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Laura Kiessling

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TOP 3
Joshua M Fishman; Laura L Kiessling
Synthesis of functionalizable and degradable polymers by ring-opening metathesis polymerization.
Laura L Kiessling; Joseph C Grim
Glycopolymer probes of signal transduction.
Matthew B Kraft; Mario A Martinez Farias; Laura L Kiessling
Synthesis of lipid-linked arabinofuranose donors for glycosyltransferases.

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All Publications

2013: Joshua M Fishman; Laura L Kiessling
Synthesis of functionalizable and degradable polymers by ring-opening metathesis polymerization.
Angewandte Chemie (International ed. in English) 2013;52(19):5061-4.
2013: Laura L Kiessling; Joseph C Grim
Glycopolymer probes of signal transduction.
Chemical Society reviews 2013;42(10):4476-91.
2013: Matthew B Kraft; Mario A Martinez Farias; Laura L Kiessling
Synthesis of lipid-linked arabinofuranose donors for glycosyltransferases.
The Journal of organic chemistry 2013;78(5):2128-33.
2012: Samira Musah; Paul J Wrighton; Daniel B Zwick; Song Jin; Stephen A Morin; Laura L Kiessling
Glycosaminoglycan-binding hydrogels enable mechanical control of human pluripotent stem cell self-renewal.
ACS nano 2012;6(11):10168-77.
2012: Lynne R Prost; Marco Tonelli; Joseph C Grim; Laura L Kiessling
Noncarbohydrate glycomimetics and glycoprotein surrogates as DC-SIGN antagonists and agonists.
ACS chemical biology 2012;7(9):1603-8.
2012: Christopher D Brown; Max S Rusek; Laura L Kiessling
Fluorosugar chain termination agents as probes of the sequence specificity of a carbohydrate polymerase.
Journal of the American Chemical Society 2012;134(15):6552-5.
2012: Margaret L Wong; Ilia A Guzei; Laura L Kiessling
An asymmetric synthesis of L-pyrrolysine.
Organic letters 2012;14(6):1378-81.
2012: Joseph R Klim; Rachael T C Sheridan; Margaret L Wong; Paul J Wrighton; Adam H Courtney; Anthony J Fowler; Laura L Kiessling
Small-molecule-modified surfaces engage cells through the αvβ3 integrin.
ACS chemical biology 2012;7(3):518-25.
2012: John F May; Rebecca A Splain; Christopher D Brown; Matthew R Levengood; Laura L Kiessling
A processive carbohydrate polymerase that mediates bifunctional catalysis using a single active site.
Biochemistry 2012;51(6):1148-59.
2011: Matthew R Levengood; Rebecca A Splain; Laura L Kiessling
Monitoring processivity and length control of a carbohydrate polymerase.
Journal of the American Chemical Society 2011;133(32):12758-66.
2011: Joseph C Grim; Kathleen C A Garber; Laura L Kiessling
Glycomimetic building blocks: a divergent synthesis of epimers of shikimic acid.
Organic letters 2011;13(15):3790-3.
2011: Lingyin Li; Joseph R Klim; Adam H Courtney; Ratmir Derda; Laura L Kiessling
Spatial control of cell fate using synthetic surfaces to potentiate TGF-beta signaling.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(29):11745-50.
2011: Eric S Underbakke; Yimin Zhu; Laura L Kiessling
Protein footprinting in a complex milieu: identifying the interaction surfaces of the chemotaxis adaptor protein CheW.
Journal of molecular biology 2011;409(4):483-95.
2010: Joseph R Klim; Lingyin Li; Paul J Wrighton; Marian S Piekarczyk; Laura L Kiessling
A defined glycosaminoglycan-binding substratum for human pluripotent stem cells.
Nature methods 2010;7(12):989-94.
2010: Lingyin Li; Brendan P Orner; Tao Huang; Andrew Hinck; Laura L Kiessling
Peptide ligands that use a novel binding site to target both TGF-β receptors.
Molecular bioSystems 2010;6(12):2392-402.
2010: Eric S Underbakke; Laura L Kiessling
Classifying chemoreceptors: quantity versus quality.
The EMBO journal 2010;29(20):3435-6.
2010: Kathleen C A Garber; Kittikhun Wangkanont; Erin Carlson; Laura L Kiessling
A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN.
Chemical communications (Cambridge, England) 2010;46(36):6747-9.
2010: Chutima Jiarpinitnun; Laura L Kiessling
Unexpected enhancement in biological activity of a GPCR ligand induced by an oligoethylene glycol substituent.
Journal of the American Chemical Society 2010;132(26):8844-5.
2010: Rebecca A Splain; Laura L Kiessling
Synthesis of galactofuranose-based acceptor substrates for the study of the carbohydrate polymerase GlfT2.
Bioorganic & medicinal chemistry 2010;18(11):3753-9.
2010: Ratmir Derda; Samira Musah; Brendan P Orner; Joseph R Klim; Lingyin Li; Laura L Kiessling
High-throughput discovery of synthetic surfaces that support proliferation of pluripotent cells.
Journal of the American Chemical Society 2010;132(4):1289-95.
2010: Laura L Kiessling; Rebecca A Splain
Chemical approaches to glycobiology.
Annual review of biochemistry 2010;79():619-53.
2009: Todd D Gruber; William M Westler; Laura L Kiessling; Katrina T Forest
X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin.
Biochemistry 2009;48(39):9171-3.
2009: Todd D Gruber; M Jack Borrok; William M Westler; Katrina T Forest; Laura L Kiessling
Ligand binding and substrate discrimination by UDP-galactopyranose mutase.
Journal of molecular biology 2009;391(2):327-40.
2009: John F May; Rebecca A Splain; Christine Brotschi; Laura L Kiessling
A tethering mechanism for length control in a processive carbohydrate polymerization.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(29):11851-6.
2009: M Jack Borrok; Yimin Zhu; Katrina T Forest; Laura L Kiessling
Structure-based design of a periplasmic binding protein antagonist that prevents domain closure.
ACS chemical biology 2009;4(6):447-56.
2009: Erin M Kolonko; Jason K Pontrello; Shane L Mangold; Laura L Kiessling
General synthetic route to cell-permeable block copolymers via ROMP.
Journal of the American Chemical Society 2009;131(21):7327-33.
2009: Adam H Courtney; Erik B Puffer; Jason K Pontrello; Zhi-Qiang Yang; Laura L Kiessling
Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2500-5.
2009: Emily Dykhuizen; Laura L Kiessling
Potent ligands for prokaryotic UDP-galactopyranose mutase that exploit an enzyme subsite.
Organic letters 2009;11(1):193-6.
2008: Emily Dykhuizen; John F May; Aimon Tongpenyai; Laura L Kiessling
Inhibitors of UDP-galactopyranose mutase thwart mycobacterial growth.
Journal of the American Chemical Society 2008;130(21):6706-7.
2008: Erin M Kolonko; Laura L Kiessling
A polymeric domain that promotes cellular internalization.
Journal of the American Chemical Society 2008;130(17):5626-7.
2008: M Jack Borrok; Erin M Kolonko; Laura L Kiessling
Chemical probes of bacterial signal transduction reveal that repellents stabilize and attractants destabilize the chemoreceptor array.
ACS chemical biology 2008;3(2):101-9.
2008: Eric S Underbakke; Yimin Zhu; Laura L Kiessling
Isotope-coded affinity tags with tunable reactivities for protein footprinting.
Angewandte Chemie (International ed. in English) 2008;47(50):9677-80.
2007: M Jack Borrok; Laura L Kiessling
Non-carbohydrate inhibitors of the lectin DC-SIGN.
Journal of the American Chemical Society 2007;129(42):12780-5.
2007: Ratmir Derda; Daniel J Wherritt; Laura L Kiessling
Solid-phase synthesis of alkanethiols for the preparation of self-assembled monolayers.
Langmuir : the ACS journal of surfaces and colloids 2007;23(22):11164-7.
2007: Jennifer M Chad; Karunan Partha Sarathy; Todd D Gruber; Eshwari Addala; Laura L Kiessling; David A R Sanders
Site-directed mutagenesis of UDP-galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues.
Biochemistry 2007;46(23):6723-32.
2007: M Jack Borrok; Laura L Kiessling; Katrina T Forest
Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures.
Protein science : a publication of the Protein Society 2007;16(6):1032-41.
2007: Ratmir Derda; Lingyin Li; Brendan P Orner; Rachel L Lewis; James A Thomson; Laura L Kiessling
Defined substrates for human embryonic stem cell growth identified from surface arrays.
ACS chemical biology 2007;2(5):347-55.
2007: Laura L Kiessling; Jennifer A Doudna; Kai Johnsson; Anna K Mapp; Michael A Marletta; Peter H Seeberger; James R Williamson; Sally Garbo Wedde
A higher degree of difficulty.
ACS chemical biology 2007;2(4):197-9.
2007: Erik B Puffer; Jason K Pontrello; Jessica J Hollenbeck; John A Kink; Laura L Kiessling
Activating B cell signaling with defined multivalent ligands.
ACS chemical biology 2007;2(4):252-62.
2007: Coby B Carlson; Patricia Mowery; Robert M. Owen; Emily Dykhuizen; Laura L Kiessling
Selective tumor cell targeting using low-affinity, multivalent interactions.
ACS chemical biology 2007;2(2):119-27.
2007: Robert M. Owen; Coby B Carlson; Jinwang Xu; Patricia Mowery; Elisabetta Fasella; Laura L Kiessling
Bifunctional ligands that target cells displaying the alpha v beta3 integrin.
Chembiochem : a European journal of chemical biology 2007;8(1):68-82.
2006: Laura L Kiessling; Sally Garbo Wedde; Ronald T Raines
Symbiosis: Chemical biology at Wisconsin.
ACS chemical biology 2006;1(8):481-4.
2006: Brendan P Orner; Lin Liu; Regina M Murphy; Laura L Kiessling
Phage display affords peptides that modulate beta-amyloid aggregation.
Journal of the American Chemical Society 2006;128(36):11882-9.
2006: Erin Carlson; John F May; Laura L Kiessling
Chemical probes of UDP-galactopyranose mutase.
Chemistry & biology 2006;13(8):825-37.
2006: Yi He; Jesse P Wilkins; Laura L Kiessling
N-acylsulfonamide linker activation by Pd-catalyzed allylation.
Organic letters 2006;8(12):2483-5.
2006: Matthew J Allen; Ronald T Raines; Laura L Kiessling
Contrast agents for magnetic resonance imaging synthesized with ring-opening metathesis polymerization.
Journal of the American Chemical Society 2006;128(20):6534-5.
2006: Laura L Kiessling; Jason E Gestwicki; Laura E Strong
Synthetic multivalent ligands as probes of signal transduction.
Angewandte Chemie (International ed. in English) 2006;45(15):2348-68.
2005: Jason K Pontrello; Matthew J Allen; Eric S Underbakke; Laura L Kiessling
Solid-phase synthesis of polymers using the ring-opening metathesis polymerization.
Journal of the American Chemical Society 2005;127(42):14536-7.
2005: Allison C Lamanna; George W Ordal; Laura L Kiessling
Large increases in attractant concentration disrupt the polar localization of bacterial chemoreceptors.
Molecular microbiology 2005;57(3):774-85.
2005: David M Borrok; M Jack Borrok; Jeremy B Fein; Laura L Kiessling
Link between chemotactic response to Ni2+ and its adsorption onto the Escherichia coli cell surface.
Environmental science & technology 2005;39(14):5227-33.
2004: Yi He; Ronald J Hinklin; Jiyoung Chang; Laura L Kiessling
Stereoselective N-glycosylation by Staudinger ligation.
Organic letters 2004;6(24):4479-82.
2004: Brendan P Orner; Ratmir Derda; Rachel L Lewis; James A Thomson; Laura L Kiessling
Arrays for the combinatorial exploration of cell adhesion.
Journal of the American Chemical Society 2004;126(35):10808-9.
2004: Michelle Soltero-Higgin; Erin Carlson; John H Phillips; Laura L Kiessling
Identification of inhibitors for UDP-galactopyranose mutase.
Journal of the American Chemical Society 2004;126(34):10532-3.
2004: Michelle Soltero-Higgin; Erin Carlson; Todd D Gruber; Laura L Kiessling
A unique catalytic mechanism for UDP-galactopyranose mutase.
Nature structural & molecular biology 2004;11(6):539-43.
2004: Patricia Mowery; Zhi-Qiang Yang; Eva J Gordon; Oren Dwir; Andrew G Spencer; Ronen Alon; Laura L Kiessling
Synthetic glycoprotein mimics inhibit L-selectin-mediated rolling and promote L-selectin shedding.
Chemistry & biology 2004;11(5):725-32.
2004: Erin Carlson; Laura L Kiessling
Improved chemical syntheses of 1- and 5-deazariboflavin.
The Journal of organic chemistry 2004;69(7):2614-7.
2004: Byron R Griffith; Benjamin Allen; Alan C Rapraeger; Laura L Kiessling
A polymer scaffold for protein oligomerization.
Journal of the American Chemical Society 2004;126(6):1608-9.
2003: Emily A Smith; William D Thomas; Laura L Kiessling; Robert M Corn
Surface plasmon resonance imaging studies of protein-carbohydrate interactions.
Journal of the American Chemical Society 2003;125(20):6140-8.
2003: Michael C Schuster; David A Mann; Tonia J Buchholz; Kathryn M Johnson; William D Thomas; Laura L Kiessling
Parallel synthesis of glycomimetic libraries: targeting a C-type lectin.
Organic letters 2003;5(9):1407-10.
2003: Jason E Gestwicki; Christopher W Cairo; M Jack Borrok; Laura L Kiessling
Visualization and characterization of receptor clusters by transmission electron microscopy.
Methods in enzymology 2003;362():301-12.
2002: Jason E Gestwicki; Christopher W Cairo; Laura E Strong; Karolyn A Oetjen; Laura L Kiessling
Influencing receptor-ligand binding mechanisms with multivalent ligand architecture.
Journal of the American Chemical Society 2002;124(50):14922-33.
2002: Zhi-Qiang Yang; Erik B Puffer; Jason K Pontrello; Laura L Kiessling
Synthesis of a multivalent display of a CD22-binding trisaccharide.
Carbohydrate research 2002;337(18):1605-13.
2002: Travis Young; Laura L Kiessling
A strategy for the synthesis of sulfated peptides.
Angewandte Chemie (International ed. in English) 2002;41(18):3449-51.
2002: Allison C Lamanna; Jason E Gestwicki; Laura E Strong; Sara L Borchardt; Robert M. Owen; Laura L Kiessling
Conserved amplification of chemotactic responses through chemoreceptor interactions.
Journal of bacteriology 2002;184(18):4981-7.
2002: Robert M. Owen; Jason E Gestwicki; Travis Young; Laura L Kiessling
Synthesis and applications of end-labeled neoglycopolymers.
Organic letters 2002;4(14):2293-6.
2002: Christopher W Cairo; Andrea Strzelec; Regina M Murphy; Laura L Kiessling
Affinity-based inhibition of beta-amyloid toxicity.
Biochemistry 2002;41(27):8620-9.
2002: Jason E Gestwicki; Christopher W Cairo; David A Mann; Robert M. Owen; Laura L Kiessling
Selective immobilization of multivalent ligands for surface plasmon resonance and fluorescence microscopy.
Analytical biochemistry 2002;305(2):149-55.
2002: Ronald J Hinklin; Laura L Kiessling
p-Methoxybenzyl ether cleavage by polymer-supported sulfonamides.
Organic letters 2002;4(7):1131-3.
2002: Laura L Kiessling; Christopher W Cairo
Hitting the sweet spot.
Nature biotechnology 2002;20(3):234-5.
2002: Christopher W Cairo; Jason E Gestwicki; Motomu Kanai; Laura L Kiessling
Control of multivalent interactions by binding epitope density.
Journal of the American Chemical Society 2002;124(8):1615-9.
2002: Jason E Gestwicki; Laura E Strong; Christopher W Cairo; Frederick J Boehm; Laura L Kiessling
Cell aggregation by scaffolded receptor clusters.
Chemistry & biology 2002;9(2):163-9.
2002: Jason E Gestwicki; Laura L Kiessling
Inter-receptor communication through arrays of bacterial chemoreceptors.
Nature 2002;415(6867):81-4.
2001: J G Steinmann; J H Phillips; W J Sanders; Laura L Kiessling
Synthesis of cyclic sulfates by halocyclization.
Organic letters 2001;3(22):3557-9.
2001: Jason E Gestwicki; Laura E Strong; S L Borchardt; Christopher W Cairo; A M Schnoes; Laura L Kiessling
Designed potent multivalent chemoattractants for Escherichia coli.
Bioorganic & medicinal chemistry 2001;9(9):2387-93.
2001: A L Marlow; Laura L Kiessling
Improved chemical synthesis of UDP-galactofuranose.
Organic letters 2001;3(16):2517-9.
2001: T L Lowe; A Strzelec; Laura L Kiessling; Regina M Murphy
Structure-function relationships for inhibitors of beta-amyloid toxicity containing the recognition sequence KLVFF.
Biochemistry 2001;40(26):7882-9.
2001: Ronald J Hinklin; Laura L Kiessling
Glycosyl sulfonylcarbamates: new glycosyl donors with tunable reactivity.
Journal of the American Chemical Society 2001;123(14):3379-80.
2001: Bradley Nilsson; Laura L Kiessling; Ronald T Raines
High-yielding Staudinger ligation of a phosphinothioester and azide to form a peptide.
Organic letters 2001;3(1):9-12.
2000: Laura L Kiessling; Jason E Gestwicki; Laura E Strong
Synthetic multivalent ligands in the exploration of cell-surface interactions.
Current opinion in chemical biology 2000;4(6):696-703.
2000: Jason E Gestwicki; Allison C Lamanna; R M Harshey; L L McCarter; Laura L Kiessling; J Adler
Evolutionary conservation of methyl-accepting chemotaxis protein location in Bacteria and Archaea.
Journal of bacteriology 2000;182(22):6499-502.
2000: Jason E Gestwicki; Laura E Strong; Laura L Kiessling
Tuning chemotactic responses with synthetic multivalent ligands.
Chemistry & biology 2000;7(8):583-91.
2000: N Maki; Jason E Gestwicki; E M Lake; Laura L Kiessling; J Adler
Motility and chemotaxis of filamentous cells of Escherichia coli.
Journal of bacteriology 2000;182(15):4337-42.
2000: Bradley Nilsson; Laura L Kiessling; Ronald T Raines
Staudinger ligation: a peptide from a thioester and azide.
Organic letters 2000;2(13):1939-41.
2000: Eva J Gordon; Jason E Gestwicki; Laura E Strong; Laura L Kiessling
Synthesis of end-labeled multivalent ligands for exploring cell-surface-receptor-ligand interactions.
Chemistry & biology 2000;7(1):9-16.
1999: MM Pallitto; J Ghanta; P Heinzelman; Laura L Kiessling; Regina M Murphy
Recognition sequence design for peptidyl modulators of beta-amyloid aggregation and toxicity.
Biochemistry 1999;38(12):3570-8.
1999: W J Sanders; Eva J Gordon; Oren Dwir; P J Beck; Ronen Alon; Laura L Kiessling
Inhibition of L-selectin-mediated leukocyte rolling by synthetic glycoprotein mimics.
The Journal of biological chemistry 1999;274(9):5271-8.
1998: Eva J Gordon; Laura E Strong; Laura L Kiessling
Glycoprotein-inspired materials promote the proteolytic release of cell surface L-selectin.
Bioorganic & medicinal chemistry 1998;6(8):1293-9.
1998: Eva J Gordon; W J Sanders; Laura L Kiessling
Synthetic ligands point to cell surface strategies.
Nature 1998;392(6671):30-1.
1998: Laura L Kiessling; Eva J Gordon
Transforming the cell surface through proteolysis.
Chemistry & biology 1998;5(3):R49-62.
1997: J W Kurutz; Laura L Kiessling
Solution conformation of Lewis a--derived selectin ligands is unaffected by anionic substituents at the 3'- and 6'-positions.
Glycobiology 1997;7(3):337-47.
1996: W J Sanders; T R Katsumoto; Carolyn R Bertozzi; S D Rosen; Laura L Kiessling
L-selectin-carbohydrate interactions: relevant modifications of the Lewis x trisaccharide.
Biochemistry 1996;35(47):14862-7.
1996: J Ghanta; C L Shen; Laura L Kiessling; Regina M Murphy
A strategy for designing inhibitors of beta-amyloid toxicity.
The Journal of biological chemistry 1996;271(47):29525-8.
1996: Laura L Kiessling; N L Pohl
Strength in numbers: non-natural polyvalent carbohydrate derivatives.
Chemistry & biology 1996;3(2):71-7.