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Andriy Khobta

Research Profile

Disorders

DNA Damage

Chemicals & Drugs

Physiology

Living Beings

Mouse

Anatomy

Phenomena

Acetylation

Co-author Network

Publications

TOP 3
Andriy Khobta; Bernd Epe
Repair of oxidatively generated DNA damage in Cockayne syndrome.
Andriy Khobta; Bernd Epe
Interactions between DNA damage, repair, and transcription.
Bork Lühnsdorf; Daniela Warken; Bernd Epe; Nataliya Kitsera; Thomas Lingg; Andriy Khobta
Generation of reporter plasmids containing defined base modifications in the DNA strand of choice.

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All Publications

2013: Andriy Khobta; Bernd Epe
Repair of oxidatively generated DNA damage in Cockayne syndrome.
Mechanisms of ageing and development 2013;134(5-6):253-60.
2012: Andriy Khobta; Bernd Epe
Interactions between DNA damage, repair, and transcription.
Mutation research 2012;736(1-2):5-14.
2012: Bork Lühnsdorf; Daniela Warken; Bernd Epe; Nataliya Kitsera; Thomas Lingg; Andriy Khobta
Generation of reporter plasmids containing defined base modifications in the DNA strand of choice.
Analytical biochemistry 2012;425(1):47-53.
2011: Nataliya Kitsera; Bork Lühnsdorf; Heiko Müller; Dimitrios Stathis; Thomas Carell; Bernd Epe; Andriy Khobta
8-Oxo-7,8-dihydroguanine in DNA does not constitute a barrier to transcription, but is converted into transcription-blocking damage by OGG1.
Nucleic acids research 2011;39(14):5926-34.
2011: Markus Fusser; Gaute J Nesse; Andriy Khobta; Ning Xia; Huige Li; Arne Klungland; Bernd Epe
Spontaneous mutagenesis in Csb(m/m)Ogg1⁻(/)⁻ mice is attenuated by dietary resveratrol.
Carcinogenesis 2011;32(1):80-5.
2010: Andriy Khobta; Thomas Lingg; Ina Schulz; Daniela Warken; Nataliya Kitsera; Bernd Epe
Mouse CSB protein is important for gene expression in the presence of a single-strand break in the non-transcribed DNA strand.
DNA repair 2010;9(9):985-93.
2010: Andriy Khobta; Simon Anderhub; Nataliya Kitsera; Bernd Epe
Gene silencing induced by oxidative DNA base damage: association with local decrease of histone H4 acetylation in the promoter region.
Nucleic acids research 2010;38(13):4285-95.
2009: Andriy Khobta; Nataliya Kitsera; Bodo Speckmann; Bernd Epe
8-Oxoguanine DNA glycosylase (Ogg1) causes a transcriptional inactivation of damaged DNA in the absence of functional Cockayne syndrome B (Csb) protein.
DNA repair 2009;8(3):309-17.
2007: Nataliya Kitsera; Andriy Khobta; Bernd Epe
Destabilized green fluorescent protein detects rapid removal of transcription blocks after genotoxic exposure.
BioTechniques 2007;43(2):222-7.
2007: Ernesto Bockamp; Cerstin Christel; Dorothe Hameyer; Andriy Khobta; Marko Maringer; Marco Reis; Rosario Heck; Nina Cabezas-Wallscheid; Bernd Epe; Barbara Oesch-Bartlomowicz; Bernd Kaina; Steffen Schmitt; Leonid Eshkind
Generation and characterization of tTS-H4: a novel transcriptional repressor that is compatible with the reverse tetracycline-controlled TET-ON system.
The journal of gene medicine 2007;9(4):308-18.
2006: Roberto Tonelli; Roberta Sartini; Raffaele Fronza; F Freccero; Monica Franzoni; D Dongiovanni; Marco Ballarini; S Ferrari; Maria D'Apolito; G Di Cola; Giovanni Capranico; Andriy Khobta; Renato Campanini; Paolo Paolucci; Saverio Minucci; Andrea Pession
G1 cell-cycle arrest and apoptosis by histone deacetylase inhibition in MLL-AF9 acute myeloid leukemia cells is p21 dependent and MLL-AF9 independent.
Leukemia 2006;20(7):1307-10.
2006: Andriy Khobta; Francesca Ferri; Luca Lotito; Alessandra Montecucco; Rossella Rossi; Giovanni Capranico
Early effects of topoisomerase I inhibition on RNA polymerase II along transcribed genes in human cells.
Journal of molecular biology 2006;357(1):127-38.
2004: Andriy Khobta; Carmelo Carlo-Stella; Giovanni Capranico
Specific histone patterns and acetylase/deacetylase activity at the breakpoint-cluster region of the human MLL gene.
Cancer research 2004;64(8):2656-62.
2004: Marco Alessandri; Giovanni L Beretta; Edmondo Ferretti; Annalaura Mancia; Andriy Khobta; Giovanni Capranico
Enhanced CPT sensitivity of yeast cells and selective relaxation of Ga14 motif-containing DNA by novel Gal4-topoisomerase I fusion proteins.
Journal of molecular biology 2004;337(2):295-305.