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Brent Kendrick

Research Profile

Chemicals & Drugs

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Protein Folding

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Protein Denaturation

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TOP 3
John R Alford; Stanley C Kwok; Jennifer N Roberts; Deborah S Wuttke; Brent S Kendrick; John F Carpenter; Theodore W Randolph
High concentration formulations of recombinant human interleukin-1 receptor antagonist: I. Physical characterization.
John R Alford; Brent S Kendrick; John F Carpenter; Theodore W Randolph
High concentration formulations of recombinant human interleukin-1 receptor antagonist: II. Aggregation kinetics.
John R Alford; Brent S Kendrick; John F Carpenter; Theodore W Randolph
Measurement of the second osmotic virial coefficient for protein solutions exhibiting monomer-dimer equilibrium.

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All Publications

2008: John R Alford; Stanley C Kwok; Jennifer N Roberts; Deborah S Wuttke; Brent S Kendrick; John F Carpenter; Theodore W Randolph
High concentration formulations of recombinant human interleukin-1 receptor antagonist: I. Physical characterization.
Journal of pharmaceutical sciences 2008;97(8):3035-50.
2008: John R Alford; Brent S Kendrick; John F Carpenter; Theodore W Randolph
High concentration formulations of recombinant human interleukin-1 receptor antagonist: II. Aggregation kinetics.
Journal of pharmaceutical sciences 2008;97(8):3005-21.
2008: John R Alford; Brent S Kendrick; John F Carpenter; Theodore W Randolph
Measurement of the second osmotic virial coefficient for protein solutions exhibiting monomer-dimer equilibrium.
Analytical biochemistry 2008;377(2):128-33.
2007: Matthew B Seefeldt; Chris Crouch; Brent S Kendrick; Theodore W Randolph
Specific volume and adiabatic compressibility measurements of native and aggregated recombinant human interleukin-1 receptor antagonist: density differences enable pressure-modulated refolding.
Biotechnology and bioengineering 2007;98(2):476-85.
2007: Regina M Murphy; Brent S Kendrick
Protein misfolding and aggregation.
Biotechnology progress 2007;23(3):548-52.
2007: John P Gabrielson; Theodore W Randolph; Brent S Kendrick; Michael R Stoner
Sedimentation velocity analytical ultracentrifugation and SEDFIT/c(s): limits of quantitation for a monoclonal antibody system.
Analytical biochemistry 2007;361(1):24-30.
2005: Eva Y Chi; Brent S Kendrick; John F Carpenter; Theodore W Randolph
Population balance modeling of aggregation kinetics of recombinant human interleukin-1 receptor antagonist.
Journal of pharmaceutical sciences 2005;94(12):2735-48.
2004: Michael R Stoner; Norm Fischer; Lori Nixon; Scott Buckel; Mark Benke; Fred Austin; Theodore W Randolph; Brent S Kendrick
Protein-solute interactions affect the outcome of ultrafiltration/diafiltration operations.
Journal of pharmaceutical sciences 2004;93(9):2332-42.
2003: Yong-Sung Kim; LaToya S Jones; Aichun Dong; Brent S Kendrick; Byeong S Chang; Mark C Manning; Theodore W Randolph; John F Carpenter
Effects of sucrose on conformational equilibria and fluctuations within the native-state ensemble of proteins.
Protein science : a publication of the Protein Society 2003;12(6):1252-61.
2003: Eva Y Chi; Sampathkumar Krishnan; Brent S Kendrick; Byeong S Chang; John F Carpenter; Theodore W Randolph
Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony-stimulating factor.
Protein science : a publication of the Protein Society 2003;12(5):903-13.
2003: Sampathkumar Krishnan; Eva Y Chi; Stephen J Wood; Brent S Kendrick; Cynthia Li; William Garzon-Rodriguez; Jette Wypych; Theodore W Randolph; Linda O Narhi; Anja Leona Biere; Martin Citron; John F Carpenter
Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease alpha-synuclein fibrillogenesis.
Biochemistry 2003;42(3):829-37.
2002: Brent S Kendrick; Tiansheng Li; Byeong S Chang
Physical stabilization of proteins in aqueous solution.
Pharmaceutical biotechnology 2002;13():61-84.
2001: Brent S Kendrick; Bruce A Kerwin; Byeong S Chang; John Philo
Online size-exclusion high-performance liquid chromatography light scattering and differential refractometry methods to determine degree of polymer conjugation to proteins and protein-protein or protein-ligand association states.
Analytical biochemistry 2001;299(2):136-46.
2001: Jeffrey L Cleland; XM Lam; Brent S Kendrick; J Yang; TH Yang; D Overcashier; D Brooks; C Hsu; John F Carpenter
A specific molar ratio of stabilizer to protein is required for storage stability of a lyophilized monoclonal antibody.
Journal of pharmaceutical sciences 2001;90(3):310-21.
1999: John F Carpenter; Brent S Kendrick; Byeong S Chang; Mark C Manning; Theodore W Randolph
Inhibition of stress-induced aggregation of protein therapeutics.
Methods in enzymology 1999;309():236-55.
1998: N Li; Brent S Kendrick; Mark C Manning; John F Carpenter; John G Duman
Secondary structure of antifreeze proteins from overwintering larvae of the beetle Dendroides canadensis.
Archives of biochemistry and biophysics 1998;360(1):25-32.
1998: Brent S Kendrick; John F Carpenter; Jeffrey L Cleland; Theodore W Randolph
A transient expansion of the native state precedes aggregation of recombinant human interferon-gamma.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14142-6.
1998: Brent S Kendrick; Jeffrey L Cleland; XM Lam; T Nguyen; Theodore W Randolph; Mark C Manning; John F Carpenter
Aggregation of recombinant human interferon gamma: kinetics and structural transitions.
Journal of pharmaceutical sciences 1998;87(9):1069-76.
1997: Aichun Dong; Brent S Kendrick; L Kreilgârd; JE Matsuura; Mark C Manning; John F Carpenter
Spectroscopic study of secondary structure and thermal denaturation of recombinant human factor XIII in aqueous solution.
Archives of biochemistry and biophysics 1997;347(2):213-20.
1997: Brent S Kendrick; Jeffrey D Meyer; JE Matsuura; John F Carpenter; Mark C Manning
Hydrophobic ion pairing as a method for enhancing structure and activity of lyophilized subtilisin BPN' suspended in isooctane.
Archives of biochemistry and biophysics 1997;347(1):113-8.
1997: Brent S Kendrick; Byeong S Chang; T Arakawa; B Peterson; Theodore W Randolph; Mark C Manning; John F Carpenter
Preferential exclusion of sucrose from recombinant interleukin-1 receptor antagonist: role in restricted conformational mobility and compaction of native state.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(22):11917-22.
1996: Byeong S Chang; Brent S Kendrick; John F Carpenter
Surface-induced denaturation of proteins during freezing and its inhibition by surfactants.
Journal of pharmaceutical sciences 1996;85(12):1325-30.
1996: Aichun Dong; Jeffrey D Meyer; Brent S Kendrick; Mark C Manning; John F Carpenter
Effect of secondary structure on the activity of enzymes suspended in organic solvents.
Archives of biochemistry and biophysics 1996;334(2):406-14.
1996: Jeffrey D Meyer; Brent S Kendrick; JE Matsuura; J A Ruth; Philip N Bryan; Mark C Manning
Generation of soluble and active subtilisin and alpha-chymotrypsin in organic solvents via hydrophobic ion pairing.
International journal of peptide and protein research 1996;47(3):177-81.
1996: Brent S Kendrick; Aichun Dong; SD Allison; Mark C Manning; John F Carpenter
Quantitation of the area of overlap between second-derivative amide I infrared spectra to determine the structural similarity of a protein in different states.
Journal of pharmaceutical sciences 1996;85(2):155-8.