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Thomas Kietzmann
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Living Beings
Chemicals & Drugs
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Network (preview)
25
Jungermann, Kurt
15
Görlach, Agnes
13
Immenschuh, Stephan
10
Dimova, Elitsa
8
Roth, Ulrike
8
Samoylenko, Anatoly
5
Wijayanti, Nastiti
5
Flügel, Daniela
5
Katz, Norbert
5
Hess, John
4
Hirsch-Ernst, Karen
4
BelAiba, Rachida
3
Berchner-Pfannschmidt, Utta
3
Bonello, Steve
3
Djordjevic, Talija
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All Publications
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2009: Ganjam Goutham Kumar; Dimova Elitsa Y; Unterman Terry G; Kietzmann Thomas
FoxO1 and HNF-4 are involved in regulation of hepatic glucokinase gene expression by resveratrol.
The Journal of biological chemistry 2009;284(45):30783-97.
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2009: Naidu Srivatsava; Vijayan Vijith; Santoso Sentot; Kietzmann Thomas; Immenschuh Stephan
Inhibition and genetic deficiency of p38 MAPK up-regulates heme oxygenase-1 gene expression via Nrf2.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(11):7048-57.
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2008: Dimova Elitsa Y; Kietzmann Thomas
Metabolic, hormonal and environmental regulation of plasminogen activator inhibitor-1 (PAI-1) expression: lessons from the liver.
Thrombosis and haemostasis 2008;100(6):992-1006.
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2008: Kietzmann Thomas; Andreasen Peter
Plasminogen activator inhibitor-1 (PAI-1): a molecule at the crossroads to cell survival or cell death.
Thrombosis and haemostasis 2008;100(6):965-8.
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2008: Naidu Srivatsava; Wijayanti Nastiti; Santoso Sentot; Kietzmann Thomas; Immenschuh Stephan
An atypical NF-kappa B-regulated pathway mediates phorbol ester-dependent heme oxygenase-1 gene activation in monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(6):4113-23.
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2008: Klein Alexandra; Flügel Daniela; Kietzmann Thomas
Transcriptional regulation of serine/threonine kinase-15 (STK15) expression by hypoxia and HIF-1.
Molecular biology of the cell 2008;19(9):3667-75.
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2008: Samoylenko Anatoly; Dimova Elitsa Y; Horbach Tina; Teplyuk Nadiya; Immenschuh Stephan; Kietzmann Thomas
Opposite expression of the antioxidant heme oxygenase-1 in primary cells and tumor cells: regulation by interaction of USF-2 and Fra-1.
Antioxidants & redox signaling 2008;10(7):1163-74.
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2008: Jalil Youssef Abdul; Ritz Vera; Jakimenko Ana; Schmitz-Salue Christoph; Siebert Heike; Awuah David; Kotthaus André; Kietzmann Thomas; Ziemann Christina; Hirsch-Ernst Karen I
Vesicular localization of the rat ATP-binding cassette half-transporter rAbcb6.
American journal of physiology. Cell physiology 2008;294(2):C579-90.
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2008: Wijayanti Nastiti; Naidu Srivatsava; Kietzmann Thomas; Immenschuh Stephan
Inhibition of phorbol ester-dependent peroxiredoxin I gene activation by lipopolysaccharide via phosphorylation of RelA/p65 at serine 276 in monocytes.
Free radical biology & medicine 2008;44(4):699-710.
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2007: Belaiba Rachida S; Bonello Steve; Zähringer Christian; Schmidt Stefanie; Hess John; Kietzmann Thomas; Görlach Agnes
Hypoxia up-regulates hypoxia-inducible factor-1alpha transcription by involving phosphatidylinositol 3-kinase and nuclear factor kappaB in pulmonary artery smooth muscle cells.
Molecular biology of the cell 2007;18(12):4691-7.
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2007: Dimova Elitsa Y; Jakubowska Malgorzata M; Kietzmann Thomas
CREB binding to the hypoxia-inducible factor-1 responsive elements in the plasminogen activator inhibitor-1 promoter mediates the glucagon effect.
Thrombosis and haemostasis 2007;98(2):296-303.
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2007: Lenart Jacek; Dombrowski Frank; Görlach Agnes; Kietzmann Thomas
Deficiency of manganese superoxide dismutase in hepatocytes disrupts zonated gene expression in mouse liver.
Archives of biochemistry and biophysics 2007;462(2):238-44.
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2007: Flügel Daniela; Görlach Agnes; Michiels Carine; Kietzmann Thomas
Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner.
Molecular and cellular biology 2007;27(9):3253-65.
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2007: Bonello Steve; Zähringer Christian; BelAiba Rachida S; Djordjevic Talija; Hess John; Michiels Carine; Kietzmann Thomas; Görlach Agnes
Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(4):755-61.
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2007: Görlach Agnes; Kietzmann Thomas
Superoxide and derived reactive oxygen species in the regulation of hypoxia-inducible factors.
Methods in enzymology 2007;435():421-46.
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2006: Dimova Elitsa Y; Kietzmann Thomas
The MAPK pathway and HIF-1 are involved in the induction of the human PAI-1 gene expression by insulin in the human hepatoma cell line HepG2.
Annals of the New York Academy of Sciences 2006;1090():355-67.
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2006: Petry Andreas; Djordjevic Talija; Weitnauer Michael; Kietzmann Thomas; Hess John; Görlach Agnes
NOX2 and NOX4 mediate proliferative response in endothelial cells.
Antioxidants & redox signaling 2006;8(9-10):1473-84.
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2006: Görlach Agnes; Klappa Peter; Kietzmann Thomas
The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control.
Antioxidants & redox signaling 2006;8(9-10):1391-418.
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2006: Bel Aiba Rachida S; Dimova Elitsa Y; Görlach Agnes; Kietzmann Thomas
The role of hypoxia inducible factor-1 in cell metabolism--a possible target in cancer therapy.
Expert opinion on therapeutic targets 2006;10(4):583-99.
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2006: Tron Kyrylo; Samoylenko Anatoly; Musikowski Gernot; Kobe Fritz; Immenschuh Stephan; Schaper Fred; Ramadori Giuliano; Kietzmann Thomas
Regulation of rat heme oxygenase-1 expression by interleukin-6 via the Jak/STAT pathway in hepatocytes.
Journal of hepatology 2006;45(1):72-80.
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2006: Dimova Elitsa Y; Kietzmann Thomas
Cell type-dependent regulation of the hypoxia-responsive plasminogen activator inhibitor-1 gene by upstream stimulatory factor-2.
The Journal of biological chemistry 2006;281(5):2999-3005.
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2006: Kietzmann T; Dimova E Y; Flügel D; Scharf J-G
Oxygen: modulator of physiological and pathophysiological processes in the liver.
Zeitschrift für Gastroenterologie 2006;44(1):67-76.
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2006: Petry Frauke; Ritz Vera; Meineke Cornelia; Middel Peter; Kietzmann Thomas; Schmitz-Salue Christoph; Hirsch-Ernst Karen I
Subcellular localization of rat Abca5, a rat ATP-binding-cassette transporter expressed in Leydig cells, and characterization of its splice variant apparently encoding a half-transporter.
The Biochemical journal 2006;393(Pt 1):79-87.
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2005: Scharf Jens-Gerd; Unterman Terry G; Kietzmann Thomas
Oxygen-dependent modulation of insulin-like growth factor binding protein biosynthesis in primary cultures of rat hepatocytes.
Endocrinology 2005;146(12):5433-43.
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2005: Kietzmann Thomas; Görlach Agnes
Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression.
Seminars in cell & developmental biology 2005;16(4-5):474-86.
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2005: Dimova Elitsa Y; Möller Ulrike; Herzig Stephan; Fink Trine; Zachar Vladimir; Ebbesen Peter; Kietzmann Thomas
Transcriptional regulation of plasminogen activator inhibitor-1 expression by insulin-like growth factor-1 via MAP kinases and hypoxia-inducible factor-1 in HepG2 cells.
Thrombosis and haemostasis 2005;93(6):1176-84.
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2005: Görlach Agnes; BelAiba Rachida S; Hess John; Kietzmann Thomas
Thrombin activates the p21-activated kinase in pulmonary artery smooth muscle cells. Role in tissue factor expression.
Thrombosis and haemostasis 2005;93(6):1168-75.
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2005: Wijayanti Nastiti; Kietzmann Thomas; Immenschuh Stephan
Heme oxygenase-1 gene activation by the NAD(P)H oxidase inhibitor 4-(2-aminoethyl) benzenesulfonyl fluoride via a protein kinase B, p38-dependent signaling pathway in monocytes.
The Journal of biological chemistry 2005;280(23):21820-9.
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2005: Tron Kyrylo; Novosyadlyy Ruslan; Dudas Jozsef; Samoylenko Anatoly; Kietzmann Thomas; Ramadori Giuliano
Upregulation of heme oxygenase-1 gene by turpentine oil-induced localized inflammation: involvement of interleukin-6.
Laboratory investigation; a journal of technical methods and pathology 2005;85(3):376-87.
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2004: Liu Qing; Möller Ulrike; Flügel Daniela; Kietzmann Thomas
Induction of plasminogen activator inhibitor I gene expression by intracellular calcium via hypoxia-inducible factor-1.
Blood 2004;104(13):3993-4001.
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2004: Wijayanti Nastiti; Huber Sebastian; Samoylenko Anatoly; Kietzmann Thomas; Immenschuh Stephan
Role of NF-kappaB and p38 MAP kinase signaling pathways in the lipopolysaccharide-dependent activation of heme oxygenase-1 gene expression.
Antioxidants & redox signaling 2004;6(5):802-10.
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2004: Dimova Elitsa Y; Samoylenko Anatoly; Kietzmann Thomas
Oxidative stress and hypoxia: implications for plasminogen activator inhibitor-1 expression.
Antioxidants & redox signaling 2004;6(4):777-91.
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2004: Franke Kai; Curth Katja; Lenart Jacek; Knochenhauer Doreen; Kietzmann Thomas
Enhanced plasminogen activator inhibitor-1 expression in transgenic mice with hepatocyte-specific overexpression of superoxide dismutase or glutathione peroxidase.
Antioxidants & redox signaling 2004;6(4):721-8.
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2004: BelAiba Rachida S; Djordjevic Talija; Bonello Steve; Flügel Daniela; Hess John; Kietzmann Thomas; Görlach Agnes
Redox-sensitive regulation of the HIF pathway under non-hypoxic conditions in pulmonary artery smooth muscle cells.
Biological chemistry 2004;385(3-4):249-57.
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2004: Roth Ulrike; Jungermann Kurt; Kietzmann Thomas
Modulation of glucokinase expression by hypoxia-inducible factor 1 and upstream stimulatory factor 2 in primary rat hepatocytes.
Biological chemistry 2004;385(3-4):239-47.
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2004: Liu Qing; Berchner-Pfannschmidt Utta; Möller Ulrike; Brecht Martina; Wotzlaw Christoph; Acker Helmut; Jungermann Kurt; Kietzmann Thomas
A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(12):4302-7.
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2004: Schmidt-Kastner Rainald; Aguirre-Chen Cristina; Kietzmann Thomas; Saul Isabel; Busto Raul; Ginsberg Myron D
Nuclear localization of the hypoxia-regulated pro-apoptotic protein BNIP3 after global brain ischemia in the rat hippocampus.
Brain research 2004;1001(1-2):133-42.
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2004: Knabe W; Knerlich F; Washausen S; Kietzmann T; Sirén A L; Brunnett G; Kuhn H J; Ehrenreich H
Expression patterns of erythropoietin and its receptor in the developing midbrain.
Anatomy and embryology 2004;207(6):503-12.
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2004: Roth Ulrike; Curth Katja; Unterman Terry G; Kietzmann Thomas
The transcription factors HIF-1 and HNF-4 and the coactivator p300 are involved in insulin-regulated glucokinase gene expression via the phosphatidylinositol 3-kinase/protein kinase B pathway.
The Journal of biological chemistry 2004;279(4):2623-31.
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2003: Hess Alexander; Wijayanti Nastiti; Neuschäfer-Rube Andrea Pathe; Katz Norbert; Kietzmann Thomas; Immenschuh Stephan
Phorbol ester-dependent activation of peroxiredoxin I gene expression via a protein kinase C, Ras, p38 mitogen-activated protein kinase signaling pathway.
The Journal of biological chemistry 2003;278(46):45419-34.
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2003: Görlach Agnes; Berchner-Pfannschmidt Utta; Wotzlaw Christoph; Cool Robbert H; Fandrey Joachim; Acker Helmut; Jungermann Kurt; Kietzmann Thomas
Reactive oxygen species modulate HIF-1 mediated PAI-1 expression: involvement of the GTPase Rac1.
Thrombosis and haemostasis 2003;89(5):926-35.
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2003: Kietzmann Thomas; Samoylenko Anatoly; Immenschuh Stephan
Transcriptional regulation of heme oxygenase-1 gene expression by MAP kinases of the JNK and p38 pathways in primary cultures of rat hepatocytes.
The Journal of biological chemistry 2003;278(20):17927-36.
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2003: Kietzmann Thomas; Jungermann Kurt; Görlach Agnes
Regulation of the hypoxia-dependent plasminogen activator inhibitor 1 expression by MAP kinases.
Thrombosis and haemostasis 2003;89(4):666-73.
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2003: Kietzmann Thomas; Samoylenko Anatoly; Roth Ulrike; Jungermann Kurt
Hypoxia-inducible factor-1 and hypoxia response elements mediate the induction of plasminogen activator inhibitor-1 gene expression by insulin in primary rat hepatocytes.
Blood 2003;101(3):907-14.
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2002: Görlach Agnes; Kietzmann Thomas; Hess John
Redox signaling through NADPH oxidases: involvement in vascular proliferation and coagulation.
Annals of the New York Academy of Sciences 2002;973():505-7.
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2002: Kietzmann Thomas; Krones-Herzig Anja; Jungermann Kurt
Signaling cross-talk between hypoxia and glucose via hypoxia-inducible factor 1 and glucose response elements.
Biochemical pharmacology 2002;64(5-6):903-11.
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2002: Roth Ulrike; Jungermann Kurt; Kietzmann Thomas
Activation of glucokinase gene expression by hepatic nuclear factor 4alpha in primary hepatocytes.
The Biochemical journal 2002;365(Pt 1):223-8.
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2001: Sandau K B; Zhou J; Kietzmann T; Brüne B
Regulation of the hypoxia-inducible factor 1alpha by the inflammatory mediators nitric oxide and tumor necrosis factor-alpha in contrast to desferroxamine and phenylarsine oxide.
The Journal of biological chemistry 2001;276(43):39805-11.
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2001: Kietzmann T; Knabe W; Schmidt-Kastner R
Hypoxia and hypoxia-inducible factor modulated gene expression in brain: involvement in neuroprotection and cell death.
European archives of psychiatry and clinical neuroscience 2001;251(4):170-8.
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2001: Görlach A; Diebold I; Schini-Kerth V B; Berchner-Pfannschmidt U; Roth U; Brandes R P; Kietzmann T; Busse R
Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase.
Circulation research 2001;89(1):47-54.
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2001: Krones A; Jungermann K; Kietzmann T
Cross-talk between the signals hypoxia and glucose at the glucose response element of the L-type pyruvate kinase gene.
Endocrinology 2001;142(6):2707-18.
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2001: Samoylenko A; Roth U; Jungermann K; Kietzmann T
The upstream stimulatory factor-2a inhibits plasminogen activator inhibitor-1 gene expression by binding to a promoter element adjacent to the hypoxia-inducible factor-1 binding site.
Blood 2001;97(9):2657-66.
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2001: Kietzmann T; Cornesse Y; Brechtel K; Modaressi S; Jungermann K
Perivenous expression of the mRNA of the three hypoxia-inducible factor alpha-subunits, HIF1alpha, HIF2alpha and HIF3alpha, in rat liver.
The Biochemical journal 2001;354(Pt 3):531-7.
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2000: Hirsch-Ernst K I; Kietzmann T; Ziemann C; Jungermann K; Kahl G F
Physiological oxygen tensions modulate expression of the mdr1b multidrug-resistance gene in primary rat hepatocyte cultures.
The Biochemical journal 2000;350 Pt 2():443-51.
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2000: Krones A; Kietzmann T; Jungermann K
Perivenous localization of insulin receptor protein in rat liver, and regulation of its expression by glucose and oxygen in hepatocyte cultures.
The Biochemical journal 2000;348 Pt 2():433-8.
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2000: Immenschuh S; Hinke V; Katz N; Kietzmann T
Transcriptional induction of heme oxygenase-1 gene expression by okadaic acid in primary rat hepatocyte cultures.
Molecular pharmacology 2000;57(3):610-8.
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1999: Kietzmann T; Roth U; Jungermann K
Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes.
Blood 1999;94(12):4177-85.
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1999: Kietzmann T; Hirsch-Ernst K I; Kahl G F; Jungermann K
Mimicry in primary rat hepatocyte cultures of the in vivo perivenous induction by phenobarbital of cytochrome P-450 2B1 mRNA: role of epidermal growth factor and perivenous oxygen tension.
Molecular pharmacology 1999;56(1):46-53.
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1999: Bratke J; Kietzmann T; Jungermann K
Identification of an oxygen-responsive element in the 5'-flanking sequence of the rat cytosolic phosphoenolpyruvate carboxykinase-1 gene, modulating its glucagon-dependent activation.
The Biochemical journal 1999;339 ( Pt 3)():563-9.
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1998: Kietzmann T; Porwol T; Zierold K; Jungermann K; Acker H
Involvement of a local fenton reaction in the reciprocal modulation by O2 of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene and the insulin-dependent activation of the glucokinase gene in rat hepatocytes.
The Biochemical journal 1998;335 ( Pt 2)():425-32.
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1998: Immenschuh S; Hinke V; Ohlmann A; Gifhorn-Katz S; Katz N; Jungermann K; Kietzmann T
Transcriptional activation of the haem oxygenase-1 gene by cGMP via a cAMP response element/activator protein-1 element in primary cultures of rat hepatocytes.
The Biochemical journal 1998;334 ( Pt 1)():141-6.
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1998: Immenschuh S; Kietzmann T; Hinke V; Wiederhold M; Katz N; Muller-Eberhard U
The rat heme oxygenase-1 gene is transcriptionally induced via the protein kinase A signaling pathway in rat hepatocyte cultures.
Molecular pharmacology 1998;53(3):483-91.
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1998: Krones A; Kietzmann T; Jungermann K
Periportal localization of glucagon receptor mRNA in rat liver and regulation of its expression by glucose and oxygen in hepatocyte cultures.
FEBS letters 1998;421(2):136-40.
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1997: Kietzmann T; Jungermann K
Modulation by oxygen of zonal gene expression in liver studied in primary rat hepatocyte cultures.
Cell biology and toxicology 1997;13(4-5):243-55.
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1997: Kietzmann T; Bratke J; Jungermann K
Diminution of the O2 responsiveness of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocytes by long-term culture at venous PO2.
Kidney international 1997;51(2):542-7.
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1997: Jungermann K; Kietzmann T
Role of oxygen in the zonation of carbohydrate metabolism and gene expression in liver.
Kidney international 1997;51(2):402-12.
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1997: Kietzmann T; Roth U; Freimann S; Jungermann K
Arterial oxygen partial pressures reduce the insulin-dependent induction of the perivenously located glucokinase in rat hepatocyte cultures: mimicry of arterial oxygen pressures by H2O2.
The Biochemical journal 1997;321 ( Pt 1)():17-20.
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1996: Kietzmann T; Freimann S; Bratke J; Jungermann K
Regulation of the gluconeogenic phosphoenolpyruvate carboxykinase and glycolytic aldolase A gene expression by O2 in rat hepatocyte cultures. Involvement of hydrogen peroxide as mediator in the response to O2.
FEBS letters 1996;388(2-3):228-32.
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1996: Jungermann K; Kietzmann T
Zonation of parenchymal and nonparenchymal metabolism in liver.
Annual review of nutrition 1996;16():179-203.
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1995: Kietzmann T; Immenschuh S; Katz N; Jungermann K; Muller-Eberhard U
Modulation of hemopexin gene expression by physiological oxygen tensions in primary rat hepatocyte cultures.
Biochemical and biophysical research communications 1995;213(2):397-403.
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1993: Kietzmann T; Schmidt H; Unthan-Fechner K; Probst I; Jungermann K
A ferro-heme protein senses oxygen levels, which modulate the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocyte cultures.
Biochemical and biophysical research communications 1993;195(2):792-8.
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1992: Kietzmann T; Schmidt H; Probst I; Jungermann K
Modulation of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene by oxygen in rat hepatocyte cultures. Evidence for a heme protein as oxygen sensor.
FEBS letters 1992;311(3):251-5.
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