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Eli Keshet

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Tamar Licht; Eli Keshet
Delineating multiple functions of VEGF-A in the adult brain.
Oren Gordon; Zhiheng HE; Alon Lazarus; Dalit May; Amit Oppenheim; Dan GILON; Eli Keshet
Vascular endothelial growth factor-induced neovascularization rescues cardiac function but not adverse remodeling at advanced ischemic heart disease.
Alon Lazarus; Eli Keshet
Vascular endothelial growth factor and vascular homeostasis.

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All Publications

2013: Tamar Licht; Eli Keshet
Delineating multiple functions of VEGF-A in the adult brain.
Cellular and molecular life sciences : CMLS 2013;70(10):1727-37.
2012: Oren Gordon; Zhiheng HE; Alon Lazarus; Dalit May; Amit Oppenheim; Dan GILON; Eli Keshet
Vascular endothelial growth factor-induced neovascularization rescues cardiac function but not adverse remodeling at advanced ischemic heart disease.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(7):1642-51.
2011: Alon Lazarus; Eli Keshet
Vascular endothelial growth factor and vascular homeostasis.
Proceedings of the American Thoracic Society 2011;8(6):508-11.
2011: Judith Magenheim; Eyal Mishani; Roni Werman; Oren Ziv; Ayat Hija; Ohad Ilovich; Eli Keshet; Agnes Klochendler; Alon Lazarus; Ondine Cleaver; Yuval Dor
Blood vessels restrain pancreas branching, differentiation and growth.
Development (Cambridge, England) 2011;138(21):4743-52.
2011: Alon Lazarus; Pierre Marie Del-Moral; Ohad Ilovich; Eyal Mishani; David Warburton; Eli Keshet
A perfusion-independent role of blood vessels in determining branching stereotypy of lung airways.
Development (Cambridge, England) 2011;138(11):2359-68.
2011: Shay Sela; Shira Natanson-Yaron; Eyal Zcharia; Israel Vlodavsky; Simcha Yagel; Eli Keshet
Local retention versus systemic release of soluble VEGF receptor-1 are mediated by heparin-binding and regulated by heparanase.
Circulation research 2011;108(9):1063-70.
2011: Tamar Licht; Inbal Goshen; Avi Avital; Tirzah Kreisel; Salman Zubedat; Ronen Eavri; Menahem Segal; Raz Yirmiya; Eli Keshet
Reversible modulations of neuronal plasticity by VEGF.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(12):5081-6.
2011: Dalit May; Rifaat Safadi; Miriam Sklair-Levy; Gideon Zamir; Miklosh Bala; Valentin Djonov; Eli Keshet
A transgenic model for conditional induction and rescue of portal hypertension reveals a role of VEGF-mediated regulation of sinusoidal fenestrations.
PloS one 2011;6(7):e21478.
2010: Edwin C Jesudason; Eli Keshet; David Warburton
Entrained pulmonary clocks: epithelium and vasculature keeping pace.
American journal of physiology. Lung cellular and molecular physiology 2010;299(4):L453-4.
2010: Tamar Licht; Ronen Eavri; Inbal Goshen; Yael Shlomai; Adi Mizrahi; Eli Keshet
VEGF is required for dendritogenesis of newly born olfactory bulb interneurons.
Development (Cambridge, England) 2010;137(2):261-71.
2008: Vicki Plaks; Tal Birnberg; Tamara Berkutzki; Shay Sela; Adi BenYashar; Vyacheslav Kalchenko; Gil Mor; Eli Keshet; Nava Dekel; Michal Neeman; Steffen Jung
Uterine DCs are crucial for decidua formation during embryo implantation in mice.
The Journal of clinical investigation 2008;118(12):3954-65.
2008: Shinji Ueno; Mary Ellen Pease; Delphine M Bonnet Wersinger; Tomohiro Masuda; Stanley A Vinores; Tamar Licht; Donald J Zack; Harry A Quigley; Eli Keshet; Peter A Campochiaro
Prolonged blockade of VEGF family members does not cause identifiable damage to retinal neurons or vessels.
Journal of cellular physiology 2008;217(1):13-22.
2008: Shay Sela; Ahuva Itin; Shira Natanson-Yaron; Caryn Greenfield; Debra Goldman-Wohl; Simcha Yagel; Eli Keshet
A novel human-specific soluble vascular endothelial growth factor receptor 1: cell-type-specific splicing and implications to vascular endothelial growth factor homeostasis and preeclampsia.
Circulation research 2008;102(12):1566-74.
2008: Dalit May; Dan Gilon; Valentin Djonov; Ahuva Itin; Alon Lazarus; Oren Gordon; Christian Rosenberger; Eli Keshet
Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(1):282-7.
2007: Suresh Ramasamy; Arnaud mailleux; Varsha V Gupte; Francisca Mata; Frédéric G Sala; Jacqueline M Veltmaat; Pierre-Marie Del Moral; Stijn P De Langhe; Sara Parsa; Lisa K Kelly; Robert Kelly; Wei Shia; Eli Keshet; Parviz Minoo; David Warburton; Saverio Bellusci
Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development.
Developmental biology 2007;307(2):237-47.
2006: Jacob Hanna; Debra Goldman-Wohl; Yaron Hamani; Inbal Avraham; Caryn Greenfield; Shira Natanson-Yaron; Diana Prus; Leonor Daniel; Tal I Arnon; Irit Manaster; Roi Gazit; Vladimir Yutkin; Daniel Benharroch; Angel Porgador; Eli Keshet; Simcha Yagel; Ofer Mandelboim
Decidual NK cells regulate key developmental processes at the human fetal-maternal interface.
Nature medicine 2006;12(9):1065-74.
2006: Pierre-Marie Del Moral; Frédéric G Sala; Denise Tefft; Wei Shi; Eli Keshet; Saverio Bellusci; David Warburton
VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis.
Developmental biology 2006;290(1):177-88.
2006: Myriam Grunewald; Inbal Avraham; Yuval Dor; Esther Bachar-Lustig; Ahuva Itin; Steffen Jung; Steffen Yung; Stephano Chimenti; Limor Landsman; Rinat Abramovitch; Eli Keshet
VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells.
Cell 2006;124(1):175-89.
2005: Dalit May; Ahuva Itin; Oded Gal; Hagar Kalinski; Elena Feinstein; Eli Keshet
Ero1-L alpha plays a key role in a HIF-1-mediated pathway to improve disulfide bond formation and VEGF secretion under hypoxia: implication for cancer.
Oncogene 2005;24(6):1011-20.
2004: Rinnat M Porat; Myriam Grunewald; Anat Globerman; Ahuva Itin; Gregory Barshtein; Leena Alhonen; Kari Alitalo; Eli Keshet
Specific induction of tie1 promoter by disturbed flow in atherosclerosis-prone vascular niches and flow-obstructing pathologies.
Circulation research 2004;94(3):394-401.
2003: Eli Keshet
Preventing pathological regression of blood vessels.
The Journal of clinical investigation 2003;112(1):27-9.
2003: Yuval Dor; Valentin Djonov; Eli Keshet
Induction of vascular networks in adult organs: implications to proangiogenic therapy.
Annals of the New York Academy of Sciences 2003;995():208-16.
2003: Yuval Dor; Valentin Djonov; Eli Keshet
Making vascular networks in the adult: branching morphogenesis without a roadmap.
Trends in cell biology 2003;13(3):131-6.
2003: Yuval Dor; Scott E Klewer; John A McDonald; Eli Keshet; Todd D Camenisch
VEGF modulates early heart valve formation.
The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 2003;271(1):202-8.
2002: Rotem Karni; Yuval Dor; Eli Keshet; Oded Meyuhas; Alexander Levitzki
Activated pp60c-Src leads to elevated hypoxia-inducible factor (HIF)-1alpha expression under normoxia.
The Journal of biological chemistry 2002;277(45):42919-25.
2002: Veerle Compernolle; Koen Brusselmans; Till Acker; Peter Hoet; Marc Tjwa; Heike Beck; Stephane Plaisance; Yuval Dor; Eli Keshet; Florea Lupu; Benoit Nemery; Mieke Dewerchin; Paul P Van Veldhoven; Karl H Plate; Lieve Moons; Désiré Collen; Peter Carmeliet
Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice.
Nature medicine 2002;8(7):702-10.
2002: Yuval Dor; Valentin Djonov; Rinat Abramovitch; Ahuva Itin; Glenn I Fishman; Peter Carmeliet; Gadi Goelman; Eli Keshet
Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy.
The EMBO journal 2002;21(8):1939-47.
2002: Tzipora Shoshani; Alexander Faerman; Igor Mett; Elena Zelin; Tamar Tenne; Svetlana Gorodin; Yana Moshel; Shlomo Elbaz; Andrei V Budanov; Ayelet Chajut; Hagar Kalinski; Iris Kamer; Ada Rozen; Orna Mor; Eli Keshet; Dena Leshkowitz; Paz Einat; Rami Skaliter; Elena Feinstein
Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.
Molecular and cellular biology 2002;22(7):2283-93.
2002: J Nalinee Upalakalin; Itzhak Hemo; C Dehio; Eli Keshet; Laura E Benjamin
Survival mechanisms of VEGF and PlGF during microvascular remodeling.
Cold Spring Harbor symposia on quantitative biology 2002;67():181-7.
2001: Itay Chowers; Eyal Banin; Y Hemo; Rinnat M Porat; Haya Falk; Eli Keshet; Jacob Pe'er; Amos Panet
Gene transfer by viral vectors into blood vessels in a rat model of retinopathy of prematurity.
The British journal of ophthalmology 2001;85(8):991-5.
2001: Yuval Dor; Rinnat M Porat; Eli Keshet
Vascular endothelial growth factor and vascular adjustments to perturbations in oxygen homeostasis.
American journal of physiology. Cell physiology 2001;280(6):C1367-74.
2001: Yuval Dor; Todd D Camenisch; Ahuva Itin; G I Fishman; John A McDonald; Peter Carmeliet; Eli Keshet
A novel role for VEGF in endocardial cushion formation and its potential contribution to congenital heart defects.
Development (Cambridge, England) 2001;128(9):1531-8.
2001: Eli Keshet
More weapons in the arsenal against ischemic retinopathy.
The Journal of clinical investigation 2001;107(8):945-6.
1999: Y Zhang; Rinnat M Porat; T Alon; Eli Keshet; Jonathan Stone
Tissue oxygen levels control astrocyte movement and differentiation in developing retina.
Brain research. Developmental brain research 1999;118(1-2):135-45.
1999: Eli Keshet; Shmuel A Ben-Sasson
Anticancer drug targets: approaching angiogenesis.
The Journal of clinical investigation 1999;104(11):1497-501.
1999: Stephane Heymans; Aernout Luttun; Dieter Nuyens; Gregor Theilmeier; Esther Creemers; Lieve Moons; G D Dyspersin; Jack P M Cleutjens; M Shipley; A Angellilo; M Levi; O Nübe; A Baker; Eli Keshet; Florea Lupu; Jean-Marc Herbert; Jos F M Smits; S D Shapiro; Myriam Baes; M Borgers; Désiré Collen; Mat J A P Daemen; Peter Carmeliet
Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure.
Nature medicine 1999;5(10):1135-42.
1999: Laura E Benjamin; Dragan Golijanin; Ahuva Itin; Dov Pode; Eli Keshet
Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal.
The Journal of clinical investigation 1999;103(2):159-65.
1998: E Bacharach; Ahuva Itin; Eli Keshet
Apposition-dependent induction of plasminogen activator inhibitor type 1 expression: a mechanism for balancing pericellular proteolysis during angiogenesis.
Blood 1998;92(3):939-45.
1998: Ilan Stein; Ahuva Itin; Paz Einat; Rami Skaliter; Z Grossman; Eli Keshet
Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia.
Molecular and cellular biology 1998;18(6):3112-9.
1998: Laura E Benjamin; Itzhak Hemo; Eli Keshet
A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF.
Development (Cambridge, England) 1998;125(9):1591-8.
1998: Rinat Abramovitch; Michal Neeman; R Reich; Ilan Stein; Eli Keshet; J Abraham; A Solomon; Moshe Marikovsky
Intercellular communication between vascular smooth muscle and endothelial cells mediated by heparin-binding epidermal growth factor-like growth factor and vascular endothelial growth factor.
FEBS letters 1998;425(3):441-7.
1998: Jacob Pe'er; Robert Folberg; Ahuva Itin; H Gnessin; Itzhak Hemo; Eli Keshet
Vascular endothelial growth factor upregulation in human central retinal vein occlusion.
Ophthalmology 1998;105(3):412-6.
1997: Yael S Schiffenbauer; Rinat Abramovitch; Gila Meir; Nava Nevo; M Holzinger; Ahuva Itin; Eli Keshet; Michal Neeman
Loss of ovarian function promotes angiogenesis in human ovarian carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(24):13203-8.
1997: Yuval Dor; Eli Keshet
Ischemia-driven angiogenesis.
Trends in cardiovascular medicine 1997;7(8):289-94.
1997: Jan Provis; J Leech; CM Diaz; Philip L Penfold; Jonathan Stone; Eli Keshet
Development of the human retinal vasculature: cellular relations and VEGF expression.
Experimental eye research 1997;65(4):555-68.
1997: Laura E Benjamin; Eli Keshet
Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(16):8761-6.
1997: Jacob Pe'er; M Neufeld; Mario Baras; H Gnessin; Ahuva Itin; Eli Keshet
Rubeosis iridis in retinoblastoma. Histologic findings and the possible role of vascular endothelial growth factor in its induction.
Ophthalmology 1997;104(8):1251-8.
1996: Jacob Pe'er; Robert Folberg; Ahuva Itin; H Gnessin; Itzhak Hemo; Eli Keshet
Upregulated expression of vascular endothelial growth factor in proliferative diabetic retinopathy.
The British journal of ophthalmology 1996;80(3):241-5.
1996: Jonathan Stone; Tailoi Chan-Ling; Jacob Pe'er; Ahuva Itin; H Gnessin; Eli Keshet
Roles of vascular endothelial growth factor and astrocyte degeneration in the genesis of retinopathy of prematurity.
Investigative ophthalmology & visual science 1996;37(2):290-9.
1995: Ilan Stein; Michal Neeman; D Shweiki; Ahuva Itin; Eli Keshet
Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes.
Molecular and cellular biology 1995;15(10):5363-8.
1995: T Alon; Itzhak Hemo; Ahuva Itin; Jacob Pe'er; Jonathan Stone; Eli Keshet
Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity.
Nature medicine 1995;1(10):1024-8.
1995: M Weil; Ahuva Itin; Eli Keshet
A role for mesenchyme-derived tachykinins in tooth and mammary gland morphogenesis.
Development (Cambridge, England) 1995;121(8):2419-28.
1995: Jonathan Stone; Ahuva Itin; T Alon; Jacob Pe'er; H Gnessin; Tailoi Chan-Ling; Eli Keshet
Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(7 Pt 1):4738-47.
1995: Jacob Pe'er; D Shweiki; Ahuva Itin; Itzhak Hemo; H Gnessin; Eli Keshet
Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularizing ocular diseases.
Laboratory investigation; a journal of technical methods and pathology 1995;72(6):638-45.
1995: D Shweiki; Michal Neeman; Ahuva Itin; Eli Keshet
Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(3):768-72.
1994: Shmuel Banai; D Shweiki; A Pinson; M Chandra; G Lazarovici; Eli Keshet
Upregulation of vascular endothelial growth factor expression induced by myocardial ischaemia: implications for coronary angiogenesis.
Cardiovascular research 1994;28(8):1176-9.
1993: R Schiff; Jonathan Arensburg; Ahuva Itin; Eli Keshet; Joseph Orly
Expression and cellular localization of uterine side-chain cleavage cytochrome P450 messenger ribonucleic acid during early pregnancy in mice.
Endocrinology 1993;133(2):529-37.
1993: D Shweiki; Ahuva Itin; Gera Neufeld; H Gitay-Goren; Eli Keshet
Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis.
The Journal of clinical investigation 1993;91(5):2235-43.
1992: E Bacharach; Ahuva Itin; Eli Keshet
In vivo patterns of expression of urokinase and its inhibitor PAI-1 suggest a concerted role in regulating physiological angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(22):10686-90.
1992: D Shweiki; Ahuva Itin; D Soffer; Eli Keshet
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis.
Nature 1992;359(6398):843-5.
1991: R Schiff; Ahuva Itin; Eli Keshet
Transcriptional activation of mouse retrotransposons in vivo: specific expression in steroidogenic cells in response to trophic hormones.
Genes & development 1991;5(4):521-32.
1991: Eli Keshet; R Schiff; Ahuva Itin
Mouse retrotransposons: a cellular reservoir of long terminal repeat (LTR) elements with diverse transcriptional specificities.
Advances in cancer research 1991;56():215-51.
1990: Tally Naveh-Many; R Marx; Eli Keshet; J W Pike; Justin Silver
Regulation of 1,25-dihydroxyvitamin D3 receptor gene expression by 1,25-dihydroxyvitamin D3 in the parathyroid in vivo.
The Journal of clinical investigation 1990;86(6):1968-75.
1990: Eli Keshet; Ahuva Itin; K Fischman; Uri Nir
The testis-specific transcript (ferT) of the tyrosine kinase FER is expressed during spermatogenesis in a stage-specific manner.
Molecular and cellular biology 1990;10(9):5021-5.
1990: B Motro; Ahuva Itin; L Sachs; Eli Keshet
Pattern of interleukin 6 gene expression in vivo suggests a role for this cytokine in angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(8):3092-6.
1990: H Rosen; Ahuva Itin; R Schiff; Eli Keshet
Local regulation within the female reproductive system and upon embryonic implantation: identification of cells expressing proenkephalin A.
Molecular endocrinology (Baltimore, Md.) 1990;4(1):146-54.
1989: Eli Keshet; Roberto D Polakiewicz; Ahuva Itin; A Ornoy; H Rosen
Proenkephalin A is expressed in mesodermal lineages during organogenesis.
The EMBO journal 1989;8(10):2917-23.
1986: Ahuva Itin; Eli Keshet
A novel retroviruslike family in mouse DNA.
Journal of virology 1986;59(2):301-7.
1986: Ahuva Itin; Eli Keshet
Diverse long terminal repeats are associated with murine retroviruslike (VL30) elements.
Molecular and cellular biology 1986;6(4):1276-82.
1986: G Rotman; Ahuva Itin; Eli Keshet
Promoter and enhancer activities of long terminal repeats associated with cellular retrovirus-like (VL30) elements.
Nucleic acids research 1986;14(2):645-58.
1985: Ahuva Itin; Eli Keshet
Primer binding sites corresponding to several tRNA species are present in DNAs of different members of the same retrovirus-like gene family (VL30).
Journal of virology 1985;54(1):236-9.
1984: G Rotman; Ahuva Itin; Eli Keshet
'Solo' large terminal repeats (LTR) of an endogenous retrovirus-like gene family (VL30) in the mouse genome.
Nucleic acids research 1984;12(5):2273-82.
1983: Ahuva Itin; Eli Keshet
Nucleotide sequence analysis of the long terminal repeat of murine virus-like DNA (VL30) and its adjacent sequences: resemblance to retrovirus proviruses.
Journal of virology 1983;47(3):656-9.
1983: Ahuva Itin; Eli Keshet
Apparent recombinants between virus-liKE (VL30) and murine leukemia virus-related sequences in mouse DNA.
Journal of virology 1983;47(1):178-84.
1983: Ahuva Itin; G Rotman; Eli Keshet
Conservation patterns of mouse "virus-like" (VL30) DNA sequences.
Virology 1983;127(2):374-84.
1982: Eli Keshet; Ahuva Itin
Patterns of genomic distribution and sequence heterogeneity of a murine "retrovirus-like" multigene family.
Journal of virology 1982;43(1):50-8.