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Priscilla Kelly

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Priscilla N Kelly; Jerry M Adams; A R D Delbridge; S Grabow; Andreas Strasser
Prophylactic treatment with the BH3 mimetic ABT-737 impedes Myc-driven lymphomagenesis in mice.
S Grabow; L Happo; Priscilla N Kelly; K D Mason; M Cook; P Waring; Andreas Strasser
Pharmacological blockade of Bcl-2, Bcl-x(L) and Bcl-w by the BH3 mimetic ABT-737 has only minor impact on tumour development in p53-deficient mice.
Priscilla N Kelly; Aleksandar Dakic; Jerry M Adams; Stephen L Nutt; Andreas Strasser
Tumor growth need not be driven by rare cancer stem cells.

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2013: Priscilla N Kelly; Jerry M Adams; A R D Delbridge; S Grabow; Andreas Strasser
Prophylactic treatment with the BH3 mimetic ABT-737 impedes Myc-driven lymphomagenesis in mice.
Cell death and differentiation 2013;20(1):57-63.
2012: S Grabow; L Happo; Priscilla N Kelly; K D Mason; M Cook; P Waring; Andreas Strasser
Pharmacological blockade of Bcl-2, Bcl-x(L) and Bcl-w by the BH3 mimetic ABT-737 has only minor impact on tumour development in p53-deficient mice.
Cell death and differentiation 2012;19(4):623-32.
2007: Priscilla N Kelly; Aleksandar Dakic; Jerry M Adams; Stephen L Nutt; Andreas Strasser
Tumor growth need not be driven by rare cancer stem cells.
Science (New York, N.Y.) 2007;317(5836):337.
2007: Hamsa Puthalakath; Lorraine A O'Reilly; Priscilla Gunn; Lily Lee; Priscilla N Kelly; Nicholas D Huntington; Peter D Hughes; Ewa M Michalak; Jennifer L McKimm-Breschkin; Noburo Motoyama; Tomomi Gotoh; Shizuo Akira; Philippe Bouillet; Andreas Strasser
ER stress triggers apoptosis by activating BH3-only protein Bim.
Cell 2007;129(7):1337-49.
2007: Priscilla N Kelly; Hamsa Puthalakath; Jerry M Adams; Andreas Strasser
Endogenous bcl-2 is not required for the development of Emu-myc-induced B-cell lymphoma.
Blood 2007;109(11):4907-13.
2007: Kylie D Mason; Marina R Carpinelli; Jamie I Fletcher; Janelle E Collinge; Adrienne A Hilton; Sarah Ellis; Priscilla N Kelly; Paul G Ekert; Donald Metcalf; Andrew W Roberts; David C S Huang; Benjamin T Kile
Programmed anuclear cell death delimits platelet life span.
Cell 2007;128(6):1173-86.
2006: Junya Kuroda; Hamsa Puthalakath; Mark Cragg; Priscilla N Kelly; Philippe Bouillet; David C S Huang; Shinya Kimura; Oliver G Ottmann; Brian J Druker; Andreas Villunger; Andrew W Roberts; Andreas Strasser
Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(40):14907-12.
2006: Paul G Ekert; Anissa M Jabbour; Anand Manoharan; Jacki E Heraud; Jai Yu; Miha Pakusch; Ewa M Michalak; Priscilla N Kelly; Bernard A Callus; Thomas Kiefer; Anne Verhagen; John Silke; Andreas Strasser; Christoph Borner; David L Vaux
Cell death provoked by loss of interleukin-3 signaling is independent of Bad, Bim, and PI3 kinase, but depends in part on Puma.
Blood 2006;108(5):1461-8.
2005: Miriam Erlacher; Ewa M Michalak; Priscilla N Kelly; Verena Labi; Harald Niederegger; Leigh Coultas; Jerry M Adams; Andreas Strasser; Andreas Villunger
BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo.
Blood 2005;106(13):4131-8.
2005: Jerry M Adams; David C S Huang; Andreas Strasser; S Willis; Lin Chen; Andrew Wei; Mark F Van Delft; Jamie I Fletcher; Hamsa Puthalakath; Junya Kuroda; Ewa M Michalak; Priscilla N Kelly; Philippe Bouillet; Andreas Villunger; Lorraine A O'Reilly; Mary L Bath; Darrin P Smith; Alexander Egle; Alan W Harris; Mark G Hinds; Peter M Colman; Suzanne Cory
Subversion of the Bcl-2 life/death switch in cancer development and therapy.
Cold Spring Harbor symposia on quantitative biology 2005;70():469-77.