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Jan Kiel

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Aksam Eda Bener; de Vries Bart; van der Klei Ida J; Kiel Jan A K W
Preserving organelle vitality: peroxisomal quality control mechanisms in yeast.
Kiel Jan A K W; van den Berg Marco A; Fusetti Fabrizia; Poolman Bert; Bovenberg Roel A L; Veenhuis Marten; van der Klei Ida J
Matching the proteome to the genome: the microbody of penicillin-producing Penicillium chrysogenum cells.
Kiel Jan A K W; van der Klei Ida J
Proteins involved in microbody biogenesis and degradation in Aspergillus nidulans.

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2009: Aksam Eda Bener; de Vries Bart; van der Klei Ida J; Kiel Jan A K W
Preserving organelle vitality: peroxisomal quality control mechanisms in yeast.
FEMS yeast research 2009;9(6):808-20.
2009: Kiel Jan A K W; van den Berg Marco A; Fusetti Fabrizia; Poolman Bert; Bovenberg Roel A L; Veenhuis Marten; van der Klei Ida J
Matching the proteome to the genome: the microbody of penicillin-producing Penicillium chrysogenum cells.
Functional & integrative genomics 2009;9(2):167-84.
2009: Kiel Jan A K W; van der Klei Ida J
Proteins involved in microbody biogenesis and degradation in Aspergillus nidulans.
Fungal genetics and biology : FG & B 2009;46 Suppl 1():S62-71.
2008: van den Berg Marco A; Albang Richard; Albermann Kaj; Badger Jonathan H; Daran Jean-Marc; Driessen Arnold J M; Garcia-Estrada Carlos; Fedorova Natalie D; Harris Diana M; Heijne Wilbert H M; Joardar Vinita; Kiel Jan A K W; Kovalchuk Andriy; Martín Juan F; Nierman William C; Nijland Jeroen G; Pronk Jack T; Roubos Johannes A; van der Klei Ida J; van Peij Noël N M E; Veenhuis Marten; von Döhren Hans; Wagner Christian; Wortman Jennifer; Bovenberg Roel A L
Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum.
Nature biotechnology 2008;26(10):1161-8.
2008: Nagotu Shirisha; Krikken Arjen M; Otzen Marleen; Kiel Jan A K W; Veenhuis Marten; van der Klei Ida J
Peroxisome fission in Hansenula polymorpha requires Mdv1 and Fis1, two proteins also involved in mitochondrial fission.
Traffic (Copenhagen, Denmark) 2008;9(9):1471-84.
2008: van Zutphen Tim; van der Klei Ida J; Kiel Jan A K W
Pexophagy in Hansenula polymorpha.
Methods in enzymology 2008;451():197-215.
2008: Gidijala Loknath; Bovenberg Roel A L; Klaassen Paul; van der Klei Ida J; Veenhuis Marten; Kiel Jan A K W
Production of functionally active Penicillium chrysogenum isopenicillin N synthase in the yeast Hansenula polymorpha.
BMC biotechnology 2008;8():29.
2007: de Vries Bart; Kiel Jan A K W; Scheek Ruud; Veenhuis Marten; van der Klei Ida J
A conserved alpha helical domain at the N-terminus of Pex14p is required for PTS1 and PTS2 protein import in Hansenula polymorpha.
FEBS letters 2007;581(29):5627-34.
2007: Kiel Jan A K W; Titorenko Vladimir I; van der Klei Ida J; Veenhuis Marten
Overproduction of translation elongation factor 1-alpha (eEF1A) suppresses the peroxisome biogenesis defect in a Hansenula polymorpha pex3 mutant via translational read-through.
FEMS yeast research 2007;7(7):1114-25.
2007: Gidijala Loknath; van der Klei Ida J; Veenhuis Marten; Kiel Jan A K W
Reprogramming Hansenula polymorpha for penicillin production: expression of the Penicillium chrysogenum pcl gene.
FEMS yeast research 2007;7(7):1160-7.
2007: Meijer Wiebe H; van der Klei Ida J; Veenhuis Marten; Kiel Jan A K W
ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes.
Autophagy 2007;3(2):106-16.
2007: Aksam Eda Bener; Koek Anne; Kiel Jan A K W; Jourdan Stefanie; Veenhuis Marten; van der Klei Ida J
A peroxisomal lon protease and peroxisome degradation by autophagy play key roles in vitality of Hansenula polymorpha cells.
Autophagy 2007;3(2):96-105.
2007: Kiel Jan A K W; Otzen Marleen
The 4th Hansenula polymorpha Worldwide Network Conference, Haren (The Netherlands), 3-5 September 2006.
FEMS yeast research 2007;7(1):167-71.
2006: Sakai Yasuyoshi; Oku Masahide; van der Klei Ida J; Kiel Jan A K W
Pexophagy: autophagic degradation of peroxisomes.
Biochimica et biophysica acta 2006;1763(12):1767-75.
2006: Kiel Jan A K W; Veenhuis Marten; van der Klei Ida J
PEX genes in fungal genomes: common, rare or redundant.
Traffic (Copenhagen, Denmark) 2006;7(10):1291-303.
2005: Stevens Patricia; Monastyrska Iryna; Leão-Helder Adriana N; van der Klei Ida J; Veenhuis Marten; Kiel Jan A K W
Hansenula polymorpha Vam7p is required for macropexophagy.
FEMS yeast research 2005;5(11):985-97.
2005: Kiel Jan A K W; Otzen Marleen; Veenhuis Marten; van der Klei Ida J
Obstruction of polyubiquitination affects PTS1 peroxisomal matrix protein import.
Biochimica et biophysica acta 2005;1745(2):176-86.
2005: Monastyrska Iryna; Kiel Jan A K W; Krikken Arjen M; Komduur Janet A; Veenhuis Marten; van der Klei Ida J
The Hansenula polymorpha ATG25 gene encodes a novel coiled-coil protein that is required for macropexophagy.
Autophagy 2005;1(2):92-100.
2005: Dunn William A; Cregg James M; Kiel Jan A K W; van der Klei Ida J; Oku Masahide; Sakai Yasuyoshi; Sibirny Andrei A; Stasyk Oleh V; Veenhuis Marten
Pexophagy: the selective autophagy of peroxisomes.
Autophagy 2005;1(2):75-83.
2005: Kiel Jan A K W; van der Klei Ida J; van den Berg Marco A; Bovenberg Roel A L; Veenhuis Marten
Overproduction of a single protein, Pc-Pex11p, results in 2-fold enhanced penicillin production by Penicillium chrysogenum.
Fungal genetics and biology : FG & B 2005;42(2):154-64.
2005: Monastyrska Iryna; van der Heide Meis; Krikken Arjen M; Kiel Jan A K W; van der Klei Ida J; Veenhuis Marten
Atg8 is essential for macropexophagy in Hansenula polymorpha.
Traffic (Copenhagen, Denmark) 2005;6(1):66-74.
2005: Kiel Jan A K W; Emmrich Kerstin; Meyer Helmut E; Kunau Wolf-H
Ubiquitination of the peroxisomal targeting signal type 1 receptor, Pex5p, suggests the presence of a quality control mechanism during peroxisomal matrix protein import.
The Journal of biological chemistry 2005;280(3):1921-30.
2004: Leão-Helder Adriana N; Krikken Arjen M; Gellissen Gerd; van der Klei Ida J; Veenhuis Marten; Kiel Jan A K W
Atg21p is essential for macropexophagy and microautophagy in the yeast Hansenula polymorpha.
FEBS letters 2004;577(3):491-5.
2004: Leão-Helder Adriana N; Krikken Arjen M; Lunenborg Marcel G J; Kiel Jan A K W; Veenhuis Marten; van der Klei Ida J
Hansenula polymorpha Tup1p is important for peroxisome degradation.
FEMS yeast research 2004;4(8):789-94.
2004: Trip Hein; Evers Melchior E; Kiel Jan A K W; Driessen Arnold J M
Uptake of the beta-lactam precursor alpha-aminoadipic acid in Penicillium chrysogenum is mediated by the acidic and the general amino acid permease.
Applied and environmental microbiology 2004;70(8):4775-83.
2004: Kiel Jan A K W; van den Berg Marco; Bovenberg Roel A L; van der Klei Ida J; Veenhuis Marten
Penicillium chrysogenum Pex5p mediates differential sorting of PTS1 proteins to microbodies of the methylotrophic yeast Hansenula polymorpha.
Fungal genetics and biology : FG & B 2004;41(7):708-20.
2004: Monastryska Iryna; Sjollema Klaas; van der Klei Ida J; Kiel Jan A K W; Veenhuis Marten
Microautophagy and macropexophagy may occur simultaneously in Hansenula polymorpha.
FEBS letters 2004;568(1-3):135-8.
2004: Ozimek Paulina; Lahtchev Kantcho; Kiel Jan A K W; Veenhuis Marten; van der Klei Ida J
Hansenula polymorpha Swi1p and Snf2p are essential for methanol utilisation.
FEMS yeast research 2004;4(7):673-82.
2003: Leão Adriana N; Kiel Jan A K W
Peroxisome homeostasis in Hansenula polymorpha.
FEMS yeast research 2003;4(2):131-9.
2003: Leao-Helder Adriana Nívea; Krikken Arjen M; van der Klei Ida J; Kiel Jan A K W; Veenhuis Marten
Transcriptional down-regulation of peroxisome numbers affects selective peroxisome degradation in Hansenula polymorpha.
The Journal of biological chemistry 2003;278(42):40749-56.
2003: Kiel Jan A K W; Komduur Janet A; van der Klei Ida J; Veenhuis Marten
Macropexophagy in Hansenula polymorpha: facts and views.
FEBS letters 2003;549(1-3):1-6.
2003: Bellu Anna Rita; Kiel Jan A K W
Selective degradation of peroxisomes in yeasts.
Microscopy research and technique 2003;61(2):161-70.
2003: Veenhuis Marten; Kiel Jan A K W; Van Der Klei Ida J
Peroxisome assembly in yeast.
Microscopy research and technique 2003;61(2):139-50.
2003: Komduur Janet A; Veenhuis Marten; Kiel Jan A K W
The Hansenula polymorpha PDD7 gene is essential for macropexophagy and microautophagy.
FEMS yeast research 2003;3(1):27-34.
2002: Bellu Anna Rita; Salomons Florian A; Kiel Jan A K W; Veenhuis Marten; Van Der Klei Ida J
Removal of Pex3p is an important initial stage in selective peroxisome degradation in Hansenula polymorpha.
The Journal of biological chemistry 2002;277(45):42875-80.
2002: Komduur Janet A; Leão Adriana N; Monastyrska Iryna; Veenhuis Marten; Kiel Jan A K W
Old yellow enzyme confers resistance of Hansenula polymorpha towards allyl alcohol.
Current genetics 2002;41(6):401-6.
2002: Haan Gert Jan; Faber Klaas Nico; Baerends Richard J S; Koek Anne; Krikken Arjen; Kiel Jan A K W; van der Klei Ida J; Veenhuis Marten
Hansenula polymorpha Pex3p is a peripheral component of the peroxisomal membrane.
The Journal of biological chemistry 2002;277(29):26609-17.
2002: Haan Gert Jan; van Dijk Ralf; Kiel Jan A K W; Veenhuis Marten
Characterization of the Hansenula polymorpha PUR7 gene and its use as selectable marker for targeted chromosomal integration.
FEMS yeast research 2002;2(1):17-24.
2001: van Dijk R; Faber K N; Hammond A T; Glick B S; Veenhuis M; Kiel J A
Tagging Hansenula polymorpha genes by random integration of linear DNA fragments (RALF).
Molecular genetics and genomics : MGG 2001;266(4):646-56.
2001: Bellu A R; Komori M; van der Klei I J; Kiel J A; Veenhuis M
Peroxisome biogenesis and selective degradation converge at Pex14p.
The Journal of biological chemistry 2001;276(48):44570-4.
2001: Bellu A R; Kram A M; Kiel J A; Veenhuis M; van der Klei I J
Glucose-induced and nitrogen-starvation-induced peroxisome degradation are distinct processes in Hansenula polymorpha that involve both common and unique genes.
FEMS yeast research 2001;1(1):23-31.
2000: Kiel J A; Hilbrands R E; Bovenberg R A; Veenhuis M
Isolation of Penicillium chrysogenum PEX1 and PEX6 encoding AAA proteins involved in peroxisome biogenesis.
Applied microbiology and biotechnology 2000;54(2):238-42.
2000: Baerends R J; Faber K N; Kiel J A; van der Klei I J; Harder W; Veenhuis M
Sorting and function of peroxisomal membrane proteins.
FEMS microbiology reviews 2000;24(3):291-301.
2000: Salomons F A; Kiel J A; Faber K N; Veenhuis M; van der Klei I J
Overproduction of Pex5p stimulates import of alcohol oxidase and dihydroxyacetone synthase in a Hansenula polymorpha Pex14 null mutant.
The Journal of biological chemistry 2000;275(17):12603-11.
2000: Baerends R J; Faber K N; Kram A M; Kiel J A; van der Klei I J; Veenhuis M
A stretch of positively charged amino acids at the N terminus of Hansenula polymorpha Pex3p is involved in incorporation of the protein into the peroxisomal membrane.
The Journal of biological chemistry 2000;275(14):9986-95.
1999: Stasyk O V; van der Klei I J; Bellu A R; Shen S; Kiel J A; Cregg J M; Veenhuis M
A Pichia pastoris VPS15 homologue is required in selective peroxisome autophagy.
Current genetics 1999;36(5):262-9.
1999: Kiel J A; Hilbrands R E; van der Klei I J; Rasmussen S W; Salomons F A; van der Heide M; Faber K N; Cregg J M; Veenhuis M
Hansenula polymorpha Pex1p and Pex6p are peroxisome-associated AAA proteins that functionally and physically interact.
Yeast (Chichester, England) 1999;15(11):1059-78.
1999: Kiel J A; Rechinger K B; van der Klei I J; Salomons F A; Titorenko V I; Veenhuis M
The Hansenula polymorpha PDD1 gene product, essential for the selective degradation of peroxisomes, is a homologue of Saccharomyces cerevisiae Vps34p.
Yeast (Chichester, England) 1999;15(9):741-54.
1999: Will G K; Soukupova M; Hong X; Erdmann K S; Kiel J A; Dodt G; Kunau W H; Erdmann R
Identification and characterization of the human orthologue of yeast Pex14p.
Molecular and cellular biology 1999;19(3):2265-77.
1999: Vargas-Zapata R; Torres-González V; Sepúlveda-Saavedra J; Piñeyro-López A; Rechinger K B; Keizer-Gunnink I; Kiel J A; Veenhuis M
Peroxisomicine A1 (plant toxin-514) affects normal peroxisome assembly in the yeast Hansenula polymorpha.
Toxicon : official journal of the International Society on Toxinology 1999;37(2):385-98.
1999: Bellu A R; van der Klei I J; Rechinger K B; Yavuz M; Veenhuis M; Kiel J A
Characterization of the Hansenula polymorpha CPY gene encoding carboxypeptidase Y.
Yeast (Chichester, England) 1999;15(3):181-9.
1998: van der Klei I J; van der Heide M; Baerends R J; Rechinger K B; Nicolay K; Kiel J A; Veenhuis M
The Hansenula polymorpha per6 mutant is affected in two adjacent genes which encode dihydroxyacetone kinase and a novel protein, Pak1p, involved in peroxisome integrity.
Current genetics 1998;34(1):1-11.
1998: van der Klei I J; Hilbrands R E; Kiel J A; Rasmussen S W; Cregg J M; Veenhuis M
The ubiquitin-conjugating enzyme Pex4p of Hansenula polymorpha is required for efficient functioning of the PTS1 import machinery.
The EMBO journal 1998;17(13):3608-18.
1998: van der Giezen M; Kiel J A; Sjollema K A; Prins R A
The hydrogenosomal malic enzyme from the anaerobic fungus neocallimastix frontalis is targeted to mitochondria of the methylotrophic yeast hansenula polymorpha.
Current genetics 1998;33(2):131-5.
1997: Baerends R J; Salomons F A; Kiel J A; van der Klei I J; Veenhuis M
Deviant Pex3p levels affect normal peroxisome formation in Hansenula polymorpha: a sharp increase of the protein level induces the proliferation of numerous, small protein-import competent peroxisomes.
Yeast (Chichester, England) 1997;13(15):1449-63.
1997: Baerends R J; Salomons F A; Faber K N; Kiel J A; Van der Klei I J; Veenhuis M
Deviant Pex3p levels affect normal peroxisome formation in Hansenula polymorpha: high steady-state levels of the protein fully abolish matrix protein import.
Yeast (Chichester, England) 1997;13(15):1437-48.
1997: Albertini M; Rehling P; Erdmann R; Girzalsky W; Kiel J A; Veenhuis M; Kunau W H
Pex14p, a peroxisomal membrane protein binding both receptors of the two PTS-dependent import pathways.
Cell 1997;89(1):83-92.
1997: Komori M; Rasmussen S W; Kiel J A; Baerends R J; Cregg J M; van der Klei I J; Veenhuis M
The Hansenula polymorpha PEX14 gene encodes a novel peroxisomal membrane protein essential for peroxisome biogenesis.
The EMBO journal 1997;16(1):44-53.
1996: Distel B; Erdmann R; Gould S J; Blobel G; Crane D I; Cregg J M; Dodt G; Fujiki Y; Goodman J M; Just W W; Kiel J A; Kunau W H; Lazarow P B; Mannaerts G P; Moser H W; Osumi T; Rachubinski R A; Roscher A; Subramani S; Tabak H F; Tsukamoto T; Valle D; van der Klei I; van Veldhoven P P; Veenhuis M
A unified nomenclature for peroxisome biogenesis factors.
The Journal of cell biology 1996;135(1):1-3.
1996: Titorenko V I; Evers M E; Diesel A; Samyn B; Van Beeumen J; Roggenkamp R; Kiel J A; van der Klei I J; Veenhuis M
Identification and characterization of cytosolic Hansenula polymorpha proteins belonging to the Hsp70 protein family.
Yeast (Chichester, England) 1996;12(9):849-57.
1996: Baerends R J; Rasmussen S W; Hilbrands R E; van der Heide M; Faber K N; Reuvekamp P T; Kiel J A; Cregg J M; van der Klei I J; Veenhuis M
The Hansenula polymorpha PER9 gene encodes a peroxisomal membrane protein essential for peroxisome assembly and integrity.
The Journal of biological chemistry 1996;271(15):8887-94.
1996: Veenhuis M; Komori M; Salomons F; Hilbrands R E; Hut H; Baerends R J; Kiel J A; van der Klei I J
Peroxisomal remnants in peroxisome-deficient mutants of the yeast Hansenula polymorpha [corrected]
FEBS letters 1996;383(1-2):114-8.
1995: Kiel J A; Keizer-Gunnink I K; Krause T; Komori M; Veenhuis M
Heterologous complementation of peroxisome function in yeast: the Saccharomyces cerevisiae PAS3 gene restores peroxisome biogenesis in a Hansenula polymorpha per9 disruption mutant.
FEBS letters 1995;377(3):434-8.
1995: Kiel J A; ten Berge A M; Borger P; Venema G
A general method for the consecutive integration of single copies of a heterologous gene at multiple locations in the Bacillus subtilis chromosome by replacement recombination.
Applied and environmental microbiology 1995;61(12):4244-50.
1994: Kiel J A; Boels J M; Beldman G; Venema G
Glycogen in Bacillus subtilis: molecular characterization of an operon encoding enzymes involved in glycogen biosynthesis and degradation.
Molecular microbiology 1994;11(1):203-18.
1993: Kiel J A; Boels J M; Ten Berge A M; Venema G
Two putative insertion sequences flank a truncated glycogen branching enzyme gene in the thermophile Bacillus stearothermophilus CU21.
DNA sequence : the journal of DNA sequencing and mapping 1993;4(1):1-9.
1992: Kiel J A; Ten Berge A M; Venema G
Nucleotide sequence of the Synechococcus sp. PCC7942 hemE gene encoding the homologue of mammalian uroporphyrinogen decarboxylase.
DNA sequence : the journal of DNA sequencing and mapping 1992;2(6):415-8.
1992: Kiel J A; Boels J M; Beldman G; Venema G
The glgB gene from the thermophile Bacillus caldolyticus encodes a thermolabile branching enzyme.
DNA sequence : the journal of DNA sequencing and mapping 1992;3(4):221-32.
1991: Kiel J A; Boels J M; Beldman G; Venema G
Molecular cloning and nucleotide sequence of the glycogen branching enzyme gene (glgB) from Bacillus stearothermophilus and expression in Escherichia coli and Bacillus subtilis.
Molecular & general genetics : MGG 1991;230(1-2):136-44.
1990: Kiel J A; Boels J M; Beldman G; Venema G
Nucleotide sequence of the Synechococcus sp. PCC7942 branching enzyme gene (glgB): expression in Bacillus subtilis.
Gene 1990;89(1):77-84.
1989: Kiel J A; Elgersma H S; Beldman G; Vossen J P; Venema G
Cloning and expression of the branching enzyme gene (glgB) from the cyanobacterium Synechococcus sp. PCC7942 in Escherichia coli.
Gene 1989;78(1):9-17.
1987: Kiel J A; Vossen J P; Venema G
A general method for the construction of Escherichia coli mutants by homologous recombination and plasmid segregation.
Molecular & general genetics : MGG 1987;207(2-3):294-301.

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