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Saeed Khan

Research Profile

Anatomy

Tumor Cell Line

Chemicals & Drugs

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Publications

TOP 3
Adele L Boskey; Lyudmilla Lukashova; Yan Ma; Lyudmila Spevak; Saeed R Khan
The kidney sodium-phosphate co-transporter alters bone quality in an age and gender specific manner.
Aslam Khan; Saeed R Khan; Anwar H Gilani
Studies on the in vitro and in vivo antiurolithic activity of Holarrhena antidysenterica.
Ziyaur Rahman; Indra K Reddy; Ahmed S Zidan; Saeed R Khan; Mansoor A Khan
Cholorpheniramine tannate complexes: physicochemical, chemometric, and taste masking evaluation.

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All Publications

2013: Adele L Boskey; Lyudmilla Lukashova; Yan Ma; Lyudmila Spevak; Saeed R Khan
The kidney sodium-phosphate co-transporter alters bone quality in an age and gender specific manner.
Bone 2013;53(2):546-53.
2012: Aslam Khan; Saeed R Khan; Anwar H Gilani
Studies on the in vitro and in vivo antiurolithic activity of Holarrhena antidysenterica.
Urological research 2012;40(6):671-81.
2012: Ziyaur Rahman; Indra K Reddy; Ahmed S Zidan; Saeed R Khan; Mansoor A Khan
Cholorpheniramine tannate complexes: physicochemical, chemometric, and taste masking evaluation.
International journal of pharmaceutics 2012;436(1-2):582-92.
2012: Venugopal Chenna; Saeed R Khan; Blake Aftab; Seung-Mo Hong; Nathaniel R Campbell; Dipankar Pramanik; Ming Zhao; Charles Rudin; Collins Karikari; Chaoxin Hu; Michelle A Rudek; Anirban Maitra
A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists.
Molecular cancer therapeutics 2012;11(1):165-73.
2011: Ziyaur Rahman; Ahmed S Zidan; Cyrus Agarabi; Saeed R Khan; Mansoor A Khan
Physico-mechanical and stability evaluation of carbamazepine cocrystal with nicotinamide.
AAPS PharmSciTech 2011;12(2):693-704.
2011: Radharani Marik; Madhan Allu; RAVI ANCHOORI; Vered Stearns; Christopher B Umbricht; Saeed R Khan
Potent genistein derivatives as inhibitors of estrogen receptor alpha-positive breast cancer.
Cancer biology & therapy 2011;11(10):883-92.
2011: Martina Bazzaro; RAVI ANCHOORI; Mohana Krishna Mudiam; Olga Issaenko; Srinivas Kumar; Balasubramanyam Karanam; Zhenhua Lin; Rachel Isaksson Vogel; Riccardo Gavioli; Federica Destro; Valeria Ferretti; Richard B S Roden; Saeed R Khan
α,β-Unsaturated carbonyl system of chalcone-based derivatives is responsible for broad inhibition of proteasomal activity and preferential killing of human papilloma virus (HPV) positive cervical cancer cells.
Journal of medicinal chemistry 2011;54(2):449-56.
2011: Khan Aslam; Saeed R Khan; Samra Bashir; Anwar H Gilani
Antiurolithic activity of Origanum vulgare is mediated through multiple pathways.
BMC complementary and alternative medicine 2011;11():96.
2011: RAVI ANCHOORI; Federica Destro; Alicia Felthauser; Riccardo Gavioli; Yoshie Iizuka; Rachel Isaksson Vogel; Saeed R Khan; Shiwen Peng; Richard B S Roden; Thanasak Sueblinvong; Martina Bazzaro
Stressing the ubiquitin-proteasome system without 20S proteolytic inhibition selectively kills cervical cancer cells.
PloS one 2011;6(8):e23888.
2010: Samra Bashir; Anwarul Hassan Gilani; Anwar A Siddiqui; Shahid Pervez; Saeed R Khan; Noor Jehan Sarfaraz; Abdul Jabbar Shah
Berberis vulgaris root bark extract prevents hyperoxaluria induced urolithiasis in rats.
Phytotherapy research : PTR 2010;24(8):1250-5.
2010: Roppei Yamada; Maya B Kostova; RAVI ANCHOORI; Shili Xu; Nouri Neamati; Saeed R Khan
Biological evaluation of paclitaxel-peptide conjugates as a model for MMP2-targeted drug delivery.
Cancer biology & therapy 2010;9(3):192-203.
2010: RAVI ANCHOORI; Kuzhuvelil B Harikumar; Venkateswara Rao Batchu; Bharat B Aggarwal; Saeed R Khan
Inhibition of IkB kinase and NF-kappaB by a novel synthetic compound SK 2009.
Bioorganic & medicinal chemistry 2010;18(1):229-35.
2009: Shabana Shabbeer; Michelle Sobolewski; RAVI ANCHOORI; Sushant Kachhap; Manuel Hidalgo; Antonio Jimeno; Nancy E Davidson; Michael A Carducci; Saeed R Khan
Fenugreek: a naturally occurring edible spice as an anticancer agent.
Cancer biology & therapy 2009;8(3):272-8.
2008: RAVI ANCHOORI; Madeline Kortenhorst; Manuel Hidalgo; Taradas Sarkar; Gurulingappa Hallur; Ruoli Bai; Paulus van Diest; Ernest Hamel; Saeed R Khan
Novel microtubule-interacting phenoxy pyridine and phenyl sulfanyl pyridine analogues for cancer therapy.
Journal of medicinal chemistry 2008;51(19):5953-7.
2008: Pratap Singh; Gurulingappa Hallur; RAVI ANCHOORI; Oladapo Bakare; Yukio Kageyama; Saeed R Khan; John T Isaacs
Rational design of novel antiandrogens for neutralizing androgen receptor function in hormone refractory prostate cancer.
The Prostate 2008;68(14):1570-81.
2008: Srinivas K Kumar; Indrajit Roy; RAVI ANCHOORI; Sarah Fazli; Anirban Maitra; Philip A Beachy; Saeed R Khan
Targeted inhibition of hedgehog signaling by cyclopamine prodrugs for advanced prostate cancer.
Bioorganic & medicinal chemistry 2008;16(6):2764-8.
2007: Srinivas K Kumar; Simon A Williams; John T Isaacs; Samuel R Denmeade; Saeed R Khan
Modulating paclitaxel bioavailability for targeting prostate cancer.
Bioorganic & medicinal chemistry 2007;15(14):4973-84.
2007: Antonio Jimeno; Gurulingappa Hallur; Audrey Chan; Xiangfeng Zhang; George Cusatis; Fonda Chan; Preeti Shah; Rongbing Chen; Ernest Hamel; Elizabeth Garrett-Mayer; Saeed R Khan; Manuel Hidalgo
Development of two novel benzoylphenylurea sulfur analogues and evidence that the microtubule-associated protein tau is predictive of their activity in pancreatic cancer.
Molecular cancer therapeutics 2007;6(5):1509-16.
2006: Geetha Achanta; Aneta Modzelewska; Li Feng; Saeed R Khan; Peng Huang
A boronic-chalcone derivative exhibits potent anticancer activity through inhibition of the proteasome.
Molecular pharmacology 2006;70(1):426-33.
2006: Aneta Modzelewska; Catherine Pettit; Geetha Achanta; Nancy E Davidson; Peng Huang; Saeed R Khan
Anticancer activities of novel chalcone and bis-chalcone derivatives.
Bioorganic & medicinal chemistry 2006;14(10):3491-5.
2006: Gurulingappa Hallur; Antonio Jimeno; Susan L Dalrymple; Tao Zhu; M Katherine Jung; Manuel Hidalgo; John T Isaacs; Saraswati Sukumar; Ernest Hamel; Saeed R Khan
Benzoylphenylurea sulfur analogues with potent antitumor activity.
Journal of medicinal chemistry 2006;49(7):2357-60.
2005: MICHELLE RUDEK-RENAUT; Ming Zhao; Nicola F Smith; Robert W Robey; Ping He; Gurulingappa Hallur; Saeed R Khan; Manuel Hidalgo; Antonio Jimeno; A Dimitrios Colevas; Wells A Messersmith; Antonio C Wolff; Sharyn D Baker
In vitro and in vivo clinical pharmacology of dimethyl benzoylphenylurea, a novel oral tubulin-interactive agent.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(23):8503-11.
2005: Aneta Modzelewska; Surojit Sur; Srinivas K Kumar; Saeed R Khan
Sesquiterpenes: natural products that decrease cancer growth.
Current medicinal chemistry. Anti-cancer agents 2005;5(5):477-99.
2005: Saeed R Khan; Billie Nowak; William Plunkett; David Farquhar
Bis(pivaloyloxymethyl) thymidine 5'-phosphate is a cell membrane-permeable precursor of thymidine 5'-phosphate in thymidine kinase deficient CCRF CEM cells.
Biochemical pharmacology 2005;69(9):1307-13.
2005: Srinivas K Kumar; Maria Amador; Manuel Hidalgo; Sujata V Bhat; Saeed R Khan
Design, synthesis and biological evaluation of novel riccardiphenol analogs.
Bioorganic & medicinal chemistry 2005;13(8):2873-80.
2005: Saeed R Khan; Srinivas K Kumar; David Farquhar
Bis(carbamoyloxymethyl) esters of 2',3'-dideoxyuridine 5'-monophosphate (ddUMP) as potential ddUMP prodrugs.
Pharmaceutical research 2005;22(3):390-6.
2004: Hallur Gurulingappa; Phillip Buckhalts; Kenneth W Kinzler; Bert Vogelstein; Saeed R Khan
Synthesis and evaluation of aminophosphinic acid derivatives as inhibitors of renal dipeptidase.
Bioorganic & medicinal chemistry letters 2004;14(13):3531-3.
2004: Hallur Gurulingappa; Maria L Amador; Ming Zhao; MICHELLE RUDEK-RENAUT; Manuel Hidalgo; Saeed R Khan
Synthesis and antitumor evaluation of benzoylphenylurea analogs.
Bioorganic & medicinal chemistry letters 2004;14(9):2213-6.
2004: Long H Dang; Chetan Bettegowda; Nishant Agrawal; Ian Cheong; David L Huso; Philip Frost; Frank Loganzo; Lee M Greenberger; Jozsef Barkoczy; George R Pettit; Amos B Smith; Hallur Gurulingappa; Saeed R Khan; Giovanni Parmigiani; Kenneth W Kinzler; Shibin Zhou; Bert Vogelstein
Targeting vascular and avascular compartments of tumors with C. novyi-NT and anti-microtubule agents.
Cancer biology & therapy 2004;3(3):326-37.
2003: Srinivas K Kumar; Erin R Hager; Catherine Pettit; Hallur Gurulingappa; Nancy E Davidson; Saeed R Khan
Design, synthesis, and evaluation of novel boronic-chalcone derivatives as antitumor agents.
Journal of medicinal chemistry 2003;46(14):2813-5.
2003: Samuel R Denmeade; Carsten M Jakobsen; Samuel Janssen; Saeed R Khan; Elizabeth Garrett-Mayer; Hans Lilja; S Brøgger Christensen; John T Isaacs
Prostate-specific antigen-activated thapsigargin prodrug as targeted therapy for prostate cancer.
Journal of the National Cancer Institute 2003;95(13):990-1000.
2002: Annastasiah Mhaka; Samuel R Denmeade; Wei Yao; John T Isaacs; Saeed R Khan
A 5-fluorodeoxyuridine prodrug as targeted therapy for prostate cancer.
Bioorganic & medicinal chemistry letters 2002;12(17):2459-61.
2001: Samuel R Denmeade; Janita Lövgren; Saeed R Khan; Hans Lilja; John T Isaacs
Activation of latent protease function of pro-hK2, but not pro-PSA, involves autoprocessing.
The Prostate 2001;48(2):122-6.
2001: Samuel R Denmeade; Lori J Sokoll; Daniel W Chan; Saeed R Khan; John T Isaacs
Concentration of enzymatically active prostate-specific antigen (PSA) in the extracellular fluid of primary human prostate cancers and human prostate cancer xenograft models.
The Prostate 2001;48(1):1-6.
2001: Saeed R Khan; Annastasiah Mhaka; Roberto Pili; John T Isaacs
Modified synthesis and antiangiogenic activity of linomide.
Bioorganic & medicinal chemistry letters 2001;11(4):451-2.
2000: Saeed R Khan; Samuel R Denmeade
In vivo activity of a PSA-activated doxorubicin prodrug against PSA-producing human prostate cancer xenografts.
The Prostate 2000;45(1):80-3.
1995: David Farquhar; R Chen; Saeed R Khan
5'-[4-(Pivaloyloxy)-1,3,2-dioxaphosphorinan-2-yl]-2'-deoxy-5-fluorouridine: a membrane-permeating prodrug of 5-fluoro-2'-deoxyuridylic acid (FdUMP).
Journal of medicinal chemistry 1995;38(3):488-95.
1994: David Farquhar; Saeed R Khan; D N Srivastva; P P Saunders
Synthesis and antitumor evaluation of bis[(pivaloyloxy)methyl] 2'-deoxy-5-fluorouridine 5'-monophosphate (FdUMP): a strategy to introduce nucleotides into cells.
Journal of medicinal chemistry 1994;37(23):3902-9.
1992: J K Sastry; Pramod N Nehete; Saeed R Khan; B J Nowak; William Plunkett; Ralph B Arlinghaus; D Farquhar
Membrane-permeable dideoxyuridine 5'-monophosphate analogue inhibits human immunodeficiency virus infection.
Molecular pharmacology 1992;41(3):441-5.