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Sándor Kerpel-Fronius

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TOP 3
Sándor Kerpel-Fronius
[Clinical pharmacology aspects of development and application of biosimilar antibodies].
V Stanulovic; Romána Zelkó; Sándor Kerpel-Fronius
Predictability of serious adverse reaction alerts for monoclonal antibodies.
Sándor Kerpel-Fronius
[Influence of the Nuremberg physicians' trials--beginning a new era in the ethical judging of human experiments].

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All Publications

2012: Sándor Kerpel-Fronius
[Clinical pharmacology aspects of development and application of biosimilar antibodies].
Magyar onkologia 2012;56(2):104-12.
2011: V Stanulovic; Romána Zelkó; Sándor Kerpel-Fronius
Predictability of serious adverse reaction alerts for monoclonal antibodies.
International journal of clinical pharmacology and therapeutics 2011;49(3):185-90.
2008: Sándor Kerpel-Fronius
[Influence of the Nuremberg physicians' trials--beginning a new era in the ethical judging of human experiments].
Orvosi hetilap 2008;149(5):195-201.
2007: Sándor Kerpel-Fronius
[Clinical pharmacologic principles of the development and application of follow-on biological medicinal products].
Orvosi hetilap 2007;148(20):915-21.
2004: Sándor Kerpel-Fronius; Miklós Lóránt
[A new atypical antipsychotic with partial dopamine agonist effect (aripiprazole)].
Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakológiai Egyesület lapja = official journal of the Hungarian Association of Psychopharmacology 2004;6(4):177-84.
2004: Sándor Kerpel-Fronius
[Medical problems associated with the national reference pricing system in Hungary].
Orvosi hetilap 2004;145(17):913-8.
1996: T Schilling; Heinz-Herbert Fiebig; Sándor Kerpel-Fronius; B Winterhalter; P Variol; P Tresca; B Heinrich; Axel R Hanauske
Clinical phase I and pharmacokinetic trial of vinorelbine administered as single intravenous bolus every 21 days in cancer patients.
Investigational new drugs 1996;14(4):371-8.
1996: Sándor Kerpel-Fronius; H Heinisch
[Oral idarubicin in treatment of advanced breast carcinoma].
Zentralblatt für Gynäkologie 1996;118(10):587-9.
1993: J Kralovanszky; N Prajda; Sándor Kerpel-Fronius; T Bagrij; E Kiss; G J Peters
Biochemical consequences of 5-fluorouracil gastrointestinal toxicity in rats; effect of high-dose uridine.
Cancer chemotherapy and pharmacology 1993;32(3):243-8.
1993: Jacek Jassem; F Gyergyay; Sándor Kerpel-Fronius; T Nagykálnai; J Baumöhl; J Verweij; L Vuletic; Z Mechl; M Drozd-Lula; Svetislav Jelic
Combination of daily 4-h infusion of 5-fluorouracil and cisplatin in the treatment of advanced head and neck squamous-cell carcinoma: a South-East European Oncology Group study.
Cancer chemotherapy and pharmacology 1993;31(6):489-94.
1991: Sándor Kerpel-Fronius
[The role of ethical committees in drug trials performed according to "Good Clinical Practice"].
Orvosi hetilap 1991;132(13):703-5.
1990: Irén Számel; Borbála Vincze; I Hindy; Sándor Kerpel-Fronius; S Eckhardt; J Mäenpää; M Grönroos; L Kangas; H Sundquist; A Hajba
Hormonal effects of toremifene in breast cancer patients.
Journal of steroid biochemistry 1990;36(3):243-7.
1990: Dénes Afra; Sándor Kerpel-Fronius; I Szinai; B Kocsis; S Eckhardt
Combined treatment of anaplastic astrocytoma (grade 3-4) with diacetyl-dianhydro-galactitol (DADAG).
Journal of neuro-oncology 1990;8(1):85-91.
1990: I L Sziklai; Dénes Afra; M Ordogh; L Institoris; Sándor Kerpel-Fronius; E Szabo
The distribution of bromine content of dibromodulcitol in the central nervous system of patients with malignant gliomas.
European journal of cancer (Oxford, England : 1990) 1990;26(2):79-82.
1990: S Eckhardt; Z Hernádi; L Thurzó; A Telekes; B Sopkova; Z Mechl; Marek Pawlicki; Sándor Kerpel-Fronius
Phase II clinical evaluation of etoposide (VP-16-213, Vepesid) as a second-line treatment in ovarian cancer. Results of the South-East European Oncology Group (SEEOG) Study.
Oncology 1990;47(4):289-95.
1989: N Prajda; Judit Kralovánszky; F Gal; F Kiss; Sándor Kerpel-Fronius
Evaluation of side effects of platinum complexes (CDDP, CBDCA, CHIP) on rat bone marrow.
In vivo (Athens, Greece) 1989;3(4):267-70.
1989: F Lévai; Z Vargay; G Bujtás; K Tóth; Sándor Kerpel-Fronius; S Eckhardt
[Pharmacokinetics and metabolism of ipriflavone in humans. II].
Acta pharmaceutica Hungarica 1989;59 Suppl 1():38-42.
1988: N Prajda; Judit Kralovánszky; S Somfai-Relle; F Gál; Sándor Kerpel-Fronius
Comparison of tumor growth inhibitory and toxic effects of a new fluorouracil--nitrosourea derivative (B-3839).
In vivo (Athens, Greece) 1988;2(2):151-4.
1988: G Nyerges; Zsófia Mészner; E Gyarmati; Sándor Kerpel-Fronius
Acyclovir prevents dissemination of varicella in immunocompromised children.
The Journal of infectious diseases 1988;157(2):309-13.
1988: Sándor Kerpel-Fronius; V Erdélyi-Tóth; S Somfai-Relle; J Csetényi; P Kovács; G Ujj; B Kanyár
The role of comparative pharmacokinetics in the planning of human dose escalation: the experience with diacetyldianhydrogalactitol.
Cancer chemotherapy and pharmacology 1988;22(2):109-13.
1988: Judit Kralovánszky; N Prajda; Sándor Kerpel-Fronius; F Gál; F Kiss
Comparison of intestinal toxic effects of platinum complexes: cisplatin (CDDP), carboplatin (CBDCA), and iproplatin (CHIP).
Cancer chemotherapy and pharmacology 1988;21(1):40-4.
1988: Sándor Kerpel-Fronius; J Verwey; M Stuurman; B Kanyár; P Lelieveld; HERBERT PINEDO
Pharmacokinetics and toxicity of mitomycin C in rodents, given alone, in combination, or after induction of microsomal drug metabolism.
Cancer chemotherapy and pharmacology 1988;22(2):104-8.
1988: J Verweij; Sándor Kerpel-Fronius; M Stuurman; A J van Triet; L van Hattum; J de Vries; HERBERT PINEDO
Mitomycin C-induced organ toxicity in Wistar rats: a study with special focus on the kidney.
Journal of cancer research and clinical oncology 1988;114(2):137-41.
1988: Irén Számel; I Hindy; Borbála Vincze; Sándor Kerpel-Fronius; S Eckhardt
Influence of antiestrogen drugs on the sex hormone and sex hormone-binding globulin levels in breast cancer patients.
Annals of the New York Academy of Sciences 1988;538():265-79.
1987: G Nyerges; Zsófia Mészner; E Gyarmati; Sándor Kerpel-Fronius
[Acyclovir in the therapy of varicella zoster-caused disease in children undergoing immunosuppressive therapy].
Orvosi hetilap 1987;128(40):2083-8.
1987: Imre Klebovich; J Csetényi; Sándor Kerpel-Fronius; László Vereczkey
Pharmacokinetic studies of [14C]-flumecinol in humans.
Arzneimittel-Forschung 1987;37(3):368-71.
1987: Z Mechl; Sándor Kerpel-Fronius; A Decker; V A Gorbunova; R Gürtler; I Hindy; W Krafft; K Kolarić; M Nekulova; B Sopkova
Comparative evaluation of two administration schedules of cis-dichlorodiammineplatinum (DDP) in ovarian and head and neck cancers: a CMEA chemotherapy group study.
Neoplasma 1987;34(1):37-43.
1987: Sándor Kerpel-Fronius; F Gyergyay; I Hindy; A Decker; I Sawinsky; K Fäller; Z Mechl; M Nekulova; K Kolaric; R Tomek
Phase I-II trial of aclacinomycin A given in a four-consecutive-day schedule to patients with solid tumours. A South-East European Oncology Group (SEEOG) Study.
Oncology 1987;44(3):159-63.
1987: Sándor Kerpel-Fronius; F Gyergyay; I Hindy; A Decker; I Sawinsky; Z Mechl; M Nekulova; K Kolariĉ; R Tomek; J Röthig
Phase II study of aclarubicin in patients with breast cancer previously untreated with adriamycin.
European journal of haematology. Supplementum 1987;47():67-9.
1987: J Verweij; Sándor Kerpel-Fronius; M Stuurman; J de Vries; HERBERT PINEDO
Absence of interaction between furosemide and mitomycin C.
Cancer chemotherapy and pharmacology 1987;19(1):84-6.
1987: M Nekulová; Z Mechl; Sándor Kerpel-Fronius; D Skalková; B Sopková
The excretion of urinary enzymes, proteins and creatinine in patients receiving cisplatinum.
Neoplasma 1987;34(2):183-8.
1987: L Hegedüs; W J van der Vijgh; I Klein; Sándor Kerpel-Fronius; HERBERT PINEDO
Chemical reactivity of cisplatin bound to human plasma proteins.
Cancer chemotherapy and pharmacology 1987;20(3):211-2.
1986: I P Horváth; J Csetényi; Sándor Kerpel-Fronius; L Hegedüs; B Kanyár; S Eckhardt
Pharmacokinetics and metabolism of dianhydrogalactitol DAG in patients: a comparison with the human disposition of dibromodulcitol DBD.
European journal of cancer & clinical oncology 1986;22(2):163-71.
1986: Dénes Afra; B Kocsis; Sándor Kerpel-Fronius; S Eckhardt
Dibromodulcitol-based combined postoperative chemotherapy of malignant astrocytomas and glioblastomas.
Journal of neuro-oncology 1986;4(1):65-70.
1986: Sándor Kerpel-Fronius; V Erdélyi-Tóth; F Gyergyay; I Hindy; Z Mechl; M Nekulová; S Somfai-Relle; P Kovács; G Ujj; B Kanyár
Relation between dose, plasma concentration and toxicity in a phase I trial using high dose intermittent administration of an alkylating agent, diacetyldianhydrogalactitol (DADAG).
Cancer chemotherapy and pharmacology 1986;16(3):264-8.
1986: V Erdélyi-Tóth; Sándor Kerpel-Fronius; B Kanyár; S Eckhardt
Pharmacokinetic study in a phase I trial with an alkylating agent, diacetyldianhydrogalactitol (DADAG).
Cancer chemotherapy and pharmacology 1986;16(3):257-63.
1985: László Vereczkey; M Kozma; Sándor Kerpel-Fronius
Comparative bioavailability studies on different cimetidine preparations.
Acta pharmaceutica Hungarica 1985;55(4):217-20.
1985: N Prajda; Judit Kralovánszky; Sándor Kerpel-Fronius; F Gál; Zoltán Szentirmay
Enzymological and morphological changes in rat intestinal mucosa following treatment with alkylating sugar alcohol derivatives.
Anticancer research 1985;5(4):451-6.
1985: S Eckhardt; Sándor Kerpel-Fronius; I P Horváth; L Institoris
Phase I and II studies of cytostatic hexitol derivatives: the role of alkylating metabolites?
Gan to kagaku ryoho. Cancer & chemotherapy 1985;12(3 Pt 2):783-8.
1984: L Hegedüs; Sándor Kerpel-Fronius; I P Horváth; I Hindy; S Eckhardt
A sensitive assay for the pharmacokinetic investigation of a rapidly hydrolyzing alkylating agent Lycurim (ritrosulfan; R-74; NSC-122 402).
European journal of cancer & clinical oncology 1984;20(7):933-8.
1984: Z Vargay; T Deutsch; I Szatmári; T Szüts; P Várkonyi; Sándor Kerpel-Fronius; S Eckhardt
The fate of drotaverine-acephyllinate in rat and man. II. Human pharmacokinetics of drotaverine-14C-acephyllinate.
European journal of drug metabolism and pharmacokinetics 1984;9(1):17-29.
1983: Sándor Kerpel-Fronius; G Nyerges; Zsófia Mészner; S Eckhardt; E Walker; D Bridgen
[Intravenous acyclovir (ACV, Zovirax) therapy of varicella zoster infections in immunologically endangered patients].
Orvosi hetilap 1983;124(48):2913-8.
1983: J Csetényi; Dénes Afra; Sándor Kerpel-Fronius; I P Horváth; L Institoris; S Eckhardt
The distribution of [3H]-dibromodulcitol in the central nervous system of patients with brain tumour.
European journal of cancer & clinical oncology 1983;19(10):1389-92.
1983: Irén Számel; Borbála Vincze; E Svastits; József Tóth; G Ringwald; Sándor Kerpel-Fronius; S Eckhardt
[Significance of estradiol-progesterone levels in breast tissue in the management of breast cancer].
Orvosi hetilap 1983;124(9):495-9.
1983: Judit Kralovánszky; N Prajda; Sándor Kerpel-Fronius; F Gál; Zoltán Szentirmay
Effect of a single high dose and repeated small doses of dianhydrogalactitol (DAG; NSC-132313) on rat intestinal mucosa.
Cancer chemotherapy and pharmacology 1983;11(3):167-71.
1982: I P Horváth; J Csetényi; I Hindy; Sándor Kerpel-Fronius; I Institoris; I Hegedüs; S Eckhardt
Metabolism and pharmacokinetics of dibromodulcitol (DBD, NSC-104800) in man--II. pharmacokinetics of DBD.
European journal of cancer & clinical oncology 1982;18(11):1211-9.
1982: Imre Klebovich; László Vereczkey; Sándor Kerpel-Fronius; G Ringwald; I Bodrogligeti
Pharmacokinetic studies of flumecinol in man and dog.
European journal of drug metabolism and pharmacokinetics 1982;7(2):99-104.
1982: Sándor Kerpel-Fronius
Hungarian anticancer drugs (antineoplastics).
Therapia Hungarica (English edition) 1982;30(3):110-21.
1981: V Erdélyi-Tóth; J Csetényi; B Kanyár; Sándor Kerpel-Fronius; S Eckhardt
The pharmacokinetics of N-[14C-formyl]-leurosine in humans.
European journal of cancer 1981;17(3):329-35.
1980: Sándor Kerpel-Fronius; J Csetényi; L Hegedüs; I P Horváth; G Ringwald; B Töttössy; S Eckhardt
Chemical reactivity and intracavitary application of alkylating sugar alcohol derivatives.
Oncology 1980;37 Suppl 1():109-14.
1979: I P Horváth; J Csetényi; Sándor Kerpel-Fronius; I Hindy; S Eckhardt
Metabolism and pharmacokinetics of dibromodulcitol (DBD, NSC-104800) in man. I. Metabolites of DBD.
European journal of cancer 1979;15(3):337-44.
1979: M Görlich; E Heise; I Számel; Sándor Kerpel-Fronius
Chemotherapeutic agents and estradiol receptor binding capacity.
Oncology 1979;36(4):149-55.
1978: I Számel; I Hindy; J Csetényi; J Borvendég; I Szente; Sándor Kerpel-Fronius; S Eckhardt
[Clinico-pharmacological study of a Hungarian antiestrogen in patients with advanced breast cancer].
Acta pharmaceutica Hungarica 1978;48 Suppl():51-3.
1978: T Deutsch; T Szüts; Z Vargay; V Bihari; Sándor Kerpel-Fronius; S Eckhardt
[Computer modeling of Probon metabolism and pharmacokinetics].
Acta pharmaceutica Hungarica 1978;48 Suppl():65-7.
1978: V Bihari; T Szüts; Z Vargay; Sándor Kerpel-Fronius; S Eckhardt
[Human pharmacokinetics and metabolism of Probon. II].
Acta pharmaceutica Hungarica 1978;48 Suppl():63-4.
1978: T Szüts; Z Vargay; V Bihari; Sándor Kerpel-Fronius; S Eckhardt
[Human pharmacokinetics and metabolism of Probon. I].
Acta pharmaceutica Hungarica 1978;48 Suppl():60-2.
1978: J Csetényi; L Hegedüs; I Számel; I Bodrogi; Sándor Kerpel-Fronius; S Eckhardt
[Study of Lycurim pharmacokinetics in man].
Acta pharmaceutica Hungarica 1978;48 Suppl():49-51.
1977: S Eckhardt; J Csetényi; I P Horváth; Sándor Kerpel-Fronius; I Számel; L Institóris; F Szlovik; E Pásztor; D Afra
Uptake of labeled dianhydrogalactitol into human gliomas and nervous tissue.
Cancer treatment reports 1977;61(5):841-7.
1977: Sándor Kerpel-Fronius; D P Beck; R W Von Korff
Studies on the metabolism of glutamate and glutamine by mitochondria from rabbit brain: complications due to isotopic exchange reactions.
Journal of neurochemistry 1977;28(4):871-5.
1975: R W Von Korff; Sándor Kerpel-Fronius
The effect of cosubstrates on tricarboxylic acid cycle dynamics during pyruvate oxidation: the formation of alpha-ketoglutarate and utilization of glutamate by mitochondria from rabbit brain.
Journal of neurochemistry 1975;25(6):767-78.
1974: F Hajós; Péter Sótonyi; Sándor Kerpel-Fronius; E Somogyi; G Bujdosó
The ultrastructural demonstration of mitochondrial ATPase activity by the ATP-dependent accumulation of Ca++.
Histochemistry 1974;40(1):89-95.
1973: F Hajós; Sándor Kerpel-Fronius
Comparative electron cytochemical studies of presynaptic and other neuronal mitochondria.
Brain research 1973;62(2):425-9.
1973: Sándor Kerpel-Fronius; I Zs-Nagy
Electron microscopic demonstration of energy production in molluscan neurons.
Acta biologica Academiae Scientiarum Hungaricae 1973;24(1):83-90.
1973: A Korényi-Both; A Szobor; Károly Lapis; I Szathmáry; Sándor Kerpel-Fronius
Fine structural studies in myasthenia gravis. I. Muscle fibre lesions.
European neurology 1973;10(4):215-36.
1972: S H Koslow; Ezio Giacobini; Sándor Kerpel-Fronius; L Olson
Cholinergic transmission in the hypoglossal reinnervated nictitating membrane of the cat: an enzymatic, histochemical and physiological study.
The Journal of pharmacology and experimental therapeutics 1972;180(3):664-71.
1971: F Hajós; Sándor Kerpel-Fronius
Electron microscope histochemical evidence for a partial or total block of the tricarboxylic acid cycle in the mitochondria of presynaptic axon terminals.
The Journal of cell biology 1971;51(1):216-22.
1971: Ezio Giacobini; T Hökfelt; Sándor Kerpel-Fronius; S H Koslow; M Mitchard; B Noré
Micro-scale procedure for the preparation of subcellular fractions from individual autonomic ganglia.
Journal of neurochemistry 1971;18(2):223-31.
1970: Sándor Kerpel-Fronius; F Hajós
Electron microscopic demonostration of energy production and coupled respiration of in situ mitochondria.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1970;18(10):740-5.
1970: Ezio Giacobini; Sándor Kerpel-Fronius
Histochemical and biochemical correlations of monoamine oxidase activity in autonomic and sensory ganglia of the cat.
Acta physiologica Scandinavica 1970;78(4):522-8.
1970: Sándor Kerpel-Fronius; F Hajós
An attempt to evaluate the specificity of the fine structural localization of oxidoreductase activity with a simultaneous coupling method.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1970;18(3):219-21.
1970: F Hajós; T Heim; Sándor Kerpel-Fronius
Electron-microscopic observations in various functional stages of the brown and white adipose tissue in the newborn rabbit.
Biology of the neonate 1970;15(12):94-102.
1970: Ezio Giacobini; K Karjalainen; Sándor Kerpel-Fronius; M Ritzén
Monoamines and monoamine oxidase in denervated sympathetic ganglia of the cat.
Neuropharmacology 1970;9(1):59-66.
1970: I Zs-Nagy; Sándor Kerpel-Fronius
The ultrastructural localization of succinic dehydrogenase activity in the nervous system of Anodonta cygnea L. (Mollusca, pelecypoda).
Acta biologica Academiae Scientiarum Hungaricae 1970;21(1):105-13.
1970: F Hajós; Sándor Kerpel-Fronius
The incubation of unfixed tissues for electron microscopic histochemistry.
Histochemie. Histochemistry. Histochimie 1970;23(2):120-6.
1970: F Hajós; E K Priymak; Sándor Kerpel-Fronius
The electron microscopic demonstration of acetylcholinesterase activity in some cholinergic and non-cholinergic synapses of the rat brain.
Acta histochemica 1970;35(1):114-22.
1970: F Hajós; Sándor Kerpel-Fronius; E Schay
Electron microscopic demonstration of differences between succinic dehydrogenase activities of brain mitochondria in homogenates and mitochondrial fractions.
Acta biochimica et biophysica; Academiae Scientiarum Hungaricae 1970;5(1):19-24.
1969: Ezio Giacobini; Sándor Kerpel-Fronius
Catechol-O-methyltransferase in autonomic and sensory ganglia of the cat.
Acta physiologica Scandinavica 1969;75(4):523-9.
1969: F Hajós; Sándor Kerpel-Fronius
Electron histochemical observation of succinic dehydrogenase activity in various parts of neurons.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1969;8(1):66-78.
1968: Sándor Kerpel-Fronius; F Hajós
The use of ferricyanide for the light and electron microscopic demonstration of succinic dehydrogenase activity.
Histochemie. Histochemistry. Histochimie 1968;14(4):343-51.
1967: Sándor Kerpel-Fronius; F Hajós
A method for the electron microscopic demonstration of cytochrome oxidase in fresh and formalin-prefixed tissues.
Histochemie. Histochemistry. Histochimie 1967;10(3):216-23.
1966: Sándor Kerpel-Fronius; A Kiss; G Than
The effect of pyrogen on body temperature and oxygen consumption in the rat at different environmental temperatures.
Acta physiologica Academiae Scientiarum Hungaricae 1966;29(3):267-71.