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Garnett Kelsoe

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Guang Yang; S Munir Alam; Derek W Cain; Barton F Haynes; T Matt Holl; Thomas B Kepler; Yi Li; Hua-Xin Liao; Yang Liu; Xiaozhi Lu; Nathan I Nicely; Leonard Spicer; John L VandeBerg; Garnett Kelsoe
Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies.
Derek W Cain; Michael M Cunningham; Sergio E Sanders; Garnett Kelsoe
Disparate adjuvant properties among three formulations of "alum".
M Anthony Moody; Robert Parks; Joy Pickeral; Justin Pollara; Julia Cavanaugh Scull; Georgia D Tomaras; Nathan A Vandergrift; Gerald Voss; Lu Wang; John F Whitesides; Nicole L Yates; Jae-Sung Yu; Ruijun Zhang; S Munir Alam; Joshua D Amos; Xi Chen; Mark S Drinker; Joshua A Eudailey; Guido Ferrari; Andrew Foulger; Thaddeus C Gurley; Garnett Kelsoe; Hua-Xin Liao; Dawn J Marshall; R Ryan Meyerhoff; David C Montefiori; Barton F Haynes
HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages.

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All Publications

2013: Guang Yang; S Munir Alam; Derek W Cain; Barton F Haynes; T Matt Holl; Thomas B Kepler; Yi Li; Hua-Xin Liao; Yang Liu; Xiaozhi Lu; Nathan I Nicely; Leonard Spicer; John L VandeBerg; Garnett Kelsoe
Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies.
The Journal of experimental medicine 2013;210(2):241-56.
2013: Derek W Cain; Michael M Cunningham; Sergio E Sanders; Garnett Kelsoe
Disparate adjuvant properties among three formulations of "alum".
Vaccine 2013;31(4):653-60.
2012: M Anthony Moody; Robert Parks; Joy Pickeral; Justin Pollara; Julia Cavanaugh Scull; Georgia D Tomaras; Nathan A Vandergrift; Gerald Voss; Lu Wang; John F Whitesides; Nicole L Yates; Jae-Sung Yu; Ruijun Zhang; S Munir Alam; Joshua D Amos; Xi Chen; Mark S Drinker; Joshua A Eudailey; Guido Ferrari; Andrew Foulger; Thaddeus C Gurley; Garnett Kelsoe; Hua-Xin Liao; Dawn J Marshall; R Ryan Meyerhoff; David C Montefiori; Barton F Haynes
HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages.
Journal of virology 2012;86(14):7496-507.
2012: Barton F Haynes; Garnett Kelsoe; Stephen C Harrison; Thomas B Kepler
B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study.
Nature biotechnology 2012;30(5):423-33.
2012: James Friedman; Barton F Haynes; Garnett Kelsoe; Hua-Xin Liao; M Anthony Moody; S Munir Alam; Kara Anasti; Guido Ferrari; Genevieve G Fouda; Justin Pollara; Xiaoying Shen; Shelley Stewart; Georgia D Tomaras; Shi-Mao Xia; Guang Yang; Sallie R Permar
Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum.
PloS one 2012;7(5):e37648.
2011: S Munir Alam; Kara Anasti; Bing Chen; S Moses Dennison; Michele Donathan; Andrew Foulger; Frederick Jaeger; Garnett Kelsoe; Thomas B Kepler; Hua-Xin Liao; Judith Lucas; Nathan Nicely; Robert Parks; Georgia D Tomaras; Laurent Verkoczy; Barton F Haynes
Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation.
Journal of virology 2011;85(22):11725-31.
2011: Masayuki Kuraoka; Garnett Kelsoe
A novel role for activation-induced cytidine deaminase: central B-cell tolerance.
Cell cycle (Georgetown, Tex.) 2011;10(20):3423-4.
2011: Laurent Verkoczy; Jinsong Zhang; S Munir Alam; Hilary Bouton-Verville; Yao Chen; Marilyn Diaz; T Matt Holl; Jennifer Hutchinson; Kwan-Ki Hwang; Garnett Kelsoe; Ying-Bin Ouyang; Barton F Haynes
Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(7):3785-97.
2011: Masayuki Kuraoka; Dongmei Liao; Alexander E Reynolds; Mandy Womble; Derek W Cain; T Matt Holl; Garnett Kelsoe
Activation-induced cytidine deaminase mediates central tolerance in B cells.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(28):11560-5.
2011: Laurent Verkoczy; Garnett Kelsoe; M Anthony Moody; Barton F Haynes
Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodies.
Current opinion in immunology 2011;23(3):383-90.
2011: Eda K Holl; Brian P O'Connor; T Matt Holl; Kelly E Roney; Albert G Zimmermann; Sushmita Jha; Garnett Kelsoe; Jenny P-Y Ting
Plexin-D1 is a novel regulator of germinal centers and humoral immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(10):5603-11.
2011: Garnett Kelsoe
B cell tolerance: putting the horse before the cart.
Arthritis and rheumatism 2011;63(5):1173-6.
2011: Patrick O McGowan; Thomas A Hope; Warren H Meck; Garnett Kelsoe; Christina L Williams
Impaired social recognition memory in recombination activating gene 1-deficient mice.
Brain research 2011;1383():187-95.
2011: Masayuki Kuraoka; Laurie McWilliams; Garnett Kelsoe
AID expression during B-cell development: searching for answers.
Immunologic research 2011;49(1-3):3-13.
2011: Derek W Cain; Gregory D Sempowski; Pilar B Snowden; Garnett Kelsoe
Inflammation triggers emergency granulopoiesis through a density-dependent feedback mechanism.
PloS one 2011;6(5):e19957.
2010: Garnett Kelsoe; Derek Cain
A new guise for hyper-IgM syndrome.
Blood 2010;116(26):5785-6.
2010: Nathan I Nicely; S Moses Dennison; Leonard Spicer; Richard M Scearce; Garnett Kelsoe; Yoshihiro Ueda; Haiyan Chen; Hua-Xin Liao; S Munir Alam; Barton F Haynes
Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region.
Nature structural & molecular biology 2010;17(12):1492-4.
2010: Huaiyong Chen; Dongmei Liao; T Matt Holl; Pilar Snowden; Yoshihiro Ueda; Garnett Kelsoe
Genetic regulation of pristane-induced oil granuloma responses.
International journal of experimental pathology 2010;91(5):472-83.
2010: Huaiyong Chen; Dongmei Liao; Derek Cain; Ian McLeod; Yoshihiro Ueda; Ziqiang Guan; Christian Raetz; Garnett Kelsoe
Distinct granuloma responses in C57BL/6J and BALB/cByJ mice in response to pristane.
International journal of experimental pathology 2010;91(5):460-71.
2010: T Matt Holl; Barton F Haynes; Garnett Kelsoe
Stromal cell independent B cell development in vitro: generation and recovery of autoreactive clones.
Journal of immunological methods 2010;354(1-2):53-67.
2010: Laurent Verkoczy; Marilyn Diaz; T Matt Holl; Ying-Bin Ouyang; Hilary Bouton-Verville; S Munir Alam; Hua-Xin Liao; Garnett Kelsoe; Barton F Haynes
Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(1):181-6.
2009: Masayuki Kuraoka; Dongmei Liao; Kaiyong Yang; Sallie D Allgood; Marc C Levesque; Garnett Kelsoe; Yoshihiro Ueda
Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(5):3237-48.
2009: Mattia Bonsignori; M Anthony Moody; Robert J Parks; T Matt Holl; Garnett Kelsoe; Charles B Hicks; Nathan Vandergrift; Georgia D Tomaras; Barton F Haynes
HIV-1 envelope induces memory B cell responses that correlate with plasma antibody levels after envelope gp120 protein vaccination or HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(4):2708-17.
2009: Marc C Levesque; M Anthony Moody; Kwan-Ki Hwang; Dawn J Marshall; John F Whitesides; Joshua D Amos; Thaddeus C Gurley; Sallie Allgood; Benjamin B Haynes; Nathan A Vandergrift; Steven Plonk; Daniel C Parker; Myron S Cohen; Georgia D Tomaras; Paul A Goepfert; George M Shaw; Joern schmitz; Joseph J Eron; Nicholas J Shaheen; Charles B Hicks; Hua-Xin Liao; Martin Markowitz; Garnett Kelsoe; David M Margolis; Barton F Haynes
Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection.
PLoS medicine 2009;6(7):e1000107.
2009: Yoshihiro Ueda; Derek W Cain; Masayuki Kuraoka; Motonari Kondo; Garnett Kelsoe
IL-1R type I-dependent hemopoietic stem cell proliferation is necessary for inflammatory granulopoiesis and reactive neutrophilia.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6477-84.
2009: Derek Cain; Motonari Kondo; Huaiyong Chen; Garnett Kelsoe
Effects of acute and chronic inflammation on B-cell development and differentiation.
The Journal of investigative dermatology 2009;129(2):266-77.
2009: Laurent Verkoczy; M Anthony Moody; T Matt Holl; Hilary Bouton-Verville; Richard M Scearce; Jennifer Hutchinson; S Munir Alam; Garnett Kelsoe; Barton F Haynes
Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region.
PloS one 2009;4(10):e7215.
2009: Anne E Lieberman; Masayuki Kuraoka; Marco Davila; Garnett Kelsoe; Lindsay G Cowell
Conserved cryptic recombination signals in Vkappa gene segments are cleaved in small pre-B cells.
BMC immunology 2009;10():37.
2008: David J DiLillo; Yasuhito Hamaguchi; Yoshihiro Ueda; Kaiyong Yang; Junji Uchida; Karen M Haas; Garnett Kelsoe; Thomas F Tedder
Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):361-71.
2007: Marco Davila; Feifei Liu; Lindsay G Cowell; Anne E Lieberman; Emily Heikamp; Anjali Patel; Garnett Kelsoe
Multiple, conserved cryptic recombination signals in VH gene segments: detection of cleavage products only in pro B cells.
The Journal of experimental medicine 2007;204(13):3195-208.
2007: S Munir Alam; Mildred McAdams; David Boren; Michael Rak; Richard M Scearce; Feng Gao; Zenaido T Camacho; Daniel Gewirth; Garnett Kelsoe; Pojen Chen; Barton F Haynes
The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4424-35.
2007: Yoshihiro Ueda; Dongmei Liao; Kaiyong Yang; Anjali Patel; Garnett Kelsoe
T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3593-601.
2007: Alicia D Volkheimer; J Brice Weinberg; Bethany E Beasley; John F Whitesides; Jon P Gockerman; Joseph O Moore; Garnett Kelsoe; Barbara K Goodman; Marc C Levesque
Progressive immunoglobulin gene mutations in chronic lymphocytic leukemia: evidence for antigen-driven intraclonal diversification.
Blood 2007;109(4):1559-67.
2006: Janet M Murray; J Patrick O'Neill; Terri Messier; Jami Rivers; Vernon E Walker; Brien McGonagle; Lucy M Trombley; Lindsay G Cowell; Garnett Kelsoe; Fraser McBlane; Barry A Finette
V(D)J recombinase-mediated processing of coding junctions at cryptic recombination signal sequences in peripheral T cells during human development.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(8):5393-404.
2006: T Matt Holl; Garnett Kelsoe
Outside influence: TLRs direct hematopoietic cell fates.
Immunity 2006;24(6):667-9.
2005: Yoshihiro Ueda; Motonari Kondo; Garnett Kelsoe
Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow.
The Journal of experimental medicine 2005;201(11):1771-80.
2005: Barton F Haynes; M Anthony Moody; Laurent Verkoczy; Garnett Kelsoe; S Munir Alam
Antibody polyspecificity and neutralization of HIV-1: a hypothesis.
Human antibodies 2005;14(3-4):59-67.
2004: Lindsay G Cowell; Marco Davila; Dale A Ramsden; Garnett Kelsoe
Computational tools for understanding sequence variability in recombination signals.
Immunological reviews 2004;200():57-69.
2004: Michael D Gunn; Garnett Kelsoe
Should we B-leavin' now?
Nature immunology 2004;5(7):703-4.
2004: Yoshihiro Ueda; Kaiyong Yang; Sandra J Foster; Motonari Kondo; Garnett Kelsoe
Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression.
The Journal of experimental medicine 2004;199(1):47-58.
2003: Alexei A Sharov; Yulan Piao; Ryo Matoba; Dawood B Dudekula; Yong Qian; Vincent VanBuren; Geppino Falco; Patrick R Martin; Carole A Stagg; Uwem C Bassey; Yuxia Wang; Mark Carter; Toshio Hamatani; Kazuhiro Aiba; Hidenori Akutsu; Lioudmila Sharova; Tetsuya S Tanaka; Wendy L Kimber; Toshiyuki Yoshikawa; Saied A Jaradat; Serafino Pantano; Ramaiah Nagaraja; Kenneth R Boheler; Dennis Taub; Richard J Hodes; Dan Longo; David Schlessinger; Jonathan Keller; Emily Klotz; Garnett Kelsoe; Akihiro Umezawa; Angelo L Vescovi; Janet Rossant; Tilo Kunath; Brigid L M Hogan; Anna Curci; Michele D'Urso; Janet Kelso; Winston Hide; Minoru S H Ko
Transcriptome analysis of mouse stem cells and early embryos.
PLoS biology 2003;1(3):E74.
2003: Paul W Kincade; Garnett Kelsoe
A birthday for B cells: Lymphopoiesis II, a scientific symposium honoring Max Cooper.
Nature immunology 2003;4(12):1155-7.
2003: Garnett Kelsoe
Therapeutic CD154 antibody for lupus: promise for the future?
The Journal of clinical investigation 2003;112(10):1480-2.
2003: Alfred Ian Lee; Sebastian D Fugmann; Lindsay G Cowell; Leon M Ptaszek; Garnett Kelsoe; David G Schatz
A functional analysis of the spacer of V(D)J recombination signal sequences.
PLoS biology 2003;1(1):E1.
2003: Shuhua Han; Kaiyong Yang; Zeynep Ozen; Weiyi Peng; Ekaterina Marinova; Garnett Kelsoe; B Zheng
Enhanced differentiation of splenic plasma cells but diminished long-lived high-affinity bone marrow plasma cells in aged mice.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(3):1267-73.
2003: Lindsay G Cowell; Marco Davila; Kaiyong Yang; Thomas B Kepler; Garnett Kelsoe
Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling.
The Journal of experimental medicine 2003;197(2):207-20.
2002: Hong-Erh Liang; Lih-Yun Hsu; Dragana Cado; Lindsay G Cowell; Garnett Kelsoe; Mark S Schlissel
The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development.
Immunity 2002;17(5):639-51.
2002: Joseph M Dal Porto; Ann M Haberman; Garnett Kelsoe; Mark J Shlomchik
Very low affinity B cells form germinal centers, become memory B cells, and participate in secondary immune responses when higher affinity competition is reduced.
The Journal of experimental medicine 2002;195(9):1215-21.
2002: Lindsay G Cowell; Marco Davila; Thomas B Kepler; Garnett Kelsoe
Identification and utilization of arbitrary correlations in models of recombination signal sequences.
Genome biology 2002;3(12):RESEARCH0072.
2001: Irina G Luzina; Sergei Atamas; CE Storrer; L C daSilva; Garnett Kelsoe; John C Papadimitriou; Barry Handwerger
Spontaneous formation of germinal centers in autoimmune mice.
Journal of leukocyte biology 2001;70(4):578-84.
2001: Peter C Sandel; M Gendelman; Garnett Kelsoe; John G Monroe
Definition of a novel cellular constituent of the bone marrow that regulates the response of immature B cells to B cell antigen receptor engagement.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):5935-44.
2001: Marco Davila; S Foster; Garnett Kelsoe; Kaiyong Yang
A role for secondary V(D)J recombination in oncogenic chromosomal translocations?
Advances in cancer research 2001;81():61-92.
2001: Douglas M Cerasoli; Garnett Kelsoe; Marcella Sarzotti
CD4+Thy1- thymocytes with a Th-type 2 cytokine response.
International immunology 2001;13(1):75-83.
2000: Zhibin Chen; SB Koralov; Garnett Kelsoe
Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2.
The Journal of experimental medicine 2000;192(9):1339-52.
2000: Garnett Kelsoe
Remembrance of things past.
Nature immunology 2000;1(5):375-6.
2000: Zhibin Chen; SB Koralov; Garnett Kelsoe
Regulation of humoral immune responses by CD21/CD35.
Immunological reviews 2000;176():194-204.
2000: Zhibin Chen; SB Koralov; M Gendelman; M C Carroll; Garnett Kelsoe
Humoral immune responses in Cr2-/- mice: enhanced affinity maturation but impaired antibody persistence.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4522-32.
2000: S D Langdon; M Inaioki; Garnett Kelsoe; Thomas F Tedder
Germline sequences of V(H)7183 gene family members in C57BL/6 mice demonstrate natural selection of particular sequences during recent evolution.
Immunogenetics 2000;51(3):241-5.
2000: Garnett Kelsoe
Studies of the humoral immune response.
Immunologic research 2000;22(2-3):199-210.
1999: Y Takahashi; Douglas M Cerasoli; Joseph M Dal Porto; Michiko Shimoda; R Freund; W Fang; David G Telander; EN Malvey; Daniel L Mueller; timothy wayne behrens; Garnett Kelsoe
Relaxed negative selection in germinal centers and impaired affinity maturation in bcl-xL transgenic mice.
The Journal of experimental medicine 1999;190(3):399-410.
1999: Robert J Monroe; KJ Seidl; F Gaertner; S Han; F Chen; JoAnn Sekiguchi; J Wang; R Ferrini; L Davidson; Garnett Kelsoe; Frederick W Alt
RAG2:GFP knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues.
Immunity 1999;11(2):201-12.
1999: Garnett Kelsoe
V(D)J hypermutation and receptor revision: coloring outside the lines.
Current opinion in immunology 1999;11(1):70-5.
1999: Kaiyong Yang; Marco Davila; Garnett Kelsoe
Do germinal centers have a role in the generation of lymphomas?
Current topics in microbiology and immunology 1999;246():53-60; discussion 61-2.
1998: Joseph M Dal Porto; Ann M Haberman; Mark J Shlomchik; Garnett Kelsoe
Antigen drives very low affinity B cells to become plasmacytes and enter germinal centers.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(10):5373-81.
1998: M D Radmacher; Garnett Kelsoe; Thomas B Kepler
Predicted and inferred waiting times for key mutations in the germinal centre reaction: evidence for stochasticity in selection.
Immunology and cell biology 1998;76(4):373-81.
1998: Garnett Kelsoe
V(D)J hypermutation and DNA mismatch repair: vexed by fixation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6576-7.
1998: MB Fischer; S Goerg; Ling Shen; AP Prodeus; C C Goodnow; Garnett Kelsoe; Michael C Carroll
Dependence of germinal center B cells on expression of CD21/CD35 for survival.
Science (New York, N.Y.) 1998;280(5363):582-5.
1998: B Zheng; S Han; E Spanopoulou; Garnett Kelsoe
Immunoglobulin gene hypermutation in germinal centers is independent of the RAG-1 V(D)J recombinase.
Immunological reviews 1998;162():133-41.
1998: Y Takahashi; Pinaki R Dutta; Douglas M Cerasoli; Garnett Kelsoe
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affinity maturation develops in two stages of clonal selection.
The Journal of experimental medicine 1998;187(6):885-95.
1998: J Przylepa; Carrie D Dorsey; Garnett Kelsoe
Lymphocyte development and selection in germinal centers.
Current topics in microbiology and immunology 1998;229():85-104.
1997: B Zheng; S Han; Y Takahashi; Garnett Kelsoe
Immunosenescence and germinal center reaction.
Immunological reviews 1997;160():63-77.
1997: S Han; S R Dillon; B Zheng; Michiko Shimoda; Mark S Schlissel; Garnett Kelsoe
V(D)J recombinase activity in a subset of germinal center B lymphocytes.
Science (New York, N.Y.) 1997;278(5336):301-5.
1997: S Han; B Zheng; Y Takahashi; Garnett Kelsoe
Distinctive characteristics of germinal center B cells.
Seminars in immunology 1997;9(4):255-60.
1996: S Han; B Zheng; David G Schatz; E Spanopoulou; Garnett Kelsoe
Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells.
Science (New York, N.Y.) 1996;274(5295):2094-7.
1996: B Zheng; S Han; Q Zhu; R Goldsby; Garnett Kelsoe
Alternative pathways for the selection of antigen-specific peripheral T cells.
Nature 1996;384(6606):263-6.
1996: W Pao; Li Wen; AL Smith; A Gulbranson-Judge; B Zheng; Garnett Kelsoe; I C MacLennan; MJ Owen; Adrian C Hayday
Gamma delta T cell help of B cells is induced by repeated parasitic infection, in the absence of other T cells.
Current biology : CB 1996;6(10):1317-25.
1996: B Zheng; S Han; Garnett Kelsoe
T helper cells in murine germinal centers are antigen-specific emigrants that downregulate Thy-1.
The Journal of experimental medicine 1996;184(3):1083-91.
1996: MB Fischer; Minghe Ma; S Goerg; X Zhou; J Xia; O Finco; S Han; Garnett Kelsoe; R G Howard; Thomas L Rothstein; Elisabeth Kremmer; Fred S Rosen; Michael C Carroll
Regulation of the B cell response to T-dependent antigens by classical pathway complement.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(2):549-56.
1996: S E Ferguson; S Han; Garnett Kelsoe; Craig Thompson
CD28 is required for germinal center formation.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(12):4576-81.
1996: Garnett Kelsoe
The germinal center: a crucible for lymphocyte selection.
Seminars in immunology 1996;8(3):179-84.
1996: Li Wen; W Pao; F Susan Wong; Q Peng; Joe Craft; B Zheng; Garnett Kelsoe; L Dianda; MJ Owen; Adrian C Hayday
Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells.
The Journal of experimental medicine 1996;183(5):2271-82.
1996: D A Croix; Joseph M Ahearn; ARIELLA ROSENGARD; S Han; Garnett Kelsoe; Minghe Ma; Michael C Carroll
Antibody response to a T-dependent antigen requires B cell expression of complement receptors.
The Journal of experimental medicine 1996;183(4):1857-64.
1996: Garnett Kelsoe
Life and death in germinal centers (redux).
Immunity 1996;4(2):107-11.
1996: B Zheng; Garnett Kelsoe; S Han
Somatic diversification of antibody responses.
Journal of clinical immunology 1996;16(1):1-11.
1995: S Han; B Zheng; Joseph M Dal Porto; Garnett Kelsoe
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance.
The Journal of experimental medicine 1995;182(6):1635-44.
1995: C Miller; Garnett Kelsoe
Ig VH hypermutation is absent in the germinal centers of aged mice.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(7):3377-84.
1995: S Han; Karen S Hathcock; B Zheng; Thomas B Kepler; Richard J Hodes; Garnett Kelsoe
Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(2):556-67.
1995: Garnett Kelsoe
The germinal center reaction.
Immunology today 1995;16(7):324-6.
1995: C Miller; J Stedra; Garnett Kelsoe; Jan Cerny
Facultative role of germinal centers and T cells in the somatic diversification of IgVH genes.
The Journal of experimental medicine 1995;181(4):1319-31.
1995: Azad Kaushik; Garnett Kelsoe; Jean-Claude Jaton
The nude mutation results in impaired primary antibody repertoire.
European journal of immunology 1995;25(2):631-4.
1995: Y Saitoh; Garnett Kelsoe; Constantin A Bona; Azad Kaushik
Skewed VH and V kappa gene family expression and pairing occurs among B lymphocytes in autoimmune motheaten mice.
Autoimmunity 1995;21(3):185-193.
1995: Garnett Kelsoe
In situ studies of the germinal center reaction.
Advances in immunology 1995;60():267-88.
1994: B Zheng; W Xue; Garnett Kelsoe
Locus-specific somatic hypermutation in germinal centre T cells.
Nature 1994;372(6506):556-9.
1994: Garnett Kelsoe
B cell diversification and differentiation in the periphery.
The Journal of experimental medicine 1994;180(1):5-6.
1993: Joshy Jacob; J Przylepa; C Miller; Garnett Kelsoe
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells.
The Journal of experimental medicine 1993;178(4):1293-307.
1993: Vladimir V Yurovsky; Garnett Kelsoe
Pairing of VH gene families with the lambda 1 light chain: evidence for a non-stochastic association.
European journal of immunology 1993;23(8):1975-9.
1993: Garnett Kelsoe; B Zheng
Sites of B-cell activation in vivo.
Current opinion in immunology 1993;5(3):418-22.
1992: Joshy Jacob; Garnett Kelsoe
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers.
The Journal of experimental medicine 1992;176(3):679-87.
1992: E A Goidl; Jan Cerny; Garnett Kelsoe; Dan H Schulze
Aging and humoral immunity.
Maryland medical journal (Baltimore, Md. : 1985) 1992;41(7):609-13.
1992: Joshy Jacob; C Miller; Garnett Kelsoe
In situ studies of the antigen-driven somatic hypermutation of immunoglobulin genes.
Immunology and cell biology 1992;70 ( Pt 2)():145-52.
1991: Joshy Jacob; Garnett Kelsoe; K Rajewsky; U Weiss
Intraclonal generation of antibody mutants in germinal centres.
Nature 1991;354(6352):389-92.
1991: Joshy Jacob; R Kassir; Garnett Kelsoe
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations.
The Journal of experimental medicine 1991;173(5):1165-75.
1991: Azad Kaushik; Luc Reininger; Garnett Kelsoe; Jean-Claude Jaton; Constantin A Bona
Contribution of the VH11 gene family to mitogen-responsive B cell repertoire in C57BL/6 mice.
European journal of immunology 1991;21(3):827-30.
1991: M Sarzotti; V Kumar; M Bennett; Garnett Kelsoe
Cloning of murine splenic T lymphocytes and natural killer (NK) cells on filter paper discs: detection of a novel NK/T phenotype.
European journal of immunology 1991;21(3):635-41.
1991: Garnett Kelsoe
The primary antibody repertoire: the somatic genotype and paratopic phenotype of B-cell populations.
Immunology series 1991;55():81-92.
1990: Constantin A Bona; Y Saitoh; Garnett Kelsoe
Pairing of VK and VK gene families in self-reactive antibodies.
Journal of clinical immunology 1990;10(5):223-36.
1990: Azad Kaushik; Dan H Schulze; F A Bonilla; Constantin A Bona; Garnett Kelsoe
Stochastic pairing of heavy-chain and kappa light-chain variable gene families occurs in polyclonally activated B cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(13):4932-6.
1990: C C Striebich; R M Miceli; Dan H Schulze; Garnett Kelsoe; Jan Cerny
Antigen-binding repertoire and Ig H chain gene usage among B cell hybridomas from normal and autoimmune mice.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(5):1857-65.
1989: Azad Kaushik; Dan H Schulze; Constantin A Bona; Garnett Kelsoe
Murine V kappa gene expression does not follow the VH paradigm.
The Journal of experimental medicine 1989;169(5):1859-64.
1989: Garnett Kelsoe; R Miceli; Jan Cerny; Dan H Schulze
Mapping of antibody specificities to VH gene families.
Immunogenetics 1989;29(5):288-96.
1987: Dan H Schulze; Garnett Kelsoe
Genotypic analysis of B cell colonies by in situ hybridization. Stoichiometric expression of three VH families in adult C57BL/6 and BALB/c mice.
The Journal of experimental medicine 1987;166(1):163-72.
1987: Garnett Kelsoe
Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper disks: phenotypic and genotypic analysis of B cell colonies.
Methods in enzymology 1987;150():287-304.
1986: Garnett Kelsoe; J T Stout
Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper discs. II. Paratope frequencies within the mitogen-selected repertoire.
Cellular immunology 1986;98(2):506-16.
1986: Garnett Kelsoe
Regulation of the immune response. II. Concomitant idiotope-specific enhancement and suppression can result in a phenotypically normal response.
Cellular immunology 1986;98(1):145-55.
1985: Garnett Kelsoe
Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper discs. I. A description of the technique and of methods for the analysis of colonies.
Journal of immunological methods 1985;76(2):345-63.
1984: Garnett Kelsoe
Network interactions, 1983.
Survey of immunologic research 1984;3(2-3):169-71.
1983: D L Sacks; Garnett Kelsoe; D H Sachs
Induction of immune responses with anti-idiotypic antibodies: implications for the induction of protective immunity.
Springer seminars in immunopathology 1983;6(1):79-97.
1983: Garnett Kelsoe
Network interactions, 1982: audivi, legi, fugi.
Survey of immunologic research 1983;2(3):230-2.
1983: Konrad Beyreuther; J Bovens; M Brüggemann; R Dildrop; Garnett Kelsoe; U Krawinkel; C Müller; S Nishikawa; Andreas Radbruch; M Reth
Idiotypic determinants used in the analysis of antibody diversification and as regulatory targets.
Annals of the New York Academy of Sciences 1983;418():121-9.
1981: Garnett Kelsoe; M Reth; K Rajewsky
Control of idiotope expression by monoclonal anti-idiotope and idiotope-bearing antibody.
European journal of immunology 1981;11(5):418-23.
1981: M Reth; Garnett Kelsoe; K Rajewsky
Idiotypic regulation by isologous monoclonal anti-idiotope antibodies.
Nature 1981;290(5803):257-9.
1980: Garnett Kelsoe; D Isaak; Jan Cerny
Thymic requirement for cyclical idiotypic and reciprocal anti-idiotypic immune responses to a T-independent antigen.
The Journal of experimental medicine 1980;151(2):289-300.
1980: Garnett Kelsoe; M Reth; K Rajewsky
Control idiotope expression by monoclonal anti-idiotope antibodies.
Immunological reviews 1980;52():75-88.
1979: Garnett Kelsoe; Jan Cerny
Reciprocal expansions of idiotypic and anti-idiotypic clones following antigen stimulation.
Nature 1979;279(5711):333-4.
1979: J A Shadduck; Garnett Kelsoe; R J Helmke
A microsporidan contaminant of a nonhuman primate cell culture: ultrastructural comparison with Nosema connori.
The Journal of parasitology 1979;65(1):185-8.
1978: Garnett Kelsoe; T H Weller
Immunodiagnosis of infection with Schistosoma mansoni: enzyme-linked immunosorbent assay for detection of antibody to circulating antigen.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(11):5715-7.
1978: Garnett Kelsoe; Jan Cerny
Regulation of the immune response. I. Regulatory cell equilibrium in the "virgin" state.
European journal of immunology 1978;8(3):176-80.
1977: Garnett Kelsoe; J E Ubelaker; V F Allison
The fine structure of spermatogenesis in Hymenolepis diminuta (Cestoda) with a description of the mature spermatozoon.
Zeitschrift für Parasitenkunde (Berlin, Germany) 1977;54(2):175-87.