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Merike Kelve

Research Profile

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TOP 3
Annika Lopp; Tõnu Reintamm; Salvatore de Rosa; Anne Kuusksalu; Merike Kelve
A novel endoribonuclease from the marine sponge Tethya aurantium specific to 2',5'-phosphodiester bonds.
Kerli Vallmann; Nele Aas; Tõnu Reintamm; Annika Lopp; Anne Kuusksalu; Merike Kelve
Expressed 2-5A synthetase genes and pseudogenes in the marine sponge Geodia barretti.
B Luthringer; S Isbert; W E G Müller; C Zilberberg; Narsinh L Thakur; G Wörheide; R H Stauber; Merike Kelve; Matthias Wiens
Poriferan survivin exhibits a conserved regulatory role in the interconnected pathways of cell cycle and apoptosis.

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All Publications

2012: Annika Lopp; Tõnu Reintamm; Salvatore de Rosa; Anne Kuusksalu; Merike Kelve
A novel endoribonuclease from the marine sponge Tethya aurantium specific to 2',5'-phosphodiester bonds.
Biochimie 2012;94(8):1635-46.
2011: Kerli Vallmann; Nele Aas; Tõnu Reintamm; Annika Lopp; Anne Kuusksalu; Merike Kelve
Expressed 2-5A synthetase genes and pseudogenes in the marine sponge Geodia barretti.
Gene 2011;478(1-2):42-9.
2011: B Luthringer; S Isbert; W E G Müller; C Zilberberg; Narsinh L Thakur; G Wörheide; R H Stauber; Merike Kelve; Matthias Wiens
Poriferan survivin exhibits a conserved regulatory role in the interconnected pathways of cell cycle and apoptosis.
Cell death and differentiation 2011;18(2):201-13.
2010: Annika Lopp; Tõnu Reintamm; Anne Kuusksalu; Indrek Tammiste; Arno Pihlak; Merike Kelve
Natural occurrence of 2',5'-linked heteronucleotides in marine sponges.
Marine drugs 2010;8(2):235-54.
2009: Karina Hansen Kjaer; Jesper Buchhave Poulsen; Tõnu Reintamm; Emilie Saby; Pia M Martensen; Merike Kelve; Just Justesen
Evolution of the 2'-5'-oligoadenylate synthetase family in eukaryotes and bacteria.
Journal of molecular evolution 2009;69(6):612-24.
2009: Emilie Saby; Jesper Buchhave Poulsen; Just Justesen; Merike Kelve; Maria Jesus Uriz
2'-phosphodiesterase and 2',5'-oligoadenylate synthetase activities in the lowest metazoans, sponge [porifera].
Biochimie 2009;91(11-12):1531-4.
2009: Emilie Saby; Just Justesen; Merike Kelve; Maria J Uriz
In vitro effects of metal pollution on Mediterranean sponges: species-specific inhibition of 2',5'-oligoadenylate synthetase.
Aquatic toxicology (Amsterdam, Netherlands) 2009;94(3):204-10.
2008: Tõnu Reintamm; Anne Kuusksalu; Madis Metsis; Mailis Päri; Kerli Vallmann; Annika Lopp; Just Justesen; Merike Kelve
Sponge OAS has a distinct genomic structure within the 2-5A synthetase family.
Molecular genetics and genomics : MGG 2008;280(5):453-66.
2007: Mailis Päri; Anne Kuusksalu; Annika Lopp; Tõnu Reintamm; Just Justesen; Merike Kelve
Expression and characterization of recombinant 2',5'-oligoadenylate synthetase from the marine sponge Geodia cydonium.
The FEBS journal 2007;274(13):3462-74.
2003: Tõnu Reintamm; Annika Lopp; Anne Kuusksalu; Tonis Pehk; Merike Kelve
ATP N-glycosidase - a novel ATP-converting activity from a marine sponge Axinella polypoides.
European journal of biochemistry / FEBS 2003;270(20):4122-32.
2003: Tõnu Reintamm; Annika Lopp; Anne Kuusksalu; Juhan Subbi; Merike Kelve
Qualitative and quantitative aspects of 2-5A synthesizing capacity of different marine sponges.
Biomolecular engineering 2003;20(4-6):389-99.
2003: Merike Kelve; Anne Kuusksalu; Annika Lopp; Tõnu Reintamm
Sponge (2',5')oligoadenylate synthetase activity in the whole sponge organism and in a primary cell culture.
Journal of biotechnology 2003;100(2):177-80.
2002: Annika Lopp; Anne Kuusksalu; Tõnu Reintamm; Werner E G Müller; Merike Kelve
2',5'-oligoadenylate synthetase from a lower invertebrate, the marine sponge Geodia cydonium, does not need dsRNA for its enzymatic activity.
Biochimica et biophysica acta 2002;1590(1-3):140-9.
2002: Vladislav A Grebenjuk; Anne Kuusksalu; Merike Kelve; Joachim Schütze; Heinz C Schröder; Werner E G Müller
Induction of (2'-5')oligoadenylate synthetase in the marine sponges Suberites domuncula and Geodia cydonium by the bacterial endotoxin lipopolysaccharide.
European journal of biochemistry / FEBS 2002;269(5):1382-92.
2001: Katrin Sak; K Samuel; Merike Kelve; Tania E Webb
Pharmacological characterisation of pyrimidinoceptor responses in NG108-15 cells.
European journal of pharmacology 2001;415(2-3):127-33.
2000: Katrin Sak; Asko Uri; Erki Enkvist; Gerda Raidaru; Juhan Subbi; Merike Kelve; Jaak Järv
Adenosine-derived non-phosphate antagonists for P2Y(1) purinoceptors.
Biochemical and biophysical research communications 2000;272(2):327-31.
2000: Annika Lopp; Anne Kuusksalu; K Samuel; Merike Kelve
Expression and activity of 2-5A synthetase in the course of differentiation and apoptosis of PC12 cells.
Cytokine 2000;12(6):737-41.
1999: Matthias Wiens; Anne Kuusksalu; Merike Kelve; Werner E G Müller
Origin of the interferon-inducible (2'-5')oligoadenylate synthetases: cloning of the (2'-5')oligoadenylate synthetase from the marine sponge Geodia cydonium.
FEBS letters 1999;462(1-2):12-8.
1999: Katrin Sak; Tania E Webb; K Samuel; Merike Kelve; Jaak Järv
Only pyrimidinoceptors are functionally expressed in mouse neuroblastoma cell lines.
Molecular cell biology research communications : MCBRC 1999;1(3):203-8.
1998: Katrin Sak; Merike Kelve; Asko Uri; Jaak Järv
Pyrimidinoceptor potentiation by ATP in NG108-15 cells.
FEBS letters 1998;439(1-2):107-9.
1998: Anne Kuusksalu; Juhan Subbi; Tonis Pehk; Tõnu Reintamm; Werner E G Müller; Merike Kelve
Identification of the reaction products of (2'-5')oligoadenylate synthetase in the marine sponge.
European journal of biochemistry / FEBS 1998;257(2):420-6.
1996: W E Müller; G Pergande; Hiroshi Ushijima; C Schleger; Merike Kelve; S Perovic
Neurotoxicity in rat cortical cells caused by N-methyl-D-aspartate (NMDA) and gp120 of HIV-1: induction and pharmacological intervention.
Progress in molecular and subcellular biology 1996;16():44-57.
1995: S Perovic; G Pergande; Hiroshi Ushijima; Merike Kelve; J Forrest; W E Müller
Flupirtine partially prevents neuronal injury induced by prion protein fragment and lead acetate.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1995;4(4):369-74.
1995: Anne Kuusksalu; A Pihlak; W E Müller; Merike Kelve
The (2'-5')oligoadenylate synthetase is present in the lowest multicellular organisms, the marine sponges. Demonstration of the existence and identification of its reaction products.
European journal of biochemistry / FEBS 1995;232(2):351-7.
1995: Anne Kuusksalu; E Truve; A Aaspollu; Merike Kelve; U Scheffer; W E Müller; Heinz C Schröder
Impairment of intracellular antiviral defense with age: age-dependent changes in expression of interferon-induced and double-stranded RNA-activated 2-5A synthetase in rat.
Mechanisms of ageing and development 1995;78(2):103-15.
1994: Merike Kelve; E Truve; A Aaspollu; Anne Kuusksalu; J Dapper; S Perovic; W E Müller; Heinz C Schröder
Rapid reduction of mRNA coding for 2'-5'-oligoadenylate synthetase in rat pheochromocytoma PC12 cells during apoptosis.
Cellular and molecular biology (Noisy-le-Grand, France) 1994;40(2):165-73.
1994: E Truve; Merike Kelve; A Aaspollu; Heinz C Schröder; W E Müller
Homologies between different forms of 2-5A synthetases.
Progress in molecular and subcellular biology 1994;14():139-49.
1994: E Truve; Merike Kelve; A Aaspôllu; Anne Kuusksalu; P Seppänen; Mart Saarma
Principles and background for the construction of transgenic plants displaying multiple virus resistance.
Archives of virology. Supplementum 1994;9():41-50.
1993: E Truve; A Aaspôllu; J Honkanen; R Puska; M Mehto; A Hassi; T H Teeri; Merike Kelve; P Seppänen; Mart Saarma
Transgenic potato plants expressing mammalian 2'-5' oligoadenylate synthetase are protected from potato virus X infection under field conditions.
Bio/technology (Nature Publishing Company) 1993;11(9):1048-52.
1990: Elena N Kalinichenko; Tatiana L Podkopaeva; Merike Kelve; Mart Saarma; Igor Mikhailopulo
3'-Fluoro-3'-deoxy analogs of 2-5A 5'-monophosphate: binding to 2-5A-dependent endoribonuclease and susceptibility to (2'-5')phosphodiesterase degradation.
Biochemical and biophysical research communications 1990;167(1):20-6.