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Saadi Khochbin

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TOP 3
Hitoshi Shiota; Sophie Rousseaux; Afsaneh Goudarzi; Saadi Khochbin
Shielding Cenp-A removal in post-meiotic male cells.
Hitoshi Shiota; Sophie Rousseaux; Afsaneh Goudarzi; Saadi Khochbin
Transgenerational inheritance of chromatin states.
Karin Sadoul; Anne-Laure Vitte; Jin Wang; Xiaodong Xi; Thierry Buchou; Boubou Diagouraga; Patrick Matthias; Benoît Polack; Thérèse Rossini; Saadi Khochbin
HDAC6 controls the kinetics of platelet activation.

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All Publications

2013: Hitoshi Shiota; Sophie Rousseaux; Afsaneh Goudarzi; Saadi Khochbin
Shielding Cenp-A removal in post-meiotic male cells.
Epigenomics 2013;5(2):122.
2013: Hitoshi Shiota; Sophie Rousseaux; Afsaneh Goudarzi; Saadi Khochbin
Transgenerational inheritance of chromatin states.
Epigenomics 2013;5(2):121-2.
2012: Karin Sadoul; Anne-Laure Vitte; Jin Wang; Xiaodong Xi; Thierry Buchou; Boubou Diagouraga; Patrick Matthias; Benoît Polack; Thérèse Rossini; Saadi Khochbin
HDAC6 controls the kinetics of platelet activation.
Blood 2012;120(20):4215-8.
2012: Jonathan Gaucher; Matthieu Gérard; Philippe Guardiola; Patrick Hery; Hélène Holota; Jean Imbert; Sylvie Jounier; Sarah Bertrand; Fayçal Boussouar; Thierry Buchou; S Curtet; Alexandra Debernardi; Arnaud Depaux; Fabrice Lopez; Emilie Montellier; Karin Pernet; Sophie Rousseaux; Anne-Laure Vitte; Debra J Wolgemuth; Saadi Khochbin
Bromodomain-dependent stage-specific male genome programming by Brdt.
The EMBO journal 2012;31(19):3809-20.
2012: Abir Tadmouri; Satoshi Akiyama; Annie Andrieux; Christophe Arnoult; Eloi Bahembera; Maud Barbado; Sylvain Baulande; Ricardo Dolmetsch; Katell Fablet; Sylvie Gory-Faure; Veerle Janssens; Saadi Khochbin; Shigeki Kiyonaka; Caroline Lambrecht; Florian Lesage; Takafumi Miki; Yasuo Mori; Karin Pernet-Gallay; Michel Ronjat; Matthieu Rousset; Karin Sadoul; Seishiro Sawamura; Michel De Waard
Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy.
The EMBO journal 2012;31(18):3730-44.
2012: Sophie Rousseaux; Saadi Khochbin
Combined proteomic and in silico approaches to decipher post-meiotic male genome reprogramming in mice.
Systems biology in reproductive medicine 2012;58(4):191-6.
2012: Emilie Montellier; Sophie Rousseaux; Saadi Khochbin
[Cross-fire over the nucleosome: molecular basis of post-meiotic male haploid genome compaction].
Médecine sciences : M/S 2012;28(5):485-9.
2012: Emilie Montellier; Sophie Rousseaux; Yingming Zhao; Saadi Khochbin
Histone crotonylation specifically marks the haploid male germ cell gene expression program: post-meiotic male-specific gene expression.
BioEssays : news and reviews in molecular, cellular and developmental biology 2012;34(3):187-93.
2012: Lei Wang; Kendra A Williams; Shengyan Xiang; Wenlong Bai; Gerold Bepler; Huiqin Dong; Saadi Khochbin; Santo V Nicosia; Xiaohong Zhang
Depletion of HDAC6 enhances cisplatin-induced DNA damage and apoptosis in non-small cell lung cancer cells.
PloS one 2012;7(9):e44265.
2011: Minjia Tan; Joanna Wysocka; Jeong Soo Yang; Yang Ye; Zhen Ye; Qin Zhu; Thierry Buchou; Zhongyi Cheng; Fulai Jin; Saadi Khochbin; Sangkyu Lee; Zhike Lu; Hao Luo; Emilie Montellier; Nisha Rajagopal; Bing Ren; Sophie Rousseaux; Yingming Zhao
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification.
Cell 2011;146(6):1016-28.
2011: Saadi Khochbin
In the heart of a dynamic chromatin.
Chemistry & biology 2011;18(4):410-2.
2011: Jin Wang; Anouk Emadali; Aurore Le Bescont; Mary Callanan; Sophie Rousseaux; Saadi Khochbin
Induced malignant genome reprogramming in somatic cells by testis-specific factors.
Biochimica et biophysica acta 2011;1809(4-6):221-5.
2011: Brian E Schwartz; Matthias D Hofer; Madeleine E Lemieux; Daniel E Bauer; Michael J Cameron; Nathan H West; Elin S Agoston; Nicolas Reynoird; Saadi Khochbin; Tan Ince; Amanda Christie; Katherine Anne Janeway; Sara O Vargas; Antonio R Perez-Atayde; Jon C Aster; Stephen E Sallan; Andrew L Kung; James E Bradner; Christopher A French
Differentiation of NUT midline carcinoma by epigenomic reprogramming.
Cancer research 2011;71(7):2686-96.
2011: Valerie Edmond; Elodie Moysan; Saadi Khochbin; Patrick Matthias; Christian Brambilla; Elisabeth Brambilla; Sylvie Gazzeri; Beatrice Eymin
Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin.
The EMBO journal 2011;30(3):510-23.
2011: Sophie Rousseaux; Fayçal Boussouar; Jonathan Gaucher; Nicolas Reynoird; Emilie Montellier; Sandrine Curtet; Anne-Laure Vitte; Saadi Khochbin
Molecular models for post-meiotic male genome reprogramming.
Systems biology in reproductive medicine 2011;57(1-2):50-3.
2011: Karin Sadoul; Jin Wang; Boubou Diagouraga; Saadi Khochbin
The tale of protein lysine acetylation in the cytoplasm.
Journal of biomedicine & biotechnology 2011;2011():970382.
2010: Nicolas Reynoird; Brian E Schwartz; Manuela Delvecchio; Karin Sadoul; DAVID MEYERS; Chandrani Mukherjee; Cécile Caron; Hiroshi Kimura; Sophie Rousseaux; Philip A Cole; Daniel Panne; Christopher A French; Saadi Khochbin
Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains.
The EMBO journal 2010;29(17):2943-52.
2010: Jérôme Govin; Jean Dorsey; Jonathan Gaucher; Sophie Rousseaux; Saadi Khochbin; Shelley L Berger
Systematic screen reveals new functional dynamics of histones H3 and H4 during gametogenesis.
Genes & development 2010;24(16):1772-86.
2010: Jérôme Govin; Jonathan Schug; Thanuja Krishnamoorthy; Jean Dorsey; Saadi Khochbin; Shelley L Berger
Genome-wide mapping of histone H4 serine-1 phosphorylation during sporulation in Saccharomyces cerevisiae.
Nucleic acids research 2010;38(14):4599-606.
2010: Rong Huang; Marc A Holbert; Mary Katherine Tarrant; Sandrine Curtet; David Colquhoun; Beverley M Dancy; Blair C Dancy; You Sang Hwang; Yong Tang; Katrina Meeth; Ronen Marmorstein; Robert N Cole; Saadi Khochbin; Philip A Cole
Site-specific introduction of an acetyl-lysine mimic into peptides and proteins by cysteine alkylation.
Journal of the American Chemical Society 2010;132(29):9986-7.
2010: Alexandra Fournier; Anne McLeer-Florin; Christine Lefebvre; Samuel Duley; Leila Barki; Juliana Ribeyron; Kassambara Alboukadel; Sieme Hamaidia; Aurélie Granjon; Rémy Gressin; Alicia Lajmanovich; Thierry Bonnefoix; Stéphanie Chauvelier; Alexandra Debernardi; Sophie Rousseaux; Florence de Fraipont; Martin Figeac; Jean-Pierre Kerckaert; John De Vos; Yves Usson; Katia Delaval; Alexei Grichine; Claire VOURC'H; Saadi Khochbin; Robert Feil; Dominique Leroux; Mary B Callanan
1q12 chromosome translocations form aberrant heterochromatic foci associated with changes in nuclear architecture and gene expression in B cell lymphoma.
EMBO molecular medicine 2010;2(5):159-71.
2010: Benoit Busser; lucie sancey; Véronique Josserand; Carole Niang; Saadi Khochbin; Marie C Favrot; Jean-Luc Coll; Amandine Hurbin
Amphiregulin promotes resistance to gefitinib in nonsmall cell lung cancer cells by regulating Ku70 acetylation.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(3):536-43.
2010: Sophie Rousseaux; Carlo Petosa; Christoph W Müller; Saadi Khochbin
[A novel key element in post-meiotic male genome reprogramming].
Médecine sciences : M/S 2010;26(2):130-2.
2010: Jonathan Gaucher; Nicolas Reynoird; Emilie Montellier; Fayçal Boussouar; Sophie Rousseaux; Saadi Khochbin
From meiosis to postmeiotic events: the secrets of histone disappearance.
The FEBS journal 2010;277(3):599-604.
2010: Sara A Wickström; Katarzyna C Masoumi; Saadi Khochbin; Reinhard Fässler; Ramin Massoumi
CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin.
The EMBO journal 2010;29(1):131-44.
2009: Sabrina Fritah; Edwige Col; Cyril Boyault; Jérôme Govin; Karin Sadoul; Susanna Chiocca; Elisabeth Christians; Saadi Khochbin; Caroline Jolly; Claire VOURC'H
Heat-shock factor 1 controls genome-wide acetylation in heat-shocked cells.
Molecular biology of the cell 2009;20(23):4976-84.
2009: Sophie Rousseaux; Saadi Khochbin
New hypotheses for large-scale epigenome alterations in somatic cancer cells: a role for male germ-cell-specific regulators.
Epigenomics 2009;1(1):153-61.
2009: Jeanne Morinière; Sophie Rousseaux; Ulrich Steuerwald; Montserrat Soler-López; Sandrine Curtet; Anne-Laure Vitte; Jérôme Govin; Jonathan Gaucher; Karin Sadoul; Darren J Hart; Jeroen Krijgsveld; Saadi Khochbin; Christoph W Müller; Carlo Petosa
Cooperative binding of two acetylation marks on a histone tail by a single bromodomain.
Nature 2009;461(7264):664-8.
2009: Yuliya Zilberman; Christoph Ballestrem; Letizia Carramusa; Ralph Mazitschek; Saadi Khochbin; Alexander D Bershadsky
Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6.
Journal of cell science 2009;122(Pt 19):3531-41.
2009: Angeline EYMERY; Béatrice Horard; Michèle El Atifi-Borel; Geneviève Fourel; François Berger; Anne-Laure Vitte; Arnaud Van den Broeck; Elisabeth Brambilla; Alexandra Fournier; Mary Callanan; Sylvie Gazzeri; Saadi Khochbin; Sophie Rousseaux; Eric Gilson; Claire VOURC'H
A transcriptomic analysis of human centromeric and pericentric sequences in normal and tumor cells.
Nucleic acids research 2009;37(19):6340-54.
2009: Delphine Quénet; Manuel Mark; Jérôme Govin; A van Dorsselear; Valérie Schreiber; Saadi Khochbin; Françoise Dantzer
Parp2 is required for the differentiation of post-meiotic germ cells: identification of a spermatid-specific complex containing Parp1, Parp2, TP2 and HSPA2.
Experimental cell research 2009;315(16):2824-34.
2009: Kazuki Sasaki; Tamaki Ito; Norikazu Nishino; Saadi Khochbin; Minoru Yoshida
Real-time imaging of histone H4 hyperacetylation in living cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(38):16257-62.
2009: Raffaella Catena; Emmanuelle Escoffier; Cécile Caron; Saadi Khochbin; Igor Martianov; Irwin Davidson
HMGB4, a novel member of the HMGB family, is preferentially expressed in the mouse testis and localizes to the basal pole of elongating spermatids.
Biology of reproduction 2009;80(2):358-66.
2009: Saadi Khochbin; Stefan Nonchev
Preface to the "epigenetics and development" special issue.
The International journal of developmental biology 2009;53(2-3):189-90.
2008: Fang Wu; Cécile Caron; Christine De Robertis; Saadi Khochbin; Sophie Rousseaux
Testis-specific histone variants H2AL1/2 rapidly disappear from paternal heterochromatin after fertilization.
The Journal of reproduction and development 2008;54(6):413-7.
2008: Fayçal Boussouar; Sophie Rousseaux; Saadi Khochbin
A new insight into male genome reprogramming by histone variants and histone code.
Cell cycle (Georgetown, Tex.) 2008;7(22):3499-502.
2008: Arnaud Van Den Broeck; Elisabeth Brambilla; denis moro-sibilot; Sylvie Lantuejoul; Christian Brambilla; Beatrice Eymin; Saadi Khochbin; Sylvie Gazzeri
Loss of histone H4K20 trimethylation occurs in preneoplasia and influences prognosis of non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(22):7237-45.
2008: Kazuo Kamemura; Akihiro Ito; Tadahiro Shimazu; Akihisa Matsuyama; Satoko Maeda; Tso-Pang Yao; Sueharu Horinouchi; Saadi Khochbin; Minoru Yoshida
Effects of downregulated HDAC6 expression on the proliferation of lung cancer cells.
Biochemical and biophysical research communications 2008;374(1):84-9.
2008: Sophie Rousseaux; Nicolas Reynoird; Jonathan Gaucher; Saadi Khochbin
[Intrusion of male epigenome regulators in somatic cancer cells].
Médecine sciences : M/S 2008;24(8-9):735-41.
2008: Yu Zhang; Sohee Kwon; Teppei Yamaguchi; fabien cubizolles; Sophie Rousseaux; Michaela Kneissel; Chun Cao; Na Li; Hwei-Ling Cheng; Katrin Chua; David Lombard; Adam Mizeracki; Gabriele Matthias; Frederick W Alt; Saadi Khochbin; Patrick Matthias
Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally.
Molecular and cellular biology 2008;28(5):1688-701.
2008: Karin Sadoul; Cyril Boyault; Michel Pabion; Saadi Khochbin
Regulation of protein turnover by acetyltransferases and deacetylases.
Biochimie 2008;90(2):306-12.
2008: Cyril Boyault; Saadi Khochbin
[HDAC6 orchestrates cell defense responses against cytotoxic protein aggregates].
Médecine sciences : M/S 2008;24(1):15-7.
2008: Patrick Matthias; Minoru Yoshida; Saadi Khochbin
HDAC6 a new cellular stress surveillance factor.
Cell cycle (Georgetown, Tex.) 2008;7(1):7-10.
2008: Pasqualino Loi; Nathalie Beaujean; Saadi Khochbin; Josef Fulka; Grazyna Ptak
Asymmetric nuclear reprogramming in somatic cell nuclear transfer?
BioEssays : news and reviews in molecular, cellular and developmental biology 2008;30(1):66-74.
2007: Luigi Gomez-Paloma; Ines Bruno; Elena Cini; Saadi Khochbin; Manuela Rodriquez; Maurizio Taddei; Stefania Terracciano; Karin Sadoul
Design and synthesis of cyclopeptide analogues of the potent histone deacetylase inhibitor FR235222.
ChemMedChem 2007;2(10):1511-9.
2007: Cyril Boyault; Yu Zhang; Sabrina Fritah; Cécile Caron; Benoit Gilquin; So Hee Kwon; Carmen Garrido; Tso-Pang Yao; Claire VOURC'H; Patrick Matthias; Saadi Khochbin
HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates.
Genes & development 2007;21(17):2172-81.
2007: Cyril Boyault; K Sadoul; M Pabion; Saadi Khochbin
HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination.
Oncogene 2007;26(37):5468-76.
2007: Katia Delaval; Jerome Govin; Frédérique Cerqueira; Sophie Rousseaux; Saadi Khochbin; Robert Feil
Differential histone modifications mark mouse imprinting control regions during spermatogenesis.
The EMBO journal 2007;26(3):720-9.
2007: Jerome Govin; Emmanuelle Escoffier; Sophie Rousseaux; Lauriane Kuhn; Myriam Ferro; Julien Thévenon; Raffaella Catena; Irwin Davidson; Jérôme Garin; Saadi Khochbin; Cécile Caron
Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis.
The Journal of cell biology 2007;176(3):283-94.
2006: Jerome Govin; Cécile Caron; Emmanuelle Escoffier; Myriam Ferro; Lauriane Kuhn; Sophie Rousseaux; Edward Eddy; Jérôme Garin; Saadi Khochbin
Post-meiotic shifts in HSPA2/HSP70.2 chaperone activity during mouse spermatogenesis.
The Journal of biological chemistry 2006;281(49):37888-92.
2006: Thanuja Krishnamoorthy; Xin Chen; Jerome Govin; Wang L Cheung; Jean A Dorsey; Karen Schindler; Edward Winter; C David Allis; Vincent Guacci; Saadi Khochbin; Margaret T Fuller; Shelley L Berger
Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis.
Genes & development 2006;20(18):2580-92.
2006: Sophie Rousseaux; Anne-Karen Faure; J Thévenon; Emmanuelle Escoffier; Cecile Neubert; Jerome Govin; Sylviane Hennebicq; Bernard Sèle; Cécile Caron; Saadi Khochbin
[Epigenetics of the sperm cell].
Gynécologie, obstétrique & fertilité 2006;34(9):831-5.
2006: Cyril Boyault; Benoit Gilquin; Yu Zhang; Vladimir Rybin; Elspeth Garman; Wolfram Meyer-Klaucke; Patrick Matthias; Christoph W Müller; Saadi Khochbin
HDAC6-p97/VCP controlled polyubiquitin chain turnover.
The EMBO journal 2006;25(14):3357-66.
2006: Camille Leduc; Paule Claverie; Béatrice Eymin; Edwige Col; Saadi Khochbin; Elisabeth Brambilla; Sylvie Gazzeri
p14ARF promotes RB accumulation through inhibition of its Tip60-dependent acetylation.
Oncogene 2006;25(30):4147-54.
2006: Béatrice Eymin; Paule Claverie; Caroline Salon; Camille Leduc; Edwige Col; Elisabeth Brambilla; Saadi Khochbin; Sylvie Gazzeri
p14ARF activates a Tip60-dependent and p53-independent ATM/ATR/CHK pathway in response to genotoxic stress.
Molecular and cellular biology 2006;26(11):4339-50.
2006: Arnaud Parcellier; Mathilde Brunet; Elise Schmitt; Edwige Col; Celine Didelot; Arlette Hammann; Keiko Nakayama; Keiichi I Nakayama; Saadi Khochbin; Eric Solary; Carmen Garrido
HSP27 favors ubiquitination and proteasomal degradation of p27Kip1 and helps S-phase re-entry in stressed cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(8):1179-81.
2006: Alexander D Bershadsky; Christoph Ballestrem; Letizia Carramusa; Yuliya Zilberman; Benoit Gilquin; Saadi Khochbin; Antonina Y Alexandrova; Alexander B Verkhovsky; Tom Shemesh; Michael M Kozlov
Assembly and mechanosensory function of focal adhesions: experiments and models.
European journal of cell biology 2006;85(3-4):165-73.
2006: Yu Zhang; Benoit Gilquin; Saadi Khochbin; Patrick Matthias
Two catalytic domains are required for protein deacetylation.
The Journal of biological chemistry 2006;281(5):2401-4.
2006: Jerome Govin; Cecile Neubert; Cécile Caron; Christophe Pivot-Pajot; Sophie Rousseaux; Saadi Khochbin
Histone acetylation-mediated chromatin compaction during mouse spermatogenesis.
Ernst Schering Research Foundation workshop 2006;(57):155-72.
2006: Yves Charron; Rime MADANI; Serge Nef; Chantal Combepine; Jerome Govin; Saadi Khochbin; Jean-Dominique Vassalli
Expression of serpinb6 serpins in germ and somatic cells of mouse gonads.
Molecular reproduction and development 2006;73(1):9-19.
2005: Guillaume Octobre; Claudie Lemercier; Saadi Khochbin; Michel Robert-Nicoud; Catherine Souchier
Monitoring the interaction between DNA and a transcription factor (MEF2A) using fluorescence correlation spectroscopy.
Comptes rendus biologies 2005;328(12):1033-40.
2005: Srinivas Chakravarthy; Sampath Kumar Y Gundimella; Cecile Caron; Pierre-Yves Perche; John R Pehrson; Saadi Khochbin; Karolin Luger
Structural characterization of the histone variant macroH2A.
Molecular and cellular biology 2005;25(17):7616-24.
2005: Leila Barki-Celli; Christine Lefebvre; Patricia Le Baccon; Gwenael Nadeau; Thierry Bonnefoix; Yves Usson; Claire VOURC'H; Saadi Khochbin; Dominique Leroux; Mary Callanan
Differences in nuclear positioning of 1q12 pericentric heterochromatin in normal and tumor B lymphocytes with 1q rearrangements.
Genes, chromosomes & cancer 2005;43(4):339-49.
2005: Edwige Col; Cécile Caron; Christine Chable-Bessia; Gaëlle Legube; Sylvie Gazzeri; Yasuhiko Komatsu; Minoru Yoshida; Monsef Benkirane; Didier Trouche; Saadi Khochbin
HIV-1 Tat targets Tip60 to impair the apoptotic cell response to genotoxic stresses.
The EMBO journal 2005;24(14):2634-45.
2005: Olivier Destaing; Frédéric Saltel; Benoit Gilquin; Anne Chabadel; Saadi Khochbin; Stéphane Ory; Pierre Jurdic
A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts.
Journal of cell science 2005;118(Pt 13):2901-11.
2005: Jerome Govin; Cécile Caron; Sophie Rousseaux; Saadi Khochbin
Testis-specific histone H3 expression in somatic cells.
Trends in biochemical sciences 2005;30(7):357-9.
2005: Cécile Caron; Cyril Boyault; Saadi Khochbin
Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability.
BioEssays : news and reviews in molecular, cellular and developmental biology 2005;27(4):408-15.
2005: Alexandre Méjat; Francis Ramond; Rhonda Bassel-Duby; Saadi Khochbin; Eric N Olson; Laurent Schaeffer
Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression.
Nature neuroscience 2005;8(3):313-21.
2005: Sophie Rousseaux; Cécile Caron; Jerome Govin; Cecile Neubert; Anne-Karen Faure; Saadi Khochbin
Establishment of male-specific epigenetic information.
Gene 2005;345(2):139-53.
2005: Cécile Caron; Jerome Govin; Sophie Rousseaux; Saadi Khochbin
How to pack the genome for a safe trip.
Progress in molecular and subcellular biology 2005;38():65-89.
2004: Nicholas Bertos; Benoit Gilquin; Gordon K T Chan; Tim J Yen; Saadi Khochbin; Xiang-Jiao Yang
Role of the tetradecapeptide repeat domain of human histone deacetylase 6 in cytoplasmic retention.
The Journal of biological chemistry 2004;279(46):48246-54.
2004: Sophie Rousseaux; Anne-Karen Faure; Cécile Caron; Cecile Neubert; Jerome Govin; Sylviane Hennebicq; Bernard Sèle; Saadi Khochbin
[Organizing the sperm nucleus].
Gynécologie, obstétrique & fertilité 2004;32(9):785-91.
2004: Jerome Govin; Cécile Caron; Cecile Neubert; Sophie Rousseaux; Saadi Khochbin
The role of histones in chromatin remodelling during mammalian spermiogenesis.
European journal of biochemistry / FEBS 2004;271(17):3459-69.
2004: Patrick Lomonte; Joëlle Thomas; Pascale Texier; Cécile Caron; Saadi Khochbin; Alberto L Epstein
Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1.
Journal of virology 2004;78(13):6744-57.
2004: Caroline Jolly; Alexandra Metz; Jerome Govin; Marc Vigneron; Bryan M Turner; Saadi Khochbin; Claire VOURC'H
Stress-induced transcription of satellite III repeats.
The Journal of cell biology 2004;164(1):25-33.
2004: Audrey Castet; Abdelhay Boulahtouf; Gwennaëlle Versini; Sandrine Bonnet; Patrick Augereau; Françoise Vignon; Saadi Khochbin; Stéphan Jalaguier; Vincent Cavaillès
Multiple domains of the Receptor-Interacting Protein 140 contribute to transcription inhibition.
Nucleic acids research 2004;32(6):1957-66.
2003: André Verdel; Daphné Seigneurin-Berny; Anne-Karen Faure; Mina Eddahbi; Saadi Khochbin; Stefan Nonchev
HDAC6-induced premature chromatin compaction in mouse oocytes and fertilised eggs.
Zygote (Cambridge, England) 2003;11(4):323-8.
2003: Pierre-Yves Perche; Michel Robert-Nicoud; Saadi Khochbin; Claire VOURC'H
[Nucleosome differentiation: role of histone H2A variants].
Médecine sciences : M/S 2003;19(11):1137-45.
2003: Cécile Caron; Christophe Pivot-Pajot; Leo van Grunsven; Edwige Col; Cecile Neubert; Sophie Rousseaux; Saadi Khochbin
Cdyl: a new transcriptional co-repressor.
EMBO reports 2003;4(9):877-82.
2003: Didier Trouche; Saadi Khochbin; Stefan Dimitrov
Chromatin and epigenetics: dynamic organization meets regulated function.
Molecular cell 2003;12(2):281-6.
2003: Arnaud Parcellier; Elise Schmitt; Sandeep Gurbuxani; Daphné Seigneurin-Berny; Alena Pance; Aurélie Chantôme; Stéphanie Plenchette; Saadi Khochbin; Eric Solary; Carmen Garrido
HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation.
Molecular and cellular biology 2003;23(16):5790-802.
2003: Christophe Pivot-Pajot; Cécile Caron; Jerome Govin; Alexandre Vion; Sophie Rousseaux; Saadi Khochbin
Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein.
Molecular and cellular biology 2003;23(15):5354-65.
2003: Germaine Fu; Parinaz Ghadam; Allen Sirotkin; Saadi Khochbin; Arthur I Skoultchi; Hugh J Clarke
Mouse oocytes and early embryos express multiple histone H1 subtypes.
Biology of reproduction 2003;68(5):1569-76.
2003: Dimitar Angelov; Annie Molla; Pierre-Yves Perche; Fabienne Hans; Jacques Côté; Saadi Khochbin; Philippe Bouvet; Stefan Dimitrov
The histone variant macroH2A interferes with transcription factor binding and SWI/SNF nucleosome remodeling.
Molecular cell 2003;11(4):1033-41.
2003: Yu Zhang; Na Li; Cécile Caron; Gabriele Matthias; daniel Hess; Saadi Khochbin; Patrick Matthias
HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo.
The EMBO journal 2003;22(5):1168-79.
2003: Claudie Lemercier; Gaëlle Legube; Cécile Caron; Mathilde Louwagie; Jérôme Garin; Didier Trouche; Saadi Khochbin
Tip60 acetyltransferase activity is controlled by phosphorylation.
The Journal of biological chemistry 2003;278(7):4713-8.
2003: Cécile Caron; Edwige Col; Saadi Khochbin
The viral control of cellular acetylation signaling.
BioEssays : news and reviews in molecular, cellular and developmental biology 2003;25(1):58-65.
2002: Akihisa Matsuyama; Tadahiro Shimazu; Yuko Sumida; Akiko Saito; Yasuhiro Yoshimatsu; Daphné Seigneurin-Berny; Hiroyuki Osada; Yasuhiko Komatsu; Norikazu Nishino; Saadi Khochbin; Sueharu Horinouchi; Minoru Yoshida
In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation.
The EMBO journal 2002;21(24):6820-31.
2002: Edwige Col; Benoit Gilquin; Cécile Caron; Saadi Khochbin
Tat-controlled protein acetylation.
The Journal of biological chemistry 2002;277(40):37955-60.
2002: Claudie Lemercier; Marie-Paule Brocard; Francine Puvion-Dutilleul; Hung-Ying Kao; Olivier Albagli; Saadi Khochbin
Class II histone deacetylases are directly recruited by BCL6 transcriptional repressor.
The Journal of biological chemistry 2002;277(24):22045-52.
2002: Gaëlle Legube; Laëtitia K Linares; Claudie Lemercier; Martin Scheffner; Saadi Khochbin; Didier Trouche
Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation.
The EMBO journal 2002;21(7):1704-12.
2001: Hung-Ying Kao; André Verdel; C C Tsai; C Simon; H Juguilon; Saadi Khochbin
Mechanism for nucleocytoplasmic shuttling of histone deacetylase 7.
The Journal of biological chemistry 2001;276(50):47496-507.
2001: Daphné Seigneurin-Berny; André Verdel; S Curtet; Claudie Lemercier; Jérôme Garin; Sophie Rousseaux; Saadi Khochbin
Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways.
Molecular and cellular biology 2001;21(23):8035-44.
2001: Edwige Col; Cécile Caron; Daphné Seigneurin-Berny; J Gracia; alain favier; Saadi Khochbin
The histone acetyltransferase, hGCN5, interacts with and acetylates the HIV transactivator, Tat.
The Journal of biological chemistry 2001;276(30):28179-84.
2001: Saadi Khochbin
Histone H1 diversity: bridging regulatory signals to linker histone function.
Gene 2001;271(1):1-12.
2001: Saadi Khochbin; Hung-Ying Kao
Histone deacetylase complexes: functional entities or molecular reservoirs.
FEBS letters 2001;494(3):141-4.
2001: Saadi Khochbin; André Verdel; Claudie Lemercier; Daphné Seigneurin-Berny
Functional significance of histone deacetylase diversity.
Current opinion in genetics & development 2001;11(2):162-6.
2000: Mira Hazzouri; Christophe Pivot-Pajot; A K Faure; Yves Usson; Roberte Pelletier; Bernard Sèle; Saadi Khochbin; Sophie Rousseaux
Regulated hyperacetylation of core histones during mouse spermatogenesis: involvement of histone deacetylases.
European journal of cell biology 2000;79(12):950-60.
2000: Pierre-Yves Perche; Claire VOURC'H; L Konecny; Catherine Souchier; Michel Robert-Nicoud; Stefan Dimitrov; Saadi Khochbin
Higher concentrations of histone macroH2A in the Barr body are correlated with higher nucleosome density.
Current biology : CB 2000;10(23):1531-4.
2000: Dimitar Angelov; Monique Charra; Seve Michel; J Côté; Saadi Khochbin; Stefan Dimitrov
Differential remodeling of the HIV-1 nucleosome upon transcription activators and SWI/SNF complex binding.
Journal of molecular biology 2000;302(2):315-26.
2000: Claudie Lemercier; K Duncliffe; I Boibessot; H Zhang; André Verdel; Dimitar Angelov; Saadi Khochbin
Involvement of retinoblastoma protein and HBP1 in histone H1(0) gene expression.
Molecular and cellular biology 2000;20(18):6627-37.
2000: André Verdel; S Curtet; Marie-Paule Brocard; Sophie Rousseaux; Claudie Lemercier; M Yoshida; Saadi Khochbin
Active maintenance of mHDA2/mHDAC6 histone-deacetylase in the cytoplasm.
Current biology : CB 2000;10(12):747-9.
2000: Claudie Lemercier; André Verdel; B Galloo; S Curtet; Marie-Paule Brocard; Saadi Khochbin
mHDA1/HDAC5 histone deacetylase interacts with and represses MEF2A transcriptional activity.
The Journal of biological chemistry 2000;275(20):15594-9.
2000: M Callanan; N Kudo; S Gout; Marie-Paule Brocard; M Yoshida; S Dimitrov; Saadi Khochbin
Developmentally regulated activity of CRM1/XPO1 during early Xenopus embryogenesis.
Journal of cell science 2000;113 ( Pt 3)():451-9.
1999: Dimitar Angelov; E Novakov; Saadi Khochbin; Stefan Dimitrov
Ultraviolet laser footprinting of histone H1(0)-four-way junction DNA complexes.
Biochemistry 1999;38(35):11333-9.
1999: M Creaven; Fabienne Hans; V Mutskov; Edwige Col; Cécile Caron; Stefan Dimitrov; Saadi Khochbin
Control of the histone-acetyltransferase activity of Tip60 by the HIV-1 transactivator protein, Tat.
Biochemistry 1999;38(27):8826-30.
1999: André Verdel; Saadi Khochbin
Identification of a new family of higher eukaryotic histone deacetylases. Coordinate expression of differentiation-dependent chromatin modifiers.
The Journal of biological chemistry 1999;274(4):2440-5.
1999: D Angelov; Saadi Khochbin; S Dimitrov
UV laser footprinting and protein-DNA crosslinking. Application to chromatin.
Methods in molecular biology (Clifton, N.J.) 1999;119():481-95.
1999: D Grunwald; C Gorka; S Curtet; Saadi Khochbin
In situ analysis of chromatin proteins during development and cell differentiation using flow cytometry.
Methods in molecular biology (Clifton, N.J.) 1999;119():443-54.
1998: M Cesari; L Héliot; C Meplan; Michel Pabion; Saadi Khochbin
S-phase-dependent action of cycloheximide in relieving chromatin-mediated general transcriptional repression.
The Biochemical journal 1998;336 ( Pt 3)():619-24.
1998: C Gorka; Marie-Paule Brocard; S Curtet; Saadi Khochbin
Differential recognition of histone H10 by monoclonal antibodies during cell differentiation and the arrest of cell proliferation.
The Journal of biological chemistry 1998;273(2):1208-15.
1997: Saadi Khochbin; A P Wolffe
The origin and utility of histone deacetylases.
FEBS letters 1997;419(2-3):157-60.
1997: Marie-Paule Brocard; S Triebe; M Peretti; D Doenecke; Saadi Khochbin
Characterization of the two H1(zero)-encoding genes from Xenopus laevis.
Gene 1997;189(1):127-34.
1997: Alan P Wolffe; Saadi Khochbin; Stefan Dimitrov
What do linker histones do in chromatin?
BioEssays : news and reviews in molecular, cellular and developmental biology 1997;19(3):249-55.
1997: M Peretti; Saadi Khochbin
The evolution of the differentiation-specific histone H1 gene basal promoter.
Journal of molecular evolution 1997;44(2):128-34.
1995: D Seigneurin; D Grunwald; J J Lawrence; Saadi Khochbin
Developmentally regulated chromatin acetylation and histone H1(0) accumulation.
The International journal of developmental biology 1995;39(4):597-603.
1995: D Grunwald; J J Lawrence; Saadi Khochbin
Accumulation of histone H1(0) during early Xenopus laevis development.
Experimental cell research 1995;218(2):586-95.
1995: C Gorka; J J Lawrence; Saadi Khochbin
Variation of H1(0) content throughout the cell cycle in regenerating rat liver.
Experimental cell research 1995;217(2):528-33.
1994: Saadi Khochbin; A P Wolffe
Developmentally regulated expression of linker-histone variants in vertebrates.
European journal of biochemistry / FEBS 1994;225(2):501-10.
1994: G Almouzni; Saadi Khochbin; Stefan Dimitrov; Alan P Wolffe
Histone acetylation influences both gene expression and development of Xenopus laevis.
Developmental biology 1994;165(2):654-69.
1994: V Girardot; Thierry Rabilloud; M Yoshida; T Beppu; J J Lawrence; Saadi Khochbin
Relationship between core histone acetylation and histone H1(0) gene activity.
European journal of biochemistry / FEBS 1994;224(3):885-92.
1994: Saadi Khochbin; J J Lawrence
Molecular basis of the activation of basal histone H1(0) gene expression.
Nucleic acids research 1994;22(15):2887-93.
1994: Marie-Paule Brocard; D Rousseau; J J Lawrence; Saadi Khochbin
Two mRNA species encoding the differentiation-associated histone H1(0) are produced by alternative polyadenylation in mouse.
European journal of biochemistry / FEBS 1994;221(1):421-5.
1993: Saadi Khochbin; Alan P Wolffe
Developmental regulation and butyrate-inducible transcription of the Xenopus histone H1(0) promoter.
Gene 1993;128(2):173-80.
1992: jacques Baudier; Christian Delphin; D Grunwald; Saadi Khochbin; J J Lawrence
Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11627-31.
1992: Saadi Khochbin; Marie-Paule Brocard; D Grunwald; J J Lawrence
Antisense RNA and p53 regulation in induced murine cell differentiation.
Annals of the New York Academy of Sciences 1992;660():77-87.
1992: D Rousseau; Saadi Khochbin; C Gorka; J J Lawrence
Induction of H1(0)-gene expression in B16 murine melanoma cells.
European journal of biochemistry / FEBS 1992;208(3):775-9.
1992: F Mencherini; Saadi Khochbin; A Chabanas; J J Lawrence
Seric factors influence cell cycle modifications during commitment of murine erythroleukemia cells to differentiation.
Cytometry 1992;13(5):518-24.
1991: D Grunwald; Saadi Khochbin; J J Lawrence
Cell cycle-related accumulation of H1(0) mRNA: induction in murine erythroleukemia cells.
Experimental cell research 1991;194(2):174-9.
1991: Saadi Khochbin; C Gorka; J J Lawrence
Multiple control level governing H10 mRNA and protein accumulation.
FEBS letters 1991;283(1):65-7.
1991: Saadi Khochbin; D Grunwald; E Bergeret; J J Lawrence
Modulation of B2 containing small RNAs during induced differentiation of murine erythroleukemia cells.
Biochemical and biophysical research communications 1991;175(1):91-7.
1991: D Rousseau; Saadi Khochbin; C Gorka; J J Lawrence
Regulation of histone H1(0) accumulation during induced differentiation of murine erythroleukemia cells.
Journal of molecular biology 1991;217(1):85-92.
1990: Saadi Khochbin; D Grunwald; Michel Pabion; J J Lawrence
Recovery of RNA from flow-sorted fixed cells.
Cytometry 1990;11(8):869-74.
1989: Saadi Khochbin; J J Lawrence
An antisense RNA involved in p53 mRNA maturation in murine erythroleukemia cells induced to differentiate.
The EMBO journal 1989;8(13):4107-14.
1989: Saadi Khochbin; A Chabanas; P Albert; J J Lawrence
Flow cytofluorimetric determination of protein distribution throughout the cell cycle.
Cytometry 1989;10(4):484-9.
1988: Saadi Khochbin; A Chabanas; J J Lawrence
Early events in murine erythroleukemia cells induced to differentiate: variation of the cell cycle parameters in relation to p53 accumulation.
Experimental cell research 1988;179(2):565-74.
1988: Saadi Khochbin; A Chabanas; P Albert; J Albert; J J Lawrence
Application of bromodeoxyuridine incorporation measurements to the determination of cell distribution within the S phase of the cell cycle.
Cytometry 1988;9(5):499-503.
1988: Saadi Khochbin; E Principaud; A Chabanas; J J Lawrence
Early events in murine erythroleukemia cells induced to differentiate. Accumulation and gene expression of the transformation-associated cellular protein p53.
Journal of molecular biology 1988;200(1):55-64.