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Mathias Bähr

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Jan C Koch; Paul Lingor; Uwe Michel; Aleksandra Shypitsyna; Gonzalo P Solis; Mathias Bähr; Vsevolod Bodrikov; Deana Haralampieva; Lars Tönges; Claudia A O Stuermer
Upregulation of reggie-1/flotillin-2 promotes axon regeneration in the rat optic nerve in vivo and neurite growth in vitro.
Lars Tönges; Jochen H Weishaupt; Éva M Szego; Kim A Saal; Lars Tatenhorst; Mathias Bähr; Tobias Frank; Jan C Koch; Paul Lingor
Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease.
Kurt-Wolfram Sühs; Mathias Bähr; Diana Bittersohl; Christoph Ciupka; Klaus Fassbender; Anke Görlitz; Andrea Hassenstein; Christoph Heesen; Katharina Hein; Reinhard Hilgers; Barbara Käsmann-Kellner; Panagiotis Papanagiotou; Wolfgang Reith; Cordula Restemeyer; Muriel B Sättler; Nina Schäffler; Kerstin Scholz; Berthold Seitz; Ricarda Diem
A randomized, double-blind, phase 2 study of erythropoietin in optic neuritis.

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All Publications

2013: Jan C Koch; Paul Lingor; Uwe Michel; Aleksandra Shypitsyna; Gonzalo P Solis; Mathias Bähr; Vsevolod Bodrikov; Deana Haralampieva; Lars Tönges; Claudia A O Stuermer
Upregulation of reggie-1/flotillin-2 promotes axon regeneration in the rat optic nerve in vivo and neurite growth in vitro.
Neurobiology of disease 2013;51():168-76.
2012: Lars Tönges; Jochen H Weishaupt; Éva M Szego; Kim A Saal; Lars Tatenhorst; Mathias Bähr; Tobias Frank; Jan C Koch; Paul Lingor
Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease.
Brain : a journal of neurology 2012;135(Pt 11):3355-70.
2012: Kurt-Wolfram Sühs; Mathias Bähr; Diana Bittersohl; Christoph Ciupka; Klaus Fassbender; Anke Görlitz; Andrea Hassenstein; Christoph Heesen; Katharina Hein; Reinhard Hilgers; Barbara Käsmann-Kellner; Panagiotis Papanagiotou; Wolfgang Reith; Cordula Restemeyer; Muriel B Sättler; Nina Schäffler; Kerstin Scholz; Berthold Seitz; Ricarda Diem
A randomized, double-blind, phase 2 study of erythropoietin in optic neuritis.
Annals of neurology 2012;72(2):199-210.
2012: Paul Lingor; Lars Tönges; Jan C Koch; Mathias Bähr
Axonal degeneration as a therapeutic target in the CNS.
Cell and tissue research 2012;349(1):289-311.
2012: Thorsten R Doeppner; Ayman ElAli; Tobias A S Ewert; Bernd Giebel; Dirk M Hermann; Josephine Herz; Anna-Kristin Ludwig; Florian Nagel; Lars Tönges; Jens Weise; Anil Zechariah; Gunnar P H Dietz; Mathias Bähr
Transduction of neural precursor cells with TAT-heat shock protein 70 chaperone: therapeutic potential against ischemic stroke after intrastriatal and systemic transplantation.
Stem cells (Dayton, Ohio) 2012;30(6):1297-310.
2012: Tobias Frank; Bettina Göricke; Florian Klinker; Rico Laage; David Liebetanz; Fred Lühder; Hartmud Neurath; Armin Schneider; Mathias Bähr; Herbert Desel; Björn H Falkenburger; Jochen H Weishaupt
Pegylated granulocyte colony-stimulating factor conveys long-term neuroprotection and improves functional outcome in a model of Parkinson's disease.
Brain : a journal of neurology 2012;135(Pt 6):1914-25.
2012: Jan Liman; Kevin Rostasy; Andreas Wellmer; Mathias Bähr; Pawel Kermer
Transcranial ultrasound in neurodegeneration with brain iron accumulation (NBIA).
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 2012;16(2):175-8.
2012: René Günther; Jan C Koch; Paul Lingor; Martin Suhr; Mathias Bähr; Lars Tönges
Clinical testing and spinal cord removal in a mouse model for amyotrophic lateral sclerosis (ALS).
Journal of visualized experiments : JoVE 2012;(61):.
2012: Katharina Hein; Benedikt Kretzschmar; Katharina Lange; Muriel B Sättler; Ricarda Diem; Ivana Gadjanski; Mathias Bähr
An optical coherence tomography study on degeneration of retinal nerve fiber layer in rats with autoimmune optic neuritis.
Investigative ophthalmology & visual science 2012;53(1):157-63.
2011: Jan C Koch; Mathias Bähr; Johanna Knöferle; Uwe Michel; Lars Tönges; Paul Lingor
Imaging of rat optic nerve axons in vivo.
Nature protocols 2011;6(12):1887-96.
2011: Lars Tönges; Veronique Planchamp; Mathias Bähr; Thomas Herdegen; Jan-Christoph Koch; Paul Lingor
JNK isoforms differentially regulate neurite growth and regeneration in dopaminergic neurons in vitro.
Journal of molecular neuroscience : MN 2011;45(2):284-93.
2011: Jan C Koch; Paul Lingor; Mathias Bähr; Elisabeth Barski; Uwe Michel
Plasmids containing NRSE/RE1 sites enhance neurite outgrowth of retinal ganglion cells via sequestration of REST independent of NRSE dsRNA expression.
The FEBS journal 2011;278(18):3472-83.
2011: Petranka Krumova; Sebastian Kügler; Frauke Melchior; Erik Meulmeester; Marilyn Tirard; Henning Urlaub; Mathias Bähr; Guillaume Bossis; Manuel Garrido; He-Hsuan Hsiao; Markus Zweckstetter; Jochen H Weishaupt
Sumoylation inhibits alpha-synuclein aggregation and toxicity.
The Journal of cell biology 2011;194(1):49-60.
2011: Ivana Gadjanski; Katharina Hein; Muriel B Sättler; Sarah K Williams; Mathias Bähr; Ricarda Diem
Correlation of optical coherence tomography with clinical and histopathological findings in experimental autoimmune uveoretinitis.
Experimental eye research 2011;93(1):82-90.
2011: Lars Tönges; Thomas Ostendorf; Fabienne Lamballe; Matthieu Genestine; Rosanna Dono; Jan-Christoph Koch; Mathias Bähr; Flavio Maina; Paul Lingor
Hepatocyte growth factor protects retinal ganglion cells by increasing neuronal survival and axonal regeneration in vitro and in vivo.
Journal of neurochemistry 2011;117(5):892-903.
2011: Thorsten R Doeppner; Britta Kaltwasser; Ayman ElAli; Anil Zechariah; Dirk M Hermann; Mathias Bähr
Acute hepatocyte growth factor treatment induces long-term neuroprotection and stroke recovery via mechanisms involving neural precursor cell proliferation and differentiation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(5):1251-62.
2011: Christian R Rau; Katharina Hein; Muriel B Sättler; Benedikt Kretzschmar; Carina Hillgruber; Bradford L McRae; Ricarda Diem; Mathias Bähr
Anti-inflammatory effects of FTY720 do not prevent neuronal cell loss in a rat model of optic neuritis.
The American journal of pathology 2011;178(4):1770-81.
2011: Lars Tönges; Mathias Bähr; Jan-Christoph Koch; Paul Lingor
ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.
Frontiers in molecular neuroscience 2011;4():39.
2011: Jan Liman; Philipp von Gottberg; Mathias Bähr; Pawel Kermer
Femoral nerve palsy caused by ileopectineal bursitis after total hip replacement: a case report.
Journal of medical case reports 2011;5():190.
2010: Thorsten R Doeppner; Mimount El Aanbouri; Gunnar P H Dietz; Jens Weise; Sönke Schwarting; Mathias Bähr
Transplantation of TAT-Bcl-xL-transduced neural precursor cells: long-term neuroprotection after stroke.
Neurobiology of disease 2010;40(1):265-76.
2010: Mathias Bähr
Special issue on multiple sclerosis.
Experimental neurology 2010;225(1):1.
2010: Muriel B Sättler; Mathias Bähr
Future neuroprotective strategies.
Experimental neurology 2010;225(1):40-7.
2010: Florian B Freimann; Olaf Crome; Zinayida Shevtsova; Mathias Bähr; Sebastian Kügler
Evaluation of long-term upregulation of Calbindin D28K as a preventive approach for ischaemic stroke.
International journal of stroke : official journal of the International Stroke Society 2010;5(4):319-20.
2010: Zinayida Shevtsova; Manuel Garrido; Jochen H Weishaupt; Paul Saftig; Mathias Bähr; Fred Lühder; Sebastian Kügler
CNS-expressed cathepsin D prevents lymphopenia in a murine model of congenital neuronal ceroid lipofuscinosis.
The American journal of pathology 2010;177(1):271-9.
2010: Jan C Koch; Mathias Bähr; Johanna Knöferle; Thomas Ostendorf; Lars Tönges; Paul Lingor
Acute axonal degeneration in vivo is attenuated by inhibition of autophagy in a calcium-dependent manner.
Autophagy 2010;6(5):658-9.
2010: Johanna Knöferle; Sanja Ramljak; Jan C Koch; Lars Tönges; Abdul R Asif; Uwe Michel; Fred S Wouters; Stephan Heermann; Kerstin Krieglstein; Inga Zerr; Mathias Bähr; Paul Lingor
TGF-beta 1 enhances neurite outgrowth via regulation of proteasome function and EFABP.
Neurobiology of disease 2010;38(3):395-404.
2010: Thorsten R Doeppner; Gunnar P H Dietz; Jens Weise; Mathias Bähr
Protection of hippocampal neurogenesis by TAT-Bcl-x(L) after cerebral ischemia in mice.
Experimental neurology 2010;223(2):548-56.
2010: Johanna Knöferle; Jan C Koch; Thomas Ostendorf; Uwe Michel; Véronique Planchamp; Polya Vutova; Lars Tönges; Christine Stadelmann; Wolfgang Brück; Mathias Bähr; Paul Lingor
Mechanisms of acute axonal degeneration in the optic nerve in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(13):6064-9.
2010: Sebastian Deeg; Mathias Gralle; Kamila Sroka; Mathias Bähr; Fred Silvester Wouters; Pawel Kermer
BAG1 restores formation of functional DJ-1 L166P dimers and DJ-1 chaperone activity.
The Journal of cell biology 2010;188(4):505-13.
2009: Christina Bermel; Lars Tönges; Veronique Planchamp; Frank Gillardon; Jochen H Weishaupt; Gunnar P H Dietz; Mathias Bähr; Paul Lingor
Combined inhibition of Cdk5 and ROCK additively increase cell survival, but not the regenerative response in regenerating retinal ganglion cells.
Molecular and cellular neurosciences 2009;42(4):427-37.
2009: Kamila Sroka; Aaron Voigt; Sebastian Deeg; John C Reed; Jörg B Schulz; Mathias Bähr; Pawel Kermer
BAG1 modulates huntingtin toxicity, aggregation, degradation, and subcellular distribution.
Journal of neurochemistry 2009;111(3):801-7.
2009: Ivana Gadjanski; Susann Boretius; Sarah K Williams; Paul Lingor; Johanna Knöferle; Muriel B Sättler; Richard Fairless; Sonja Hochmeister; Kurt-Wolfram Sühs; Thomas Michaelis; Jens Frahm; Maria K Storch; Mathias Bähr; Ricarda Diem
Role of n-type voltage-dependent calcium channels in autoimmune optic neuritis.
Annals of neurology 2009;66(1):81-93.
2009: Florian Nagel; Mathias Bähr; Gunnar P H Dietz
Tyrosine hydroxylase-positive amacrine interneurons in the mouse retina are resistant against the application of various parkinsonian toxins.
Brain research bulletin 2009;79(5):303-9.
2009: Thorsten R Doeppner; Florian Nagel; Gunnar P H Dietz; Jens Weise; Lars Tönges; Sönke Schwarting; Mathias Bähr
TAT-Hsp70-mediated neuroprotection and increased survival of neuronal precursor cells after focal cerebral ischemia in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(6):1187-96.
2009: Sandra Ebert; Sara M Pilgram; Mathias Bähr; Pawel Kermer
Bilateral ophthalmoplegia due to symmetric cavernous sinus metastasis from gastric adenocarcinoma.
Journal of the neurological sciences 2009;279(1-2):106-8.
2009: Thorsten R Doeppner; Gunnar P H Dietz; Mimount El Aanbouri; Joachim Gerber; Otto W Witte; Mathias Bähr; Jens Weise
TAT-Bcl-x(L) improves survival of neuronal precursor cells in the lesioned striatum after focal cerebral ischemia.
Neurobiology of disease 2009;34(1):87-94.
2009: Tobias Frank; Johannes C M Schlachetzki; Bettina Göricke; Katrin Meuer; Gundula Rohde; Gunnar P H Dietz; Mathias Bähr; Armin Schneider; Jochen H Weishaupt
Both systemic and local application of granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy.
BMC neuroscience 2009;10():49.
2008: Gundula Rohde; Pawel Kermer; John C Reed; Mathias Bähr; Jochen H Weishaupt
Neuron-specific overexpression of the co-chaperone Bcl-2-associated athanogene-1 in superoxide dismutase 1(G93A)-transgenic mice.
Neuroscience 2008;157(4):844-9.
2008: Muriel B Sättler; Sarah K Williams; Clemens Neusch; Markus Otto; Jens R Pehlke; Mathias Bähr; Ricarda Diem
Flupirtine as neuroprotective add-on therapy in autoimmune optic neuritis.
The American journal of pathology 2008;173(5):1496-507.
2008: Véronique Planchamp; Christina Bermel; Lars Tönges; Thomas Ostendorf; Sebastian Kügler; John C Reed; Pawel Kermer; Mathias Bähr; Paul Lingor
BAG1 promotes axonal outgrowth and regeneration in vivo via Raf-1 and reduction of ROCK activity.
Brain : a journal of neurology 2008;131(Pt 10):2606-19.
2008: Sönke Schwarting; Sara Litwak; Wenlin Hao; Mathias Bähr; Jens Weise; Harald Neumann
Hematopoietic stem cells reduce postischemic inflammation and ameliorate ischemic brain injury.
Stroke; a journal of cerebral circulation 2008;39(10):2867-75.
2008: Ricarda Diem; Iris Demmer; Susann Boretius; Doron Merkler; Barthel Schmelting; Sarah K Williams; Muriel B Sättler; Mathias Bähr; Thomas Michaelis; Jens Frahm; Wolfgang Brück; Eberhard Fuchs
Autoimmune optic neuritis in the common marmoset monkey: comparison of visual evoked potentials with MRI and histopathology.
Investigative ophthalmology & visual science 2008;49(8):3707-14.
2008: Florian Nagel; Christoph P Dohm; Mathias Bähr; Fred S Wouters; Gunnar P H Dietz
Quantitative evaluation of chaperone activity and neuroprotection by different preparations of a cell-penetrating Hsp70.
Journal of neuroscience methods 2008;171(2):226-32.
2008: Tanja Heller; Ingelore Nagel; Bettina Ehrlich; Mathias Bähr; Herwig M Strik
Automated cerebrospinal fluid cytology.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2008;30(3):139-44.
2008: Susann Boretius; Ivana Gadjanski; Iris Demmer; Mathias Bähr; Ricarda Diem; Thomas Michaelis; Jens Frahm
MRI of optic neuritis in a rat model.
NeuroImage 2008;41(2):323-34.
2008: Katharina Hein Née Maier; Anushka Köhler; Ricarda Diem; Muriel B Sättler; Iris Demmer; Peter Lange; Mathias Bähr; Markus Otto
Biological markers for axonal degeneration in CSF and blood of patients with the first event indicative for multiple sclerosis.
Neuroscience letters 2008;436(1):72-6.
2008: Jens Schmidt; Konstanze Barthel; Arne Wrede; Mohammad Salajegheh; Mathias Bähr; Marinos C Dalakas
Interrelation of inflammation and APP in sIBM: IL-1 beta induces accumulation of beta-amyloid in skeletal muscle.
Brain : a journal of neurology 2008;131(Pt 5):1228-40.
2008: Florian Nagel; Björn H Falkenburger; Lars Tönges; Sebastian Kowsky; Charlotte Pöppelmeyer; Jörg B Schulz; Mathias Bähr; Gunnar P H Dietz
Tat-Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson's disease.
Journal of neurochemistry 2008;105(3):853-64.
2008: Jan Liman; Lena Faida; Christoph P Dohm; John C Reed; Mathias Bähr; Pawel Kermer
Subcellular distribution affects BAG1 function.
Brain research 2008;1198():21-6.
2008: Gunnar P H Dietz; Kerstin V Stockhausen; Birgit Dietz; Björn H Falkenburger; Paola Valbuena; Felipe Opazo; Paul Lingor; Katrin Meuer; Jochen H Weishaupt; Jörg B Schulz; Mathias Bähr
Membrane-permeable Bcl-xL prevents MPTP-induced dopaminergic neuronal loss in the substantia nigra.
Journal of neurochemistry 2008;104(3):757-65.
2008: Sundar Ganesan; Gundula Rohde; K Eckermann; K Sroka; M K E Schaefer; Christoph P Dohm; Pawel Kermer; G Haase; Fred S Wouters; Mathias Bähr; Jochen H Weishaupt
Mutant SOD1 detoxification mechanisms in intact single cells.
Cell death and differentiation 2008;15(2):312-21.
2008: Jens Weise; Thorsten R Doeppner; Tilo Müller; Arne Wrede; Walter Schulz-Schaeffer; Inga Zerr; Otto W Witte; Mathias Bähr
Overexpression of cellular prion protein alters postischemic Erk1/2 phosphorylation but not Akt phosphorylation and protects against focal cerebral ischemia.
Restorative neurology and neuroscience 2008;26(1):57-64.
2008: C P Dohm; Pawel Kermer; Mathias Bähr
Aggregopathy in neurodegenerative diseases: mechanisms and therapeutic implication.
Neuro-degenerative diseases 2008;5(6):321-38.
2008: Paul Lingor; Lars Tönges; Nicole Pieper; Christina Bermel; Elisabeth Barski; Veronique Planchamp; Mathias Bähr
ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells.
Brain : a journal of neurology 2008;131(Pt 1):250-63.
2008: Muriel B Sättler; Mauro Togni; Ivana Gadjanski; Kurt-Wolfram Sühs; Nadine Meyer; Mathias Bähr; Ricarda Diem
Strain-specific susceptibility for neurodegeneration in a rat model of autoimmune optic neuritis.
Journal of neuroimmunology 2008;193(1-2):77-86.
2008: Haikun Shi; Daniel Patschan; Gunnar P H Dietz; Mathias Bähr; Matthew D Plotkin; Michael S Goligorsky
Glial cell line-derived neurotrophic growth factor increases motility and survival of cultured mesenchymal stem cells and ameliorates acute kidney injury.
American journal of physiology. Renal physiology 2008;294(1):F229-35.
2007: Paul Lingor; Mathias Bähr
Targeting neurological disease with RNAi.
Molecular bioSystems 2007;3(11):773-80.
2007: Paul Lingor; Nicole Teusch; Katrin Schwarz; Reinhold Mueller; Helmut Mack; Mathias Bähr; Bernhard K Mueller
Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo.
Journal of neurochemistry 2007;103(1):181-9.
2007: Gunnar P H Dietz; Birgit Dietz; Mathias Bähr
Bcl-xL protects cerebellar granule neurons against the late phase, but not against the early phase of glutamate-induced cell death.
Brain research 2007;1164():136-41.
2007: Herwig M Strik; Katharina Schmidt; Paul Lingor; Lars Tönges; Wilfried Kugler; Mirko Nitsche; Gabriel A Rabinovich; Mathias Bähr
Galectin-1 expression in human glioma cells: modulation by ionizing radiation and effects on tumor cell proliferation and migration.
Oncology reports 2007;18(2):483-8.
2007: Alessandro Esposito; Christoph P Dohm; Mathias Bähr; Fred S Wouters
Unsupervised fluorescence lifetime imaging microscopy for high content and high throughput screening.
Molecular & cellular proteomics : MCP 2007;6(8):1446-54.
2007: Daniele Peroni; Alessandro Negro; Mathias Bähr; Gunnar P H Dietz
Intracellular delivery of Neuroglobin using HIV-1 TAT protein transduction domain fails to protect against oxygen and glucose deprivation.
Neuroscience letters 2007;421(2):110-4.
2007: Olaf Crome; Thorsten R Doeppner; Sönke Schwarting; Barbara Müller; Mathias Bähr; Jens Weise
Enhanced poly(ADP-ribose) polymerase-1 activation contributes to recombinant tissue plasminogen activator-induced aggravation of ischemic brain injury in vivo.
Journal of neuroscience research 2007;85(8):1734-43.
2007: Alessandro Esposito; Christoph P Dohm; Pawel Kermer; Mathias Bähr; Fred S Wouters
alpha-Synuclein and its disease-related mutants interact differentially with the microtubule protein tau and associate with the actin cytoskeleton.
Neurobiology of disease 2007;26(3):521-31.
2007: Clemens Neusch; Mathias Bähr; Christiane Schneider-Gold
Glia cells in amyotrophic lateral sclerosis: new clues to understanding an old disease?
Muscle & nerve 2007;35(6):712-24.
2007: Clemens Neusch; J Senderek; T Eggermann; E Elolff; Mathias Bähr; Christiane Schneider-Gold
Mitofusin 2 gene mutation (R94Q) causing severe early-onset axonal polyneuropathy (CMT2A).
European journal of neurology : the official journal of the European Federation of Neurological Societies 2007;14(5):575-7.
2007: David Liebetanz; Paul Christian Baier; Walter Paulus; Katrin Meuer; Mathias Bähr; Jochen H Weishaupt
A highly sensitive automated complex running wheel test to detect latent motor deficits in the mouse MPTP model of Parkinson's disease.
Experimental neurology 2007;205(1):207-13.
2007: Katrin Meuer; I E Suppanz; Paul Lingor; Veronique Planchamp; Bettina Göricke; Lars Fichtner; Gerhard H Braus; Gunnar P H Dietz; S Jakobs; Mathias Bähr; Jochen H Weishaupt
Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis.
Cell death and differentiation 2007;14(4):651-61.
2007: Lars Tönges; Johannes C M Schlachetzki; Jochen H Weishaupt; Mathias Bähr
Hematopoietic cytokines--on the verge of conquering neurology.
Current molecular medicine 2007;7(2):157-70.
2007: Katharina Maier; Doron Merkler; Joachim Gerber; Naimeh Taheri; Antje V Kuhnert; Sarah K Williams; Clemens Neusch; Mathias Bähr; Ricarda Diem
Multiple neuroprotective mechanisms of minocycline in autoimmune CNS inflammation.
Neurobiology of disease 2007;25(3):514-25.
2007: Ricarda Diem; Muriel B Sättler; Mathias Bähr
Neurodegeneration and -protection in autoimmune CNS inflammation.
Journal of neuroimmunology 2007;184(1-2):27-36.
2007: Gunnar P H Dietz; Mathias Bähr
Synthesis of cell-penetrating peptides and their application in neurobiology.
Methods in molecular biology (Clifton, N.J.) 2007;399():181-98.
2006: Jochen H Weishaupt; Claudia Bartels; Esther Pölking; Jeannine Dietrich; Gundula Rohde; Burkhard Poeggeler; Nina Mertens; Swetlana Sperling; Matthias Bohn; Gerald Hüther; Armin Schneider; Alfred Bach; Anna-Leena Sirén; Rüdiger Hardeland; Mathias Bähr; Klaus-Armin Nave; Hannelore Ehrenreich
Reduced oxidative damage in ALS by high-dose enteral melatonin treatment.
Journal of pineal research 2006;41(4):313-23.
2006: Melanie Kaiser; Iris Maletzki; Swen Hülsmann; Bettina Holtmann; Walter Schulz-Schaeffer; Frank Kirchhoff; Mathias Bähr; Clemens Neusch
Progressive loss of a glial potassium channel (KCNJ10) in the spinal cord of the SOD1 (G93A) transgenic mouse model of amyotrophic lateral sclerosis.
Journal of neurochemistry 2006;99(3):900-12.
2006: Anat Nitzan; Pawel Kermer; Anat Shirvan; Mathias Bähr; Ari Barzilai; Arieh S Solomon
Examination of cellular and molecular events associated with optic nerve axotomy.
Glia 2006;54(6):545-56.
2006: Z Shevtsova; Ibrahim Malik; Manuel Garrido; Ulrike Schöll; Mathias Bähr; Sebastian Kügler
Potentiation of in vivo neuroprotection by BclX(L) and GDNF co-expression depends on post-lesion time in deafferentiated CNS neurons.
Gene therapy 2006;13(22):1569-78.
2006: Katharina Maier; Antje V Kuhnert; Naimeh Taheri; Muriel B Sättler; Maria K Storch; Sarah K Williams; Mathias Bähr; Ricarda Diem
Effects of glatiramer acetate and interferon-beta on neurodegeneration in a model of multiple sclerosis: a comparative study.
The American journal of pathology 2006;169(4):1353-64.
2006: Muriel B Sättler; Iris Demmer; Sarah K Williams; Katharina Maier; Doron Merkler; Ivana Gadjanski; Christine Stadelmann; Mathias Bähr; Ricarda Diem
Effects of interferon-beta-1a on neuronal survival under autoimmune inflammatory conditions.
Experimental neurology 2006;201(1):172-81.
2006: Stephan Hermening; Sebastian Kügler; Mathias Bähr; Stefan Isenmann
Improved high-capacity adenoviral vectors for high-level neuron-restricted gene transfer to the CNS.
Journal of virological methods 2006;136(1-2):30-7.
2006: Lars Tönges; Paul Lingor; Roman Egle; Gunnar P H Dietz; Alfred Fahr; Mathias Bähr
Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons.
RNA (New York, N.Y.) 2006;12(7):1431-8.
2006: Gunnar P H Dietz; Birgit Dietz; Mathias Bähr
Bcl-x(L) increases axonal numbers but not axonal elongation from rat retinal explants.
Brain research bulletin 2006;70(2):117-23.
2006: Nicolas Pietrancosta; Anice Moumen; Rosanna Dono; Paul Lingor; Veronique Planchamp; Fabienne Lamballe; Mathias Bähr; Jean-Louis Kraus; Flavio Maina
Imino-tetrahydro-benzothiazole derivatives as p53 inhibitors: discovery of a highly potent in vivo inhibitor and its action mechanism.
Journal of medicinal chemistry 2006;49(12):3645-52.
2006: Richard S Hotchkiss; Kevin W McConnell; Kristin E Bullok; Christopher G Davis; Katherine C Chang; Steven J Schwulst; Jeffrey C Dunne; Gunnar P H Dietz; Mathias Bähr; Jonathan E McDunn; Irene E Karl; Tracey H Wagner; J Perren Cobb; Craig M Coopersmith; David Piwnica-Worms
TAT-BH4 and TAT-Bcl-xL peptides protect against sepsis-induced lymphocyte apoptosis in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(9):5471-7.
2006: Jens Weise; Raoul Sandau; Sönke Schwarting; Olaf Crome; Arne Wrede; Walter Schulz-Schaeffer; Inga Zerr; Mathias Bähr
Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury.
Stroke; a journal of cerebral circulation 2006;37(5):1296-300.
2006: Katrin Meuer; Claudia Pitzer; Peter Teismann; Carola Krüger; Bettina Göricke; Rico Laage; Paul Lingor; Kerstin Peters; Johannes C M Schlachetzki; Kazuto Kobayashi; Gunnar P H Dietz; Daniela Weber; Boris Ferger; Wolf-Rüdiger Schäbitz; Alfred Bach; Jörg B Schulz; Mathias Bähr; Armin Schneider; Jochen H Weishaupt
Granulocyte-colony stimulating factor is neuroprotective in a model of Parkinson's disease.
Journal of neurochemistry 2006;97(3):675-86.
2006: Gunnar P H Dietz; Paoloa C Valbuena; Birgit Dietz; Katrin Meuer; Patrick Müeller; Jochen H Weishaupt; Mathias Bähr
Application of a blood-brain-barrier-penetrating form of GDNF in a mouse model for Parkinson's disease.
Brain research 2006;1082(1):61-6.
2006: Z Shevtsova; J M I Malik; Uwe Michel; Ulrike Schöll; Mathias Bähr; Sebastian Kügler
Evaluation of epitope tags for protein detection after in vivo CNS gene transfer.
The European journal of neuroscience 2006;23(8):1961-9.
2006: Christelle Guégan; Jérôme Braudeau; Cécile Couriaud; Gunnar P H Dietz; Pierre Lacombe; Mathias Bähr; Marika Nosten-Bertrand; Brigitte Onténiente
PTD-XIAP protects against cerebral ischemia by anti-apoptotic and transcriptional regulatory mechanisms.
Neurobiology of disease 2006;22(1):177-86.
2006: S Schilling; Ralf A Linker; F B König; Michael Koziolek; Mathias Bähr; Gerhard A Müller; W Paulus; J Gärtner; Wolfgang Brück; A Chan; Ralf Gold
[Plasma exchange therapy for steroid-unresponsive multiple sclerosis relapses: clinical experience with 16 patients].
Der Nervenarzt 2006;77(4):430-8.
2006: Ibrahim Malik; Manuel Garrido; Mathias Bähr; Sebastian Kügler; Uwe Michel
Comparison of test systems for RNAinterference.
Biochemical and biophysical research communications 2006;341(1):245-53.
2006: Herwig M Strik; Petra Hülper; Bernhard Erdlenbruch; Jessica Meier; Alexandra Kowalewski; Bernhard Hemmerlein; Ralf Gold; Mathias Bähr
Models of monocytic invasion into glioma cell aggregates.
Anticancer research 2006;26(2A):865-71.
2006: Pawel Kermer; Andreas Wellmer; Olaf Crome; Alexander Mohr; Michael Knauth; Mathias Bähr
Transcranial color-coded duplex sonography in suspected acute basilar artery occlusion.
Ultrasound in medicine & biology 2006;32(3):315-20.
2006: Michael Müller; Nestoras Papadopoulos; Michael Müller; Iris Maletzki; Stefan M Winter; Johannes Hirrlinger; Melanie Handschuh; Mathias Bähr; Diethelm W Richter; Frank Kirchhoff; Swen Hülsmann
Lack of the Kir4.1 channel subunit abolishes K+ buffering properties of astrocytes in the ventral respiratory group: impact on extracellular K+ regulation.
Journal of neurophysiology 2006;95(3):1843-52.
2006: Peter Ratzka; Johannes C M Schlachetzki; Mathias Bähr; Roland Nau
Varicella zoster virus cerebellitis in a 66-year-old patient without herpes zoster.
Lancet 2006;367(9505):182.
2006: Mathias Bähr; Paul Lingor
Brain repair: Experimental treatment strategies, neuroprotective and repair strategies in the lesioned adult CNS.
Advances in experimental medicine and biology 2006;557():148-63.
2006: Christoph P Dohm; Sandra Siedenberg; Jan Liman; Alessandro Esposito; Fred S Wouters; John C Reed; Mathias Bähr; Pawel Kermer
Bax inhibitor-1 protects neurons from oxygen-glucose deprivation.
Journal of molecular neuroscience : MN 2006;29(1):1-8.
2005: Gunnar P H Dietz; Mathias Bähr
Peptide-enhanced cellular internalization of proteins in neuroscience.
Brain research bulletin 2005;68(1-2):103-14.
2005: Ralf A Linker; Christine Stadelmann; Ricarda Diem; Mathias Bähr; Wolfgang Brück; Ralf Gold
[Recent advances in pathogenesis and therapy of multiple sclerosis].
Fortschritte der Neurologie-Psychiatrie 2005;73(12):715-27.
2005: Ricarda Diem; Naimeh Taheri; Gunnar P H Dietz; Antje V Kuhnert; Katharina Maier; Muriel B Sättler; Ivana Gadjanski; Doron Merkler; Mathias Bähr
HIV-Tat-mediated Bcl-XL delivery protects retinal ganglion cells during experimental autoimmune optic neuritis.
Neurobiology of disease 2005;20(2):218-26.
2005: Sandra Ebert; Gunnar P H Dietz; Tim Mitchell; Uwe Michel; Mathias Bähr; Roland Nau
Limited protection of TAT-Bcl-X(L) against pneumolysin-induced neuronal cell death.
Neuroscience letters 2005;384(3):349-53.
2005: Pawel Kermer; Mathias Bähr
[Programmed cell death in the retina. Molecular mechanisms and therapeutic strategies].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2005;102(7):674-8.
2005: Herwig M Strik; H Borchert; Carsten Fels; Michael Knauth; Otto Rienhoff; Mathias Bähr; Janko F Verhey
Three-dimensional reconstruction and volumetry of intracranial haemorrhage and its mass effect.
Neuroradiology 2005;47(6):417-24.
2005: Gunnar P H Dietz; Michael Schott; Monika Labes; Mathias Bähr
Expression of the protein inhibitor of nitric oxide synthase in the adult rat retina before and after optic nerve lesion.
Brain research. Molecular brain research 2005;136(1-2):118-24.
2005: Jan Liman; Sundar Ganesan; Christoph P Dohm; Stan Krajewski; John C Reed; Mathias Bähr; Fred S Wouters; Pawel Kermer
Interaction of BAG1 and Hsp70 mediates neuroprotectivity and increases chaperone activity.
Molecular and cellular biology 2005;25(9):3715-25.
2005: Muriel B Sättler; Ricarda Diem; Doron Merkler; Iris Demmer; Ina Boger; Christine Stadelmann; Mathias Bähr
Simvastatin treatment does not protect retinal ganglion cells from degeneration in a rat model of autoimmune optic neuritis.
Experimental neurology 2005;193(1):163-71.
2005: Jens Weise; Tobias Engelhorn; Arnd Dörfler; Stefanie Aker; Mathias Bähr; Andreas Hufnagel
Expression time course and spatial distribution of activated caspase-3 after experimental status epilepticus: contribution of delayed neuronal cell death to seizure-induced neuronal injury.
Neurobiology of disease 2005;18(3):582-90.
2005: J M I Malik; Z Shevtsova; Mathias Bähr; Sebastian Kügler
Long-term in vivo inhibition of CNS neurodegeneration by Bcl-XL gene transfer.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(3):373-81.
2005: Paul Lingor; Paulo D Koeberle; Sebastian Kügler; Mathias Bähr
Down-regulation of apoptosis mediators by RNAi inhibits axotomy-induced retinal ganglion cell death in vivo.
Brain : a journal of neurology 2005;128(Pt 3):550-8.
2005: Paul Lingor; Ulrike Schöll; Mathias Bähr; Sebastian Kügler
Functional applications of novel Semliki Forest virus vectors are limited by vector toxicity in cultures of primary neurons in vitro and in the substantia nigra in vivo.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2005;161(3):335-42.
2005: Ricarda Diem; Muriel B Sättler; Doron Merkler; Iris Demmer; Katharina Maier; Christine Stadelmann; Hannelore Ehrenreich; Mathias Bähr
Combined therapy with methylprednisolone and erythropoietin in a model of multiple sclerosis.
Brain : a journal of neurology 2005;128(Pt 2):375-85.
2005: Uwe Michel; Ibrahim Malik; Sandra Ebert; Mathias Bähr; Sebastian Kügler
Long-term in vivo and in vitro AAV-2-mediated RNA interference in rat retinal ganglion cells and cultured primary neurons.
Biochemical and biophysical research communications 2005;326(2):307-12.
2005: Jochen H Weishaupt; Nikolaj Klöcker; Mathias Bähr
Axotomy-induced early down-regulation of POU-IV class transcription factors Brn-3a and Brn-3b in retinal ganglion cells.
Journal of molecular neuroscience : MN 2005;26(1):17-25.
2005: Z Shevtsova; J M I Malik; Uwe Michel; Mathias Bähr; Sebastian Kügler
Promoters and serotypes: targeting of adeno-associated virus vectors for gene transfer in the rat central nervous system in vitro and in vivo.
Experimental physiology 2005;90(1):53-9.
2004: Stephan Hermening; Sebastian Kügler; Mathias Bähr; Stefan Isenmann
Increased protein expression from adenoviral shuttle plasmids and vectors by insertion of a small chimeric intron sequence.
Journal of virological methods 2004;122(1):73-7.
2004: Muriel B Sättler; Doron Merkler; Katharina Maier; Christine Stadelmann; H Ehrenreich; Mathias Bähr; Ricarda Diem
Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis.
Cell death and differentiation 2004;11 Suppl 2():S181-92.
2004: Jens Weise; Olaf Crome; Raoul Sandau; Walter Schulz-Schaeffer; Mathias Bähr; Inga Zerr
Upregulation of cellular prion protein (PrPc) after focal cerebral ischemia and influence of lesion severity.
Neuroscience letters 2004;372(1-2):146-50.
2004: Herwig M Strik; Annette Spreer; Holger Nagel; Sonja Jacob; Wolfram Jung; Bernd Kitze; Mathias Bähr
Clinical response following adjuvant Temozolomide in a patient with primary cerebral lymphoma.
Anticancer research 2004;24(6):4121-5.
2004: Katharina Maier; Christian R Rau; Maria K Storch; Muriel B Sättler; Iris Demmer; Robert Weissert; Naimeh Taheri; Antje V Kuhnert; Mathias Bähr; Ricarda Diem
Ciliary neurotrophic factor protects retinal ganglion cells from secondary cell death during acute autoimmune optic neuritis in rats.
Brain pathology (Zurich, Switzerland) 2004;14(4):378-87.
2004: Gunnar P H Dietz; Mathias Bähr
Delivery of bioactive molecules into the cell: the Trojan horse approach.
Molecular and cellular neurosciences 2004;27(2):85-131.
2004: Jens Weise; Sascha Kuschke; Mathias Bähr
Gender-specific risk of perioperative complications in carotid endarterectomy patients with contralateral carotid artery stenosis or occlusion.
Journal of neurology 2004;251(7):838-44.
2004: Ulkan Kilic; Ertugrul Kilic; Paul Lingor; Burak Yulug; Mathias Bähr
Rifampicin inhibits neurodegeneration in the optic nerve transection model in vivo and after 1-methyl-4-phenylpyridinium intoxication in vitro.
Acta neuropathologica 2004;108(1):65-8.
2004: Alexandra Kretz; Sebastian Kügler; Caroline J Happold; Mathias Bähr; Stefan Isenmann
Excess Bcl-XL increases the intrinsic growth potential of adult CNS neurons in vitro.
Molecular and cellular neurosciences 2004;26(1):63-74.
2004: Jochen H Weishaupt; Gundula Rohde; Esther Pölking; Anna-Leena Siren; Hannelore Ehrenreich; Mathias Bähr
Effect of erythropoietin axotomy-induced apoptosis in rat retinal ganglion cells.
Investigative ophthalmology & visual science 2004;45(5):1514-22.
2004: Muriel Hobom; Maria K Storch; Robert Weissert; Katharina Maier; Anand Radhakrishnan; Birgit Kramer; Mathias Bähr; Ricarda Diem
Mechanisms and time course of neuronal degeneration in experimental autoimmune encephalomyelitis.
Brain pathology (Zurich, Switzerland) 2004;14(2):148-57.
2004: Paulo D Koeberle; Mathias Bähr
Growth and guidance cues for regenerating axons: where have they gone?
Journal of neurobiology 2004;59(1):162-80.
2004: Paul Lingor; Uwe Michel; Ulrike Schöll; Mathias Bähr; Sebastian Kügler
Transfection of "naked" siRNA results in endosomal uptake and metabolic impairment in cultured neurons.
Biochemical and biophysical research communications 2004;315(4):1126-33.
2004: Burak Yulug; Ulkan Kilic; Ertugrul Kilic; Mathias Bähr
Rifampicin attenuates brain damage in focal ischemia.
Brain research 2004;996(1):76-80.
2004: Ulkan Kilic; Ertugrul Kilic; Gunnar P H Dietz; Mathias Bähr
The TAT protein transduction domain enhances the neuroprotective effect of glial-cell-line-derived neurotrophic factor after optic nerve transection.
Neuro-degenerative diseases 2004;1(1):44-9.
2004: Pawel Kermer; Jan Liman; Jochen H Weishaupt; Mathias Bähr
Neuronal apoptosis in neurodegenerative diseases: from basic research to clinical application.
Neuro-degenerative diseases 2004;1(1):9-19.
2004: Paul Lingor; Uwe Michel; Mathias Bähr
The long processes of short interfering RNAs--RNA interference and its implications in neuronal cells.
Neuro-degenerative diseases 2004;1(1):3-8.
2004: Ertugrul Kilic; Jochen H Weishaupt; Ulkan Kilic; Gundula Rohde; Burak Yulug; K Peters; Dirk M Hermann; Mathias Bähr
The superoxide dismutase1 (SOD1) G93A mutation does not promote neuronal injury after focal brain ischemia and optic nerve transection in mice.
Neuroscience 2004;128(2):359-64.
2003: Jochen H Weishaupt; Lothar Kussmaul; Philipp Grötsch; Armin Heckel; Gundula Rohde; H Romig; Mathias Bähr; Frank Gillardon
Inhibition of CDK5 is protective in necrotic and apoptotic paradigms of neuronal cell death and prevents mitochondrial dysfunction.
Molecular and cellular neurosciences 2003;24(2):489-502.
2003: Ricarda Diem; Muriel Hobom; Katharina Maier; Robert Weissert; Maria K Storch; Roman Meyer; Mathias Bähr
Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(18):6993-7000.
2003: Paul Lingor; Dirk von Boetticher; Mathias Bähr; Klaus Fassbender
Paraneoplastic polymyositis in recurring adrenal gland carcinoma.
Lancet neurology 2003;2(7):435-6.
2003: Jochen H Weishaupt; Ricarda Diem; Pawel Kermer; Stan Krajewski; John C Reed; Mathias Bähr
Contribution of caspase-8 to apoptosis of axotomized rat retinal ganglion cells in vivo.
Neurobiology of disease 2003;13(2):124-35.
2003: Jens Weise; Mathias Bähr; M Strayle-Batra; Wilhelm Küker
Detection of acute thalamo-mesencephalic infarction: diffusion abnormality precedes T2 hyperintensity.
Acta neurologica Scandinavica 2003;108(1):52-4.
2003: Sebastian Kügler; Paul Lingor; Ulrike Schöll; S Zolotukhin; Mathias Bähr
Differential transgene expression in brain cells in vivo and in vitro from AAV-2 vectors with small transcriptional control units.
Virology 2003;311(1):89-95.
2003: Ulkan Kilic; Ertugrul Kilic; Gunnar P H Dietz; Mathias Bähr
Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice.
Stroke; a journal of cerebral circulation 2003;34(5):1304-10.
2003: Ricarda Diem; Muriel Hobom; Philipp Grötsch; Birgit Kramer; Mathias Bähr
Interleukin-1 beta protects neurons via the interleukin-1 (IL-1) receptor-mediated Akt pathway and by IL-1 receptor-independent decrease of transmembrane currents in vivo.
Molecular and cellular neurosciences 2003;22(4):487-500.
2003: Jochen H Weishaupt; Clemens Neusch; Mathias Bähr
Cyclin-dependent kinase 5 (CDK5) and neuronal cell death.
Cell and tissue research 2003;312(1):1-8.
2003: Clemens Neusch; Jochen H Weishaupt; Mathias Bähr
Kir channels in the CNS: emerging new roles and implications for neurological diseases.
Cell and tissue research 2003;311(2):131-8.
2003: Sebastian Kügler; Ertugrul Kilic; Mathias Bähr
Human synapsin 1 gene promoter confers highly neuron-specific long-term transgene expression from an adenoviral vector in the adult rat brain depending on the transduced area.
Gene therapy 2003;10(4):337-47.
2003: Ricarda Diem; A Tschirne; Mathias Bähr
Decreased amplitudes in multiple sclerosis patients with normal visual acuity: a VEP study.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2003;10(1):67-70.
2002: Argyrios K Stringaris; Jens Geisenhainer; Friederike Bergmann; Christoph Balshüsemann; Unaa Lee; Gregor Zysk; Tim Mitchell; Bernhard U Keller; Ulrich Kuhnt; Joachim Gerber; Annette Spreer; Mathias Bähr; Uwe Michel; Roland Nau
Neurotoxicity of pneumolysin, a major pneumococcal virulence factor, involves calcium influx and depends on activation of p38 mitogen-activated protein kinase.
Neurobiology of disease 2002;11(3):355-68.
2002: Ertugrul Kilic; Dirk M Hermann; Sebastian Kügler; Ulkan Kilic; Harry Holzmüller; Christian Schmeer; Mathias Bähr
Adenovirus-mediated Bcl-X(L) expression using a neuron-specific synapsin-1 promoter protects against disseminated neuronal injury and brain infarction following focal cerebral ischemia in mice.
Neurobiology of disease 2002;11(2):275-84.
2002: Ertugrul Kilic; Gunnar P H Dietz; Dirk M Hermann; Mathias Bähr
Intravenous TAT-Bcl-Xl is protective after middle cerebral artery occlusion in mice.
Annals of neurology 2002;52(5):617-22.
2002: Guido Straten; Christian Schmeer; Alexandra Kretz; Ellen Gerhardt; Sebastian Kügler; Jörg B Schulz; Claude Gravel; Mathias Bähr; Stefan Isenmann
Potential synergistic protection of retinal ganglion cells from axotomy-induced apoptosis by adenoviral administration of glial cell line-derived neurotrophic factor and X-chromosome-linked inhibitor of apoptosis.
Neurobiology of disease 2002;11(1):123-33.
2002: Sonja Jacob; Burkhard Poeggeler; Jochen H Weishaupt; Anna-Leena Sirén; Rüdiger Hardeland; Mathias Bähr; Hannelore Ehrenreich
Melatonin as a candidate compound for neuroprotection in amyotrophic lateral sclerosis (ALS): high tolerability of daily oral melatonin administration in ALS patients.
Journal of pineal research 2002;33(3):186-7.
2002: Gunnar P H Dietz; Ertugrul Kilic; Mathias Bähr
Inhibition of neuronal apoptosis in vitro and in vivo using TAT-mediated protein transduction.
Molecular and cellular neurosciences 2002;21(1):29-37.
2002: Ertugrul Kilic; Dirk M Hermann; Stefan Isenmann; Mathias Bähr
Effects of pinealectomy and melatonin on the retrograde degeneration of retinal ganglion cells in a novel model of intraorbital optic nerve transection in mice.
Journal of pineal research 2002;32(2):106-11.
2002: Marc Gleichmann; G Buchheim; H El-Bizri; Y Yokota; Thomas Klockgether; Sebastian Kügler; Mathias Bähr; Michael Weller; Jörg B Schulz
Identification of inhibitor-of-differentiation 2 (Id2) as a modulator of neuronal apoptosis.
Journal of neurochemistry 2002;80(5):755-62.
2002: Christian Schmeer; Guido Straten; Sebastian Kügler; Claude Gravel; Mathias Bähr; Stefan Isenmann
Dose-dependent rescue of axotomized rat retinal ganglion cells by adenovirus-mediated expression of glial cell-line derived neurotrophic factor in vivo.
The European journal of neuroscience 2002;15(4):637-43.
2002: Wilhelm Küker; Jens Weise; Hilmar Krapf; Friederike Schmidt; Sigrid Friese; Mathias Bähr
MRI characteristics of acute and subacute brainstem and thalamic infarctions: value of T2- and diffusion-weighted sequences.
Journal of neurology 2002;249(1):33-42.
2001: Dirk M Hermann; E Kilic; Sebastian Kügler; Stefan Isenmann; Mathias Bähr
Adenovirus-mediated glial cell line-derived neurotrophic factor (GDNF) expression protects against subsequent cortical cold injury in rats.
Neurobiology of disease 2001;8(6):964-73.
2001: Pawel Kermer; Nikolaj Klöcker; Mathias Bähr
Modulation of metabotropic glutamate receptors fails to prevent the loss of adult rat retinal ganglion cells following axotomy or N-methyl-D-aspartate lesion in vivo.
Neuroscience letters 2001;315(3):117-20.
2001: E Kilic; Mathias Bähr; Dirk M Hermann
Effects of recombinant tissue plasminogen activator after intraluminal thread occlusion in mice: role of hemodynamic alterations.
Stroke; a journal of cerebral circulation 2001;32(11):2641-7.
2001: Nikolaj Klöcker; Martin Zerfowski; Nils-Claudius Gellrich; Mathias Bähr
Morphological and functional analysis of an incomplete CNS fiber tract lesion: graded crush of the rat optic nerve.
Journal of neuroscience methods 2001;110(1-2):147-53.
2001: Jens Weise; Stefan Isenmann; Mathias Bähr
Increased expression and activation of poly(ADP-ribose) polymerase (PARP) contribute to retinal ganglion cell death following rat optic nerve transection.
Cell death and differentiation 2001;8(8):801-7.
2001: Dirk M Hermann; E Kilic; Sebastian Kügler; Stefan Isenmann; Mathias Bähr
Adenovirus-mediated GDNF and CNTF pretreatment protects against striatal injury following transient middle cerebral artery occlusion in mice.
Neurobiology of disease 2001;8(4):655-66.
2001: Ulrike Naumann; Sebastian Kügler; Hartwig Wolburg; Wolfgang Wick; Gesa Rascher; Jörg B Schulz; Emmanuel Conseiller; Mathias Bähr; Michael Weller
Chimeric tumor suppressor 1, a p53-derived chimeric tumor suppressor gene, kills p53 mutant and p53 wild-type glioma cells in synergy with irradiation and CD95 ligand.
Cancer research 2001;61(15):5833-42.
2001: Pawel Kermer; Nikolaj Klöcker; Jochen H Weishaupt; Mathias Bähr
Transection of the optic nerve in rats: studying neuronal death and survival in vivo.
Brain research. Brain research protocols 2001;7(3):255-60.
2001: Ellen Gerhardt; Sebastian Kügler; Marcel Leist; Christoph P Beier; Laura Berliocchi; Christiane Volbracht; Michael Weller; Mathias Bähr; Pierluigi Nicotera; Jörg B Schulz
Cascade of caspase activation in potassium-deprived cerebellar granule neurons: targets for treatment with peptide and protein inhibitors of apoptosis.
Molecular and cellular neurosciences 2001;17(4):717-31.
2001: W Roth; Stefan Isenmann; M Nakamura; Michael Platten; Wolfgang Wick; P Kleihues; Mathias Bähr; H Ohgaki; A Ashkenazi; Michael Weller
Soluble decoy receptor 3 is expressed by malignant gliomas and suppresses CD95 ligand-induced apoptosis and chemotaxis.
Cancer research 2001;61(6):2759-65.
2001: Stefan Isenmann; S Engel; Sebastian Kügler; Claude Gravel; Michael Weller; Mathias Bähr
Intravitreal adenoviral gene transfer evokes an immune response in the retina that is directed against the heterologous lacZ transgene product but does not limit transgene expression.
Brain research 2001;892(2):229-40.
2001: Nikolaj Klöcker; M Jung; C A Stuermer; Mathias Bähr
BDNF increases the number of axotomized rat retinal ganglion cells expressing GAP-43, L1, and TAG-1 mRNA--a supportive role for nitric oxide?
Neurobiology of disease 2001;8(1):103-13.
2001: Jochen H Weishaupt; Mathias Bähr
Degeneration of axotomized retinal ganglion cells as a model for neuronal apoptosis in the central nervous system - molecular death and survival pathways.
Restorative neurology and neuroscience 2001;19(1-2):19-27.
2001: Nikolaj Klöcker; Mathias Bähr
Brain repair--new avenues to an eternal dream?
Trends in neurosciences 2001;24(1):3-4.
2001: Sebastian Kügler; L Meyn; Harry Holzmüller; Ellen Gerhardt; Stefan Isenmann; Jörg B Schulz; Mathias Bähr
Neuron-specific expression of therapeutic proteins: evaluation of different cellular promoters in recombinant adenoviral vectors.
Molecular and cellular neurosciences 2001;17(1):78-96.
2000: Pawel Kermer; R Ankerhold; Nikolaj Klöcker; Stan Krajewski; J C Reed; Mathias Bähr
Caspase-9: involvement in secondary death of axotomized rat retinal ganglion cells in vivo.
Brain research. Molecular brain research 2000;85(1-2):144-50.
2000: Nikolaj Klöcker; Pawel Kermer; Jochen H Weishaupt; M Labes; R Ankerhold; Mathias Bähr
Brain-derived neurotrophic factor-mediated neuroprotection of adult rat retinal ganglion cells in vivo does not exclusively depend on phosphatidyl-inositol-3'-kinase/protein kinase B signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(18):6962-7.
2000: Sebastian Kügler; Guido Straten; F Kreppel; Stefan Isenmann; Peter Liston; Mathias Bähr
The X-linked inhibitor of apoptosis (XIAP) prevents cell death in axotomized CNS neurons in vivo.
Cell death and differentiation 2000;7(9):815-24.
2000: Alessandro Cellerino; Mathias Bähr; S Isenmann
Apoptosis in the developing visual system.
Cell and tissue research 2000;301(1):53-69.
2000: Jens Weise; Stefan Isenmann; Nikolaj Klöcker; Sebastian Kügler; S Hirsch; Claude Gravel; Mathias Bähr
Adenovirus-mediated expression of ciliary neurotrophic factor (CNTF) rescues axotomized rat retinal ganglion cells but does not support axonal regeneration in vivo.
Neurobiology of disease 2000;7(3):212-23.
2000: Pawel Kermer; Nikolaj Klöcker; M Labes; Mathias Bähr
Insulin-like growth factor-I protects axotomized rat retinal ganglion cells from secondary death via PI3-K-dependent Akt phosphorylation and inhibition of caspase-3 In vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(2):2-8.
1999: Pawel Kermer; Nikolaj Klöcker; Mathias Bähr
Neuronal death after brain injury. Models, mechanisms, and therapeutic strategies in vivo.
Cell and tissue research 1999;298(3):383-95.
1999: W Roth; Stefan Isenmann; Ulrike Naumann; Sebastian Kügler; Mathias Bähr; Johannes Dichgans; A Ashkenazi; Michael Weller
Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.
Biochemical and biophysical research communications 1999;265(2):479-83.
1999: Sebastian Kügler; Nikolaj Klöcker; Pawel Kermer; Stefan Isenmann; Mathias Bähr
Transduction of axotomized retinal ganglion cells by adenoviral vector administration at the optic nerve stump: an in vivo model system for the inhibition of neuronal apoptotic cell death.
Gene therapy 1999;6(10):1759-67.
1999: Nikolaj Klöcker; Pawel Kermer; Marc Gleichmann; Michael Weller; Mathias Bähr
Both the neuronal and inducible isoforms contribute to upregulation of retinal nitric oxide synthase activity by brain-derived neurotrophic factor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(19):8517-27.
1999: S Engel; S Isenmann; M Ständer; J Rieger; Mathias Bähr; Michael Weller
Inhibition of experimental rat glioma growth by decorin gene transfer is associated with decreased microglial infiltration.
Journal of neuroimmunology 1999;99(1):13-8.
1999: Stefan Isenmann; S Engel; F Gillardon; Mathias Bähr
Bax antisense oligonucleotides reduce axotomy-induced retinal ganglion cell death in vivo by reduction of Bax protein expression.
Cell death and differentiation 1999;6(7):673-82.
1999: Pawel Kermer; Nikolaj Klöcker; Mathias Bähr
Long-term effect of inhibition of ced 3-like caspases on the survival of axotomized retinal ganglion cells in vivo.
Experimental neurology 1999;158(1):202-5.
1999: Stefan Isenmann; Alessandro Cellerino; Claude Gravel; Mathias Bähr
Excess target-derived brain-derived neurotrophic factor preserves the transient uncrossed retinal projection to the superior colliculus.
Molecular and cellular neurosciences 1999;14(1):52-65.
1999: Pawel Kermer; Nikolaj Klöcker; M Labes; S Thomsen; A Srinivasan; Mathias Bähr
Activation of caspase-3 in axotomized rat retinal ganglion cells in vivo.
FEBS letters 1999;453(3):361-4.
1999: S Hirsch; Mathias Bähr
Immunocytochemical characterization of reactive optic nerve astrocytes and meningeal cells.
Glia 1999;26(1):36-46.
1999: S Hirsch; Mathias Bähr
Growth promoting and inhibitory effects of glial cells in the mammalian nervous system.
Advances in experimental medicine and biology 1999;468():199-205.
1999: M Simons; S Beinroth; Marc Gleichmann; Peter Liston; Robert G Korneluk; Alex E MacKenzie; Mathias Bähr; Thomas Klockgether; G S Robertson; Michael Weller; Jörg B Schulz
Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons.
Journal of neurochemistry 1999;72(1):292-301.
1998: Ullrich Wüllner; Stefan Isenmann; Marc Gleichmann; Thomas Klockgether; Mathias Bähr
Expression of neurotrophins and neurotrophin receptors in the cerebellum of mutant weaver and lurcher mice.
Brain research. Developmental brain research 1998;110(1):1-6.
1998: Stefan Isenmann; Nikolaj Klöcker; Claude Gravel; Mathias Bähr
Short communication: protection of axotomized retinal ganglion cells by adenovirally delivered BDNF in vivo.
The European journal of neuroscience 1998;10(8):2751-6.
1998: Andrea Wizenmann; Mathias Bähr
Growth preferences of adult rat retinal ganglion cell axons in retinotectal cocultures.
Journal of neurobiology 1998;35(4):379-87.
1998: Pawel Kermer; Nikolaj Klöcker; M Labes; Mathias Bähr
Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(12):4656-62.
1998: Nikolaj Klöcker; Alessandro Cellerino; Mathias Bähr
Free radical scavenging and inhibition of nitric oxide synthase potentiates the neurotrophic effects of brain-derived neurotrophic factor on axotomized retinal ganglion cells In vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(3):1038-46.
1998: Stefan Isenmann; G Stoll; M Schroeter; Stan Krajewski; JC Reed; Mathias Bähr
Differential regulation of Bax, Bcl-2, and Bcl-X proteins in focal cortical ischemia in the rat.
Brain pathology (Zurich, Switzerland) 1998;8(1):49-62; discussion 62-3.
1997: Nikolaj Klöcker; F Bräunling; Stefan Isenmann; Mathias Bähr
In vivo neurotrophic effects of GDNF on axotomized retinal ganglion cells.
Neuroreport 1997;8(16):3439-42.
1997: Andrea Wizenmann; Mathias Bähr
Growth characteristics of ganglion cell axons in the developing and regenerating retino-tectal projection of the rat.
Cell and tissue research 1997;290(2):395-403.
1997: Stefan Isenmann; Mathias Bähr
Expression of c-Jun protein in degenerating retinal ganglion cells after optic nerve lesion in the rat.
Experimental neurology 1997;147(1):28-36.
1997: Stefan Isenmann; C Wahl; Stan Krajewski; JC Reed; Mathias Bähr
Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat.
The European journal of neuroscience 1997;9(8):1763-72.
1997: G Struckhoff; C Przyrembel; Mathias Bähr; A Gocht
Fate of developing astrocytes in the optic nerve of the myelin-deficient rat.
The Journal of comparative neurology 1997;378(1):105-16.
1997: Thomas Haarmeier; Karsten Schepelmann; Stephanie Töpfner; Mathias Bähr
[Sympathetic reflex dystrophy in circumscribed stenosis of the abdominal aorta. Case report and discussion of pathophysiologic principles].
Der Nervenarzt 1997;68(2):147-9.
1996: Mathias Bähr; Andrea Wizenmann
Retinal ganglion cell axons recognize specific guidance cues present in the deafferented adult rat superior colliculus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(16):5106-16.
1996: Mathias Bähr; M E Schwab
Antibody that neutralizes myelin-associated inhibitors of axon growth does not interfere with recognition of target-specific guidance information by rat retinal axons.
Journal of neurobiology 1996;30(2):281-92.
1996: Stefan Isenmann; Mathias Bähr; Johannes Dichgans
[Gene therapy of neurologic diseases. Experimental approaches and clinical perspectives].
Der Nervenarzt 1996;67(2):91-108.
1995: Mathias Bähr; C Przyrembel
Myelin from peripheral and central nervous system is a nonpermissive substrate for retinal ganglion cell axons.
Experimental neurology 1995;134(1):87-93.
1995: Mathias Bähr; C Przyrembel; Martin Bastmeyer
Astrocytes from adult rat optic nerves are nonpermissive for regenerating retinal ganglion cell axons.
Experimental neurology 1995;131(2):211-20.
1995: P Wilms; Mathias Bähr
Reactive changes in the adult rat superior colliculus after deafferentation.
Restorative neurology and neuroscience 1995;9(1):21-34.
1994: H Schaden; Claudia A O Stuermer; Mathias Bähr
GAP-43 immunoreactivity and axon regeneration in retinal ganglion cells of the rat.
Journal of neurobiology 1994;25(12):1570-8.
1994: Mathias Bähr; Friedrich Bonhoeffer
Perspectives on axonal regeneration in the mammalian CNS.
Trends in neurosciences 1994;17(11):473-9.
1994: M Hüll; Mathias Bähr
Differential regulation of c-JUN expression in rat retinal ganglion cells after proximal and distal optic nerve transection.
Neuroscience letters 1994;178(1):39-42.
1994: Mathias Bähr; G W Eschweiler; J Dichgans
[Neuronal protection in neurologic diseases?].
Der Nervenarzt 1994;65(6):355-60.
1994: M Hüll; Mathias Bähr
Regulation of immediate-early gene expression in rat retinal ganglion cells after axotomy and during regeneration through a peripheral nerve graft.
Journal of neurobiology 1994;25(1):92-105.
1993: C Przyrembel; Mathias Bähr
Reactive changes of glial cells after optic nerve axotomy in adult rats.
Neuroscience letters 1993;163(2):227-30.
1993: Andrea Wizenmann; E Thies; S Klostermann; Friedrich Bonhoeffer; Mathias Bähr
Appearance of target-specific guidance information for regenerating axons after CNS lesions.
Neuron 1993;11(5):975-83.
1993: A Stevens; Mathias Bähr
Origin of macrophages in central nervous tissue. A study using intraperitoneal transplants contained in Millipore diffusion chambers.
Journal of the neurological sciences 1993;118(2):117-22.
1993: G W Eschweiler; Mathias Bähr
Flunarizine enhances rat retinal ganglion cell survival after axotomy.
Journal of the neurological sciences 1993;116(1):34-40.
1993: Martin Bastmeyer; Mathias Bähr; Claudia A O Stuermer
Fish optic nerve oligodendrocytes support axonal regeneration of fish and mammalian retinal ganglion cells.
Glia 1993;8(1):1-11.
1993: Thomas Herdegen; Martin Bastmeyer; Mathias Bähr; Claudia A O Stuermer; R Bravo; Manfred Zimmermann
Expression of JUN, KROX, and CREB transcription factors in goldfish and rat retinal ganglion cells following optic nerve lesion is related to axonal sprouting.
Journal of neurobiology 1993;24(4):528-43.
1993: Mathias Bähr; G W Eschweiler
Formation of functional synapses by regenerating adult rat retinal ganglion cell axons in midbrain target regions in vitro.
Journal of neurobiology 1993;24(4):456-73.
1992: Claudia A O Stuermer; Martin Bastmeyer; Mathias Bähr; G Strobel; K Paschke
Trying to understand axonal regeneration in the CNS of fish.
Journal of neurobiology 1992;23(5):537-50.
1992: Mathias Bähr; Andrea Wizenmann; Solon Thanos
Effect of bilateral tectum lesions on retinal ganglion cell morphology in rats.
The Journal of comparative neurology 1992;320(3):370-80.
1992: Mathias Bähr; G W Eschweiler; H Wolburg
Precrushed sciatic nerve grafts enhance the survival and axonal regrowth of retinal ganglion cells in adult rats.
Experimental neurology 1992;116(1):13-22.
1991: Mathias Bähr; G W Eschweiler
Regenerating adult rat retinal axons reconnect with target neurons in-vitro.
Neuroreport 1991;2(10):581-4.
1991: Mathias Bähr
Adult rat retinal glia in vitro: effects of in vivo crush-activation on glia proliferation and permissiveness for regenerating retinal ganglion cell axons.
Experimental neurology 1991;111(1):65-73.
1991: Mathias Bähr; J M Hopkins; R P Bunge
In vitro myelination of regenerating adult rat retinal ganglion cell axons by Schwann cells.
Glia 1991;4(5):529-33.
1989: Mathias Bähr; B Schlosshauer
JONES ganglioside expression on retinal glia increases after axotomy.
Journal of neurocytology 1989;18(4):553-63.
1989: Mathias Bähr; J Vanselow; Solon Thanos
Ability of adult rat ganglion cells to regrow axons in vitro can be influenced by fibroblast growth factor and gangliosides.
Neuroscience letters 1989;96(2):197-201.
1988: Mathias Bähr; J Vanselow; Solon Thanos
In vitro regeneration of adult rat ganglion cell axons from retinal explants.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1988;73(2):393-401.