Wang; Darren J Kelly; Andrew R Kompa; Suree Lekawanvijit; Henry Krum
Cardiorenal syndrome: pathophysiology, preclinical models, management and potential role of uraemic toxins.
Clinical and experimental pharmacology & physiology 2012;39(8):692-700.
2012: Yuan Zhang; Alison J Cox; Amanda J Edgley; Richard E Gilbert; Andrew R Kompa; Henry Krum; Andrew K Powell; David I Stapleton; Bing Wang; Spencer J Williams; Steven C Zammit; Darren J Kelly
FT011, a new anti-fibrotic drug, attenuates fibrosis and chronic heart failure in experimental diabetic cardiomyopathy.
European journal of heart failure 2012;14(5):549-62.
2012: Suree Lekawanvijit; Bing H Wang; Yuan Zhang; Darren J Kelly; Andrew R Kompa; Henry Krum
Myocardial infarction impairs renal function, induces renal interstitial fibrosis, and increases renal KIM-1 expression: implications for cardiorenal syndrome.
American journal of physiology. Heart and circulatory physiology 2012;302(9):H1884-93.
2012: Amanda J Edgley; Henry Krum; Darren J Kelly
Targeting fibrosis for the treatment of heart failure: a role for transforming growth factor-β.
Cardiovascular therapeutics 2012;30(1):e30-40.
2012: Duncan J Campbell; Alicia J Jenkins; Mary Jane Black; James F Kenny; Andrew E Newcomb; David L Prior; Casper G Schalkwijk; Jithendra B Somaratne; Michael Yii; Darren J Kelly
Diastolic dysfunction of aging is independent of myocardial structure but associated with plasma advanced glycation end-product levels.
PloS one 2012;7(11):e49813.
2012: Richard E Gilbert; Alison J Cox; Henry Krum; Robyn Langham; David I Stapleton; Spencer J Williams; Steven C Zammit; Yuan Zhang; Darren J Kelly
A purpose-synthesised anti-fibrotic agent attenuates experimental kidney diseases in the rat.
PloS one 2012;7(10):e47160.
2012: Suree Lekawanvijit; Minako Manabe; Fuyuhiko Nishijima; Bing H Wang; Darren J Kelly; Andrew R Kompa; Robyn G Langham; Henry Krum
Chronic kidney disease-induced cardiac fibrosis is ameliorated by reducing circulating levels of a non-dialysable uremic toxin, indoxyl sulfate.
PloS one 2012;7(7):e41281.
2011: Hirobumi Tokuyama; Yuan Zhang; Alison J Cox; Renae M Gow; Darren J Kelly; Sandra Kim; Robyn G Langham; Richard E Gilbert
Protein kinase C β inhibition ameliorates experimental mesangial proliferative glomerulonephritis.
Nephrology (Carlton, Vic.) 2011;16(7):649-55.
2011: Andrew Advani; Alison J Cox; Richard E Gilbert; Kathryn J Wiggins; Yuan Zhang; Darren J Kelly
Inhibition of the epidermal growth factor receptor preserves podocytes and attenuates albuminuria in experimental diabetic nephropathy.
Nephrology (Carlton, Vic.) 2011;16(6):573-81.
2011: Dennis H Lau; Peter J Psaltis; Angelo Carbone; Darren J Kelly; Lorraine Mackenzie; Michael Worthington; Robert G Metcalf; Pawel Kuklik; Adam J Nelson; Yuan Zhang; Christopher X Wong; Anthony G Brooks; David A Saint; Michael J James; James Edwards; Glenn D Young; Stephen G Worthley; Prashanthan Sanders
Atrial protective effects of n-3 polyunsaturated fatty acids: a long-term study in ovine chronic heart failure.
Heart rhythm : the official journal of the Heart Rhythm Society 2011;8(4):575-82.
2011: Duncan J Campbell; Jithendra B Somaratne; Alicia J Jenkins; David L Prior; Michael Yii; James F Kenny; Andrew E Newcomb; Darren J Kelly; Mary Jane Black
Differences in myocardial structure and coronary microvasculature between men and women with coronary artery disease.
Hypertension 2011;57(2):186-92.
2011: Dennis H Lau; Peter J Psaltis; Lorraine Mackenzie; Darren J Kelly; Angelo Carbone; Michael Worthington; Adam J Nelson; Yuan Zhang; Pawel Kuklik; Christopher X Wong; James Edwards; David A Saint; Stephen G Worthley; Prashanthan Sanders
Atrial remodeling in an ovine model of anthracycline-induced nonischemic cardiomyopathy: remodeling of the same sort.
Journal of cardiovascular electrophysiology 2011;22(2):175-82.
2011: Fay Lin Khong; Henry Krum; Weier Qi; Owen Woodman; Yuan Zhang; Kim Connelly; Amanda J Edgley; Darren J Kelly
3',4'-Dihydroxyflavonol antioxidant attenuates diastolic dysfunction and cardiac remodeling in streptozotocin-induced diabetic m(Ren2)27 rats.
PloS one 2011;6(7):e22777.
2010: Andrew R Kompa; Bing H Wang; Arintaya Phrommintikul; Pei Y Ho; Darren J Kelly; David J Behm; Stephen A Douglas; Henry Krum
Chronic urotensin II receptor antagonist treatment does not alter hypertrophy or fibrosis in a rat model of pressure-overload hypertrophy.
Peptides 2010;31(8):1523-30.
2010: Suree Lekawanvijit; Anastasia Adrahtas; Darren J Kelly; Andrew R Kompa; Bing H Wang; Henry Krum
Does indoxyl sulfate, a uraemic toxin, have direct effects on cardiac fibroblasts and myocytes?
European heart journal 2010;31(14):1771-9.
2010: Sih Min Tan; Yuan Zhang; Kim Connelly; Richard E Gilbert; Darren J Kelly
Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarction.
American journal of physiology. Heart and circulatory physiology 2010;298(5):H1415-25.
2010: Amanda J Edgley; Renae M Gow; Darren J Kelly
Laser-capture microdissection and pressure catapulting for the analysis of gene expression in the renal glomerulus.
Methods in molecular biology (Clifton, N.J.) 2010;611():29-40.
2009: Steven C Zammit; Alison J Cox; Renae M Gow; Yuan Zhang; Richard E Gilbert; Henry Krum; Darren J Kelly; Spencer J Williams
Evaluation and optimization of antifibrotic activity of cinnamoyl anthranilates.
Bioorganic & medicinal chemistry letters 2009;19(24):7003-6.
2009: Weier Qi; Xinming Chen; John Holian; Christina Y R Tan; Darren J Kelly; Carol A Pollock
Transcription factors Krüppel-like factor 6 and peroxisome proliferator-activated receptor-{gamma} mediate high glucose-induced thioredoxin-interacting protein.
The American journal of pathology 2009;175(5):1858-67.
2009: Kathryn J Wiggins; Darren J Kelly
Aliskiren: a novel renoprotective agent or simply an alternative to ACE inhibitors?
Kidney international 2009;76(1):23-31.
2009: Darren J Kelly; Amanda J Edgley; Yuan Zhang; Keng-Ee Thai; Sih Min Tan; Alison J Cox; Andrew Advani; Kim Connelly; Catharine I Whiteside; Richard E Gilbert
Protein kinase C-beta inhibition attenuates the progression of nephropathy in non-diabetic kidney disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(6):1782-90.
2009: Kathryn J Wiggins; Renae M Gow; John Kanellis; Prue Hill; Darren J Kelly; Alison Skene; DJ Goodman; Robyn G Langham
BK virus RNA can be detected in archival renal transplant biopsies using the reverse trancription polymerase chain reaction.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(2):661-6.
2008: Chrishan S Samuel; Tim D Hewitson; Yuan Zhang; Darren J Kelly
Relaxin ameliorates fibrosis in experimental diabetic cardiomyopathy.
Endocrinology 2008;149(7):3286-93.
2008: Robyn G Langham; Darren J Kelly; R M Gow; Y Zhang; Alison J Cox; W Qi; K Thai; C A Pollock; P K Christensen; H-H Parving; Richard E Gilbert
Increased renal gene transcription of protein kinase C-beta in human diabetic nephropathy: relationship to long-term glycaemic control.
Diabetologia 2008;51(4):668-74.
2008: Arintaya Phrommintikul; Lavinia Tran; Andrew R Kompa; Bing Wang; Anastasia Adrahtas; Danielle Cantwell; Darren J Kelly; Henry Krum
Effects of a Rho kinase inhibitor on pressure overload induced cardiac hypertrophy and associated diastolic dysfunction.
American journal of physiology. Heart and circulatory physiology 2008;294(4):H1804-14.
2008: Hirobumi Tokuyama; Darren J Kelly; Alison Cox; Yuan Zhang; Kerri Thai; David J Nikolic-Paterson; Richard E Gilbert
Tranilast ameliorates experimental mesangial proliferative glomerulonephritis.
Nephron. Experimental nephrology 2008;109(1):e1-7.
2007: Darren J Kelly; Y Zhang; G Moe; George Naik; Richard E Gilbert
Aliskiren, a novel renin inhibitor, is renoprotective in a model of advanced diabetic nephropathy in rats.
Diabetologia 2007;50(11):2398-404.
2007: Darren J Kelly; Yuan Zhang; Kim Connelly; Alison J Cox; Jennifer Martin; Henry Krum; Richard E Gilbert
Tranilast attenuates diastolic dysfunction and structural injury in experimental diabetic cardiomyopathy.
American journal of physiology. Heart and circulatory physiology 2007;293(5):H2860-9.
2007: Kim Connelly; Darren J Kelly; Yuan Zhang; David L Prior; Jennifer Martin; Alison J Cox; K Thai; M P Feneley; james/jim Tsoporis; K E White; Henry Krum; Richard E Gilbert
Functional, structural and molecular aspects of diastolic heart failure in the diabetic (mRen-2)27 rat.
Cardiovascular research 2007;76(2):280-91.
2007: Andrew Advani; Darren J Kelly; Suzanne L Advani; Alison J Cox; Kerri Thai; Yuan Zhang; Kathryn E White; Renae M Gow; Sally M Marshall; Brent M Steer; Philip A Marsden; P Elizabeth Rakoczy; Richard E Gilbert
Role of VEGF in maintaining renal structure and function under normotensive and hypertensive conditions.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(36):14448-53.
2007: Richard E Gilbert; Sandra A Kim; Katherine R Tuttle; George L Bakris; Robert D Toto; Janet B McGill; Douglas J Haney; Darren J Kelly; Pamela W Anderson
Effect of ruboxistaurin on urinary transforming growth factor-beta in patients with diabetic nephropathy and type 2 diabetes.
Diabetes care 2007;30(4):995-6.
2007: Robyn G Langham; Darren J Kelly
Diabetic nephropathy without the diabetes: if not hyperglycaemia, then what?
Nephrology (Carlton, Vic.) 2007;12(1):67-8.
2007: Kim Connelly; Andrew Boyle; Darren J Kelly
Angiotensin II and the cardiac complications of diabetes mellitus.
Current pharmaceutical design 2007;13(26):2721-9.
2007: Hirobumi Tokuyama; Darren J Kelly; Yuan Zhang; Renae M Gow; Richard E Gilbert
Macrophage infiltration and cellular proliferation in the non-ischemic kidney and heart following prolonged unilateral renal ischemia.
Nephron. Physiology 2007;106(3):p54-62.
2006: Robyn G Langham; Darren J Kelly; Renae M Gow; Yuan Zhang; Daniel Cordonnier; Nicole Pinel; Philippe Zaoui; Richard E Gilbert
Transforming growth factor-beta in human diabetic nephropathy: effects of ACE inhibition.
Diabetes care 2006;29(12):2670-5.
2006: Darren J Kelly; Yuan Zhang; Alison J Cox; Richard E Gilbert
Combination therapy with tranilast and angiotensin-converting enzyme inhibition provides additional renoprotection in the remnant kidney model.
Kidney international 2006;69(11):1954-60.
2006: Jennifer L Wilkinson-Berka; Daria Jones; George Taylor; Kassie Jaworski; Darren J Kelly; Steve B Ludbrook; Robert N Willette; Sanjay Kumar; Richard E Gilbert
SB-267268, a nonpeptidic antagonist of alpha(v)beta3 and alpha(v)beta5 integrins, reduces angiogenesis and VEGF expression in a mouse model of retinopathy of prematurity.
Investigative ophthalmology & visual science 2006;47(4):1600-5.
2006: Kim Connelly; D L Prior; Darren J Kelly; M P Feneley; Henry Krum; Richard E Gilbert
Load-sensitive measures may overestimate global systolic function in the presence of left ventricular hypertrophy: a comparison with load-insensitive measures.
American journal of physiology. Heart and circulatory physiology 2006;290(4):H1699-705.
2006: Richard E Gilbert; Kim Connelly; Darren J Kelly; Carol A Pollock; Henry Krum
Heart failure and nephropathy: catastrophic and interrelated complications of diabetes.
Clinical journal of the American Society of Nephrology : CJASN 2006;1(2):193-208.
2005: Andrew Boyle; Darren J Kelly; Yuan Zhang; Alison J Cox; Renae M Gow; Kerrie Way; Silviu Itescu; Henry Krum; Richard E Gilbert
Inhibition of protein kinase C reduces left ventricular fibrosis and dysfunction following myocardial infarction.
Journal of molecular and cellular cardiology 2005;39(2):213-21.
2005: Darren J Kelly; Anna Chanty; Renae M Gow; Yuan Zhang; Richard E Gilbert
Protein kinase Cbeta inhibition attenuates osteopontin expression, macrophage recruitment, and tubulointerstitial injury in advanced experimental diabetic nephropathy.
Journal of the American Society of Nephrology : JASN 2005;16(6):1654-60.
2005: Darren J Kelly; Yuan Zhang; Renae M Gow; Silviu Itescu; Richard E Gilbert
Cells expressing the stem cell factor receptor, c-kit, contribute to neoangiogenesis in diabetes.
Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease 2005;2(2):76-80.
2005: Jennifer Martin; Darren J Kelly; Sally A Mifsud; Yuan Zhang; Alison J Cox; Fiona See; Henry Krum; Jennifer L Wilkinson-Berka; Richard E Gilbert
Tranilast attenuates cardiac matrix deposition in experimental diabetes: role of transforming growth factor-beta.
Cardiovascular research 2005;65(3):694-701.
2004: Lesley Wassef; Darren J Kelly; Richard E Gilbert
Epidermal growth factor receptor inhibition attenuates early kidney enlargement in experimental diabetes.
Kidney international 2004;66(5):1805-14.
2004: Robyn G Langham; Darren J Kelly; Renae M Gow; Yuan Zhang; John K Dowling; Napier M Thomson; Richard E Gilbert
Increased expression of urotensin II and urotensin II receptor in human diabetic nephropathy.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2004;44(5):826-31.
2004: Darren J Kelly; Yuan Zhang; Renae M Gow; Richard E Gilbert
Tranilast attenuates structural and functional aspects of renal injury in the remnant kidney model.
Journal of the American Society of Nephrology : JASN 2004;15(10):2619-29.
2004: Darren J Kelly; Alison J Cox; Renae M Gow; Yuan Zhang; Bruce E Kemp; Richard E Gilbert
Platelet-derived growth factor receptor transactivation mediates the trophic effects of angiotensin II in vivo.
Hypertension 2004;44(2):195-202.
2004: Kristy L Edgtton; Renae M Gow; Darren J Kelly; Peter Carmeliet; A Richard Kitching
Plasmin is not protective in experimental renal interstitial fibrosis.
Kidney international 2004;66(1):68-76.
2004: Jennifer L Wilkinson-Berka; Sanja Babic; Tanyth E De Gooyer; Alan Stitt; Kassie Jaworski; Leslie G T Ong; Darren J Kelly; Richard E Gilbert
Inhibition of platelet-derived growth factor promotes pericyte loss and angiogenesis in ischemic retinopathy.
The American journal of pathology 2004;164(4):1263-73.
2004: Darren J Kelly; Alicia N Stein-Oakley; Yuan Zhang; Lesley Wassef; Julie Maguire; Takehiko Koji; Napier Thomson; Jennifer L Wilkinson-Berka; Richard E Gilbert
Fas-induced apoptosis is a feature of progressive diabetic nephropathy in transgenic (mRen-2)27 rats: attenuation with renin-angiotensin blockade.
Nephrology (Carlton, Vic.) 2004;9(1):7-13.
2004: Tanyth E De Gooyer; Sandford L Skinner; Mary E Wlodek; Darren J Kelly; Jennifer L Wilkinson-Berka
Angiotensin II influences ovarian follicle development in the transgenic (mRen-2)27 and Sprague-Dawley rat.
The Journal of endocrinology 2004;180(2):311-24.
2004: Lesley Wassef; Robyn G Langham; Darren J Kelly
Vasoactive renal factors and the progression of diabetic nephropathy.
Current pharmaceutical design 2004;10(27):3373-84.
2004: Robyn G Langham; Darren J Kelly; Alison J Cox; Renae M Gow; Harry Holthofer; Richard E Gilbert
Angiotensin II-induced proteinuria and expression of the podocyte slit pore membrane protein, nephrin.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(1):262-3.
2003: Geoffrey Boner; Alison J Cox; Darren J Kelly; Ana Tobar; Joëlle Bernheim; Robyn G Langham; Mark E Cooper; Richard E Gilbert
Does vascular endothelial growth factor (VEGF) play a role in the pathogenesis of minimal change disease?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(11):2293-9.
2003: F Bonnet; Z Cao; M E Cooper; Alison J Cox; Darren J Kelly; Richard E Gilbert
Tranilast attenuates vascular hypertrophy, matrix accumulation and growth factor overexpression in experimental diabetes.
Diabetes & metabolism 2003;29(4 Pt 1):386-92.
2003: Susan E Jones; Darren J Kelly; Alison J Cox; Yuan Zhang; Renae M Gow; Richard E Gilbert
Mast cell infiltration and chemokine expression in progressive renal disease.
Kidney international 2003;64(3):906-13.
2003: Robyn G Langham; Darren J Kelly; Julie Maguire; John P Dowling; Richard E Gilbert; Napier M Thomson
Over-expression of platelet-derived growth factor in human diabetic nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(7):1392-6.
2003: Darren J Kelly; Claire Hepper; Leonard L Wu; Alison J Cox; Richard E Gilbert
Vascular endothelial growth factor expression and glomerular endothelial cell loss in the remnant kidney model.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(7):1286-92.
2003: Jennifer L Wilkinson-Berka; Nicole S Alousis; Darren J Kelly; Richard E Gilbert
COX-2 inhibition and retinal angiogenesis in a mouse model of retinopathy of prematurity.
Investigative ophthalmology & visual science 2003;44(3):974-9.
2003: Darren J Kelly; Yuan Zhang; Claire Hepper; Renae M Gow; Kassie Jaworski; Bruce E Kemp; Jennifer L Wilkinson-Berka; Richard E Gilbert
Protein kinase C beta inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension.
Diabetes 2003;52(2):512-8.
2003: Sally A Mifsud; Darren J Kelly; Weier Qi; Yuan Zhang; Carol A Pollock; Jennifer L Wilkinson-Berka; Richard E Gilbert
Intervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathy.
Nephron. Physiology 2003;95(4):p83-91.
2003: Christina Moravski; Sandford L Skinner; Anthony J Stubbs; Stella Sarlos; Darren J Kelly; Mark E Cooper; Richard E Gilbert; Jennifer L Wilkinson-Berka
The renin-angiotensin system influences ocular endothelial cell proliferation in diabetes: transgenic and interventional studies.
The American journal of pathology 2003;162(1):151-60.
2002: Robyn G Langham; Darren J Kelly; Alison J Cox; Napier M Thomson; Harry Holthöfer; Philippe Zaoui; Nicole Pinel; Daniel Cordonnier; Richard E Gilbert
Proteinuria and the expression of the podocyte slit diaphragm protein, nephrin, in diabetic nephropathy: effects of angiotensin converting enzyme inhibition.
Diabetologia 2002;45(11):1572-6.
2002: Jennifer L Wilkinson-Berka; Darren J Kelly; Suzanne M Koerner; Kassie Jaworski; Belinda Davis; Vicki Thallas; Mark E Cooper
ALT-946 and aminoguanidine, inhibitors of advanced glycation, improve severe nephropathy in the diabetic transgenic (mREN-2)27 rat.
Diabetes 2002;51(11):3283-9.
2002: Maria L Macheda; Darren J Kelly; James D Best; Suzanne Rogers
Expression during rat fetal development of GLUT12--a member of the class III hexose transporter family.
Anatomy and embryology 2002;205(5-6):441-52.
2002: Jennifer L Wilkinson-Berka; Darren J Kelly; Pei Rong; Duncan J Campbell; Sandford L Skinner
Characterisation of a thymic renin-angiotensin system in the transgenic m(Ren-2)27 rat.
Molecular and cellular endocrinology 2002;194(1-2):201-9.
2002: Darren J Kelly; Petri Aaltonen; Alison J Cox; Jon R Rumble; Robyn G Langham; Sianna Panagiotopoulos; George Jerums; Harry Holthöfer; Richard E Gilbert
Expression of the slit-diaphragm protein, nephrin, in experimental diabetic nephropathy: differing effects of anti-proteinuric therapies.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(7):1327-32.
2002: Darren J Kelly; Jennifer L Wilkinson-Berka; Sharon D Ricardo; Alison J Cox; Richard E Gilbert
Progression of tubulointerstitial injury by osteopontin-induced macrophage recruitment in advanced diabetic nephropathy of transgenic (mRen-2)27 rats.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(6):985-91.
2002: Sally A Mifsud; Sandford L Skinner; Mark E Cooper; Darren J Kelly; Jennifer L Wilkinson-Berka
Effects of low-dose and early versus late perindopril treatment on the progression of severe diabetic nephropathy in (mREN-2)27 rats.
Journal of the American Society of Nephrology : JASN 2002;13(3):684-92.
2002: Darren J Kelly; Alison J Cox; Mary Tolcos; Mark E Cooper; Jennifer L Wilkinson-Berka; Richard E Gilbert
Attenuation of tubular apoptosis by blockade of the renin-angiotensin system in diabetic Ren-2 rats.
Kidney international 2002;61(1):31-9.
2001: Jennifer L Wilkinson-Berka; Darren J Kelly; Richard E Gilbert
The interaction between the renin-angiotensin system and vascular endothelial growth factor in the pathogenesis of retinal neovascularization in diabetes.
Journal of vascular research 2001;38(6):527-35.
2001: Darren J Kelly; Richard E Gilbert; Alison J Cox; T Soulis; George Jerums; Mark E Cooper
Aminoguanidine ameliorates overexpression of prosclerotic growth factors and collagen deposition in experimental diabetic nephropathy.
Journal of the American Society of Nephrology : JASN 2001;12(10):2098-107.
2001: Georgina Paizis; Richard E Gilbert; Mark E Cooper; Padma Murthi; Josefa M Schembri; L L Wu; Jon R Rumble; Darren J Kelly; Chris Tikellis; Alison Cox; Richard A Smallwood; Peter W Angus
Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis.
Journal of hepatology 2001;35(3):376-85.
2001: Sally A Mifsud; Terri J Allen; John F Bertram; UL Hulthen; Darren J Kelly; Mark E Cooper; Jennifer L Wilkinson-Berka; Richard E Gilbert
Podocyte foot process broadening in experimental diabetic nephropathy: amelioration with renin-angiotensin blockade.
Diabetologia 2001;44(7):878-82.
2001: Jennifer L Wilkinson-Berka; N J Gibbs; Mark E Cooper; Sandford L Skinner; Darren J Kelly
Renoprotective and anti-hypertensive effects of combined valsartan and perindopril in progressive diabetic nephropathy in the transgenic (mRen-2)27 rat.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2001;16(7):1343-9.
2001: Richard E Gilbert; Darren J Kelly; R C Atkins
Novel approaches to the treatment of progressive renal disease.
Current opinion in pharmacology 2001;1(2):183-9.
2001: Richard E Gilbert; Darren J Kelly; T McKay; S Chadban; Prudence A Hill; Mark E Cooper; R C Atkins; David J Nikolic-Paterson
PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis.
Kidney international 2001;59(4):1324-32.
2001: R E Gilbert; Jennifer L Wilkinson-Berka; Darren J Kelly
Angiotensin and renal fibrosis.
Contributions to nephrology 2001;(135):171-86.
2000: Christina Moravski; Darren J Kelly; Mark E Cooper; Richard E Gilbert; John F Bertram; S Shahinfar; Sandford L Skinner; Jennifer L Wilkinson-Berka
Retinal neovascularization is prevented by blockade of the renin-angiotensin system.
Hypertension 2000;36(6):1099-104.
2000: Zemin Cao; Darren J Kelly; Alison Cox; David Casley; Josephine M Forbes; Paul Martinello; R Dean; Richard E Gilbert; Mark E Cooper
Angiotensin type 2 receptor is expressed in the adult rat kidney and promotes cellular proliferation and apoptosis.
Kidney international 2000;58(6):2437-51.
2000: Richard E Gilbert; Darren J Kelly; Alison J Cox; Jennifer L Wilkinson-Berka; Jon R Rumble; Tanya M Osicka; Sianna Panagiotopoulos; V Lee; EC Hendrich; George Jerums; Mark E Cooper
Angiotensin converting enzyme inhibition reduces retinal overexpression of vascular endothelial growth factor and hyperpermeability in experimental diabetes.
Diabetologia 2000;43(11):1360-7.
2000: Zemin Cao; Mark E Cooper; L L Wu; Alison J Cox; Karin A Jandeleit-Dahm; Darren J Kelly; Richard E Gilbert
Blockade of the renin-angiotensin and endothelin systems on progressive renal injury.
Hypertension 2000;36(4):561-8.
2000: Darren J Kelly; Sandford L Skinner; Richard E Gilbert; Alison J Cox; Mark E Cooper; Jennifer L Wilkinson-Berka
Effects of endothelin or angiotensin II receptor blockade on diabetes in the transgenic (mRen-2)27 rat.
Kidney international 2000;57(5):1882-94.
2000: Richard E Gilbert; Jon R Rumble; Zemin Cao; Alison J Cox; Pauline van Eeden; Terri J Allen; Darren J Kelly; Mark E Cooper
Endothelin receptor antagonism ameliorates mast cell infiltration, vascular hypertrophy, and epidermal growth factor expression in experimental diabetes.
Circulation research 2000;86(2):158-65.
2000: Karin A Jandeleit-Dahm; Jon R Rumble; Alison J Cox; Darren J Kelly; Marie A Dziadek; Mark E Cooper; Richard E Gilbert
SPARC gene expression is increased in diabetes-related mesenteric vascular hypertrophy.
Microvascular research 2000;59(1):61-71.
1999: Mark E Cooper; D Vranes; S Youssef; Steven A Stacker; Alison J Cox; Bishoy Rizkalla; David Casley; Leon A Bach; Darren J Kelly; Richard E Gilbert
Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes.
Diabetes 1999;48(11):2229-39.
1999: Richard E Gilbert; L L Wu; Darren J Kelly; A Cox; Jennifer L Wilkinson-Berka; Colin I Johnston; Mark E Cooper
Pathological expression of renin and angiotensin II in the renal tubule after subtotal nephrectomy. Implications for the pathogenesis of tubulointerstitial fibrosis.
The American journal of pathology 1999;155(2):429-40.
1999: D J Campbell; Darren J Kelly; Jennifer L Wilkinson-Berka; Mark E Cooper; Sandford L Skinner
Increased bradykinin and "normal" angiotensin peptide levels in diabetic Sprague-Dawley and transgenic (mRen-2)27 rats.
Kidney international 1999;56(1):211-21.
1999: Richard E Gilbert; Alison J Cox; Darren J Kelly; Jennifer L Wilkinson-Berka; E H Sage; George Jerums; Mark E Cooper
Localization of secreted protein acidic and rich in cysteine (SPARC) expression in the rat eye.
Connective tissue research 1999;40(4):295-303.
1998: Richard E Gilbert; Jennifer L Wilkinson-Berka; D W Johnson; Alison Cox; T Soulis; LL Wu; Darren J Kelly; George Jerums; Carol A Pollock; Mark E Cooper
Renal expression of transforming growth factor-beta inducible gene-h3 (beta ig-h3) in normal and diabetic rats.
Kidney international 1998;54(4):1052-62.
1998: Richard E Gilbert; D Vranes; J L Berka; Darren J Kelly; A Cox; L L Wu; Steven A Stacker; Mark E Cooper
Vascular endothelial growth factor and its receptors in control and diabetic rat eyes.
Laboratory investigation; a journal of technical methods and pathology 1998;78(8):1017-27.
1998: Darren J Kelly; Jennifer L Wilkinson-Berka; Terri J Allen; Mark E Cooper; Sandford L Skinner
A new model of diabetic nephropathy with progressive renal impairment in the transgenic (mRen-2)27 rat (TGR).
Kidney international 1998;54(2):343-52.
1996: J L Berka; Darren J Kelly; D B Robinson; Daine Alcorn; Philip D Marley; R T Fernley; Sandford L Skinner
Adrenaline cells of the rat adrenal cortex and medulla contain renin and prorenin.
Molecular and cellular endocrinology 1996;119(2):175-84.
1994: Pei Rong; J L Berka; Darren J Kelly; Daine Alcorn; Sandford L Skinner
Renin processing and secretion in adrenal and retina of transgenic (mREN-2)27 rats.
Kidney international 1994;46(6):1583-7.