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Gary Ketner

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Chi Ying Cheng; Thomas Dobner; Timra Gilson; Gary Ketner; Sabrina Schreiner; Peter Wimmer; Philip E Branton; Paola Blanchette
Role of E1B55K in E4orf6/E1B55K E3 Ligase Complexes Formed by Different Human Adenovirus Serotypes.
Timra Gilson; Amy E Greer; Gary Ketner; Alessandro Vindigni; Leslyn Hanakahi
The α2 helix in the DNA ligase IV BRCT-1 domain is required for targeted degradation of ligase IV during adenovirus infection.
Amy E Greer; Patrick Hearing; Gary Ketner
The adenovirus E4 11 k protein binds and relocalizes the cytoplasmic P-body component Ddx6 to aggresomes.

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All Publications

2013: Chi Ying Cheng; Thomas Dobner; Timra Gilson; Gary Ketner; Sabrina Schreiner; Peter Wimmer; Philip E Branton; Paola Blanchette
Role of E1B55K in E4orf6/E1B55K E3 Ligase Complexes Formed by Different Human Adenovirus Serotypes.
Journal of virology 2013;87(11):6232-45.
2012: Timra Gilson; Amy E Greer; Gary Ketner; Alessandro Vindigni; Leslyn Hanakahi
The α2 helix in the DNA ligase IV BRCT-1 domain is required for targeted degradation of ligase IV during adenovirus infection.
Virology 2012;428(2):128-35.
2011: Amy E Greer; Patrick Hearing; Gary Ketner
The adenovirus E4 11 k protein binds and relocalizes the cytoplasmic P-body component Ddx6 to aggresomes.
Virology 2011;417(1):161-8.
2011: Christopher Palma; Michael Overstreet; Jean-Marc Guedon; Egbert Hoiczyk; Cameron Ward; Kasey A Karen; Fidel Zavala; Gary Ketner
Adenovirus particles that display the Plasmodium falciparum circumsporozoite protein NANP repeat induce sporozoite-neutralizing antibodies in mice.
Vaccine 2011;29(8):1683-9.
2011: Chi Ying Cheng; Timra Gilson; Frédéric Dallaire; Gary Ketner; Philip E Branton; Paola Blanchette
The E4orf6/E1B55K E3 ubiquitin ligase complexes of human adenoviruses exhibit heterogeneity in composition and substrate specificity.
Journal of virology 2011;85(2):765-75.
2009: Balasubramanyam Karanam; Ratish Gambhira; Shiwen Peng; Subhashini Jagu; Dae-Jin Kim; Gary Ketner; Peter L Stern; Robert J Adams; Richard B S Roden
Vaccination with HPV16 L2E6E7 fusion protein in GPI-0100 adjuvant elicits protective humoral and cell-mediated immunity.
Vaccine 2009;27(7):1040-9.
2008: Sumithra Jayaram; Timra Gilson; Elana Ehrlich; XIAOFANG YU; Gary Ketner; Leslyn Hanakahi
E1B 55k-independent dissociation of the DNA ligase IV/XRCC4 complex by E4 34k during adenovirus infection.
Virology 2008;382(2):163-70.
2008: Sumithra Jayaram; Gary Ketner; Noritaka Adachi; Leslyn Hanakahi
Loss of DNA ligase IV prevents recognition of DNA by double-strand break repair proteins XRCC4 and XLF.
Nucleic acids research 2008;36(18):5773-86.
2007: Naseruddin Höti; Ying Li; Chien-Lun Chen; Wasim H Chowdhury; David C Johns; Qinghua Xia; Arup Kabul; Jer-Tsong Hsieh; Michael Berg; Gary Ketner; Shawn E Lupold; Ronald Rodriguez
Androgen receptor attenuation of Ad5 replication: implications for the development of conditionally replication competent adenoviruses.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(8):1495-503.
2007: Amy Baker; Kent J Rohleder; Leslyn Hanakahi; Gary Ketner
Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation.
Journal of virology 2007;81(13):7034-40.
2007: Kun Luo; Elana Ehrlich; Zuoxiang Xiao; Wenyan Zhang; Gary Ketner; XIAOFANG YU
Adenovirus E4orf6 assembles with Cullin5-ElonginB-ElonginC E3 ubiquitin ligase through an HIV/SIV Vif-like BC-box to regulate p53.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(8):1742-50.
2007: Michael Berg; Ratish Gambhira; Mark Siracusa; Egbert Hoiczyk; Richard B S Roden; Gary Ketner
HPV16 L1 capsid protein expressed from viable adenovirus recombinants elicits neutralizing antibody in mice.
Vaccine 2007;25(17):3501-10.
2007: Michael B Smeaton; Paul S Miller; Gary Ketner; Leslyn Hanakahi
Small-scale extracts for the study of nucleotide excision repair and non-homologous end joining.
Nucleic acids research 2007;35(22):e152.
2007: Gary Ketner; Julie Boyer
Isolation, growth, and purification of defective adenovirus deletion mutants.
Methods in molecular medicine 2007;130():19-28.
2007: Julie Boyer; Gary Ketner
Manipulation of early region 4.
Methods in molecular medicine 2007;130():1-17.
2005: Michael Berg; Julie Difatta; Egbert Hoiczyk; Richard Schlegel; Gary Ketner
Viable adenovirus vaccine prototypes: high-level production of a papillomavirus capsid antigen from the major late transcriptional unit.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4590-5.
2004: Paola Blanchette; Chi Ying Cheng; Qin Yan; Gary Ketner; David A Ornelles; Thomas Dobner; Ronald C Conaway; Joan Weliky Conaway; Philip E Branton
Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.
Molecular and cellular biology 2004;24(21):9619-29.
2004: Elham S Mohammadi; Elizabeth A Ketner; David C Johns; Gary Ketner
Expression of the adenovirus E4 34k oncoprotein inhibits repair of double strand breaks in the cellular genome of a 293-based inducible cell line.
Nucleic acids research 2004;32(8):2652-9.
2003: Spencer J Collis; Gary Ketner; Jessica L Hicks; William G Nelson; Angelo M DeMarzo; Theodore L DeWeese
Expression of the DNA-PK binding protein E4-34K fails to confer radiation sensitivity to mammalian cells.
International journal of radiation biology 2003;79(1):53-60.
2002: Sabra L Klein; Aimee L Marson; Alan L Scott; Gary Ketner; Gregory E Glass
Neonatal sex steroids affect responses to Seoul virus infection in male but not female Norway rats.
Brain, behavior, and immunity 2002;16(6):736-46.
2001: Felipe Andrade; Herbert G Bull; Nancy A Thornberry; Gary Ketner; Livia Casciola-Rosen; Antony Rosen
Adenovirus L4-100K assembly protein is a granzyme B substrate that potently inhibits granzyme B-mediated cell death.
Immunity 2001;14(6):751-61.
2000: J L Boyer; Gary Ketner
Genetic analysis of a potential zinc-binding domain of the adenovirus E4 34k protein.
The Journal of biological chemistry 2000;275(20):14969-78.
1999: J Boyer; K Rohleder; Gary Ketner
Adenovirus E4 34k and E4 11k inhibit double strand break repair and are physically associated with the cellular DNA-dependent protein kinase.
Virology 1999;263(2):307-12.
1998: Richard C Marcellus; Josée N Lavoie; Diane B Boivin; Gordon C Shore; Gary Ketner; Philip E Branton
The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis.
Journal of virology 1998;72(9):7144-53.
1997: Susan M Medghalchi; R Padmanabhan; Gary Ketner
Early region 4 modulates adenovirus DNA replication by two genetically separable mechanisms.
Virology 1997;236(1):8-17.
1997: Stephanie Polo; Gary Ketner; R Levis; Barry Falgout
Infectious RNA transcripts from full-length dengue virus type 2 cDNA clones made in yeast.
Journal of virology 1997;71(7):5366-74.
1997: E Querido; Richard C Marcellus; A Lai; R Charbonneau; Jose Teodoro; Gary Ketner; Philip E Branton
Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells.
Journal of virology 1997;71(5):3788-98.
1996: Richard C Marcellus; Jose Teodoro; T Wu; D E Brough; Gary Ketner; Gordon C Shore; Philip E Branton
Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosis.
Journal of virology 1996;70(9):6207-15.
1994: Gary Ketner; Forrest Spencer; Tugendreich Stuart; C Connelly; Philip Hieter
Efficient manipulation of the human adenovirus genome as an infectious yeast artificial chromosome clone.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):6186-90.
1993: E Bridge; S Medghalchi; S Ubol; M Leesong; Gary Ketner
Adenovirus early region 4 and viral DNA synthesis.
Virology 1993;193(2):794-801.
1991: A B Sandler; Gary Ketner
The metabolism of host RNAs in cells infected by an adenovirus E4 mutant.
Virology 1991;181(1):319-26.
1991: C Hemström; Anders Virtanen; E Bridge; Gary Ketner; Ulf Pettersson
Adenovirus E4-dependent activation of the early E2 promoter is insufficient to promote the early-to-late-phase transition.
Journal of virology 1991;65(3):1440-9.
1990: E Bridge; Gary Ketner
Interaction of adenoviral E4 and E1b products in late gene expression.
Virology 1990;174(2):345-53.
1989: Gary Ketner; E Bridge; Anders Virtanen; C Hemström; Ulf Pettersson
Complementation of adenovirus E4 mutants by transient expression of E4 cDNA and deletion plasmids.
Nucleic acids research 1989;17(8):3037-48.
1989: E Bridge; Gary Ketner
Redundant control of adenovirus late gene expression by early region 4.
Journal of virology 1989;63(2):631-8.
1989: A B Sandler; Gary Ketner
Adenovirus early region 4 is essential for normal stability of late nuclear RNAs.
Journal of virology 1989;63(2):624-30.
1988: Barry Falgout; Gary Ketner
Characterization of adenovirus particles made by deletion mutants lacking the fiber gene.
Journal of virology 1988;62(2):622-5.
1987: Barry Falgout; Gary Ketner
Adenovirus early region 4 is required for efficient virus particle assembly.
Journal of virology 1987;61(12):3759-68.
1987: RM Rohan; Gary Ketner
A comprehensive collection of point mutations in the internal promoter of the adenoviral VAI gene.
The Journal of biological chemistry 1987;262(18):8500-7.
1986: David Weinberg; Gary Ketner
Adenoviral early region 4 is required for efficient viral DNA replication and for late gene expression.
Journal of virology 1986;57(3):833-8.
1983: RM Rohan; Gary Ketner
Point mutations in the regulatory region of the human adenoviral VAI gene.
The Journal of biological chemistry 1983;258(19):11576-81.
1983: David Weinberg; Gary Ketner
A cell line that supports the growth of a defective early region 4 deletion mutant of human adenovirus type 2.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(17):5383-6.
1983: B J Carter; C J Marcus-Sekura; C A Laughlin; Gary Ketner
Properties of an adenovirus type 2 mutant, Ad2dl807, having a deletion near the right-hand genome terminus: failure to help AAV replication.
Virology 1983;126(2):505-16.
1981: S S Challberg; Gary Ketner
Deletion mutants of adenovirus 2: isolation and initial characterization of virus carrying mutations near the right end of the viral genome.
Virology 1981;114(1):196-209.
1980: Gary Ketner; Thomas J Kelly
Structure of integrated simian virus 40 DNA in transformed mouse cells.
Journal of molecular biology 1980;144(2):163-82.
1980: A Campbell; R Chang; D Barker; Gary Ketner
Biotin regulatory (bir) mutations of Escherichia coli.
Journal of bacteriology 1980;142(3):1025-8.
1976: Gary Ketner; Thomas J Kelly
Integrated simian virus 40 sequences in transformed cell DNA: analysis using restriction endonucleases.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(4):1102-6.
1975: Gary Ketner; A Campbel
Operator and promoter mutations affecting divergent transcription in the bio gene cluster of Escherichia coli.
Journal of molecular biology 1975;96(1):13-27.
1974: Gary Ketner; A Campbell
A deletion mutation placing the galactokinase gene of Escherichia coli under control of the biotin promoter.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(7):2698-702.