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Hippokratis Kiaris

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Nikolina Dioufa; Elena Farmaki; Ioulia Chatzistamou; Athanasios G Papavassiliou; Hippokratis Kiaris
p53 antagonizes the unfolded protein response and inhibits ground glass hepatocyte development during endoplasmic reticulum stress.
Elena Farmaki; Panagiotis Bourlis; Ioulia Chatzistamou; Athanasios G Papavassiliou; Eleni Santoukou; Georgios Trimis; Hippokratis Kiaris
Selection of p53-Deficient Stromal Cells in the Tumor Microenvironment.
Donald C Porter; Anatoliy T Puzyrev; Rebecca Rokow-Kittell; Gary P Schools; Jun Shi; Mark P Wentland; Deborah K West; Serena Altilia; Phil S Baran; Eugenia Broude; Bey-Dih Chang; Mengqian Chen; Elena Farmaki; Lawrence T Friedhoff; Balazs Gyorffy; Gregory Hurteau; Swathi Kalurupalle; Hippokratis Kiaris; Chang-uk Lim; Athanasios G Papavassiliou; Igor B Roninson
Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.

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All Publications

2012: Nikolina Dioufa; Elena Farmaki; Ioulia Chatzistamou; Athanasios G Papavassiliou; Hippokratis Kiaris
p53 antagonizes the unfolded protein response and inhibits ground glass hepatocyte development during endoplasmic reticulum stress.
Experimental biology and medicine (Maywood, N.J.) 2012;237(10):1173-80.
2012: Elena Farmaki; Panagiotis Bourlis; Ioulia Chatzistamou; Athanasios G Papavassiliou; Eleni Santoukou; Georgios Trimis; Hippokratis Kiaris
Selection of p53-Deficient Stromal Cells in the Tumor Microenvironment.
Genes & cancer 2012;3(9-10):592-8.
2012: Donald C Porter; Anatoliy T Puzyrev; Rebecca Rokow-Kittell; Gary P Schools; Jun Shi; Mark P Wentland; Deborah K West; Serena Altilia; Phil S Baran; Eugenia Broude; Bey-Dih Chang; Mengqian Chen; Elena Farmaki; Lawrence T Friedhoff; Balazs Gyorffy; Gregory Hurteau; Swathi Kalurupalle; Hippokratis Kiaris; Chang-uk Lim; Athanasios G Papavassiliou; Igor B Roninson
Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(34):13799-804.
2012: Nikolina Dioufa; Elena Farmaki; Hippokratis Kiaris; Christos Kittas; Athanasios G Papavassiliou; Andrew V Schally; Dimitris Vlahodimitropoulos; Norman Block; Ioulia Chatzistamou
Growth hormone-releasing hormone receptor splice variant 1 is frequently expressed in oral squamous cell carcinomas.
Hormones & cancer 2012;3(4):172-80.
2011: Petros D Grivas; Hippokratis Kiaris; Athanasios G Papavassiliou
Tackling transcription factors: challenges in antitumor therapy.
Trends in molecular medicine 2011;17(10):537-8.
2011: Ioulia Chatzistamou; Nikolina Dioufa; Hippokratis Kiaris; Christos Kittas; AD Sklavounou; George Trimis; Athanasios G Papavassiliou
p21/waf1 and smooth-muscle actin α expression in stromal fibroblasts of oral cancers.
Cellular oncology (Dordrecht) 2011;34(5):483-8.
2011: E Farmaki; S Mkrtchian; I Papazian; Athanasios G Papavassiliou; Hippokratis Kiaris
ERp29 regulates response to doxorubicin by a PERK-mediated mechanism.
Biochimica et biophysica acta 2011;1813(6):1165-71.
2011: Eleni Meliou; Nikolaos Kerezoudis; Konstantinos I Tosios; Daniel Lafkas; Hippokratis Kiaris
Immunohistochemical expression of Notch signaling in the lining epithelium of periapical cysts.
Journal of endodontics 2011;37(2):176-80.
2011: Hippokratis Kiaris; Norman Block; Athanasios G Papavassiliou; Andrew V Schally
GHRH and wound healing.
Communicative & integrative biology 2011;4(1):82-3.
2010: Nikolina Dioufa; Andrew V Schally; Ioulia Chatzistamou; Evi Moustou; Norman Block; Gary K Owens; Athanasios G Papavassiliou; Hippokratis Kiaris
Acceleration of wound healing by growth hormone-releasing hormone and its agonists.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(43):18611-5.
2010: N Dioufa; Eva Kassi; Athanasios G Papavassiliou; Hippokratis Kiaris
Atypical induction of the unfolded protein response by mifepristone.
Endocrine 2010;38(2):167-73.
2010: Stamatia Tzanopoulou; Marina Sagnou; Maria Paravatou-Petsotas; Eleni Gourni; George Loudos; Stavros Xanthopoulos; Daniel Lafkas; Hippokratis Kiaris; Alexandra Varvarigou; Ioannis Pirmettis; Minas Papadopoulos; Maria Pelecanou
Evaluation of Re and (99m)Tc complexes of 2-(4'-aminophenyl)benzothiazole as potential breast cancer radiopharmaceuticals.
Journal of medicinal chemistry 2010;53(12):4633-41.
2010: Hippokratis Kiaris
Editorial.
Seminars in cell & developmental biology 2010;21(1):1.
2010: E Meliou; Np Kerezoudis; Konstantinos I Tosios; Hippokratis Kiaris
Notch 1 Receptor, Delta 1 Ligand and HES 1 Transcription Factor are Expressed in the Lining Epithelium of Periapical Cysts (Preliminary Study).
The open dentistry journal 2010;4():153-8.
2010: Ioulia Chatzistamou; Nikolina Dioufa; George Trimis; AD Sklavounou; Christos Kittas; Hippokratis Kiaris; Athanasios G Papavassiliou
p21/waf1 and smooth-muscle actin α expression in stromal fibroblasts of oral cancers.
Analytical cellular pathology (Amsterdam) 2010;33(1):19-26.
2010: Chrysovalantou Mihailidou; Irene Papazian; Athanasios G Papavassiliou; Hippokratis Kiaris
CHOP-dependent regulation of p21/waf1 during ER stress.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2010;25(6):761-6.
2008: George Trimis; Ioulia Chatzistamou; Katerina Politi; Hippokratis Kiaris; Athanasios G Papavassiliou
Expression of p21waf1/Cip1 in stromal fibroblasts of primary breast tumors.
Human molecular genetics 2008;17(22):3596-600.
2008: Aspasia-Athina Volakaki; Daniel Lafkas; Eva Kassi; Andrew V Schally; Athanasios G Papavassiliou; Hippokratis Kiaris
Essential role of p21/waf1 in the mediation of the anti-proliferative effects of GHRH antagonist JMR-132.
Journal of molecular endocrinology 2008;41(5):389-92.
2008: Souren Mkrtchian; Mikhail Baryshev; Ernest Sargsyan; Ioulia Chatzistamou; Aspasia-Athina Volakaki; Nick Chaviaras; Agatha Pafiti; Aggeliki Triantafyllou; Hippokratis Kiaris
ERp29, an endoplasmic reticulum secretion factor is involved in the growth of breast tumor xenografts.
Molecular carcinogenesis 2008;47(11):886-92.
2008: Daniel Lafkas; George Trimis; Athanasios G Papavassiliou; Hippokratis Kiaris
P53 mutations in stromal fibroblasts sensitize tumors against chemotherapy.
International journal of cancer. Journal international du cancer 2008;123(4):967-71.
2008: Erasmia Tsellou; Hippokratis Kiaris
Fibroblast independency in tumors: implications in cancer therapy.
Future oncology (London, England) 2008;4(3):427-32.
2008: Ioulia Chatzistamou; Aspasia-Athina Volakaki; Andrew V Schally; Hippokratis Kiaris; Christos Kittas
Expression of growth hormone-releasing hormone receptor splice variant 1 in primary human melanomas.
Regulatory peptides 2008;147(1-3):33-6.
2007: Nektarios Barabutis; Erasmia Tsellou; Andrew V Schally; Stavroula Kouloheri; Anastasios Kalofoutis; Hippokratis Kiaris
Stimulation of proliferation of MCF-7 breast cancer cells by a transfected splice variant of growth hormone-releasing hormone receptor.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(13):5575-9.
2006: Christos Cheretis; Frank Dietrich; Ioulia Chatzistamou; Katerina Politi; Eirini Angelidou; Hippokratis Kiaris; Souren Mkrtchian; Helen Koutselini
Expression of ERp29, an endoplasmic reticulum secretion factor in basal-cell carcinoma.
The American Journal of dermatopathology 2006;28(5):410-2.
2006: C Christodoulou; Andrew V Schally; Ioulia Chatzistamou; Agatha Kondi-Pafiti; Klea Lamnissou; S Kouloheri; Anastasios Kalofoutis; Hippokratis Kiaris
Expression of growth hormone-releasing hormone (GHRH) and splice variant of GHRH receptors in normal mouse tissues.
Regulatory peptides 2006;136(1-3):105-8.
2006: Hippokratis Kiaris
Anatomically independent tumors revisited.
Future oncology (London, England) 2006;2(4):463-7.
2006: Apostolos Klinakis; Matthias Szabolcs; Katerina Politi; Hippokratis Kiaris; Spyros Artavanis-Tsakonas; Argiris Efstratiadis
Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9262-7.
2006: Hippokratis Kiaris
GHRH analogs and cancer.
Combinatorial chemistry & high throughput screening 2006;9(3):161.
2005: Hippokratis Kiaris; Ioulia Chatzistamou; George Trimis; Matrisa Frangou-Plemmenou; Agatha Pafiti-Kondi; Anastasios Kalofoutis
Evidence for nonautonomous effect of p53 tumor suppressor in carcinogenesis.
Cancer research 2005;65(5):1627-30.
2005: Eva Kassi; Panayiotis G Vlachoyiannopoulos; Antonios Kominakis; Hippokratis Kiaris; Haralampos M Moutsopoulos; paraskevi moutsatsou
Estrogen receptor alpha gene polymorphism and systemic lupus erythematosus: a possible risk?
Lupus 2005;14(5):391-8.
2005: Hippokratis Kiaris; Andrew V Schally; Anastasios Kalofoutis
Extrapituitary effects of the growth hormone-releasing hormone.
Vitamins and hormones 2005;70():1-24.
2004: Ioulia Chatzistamou; Andrew V Schally; Hippokratis Kiaris; Ekaterini Politi; Jozsef Varga; George Kanellis; Anastasios Kalofoutis; Agathi Pafiti; Helen Koutselini
Immunohistochemical detection of GHRH and its receptor splice variant 1 in primary human breast cancers.
European journal of endocrinology / European Federation of Endocrine Societies 2004;151(3):391-6.
2004: Hippokratis Kiaris; Katerina Politi; Lisa M Grimm; Matthias Szabolcs; Peter Fisher; Argiris Efstratiadis; Spyros Artavanis-Tsakonas
Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium.
The American journal of pathology 2004;165(2):695-705.
2004: Hippokratis Kiaris; Ioulia Chatzistamou; Ch Kalofoutis; Helen Koutselini; Christina Piperi; Anastasios Kalofoutis
Tumour-stroma interactions in carcinogenesis: basic aspects and perspectives.
Molecular and cellular biochemistry 2004;261(1-2):117-22.
2003: Hippokratis Kiaris; Ioulia Chatzistamou; Andrew V Schally; Gabor Halmos; Jozsef Varga; Helen Koutselini; Anastasios Kalofoutis
Ligand-dependent and -independent effects of splice variant 1 of growth hormone-releasing hormone receptor.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(16):9512-7.
2003: Hippokratis Kiaris; Michael Koutsilieris; Anastasios Kalofoutis; Andrew V Schally
Growth hormone-releasing hormone and extra-pituitary tumorigenesis: therapeutic and diagnostic applications of growth hormone-releasing hormone antagonists.
Expert opinion on investigational drugs 2003;12(8):1385-94.
2002: Ioulia Chatzistamou; Andrew V Schally; Agathi Pafiti; Hippokratis Kiaris; Helen Koutselini
Expression of growth hormone-releasing hormone in human primary endometrial carcinomas.
European journal of endocrinology / European Federation of Endocrine Societies 2002;147(3):381-6.
2002: Karoly Szepeshazi; Andrew V Schally; Gabor Halmos; Patricia Armatis; Francine Hebert; Baodong Sun; Anita Feil; Hippokratis Kiaris; Attila Nagy
Targeted cytotoxic somatostatin analogue AN-238 inhibits somatostatin receptor-positive experimental colon cancers independently of their p53 status.
Cancer research 2002;62(3):781-8.
2002: Hippokratis Kiaris; Andrew V Schally; Rebeca Busto; Gabor Halmos; Spyros Artavanis-Tsakonas; Jozsef Varga
Expression of a splice variant of the receptor for GHRH in 3T3 fibroblasts activates cell proliferation responses to GHRH analogs.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):196-200.
2001: Hippokratis Kiaris; Andrew V Schally; Attila Nagy; Karoly Szepeshazi; Francine Hebert; Gabor Halmos
A targeted cytotoxic somatostatin (SST) analogue, AN-238, inhibits the growth of H-69 small-cell lung carcinoma (SCLC) and H-157 non-SCLC in nude mice.
European journal of cancer (Oxford, England : 1990) 2001;37(5):620-8.
2001: Hippokratis Kiaris; Andrew V Schally; Patricia Armatis
Direct action of growth hormone-releasing hormone agonist JI-38 on normal human fibroblasts: evidence from studies on cell proliferation and c-myc proto-oncogene expression.
Regulatory peptides 2001;96(3):119-24.
2001: Jose M Arencibia; Andrew V Schally; Gabor Halmos; Attila Nagy; Hippokratis Kiaris
In vitro targeting of a cytotoxic analog of luteinizing hormone-releasing hormone AN-207 to ES-2 human ovarian cancer cells as demonstrated by microsatellite analyses.
Anti-cancer drugs 2001;12(1):71-8.
2000: Hippokratis Kiaris; Andrew V Schally; Jozsef Varga
Suppression of tumor growth by growth hormone-releasing hormone antagonist JV-1-36 does not involve the inhibition of autocrine production of insulin-like growth factor II in H-69 small cell lung carcinoma.
Cancer letters 2000;161(2):149-55.
2000: Artur Plonowski; Andrew V Schally; Attila Nagy; Hippokratis Kiaris; Francine Hebert; Gabor Halmos
Inhibition of metastatic renal cell carcinomas expressing somatostatin receptors by a targeted cytotoxic analogue of somatostatin AN-238.
Cancer research 2000;60(11):2996-3001.
2000: Hippokratis Kiaris; Andrew V Schally; Jozsef Varga
Antagonists of growth hormone-releasing hormone inhibit the growth of U-87MG human glioblastoma in nude mice.
Neoplasia (New York, N.Y.) 2000;2(3):242-50.
2000: Hippokratis Kiaris; Andrew V Schally; Attila Nagy; Baodong Sun; Karoly Szepeshazi; Gabor Halmos
Regression of U-87 MG human glioblastomas in nude mice after treatment with a cytotoxic somatostatin analog AN-238.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(2):709-17.
1999: Hippokratis Kiaris; Andrew V Schally; Jozsef Varga; Kate Groot; Patricia Armatis
Growth hormone-releasing hormone: an autocrine growth factor for small cell lung carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):14894-8.
1999: Hippokratis Kiaris; Andrew V Schally; Baodong Sun; Patricia Armatis; Kate Groot
Inhibition of growth of human malignant glioblastoma in nude mice by antagonists of bombesin/gastrin-releasing peptide.
Oncogene 1999;18(50):7168-73.
1999: Hippokratis Kiaris; Andrew V Schally; Attila Nagy; Baodong Sun; Patricia Armatis; Karoly Szepeshazi
Targeted cytotoxic analogue of bombesin/gastrin-releasing peptide inhibits the growth of H-69 human small-cell lung carcinoma in nude mice.
British journal of cancer 1999;81(6):966-71.
1999: Hippokratis Kiaris; Andrew V Schally
Apoptosis versus necrosis: which should be the aim of cancer therapy?
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1999;221(2):87-8.
1999: VJ Csernus; Andrew V Schally; Hippokratis Kiaris; Patricia Armatis
Inhibition of growth, production of insulin-like growth factor-II (IGF-II), and expression of IGF-II mRNA of human cancer cell lines by antagonistic analogs of growth hormone-releasing hormone in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3098-103.
1999: Hippokratis Kiaris; Andrew V Schally
Decrease in telomerase activity in U-87MG human glioblastomas after treatment with an antagonist of growth hormone-releasing hormone.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(1):226-31.