FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Hans-Peter Kiem

Research Profile

Anatomy

Hematopoietic Stem Cells

Chemicals & Drugs

Procedures

Physiology

Living Beings

Devices

Gene Transfer Techniques

Disorders

Graft vs Host Disease

Co-author Network

Publications

TOP 3
Carolina Berger; Michael Berger; Theodore A Gooley; Hans-Peter Kiem; Brian C Beard; Stanley R Riddell
Proliferation-linked apoptosis of adoptively transferred T cells after IL-15 administration in macaques.
Jennifer E Adair; Brian C Beard; Sylvia Chien; Min Fang; Hans-Peter Kiem; Jason A Taylor; Grant Trobridge; Martin E Wohlfahrt; Xin Zhao; Pamela S Becker
Cyclophosphamide promotes engraftment of gene-modified cells in a mouse model of Fanconi anemia without causing cytogenetic abnormalities.
Jennifer L Gori; John P Kowalski; Jennifer E Adair; Brian C Beard; Devikha Chandrasekaran; Sunita L D'Souza; Hans-Peter Kiem
Efficient generation, purification, and expansion of CD34(+) hematopoietic progenitor cells from nonhuman primate-induced pluripotent stem cells.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Hans-Peter Kiem (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Carolina Berger; Michael Berger; Theodore A Gooley; Hans-Peter Kiem; Brian C Beard; Stanley R Riddell
Proliferation-linked apoptosis of adoptively transferred T cells after IL-15 administration in macaques.
PloS one 2013;8(2):e56268.
2012: Jennifer E Adair; Brian C Beard; Sylvia Chien; Min Fang; Hans-Peter Kiem; Jason A Taylor; Grant Trobridge; Martin E Wohlfahrt; Xin Zhao; Pamela S Becker
Cyclophosphamide promotes engraftment of gene-modified cells in a mouse model of Fanconi anemia without causing cytogenetic abnormalities.
Journal of molecular medicine (Berlin, Germany) 2012;90(11):1283-94.
2012: Jennifer L Gori; John P Kowalski; Jennifer E Adair; Brian C Beard; Devikha Chandrasekaran; Sunita L D'Souza; Hans-Peter Kiem
Efficient generation, purification, and expansion of CD34(+) hematopoietic progenitor cells from nonhuman primate-induced pluripotent stem cells.
Blood 2012;120(13):e35-44.
2012: Jennifer E Adair; Brian C Beard; Maciej M Mrugala; Tobias Neff; Jason K Rockhill; Daniel L Silbergeld; Grant Trobridge; Hans-Peter Kiem
Extended survival of glioblastoma patients after chemoprotective HSC gene therapy.
Science translational medicine 2012;4(133):133ra57.
2012: Korashon L Watts; Brent L Wood; Brian C Beard; R Keith Humphries; Veronica Nelson; Grant Trobridge; Hans-Peter Kiem
Hematopoietic stem cell expansion facilitates multilineage engraftment in a nonhuman primate cord blood transplantation model.
Experimental hematology 2012;40(3):187-96.
2012: Hans-Peter Kiem; Steven G Deeks; Keith R Jerome; Joseph M McCune
Hematopoietic-stem-cell-based gene therapy for HIV disease.
Cell stem cell 2012;10(2):137-47.
2012: Grant Trobridge; Robert A Wu; Brian C Beard; Christina Ironside; Punam Malik; Hans-Peter Kiem
Stem cell selection in vivo using foamy vectors cures canine pyruvate kinase deficiency.
PloS one 2012;7(9):e45173.
2012: Nina M Muñoz; David J Rawlings; Byoung Y Ryu; Andrew M Scharenberg; Grant Trobridge; Brian C Beard; Ralf M Luche; Hans-Peter Kiem
Novel reporter systems for facile evaluation of I-SceI-mediated genome editing.
Nucleic acids research 2012;40(2):e14.
2011: Bonan Zhong; Korashon L Watts; Martin E Wohlfahrt; Jennifer E Adair; Joerg Enssle; Jennifer L Gori; Hans-Peter Kiem
Safeguarding nonhuman primate iPS cells with suicide genes.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(9):1667-75.
2011: R Murnane; K Vogel; X B Zhang; R R Hukkanen; S Kelley; Hans-Peter Kiem
Myelodysplasia in 2 pig-tailed macaques (Macaca nemestrina) associated with retroviral vector-mediated insertional mutagenesis and overexpression of HOXB4.
Veterinary pathology 2011;48(5):999-1001.
2011: Yoshihiro Inamoto; Hans-Peter Kiem; Frederick R Appelbaum; Paul A Carpenter; H Joachim Deeg; Mary E D Flowers; Terry Furlong; Marco Mielcarek; Richard A Nash; Rainer F Storb; Barry E Storer; Robert P Witherspoon; Paul J Martin
A retrospective comparison of tacrolimus versus cyclosporine with methotrexate for immunosuppression after allogeneic hematopoietic cell transplantation with mobilized blood cells.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2011;17(7):1088-92.
2011: Mary E D Flowers; Yoshihiro Inamoto; Paul A Carpenter; Stephanie J Lee; Hans-Peter Kiem; Effie W Petersdorf; Shalini E Pereira; Richard A Nash; Marco Mielcarek; Matthew L Fero; Edus H Warren; Jean E Sanders; Rainer F Storb; Frederick R Appelbaum; Barry E Storer; Paul J Martin
Comparative analysis of risk factors for acute graft-versus-host disease and for chronic graft-versus-host disease according to National Institutes of Health consensus criteria.
Blood 2011;117(11):3214-9.
2010: Korashon L Watts; Colleen Delaney; R Keith Humphries; Irwin D Bernstein; Hans-Peter Kiem
Combination of HOXB4 and Delta-1 ligand improves expansion of cord blood cells.
Blood 2010;116(26):5859-66.
2010: P S Becker; J A Taylor; Grant Trobridge; X Zhao; B C Beard; S Chien; J Adair; D B Kohn; J E Wagner; A Shimamura; Hans-Peter Kiem
Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector.
Gene therapy 2010;17(10):1244-52.
2010: Dario Sangiolo; Rainer Storb; H Joachim Deeg; Mary E D Flowers; Paul J Martin; Brenda M Sandmaier; Hans-Peter Kiem; Richard A Nash; Kristine C Doney; Wendy Leisenring; George E Georges
Outcome of allogeneic hematopoietic cell transplantation from HLA-identical siblings for severe aplastic anemia in patients over 40 years of age.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(10):1411-8.
2010: Hans-Peter Kiem; Christina Ironside; Brian C Beard; Grant Trobridge
A retroviral vector common integration site between leupaxin and zinc finger protein 91 (ZFP91) observed in baboon hematopoietic repopulating cells.
Experimental hematology 2010;38(9):819-22, 822.e1-3.
2010: Monica S Thakar; Erlinda B Santos; Theodore A Gooley; George Sale; Rainer Storb; Hans-Peter Kiem; Brenda M Sandmaier
Evaluation of posttransplant methotrexate to facilitate engraftment in the canine major histocompatibility complex-haploidentical nonmyeloablative transplant model.
Transplantation 2010;90(1):14-22.
2010: Grant Trobridge; Robert A Wu; Michael Hansen; Christina Ironside; Korashon L Watts; Philip Olsen; Brian C Beard; Hans-Peter Kiem
Cocal-pseudotyped lentiviral vectors resist inactivation by human serum and efficiently transduce primate hematopoietic repopulating cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(4):725-33.
2010: Joerg Enssle; Grant Trobridge; Kirsten A Keyser; Christina Ironside; Brian C Beard; Hans-Peter Kiem
Stable marking and transgene expression without progression to monoclonality in canine long-term hematopoietic repopulating cells transduced with lentiviral vectors.
Human gene therapy 2010;21(4):397-403.
2010: Hans-Peter Kiem; R A Wu; G Sun; D von Laer; J J Rossi; Grant Trobridge
Foamy combinatorial anti-HIV vectors with MGMTP140K potently inhibit HIV-1 and SHIV replication and mediate selection in vivo.
Gene therapy 2010;17(1):37-49.
2009: Giovanna Travi; Steven A Pergam; Hu Xie; Paul Carpenter; Hans-Peter Kiem; Lawrence Corey; Michael Boeckh
The effect of imatinib on cytomegalovirus reactivation in hematopoietic cell transplantation.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009;49(11):e120-3.
2009: Nina M Muñoz; Grant Trobridge; Hans-Peter Kiem
Ex vivo expansion and lentiviral transduction of Macaca nemestrina CD4+ T cells.
Journal of medical primatology 2009;38(6):438-43.
2009: K L Watts; Brian C Beard; Brent L Wood; Hans-Peter Kiem
Myeloablative irradiation in non-human primates.
Journal of medical primatology 2009;38(6):425-32.
2009: Renee Rosemary Hukkanen; Maggie Gillen; Richard Grant; H Denny Liggitt; Hans-Peter Kiem; Stephen T Kelley
Simian varicella virus in pigtailed macaques (Macaca nemestrina): clinical, pathologic, and virologic features.
Comparative medicine 2009;59(5):482-7.
2009: Monica S Thakar; Xiao-Bing Zhang; Brian C Beard; George E Sale; Erlinda B Santos; Laura Peterson; Hans-Peter Kiem; Brenda M Sandmaier
Transmission and expansion of HOXB4-induced leukemia in two immunosuppressed dogs: implications for a new canine leukemia model.
Experimental hematology 2009;37(10):1157-66.
2009: Halvard Bonig; Gregory V Priestley; Martin Wohlfahrt; Hans-Peter Kiem; Thalia Papayannopoulou
Blockade of alpha6-integrin reveals diversity in homing patterns among human, baboon, and murine cells.
Stem cells and development 2009;18(6):839-44.
2009: Fabrizio Carnevale-Schianca; Wendy Leisenring; Paul J Martin; Terry Furlong; Gary Schoch; Claudio Anasetti; Frederick R Appelbaum; Paul A Carpenter; H Joachim Deeg; Hans-Peter Kiem; Rainer Storb; George B McDonald; Richard A Nash
Longitudinal assessment of morbidity and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation: retrospective analysis of a multicenter phase III study.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(6):749-56.
2009: ZongYi Li; Ying Liu; Sebastian Tuve; Ye Xun; Xiaolong Fan; Liang Min; Qinghua Feng; Nancy B Kiviat; Hans-Peter Kiem; Mary Leonora Disis; André Lieber
Toward a stem cell gene therapy for breast cancer.
Blood 2009;113(22):5423-33.
2009: Brian C Beard; Reeteka Sud; Kirsten A Keyser; Christina Ironside; Tobias Neff; Sabine Gerull; Grant Trobridge; Hans-Peter Kiem
Long-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipients.
Blood 2009;113(21):5094-103.
2009: Grant Trobridge; James Allen; Laura Peterson; Christina Ironside; David W Russell; Hans-Peter Kiem
Foamy and lentiviral vectors transduce canine long-term repopulating cells at similar efficiency.
Human gene therapy 2009;20(5):519-23.
2009: Grant Trobridge; Robert A Wu; Brian C Beard; Sum Ying Chiu; Nina M Muñoz; Dorothee von Laer; John J Rossi; Hans-Peter Kiem
Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection.
PloS one 2009;4(11):e7693.
2009: Brian C Beard; Hans-Peter Kiem
Canine models of gene-modified hematopoiesis.
Methods in molecular biology (Clifton, N.J.) 2009;506():341-61.
2008: Mary E D Flowers; Barry Storer; Paul Carpenter; Andrew R Rezvani; Afonso C Vigorito; Paulo V Campregher; Carina Moravec; Hans-Peter Kiem; Matthew Fero; George Georges; Edus H Warren; Stephanie Lee; Jean E Sanders; Fred Appelbaum; Paul J Martin
Treatment change as a predictor of outcome among patients with classic chronic graft-versus-host disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(12):1380-4.
2008: Sudeshna Seal; David M Hockenbery; Emily Y Spaulding; Hans-Peter Kiem; Nissa Abbassi; H Joachim Deeg
Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals.
Experimental hematology 2008;36(12):1660-72.
2008: Pau Mezquita; Brian C Beard; Hans-Peter Kiem
NOD/SCID repopulating cells contribute only to short-term repopulation in the baboon.
Gene therapy 2008;15(21):1460-2.
2008: Hongje Wang; Hua Cao; Martin Wohlfahrt; Hans-Peter Kiem; André Lieber
Tightly regulated gene expression in human hematopoietic stem cells after transduction with helper-dependent Ad5/35 vectors.
Experimental hematology 2008;36(7):823-31.
2008: Grant Trobridge; Brian C Beard; Christina Gooch; Martin Wohlfahrt; Philip Olsen; James Fletcher; Punam Malik; Hans-Peter Kiem
Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors.
Blood 2008;111(12):5537-43.
2008: Terry Furlong; Hans-Peter Kiem; Frederick R Appelbaum; Paul A Carpenter; H Joachim Deeg; Kristine C Doney; Mary E D Flowers; Marco Mielcarek; Richard A Nash; Rainer Storb; Paul J Martin
Sirolimus in combination with cyclosporine or tacrolimus plus methotrexate for prevention of graft-versus-host disease following hematopoietic cell transplantation from unrelated donors.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(5):531-7.
2008: Xiao-Bing Zhang; Brian C Beard; Grant Trobridge; Brent L Wood; George E Sale; Reeteka Sud; R Keith Humphries; Hans-Peter Kiem
High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector.
The Journal of clinical investigation 2008;118(4):1502-10.
2008: Julia C Piasecki; Karen Beagles; Brian C Beard; Stanley R Riddell; Hans-Peter Kiem
Induction of transgene-specific cytotoxic T lymphocyte responses after transplantation of gene-modified CD34+ cells despite nonablative immunosuppressive conditioning.
Human gene therapy 2008;19(1):103-7.
2007: Peter A Horn; Constança Figueiredo; Hans-Peter Kiem
Gene therapy in the transplantation of allogeneic organs and stem cells.
Current gene therapy 2007;7(6):458-68.
2007: Carmen M S Bonfim; Carlos R de Medeiros; Marco A Bitencourt; José Zanis Neto; Vaneuza A M Funke; Daniela C Setubal; Jefferson Ruiz; Jean E Sanders; Mary E D Flowers; Hans-Peter Kiem; Rainer Storb; Ricardo Pasquini
HLA-matched related donor hematopoietic cell transplantation in 43 patients with Fanconi anemia conditioned with 60 mg/kg of cyclophosphamide.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2007;13(12):1455-60.
2007: Dario Sangiolo; Marina Lesnikova; Richard A Nash; Michael C Jensen; A Nikitine; Hans-Peter Kiem; George E Georges
Lentiviral vector conferring resistance to mycophenolate mofetil and sensitivity to ganciclovir for in vivo T-cell selection.
Gene therapy 2007;14(21):1549-54.
2007: Martin E Wohlfahrt; Brian C Beard; André Lieber; Hans-Peter Kiem
A capsid-modified, conditionally replicating oncolytic adenovirus vector expressing TRAIL Leads to enhanced cancer cell killing in human glioblastoma models.
Cancer research 2007;67(18):8783-90.
2007: Bryan E Shepherd; Hans-Peter Kiem; Peter M Lansdorp; Cynthia E Dunbar; Geraldine Aubert; Andre Larochelle; Ruth Seggewiss; Peter Guttorp; Janis L Abkowitz
Hematopoietic stem-cell behavior in nonhuman primates.
Blood 2007;110(6):1806-13.
2007: Xiao-Bing Zhang; Jeffrey L Schwartz; R Keith Humphries; Hans-Peter Kiem
Effects of HOXB4 overexpression on ex vivo expansion and immortalization of hematopoietic cells from different species.
Stem cells (Dayton, Ohio) 2007;25(8):2074-81.
2007: Chul Won Jung; Brian C Beard; Julia C Morris; Tobias Neff; Katherine Beebe; Barry E Storer; Hans-Peter Kiem
Hematopoietic stem cell engraftment: a direct comparison between intramarrow and intravenous injection in nonhuman primates.
Experimental hematology 2007;35(7):1132-9.
2007: Brian C Beard; David Dickerson; Kate Beebe; Christina Gooch; James Fletcher; Tulin Okbinoglu; Daniel G Miller; Michael A Jacobs; Rajinder Kaul; Hans-Peter Kiem; Grant Trobridge
Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(7):1356-65.
2007: Sabine Gerull; Brian C Beard; Laura J Peterson; Tobias Neff; Hans-Peter Kiem
In vivo selection and chemoprotection after drug resistance gene therapy in a nonmyeloablative allogeneic transplantation setting in dogs.
Human gene therapy 2007;18(5):451-6.
2007: Brian C Beard; Kirsten A Keyser; Grant Trobridge; Laura J Peterson; Daniel G Miller; Michael Jacobs; Rajinder Kaul; Hans-Peter Kiem
Unique integration profiles in a canine model of long-term repopulating cells transduced with gammaretrovirus, lentivirus, or foamy virus.
Human gene therapy 2007;18(5):423-34.
2007: Shao-xu Ying; Sudeshna Seal; Nissa Abbassi; David M Hockenbery; Hans-Peter Kiem; Xiao Li; John M Pagel; Ajay K Gopal; H Joachim Deeg
Differential effects of bexarotene on intrinsic and extrinsic pathways in TRAIL-induced apoptosis in two myeloid leukemia cell lines.
Leukemia & lymphoma 2007;48(5):1003-14.
2007: Tobias Neff; Sabine Gerull; Laura J Peterson; Hans-Peter Kiem
Improved short-term engraftment of lentivirally versus gammaretrovirally transduced allogeneic canine repopulating cells.
The journal of gene medicine 2007;9(5):357-61.
2007: Mari Aker; Julie Tubb; Amy C Groth; Anatoly A Bukovsky; Adam C Bell; Gary Felsenfeld; Hans-Peter Kiem; George Stamatoyannopoulos; David W Emery
Extended core sequences from the cHS4 insulator are necessary for protecting retroviral vectors from silencing position effects.
Human gene therapy 2007;18(4):333-43.
2007: Kirsten A Keyser; Karen E Beagles; Hans-Peter Kiem
Comparison of mesenchymal stem cells from different tissues to suppress T-cell activation.
Cell transplantation 2007;16(5):555-62.
2007: Hans-Peter Kiem; James Allen; Grant Trobridge; Erik Olson; Kirsten A Keyser; Laura Peterson; David W Russell
Foamy-virus-mediated gene transfer to canine repopulating cells.
Blood 2007;109(1):65-70.
2006: Jan Storek; Hans-Peter Kiem
Transgene expression by a large fraction of dendritic cells following autologous transplantation of retrovirally transduced CD34 cells.
Stem cells and development 2006;15(5):619-21.
2006: Alexander M Spence; Hans-Peter Kiem; Sonia Partap; Scott M Schuetze; John R Silber; Richard A Peterson
Complications of a temozolomide overdose: a case report.
Journal of neuro-oncology 2006;80(1):57-61.
2006: Brian C Beard; Pau Mezquita; Julia C Morris; Hans-Peter Kiem
Efficient transduction and engraftment of G-CSF-mobilized peripheral blood CD34+ cells in nonhuman primates using GALV-pseudotyped gammaretroviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(2):212-7.
2006: Peter A Horn; Hans-Peter Kiem
Expansion of SCID repopulating cells does not prove expansion of hematopoietic stem cells.
Blood 2006;108(2):771; author reply 771-2.
2006: Dimitris G Placantonakis; Anatoly A Bukovsky; Sue A Aicher; Hans-Peter Kiem; John P Welsh
Continuous electrical oscillations emerge from a coupled network: a study of the inferior olive using lentiviral knockdown of connexin36.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(19):5008-16.
2006: Xiao-Bing Zhang; Brian C Beard; Katherine Beebe; Barry Storer; R Keith Humphries; Hans-Peter Kiem
Differential effects of HOXB4 on nonhuman primate short- and long-term repopulating cells.
PLoS medicine 2006;3(5):e173.
2006: H Joachim Deeg; Barry E Storer; Michael Boeckh; Paul J Martin; Jeannine S McCune; David Myerson; Shelly Heimfeld; Mary E D Flowers; Claudio Anasetti; Kristine C Doney; John A Hansen; Hans-Peter Kiem; Richard A Nash; Paul V O'Donnell; Jerald P Radich; Brenda M Sandmaier; Bart L Scott; Mohamed L Sorror; Edus H Warren; Robert P Witherspoon; Ann Woolfrey; Frederick R Appelbaum; Rainer Storb
Reduced incidence of acute and chronic graft-versus-host disease with the addition of thymoglobulin to a targeted busulfan/cyclophosphamide regimen.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(5):573-84.
2006: Tobias Neff; Brian C Beard; Hans-Peter Kiem
Survival of the fittest: in vivo selection and stem cell gene therapy.
Blood 2006;107(5):1751-60.
2006: Peter Kurre; Ponni Anandakumar; Hans-Peter Kiem
Rapid 1-hour transduction of whole bone marrow leads to long-term repopulation of murine recipients with lentivirus-modified hematopoietic stem cells.
Gene therapy 2006;13(4):369-73.
2006: Grant Trobridge; Daniel G Miller; Michael A Jacobs; James M Allen; Hans-Peter Kiem; Rajinder Kaul; David W Russell
Foamy virus vector integration sites in normal human cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(5):1498-503.
2005: Grant Trobridge; Brian C Beard; Hans-Peter Kiem
Hematopoietic stem cell transduction and amplification in large animal models.
Human gene therapy 2005;16(12):1355-66.
2005: Richard A Nash; Laura Johnston; Pablo Parker; Jeannine S McCune; Barry Storer; John T Slattery; Terry Furlong; Claudio Anasetti; Frederick R Appelbaum; Michele E Lloid; H Joachim Deeg; Hans-Peter Kiem; Paul J Martin; Mark M Schubert; Robert P Witherspoon; Stephen J Forman; Karl G Blume; Rainer Storb
A phase I/II study of mycophenolate mofetil in combination with cyclosporine for prophylaxis of acute graft-versus-host disease after myeloablative conditioning and allogeneic hematopoietic cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(7):495-505.
2005: José Zanis Neto; Mary E D Flowers; Carlos R Medeiros; Marco A Bitencourt; Carmen M S Bonfim; Daniela C Setúbal; Vaneuza A M Funke; J Sanders; H J Deeg; Hans-Peter Kiem; P Martin; W Leisenring; Rainer Storb; Ricardo Pasquini
Low-dose cyclophosphamide conditioning for haematopoietic cell transplantation from HLA-matched related donors in patients with Fanconi anaemia.
British journal of haematology 2005;130(1):99-106.
2005: K E Beagles; Laura Peterson; X Zhang; Julia Morris; Hans-Peter Kiem
Cyclosporine inhibits the development of green fluorescent protein (GFP)-specific immune responses after transplantation of GFP-expressing hematopoietic repopulating cells in dogs.
Human gene therapy 2005;16(6):725-33.
2005: Shaoheng Ni; Kathrin Maria Bernt; Anuj Gaggar; Zong-Yi Li; Hans-Peter Kiem; André Lieber
Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons.
Human gene therapy 2005;16(6):664-77.
2005: Tomas Kalina; Hailing Lu; Zhao Zhao; Earl Blewett; Dirk P Dittmer; Julie Randolph-Habecker; David G Maloney; Robert G Andrews; Hans-Peter Kiem; Jan Storek
De novo generation of CD4 T cells against viruses present in the host during immune reconstitution.
Blood 2005;105(6):2410-4.
2005: Tobias Neff; Brian C Beard; Laura J Peterson; Ponni Anandakumar; Jesse Thompson; Hans-Peter Kiem
Polyclonal chemoprotection against temozolomide in a large-animal model of drug resistance gene therapy.
Blood 2005;105(3):997-1002.
2005: Kirsten A Keyser; J C Morris; Hans-Peter Kiem
Genetically modified CD34+ cells do not contribute to the mesenchymal compartment after autologous transplantation in the baboon.
Cytotherapy 2005;7(4):345-52.
2005: Michael A Harkey; Maciej Czerwinski; John Slattery; Hans-Peter Kiem
Overexpression of glutathione-S-transferase, MGSTII, confers resistance to busulfan and melphalan.
Cancer investigation 2005;23(1):19-25.
2005: Hailing Lu; Zhao Zhao; Tomas Kalina; Thurman Gillespy; Denny Liggitt; Robert G Andrews; David G Maloney; Hans-Peter Kiem; Jan Storek
Interleukin-7 improves reconstitution of antiviral CD4 T cells.
Clinical immunology (Orlando, Fla.) 2005;114(1):30-41.
2004: Betty L Stewart; Barry Storer; Jan Storek; H Joachim Deeg; Rainer Storb; John A Hansen; Frederick R Appelbaum; Paul A Carpenter; Jean E Sanders; Hans-Peter Kiem; Richard A Nash; Effie W Petersdorf; Carina Moravec; A James Morton; Claudio Anasetti; Mary E D Flowers; Paul J Martin
Duration of immunosuppressive treatment for chronic graft-versus-host disease.
Blood 2004;104(12):3501-6.
2004: Robert E Richard; R Angelo De Claro; James Yan; Sylvia Chien; Horst Von Recum; Julia Morris; Hans-Peter Kiem; David C Dalgarno; Shelly Heimfeld; Tim Clackson; Robert Andrews; C Anthony Blau
Differences in F36VMpl-based in vivo selection among large animal models.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(4):730-40.
2004: Uwe Platzbecker; Peter Kurre; Philippe Guardiola; Jessica L Ward; Jerald P Radich; Hans-Peter Kiem; H Joachim Deeg
Fanconi anemia type C-deficient hematopoietic cells are resistant to TRAIL (TNF-related apoptosis-inducing ligand)-induced cleavage of pro-caspase-8.
Experimental hematology 2004;32(9):815-21.
2004: Peter A Horn; Julia C Morris; Tobias Neff; Hans-Peter Kiem
Stem cell gene transfer--efficacy and safety in large animal studies.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(3):417-31.
2004: Helle Bielefeldt-Ohmann; Mike Gough; M Durning; S Kelley; H Denny Liggitt; Hans-Peter Kiem
Greater sensitivity of pigtailed macaques (Macaca nemestrina) than baboons to total body irradiation.
Journal of comparative pathology 2004;131(1):77-86.
2004: Jo Ellen Schielke; Hans-Peter Kiem; Denny Liggitt; Helle Bielefeldt-Ohmann
Radiation-induced glioblastoma multiforme in two adult baboons (Papio cynocephalus anubis).
Comparative medicine 2004;54(3):327-32.
2004: Peter Kurre; Ponni Anandakumar; Michael A Harkey; Bobbie Thomasson; Hans-Peter Kiem
Efficient marking of murine long-term repopulating stem cells targeting unseparated marrow cells at low lentiviral vector particle concentration.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(6):914-22.
2004: Peter A Horn; Kirsten A Keyser; Laura J Peterson; Tobias Neff; Bobbie Thomasson; Jesse Thompson; Hans-Peter Kiem
Efficient lentiviral gene transfer to canine repopulating cells using an overnight transduction protocol.
Blood 2004;103(10):3710-6.
2004: Dimitris G Placantonakis; Anatoly A Bukovsky; Xiao-Hui Zeng; Hans-Peter Kiem; John P Welsh
Fundamental role of inferior olive connexin 36 in muscle coherence during tremor.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(18):7164-9.
2004: Hans-Peter Kiem; Stephanie Sellers; Bobbie Thomasson; Julia C Morris; John F Tisdale; Peter A Horn; Peiman Hematti; Rima Adler; Ken Kuramoto; Boris Calmels; Aylin Bonifacino; Jiong Hu; Christof von Kalle; Manfred Schmidt; Brian P Sorrentino; Arthur W Nienhuis; C Anthony Blau; Robert G Andrews; Robert E Donahue; Cynthia E Dunbar
Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(3):389-95.
2004: Tobias Neff; Laura J Peterson; Julia C Morris; Jesse Thompson; Xiaobing Zhang; Peter A Horn; Bobbie Thomasson; Hans-Peter Kiem
Efficient gene transfer to hematopoietic repopulating cells using concentrated RD114-pseudotype vectors produced by human packaging cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(2):157-9.
2004: Julia C Morris; Melissa Conerly; Bobbie Thomasson; Jan Storek; Stanley R Riddell; Hans-Peter Kiem
Induction of cytotoxic T-lymphocyte responses to enhanced green and yellow fluorescent proteins after myeloablative conditioning.
Blood 2004;103(2):492-9.
2003: Peter A Horn; Bobbie Thomasson; Brent L Wood; Robert G Andrews; Julia C Morris; Hans-Peter Kiem
Distinct hematopoietic stem/progenitor cell populations are responsible for repopulating NOD/SCID mice compared with nonhuman primates.
Blood 2003;102(13):4329-35.
2003: H Joachim Deeg; Theodore A Gooley; Mary E D Flowers; George E Sale; John T Slattery; Claudio Anasetti; Thomas R Chauncey; Kristine C Doney; George E Georges; Hans-Peter Kiem; Paul J Martin; Effie W Petersdorf; Jerald P Radich; Jean E Sanders; Brenda M Sandmaier; Edus H Warren; Robert P Witherspoon; Rainer Storb; Frederick R Appelbaum
Allogeneic hematopoietic stem cell transplantation for myelofibrosis.
Blood 2003;102(12):3912-8.
2003: Bobbie Thomasson; Laura Peterson; Jesse Thompson; Martin Goerner; Hans-Peter Kiem
Direct comparison of steady-state marrow, primed marrow, and mobilized peripheral blood for transduction of hematopoietic stem cells in dogs.
Human gene therapy 2003;14(17):1683-6.
2003: Tobias Neff; Peter A Horn; Laura J Peterson; Bobbie Thomasson; Jesse Thompson; David A Williams; Manfred Schmidt; George E Georges; Christof von Kalle; Hans-Peter Kiem
Methylguanine methyltransferase-mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model.
The Journal of clinical investigation 2003;112(10):1581-8.
2003: Peter Kurre; Julia Morris; Bobbie Thomasson; Donald B Kohn; Hans-Peter Kiem
Scaffold attachment region-containing retrovirus vectors improve long-term proviral expression after transplantation of GFP-modified CD34+ baboon repopulating cells.
Blood 2003;102(9):3117-9.
2003: Donald B Kohn; Michel Sadelain; Cynthia Dunbar; David M Bodine; Hans-Peter Kiem; Fabio Candotti; John F Tisdale; Isabelle Riviére; C Anthony Blau; Robert E Richard; Brian P Sorrentino; Jan A Nolta; Harry L Malech; Malcolm Brenner; Kenneth Cornetta; Joy Cavagnaro; Katherine High; Joseph C Glorioso
American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(2):180-7.
2003: Peter Kurre; Michael Allen Pulsipher; Ann Woolfrey; Michael B Maris; Brenda M Sandmaier; Hans-Peter Kiem; Rainier Storb
Reduced toxicity and prompt engraftment after minimal conditioning of a patient with Fanconi anemia undergoing hematopoietic stem cell transplantation from an HLA-matched unrelated donor.
Journal of pediatric hematology/oncology 2003;25(7):581-3.
2003: Jan Storek; Thurman Gillespy; Hailing Lu; Ansamma Joseph; Monja A Dawson; Mike Gough; Julia Morris; Robert C Hackman; Peter A Horn; George E Sale; Robert G Andrews; David G Maloney; Hans-Peter Kiem
Interleukin-7 improves CD4 T-cell reconstitution after autologous CD34 cell transplantation in monkeys.
Blood 2003;101(10):4209-18.
2003: Manfred Schmidt; Hanno Glimm; Manuela Wissler; Gesa Hoffmann; Karin Olsson; Stephanie Sellers; Denise A Carbonaro; John F Tisdale; Cordula Leurs; Helmut Hanenberg; Cynthia E Dunbar; Hans-Peter Kiem; Stefan Karlsson; Donald B Kohn; David Williams; Christof von Kalle
Efficient characterization of retro-, lenti-, and foamyvector-transduced cell populations by high-accuracy insertion site sequencing.
Annals of the New York Academy of Sciences 2003;996():112-21.
2002: Peter A Horn; Max S Topp; Julia C Morris; Stanley R Riddell; Hans-Peter Kiem
Highly efficient gene transfer into baboon marrow repopulating cells using GALV-pseudotype oncoretroviral vectors produced by human packaging cells.
Blood 2002;100(12):3960-7.
2002: Peter Kurre; Ponni Anandakumar; Markus Grompe; Hans-Peter Kiem
In vivo administration of interferon gamma does not cause marrow aplasia in mice with a targeted disruption of FANCC.
Experimental hematology 2002;30(11):1257-62.
2002: Peter A Horn; Julia C Morris; A A Bukovsky; Robert G Andrews; L Naldini; Peter Kurre; Hans-Peter Kiem
Lentivirus-mediated gene transfer into hematopoietic repopulating cells in baboons.
Gene therapy 2002;9(21):1464-71.
2002: Manfred Schmidt; Philipp Zickler; Gesa Hoffmann; Sebastian Haas; Manuela Wissler; Arne Muessig; John F Tisdale; Ken Kuramoto; Robert G Andrews; Tong Wu; Hans-Peter Kiem; Cynthia E Dunbar; Christof von Kalle
Polyclonal long-term repopulating stem cell clones in a primate model.
Blood 2002;100(8):2737-43.
2002: Tobias Neff; Peter A Horn; Victor E Valli; Allen M Gown; Scott Wardwell; Brent L Wood; Christof von Kalle; Manfred Schmidt; Laura J Peterson; Julia C Morris; Robert E Richard; Tim Clackson; Hans-Peter Kiem; C Anthony Blau
Pharmacologically regulated in vivo selection in a large animal.
Blood 2002;100(6):2026-31.
2002: Eisei Kondo; Max S Topp; Hans-Peter Kiem; Yuichi Obata; Yasuo Morishima; Kiyotaka Kuzushima; Mitsune Tanimoto; Mine Harada; Toshitada Takahashi; Yoshiki Akatsuka
Efficient generation of antigen-specific cytotoxic T cells using retrovirally transduced CD40-activated B cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(4):2164-71.
2002: H Joachim Deeg; Barry Storer; John T Slattery; Claudio Anasetti; Kristine C Doney; John A Hansen; Hans-Peter Kiem; Paul J Martin; Effie W Petersdorf; Jerald P Radich; Jean E Sanders; Howard M Shulman; Edus H Warren; Robert P Witherspoon; Eileen Bryant; Thomas R Chauncey; Lisa Getzendaner; Rainer Storb; Frederick R Appelbaum
Conditioning with targeted busulfan and cyclophosphamide for hemopoietic stem cell transplantation from related and unrelated donors in patients with myelodysplastic syndrome.
Blood 2002;100(4):1201-7.
2002: Peter Kurre; Julia Morris; Robert G Andrews; Donald B Kohn; Hans-Peter Kiem
Kinetics of fluorescence expression in nonhuman primates transplanted with GFP retrovirus-modified CD34 cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(1):83-90.
2002: Hans-Peter Kiem; John Rasko; Julia Morris; Laura Peterson; Peter Kurre; Robert G Andrews
Ex vivo selection for oncoretrovirally transduced green fluorescent protein-expressing CD34-enriched cells increases short-term engraftment of transduced cells in baboons.
Human gene therapy 2002;13(8):891-9.
2002: Terry Furlong; Wendy Leisenring; Rainer Storb; Claudio Anasetti; Frederick R Appelbaum; Paul A Carpenter; H Joachim Deeg; Kristine C Doney; Hans-Peter Kiem; Richard A Nash; Jean E Sanders; Robert P Witherspoon; Dianne Thompson; Paul J Martin
Psoralen and ultraviolet A irradiation (PUVA) as therapy for steroid-resistant cutaneous acute graft-versus-host disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2002;8(4):206-12.
2002: Martin Goerner; Ted Gooley; Mary E D Flowers; Keith M Sullivan; Hans-Peter Kiem; Jean E Sanders; Paul J Martin; Rainer Storb
Morbidity and mortality of chronic GVHD after hematopoietic stem cell transplantation from HLA-identical siblings for patients with aplastic or refractory anemias.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2002;8(1):47-56.
2001: George E Georges; Rainer Storb; Benedetto Bruno; S J Brodie; J D Thompson; Anna G Taranova; Jan M Zaucha; Marie-Térèse Little; Eustacia Zellmer; Peter F Moore; Ted Gooley; George E Sale; Hans-Peter Kiem; Brenda M Sandmaier; R M Lyons; Richard A Nash
Engraftment of DLA-haploidentical marrow with ex vivo expanded, retrovirally transduced cytotoxic T lymphocytes.
Blood 2001;98(12):3447-55.
2001: Martin Goerner; Peter A Horn; Laura Peterson; Peter Kurre; Rainer Storb; John Rasko; Hans-Peter Kiem
Sustained multilineage gene persistence and expression in dogs transplanted with CD34(+) marrow cells transduced by RD114-pseudotype oncoretrovirus vectors.
Blood 2001;98(7):2065-70.
2001: Lyle Feinstein; Brenda M Sandmaier; David Maloney; Peter A McSweeney; Michael B Maris; Christopher R Flowers; Jerald P Radich; Marie-Térèse Little; Richard A Nash; Thomas R Chauncey; Ann Woolfrey; George E Georges; Hans-Peter Kiem; Jan M Zaucha; Karl G Blume; Judith A Shizuru; Dietger Niederwieser; Rainer Storb
Nonmyeloablative hematopoietic cell transplantation. Replacing high-dose cytotoxic therapy by the graft-versus-tumor effect.
Annals of the New York Academy of Sciences 2001;938():328-37; discussion 337-9.
2001: Peter Kurre; Julia Morris; Peter A Horn; Michael A Harkey; Robert G Andrews; Hans-Peter Kiem
Gene transfer into baboon repopulating cells: A comparison of Flt-3 Ligand and megakaryocyte growth and development factor versus IL-3 during ex vivo transduction.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(6):920-7.
2001: Peter A McSweeney; Dietger Niederwieser; Judith A Shizuru; Brenda M Sandmaier; A J Molina; David G Maloney; Thomas R Chauncey; Theodore A Gooley; Ute Hegenbart; Richard A Nash; Jerald P Radich; JL Wagner; S Minor; Frederick R Appelbaum; William I Bensinger; Eileen Bryant; Mary E D Flowers; George E Georges; F Carl Grumet; Hans-Peter Kiem; Beverly Torok-Storb; Cong Yu; Karl G Blume; Rainer Storb
Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects.
Blood 2001;97(11):3390-400.
2001: Peter Kurre; Julia Morris; A Dusty Miller; Hans-Peter Kiem
Envelope fusion protein binding studies in an inducible model of retrovirus receptor expression and in CD34(+) cells emphasize limited transduction at low receptor levels.
Gene therapy 2001;8(8):593-9.
2001: Benedetto Bruno; Martin Goerner; Richard A Nash; Rainer Storb; Hans-Peter Kiem; Peter A McSweeney
Purified canine CD34+Lin- marrow cells transduced with retroviral vectors give rise to long-term multi-lineage hematopoiesis.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2001;7(10):543-51.
2001: J A Zaucha; Cong Yu; Clinton D Lothrop; Richard A Nash; George E Sale; George E Georges; Hans-Peter Kiem; Glenn P Niemeyer; M Dufresne; Q Cao; Rainer Storb
Severe canine hereditary hemolytic anemia treated by nonmyeloablative marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2001;7(1):14-24.
2001: Carolina Berger; M L Huang; Mike Gough; Philip D Greenberg; Stanley R Riddell; Hans-Peter Kiem
Nonmyeloablative immunosuppressive regimen prolongs In vivo persistence of gene-modified autologous T cells in a nonhuman primate model.
Journal of virology 2001;75(2):799-808.
2000: Martin Goerner; B Roecklein; Beverly Torok-Storb; Shelly Heimfeld; Hans-Peter Kiem
Expansion and transduction of nonenriched human cord blood cells using HS-5 conditioned medium and FLT3-L.
Journal of hematotherapy & stem cell research 2000;9(5):759-65.
2000: Laurence E Shields; Hans-Peter Kiem; Robert G Andrews
Highly efficient gene transfer into preterm CD34 hematopoietic progenitor cells.
American journal of obstetrics and gynecology 2000;183(3):732-7.
2000: Peter Kurre; Hans-Peter Kiem
Progress towards hematopoietic stem cell gene therapy.
Current opinion in molecular therapeutics 2000;2(4):400-11.
2000: Robert G Andrews; Laura J Peterson; Julia Morris; Jennifer Potter; S Heyward; Mike Gough; Eileen Bryant; Hans-Peter Kiem
Differential engraftment of genetically modified CD34(+) and CD34(-) hematopoietic cell subsets in lethally irradiated baboons.
Experimental hematology 2000;28(5):508-18.
2000: Carolina Berger; Suzanne M Xuereb; David C Johnson; K S Watanabe; Hans-Peter Kiem; Philip D Greenberg; Stanley R Riddell
Expression of herpes simplex virus ICP47 and human cytomegalovirus US11 prevents recognition of transgene products by CD8(+) cytotoxic T lymphocytes.
Journal of virology 2000;74(10):4465-73.
1999: Rainer Storb; Cong Yu; Jan M Zaucha; H Joachim Deeg; George E Georges; Hans-Peter Kiem; Richard A Nash; Peter A McSweeney; JL Wagner
Stable mixed hematopoietic chimerism in dogs given donor antigen, CTLA4Ig, and 100 cGy total body irradiation before and pharmacologic immunosuppression after marrow transplant.
Blood 1999;94(7):2523-9.
1999: Martin Goerner; Benedetto Bruno; Peter A McSweeney; G Buron; Rainer Storb; Hans-Peter Kiem
The use of granulocyte colony-stimulating factor during retroviral transduction on fibronectin fragment CH-296 enhances gene transfer into hematopoietic repopulating cells in dogs.
Blood 1999;94(7):2287-92.
1999: Rainer Storb; Cong Yu; T Barnett; JL Wagner; H Joachim Deeg; Richard A Nash; Hans-Peter Kiem; Peter McSweeney; K Seidel; George E Georges; Jan M Zaucha
Stable mixed hematopoietic chimerism in dog leukocyte antigen-identical littermate dogs given lymph node irradiation before and pharmacologic immunosuppression after marrow transplantation.
Blood 1999;94(3):1131-6.
1999: Hans-Peter Kiem; Peter A McSweeney; Benedetto Bruno; Martin Goerner; G Buron; Julia Morris; Rainer Storb; A Dusty Miller
Improved gene transfer into canine hematopoietic repopulating cells using CD34-enriched marrow cells in combination with a gibbon ape leukemia virus-pseudotype retroviral vector.
Gene therapy 1999;6(6):966-72.
1999: A Winkler; Hans-Peter Kiem; Laurence E Shields; Q H Sun; Robert G Andrews
Gene transfer into fetal baboon hematopoietic progenitor cells.
Human gene therapy 1999;10(4):667-77.
1999: Peter Kurre; Hans-Peter Kiem; Julia Morris; S Heyward; JL Battini; A Dusty Miller
Efficient transduction by an amphotropic retrovirus vector is dependent on high-level expression of the cell surface virus receptor.
Journal of virology 1999;73(1):495-500.
1998: Hans-Peter Kiem; Robert G Andrews; Julia Morris; Laura Peterson; S Heyward; J M Allen; John Rasko; Jennifer Potter; A Dusty Miller
Improved gene transfer into baboon marrow repopulating cells using recombinant human fibronectin fragment CH-296 in combination with interleukin-6, stem cell factor, FLT-3 ligand, and megakaryocyte growth and development factor.
Blood 1998;92(6):1878-86.
1998: George E Georges; Rainer Storb; M W Brunvand; Hans-Peter Kiem; Peter F Moore; P Malik; D Ennist; Richard A Nash
Canine T cells transduced with a herpes simplex virus thymidine kinase gene: a model to study effects on engraftment and control of graft-versus-host disease.
Transplantation 1998;66(4):540-4.
1998: Rainer Storb; Cong Yu; H Joachim Deeg; George E Georges; Hans-Peter Kiem; Peter A McSweeney; Richard A Nash; Brenda M Sandmaier; Keith M Sullivan; JL Wagner; M C Walters
Current and future preparative regimens for bone marrow transplantation in thalassemia.
Annals of the New York Academy of Sciences 1998;850():276-87.
1998: Hanno Glimm; K Flügge; Dietrich Möbest; V M Hofmann; J Postmus; Reinhard Henschler; Winand Lange; J Finke; Hans-Peter Kiem; G Schulz; Felicia M Rosenthal; Roland Mertelsmann; Christof von Kalle
Efficient serum-free retroviral gene transfer into primitive human hematopoietic progenitor cells by a defined, high-titer, nonconcentrated vector-containing medium.
Human gene therapy 1998;9(6):771-8.
1997: Hans-Peter Kiem; S Heyward; A Winkler; Jennifer Potter; J M Allen; A Dusty Miller; Robert G Andrews
Gene transfer into marrow repopulating cells: comparison between amphotropic and gibbon ape leukemia virus pseudotyped retroviral vectors in a competitive repopulation assay in baboons.
Blood 1997;90(11):4638-45.
1997: Hanno Glimm; Hans-Peter Kiem; B Darovsky; R Storb; J Wolf; V Diehl; Roland Mertelsmann; Christof von Kalle
Efficient gene transfer in primitive CD34+/CD38lo human bone marrow cells reselected after long-term exposure to GALV-pseudotyped retroviral vector.
Human gene therapy 1997;8(17):2079-86.
1997: Rainer Storb; Cong Yu; JL Wagner; H Joachim Deeg; Richard A Nash; Hans-Peter Kiem; Wendy Leisenring; Howard M Shulman
Stable mixed hematopoietic chimerism in DLA-identical littermate dogs given sublethal total body irradiation before and pharmacological immunosuppression after marrow transplantation.
Blood 1997;89(8):3048-54.
1997: M Czerwinski; Hans-Peter Kiem; John T Slattery
Human CD34+ cells do not express glutathione S-transferases alpha.
Gene therapy 1997;4(3):268-70.
1996: Hans-Peter Kiem; Wendy Leisenring; R Raff; H Joachim Deeg; Friedrich Schuening; Frederick R Appelbaum; Rainer Storb
Failure of recombinant stem cell factor to enhance engraftment of L-leucyl-L-leucine methyl ester treated canine marrow after irradiation.
Blood 1996;88(5):1896-7.
1996: R Shull; X Lu; Ian D Dubé; Carolyn Lutzko; Stephen A Kruth; Anthony Abrams-Ogg; Hans-Peter Kiem; S Goehle; Friedrich Schuening; C Millan; R Carter
Humoral immune response limits gene therapy in canine MPS I.
Blood 1996;88(1):377-9.
1996: Hans-Peter Kiem; George B McDonald; David Myerson; C L Spurgeon; H Joachim Deeg; Jean E Sanders; Kristine C Doney; Frederick R Appelbaum; K M Sullivan; Robert P Witherspoon; Rainer Storb
Marrow transplantation for hepatitis-associated aplastic anemia: a follow-up of long-term survivors.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1996;2(2):93-9.
1996: Hans-Peter Kiem; B Darovsky; Christof von Kalle; S Goehle; T Graham; A Dusty Miller; Rainer Storb; Friedrich Schuening
Long-term persistence of canine hematopoietic cells genetically marked by retrovirus vectors.
Human gene therapy 1996;7(1):89-96.
1995: L A Wagner; Hans-Peter Kiem; P McSweeney; Friedrich Schuening; R Storb; Elaine A Ostrander
Development of a clonality assay for canine hematopoietic stem cells.
Blood 1995;86(8):3265-7.
1995: Hans-Peter Kiem; Christof von Kalle; Friedrich Schuening; Rainer Storb
Gene therapy and bone marrow transplantation.
Current opinion in oncology 1995;7(2):107-14.
1995: J Barquinero; Hans-Peter Kiem; Christof von Kalle; B Darovsky; S Goehle; T Graham; K Seidel; Rainer Storb; Friedrich Schuening
Myelosuppressive conditioning improves autologous engraftment of genetically marked hematopoietic repopulating cells in dogs.
Blood 1995;85(5):1195-201.
1994: Christof von Kalle; Hans-Peter Kiem; S Goehle; B Darovsky; S Heimfeld; Beverly Torok-Storb; Rainer Storb; Friedrich Schuening
Increased gene transfer into human hematopoietic progenitor cells by extended in vitro exposure to a pseudotyped retroviral vector.
Blood 1994;84(9):2890-7.
1994: Hans-Peter Kiem; B Darovsky; Christof von Kalle; S Goehle; D Stewart; T Graham; Robert C Hackman; Frederick R Appelbaum; H Joachim Deeg; A Dusty Miller
Retrovirus-mediated gene transduction into canine peripheral blood repopulating cells.
Blood 1994;83(6):1467-73.