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Gobind Khorana

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Co-Publications
Name
27
Hubbell, Wayne
27
Reeves, Philip
25
Rothschild, Kenneth
23
Mogi, Tatsushi
21
Altenbach, Christian
20
Heyn, Maarten
19
Stern, Lawrence
18
Klein-Seetharaman, Judith
12
Cai, K
10
Hwa, John
10
Otto, Harald
10
RajBhandary, Uttam
9
Getmanova, Elena
9
Takagaki, Yohtaroh
8
Karnik, Sadashiva

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Publications

TOP 3
Ahuja Shivani; Crocker Evan; Eilers Markus; Hornak Viktor; Hirshfeld Amiram; Ziliox Martine; Syrett Natalie; Reeves Philip J; Khorana H Gobind; Sheves Mordechai; Smith Steven O
Location of the retinal chromophore in the activated state of rhodopsin*.
Takayama Hidehito; Chelikani Prashen; Reeves Philip J; Zhang Shuguang; Khorana H Gobind
High-level expression, single-step immunoaffinity purification and characterization of human tetraspanin membrane protein CD81.
McKibbin Craig; Farmer Nicola A; Jeans Chris; Reeves Philip J; Khorana H Gobind; Wallace B A; Edwards Patricia C; Villa Claudio; Booth Paula J
Opsin stability and folding: modulation by phospholipid bicelles.

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All Publications

2009: Ahuja Shivani; Crocker Evan; Eilers Markus; Hornak Viktor; Hirshfeld Amiram; Ziliox Martine; Syrett Natalie; Reeves Philip J; Khorana H Gobind; Sheves Mordechai; Smith Steven O
Location of the retinal chromophore in the activated state of rhodopsin*.
The Journal of biological chemistry 2009;284(15):10190-201.
2008: Takayama Hidehito; Chelikani Prashen; Reeves Philip J; Zhang Shuguang; Khorana H Gobind
High-level expression, single-step immunoaffinity purification and characterization of human tetraspanin membrane protein CD81.
PloS one 2008;3(6):e2314.
2007: McKibbin Craig; Farmer Nicola A; Jeans Chris; Reeves Philip J; Khorana H Gobind; Wallace B A; Edwards Patricia C; Villa Claudio; Booth Paula J
Opsin stability and folding: modulation by phospholipid bicelles.
Journal of molecular biology 2007;374(5):1319-32.
2007: McKibbin Craig; Toye Ashley M; Reeves Philip J; Khorana H Gobind; Edwards Patricia C; Villa Claudio; Booth Paula J
Opsin stability and folding: the role of Cys185 and abnormal disulfide bond formation in the intradiscal domain.
Journal of molecular biology 2007;374(5):1309-18.
2007: Chelikani Prashen; Hornak Viktor; Eilers Markus; Reeves Phillip J; Smith Steven O; RajBhandary Uttam L; Khorana H Gobind
Role of group-conserved residues in the helical core of beta2-adrenergic receptor.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(17):7027-32.
2007: Werner Karla; Lehner Ines; Dhiman Harpreet Kaur; Richter Christian; Glaubitz Clemens; Schwalbe Harald; Klein-Seetharaman Judith; Khorana H Gobind
Combined solid state and solution NMR studies of alpha,epsilon-15N labeled bovine rhodopsin.
Journal of biomolecular NMR 2007;37(4):303-12.
2006: Zhao Xiaojun; Nagai Yusuke; Reeves Philip J; Kiley Patrick; Khorana H Gobind; Zhang Shuguang
Designer short peptide surfactants stabilize G protein-coupled receptor bovine rhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(47):17707-12.
2006: Chelikani Prashen; Reeves Philip J; Rajbhandary Uttam L; Khorana H Gobind
The synthesis and high-level expression of a beta2-adrenergic receptor gene in a tetracycline-inducible stable mammalian cell line.
Protein science : a publication of the Protein Society 2006;15(6):1433-40.
2006: Kota Parvathi; Reeves Philip J; Rajbhandary Uttam L; Khorana H Gobind
Opsin is present as dimers in COS1 cells: identification of amino acids at the dimeric interface.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3054-9.
2005: Patel Ashish B; Crocker Evan; Reeves Philip J; Getmanova Elena V; Eilers Markus; Khorana H Gobind; Smith Steven O
Changes in interhelical hydrogen bonding upon rhodopsin activation.
Journal of molecular biology 2005;347(4):803-12.
2005: Kim Jong-Myoung; Hwa John; Garriga Pere; Reeves Philip J; RajBhandary Uttam L; Khorana H Gobind
Light-driven activation of beta 2-adrenergic receptor signaling by a chimeric rhodopsin containing the beta 2-adrenergic receptor cytoplasmic loops.
Biochemistry 2005;44(7):2284-92.
2004: Kim Jong-Myoung; Altenbach Christian; Kono Masahiro; Oprian Daniel D; Hubbell Wayne L; Khorana H Gobind
Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(34):12508-13.
2004: Rader A J; Anderson Gülsüm; Isin Basak; Khorana H Gobind; Bahar Ivet; Klein-Seetharaman Judith
Identification of core amino acids stabilizing rhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(19):7246-51.
2004: Crocker Evan; Patel Ashish B; Eilers Markus; Jayaraman Shobini; Getmanova Elena; Reeves Philip J; Ziliox Martine; Khorana H Gobind; Sheves Mordechai; Smith Steven O
Dipolar assisted rotational resonance NMR of tryptophan and tyrosine in rhodopsin.
Journal of biomolecular NMR 2004;29(1):11-20.
2004: Klein-Seetharaman Judith; Yanamala Naveena V K; Javeed Fathima; Reeves Philip J; Getmanova Elena V; Loewen Michele C; Schwalbe Harald; Khorana H Gobind
Differential dynamics in the G protein-coupled receptor rhodopsin revealed by solution NMR.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(10):3409-13.
2004: Getmanova Elena; Patel Ashish B; Klein-Seetharaman Judith; Loewen Michele C; Reeves Philip J; Friedman Noga; Sheves Mordechai; Smith Steven O; Khorana H Gobind
NMR spectroscopy of phosphorylated wild-type rhodopsin: mobility of the phosphorylated C-terminus of rhodopsin in the dark and upon light activation.
Biochemistry 2004;43(4):1126-33.
2003: Stojanovic Aleksandar; Hwang Irene; Khorana Har Gobind; Hwa John
Retinitis pigmentosa rhodopsin mutations L125R and A164V perturb critical interhelical interactions: new insights through compensatory mutations and crystal structure analysis.
The Journal of biological chemistry 2003;278(40):39020-8.
2003: Hubbell Wayne L; Altenbach Christian; Hubbell Cheryl M; Khorana H Gobind
Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking.
Advances in protein chemistry 2003;63():243-90.
2002: Reeves Philip J; Callewaert Nico; Contreras Roland; Khorana H Gobind
Structure and function in rhodopsin: high-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13419-24.
2002: Reeves Philip J; Kim Jong-Myoung; Khorana H Gobind
Structure and function in rhodopsin: a tetracycline-inducible system in stable mammalian cell lines for high-level expression of opsin mutants.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13413-8.
2002: Niu Li; Kim Jong-Myoung; Khorana H Gobind
Structure and function in rhodopsin: asymmetric reconstitution of rhodopsin in liposomes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13409-12.
2002: Klein-Seetharaman J; Reeves P J; Loewen M C; Getmanova E V; Chung J; Schwalbe H; Wright P E; Khorana H G
Solution NMR spectroscopy of [alpha -15N]lysine-labeled rhodopsin: The single peak observed in both conventional and TROSY-type HSQC spectra is ascribed to Lys-339 in the carboxyl-terminal peptide sequence.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3452-7.
2002: Eilers Markus; Ying Weiwen; Reeves Philip J; Khorana H Gobind; Smith Steven O
Magic angle spinning nuclear magnetic resonance of isotopically labeled rhodopsin.
Methods in enzymology 2002;343():212-22.
2001: Altenbach C; Klein-Seetharaman J; Cai K; Khorana H G; Hubbell W L
Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 316 in helix 8 and residues in the sequence 60-75, covering the cytoplasmic end of helices TM1 and TM2 and their connection loop CL1.
Biochemistry 2001;40(51):15493-500.
2001: Altenbach C; Cai K; Klein-Seetharaman J; Khorana H G; Hubbell W L
Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 65 in helix TM1 and residues in the sequence 306-319 at the cytoplasmic end of helix TM7 and in helix H8.
Biochemistry 2001;40(51):15483-92.
2001: Cai K; Klein-Seetharaman J; Altenbach C; Hubbell W L; Khorana H G
Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between cysteine pairs engineered in cytoplasmic loops 1, 3, and 4.
Biochemistry 2001;40(42):12479-85.
2001: Klein-Seetharaman J; Hwa J; Cai K; Altenbach C; Hubbell W L; Khorana H G
Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between Cys316 and engineered cysteines in cytoplasmic loop 1.
Biochemistry 2001;40(42):12472-8.
2001: Allen S J; Kim J M; Khorana H G; Lu H; Booth P J
Structure and function in bacteriorhodopsin: the effect of the interhelical loops on the protein folding kinetics.
Journal of molecular biology 2001;308(2):423-35.
2001: Kim J M; Booth P J; Allen S J; Khorana H G
Structure and function in bacteriorhodopsin: the role of the interhelical loops in the folding and stability of bacteriorhodopsin.
Journal of molecular biology 2001;308(2):409-22.
2001: Loewen M C; Klein-Seetharaman J; Getmanova E V; Reeves P J; Schwalbe H; Khorana H G
Solution 19F nuclear Overhauser effects in structural studies of the cytoplasmic domain of mammalian rhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(9):4888-92.
2001: Itoh Y; Cai K; Khorana H G
Mapping of contact sites in complex formation between light-activated rhodopsin and transducin by covalent crosslinking: use of a chemically preactivated reagent.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(9):4883-7.
2001: Cai K; Itoh Y; Khorana H G
Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(9):4877-82.
2001: Hwa J; Klein-Seetharaman J; Khorana H G
Structure and function in rhodopsin: Mass spectrometric identification of the abnormal intradiscal disulfide bond in misfolded retinitis pigmentosa mutants.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(9):4872-6.
2000: Alexiev U; Mollaaghababa R; Khorana H G; Heyn M P
Evidence for long range allosteric interactions between the extracellular and cytoplasmic parts of bacteriorhodopsin from the mutant R82A and its second site revertant R82A/G231C.
The Journal of biological chemistry 2000;275(18):13431-40.
2000: Cha K; Reeves P J; Khorana H G
Structure and function in rhodopsin: destabilization of rhodopsin by the binding of an antibody at the N-terminal segment provides support for involvement of the latter in an intradiscal tertiary structure.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3016-21.
2000: Bruel C; Cha K; Niu L; Reeves P J; Khorana H G
Rhodopsin kinase: two mAbs binding near the carboxyl terminus cause time-dependent inactivation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3010-5.
2000: Bruel C; Cha K; Reeves P J; Getmanova E; Khorana H G
Rhodopsin kinase: expression in mammalian cells and a two-step purification.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3004-9.
2000: Khorana H G
A life in science.
Science (New York, N.Y.) 2000;287(5454):810.
2000: Mollaaghababa R; Steinhoff H J; Hubbell W L; Khorana H G
Time-resolved site-directed spin-labeling studies of bacteriorhodopsin: loop-specific conformational changes in M.
Biochemistry 2000;39(5):1120-7.
1999: Reeves P J; Klein-Seetharaman J; Getmanova E V; Eilers M; Loewen M C; Smith S O; Khorana H G
Expression and purification of rhodopsin and its mutants from stable mammalian cell lines: application to NMR studies.
Biochemical Society transactions 1999;27(6):950-5.
1999: Klein-Seetharaman J; Getmanova E V; Loewen M C; Reeves P J; Khorana H G
NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13744-9.
1999: Cai K; Klein-Seetharaman J; Hwa J; Hubbell W L; Khorana H G
Structure and function in rhodopsin: effects of disulfide cross-links in the cytoplasmic face of rhodopsin on transducin activation and phosphorylation by rhodopsin kinase.
Biochemistry 1999;38(39):12893-8.
1999: Altenbach C; Klein-Seetharaman J; Hwa J; Khorana H G; Hubbell W L
Structural features and light-dependent changes in the sequence 59-75 connecting helices I and II in rhodopsin: a site-directed spin-labeling study.
Biochemistry 1999;38(25):7945-9.
1999: Klein-Seetharaman J; Hwa J; Cai K; Altenbach C; Hubbell W L; Khorana H G
Single-cysteine substitution mutants at amino acid positions 55-75, the sequence connecting the cytoplasmic ends of helices I and II in rhodopsin: reactivity of the sulfhydryl groups and their derivatives identifies a tertiary structure that changes upon light-activation.
Biochemistry 1999;38(25):7938-44.
1999: Altenbach C; Cai K; Khorana H G; Hubbell W L
Structural features and light-dependent changes in the sequence 306-322 extending from helix VII to the palmitoylation sites in rhodopsin: a site-directed spin-labeling study.
Biochemistry 1999;38(25):7931-7.
1999: Cai K; Klein-Seetharaman J; Farrens D; Zhang C; Altenbach C; Hubbell W L; Khorana H G
Single-cysteine substitution mutants at amino acid positions 306-321 in rhodopsin, the sequence between the cytoplasmic end of helix VII and the palmitoylation sites: sulfhydryl reactivity and transducin activation reveal a tertiary structure.
Biochemistry 1999;38(25):7925-30.
1999: Langen R; Cai K; Altenbach C; Khorana H G; Hubbell W L
Structural features of the C-terminal domain of bovine rhodopsin: a site-directed spin-labeling study.
Biochemistry 1999;38(25):7918-24.
1999: Hwa J; Reeves P J; Klein-Seetharaman J; Davidson F; Khorana H G
Structure and function in rhodopsin: further elucidation of the role of the intradiscal cysteines, Cys-110, -185, and -187, in rhodopsin folding and function.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):1932-5.
1999: Reeves P J; Hwa J; Khorana H G
Structure and function in rhodopsin: kinetic studies of retinal binding to purified opsin mutants in defined phospholipid-detergent mixtures serve as probes of the retinal binding pocket.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):1927-31.
1999: Eilers M; Reeves P J; Ying W; Khorana H G; Smith S O
Magic angle spinning NMR of the protonated retinylidene Schiff base nitrogen in rhodopsin: expression of 15N-lysine- and 13C-glycine-labeled opsin in a stable cell line.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(2):487-92.
1998: Behrens W; Alexiev U; Mollaaghababa R; Khorana H G; Heyn M P
Structure of the interhelical loops and carboxyl terminus of bacteriorhodopsin by X-ray diffraction using site-directed heavy-atom labeling.
Biochemistry 1998;37(29):10411-9.
1998: Khorana H G
Research programs in Japan.
Japanese journal of clinical oncology 1998;28(2):152.
1997: Kim J M; Altenbach C; Thurmond R L; Khorana H G; Hubbell W L
Structure and function in rhodopsin: rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14273-8.
1997: Cai K; Langen R; Hubbell W L; Khorana H G
Structure and function in rhodopsin: topology of the C-terminal polypeptide chain in relation to the cytoplasmic loops.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14267-72.
1997: Cha K; Bruel C; Inglese J; Khorana H G
Rhodopsin kinase: expression in baculovirus-infected insect cells, and characterization of post-translational modifications.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(20):10577-82.
1997: Hwa J; Garriga P; Liu X; Khorana H G
Structure and function in rhodopsin: packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(20):10571-6.
1997: Thurmond R L; Creuzenet C; Reeves P J; Khorana H G
Structure and function in rhodopsin: peptide sequences in the cytoplasmic loops of rhodopsin are intimately involved in interaction with rhodopsin kinase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(5):1715-20.
1996: Yang K; Farrens D L; Altenbach C; Farahbakhsh Z T; Hubbell W L; Khorana H G
Structure and function in rhodopsin. Cysteines 65 and 316 are in proximity in a rhodopsin mutant as indicated by disulfide formation and interactions between attached spin labels.
Biochemistry 1996;35(45):14040-6.
1996: Farrens D L; Altenbach C; Yang K; Hubbell W L; Khorana H G
Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin.
Science (New York, N.Y.) 1996;274(5288):768-70.
1996: Reeves P J; Thurmond R L; Khorana H G
Structure and function in rhodopsin: high level expression of a synthetic bovine opsin gene and its mutants in stable mammalian cell lines.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11487-92.
1996: Mollaaghababa R; Davidson F F; Kaiser C; Khorana H G
Structure and function in rhodopsin: expression of functional mammalian opsin in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11482-6.
1996: Altenbach C; Yang K; Farrens D L; Farahbakhsh Z T; Khorana H G; Hubbell W L
Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study.
Biochemistry 1996;35(38):12470-8.
1996: Yang K; Farrens D L; Hubbell W L; Khorana H G
Structure and function in rhodopsin. Single cysteine substitution mutants in the cytoplasmic interhelical E-F loop region show position-specific effects in transducin activation.
Biochemistry 1996;35(38):12464-9.
1996: Garriga P; Liu X; Khorana H G
Structure and function in rhodopsin: correct folding and misfolding in point mutants at and in proximity to the site of the retinitis pigmentosa mutation Leu-125-->Arg in the transmembrane helix C.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):4560-4.
1996: Liu X; Garriga P; Khorana H G
Structure and function in rhodopsin: correct folding and misfolding in two point mutants in the intradiscal domain of rhodopsin identified in retinitis pigmentosa.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):4554-9.
1995: Dickopf S; Alexiev U; Krebs M P; Otto H; Mollaaghababa R; Khorana H G; Heyn M P
Proton transport by a bacteriorhodopsin mutant, aspartic acid-85-->asparagine, initiated in the unprotonated Schiff base state.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(25):11519-23.
1995: Moltke S; Krebs M P; Mollaaghababa R; Khorana H G; Heyn M P
Intramolecular charge transfer in the bacteriorhodopsin mutants Asp85-->Asn and Asp212-->Asn: effects of pH and anions.
Biophysical journal 1995;69(5):2074-83.
1995: Alexiev U; Scherrer P; Marti T; Khorana H G; Heyn M P
Time-resolved surface charge change on the cytoplasmic side of bacteriorhodopsin.
FEBS letters 1995;373(1):81-4.
1995: Steinhoff H J; Mollaaghababa R; Altenbach C; Khorana H G; Hubbell W L
Site directed spin labeling studies of structure and dynamics in bacteriorhodopsin.
Biophysical chemistry 1995;56(1-2):89-94.
1995: Farahbakhsh Z T; Ridge K D; Khorana H G; Hubbell W L
Mapping light-dependent structural changes in the cytoplasmic loop connecting helices C and D in rhodopsin: a site-directed spin labeling study.
Biochemistry 1995;34(27):8812-9.
1995: Ridge K D; Zhang C; Khorana H G
Mapping of the amino acids in the cytoplasmic loop connecting helices C and D in rhodopsin. Chemical reactivity in the dark state following single cysteine replacements.
Biochemistry 1995;34(27):8804-11.
1995: Farrens D L; Khorana H G
Structure and function in rhodopsin. Measurement of the rate of metarhodopsin II decay by fluorescence spectroscopy.
The Journal of biological chemistry 1995;270(10):5073-6.
1995: Ridge K D; Lu Z; Liu X; Khorana H G
Structure and function in rhodopsin. Separation and characterization of the correctly folded and misfolded opsins produced on expression of an opsin mutant gene containing only the native intradiscal cysteine codons.
Biochemistry 1995;34(10):3261-7.
1995: Booth P J; Flitsch S L; Stern L J; Greenhalgh D A; Kim P S; Khorana H G
Intermediates in the folding of the membrane protein bacteriorhodopsin.
Nature structural biology 1995;2(2):139-43.
1995: Alexiev U; Mollaaghababa R; Scherrer P; Khorana H G; Heyn M P
Rapid long-range proton diffusion along the surface of the purple membrane and delayed proton transfer into the bulk.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(2):372-6.
1995: Sakamoto T; Khorana H G
Structure and function in rhodopsin: the fate of opsin formed upon the decay of light-activated metarhodopsin II in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(1):249-53.
1994: Sonar S; Marti T; Rath P; Fischer W; Coleman M; Nilsson A; Khorana H G; Rothschild K J
A redirected proton pathway in the bacteriorhodopsin mutant Tyr-57-->Asp. Evidence for proton translocation without Schiff base deprotonation.
The Journal of biological chemistry 1994;269(46):28851-8.
1994: Alexiev U; Marti T; Heyn M P; Khorana H G; Scherrer P
Covalently bound pH-indicator dyes at selected extracellular or cytoplasmic sites in bacteriorhodopsin. 2. Rotational orientation of helices D and E and kinetic correlation between M formation and proton release in bacteriorhodopsin micelles.
Biochemistry 1994;33(46):13693-9.
1994: Scherrer P; Alexiev U; Marti T; Khorana H G; Heyn M P
Covalently bound pH-indicator dyes at selected extracellular or cytoplasmic sites in bacteriorhodopsin. 1. Proton migration along the surface of bacteriorhodopsin micelles and its delayed transfer from surface to bulk.
Biochemistry 1994;33(46):13684-92.
1994: Fischer W B; Sonar S; Marti T; Khorana H G; Rothschild K J
Detection of a water molecule in the active-site of bacteriorhodopsin: hydrogen bonding changes during the primary photoreaction.
Biochemistry 1994;33(43):12757-62.
1994: Steinhoff H J; Mollaaghababa R; Altenbach C; Hideg K; Krebs M; Khorana H G; Hubbell W L
Time-resolved detection of structural changes during the photocycle of spin-labeled bacteriorhodopsin.
Science (New York, N.Y.) 1994;266(5182):105-7.
1994: Resek J F; Farrens D; Khorana H G
Structure and function in rhodopsin: covalent crosslinking of the rhodopsin (metarhodopsin II)-transducin complex--the rhodopsin cytoplasmic face links to the transducin alpha subunit.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(16):7643-7.
1994: Anukanth A; Khorana H G
Structure and function in rhodopsin. Requirements of a specific structure for the intradiscal domain.
The Journal of biological chemistry 1994;269(31):19738-44.
1994: Sonar S; Lee C P; Coleman M; Patel N; Liu X; Marti T; Khorana H G; RajBhandary U L; Rothschild K J
Site-directed isotope labelling and FTIR spectroscopy of bacteriorhodopsin.
Nature structural biology 1994;1(8):512-7.
1994: Kaushal S; Khorana H G
Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa.
Biochemistry 1994;33(20):6121-8.
1994: Davidson F F; Loewen P C; Khorana H G
Structure and function in rhodopsin: replacement by alanine of cysteine residues 110 and 187, components of a conserved disulfide bond in rhodopsin, affects the light-activated metarhodopsin II state.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):4029-33.
1994: Kaushal S; Ridge K D; Khorana H G
Structure and function in rhodopsin: the role of asparagine-linked glycosylation.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):4024-8.
1994: Altenbach C; Greenhalgh D A; Khorana H G; Hubbell W L
A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(5):1667-71.
1994: Alexiev U; Marti T; Heyn M P; Khorana H G; Scherrer P
Surface charge of bacteriorhodopsin detected with covalently bound pH indicators at selected extracellular and cytoplasmic sites.
Biochemistry 1994;33(1):298-306.
1993: Rothschild K J; Marti T; Sonar S; He Y W; Rath P; Fischer W; Khorana H G
Asp96 deprotonation and transmembrane alpha-helical structural changes in bacteriorhodopsin.
The Journal of biological chemistry 1993;268(36):27046-52.
1993: Krebs M P; Behrens W; Mollaaghababa R; Khorana H G; Heyn M P
X-ray diffraction of a cysteine-containing bacteriorhodopsin mutant and its mercury derivative. Localization of an amino acid residue in the loop of an integral membrane protein.
Biochemistry 1993;32(47):12830-4.
1993: Resek J F; Farahbakhsh Z T; Hubbell W L; Khorana H G
Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin.
Biochemistry 1993;32(45):12025-32.
1993: Greenhalgh D A; Farrens D L; Subramaniam S; Khorana H G
Hydrophobic amino acids in the retinal-binding pocket of bacteriorhodopsin.
The Journal of biological chemistry 1993;268(27):20305-11.
1993: Rath P; Marti T; Sonar S; Khorana H G; Rothschild K J
Hydrogen bonding interactions with the Schiff base of bacteriorhodopsin. Resonance Raman spectroscopy of the mutants D85N and D85A.
The Journal of biological chemistry 1993;268(24):17742-9.
1993: Knox B E; Khorana H G; Nasi E
Light-induced currents in Xenopus oocytes expressing bovine rhodopsin.
The Journal of physiology 1993;466():157-72.
1993: Zhang Y N; el-Sayed M A; Stern L J; Marti T; Mogi T; Khorana H G
Effects of mutagenetic substitution of prolines on the rate of deprotonation and reprotonation of the Schiff base during the photocycle of bacteriorhodopsin.
Photochemistry and photobiology 1993;57(6):1027-31.
1993: Krebs M P; Spudich E N; Khorana H G; Spudich J L
Synthesis of a gene for sensory rhodopsin I and its functional expression in Halobacterium halobium.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3486-90.
1993: Krebs M P; Mollaaghababa R; Khorana H G
Gene replacement in Halobacterium halobium and expression of bacteriorhodopsin mutants.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(5):1987-91.
1993: He Y; Krebs M P; Fischer W B; Khorana H G; Rothschild K J
FTIR difference spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: detection of a stable O-like species and characterization of its photocycle at low temperature.
Biochemistry 1993;32(9):2282-90.
1993: Rath P; Krebs M P; He Y; Khorana H G; Rothschild K J
Fourier transform Raman spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: formation of a stable O-like species during light adaptation and detection of its transient N-like photoproduct.
Biochemistry 1993;32(9):2272-81.
1993: Sonar S; Krebs M P; Khorana H G; Rothschild K J
Static and time-resolved absorption spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: evidence for an equilibrium between bR570 and an O-like species.
Biochemistry 1993;32(9):2263-71.
1993: Krebs M P; Khorana H G
Mechanism of light-dependent proton translocation by bacteriorhodopsin.
Journal of bacteriology 1993;175(6):1555-60.
1993: Khorana H G
Two light-transducing membrane proteins: bacteriorhodopsin and the mammalian rhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(4):1166-71.
1993: Karnik S S; Ridge K D; Bhattacharya S; Khorana H G
Palmitoylation of bovine opsin and its cysteine mutants in COS cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):40-4.
1993: Khorana H G
Signal transduction in two light-transducing systems: bacteriorhodopsin and mammalian rhodopsin.
Nucleic acids symposium series 1993;(29):219.
1992: Subramaniam S; Greenhalgh D A; Khorana H G
Aspartic acid 85 in bacteriorhodopsin functions both as proton acceptor and negative counterion to the Schiff base.
The Journal of biological chemistry 1992;267(36):25730-3.
1992: Greenhalgh D A; Subramaniam S; Alexiev U; Otto H; Heyn M P; Khorana H G
Effect of introducing different carboxylate-containing side chains at position 85 on chromophore formation and proton transport in bacteriorhodopsin.
The Journal of biological chemistry 1992;267(36):25734-8.
1992: Bousché O; Sonar S; Krebs M P; Khorana H G; Rothschild K J
Time-resolved Fourier transform infrared spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: Asp-96 reprotonates during O formation; Asp-85 and Asp-212 deprotonate during O decay.
Photochemistry and photobiology 1992;56(6):1085-95.
1992: Marti T; Otto H; Rösselet S J; Heyn M P; Khorana H G
Anion binding to the Schiff base of the bacteriorhodopsin mutants Asp-85----Asn/Asp-212----Asn and Arg-82----Gln/Asp-85----Asn/Asp-212----Asn.
The Journal of biological chemistry 1992;267(24):16922-7.
1992: Franke R R; Sakmar T P; Graham R M; Khorana H G
Structure and function in rhodopsin. Studies of the interaction between the rhodopsin cytoplasmic domain and transducin.
The Journal of biological chemistry 1992;267(21):14767-74.
1992: Lin S W; Sakmar T P; Franke R R; Khorana H G; Mathies R A
Resonance Raman microprobe spectroscopy of rhodopsin mutants: effect of substitutions in the third transmembrane helix.
Biochemistry 1992;31(22):5105-11.
1992: Wu S; Chang Y; el-Sayed M A; Marti T; Mogi T; Khorana H G
Effects of tryptophan mutation on the deprotonation and reprotonation kinetics of the Schiff base during the photocycle of bacteriorhodopsin.
Biophysical journal 1992;61(5):1281-8.
1992: Bhattacharya S; Ridge K D; Knox B E; Khorana H G
Light-stable rhodopsin. I. A rhodopsin analog reconstituted with a nonisomerizable 11-cis retinal derivative.
The Journal of biological chemistry 1992;267(10):6763-9.
1992: Bhattacharya S; Marti T; Otto H; Heyn M P; Khorana H G
A bacteriorhodopsin analog reconstituted with a nonisomerizable 13-trans retinal derivative displays light insensitivity.
The Journal of biological chemistry 1992;267(10):6757-62.
1992: Ridge K D; Bhattacharya S; Nakayama T A; Khorana H G
Light-stable rhodopsin. II. An opsin mutant (TRP-265----Phe) and a retinal analog with a nonisomerizable 11-cis configuration form a photostable chromophore.
The Journal of biological chemistry 1992;267(10):6770-5.
1992: Marti T; Otto H; Rösselet S J; Heyn M P; Khorana H G
Consequences of amino acid insertions and/or deletions in transmembrane helix C of bacteriorhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1219-23.
1992: Rothschild K J; He Y W; Sonar S; Marti T; Khorana H G
Vibrational spectroscopy of bacteriorhodopsin mutants. Evidence that Thr-46 and Thr-89 form part of a transient network of hydrogen bonds.
The Journal of biological chemistry 1992;267(3):1615-22.
1992: Khorana H G
Rhodopsin, photoreceptor of the rod cell. An emerging pattern for structure and function.
The Journal of biological chemistry 1992;267(1):1-4.
1992: Sgaramella V; Khorana H G
A further study of the T4 ligase-catalyzed joining of DNA at base-paired ends. 1972.
Biotechnology (Reading, Mass.) 1992;24():28-37.
1991: Marti T; Rösselet S J; Otto H; Heyn M P; Khorana H G
The retinylidene Schiff base counterion in bacteriorhodopsin.
The Journal of biological chemistry 1991;266(28):18674-83.
1991: Greenhalgh D A; Altenbach C; Hubbell W L; Khorana H G
Locations of Arg-82, Asp-85, and Asp-96 in helix C of bacteriorhodopsin relative to the aqueous boundaries.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8626-30.
1991: Subramaniam S; Greenhalgh D A; Rath P; Rothschild K J; Khorana H G
Replacement of leucine-93 by alanine or threonine slows down the decay of the N and O intermediates in the photocycle of bacteriorhodopsin: implications for proton uptake and 13-cis-retinal----all-trans-retinal reisomerization.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6873-7.
1991: Lin G C; el-Sayed M A; Marti T; Stern L J; Mogi T; Khorana H G
Effects of individual genetic substitutions of arginine residues on the deprotonation and reprotonation kinetics of the Schiff base during the bacteriorhodopsin photocycle.
Biophysical journal 1991;60(1):172-8.
1991: Bousché O; Braiman M; He Y W; Marti T; Khorana H G; Rothschild K J
Vibrational spectroscopy of bacteriorhodopsin mutants. Evidence that ASP-96 deprotonates during the M----N transition.
The Journal of biological chemistry 1991;266(17):11063-7.
1991: Gilles-Gonzalez M A; Engelman D M; Khorana H G
Structure-function studies of bacteriorhodopsin XV. Effects of deletions in loops B-C and E-F on bacteriorhodopsin chromophore and structure.
The Journal of biological chemistry 1991;266(13):8545-50.
1991: Sugimoto Y; Yatsunami K; Tsujimoto M; Khorana H G; Ichikawa A
The amino acid sequence of a glutamic acid-rich protein from bovine retina as deduced from the cDNA sequence.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3116-9.
1991: Sakmar T P; Franke R R; Khorana H G
The role of the retinylidene Schiff base counterion in rhodopsin in determining wavelength absorbance and Schiff base pKa.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3079-83.
1991: Marti T; Otto H; Mogi T; Rösselet S J; Heyn M P; Khorana H G
Bacteriorhodopsin mutants containing single substitutions of serine or threonine residues are all active in proton translocation.
The Journal of biological chemistry 1991;266(11):6919-27.
1991: Subramaniam S; Marti T; Rösselet S J; Rothschild K J; Khorana H G
The reaction of hydroxylamine with bacteriorhodopsin studied with mutants that have altered photocycles: selective reactivity of different photointermediates.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2583-7.
1991: Nakayama T A; Khorana H G
Mapping of the amino acids in membrane-embedded helices that interact with the retinal chromophore in bovine rhodopsin.
The Journal of biological chemistry 1991;266(7):4269-75.
1991: Krebs M P; Hauss T; Heyn M P; RajBhandary U L; Khorana H G
Expression of the bacterioopsin gene in Halobacterium halobium using a multicopy plasmid.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(3):859-63.
1990: Duñach M; Marti T; Khorana H G; Rothschild K J
Uv-visible spectroscopy of bacteriorhodopsin mutants: substitution of Arg-82, Asp-85, Tyr-185, and Asp-212 results in abnormal light-dark adaptation.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9873-7.
1990: Karnik S; Doi T; Molday R; Khorana H G
Expression of the archaebacterial bacterio-opsin gene with and without signal sequences in Escherichia coli: the expressed proteins are located in the membrane but bind retinal poorly.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(22):8955-9.
1990: Krebs M P; RajBhandary U L; Khorana H G
Nucleotide sequence of ISH11, a new Halobacterium halobium insertion element isolated from the plasmid pGRB1.
Nucleic acids research 1990;18(22):6699.
1990: Franke R R; König B; Sakmar T P; Khorana H G; Hofmann K P
Rhodopsin mutants that bind but fail to activate transducin.
Science (New York, N.Y.) 1990;250(4977):123-5.
1990: Rothschild K J; Braiman M S; He Y W; Marti T; Khorana H G
Vibrational spectroscopy of bacteriorhodopsin mutants. Evidence for the interaction of aspartic acid 212 with tyrosine 185 and possible role in the proton pump mechanism.
The Journal of biological chemistry 1990;265(28):16985-91.
1990: Duñach M; Berkowitz S; Marti T; He Y W; Subramaniam S; Khorana H G; Rothschild K J
Ultraviolet-visible transient spectroscopy of bacteriorhodopsin mutants. Evidence for two forms of tyrosine-185----phenylalanine.
The Journal of biological chemistry 1990;265(28):16978-84.
1990: Karnik S S; Khorana H G
Assembly of functional rhodopsin requires a disulfide bond between cysteine residues 110 and 187.
The Journal of biological chemistry 1990;265(29):17520-4.
1990: Nakayama T A; Khorana H G
Orientation of retinal in bovine rhodopsin determined by cross-linking using a photoactivatable analog of 11-cis-retinal.
The Journal of biological chemistry 1990;265(26):15762-9.
1990: Bubis J; Khorana H G
Sites of interaction in the complex between beta- and gamma-subunits of transducin.
The Journal of biological chemistry 1990;265(22):12995-9.
1990: Doi T; Molday R S; Khorana H G
Role of the intradiscal domain in rhodopsin assembly and function.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(13):4991-5.
1990: Hackett N R; Krebs M P; DasSarma S; Goebel W; RajBhandary U L; Khorana H G
Nucleotide sequence of a high copy number plasmid from Halobacterium strain GRB.
Nucleic acids research 1990;18(11):3408.
1990: Jang D J; el-Sayed M A; Stern L J; Mogi T; Khorana H G
Effect of genetic modification of tyrosine-185 on the proton pump and the blue-to-purple transition in bacteriorhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(11):4103-7.
1990: Rothschild K J; He Y W; Mogi T; Marti T; Stern L J; Khorana H G
Vibrational spectroscopy of bacteriorhodopsin mutants: evidence for the interaction of proline-186 with the retinylidene chromophore.
Biochemistry 1990;29(25):5954-60.
1990: Altenbach C; Marti T; Khorana H G; Hubbell W L
Transmembrane protein structure: spin labeling of bacteriorhodopsin mutants.
Science (New York, N.Y.) 1990;248(4959):1088-92.
1990: Du J J; el-Sayed M A; Stern L J; Mogi T; Khorana H G
Sensitivity of the retinal circular dichroism of bacteriorhodopsin to the mutagenetic single substitution of amino acids: tyrosine.
FEBS letters 1990;262(2):155-8.
1990: Thompson D A; Khorana H G
Guanosine 3',5'-cyclic nucleotide binding proteins of bovine retina identified by photoaffinity labeling.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(6):2201-5.
1990: Otto H; Marti T; Holz M; Mogi T; Stern L J; Engel F; Khorana H G; Heyn M P
Substitution of amino acids Asp-85, Asp-212, and Arg-82 in bacteriorhodopsin affects the proton release phase of the pump and the pK of the Schiff base.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(3):1018-22.
1990: Subramaniam S; Marti T; Khorana H G
Protonation state of Asp (Glu)-85 regulates the purple-to-blue transition in bacteriorhodopsin mutants Arg-82----Ala and Asp-85----Glu: the blue form is inactive in proton translocation.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(3):1013-7.
1989: Stern L J; Ahl P L; Marti T; Mogi T; Duñach M; Berkowitz S; Rothschild K J; Khorana H G
Substitution of membrane-embedded aspartic acids in bacteriorhodopsin causes specific changes in different steps of the photochemical cycle.
Biochemistry 1989;28(26):10035-42.
1989: Ahl P L; Stern L J; Mogi T; Khorana H G; Rothschild K J
Substitution of amino acids in helix F of bacteriorhodopsin: effects on the photochemical cycle.
Biochemistry 1989;28(26):10028-34.
1989: Otto H; Marti T; Holz M; Mogi T; Lindau M; Khorana H G; Heyn M P
Aspartic acid-96 is the internal proton donor in the reprotonation of the Schiff base of bacteriorhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(23):9228-32.
1989: Sakmar T P; Franke R R; Khorana H G
Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8309-13.
1989: Flitsch S L; Khorana H G
Structural studies on transmembrane proteins. 1. Model study using bacteriorhodopsin mutants containing single cysteine residues.
Biochemistry 1989;28(19):7800-5.
1989: Altenbach C; Flitsch S L; Khorana H G; Hubbell W L
Structural studies on transmembrane proteins. 2. Spin labeling of bacteriorhodopsin mutants at unique cysteines.
Biochemistry 1989;28(19):7806-12.
1989: Rothschild K J; Gray D; Mogi T; Marti T; Braiman M S; Stern L J; Khorana H G
Vibrational spectroscopy of bacteriorhodopsin mutants: chromophore isomerization perturbs tryptophan-86.
Biochemistry 1989;28(17):7052-9.
1989: Stern L J; Khorana H G
Structure-function studies on bacteriorhodopsin. X. Individual substitutions of arginine residues by glutamine affect chromophore formation, photocycle, and proton translocation.
The Journal of biological chemistry 1989;264(24):14202-8.
1989: Mogi T; Marti T; Khorana H G
Structure-function studies on bacteriorhodopsin. IX. Substitutions of tryptophan residues affect protein-retinal interactions in bacteriorhodopsin.
The Journal of biological chemistry 1989;264(24):14197-201.
1989: Mogi T; Stern L J; Chao B H; Khorana H G
Structure-function studies on bacteriorhodopsin. VIII. Substitutions of the membrane-embedded prolines 50, 91, and 186: the effects are determined by the substituting amino acids.
The Journal of biological chemistry 1989;264(24):14192-6.
1989: Rothschild K J; Braiman M S; Mogi T; Stern L J; Khorana H G
Conserved amino acids in F-helix of bacteriorhodopsin form part of a retinal binding pocket.
FEBS letters 1989;250(2):448-52.
1989: Holz M; Drachev L A; Mogi T; Otto H; Kaulen A D; Heyn M P; Skulachev V P; Khorana H G
Replacement of aspartic acid-96 by asparagine in bacteriorhodopsin slows both the decay of the M intermediate and the associated proton movement.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2167-71.
1989: Marinetti T; Subramaniam S; Mogi T; Marti T; Khorana H G
Replacement of aspartic residues 85, 96, 115, or 212 affects the quantum yield and kinetics of proton release and uptake by bacteriorhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(2):529-33.
1989: Brouillette C G; McMichens R B; Stern L J; Khorana H G
Structure and thermal stability of monomeric bacteriorhodopsin in mixed phospholipid/detergent micelles.
Proteins 1989;5(1):38-46.
1988: Karnik S S; Sakmar T P; Chen H B; Khorana H G
Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(22):8459-63.
1988: Khorana H G; Knox B E; Nasi E; Swanson R; Thompson D A
Expression of a bovine rhodopsin gene in Xenopus oocytes: demonstration of light-dependent ionic currents.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(21):7917-21.
1988: Braiman M S; Mogi T; Marti T; Stern L J; Khorana H G; Rothschild K J
Vibrational spectroscopy of bacteriorhodopsin mutants: light-driven proton transport involves protonation changes of aspartic acid residues 85, 96, and 212.
Biochemistry 1988;27(23):8516-20.
1988: Ahl P L; Stern L J; Düring D; Mogi T; Khorana H G; Rothschild K J
Effects of amino acid substitutions in the F helix of bacteriorhodopsin. Low temperature ultraviolet/visible difference spectroscopy.
The Journal of biological chemistry 1988;263(27):13594-601.
1988: Sakmar T P; Khorana H G
Total synthesis and expression of a gene for the alpha-subunit of bovine rod outer segment guanine nucleotide-binding protein (transducin).
Nucleic acids research 1988;16(14A):6361-72.
1988: Mogi T; Stern L J; Marti T; Chao B H; Khorana H G
Aspartic acid substitutions affect proton translocation by bacteriorhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(12):4148-52.
1988: Khorana H G
Bacteriorhodopsin, a membrane protein that uses light to translocate protons.
The Journal of biological chemistry 1988;263(16):7439-42.
1988: Franke R R; Sakmar T P; Oprian D D; Khorana H G
A single amino acid substitution in rhodopsin (lysine 248----leucine) prevents activation of transducin.
The Journal of biological chemistry 1988;263(5):2119-22.
1988: Braiman M; Bubis J; Doi T; Chen H B; Flitsch S L; Franke R R; Gilles-Gonzalez M A; Graham R M; Karnik S S; Khorana H G
Studies on light transduction by bacteriorhodopsin and rhodopsin.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 1():355-64.
1988: Braiman M S; Mogi T; Stern L J; Hackett N R; Chao B H; Khorana H G; Rothschild K J
Vibrational spectroscopy of bacteriorhodopsin mutants: I. Tyrosine-185 protonates and deprotonates during the photocycle.
Proteins 1988;3(4):219-29.
1987: Oprian D D; Molday R S; Kaufman R J; Khorana H G
Expression of a synthetic bovine rhodopsin gene in monkey kidney cells.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(24):8874-8.
1987: Born W; Freeman M; Bornstein W; Rapoport A; Klein R D; Hendy G N; Khorana H G; Rich A; Potts J T; Kronenberg H M
Signal sequence of human preproparathyroid hormone is inactive in yeast.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1987;2(4):353-60.
1987: Mogi T; Stern L J; Hackett N R; Khorana H G
Bacteriorhodopsin mutants containing single tyrosine to phenylalanine substitutions are all active in proton translocation.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(16):5595-9.
1987: Hackett N R; Stern L J; Chao B H; Kronis K A; Khorana H G
Structure-function studies on bacteriorhodopsin. V. Effects of amino acid substitutions in the putative helix F.
The Journal of biological chemistry 1987;262(19):9277-84.
1987: Braiman M S; Stern L J; Chao B H; Khorana H G
Structure-function studies on bacteriorhodopsin. IV. Purification and renaturation of bacterio-opsin polypeptide expressed in Escherichia coli.
The Journal of biological chemistry 1987;262(19):9271-6.
1987: Karnik S S; Nassal M; Doi T; Jay E; Sgaramella V; Khorana H G
Structure-function studies on bacteriorhodopsin. II. Improved expression of the bacterio-opsin gene in Escherichia coli.
The Journal of biological chemistry 1987;262(19):9255-63.
1987: Dunn R J; Hackett N R; McCoy J M; Chao B H; Kimura K; Khorana H G
Structure-function studies on bacteriorhodopsin. I. Expression of the bacterio-opsin gene in Escherichia coli.
The Journal of biological chemistry 1987;262(19):9246-54.
1987: Nassal M; Mogi T; Karnik S S; Khorana H G
Structure-function studies on bacteriorhodopsin. III. Total synthesis of a gene for bacterio-opsin and its expression in Escherichia coli.
The Journal of biological chemistry 1987;262(19):9264-70.
1987: Khorana H G
Recent work on bacteriorhodopsin.
Society of General Physiologists series 1987;41():1-17.
1986: Abercrombie D M; Khorana H G
Regeneration of native bacteriorhodopsin structure following acetylation of epsilon-amino groups of Lys-30, -40, and -41.
The Journal of biological chemistry 1986;261(11):4875-80.
1986: Ferretti L; Karnik S S; Khorana H G; Nassal M; Oprian D D
Total synthesis of a gene for bovine rhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(3):599-603.
1986: Khorana H G
Rhodopsin, the visual pigment, and bacteriorhodopsin.
Annals of the New York Academy of Sciences 1986;471():272-88.
1986: Gilles-Gonzalez M A; Hackett N R; Jones S J; Khorana H G; Lee D S; Lo K M; McCoy J M
Methods for mutagenesis of the bacterioopsin gene.
Methods in enzymology 1986;125():190-214.
1985: Yatsunami K; Khorana H G
GTPase of bovine rod outer segments: the amino acid sequence of the alpha subunit as derived from the cDNA sequence.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(13):4316-20.
1985: Burnett B K; Robson R J; Takagaki Y; Radhakrishnan R; Khorana H G
Synthesis of phospholipids containing photoactivatable carbene precursors in the headgroups and their crosslinking with membrane proteins.
Biochimica et biophysica acta 1985;815(1):57-67.
1985: Burnett B K; Khorana H G
A rapid and efficient procedure for the purification of mitochondrial beta-hydroxybutyrate dehydrogenase.
Biochimica et biophysica acta 1985;815(1):51-6.
1985: Yatsunami K; Pandya B V; Oprian D D; Khorana H G
cDNA-derived amino acid sequence of the gamma subunit of GTPase from bovine rod outer segments.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(7):1936-40.
1984: Liao M J; Huang K S; Khorana H G
Regeneration of native bacteriorhodopsin structure from fragments.
The Journal of biological chemistry 1984;259(7):4200-4.
1984: Liao M J; Khorana H G
Removal of the carboxyl-terminal peptide does not affect refolding or function of bacteriorhodopsin as a light-dependent proton pump.
The Journal of biological chemistry 1984;259(7):4194-9.
1984: Seehra J S; Khorana H G
Bacteriorhodopsin precursor. Characterization and its integration into the purple membrane.
The Journal of biological chemistry 1984;259(7):4187-93.
1983: Liao M J; London E; Khorana H G
Regeneration of the native bacteriorhodopsin structure from two chymotryptic fragments.
The Journal of biological chemistry 1983;258(16):9949-55.
1983: Takagaki Y; Radhakrishnan R; Wirtz K W; Khorana H G
The membrane-embedded segment of cytochrome b5 as studied by cross-linking with photoactivatable phospholipids. II. The nontransferable form.
The Journal of biological chemistry 1983;258(15):9136-42.
1983: Takagaki Y; Radhakrishnan R; Gupta C M; Khorana H G
The membrane-embedded segment of cytochrome b5 as studied by cross-linking with photoactivatable phospholipids.
The Journal of biological chemistry 1983;258(15):9128-35.
1983: McCoy J M; Khorana H G
Introduction and characterization of amber mutations in the bacteriorhodopsin gene.
The Journal of biological chemistry 1983;258(13):8456-61.
1983: Westerman J; Wirtz K W; Berkhout T; van Deenen L L; Radhakrishnan R; Khorana H G
Identification of the lipid-binding site of phosphatidylcholine-transfer protein with phosphatidylcholine analogs containing photoactivable carbene precursors.
European journal of biochemistry / FEBS 1983;132(2):441-9.
1983: DasSarma S; RajBhandary U L; Khorana H G
High-frequency spontaneous mutation in the bacterio-opsin gene in Halobacterium halobium is mediated by transposable elements.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(8):2201-5.
1983: Dunn R J; Hackett N R; Huang K S; Jones S; Khorana H G; Lee D S; Liao M J; Lo K M; McCoy J; Noguchi S
Studies on the light-transducing pigment bacteriorhodopsin.
Cold Spring Harbor symposia on quantitative biology 1983;48 Pt 2():853-62.
1982: Simsek M; DasSarma S; RajBhandary U L; Khorana H G
A transposable element from Halobacterium halobium which inactivates the bacteriorhodopsin gene.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(23):7268-72.
1982: Huang K S; Radhakrishnan R; Bayley H; Khorana H G
Orientation of retinal in bacteriorhodopsin as studied by cross-linking using a photosensitive analog of retinal.
The Journal of biological chemistry 1982;257(22):13616-23.
1982: Verret C R; Rosner M R; Khorana H G
Fatty acyl amidases from Dictyostelium discoideum that act on lipopolysaccharide and derivatives. II. Aspects of substrate specificity.
The Journal of biological chemistry 1982;257(17):10228-34.
1982: Verret C R; Rosner M R; Khorana H G
Fatty acyl amidases from Dictyostelium discoideum that act on lipopolysaccharide and derivatives. I. Partial purification and properties.
The Journal of biological chemistry 1982;257(17):10222-7.
1982: Rothschild K J; Argade P V; Earnest T N; Huang K S; London E; Liao M J; Bayley H; Khorana H G; Herzfeld J
The site of attachment of retinal in bacteriorhodopsin. A resonance Raman study.
The Journal of biological chemistry 1982;257(15):8592-5.
1982: Huang K S; Liao M J; Gupta C M; Royal N; Biemann K; Khorana H G
The site of attachment of retinal in bacteriorhodopsin. The epsilon-amino group in Lys-41 is not required for proton translocation.
The Journal of biological chemistry 1982;257(15):8596-9.
1982: London E; Khorana H G
Denaturation and renaturation of bacteriorhodopsin in detergents and lipid-detergent mixtures.
The Journal of biological chemistry 1982;257(12):7003-11.
1982: Ross A H; Radhakrishnan R; Robson R J; Khorana H G
The transmembrane domain of glycophorin A as studied by cross-linking using photoactivatable phospholipids.
The Journal of biological chemistry 1982;257(8):4152-61.
1982: Kimura K; Mason T L; Khorana H G
Immunological probes for bacteriorhodopsin. Identification of three distinct antigenic sites on the cytoplasmic surface.
The Journal of biological chemistry 1982;257(6):2859-67.
1982: Höjeberg B; Lind C; Khorana H G
Reconstitution of bacteriorhodopsin vesicles with Halobacterium halobium lipids. Effects of variations in lipid composition.
The Journal of biological chemistry 1982;257(4):1690-4.
1981: Dunn R; McCoy J; Simsek M; Majumdar A; Chang S H; Rajbhandary U L; Khorana H G
The bacteriorhodopsin gene.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(11):6744-8.
1981: Lind C; Höjeberg B; Khorana H G
Reconstitution of delipidated bacteriorhodopsin with endogenous polar lipids.
The Journal of biological chemistry 1981;256(16):8298-305.
1981: Chang S H; Majumdar A; Dunn R; Makabe O; RajBhandary U L; Khorana H G; Ohtsuka E; Tanaka T; Taniyama Y O; Ikehara M
Bacteriorhodopsin: partial sequence of mRNA provides amino acid sequence in the precursor region.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(6):3398-402.
1981: Dunn R J; Belagaje R; Brown E L; Khorana H G
The synthesis and cloning of two tyrosine suppressor tRNA genes with altered promoter sequences.
The Journal of biological chemistry 1981;256(12):6109-18.
1981: Quay S C; Radhakrishnan R; Khorana H G
Incorporation of photosensitive fatty acids into phospholipids of Escherichia coli and irradiation-dependent cross-linking of phospholipids to membrane proteins.
The Journal of biological chemistry 1981;256(9):4444-9.
1981: Huang K S; Bayley H; Liao M J; London E; Khorana H G
Refolding of an integral membrane protein. Denaturation, renaturation, and reconstitution of intact bacteriorhodopsin and two proteolytic fragments.
The Journal of biological chemistry 1981;256(8):3802-9.
1981: Bayley H; Radhakrishnan R; Huang K S; Khorana H G
Light-driven proton translocation by bacteriorhodopsin reconstituted with the phenyl analog of retinal.
The Journal of biological chemistry 1981;256(8):3797-801.
1981: Bayley H; Huang K S; Radhakrishnan R; Ross A H; Takagaki Y; Khorana H G
Site of attachment of retinal in bacteriorhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(4):2225-9.
1981: Curatolo W; Radhakrishnan R; Gupta C M; Khorana H G
Photoactivatable carbene-generating phospholipids: physical properties and use in detection of phase separations in lipid mixtures.
Biochemistry 1981;20(5):1374-8.
1981: Gerber G E; Radhakrishhnan R; Gupta C M; Khorana H G
Interaction of cholesterol with photoactivable phospholipids in sonicated vesicles.
Biochimica et biophysica acta 1981;640(3):646-54.
1981: Radhakrishnan R; Robson R J; Takagaki Y; Khorana H G
An alternative method of preparing radiolabeled photoactivatable fatty acids.
Methods in enzymology 1981;72():793-4.
1981: Radhakrishnan R; Robson R J; Takagaki Y; Khorana H G
Synthesis of modified fatty acids and glycerophospholipid analogs.
Methods in enzymology 1981;72():408-33.
1980: Takagaki Y; Gupta C M; Khorana H G
Thiols and the diazo group in photoaffinity labels.
Biochemical and biophysical research communications 1980;95(2):589-95.
1980: Takagaki Y; Gerber G E; Nihei K; Khorana H G
Amino acid sequence of the membranous segment of rabbit liver cytochrome b5. Methodology for separation of hydrophobic peptides.
The Journal of biological chemistry 1980;255(4):1536-41.
1980: Huang K S; Bayley H; Khorana H G
Delipidation of bacteriorhodopsin and reconstitution with exogenous phospholipid.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(1):323-7.
1980: Wirtz K W; Moonen P; van Deenen L L; Radhakrishnan R; Khorana H G
Identification of the lipid binding site of the phosphatidylcholine exchange protein with a photosensitive nitrene and carbene precursor of phosphatidylcholine.
Annals of the New York Academy of Sciences 1980;348():244-55.
1980: Radhakrishnan R; Gupta C M; Erni B; Robson R J; Curatolo W; Majumdar A; Ross A H; Takagaki Y; Khorana H G
Phospholipids containing photoactivable groups in studies of biological membranes.
Annals of the New York Academy of Sciences 1980;346():165-98.
1979: Ryan M J; Belagaje R; Brown E L; Fritz H J; Khorana H G
A synthetic tyrosine suppressor tRNA gene with an altered promoter sequence. Its cloning and relative expression in vivo.
The Journal of biological chemistry 1979;254(21):10803-10.
1979: Khorana H G; Gerber G E; Herlihy W C; Gray C P; Anderegg R J; Nihei K; Biemann K
Amino acid sequence of bacteriorhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(10):5046-50.
1979: Rosner M R; Verret R C; Khorana H G
The structure of lipopolysaccharide from an Escherichia coli heptose-less mutant. III. Two fatty acyl amidases from Dictyostelium discoideum and their action on lipopolysaccharide derivatives.
The Journal of biological chemistry 1979;254(13):5926-33.
1979: Rosner M R; Khorana H G; Satterthwait A C
The structure of lipopolysaccharide from a heptose-less mutant of Escherichia coli K-12. II. The application of 31P NMR spectroscopy.
The Journal of biological chemistry 1979;254(13):5818-25.
1979: Ryan M J; Brown E L; Sekiya T; Küpper H; Khorana H G
Total synthesis of a tyrosine suppressor tRNA gene. XVIII. Biological activity and transcription, in vitro, of the cloned gene.
The Journal of biological chemistry 1979;254(13):5817-26.
1979: Sekiya T; Brown E L; Belagaje R; Fritz H J; Gait M J; Lees R G; Ryan M J; Khorana H G; Norris K E
Total synthesis of a tyrosine suppressor tRNA gene. XV. Synthesis of the promoter region.
The Journal of biological chemistry 1979;254(13):5781-6.
1979: Belagaje R; Brown E L; Fritz H J; Lees R G; Khorana H G
Total synthesis of a tyrosine suppressor transfer RNA gene. XIV. Chemical synthesis of oligonucleotide segments corresponding to the terminal regions.
The Journal of biological chemistry 1979;254(13):5765-80.
1979: Rosner M R; Tang J; Barzilay I; Khorana H G
Structure of the lipopolysaccharide from an Escherichia coli heptose-less mutant. I. Chemical degradations and identification of products.
The Journal of biological chemistry 1979;254(13):5906-17.
1979: Sekiya T; Takeya T; Brown E L; Belagaje R; Contreras R; Fritz H J; Gait M J; Lees R G; Ryan M J; Khorana H G; Norris K E
Total synthesis of a tyrosine suppressor transfer RNA gene. XVI. Enzymatic joinings to form the total 207-base pair-long DNA.
The Journal of biological chemistry 1979;254(13):5787-801.
1979: Belagaje R; Brown E L; Gait M J; Khorana H G; Norris K E
Total synthesis of a tyrosine suppressor transfer RNA gene. XIII. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence -1 to -29 in the promoter region.
The Journal of biological chemistry 1979;254(13):5754-63.
1979: Sekiya T; Contreras R; Takeya T; Khorana H G
Total synthesis of a tyrosine suppressor transfer RNA gene. XVII. Transcription, in vitro, of the synthetic gene and processing of the primary transcript to transfer RNA.
The Journal of biological chemistry 1979;254(13):5802-16.
1979: Gupta C M; Radhakrishnan R; Gerber G E; Olsen W L; Quay S C; Khorana H G
Intermolecular crosslinking of fatty acyl chains in phospholipids: use of photoactivable carbene precursors.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(6):2595-9.
1979: Olsen W L; Schaechter M; Khorana H G
Incorporation of synthetic fatty acid analogs into phospholipids of Escherichia coli.
Journal of bacteriology 1979;137(3):1443-6.
1979: Khorana H G
Total synthesis of a gene.
Science (New York, N.Y.) 1979;203(4381):614-25.
1979: Gerber G E; Anderegg R J; Herlihy W C; Gray C P; Biemann K; Khorana H G
Partial primary structure of bacteriorhodopsin: sequencing methods for membrane proteins.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(1):227-31.
1979: Brown E L; Belagaje R; Ryan M J; Khorana H G
Chemical synthesis and cloning of a tyrosine tRNA gene.
Methods in enzymology 1979;68():109-51.
1978: Jones R A; Fritz H J; Khorana H G
Use of the lipophilic tert-butyldiphenylsilyl protecting group in synthesis and rapid separation of polynucleotides.
Biochemistry 1978;17(7):1268-78.
1978: Fritz H J; Belagaje R; Brown E L; Fritz R H; Jones R A; Lees R G; Khorana H G
High-pressure liquid chromatography in polynucleotide synthesis.
Biochemistry 1978;17(7):1257-67.
1977: Gerber G E; Gray C P; Wildenauer D; Khorana H G
Orientation of bacteriorhodopsin in Halobacterium halobium as studied by selective proteolysis.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(12):5426-30.
1977: Gupta C M; Radhakrishnan R; Khorana H G
Glycerophospholipid synthesis: improved general method and new analogs containing photoactivable groups.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(10):4315-9.
1977: Wildenauer D; Khorana H G
The preparation of lipid-depleted bacteriorhodopsin.
Biochimica et biophysica acta 1977;466(2):315-24.
1976: Contreras R; Küpper H; Landy A; Khorana H G
Escherichia coli tyrosine transfer ribonucleic acid genes. Nucleotide sequences of their promoters and of the regions adjoining C-C-A ends.
The Journal of biological chemistry 1976;251(17):5124-40.
1976: Sekiya T; Gait M J; Noris K; Ramamoorthy B; Khorana H G
The nucleotide sequence in the promoter region of the gene for an Escherichia coli tyrosine transfer ribonucleic acid.
The Journal of biological chemistry 1976;251(15):4481-9.
1976: Agarwal K L; Berlin Y A; Fritz H J; Gait M J; Kleid D G; Lees R G; Norris K E; Ramamoorthy B; Khorana H G
Studies on polynucleotides. CXLIII. A rapid and convenient method for the synthesis of deoxyribooligonucleotides carrying 5'-phosphate end groups using a new protecting group.
Journal of the American Chemical Society 1976;98(5):1065-72.
1976: Panet A; Kleppe R; Kleppe K; Khorana H G
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 9. Enzymatic joining of chemically synthesized deoxyribopolynucleotide segments corresponding to nucleotide sequence 57-94.
The Journal of biological chemistry 1976;251(3):651-7.
1976: Loewen P C; Miller R C; Panet A; Sekiya T; Khorana H G
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 8. Enzymatic joining of the chemically synthesized segments to form DNA duplexes corresponding to nucleotide sequences 23-60 and 23-66.
The Journal of biological chemistry 1976;251(3):642-59.
1976: Sekiya T; Besmer P; Takeya T; Khorana H G
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 7. Enzymatic joining of the chemically synthesized segments to form a DNA duplex corresponding to the nucleotide sequence 1-26.
The Journal of biological chemistry 1976;251(3):634-41.
1976: Agarwal K L; Caruthers M H; Büchi H; van de Sande J H; Khorana H G
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 6. Synthesis of the deoxyribopolynucleotide segments corresponding to the nucleotide sequence 100-126.
The Journal of biological chemistry 1976;251(3):624-33.
1976: Jay E; Cashion P J; Fridkin M; Ramamoorthy B; Agarwal K L; Caruthers M H; Khorana H G
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 5. Synthesis of the deoxyribopolynucleotide segments representing the nucleotide sequence 71-103.
The Journal of biological chemistry 1976;251(3):609-23.
1976: Agarwal K L; Caruthers M H; Fridkin M; Kumar A; van de Sande J H; Khorana H G
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 4. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence 47-78.
The Journal of biological chemistry 1976;251(3):599-608.
1976: van de Sande J H; Caruthers M H; Kumar A; Khorana H G
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 2. Chemical synthesis of the deoxypolynucleotide segments corresponding to the nucleotide sequence 1-31.
The Journal of biological chemistry 1976;251(3):571-86.
1976: Khorana H G; Agarwal K L; Besmer P; Büchi H; Caruthers M H; Cashion P J; Fridkin M; Jay E; Kleppe K; Kleppe R; Kumar A; Loewen P C; Miller R C; Minamoto K; Panet A; RajBhandary U L; Ramamoorthy B; Sekiya T; Takeya T; van de Sande J H
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 1. General introduction.
The Journal of biological chemistry 1976;251(3):565-70.
1976: Ramamoorthy B; Lees R C; Kleid D G; Khorana H G
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 12. Synthesis of a DNA duplex corresponding to a sequence of 23 nucleotide units adjoining the C-C-A end.
The Journal of biological chemistry 1976;251(3):676-94.
1976: Kleppe R; Sekiya T; Loewen P C; Kleppe K; Agarwal K L; Büchi H; Besmer P; Caruthers M H; Cashion P J; Fridkin M; Jay E; Kumar A; Miller R C; Minamoto K; Panet A; RajBhandary U L; Ramamoorthy B; Sidorova N; Takeya T; van de Sande J H; Khorana H G
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 11. Enzymatic joining to form the total DNA duplex.
The Journal of biological chemistry 1976;251(3):667-75.
1976: Caruthers M H; Kleppe R; Kleppe K; Khorana H G
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 10. Enzymatic joining of chemically synthesized segments to form the DNA duplex corresponding to the nucleotide sequence 86-126.
The Journal of biological chemistry 1976;251(3):658-66.
1976: Minamoto K; Caruthers M H; Ramamoorthy B; van de Sande J H; Sidorova N; Khorana H G
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 3. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence 27-51.
The Journal of biological chemistry 1976;251(3):587-98.
1976: Contreras R; Khorana H G
Proceedings: Controlled transcription of the synthetic gene for tyrosine transfer RNA.
Archives internationales de physiologie et de biochimie 1976;84(1):145-7.
1976: Greenberg G R; Chakrabarti P; Khorana H G
Incorporation of fatty acids containing photosensitive groups into phospholipids of Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(1):86-90.
1975: Küpper H; Contreras R; Landy A; Khorana H G
Promoter-dependent transcription of tRNAITyr genes using DNA fragments produced by restriction enzymes.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(12):4754-8.
1975: Agarwal K L; Berlin Y A; Kleid D G; Smirnov V D; Khorana H G
The synthesis of a DNA duplex corresponding to the icosanucleotide sequence at the 5' end of messenger RNA from the gene N of bacteriophage lambda.
The Journal of biological chemistry 1975;250(14):5563-73.
1975: Kleid D G; Agarwal K L; Khorana H G
The nucleotide sequence in the promoter region of the gene N in bacteriophage lambda.
The Journal of biological chemistry 1975;250(14):5574-82.
1975: Knowles A F; Kandrach A; Racker E; Khorana H G
Acetyl phosphatidylethanolamine in the reconstitution of ion pumps.
The Journal of biological chemistry 1975;250(5):1809-13.
1975: Powers G J; Jones R L; Randall G A; Caruthers M H; van de Sande J H; Khorana H G
Optimal strategies for the chemical and enzymatic synthesis of bihelical deoxyribonucleic acids.
Journal of the American Chemical Society 1975;97(4):875-84.
1975: Sekiua T; Ormondt H V; Khorana H G
The nucleotide sequence in the promoter region of the fene for an Escherichia coli tyrosine transfer ribonucleic acid.
The Journal of biological chemistry 1975;250(3):1087-98.
1974: Sekiya T; Khorana H G
Nucleotide sequence in the promoter region of the Escherichia coli tyrosine tRNA gene.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(8):2978-82.
1974: Panet A; Khorana H G
Studies on polynucleotides. The linkage of deoxyribopolynucleotide templates to cellulose and its use in their replication.
The Journal of biological chemistry 1974;249(16):5213-21.
1974: Loewen P C; Sekiya T; Khorana H G
The nucleotide sequence adjoining the CCA end of an Escherichia coli tyrosine transfer ribonucleic acid gene.
The Journal of biological chemistry 1974;249(1):217-26.
1974: Fridkin M; Cashion P J; Agarwal K L; Jay E; Khorana H G
Rapid separation of synthetic oligonucleotide mixtures on aromatic cellulose derivatives.
Methods in enzymology 1974;34():645-9.
1973: van de Sande J H; Kleppe K; Khorana H G
Reversal of bacteriophage T4 induced polynucleotide kinase action.
Biochemistry 1973;12(25):5050-5.
1973: Panet A; van de Sande J H; Loewen P C; Khorana H G; Raae A J; Lillehaug J R; Kleppe K
Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase.
Biochemistry 1973;12(25):5045-50.
1973: Cashion P J; Fridkin M; Agarwal K L; Jay E; Khorana H G
Use of trityl- and -naphthylcarbamoylcellulose derivatives in oligonucleotide synthesis.
Biochemistry 1973;12(10):1985-90.
1973: Loewen P C; Khorana H G
Studies on polynucleotides. CXXII. The dodecanucleotide sequence adjoining the C-C-A end of the tyrosine transfer ribonucleic acid gene.
The Journal of biological chemistry 1973;248(10):3489-99.
1973: Agarwal K L; Fridkin M; Jay E; Khorana H G
Deoxyoligonucleotide synthesis using a new phosphate protecting group.
Journal of the American Chemical Society 1973;95(6):2020-1.
1972: Besmer P; Miller R C; Caruthers M H; Kumar A; Minamoto K; Van de Sande J H; Sidarova N; Khorana H G
Studies on polynucleotides. CXVII. Hybridization of polydeoxynucleotides with tyrosine transfer RNA sequences to the r-strand of phi80psu + 3 DNA.
Journal of molecular biology 1972;72(3):503-22.
1972: Caruthers M H; Kleppe K; Van de Sande J H; Sgaramella V; Agarwal K L; Büchi H; Gupta N K; Kumar A; Otsuka E; RajBhandary U L; Terao T; Weber H; Yamada T; Khorana H G
CXV. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining to form the total DNA duplex.
Journal of molecular biology 1972;72(2):475-92.
1972: Van de Sande J H; Caruthers M H; Sgaramella V; Yamada T; Khorana H G
CXIV. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized segments to form the DNA duplex corresponding to nucleotide sequence 46 to 77.
Journal of molecular biology 1972;72(2):457-74.
1972: Sgaramella V; Kleppe K; Terao T; Gupta N K; Khorana H G
113. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized segments to form the DNA duplex corresponding to nucleotide sequence 17 to 50.
Journal of molecular biology 1972;72(2):445-56.
1972: Sgaramella V; Khorana H G
CXII. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized polydeoxynucleotides to form the DNA duplex representing nucleotide sequence 1 to 20.
Journal of molecular biology 1972;72(2):427-44.
1972: Caruthers M H; Khorana H G
CXI. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of a dodecadeoxynucleotide and a heptadeoxynucleotide corresponding to the nucleotide sequence 66 to 77.
Journal of molecular biology 1972;72(2):407-26.
1972: Caruthers M H; Van de Sande J H; Khorana H G
CX. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of three decadeoxynucleotides corresponding to the nucleotide sequence 51 to 70.
Journal of molecular biology 1972;72(2):375-405.
1972: Agarwal K L; Kumar A; Khorana H G
CIX. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of a dodecadeoxynucleotide and a decadeoxynucleotide corresponding to the nucleotide sequence 46 to 65.
Journal of molecular biology 1972;72(2):351-73.
1972: Kumar A; Khorana H G
108. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of an undecadeoxynucleotide, a decadeoxynucleotide and an octadeoxynucleotide corresponding to the nucleotide sequences 7 to 27.
Journal of molecular biology 1972;72(2):329-49.
1972: Otsuka E; Kumar A; Khorana H G
CVII. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of a dodecadeoxynucleotide and a hexadeoxynucleotide corresponding to the nucleotide sequence 1 to 12.
Journal of molecular biology 1972;72(2):309-27.
1972: Kumar A; Otsuka E; Khorana H G
CVI. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of two nonanucleotides and a heptanucleotide corresponding to nucleotide sequences 22 to 30, 41 to 49 and 28 to 34.
Journal of molecular biology 1972;72(2):289-307.
1972: Büchi H; Khorana H G
CV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxyribonucleotide corresponding to the nucleotide sequence 31 to 50.
Journal of molecular biology 1972;72(2):251-88.
1972: Weber H; Khorana H G
CIV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxynucleotide corresponding to the nucleotide sequence 21 to 40.
Journal of molecular biology 1972;72(2):219-49.
1972: Khorana H G; Agarwal K L; Büchi H; Caruthers M H; Gupta N K; Kleppe K; Kumar A; Otsuka E; RajBhandary U L; Van de Sande J H; Sgaramella V; Terao T; Weber H; Yamada T
Studies on polynucleotides. 103. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast.
Journal of molecular biology 1972;72(2):209-17.
1972: Sogaramella V; Khorana H G
Studies on polynucleotides. CXVI. A further study of the T4 ligase-catalyzed joining of DNA at base-paired ends.
Journal of molecular biology 1972;72(3):493-502.
1972: Terao T; Dahlberg J E; Khorana H G
Studies on polynucleotides. CXX. On the transcription of a synthetic 29-unit long deoxyribopolynucleotide.
The Journal of biological chemistry 1972;247(19):6157-66.
1972: Kleppe R; Khorana H G
Studies on polynucleotides. CXIX. Transcription of short double-stranded deoxyribonucleic acids of defined nucleotide sequences.
The Journal of biological chemistry 1972;247(19):6149-56.
1972: Van de Sande J H; Loewen P C; Khorana H G
Studies on polynucleotides. 118. A further study of ribonucleotide incorporation into deoxyribonucleic acid chains by deoxyribonucleic acid polymerase I of Escherichia coli.
The Journal of biological chemistry 1972;247(19):6140-8.
1972: Agarwal K L; Yamazaki A; Cashion P J; Khorana H G
Chemical synthesis of polynucleotides.
Angewandte Chemie (International ed. in English) 1972;11(6):451-9.
1972: Agarwal K L; Khorana H G
Studies on polynucleotides. CII. The use of aromatic isocyanates for selective blocking of the terminal 3'-hydroxyl group in protected deoxyribooligonucleotides.
Journal of the American Chemical Society 1972;94(10):3578-85.
1972: Gefter M L; Molineux I J; Kornberg T; Khorana H G
Deoxyribonucleic acid synthesis in cell-free extracts. 3. Catalytic properties of deoxyribonucleic acid polymerase II.
The Journal of biological chemistry 1972;247(10):3321-6.
1971: Agarwal K L; Yamazaki A; Khorana H G
Studies on polynucleotides. 98. A convenient and general method for the preparation of protected dideoxyribonucleotides containing 5'-phosphate end groups.
Journal of the American Chemical Society 1971;93(11):2754-62.
1971: Paetkau V H; Khorana H G
Preparation of a circular bihelical deoxyribonucleic acid containing repeating dinucleotide sequences.
Biochemistry 1971;10(9):1511-21.
1971: Miller R C; Besmer P; Khorana H G; Fiandt M; Szybalski W
Studies on polynucleotides. XCVII. Opposing orientations and location of the su+3 gene in the transducing coliphages phi-80psu+3 and phi-80dsu+3su-3.
Journal of molecular biology 1971;56(2):363-8.
1971: Kleppe K; Ohtsuka E; Kleppe R; Molineux I; Khorana H G
Studies on polynucleotides. XCVI. Repair replications of short synthetic DNA's as catalyzed by DNA polymerases.
Journal of molecular biology 1971;56(2):341-61.
1970: Sgaramella V; Van de Sande J H; Khorana H G
Studies on polynucleotides, C. A novel joining reaction catalyzed by the T4-polynucleotide ligase.
Proceedings of the National Academy of Sciences of the United States of America 1970;67(3):1468-75.
1970: Kleppe K; Van de Sande J H; Khorana H G
Polynucleotide ligase-catalyzed joining of deoxyribo-oligonucleotides on ribopolynucleotide templates and of ribo-oligonucleotides on deoxyribopolynucleotide templates.
Proceedings of the National Academy of Sciences of the United States of America 1970;67(1):68-73.
1970: Agarwal K L; Büchi H; Caruthers M H; Gupta N; Khorana H G; Kleppe K; Kumar A; Ohtsuka E; Rajbhandary U L; Van de Sande J H; Sgaramella V; Weber H; Yamada T
Total synthesis of the gene for an alanine transfer ribonucleic acid from yeast.
Nature 1970;227(5253):27-34.
1969: Hachmann J; Khorana H G
Studies on polynucleotides. 93. A further study of the synthesis of deoxyribopolynucleotides using preformed oligonucleotide blocks.
Journal of the American Chemical Society 1969;91(10):2749-57.
1969: Kumar A; Khorana H G
Studies of polynucleotides. XCII. The synthesis of a deoxyribododecanucleotide containing specific amino acid codons.
Journal of the American Chemical Society 1969;91(10):2743-9.
1968: Khorana H G
Synthetic nucleic acids and the genetic code.
JAMA : the journal of the American Medical Association 1968;206(9):1978-82.
1968: Khorana H G
Synthesis in the study of nucleic acids. The Fourth Jubilee Lecture.
The Biochemical journal 1968;109(5):709-25.
1968: Gupta N K; Khorana H G
Studies on polynucleotides, XC. DNA polymerase-catalyzed repair of short DNA duplexes with single-stranded ends.
Proceedings of the National Academy of Sciences of the United States of America 1968;61(1):215-22.
1968: Gupta N K; Ohtsuka E; Sgaramella V; Buchi H; Kumar A; Weber H; Khorana H G
Studies on polynucleotides, 88. Enzymatic joining of chemically synthesized segments corresponding to the gene for alanine-tRNA.
Proceedings of the National Academy of Sciences of the United States of America 1968;60(4):1338-44.
1968: Gupta N K; Ohtsuka E; Weber H; Chang S H; Khorana H G
Studies on polynucleotides. LXXXVII. The joining of short deoxyribopolynucleotides by DNA-joining enzymes.
Proceedings of the National Academy of Sciences of the United States of America 1968;60(1):285-92.
1968: RajBhandary U L; Stuart A; Hoskinson R M; Khorana H G
Studies on polynucleotides. 78. Yeast phenylalanine transfer ribonucleic acid: terminal sequences.
The Journal of biological chemistry 1968;243(3):565-74.
1968: Khorana H G; Büchi H; Caruthers M H; Chang S H; Gupta N K; Kumar A; Ohtsuka E; Sgaramella V; Weber H
Progress in the total synthesis of the gene for ala-tRNA.
Cold Spring Harbor symposia on quantitative biology 1968;33():35-44.
1967: Ghosh H P; Khorana H G
Studies on polynucleotides, LXXXIV. On the role of ribosomal subunits in protein synthesis.
Proceedings of the National Academy of Sciences of the United States of America 1967;58(6):2455-61.
1967: Hayatsu H; Khorana H G
Studies on polynucleotides. LXXII. Deoxyribooligonucleotide synthesis on a polymer support.
Journal of the American Chemical Society 1967;89(15):3880-7.
1967: Wells R D; Büchi H; Kössel H; Ohtsuka E; Khorana H G
Studies on polynucleotides. LXX. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: DNA-like polymers containing repeating tetranucleotide sequences.
Journal of molecular biology 1967;27(2):265-72.
1967: Wells R D; Jacob T M; Narang S A; Khorana H G
Studies on polynucleotides. LXIX. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: DNA-like polymers containing repeating trinucleotide sequences.
Journal of molecular biology 1967;27(2):237-63.
1967: Morgan A R; Wells R D; Khorana H G
Studies on polynucleotides. LXXIV. Direct translation in vitro of single-stranded DNA-like polymers with repeating nucleotide sequences in the presence of neomycin B.
Journal of molecular biology 1967;26(3):477-97.
1967: Kössel H; Morgan A R; Khorana H G
Studies on polynucleotides. 73. Synthesis in vitro of polypeptides containing repeating tetrapeptide sequences dependent upon DNA-like polymers containing repeating tetranucleotide sequences: direction of reading of messenger RNA.
Journal of molecular biology 1967;26(3):449-75.
1967: Ghosh H P; Söll D; Khorana H G
Studies on polynucleotides. LXVII. Initiation of protein synthesis in vitro as studied by using ribopolynucleotides with repeating nucleotide sequences as messengers.
Journal of molecular biology 1967;25(2):275-98.
1966: Söll D; Jones D S; Ohtsuka E; Faulkner R D; Lohrmann R; Hayatsu H; Khorana H G
Specificity of sRNA for recognition of codons as studied by the ribosomal binding technique.
Journal of molecular biology 1966;19(2):556-73.
1966: Gupta N K; Khorana H G
Missense suppression of the tryptophan synthetase A-protein mutant A78.
Proceedings of the National Academy of Sciences of the United States of America 1966;56(2):772-9.
1966: Davies J; Jones D S; Khorana H G
A further study of misreading of codons induced by streptomycin and neomycin using ribopolynucleotides containing two nucleotides in alternating sequence as templates.
Journal of molecular biology 1966;18(1):48-57.
1966: Moon M W; Khorana H G
Studies on polynucleotides. LV. The use of mesitoyl chloride in the synthesis of internucleotide bonds.
Journal of the American Chemical Society 1966;88(8):1805-9.
1966: Jones D S; Nishimura S; Khorana H G
Studies on polynucleotides. LVI. Further syntheses, in vitro of copolypeptides containing two amino acids in alternating sequence dependent upon DNA-like polymers containing two nucleotides in alternating sequence.
Journal of molecular biology 1966;16(2):454-72.
1966: Moon M W; Khorana H G
Studies on polynucleotides. LIV. A further study of the reaction of nucleotide pyrophosphates with carboxylic acid anhydrides.
Journal of the American Chemical Society 1966;88(8):1798-804.
1966: Moon M W; Nishimura S; Khorana H G
Studies on polynucleotides. 53. Syntheses of trinucleotides containing adenylate and 2'-deoxyadenylate units and a study of their effect on the binding of lysyl soluble ribonucleic acid to ribosomes.
Biochemistry 1966;5(3):937-45.
1966: Lohrmann R; Söll D; Hayatsu H; Ohtsuka E; Khorana H G
Studies on polynucleotides. LI. Syntheses of the 64 possible ribotrinucleotides derived from the four major ribomononucleotides.
Journal of the American Chemical Society 1966;88(4):819-29.
1966: Khorana H G; Büchi H; Ghosh H; Gupta N; Jacob T M; Kössel H; Morgan R; Narang S A; Ohtsuka E; Wells R D
Polynucleotide synthesis and the genetic code.
Cold Spring Harbor symposia on quantitative biology 1966;31():39-49.
1966: RajBhandary U L; Stuart A; Faulkner R D; Chang S H; Khorana H G
Nucleotide sequence studies on yeast phenylalanine sRNA.
Cold Spring Harbor symposia on quantitative biology 1966;31():425-34.
1966: Khorana H G
Polynucleotide synthesis and the genetic code.
Harvey lectures 1966;62():79-105.
1966: Söll D; Cherayil J; Jones D S; Faulkner R D; Hapel A; Bock R M; Khorana H G
sRNA specificity for codon recognition as studied by the ribosomal binding technique.
Cold Spring Harbor symposia on quantitative biology 1966;31():51-61.
1966: Gupta N K; RajBhandary U L; Khorana H G
Missense suppression in tryptophan synthetase.
Cold Spring Harbor symposia on quantitative biology 1966;31():499-500.
1965: Wells R D; Ohtsuka E; Khorana H G
Studies on polynucleotides. L. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: a new double-stranded DNA-like polymer containing repeating dinucleotide sequences.
Journal of molecular biology 1965;14(1):221-37.
1965: Söll D; Ohtsuka E; Jones D S; Lohrmann R; Hayatsu H; Nishimura S; Khorana H G
Studies on polynucleotides, XLIX. Stimulation of the binding of aminoacyl-sRNA's to ribosomes by ribotrinucleotides and a survey of codon assignments for 20 amino acids.
Proceedings of the National Academy of Sciences of the United States of America 1965;54(5):1378-85.
1965: Khorana H G
Polynucleotide synthesis and the genetic code.
Federation proceedings 1965;24(6):1473-87.
1965: Jackson J F; Kornberg R D; Berg P; Rajbhandary U L; Stuart A; Khorana H G; Kornberg A
On the heterogeneity of the deoxyribonucleic acid associated with crystalline yeast cytochrome b2.
Biochimica et biophysica acta 1965;108(2):243-8.
1965: Nishimura S; Jones D S; Khorana H G
Studies on polynucleotides. 48. The in vitro synthesis of a co-polypeptide containing two amino acids in alternating sequence dependent upon a DNA-like polymer containing two nucleotides in alternating sequence.
Journal of molecular biology 1965;13(1):302-24.
1965: JACOB T M; KHORANA H G
STUDIES ON POLYNUCLEOTIDES. XLIV. THE SYNTHESIS OF DODECANUCLEOTIDES CONTAINING THE REPEATING TRINUCLEOTIDE SEQUENCE THYMIDYLYL-(3'--5')-THYMIDYLYL-(3'--5')-DEOXYCYTIDINE.
Journal of the American Chemical Society 1965;87():2971-81.
1965: NARANG S A; JACOB T M; KHORANA H G
STUDIES ON POLYNUCLEOTIDES. XLVI. THE SYNTHESIS OF HEXANUCLEOTIDES CONTAINING THE REPEATING TRINUCLEOTIDE SEQUENCES DEOXYCYCTIDYLYL-(3'--5')-DEOXYADENYLYL-(3'--5')-DEOXYADENOSINE AND DEOXYGUANYLYL-(3'--5')-DEOXYADENYLYL-(3'--5')-DEOXYADENOSINE.
Journal of the American Chemical Society 1965;87():2988-95.
1965: NARANG S A; KHORANA H G
STUDIES ON POLYNUCLEOTIDES. XLV. THE SYNTHESIS OF DODECANUCLEOTIDES CONTAINING THE REPEATING TRINUCLEOTIDE SEQUENCE THYMIDYLYL-(3'--5')-THYMIDYLYL-(3'--5')-DEOXYINOSINE.
Journal of the American Chemical Society 1965;87():2981-8.
1965: OHTSUKA E; MOON M W; KHORANA H G
STUDIES ON POLYNUCLEOTIDES. 43. THE SYNTHESIS OF DEOXRIBOPOLYNUCLEOTIDES CONTAINING REPEATING DINUCLEOTIDE SEQUENCES.
Journal of the American Chemical Society 1965;87():2956-70.
1965: KHORANA H G; JACOB T M; MOON M W; NARANG S A; OHTSUKA E
STUDIES ON POLYNUCLEOTIDES.XLII. THE SYNTHESIS OF DEOXYRIBOPOLYNUCLEOTIDES CONTAINING REPEATING NUCLEOTIDE SEQUENCES. INTRODUCTION AND GENERAL CONSIDERATIONS.
Journal of the American Chemical Society 1965;87():2954-6.
1965: HOSKINSON R M; KHORANA H G
STUDIES ON POLYNUCLEOTIDES. XLI. PURIFICATION OF PHENYLALANINE-SPECIFIC TRANSFER RIBONUCLEIC ACID FROM YEAST BY COUNTERCURRENT DISTRIBUTION.
The Journal of biological chemistry 1965;240():2129-34.
1965: MEHROTRA B D; KHORANA H G
STUDIES ON POLYNUCLEOTIDES. XL. SYNTHETIC DEOXYRIBOPOLYNUCLEOTIDES AS TEMPLATES FOR RIBONUCLEIC ACID POLYMERASE: THE INFLUENCE OF TEMPERATURE ON TEMPLATE FUNCTION.
The Journal of biological chemistry 1965;240():1750-3.
1965: BYRD C; OHTSUKA E; MOON M W; KHORANA H G
SYNTHETIC DEOXYRIBO-OLIGONUCLEOTIDES AS TEMPLATES FOR THE DNA POLYMERASE OF ESCHERICHIA COLI: NEW DNA-LIKE L-POLYMERS CONTAINING REPEATING NUCLEOTIDE SEQUENCES.
Proceedings of the National Academy of Sciences of the United States of America 1965;53():79-86.
1965: JACOB T M; KHORANA H G
STUDIES ON POLYNUCLEOTIDES. XXXVII. THE SYNTHESIS OF SPECIFIC DEOXYRIBOPOLYNUCLEOTIDES. FURTHER EXAMINATION OF THE APPROACH INVOLVING STEPWISE SYNTHESIS.
Journal of the American Chemical Society 1965;87():368-74.
1965: SOELL D; KHORANA H G
STUDIES ON POLYNUCLEOTIDES. XXXVI. THE SPECIFIC SYNTHESIS OF C3'-C5'-LINKED RIBOOLIGONUCLEOTIDES. IX. THE SYNTHESIS OF RIBODINUCLEOTIDES BEARING 3'-PHOSPHOMONOESTER GROUPS.
Journal of the American Chemical Society 1965;87():360-7.
1965: SOELL D; KHORANA H G
STUDIES ON POLYNUCLEOTIDES. XXXV. THE SPECIFIC SYNTHESIS OF C3'-C5'-LINKED RIBOOLIGONUCLEOTIDES. 8. THE SYNTHESIS OF RIBODINUCLEOTIDES BEARING 3'-PHOSPHOMONOESTER GROUPS.
Journal of the American Chemical Society 1965;87():350-9.
1964: NISHIMURA S; JACOB T M; KHORANA H G
SYNTHETIC DEOXYRIBOPOLYNUCLEOTIDES AS TEMPLATES FOR RIBONUCLEIC ACID POLYMERASE: THE FORMATION AND CHARACTERIZATION OF A RIBOPOLYNUCLEOTIDE WITH A REPEATING TRINUCLEOTIDE SEQUENCE.
Proceedings of the National Academy of Sciences of the United States of America 1964;52():1494-501.
1964: STUART A; KHORANA H G
STUDIES ON POLYNUCLEOTIDES. 33. THE LABELING OF END GROUPS IN POLYNUCLEOTIDE CHAINS: THE SELECTIVE ACETYLATION OF TERMINAL HYDROXYL GROUPS IN DEOXYRIBOPOLYNUCLEOTIDES.
The Journal of biological chemistry 1964;239():3885-92.
1964: RAJBHANDARY U L; YOUNG R J; KHORANA H G
STUDIES ON POLYNUCLEOTIDES. XXXII. THE LABELING OF END GROUPS IN POLYNUCLEOTIDE CHAINS: THE SELECTIVE PHOSPHORYLATION OF PHOSPHOMONOESTER GROUPS IN AMINO ACID ACCEPTOR RIBONUCLEIC ACIDS.
The Journal of biological chemistry 1964;239():3875-84.
1964: KORNBERG A; BERTSCH L L; JACKSON J F; KHORANA H G
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID, XVI. OLIGONUCLEOTIDES AS TEMPLATES AND THE MECHANISM OF THEIR REPLICATION.
Proceedings of the National Academy of Sciences of the United States of America 1964;51():315-23.
1963: FALASCHI A; ADLER J; KHORANA H G
CHEMICALLY SYNTHESIZED DEOXYPOLYNUCLEOTIDES AS TEMPLATES FOR RIBONUCLEIC ACID POLYMERASE.
The Journal of biological chemistry 1963;238():3080-5.
1963: FIERS W; KHORANA H G
STUDIES ON POLYNUCLEOTIDES. 23. ENZYMIC DEGRADATION. AN EXONUCLEASE FROM LACTOBACILLUS ACIDOPHILUS R26. B. STEPWISE DEGRADATION OF OLIGONUCLEOTIDES.
The Journal of biological chemistry 1963;238():2789-96.
1963: FIERS W; KHORANA H G
STUDIES ON POLYNUCLEOTIDES. XXII. ENZYMIC DEGRADATION. AN EXONUCLEASE FROM LACTOBACILLUS ACIDOPHILUS R26. A. PURIFICATION, PROPERTIES, AND SUBSTRATE SPECIFICITY.
The Journal of biological chemistry 1963;238():2780-8.
1963: FIERS W; KHORANA H G
[The purification and the characterization of an exonuclease of Lactobacillus acidophilus R 26.]
Archives internationales de physiologie et de biochimie 1963;71():299-301.
1962: RAMMLER D H; KHORANA H G
The specific synthesis of C3,-C5,-linked uridine oligonucleotides.
Biochemical and biophysical research communications 1962;8():61-5.
1962: RAMMLER D H; KHORANA H G
A new approach to the specific synthesis of the C3'-C5' inter-ribonucleotide linkage.
Biochemical and biophysical research communications 1962;7():147-50.
1962: RALPH R K; SMITH R A; KHORANA H G
Studies on polynucleotides. XV. Enzymic degradation. The mode of action of pancreatic deoxyribonuclease on thymidine, deoxycytidine, and deoxyadenosine polynucleotides.
Biochemistry 1962;1():131-7.
1961: RAZZELL W E; KHORANA H G
Studies on polynucleotides. X. Enzymic degradation. Some properties and mode of action of spleen phosphodiesterase.
The Journal of biological chemistry 1961;236():1144-9.
1960: KHORANA H G
Synthesis of nucleotides, nucleotide coenzymes and polynucleotides.
Federation proceedings 1960;19():931-41.
1959: KHORANA H G
Synthesis and structural analysis of polynucleotides.
Journal of cellular and comparative physiology 1959;54():5-15.
1959: TENER G M; GILHAM P T; RAZZELL W E; TURNER A F; KHORANA H G
Studies on the chemical synthesis and enzymatic degradation of desoxyribo-oligonucleotides.
Annals of the New York Academy of Sciences 1959;81():757-75.
1959: RAZZELL W E; KHORANA H G
Studies on polynucleotides. IV. Enzymic degradation; the stepwise action of venom phosphodiesterase on deoxyribo-oligonucleotides.
The Journal of biological chemistry 1959;234(8):2114-7.
1959: RAZZELL W E; KHORANA H G
Studies on polynucleotides. III. Enzymic degradation; substrate specificity and properties of snake venom phosphodiesterase.
The Journal of biological chemistry 1959;234(8):2105-13.
1959: SHUSTER L; KHORANA H G; HEPPEL L A
The mode of action of ryegrass ribonuclease.
Biochimica et biophysica acta 1959;33(2):452-61.
1958: RAZZELL W E; KHORANA H G
Purification and properties of a pyrimidine deoxyriboside phosphorylase from Escherichia coli.
Biochimica et biophysica acta 1958;28(3):562-6.
1958: KHORANA H G; FERNANDES J F; KORNBERG A
Pyrophosphorylation of ribose 5-phosphate in the enzymatic synthesis of 5-phosphorylribose 1-pyrophosphate.
The Journal of biological chemistry 1958;230(2):941-8.

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