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Shinji Kihara
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84
Funahashi, Tohru
74
Matsuzawa, Yuji
56
Shimomura, Iichiro
34
Ouchi, Noriyuki
33
Nakamura, Tadashi
33
Maeda, Norikazu
29
Nishizawa, Hitoshi
29
Yamashita, Shizuya
25
Kishida, Ken
24
Matsuda, Morihiro
22
Kuriyama, Hiroshi
19
Nishida, Makoto
18
Kumada, Masahiro
18
Okamoto, Yoshihisa
17
Nagaretani, Hiroyuki
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All Publications
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2009: Hirata Ayumu; Maeda Norikazu; Hiuge Aki; Hibuse Toshiyuki; Fujita Koichi; Okada Takuya; Kihara Shinji; Funahashi Tohru; Shimomura Iichiro
Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice.
Cardiovascular research 2009;84(1):164-72.
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2009: Fukushima Juichi; Kamada Yoshihiro; Matsumoto Hitoshi; Yoshida Yuichi; Ezaki Hisao; Takemura Takayo; Saji Yukiko; Igura Takumi; Tsutsui Shusaku; Kihara Shinji; Funahashi Tohru; Shimomura Iichiro; Tamura Shinji; Kiso Shinichi; Hayashi Norio
Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(7):724-38.
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2009: Hibuse Toshiyuki; Maeda Norikazu; Nakatsuji Hideaki; Tochino Yoshihiro; Fujita Koichi; Kihara Shinji; Funahashi Tohru; Shimomura Iichiro
The heart requires glycerol as an energy substrate through aquaporin 7, a glycerol facilitator.
Cardiovascular research 2009;83(1):34-41.
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2009: Nakagawa Yasuhiko; Kishida Ken; Kihara Shinji; Funahashi Tohru; Shimomura Iichiro
Adiponectin ameliorates hypoxia-induced pulmonary arterial remodeling.
Biochemical and biophysical research communications 2009;382(1):183-8.
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2009: Hiuge Aki; Kihara Shinji
[Human genetic mutations and polymorphisms of adipocytokines relating to obesity]
Nippon rinsho. Japanese journal of clinical medicine 2009;67(2):266-9.
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2009: Ebina Kosuke; Oshima Kazuya; Matsuda Morihiro; Fukuhara Atsunori; Maeda Kazuhisa; Kihara Shinji; Hashimoto Jun; Ochi Takahiro; Banda Nirmal K; Yoshikawa Hideki; Shimomura Iichiro
Adenovirus-mediated gene transfer of adiponectin reduces the severity of collagen-induced arthritis in mice.
Biochemical and biophysical research communications 2009;378(2):186-91.
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2009: Ezaki Hisao; Yoshida Yuichi; Saji Yukiko; Takemura Takayo; Fukushima Juichi; Matsumoto Hitoshi; Kamada Yoshihiro; Wada Akira; Igura Takumi; Kihara Shinji; Funahashi Tohru; Shimomura Iichiro; Tamura Shinji; Kiso Shinichi; Hayashi Norio
Delayed liver regeneration after partial hepatectomy in adiponectin knockout mice.
Biochemical and biophysical research communications 2009;378(1):68-72.
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2008: Nishihara Tamao; Baba Miyako; Matsuda Morihiro; Inoue Masahiro; Nishizawa Yasuko; Fukuhara Atsunori; Araki Hiroshi; Kihara Shinji; Funahashi Tohru; Tamura Shinji; Hayashi Norio; Iishi Hiroyasu; Shimomura Iichiro
Adiponectin deficiency enhances colorectal carcinogenesis and liver tumor formation induced by azoxymethane in mice.
World journal of gastroenterology : WJG 2008;14(42):6473-80.
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2008: Tsubakio-Yamamoto Kazumi; Matsuura Fumihiko; Koseki Masahiro; Oku Hiroyuki; Sandoval Jose C; Inagaki Miwako; Nakatani Kazuhiro; Nakaoka Hajime; Kawase Ryota; Yuasa-Kawase Miyako; Masuda Daisaku; Ohama Tohru; Maeda Norikazu; Nakagawa-Toyama Yumiko; Ishigami Masato; Nishida Makoto; Kihara Shinji; Shimomura Iichiro; Yamashita Shizuya
Adiponectin prevents atherosclerosis by increasing cholesterol efflux from macrophages.
Biochemical and biophysical research communications 2008;375(3):390-4.
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2008: Araki H; Nishihara T; Matsuda M; Fukuhara A; Kihara S; Funahashi T; Kataoka T R; Kamada Y; Kiyohara T; Tamura S; Hayashi N; Shimomura I
Adiponectin plays a protective role in caerulein-induced acute pancreatitis in mice fed a high-fat diet.
Gut 2008;57(10):1431-40.
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2008: Fujita Koichi; Maeda Norikazu; Sonoda Mina; Ohashi Koji; Hibuse Toshiyuki; Nishizawa Hitoshi; Nishida Makoto; Hiuge Aki; Kurata Akifumi; Kihara Shinji; Shimomura Iichiro; Funahashi Tohru
Adiponectin protects against angiotensin II-induced cardiac fibrosis through activation of PPAR-alpha.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(5):863-70.
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2008: Nakagawa Yasuhiko; Kishida Ken; Kihara Shinji; Sonoda Mina; Hirata Ayumu; Yasui Atsutaka; Nishizawa Hitoshi; Nakamura Tadashi; Yoshida Ryoko; Shimomura Iichiro; Funahashi Tohru
Nocturnal reduction in circulating adiponectin concentrations related to hypoxic stress in severe obstructive sleep apnea-hypopnea syndrome.
American journal of physiology. Endocrinology and metabolism 2008;294(4):E778-84.
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2008: Okada Takuya; Nishizawa Hitoshi; Kurata Akifumi; Tamba Sachiko; Sonoda Mina; Yasui Atsutaka; Kuroda Yohei; Hibuse Toshiyuki; Maeda Norikazu; Kihara Shinji; Hadama Tohru; Tobita Kazuki; Akamatsu Suguru; Maeda Kazuhisa; Shimomura Iichiro; Funahashi Tohru
URB is abundantly expressed in adipose tissue and dysregulated in obesity.
Biochemical and biophysical research communications 2008;367(2):370-6.
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2008: Komura Noriyuki; Kihara Shinji; Sonoda Mina; Kumada Masahiro; Fujita Koichi; Hiuge Aki; Okada Takuya; Nakagawa Yasuhiko; Tamba Sachiko; Kuroda Yohei; Hayashi Noriyuki; Sumitsuji Satoru; Kawamoto Toshiharu; Matsumoto Satoru; Ouchi Noriyuki; Arita Yukio; Okamoto Yoshihisa; Shimomura Iichiro; Funahashi Tohru; Matsuzawa Yuji;
Clinical significance of high-molecular weight form of adiponectin in male patients with coronary artery disease.
Circulation journal : official journal of the Japanese Circulation Society 2008;72(1):23-8.
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2008: Takagi Toshiyuki; Matsuda Morihiro; Abe Manabu; Kobayashi Hironori; Fukuhara Atsunori; Komuro Ryutaro; Kihara Shinji; Caslake Muriel J; McMahon Alex; Shepherd James; Funahashi Tohru; Shimomura Iichiro
Effect of pravastatin on the development of diabetes and adiponectin production.
Atherosclerosis 2008;196(1):114-21.
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2008: Tamba Sachiko; Nishizawa Hitoshi; Funahashi Tohru; Okauchi Yukiyoshi; Ogawa Tomoko; Noguchi Midori; Fujita Koichi; Ryo Miwa; Kihara Shinji; Iwahashi Hiromi; Yamagata Kazuya; Nakamura Tadashi; Shimomura Iichiro; Matsuzawa Yuji
Relationship between the serum uric acid level, visceral fat accumulation and serum adiponectin concentration in Japanese men.
Internal medicine (Tokyo, Japan) 2008;47(13):1175-80.
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2007: Yasui Atsutaka; Nishizawa Hitoshi; Okuno Yosuke; Morita Kentaro; Kobayashi Hironori; Kawai Kenichiro; Matsuda Morihiro; Kishida Ken; Kihara Shinji; Kamei Yasutomi; Ogawa Yoshihiro; Funahashi Tohru; Shimomura Iichiro
Foxo1 represses expression of musclin, a skeletal muscle-derived secretory factor.
Biochemical and biophysical research communications 2007;364(2):358-65.
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2007: Fukuhara Atsunori; Matsuda Morihiro; Nishizawa Masako; Segawa Katsumori; Tanaka Masaki; Kishimoto Kae; Matsuki Yasushi; Murakami Mirei; Ichisaka Tomoko; Murakami Hiroko; Watanabe Eijiro; Takagi Toshiyuki; Akiyoshi Megumi; Ohtsubo Tsuguteru; Kihara Shinji; Yamashita Shizuya; Makishima Makoto; Funahashi Tohru; Yamanaka Shinya; Hiramatsu Ryuji; Matsuzawa Yuji; Shimomura Iichiro
Retraction.
Science (New York, N.Y.) 2007;318(5850):565.
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2007: Oku Hiroyuki; Matsuura Fumihiko; Koseki Masahiro; Sandoval Jose C; Yuasa-Kawase Miyako; Tsubakio-Yamamoto Kazumi; Masuda Daisaku; Maeda Norikazu; Ohama Tohru; Ishigami Masato; Nishida Makoto; Hirano Ken-ichi; Kihara Shinji; Hori Masatsugu; Shimomura Iichiro; Yamashita Shizuya
Adiponectin deficiency suppresses ABCA1 expression and ApoA-I synthesis in the liver.
FEBS letters 2007;581(26):5029-33.
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2007: Kamada Yoshihiro; Matsumoto Hitoshi; Tamura Shinji; Fukushima Juichi; Kiso Shinichi; Fukui Koji; Igura Takumi; Maeda Norikazu; Kihara Shinji; Funahashi Tohru; Matsuzawa Yuji; Shimomura Iichiro; Hayashi Norio
Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model.
Journal of hepatology 2007;47(4):556-64.
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2007: Ohashi Koji; Iwatani Hirotsugu; Kihara Shinji; Nakagawa Yasuhiko; Komura Noriyuki; Fujita Koichi; Maeda Norikazu; Nishida Makoto; Katsube Fumie; Shimomura Iichiro; Ito Takahito; Funahashi Tohru
Exacerbation of albuminuria and renal fibrosis in subtotal renal ablation model of adiponectin-knockout mice.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(9):1910-7.
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2007: Okauchi Yukiyoshi; Nishizawa Hitoshi; Funahashi Tohru; Ogawa Tomoko; Noguchi Midori; Ryo Miwa; Kihara Shinji; Iwahashi Hiromi; Yamagata Kazuya; Nakamura Tadashi; Shimomura Iichiro; Matsuzawa Yuji
Reduction of visceral fat is associated with decrease in the number of metabolic risk factors in Japanese men.
Diabetes care 2007;30(9):2392-4.
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2007: Matsuura Fumihiko; Oku Hiroyuki; Koseki Masahiro; Sandoval Jose C; Yuasa-Kawase Miyako; Tsubakio-Yamamoto Kazumi; Masuda Daisaku; Maeda Norikazu; Tsujii Ken-ichi; Ishigami Masato; Nishida Makoto; Hirano Ken-ichi; Kihara Shinji; Hori Masatsugu; Shimomura Iichiro; Yamashita Shizuya
Adiponectin accelerates reverse cholesterol transport by increasing high density lipoprotein assembly in the liver.
Biochemical and biophysical research communications 2007;358(4):1091-5.
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2007: Tanida Mamoru; Shen Jiao; Horii Yuko; Matsuda Morihiro; Kihara Shinji; Funahashi Toru; Shimomura Iichiro; Sawai Hajime; Fukuda Yutaka; Matsuzawa Yuji; Nagai Katsuya
Effects of adiponectin on the renal sympathetic nerve activity and blood pressure in rats.
Experimental biology and medicine (Maywood, N.J.) 2007;232(3):390-7.
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2007: Hiuge Aki; Tenenbaum Alexander; Maeda Norikazu; Benderly Michal; Kumada Masahiro; Fisman Enrique Z; Tanne David; Matas Zipora; Hibuse Toshiyuki; Fujita Koichi; Nishizawa Hitoshi; Adler Yehuda; Motro Michael; Kihara Shinji; Shimomura Iichiro; Behar Solomon; Funahashi Tohru
Effects of peroxisome proliferator-activated receptor ligands, bezafibrate and fenofibrate, on adiponectin level.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(3):635-41.
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2006: Iwashima Yoshio; Horio Takeshi; Kumada Masahiro; Suzuki Yoshihiko; Kihara Shinji; Rakugi Hiromi; Kawano Yuhei; Funahashi Tohru; Ogihara Toshio
Adiponectin and renal function, and implication as a risk of cardiovascular disease.
The American journal of cardiology 2006;98(12):1603-8.
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2006: Kurata A; Nishizawa H; Kihara S; Maeda N; Sonoda M; Okada T; Ohashi K; Hibuse T; Fujita K; Yasui A; Hiuge A; Kumada M; Kuriyama H; Shimomura I; Funahashi T
Blockade of Angiotensin II type-1 receptor reduces oxidative stress in adipose tissue and ameliorates adipocytokine dysregulation.
Kidney international 2006;70(10):1717-24.
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2006: Segawa Katsumori; Fukuhara Atsunori; Hosogai Naomi; Morita Kentaro; Okuno Yosuke; Tanaka Masaki; Nakagawa Yasuhiko; Kihara Shinji; Funahashi Tohru; Komuro Ryutaro; Matsuda Morihiro; Shimomura Iichiro
Visfatin in adipocytes is upregulated by hypoxia through HIF1alpha-dependent mechanism.
Biochemical and biophysical research communications 2006;349(3):875-82.
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2006: Iwashima Yoshio; Horio Takeshi; Suzuki Yoshihiko; Kihara Shinji; Rakugi Hiromi; Kangawa Kenji; Funahashi Tohru; Ogihara Toshio; Kawano Yuhei
Adiponectin and inflammatory markers in peripheral arterial occlusive disease.
Atherosclerosis 2006;188(2):384-90.
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2006: Nishihara Tamao; Matsuda Morihiro; Araki Hiroshi; Oshima Kazuya; Kihara Shinji; Funahashi Tohru; Shimomura Iichiro
Effect of adiponectin on murine colitis induced by dextran sulfate sodium.
Gastroenterology 2006;131(3):853-61.
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2006: Matsumoto Hitoshi; Tamura Shinji; Kamada Yoshihiro; Kiso Shinichi; Fukushima Juichi; Wada Akira; Maeda Norikazu; Kihara Shinji; Funahashi Tohru; Matsuzawa Yuji; Shimomura Iichiro; Hayashi Norio
Adiponectin deficiency exacerbates lipopolysaccharide/D-galactosamine-induced liver injury in mice.
World journal of gastroenterology : WJG 2006;12(21):3352-8.
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2006: Ohashi Koji; Kihara Shinji; Ouchi Noriyuki; Kumada Masahiro; Fujita Koichi; Hiuge Aki; Hibuse Toshiyuki; Ryo Miwa; Nishizawa Hitoshi; Maeda Norikazu; Maeda Kazuhisa; Shibata Rei; Walsh Kenneth; Funahashi Tohru; Shimomura Iichiro
Adiponectin replenishment ameliorates obesity-related hypertension.
Hypertension 2006;47(6):1108-16.
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2006: Ujiie Hidetoshi; Oritani Kenji; Kato Hisashi; Yokota Takafumi; Takahashi Isao; Maeda Tetsuo; Masaie Hiroaki; Ichii Michiko; Kamada Yoshihiro; Tamura Shinji; Kihara Shinji; Funahashi Tohru; Tomiyama Yoshiaki; Kanakura Yuzuru
Identification of amino-terminal region of adiponectin as a physiologically functional domain.
Journal of cellular biochemistry 2006;98(1):194-207.
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2006: Okamoto Yoshihisa; Kihara Shinji; Funahashi Tohru; Matsuzawa Yuji; Libby Peter
Adiponectin: a key adipocytokine in metabolic syndrome.
Clinical science (London, England : 1979) 2006;110(3):267-78.
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2005: Hibuse Toshiyuki; Maeda Norikazu; Funahashi Tohru; Yamamoto Kaori; Nagasawa Azumi; Mizunoya Wataru; Kishida Ken; Inoue Kazuo; Kuriyama Hiroshi; Nakamura Tadashi; Fushiki Tohru; Kihara Shinji; Shimomura Iichiro
Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(31):10993-8.
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2005: Horio Takeshi; Suzuki Masaaki; Suzuki Kazutaka; Takamisawa Itaru; Hiuge Aki; Kamide Kei; Takiuchi Shin; Iwashima Yoshio; Kihara Shinji; Funahashi Tohru; Yoshimasa Yasunao; Kawano Yuhei
Pioglitazone improves left ventricular diastolic function in patients with essential hypertension.
American journal of hypertension 2005;18(7):949-57.
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2005: Iwashima Yoshio; Katsuya Tomohiro; Ishikawa Kazuhiko; Kida Iwao; Ohishi Mitsuru; Horio Takeshi; Ouchi Noriyuki; Ohashi Koji; Kihara Shinji; Funahashi Tohru; Rakugi Hiromi; Ogihara Toshio
Association of hypoadiponectinemia with smoking habit in men.
Hypertension 2005;45(6):1094-100.
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2005: Yamamoto K; Kiyohara T; Murayama Y; Kihara S; Okamoto Y; Funahashi T; Ito T; Nezu R; Tsutsui S; Miyagawa J-I; Tamura S; Matsuzawa Y; Shimomura I; Shinomura Y
Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn's disease.
Gut 2005;54(6):789-96.
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2005: Fukuhara Atsunori; Matsuda Morihiro; Nishizawa Masako; Segawa Katsumori; Tanaka Masaki; Kishimoto Kae; Matsuki Yasushi; Murakami Mirei; Ichisaka Tomoko; Murakami Hiroko; Watanabe Eijiro; Takagi Toshiyuki; Akiyoshi Megumi; Ohtsubo Tsuguteru; Kihara Shinji; Yamashita Shizuya; Makishima Makoto; Funahashi Tohru; Yamanaka Shinya; Hiramatsu Ryuji; Matsuzawa Yuji; Shimomura Iichiro
Visfatin: a protein secreted by visceral fat that mimics the effects of insulin.
Science (New York, N.Y.) 2005;307(5708):426-30.
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2004: Maeda Norikazu; Funahashi Tohru; Hibuse Toshiyuki; Nagasawa Azumi; Kishida Ken; Kuriyama Hiroshi; Nakamura Tadashi; Kihara Shinji; Shimomura Iichiro; Matsuzawa Yuji
Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(51):17801-6.
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2004: Ryo Miwa; Nakamura Tadashi; Kihara Shinji; Kumada Masahiro; Shibazaki Satomi; Takahashi Mihoko; Nagai Masaki; Matsuzawa Yuji; Funahashi Tohru
Adiponectin as a biomarker of the metabolic syndrome.
Circulation journal : official journal of the Japanese Circulation Society 2004;68(11):975-81.
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2004: Iwashima Yoshio; Katsuya Tomohiro; Ishikawa Kazuhiko; Ouchi Noriyuki; Ohishi Mitsuru; Sugimoto Ken; Fu Yuxiao; Motone Masaharu; Yamamoto Kouichi; Matsuo Akiko; Ohashi Koji; Kihara Shinji; Funahashi Tohru; Rakugi Hiromi; Matsuzawa Yuji; Ogihara Toshio
Hypoadiponectinemia is an independent risk factor for hypertension.
Hypertension 2004;43(6):1318-23.
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2004: Kumada Masahiro; Kihara Shinji; Ouchi Noriyuki; Kobayashi Hideki; Okamoto Yoshihisa; Ohashi Koji; Maeda Kazuhisa; Nagaretani Hiroyuki; Kishida Ken; Maeda Norikazu; Nagasawa Azumi; Funahashi Tohru; Matsuzawa Yuji
Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages.
Circulation 2004;109(17):2046-9.
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2004: Ohashi Koji; Ouchi Noriyuki; Kihara Shinji; Funahashi Tohru; Nakamura Tadashi; Sumitsuji Satoru; Kawamoto Toshiharu; Matsumoto Satoru; Nagaretani Hiroyuki; Kumada Masahiro; Okamoto Yoshihisa; Nishizawa Hitoshi; Kishida Ken; Maeda Norikazu; Hiraoka Hisatoyo; Iwashima Yoshio; Ishikawa Kazuhiko; Ohishi Mitsuru; Katsuya Tomohiro; Rakugi Hiromi; Ogihara Toshio; Matsuzawa Yuji
Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease.
Journal of the American College of Cardiology 2004;43(7):1195-200.
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2004: Kumada Masahiro; Kihara Shinji; Funahashi Tohru; Matsuzawa Yuji
[High sensitivity C-reactive protein analysis in th diagnosis of arteriosclerosis]
Nippon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 3():292-5.
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2004: Kobayashi Hideki; Ouchi Noriyuki; Kihara Shinji; Walsh Kenneth; Kumada Masahiro; Abe Yuki; Funahashi Tohru; Matsuzawa Yuji
Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin.
Circulation research 2004;94(4):e27-31.
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2004: Matsuzawa Yuji; Funahashi Tohru; Kihara Shinji; Shimomura Iichiro
Adiponectin and metabolic syndrome.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(1):29-33.
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2003: Kamada Yoshihiro; Tamura Shinji; Kiso Shinichi; Matsumoto Hitoshi; Saji Yukiko; Yoshida Yuichi; Fukui Koji; Maeda Norikazu; Nishizawa Hitoshi; Nagaretani Hiroyuki; Okamoto Yoshihisa; Kihara Shinji; Miyagawa Jun-Ichiro; Shinomura Yasuhisa; Funahashi Tohru; Matsuzawa Yuji
Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin.
Gastroenterology 2003;125(6):1796-807.
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2003: Ouchi Noriyuki; Kihara Shinji; Funahashi Tohru; Matsuzawa Yuji; Walsh Kenneth
Obesity, adiponectin and vascular inflammatory disease.
Current opinion in lipidology 2003;14(6):561-6.
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2003: Miyoshi Yasuo; Funahashi Tohru; Kihara Shinji; Taguchi Tetsuya; Tamaki Yasuhiro; Matsuzawa Yuji; Noguchi Shinzaburo
Association of serum adiponectin levels with breast cancer risk.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5699-704.
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2003: Nagasawa Azumi; Fukui Kensuke; Kojima Makiko; Kishida Ken; Maeda Norikazu; Nagaretani Hiroyuki; Hibuse Toshiyuki; Nishizawa Hitoshi; Kihara Shinji; Waki Masako; Takamatsu Kiyoharu; Funahashi Tohru; Matsuzawa Yuji
Divergent effects of soy protein diet on the expression of adipocytokines.
Biochemical and biophysical research communications 2003;311(4):909-14.
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2003: Ouchi Noriyuki; Ohishi Mitsuru; Kihara Shinji; Funahashi Tohru; Nakamura Tadashi; Nagaretani Hiroyuki; Kumada Masahiro; Ohashi Koji; Okamoto Yoshihisa; Nishizawa Hitoshi; Kishida Ken; Maeda Norikazu; Nagasawa Azumi; Kobayashi Hideki; Hiraoka Hisatoyo; Komai Norio; Kaibe Masaharu; Rakugi Hiromi; Ogihara Toshio; Matsuzawa Yuji
Association of hypoadiponectinemia with impaired vasoreactivity.
Hypertension 2003;42(3):231-4.
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2003: Kishida Ken; Nagaretani Hiroyuki; Kondo Hidehiko; Kobayashi Hideki; Tanaka Sachiyo; Maeda Norikazu; Nagasawa Azumi; Hibuse Toshiyuki; Ohashi Koji; Kumada Masahiro; Nishizawa Hitoshi; Okamoto Yoshihisa; Ouchi Noriyuki; Maeda Kazuhisa; Kihara Shinji; Funahashi Tohru; Matsuzawa Yuji
Disturbed secretion of mutant adiponectin associated with the metabolic syndrome.
Biochemical and biophysical research communications 2003;306(1):286-92.
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2003: Sakai Naohiko; Uchida Yoshiaki; Ohashi Koji; Hibuse Toshiyuki; Saika Yasuhiko; Tomari Yoshiaki; Kihara Shinji; Hiraoka Hisatoyo; Nakamura Tadashi; Ito Satoru; Yamashita Shizuya; Matsuzawa Yuji
Measurement of fasting serum apoB-48 levels in normolipidemic and hyperlipidemic subjects by ELISA.
Journal of lipid research 2003;44(6):1256-62.
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2003: Saika Y; Sakai N; Takahashi M; Maruyama T; Kihara S; Ouchi N; Ishigami M; Hiraoka H; Nakamura T; Yamashita S; Matsuzawa Y
Novel LPL mutation (L303F) found in a patient associated with coronary artery disease and severe systemic atherosclerosis.
European journal of clinical investigation 2003;33(3):216-22.
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2003: Ouchi Noriyuki; Kihara Shinji; Funahashi Tohru; Nakamura Tadashi; Nishida Makoto; Kumada Masahiro; Okamoto Yoshihisa; Ohashi Koji; Nagaretani Hiroyuki; Kishida Ken; Nishizawa Hitoshi; Maeda Norikazu; Kobayashi Hideki; Hiraoka Hisatoyo; Matsuzawa Yuji
Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue.
Circulation 2003;107(5):671-4.
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2003: Kumada Masahiro; Kihara Shinji; Sumitsuji Satoru; Kawamoto Toshiharu; Matsumoto Satoru; Ouchi Noriyuki; Arita Yukio; Okamoto Yoshihisa; Shimomura Iichiro; Hiraoka Hisatoyo; Nakamura Tadashi; Funahashi Tohru; Matsuzawa Yuji;
Association of hypoadiponectinemia with coronary artery disease in men.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(1):85-9.
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2003: Matsuzawa Yuji; Shimomura Iichiro; Kihara Shinji; Funahashi Tohru
Importance of adipocytokines in obesity-related diseases.
Hormone research 2003;60 Suppl 3():56-9.
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2002: Nagasawa A; Fukui K; Funahashi T; Maeda N; Shimomura I; Kihara S; Waki M; Takamatsu K; Matsuzawa Y
Effects of soy protein diet on the expression of adipose genes and plasma adiponectin.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(11-12):635-9.
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2002: Okamoto Yoshihisa; Kihara Shinji; Ouchi Noriyuki; Nishida Makoto; Arita Yukio; Kumada Masahiro; Ohashi Koji; Sakai Naohiko; Shimomura Iichiro; Kobayashi Hideki; Terasaka Naoki; Inaba Toshimori; Funahashi Tohru; Matsuzawa Yuji
Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice.
Circulation 2002;106(22):2767-70.
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2002: Kuriyama Hiroshi; Shimomura Iichiro; Kishida Ken; Kondo Hidehiko; Furuyama Naoki; Nishizawa Hitoshi; Maeda Norikazu; Matsuda Morihiro; Nagaretani Hiroyuki; Kihara Shinji; Nakamura Tadashi; Tochino Yoshihiro; Funahashi Tohru; Matsuzawa Yuji
Coordinated regulation of fat-specific and liver-specific glycerol channels, aquaporin adipose and aquaporin 9.
Diabetes 2002;51(10):2915-21.
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2002: Matsuda Morihiro; Shimomura Iichiro; Sata Masataka; Arita Yukio; Nishida Makoto; Maeda Norikazu; Kumada Masahiro; Okamoto Yoshihisa; Nagaretani Hiroyuki; Nishizawa Hitoshi; Kishida Ken; Komuro Ryutaro; Ouchi Noriyuki; Kihara Shinji; Nagai Ryozo; Funahashi Tohru; Matsuzawa Yuji
Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis.
The Journal of biological chemistry 2002;277(40):37487-91.
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2002: Nishizawa Hitoshi; Shimomura Iichiro; Kishida Ken; Maeda Norikazu; Kuriyama Hiroshi; Nagaretani Hiroyuki; Matsuda Morihiro; Kondo Hidehiko; Furuyama Naoki; Kihara Shinji; Nakamura Tadashi; Tochino Yoshihiro; Funahashi Tohru; Matsuzawa Yuji
Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein.
Diabetes 2002;51(9):2734-41.
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2002: Kondo Hidehiko; Shimomura Iichiro; Matsukawa Yuko; Kumada Masahiro; Takahashi Masahiko; Matsuda Morihiro; Ouchi Noriyuki; Kihara Shinji; Kawamoto Toshiharu; Sumitsuji Satoru; Funahashi Tohru; Matsuzawa Yuji
Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome.
Diabetes 2002;51(7):2325-8.
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2002: Maeda Norikazu; Shimomura Iichiro; Kishida Ken; Nishizawa Hitoshi; Matsuda Morihiro; Nagaretani Hiroyuki; Furuyama Naoki; Kondo Hidehiko; Takahashi Masahiko; Arita Yukio; Komuro Ryutaro; Ouchi Noriyuki; Kihara Shinji; Tochino Yoshihiro; Okutomi Keiichi; Horie Masato; Takeda Satoshi; Aoyama Toshifumi; Funahashi Tohru; Matsuzawa Yuji
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30.
Nature medicine 2002;8(7):731-7.
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2002: Arita Yukio; Kihara Shinji; Ouchi Noriyuki; Maeda Kazuhisa; Kuriyama Hiroshi; Okamoto Yoshihisa; Kumada Masahiro; Hotta Kikuko; Nishida Makoto; Takahashi Masahiko; Nakamura Tadashi; Shimomura Iichiro; Muraguchi Masahiro; Ohmoto Yasukazu; Funahashi Tohru; Matsuzawa Yuji
Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell.
Circulation 2002;105(24):2893-8.
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2002: Kondo Hidehiko; Shimomura Iichiro; Kishida Ken; Kuriyama Hiroshi; Makino Yasunaka; Nishizawa Hitoshi; Matsuda Morihiro; Maeda Norikazu; Nagaretani Hiroyuki; Kihara Shinji; Kurachi Yoshihisa; Nakamura Tadashi; Funahashi Tohru; Matsuzawa Yuji
Human aquaporin adipose (AQPap) gene. Genomic structure, promoter analysis and functional mutation.
European journal of biochemistry / FEBS 2002;269(7):1814-26.
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2002: Matsumoto Satoru; Kishida Ken; Shimomura Iichiro; Maeda Norikazu; Nagaretani Hiroyuki; Matsuda Morihiro; Nishizawa Hitoshi; Kihara Shinji; Funahashi Tohru; Matsuzawa Yuji; Yamada A; Yamashita S; Tamura S; Kawata S
Increased plasma HB-EGF associated with obesity and coronary artery disease.
Biochemical and biophysical research communications 2002;292(3):781-6.
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2002: Nishizawa Hitoshi; Yamagata Kazuya; Shimomura Iichiro; Takahashi Masahiko; Kuriyama Hiroshi; Kishida Ken; Hotta Kikuko; Nagaretani Hiroyuki; Maeda Norikazu; Matsuda Morihiro; Kihara Shinji; Nakamura Tadashi; Nishigori Hidekazu; Tomura Hideaki; Moore David D; Takeda Jun; Funahashi Tohru; Matsuzawa Yuji
Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation.
The Journal of biological chemistry 2002;277(2):1586-92.
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2001: Nakamura T; Funahashi T; Yamashita S; Nishida M; Nishida Y; Takahashi M; Hotta K; Kuriyama H; Kihara S; Ohuchi N; Nishimura T; Kishino B I; Ishikawa K; Kawamoto T; Tokunaga K; Nakagawa C; Mineo I; Watanabe F; Tarui S; Matsuzawa Y
Thiazolidinedione derivative improves fat distribution and multiple risk factors in subjects with visceral fat accumulation--double-blind placebo-controlled trial.
Diabetes research and clinical practice 2001;54(3):181-90.
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2001: Kishida K; Shimomura I; Nishizawa H; Maeda N; Kuriyama H; Kondo H; Matsuda M; Nagaretani H; Ouchi N; Hotta K; Kihara S; Kadowaki T; Funahashi T; Matsuzawa Y
Enhancement of the aquaporin adipose gene expression by a peroxisome proliferator-activated receptor gamma.
The Journal of biological chemistry 2001;276(51):48572-9.
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2001: Maeda N; Takahashi M; Funahashi T; Kihara S; Nishizawa H; Kishida K; Nagaretani H; Matsuda M; Komuro R; Ouchi N; Kuriyama H; Hotta K; Nakamura T; Shimomura I; Matsuzawa Y
PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein.
Diabetes 2001;50(9):2094-9.
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2001: Kishida K; Shimomura I; Kondo H; Kuriyama H; Makino Y; Nishizawa H; Maeda N; Matsuda M; Ouchi N; Kihara S; Kurachi Y; Funahashi T; Matsuzawa Y
Genomic structure and insulin-mediated repression of the aquaporin adipose (AQPap), adipose-specific glycerol channel.
The Journal of biological chemistry 2001;276(39):36251-60.
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2001: Hotta K; Funahashi T; Matsukawa Y; Takahashi M; Nishizawa H; Kishida K; Matsuda M; Kuriyama H; Kihara S; Nakamura T; Tochino Y; Bodkin N L; Hansen B C; Matsuzawa Y
Galectin-12, an Adipose-expressed Galectin-like Molecule Possessing Apoptosis-inducing Activity.
The Journal of biological chemistry 2001;276(36):34089-97.
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2001: Takahashi M; Nagaretani H; Funahashi T; Nishizawa H; Maeda N; Kishida K; Kuriyama H; Shimomura I; Maeda K; Hotta K; Ouchi N; Kihara S; Nakamura T; Yamashita S; Matsuzawa Y
The expression of SPARC in adipose tissue and its increased plasma concentration in patients with coronary artery disease.
Obesity research 2001;9(7):388-93.
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2001: Tamura R; Miyagawa J; Nishida M; Kihara S; Sasada R; Igarashi K; Nakata A; Yamamori K; Kameda-Takemura K; Yamashita S; Matsuzawa Y
Immunohistochemical localization of Betacellulin, a member of epidermal growth factor family, in atherosclerotic plaques of human aorta.
Atherosclerosis 2001;155(2):413-23.
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2001: Kihara S
[Autoimmune hyperlipidemia]
Nippon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 3():119-23.
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2001: Ouchi N; Kihara S; Arita Y; Nishida M; Matsuyama A; Okamoto Y; Ishigami M; Kuriyama H; Kishida K; Nishizawa H; Hotta K; Muraguchi M; Ohmoto Y; Yamashita S; Funahashi T; Matsuzawa Y
Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages.
Circulation 2001;103(8):1057-63.
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2000: Ouchi N; Kihara S; Arita Y; Okamoto Y; Maeda K; Kuriyama H; Hotta K; Nishida M; Takahashi M; Muraguchi M; Ohmoto Y; Nakamura T; Yamashita S; Funahashi T; Matsuzawa Y
Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway.
Circulation 2000;102(11):1296-301.
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2000: Yokota T; Oritani K; Takahashi I; Ishikawa J; Matsuyama A; Ouchi N; Kihara S; Funahashi T; Tenner A J; Tomiyama Y; Matsuzawa Y
Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages.
Blood 2000;96(5):1723-32.
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2000: Takahashi M; Arita Y; Yamagata K; Matsukawa Y; Okutomi K; Horie M; Shimomura I; Hotta K; Kuriyama H; Kihara S; Nakamura T; Yamashita S; Funahashi T; Matsuzawa Y
Genomic structure and mutations in adipose-specific gene, adiponectin.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24(7):861-8.
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2000: Kishida K; Kuriyama H; Funahashi T; Shimomura I; Kihara S; Ouchi N; Nishida M; Nishizawa H; Matsuda M; Takahashi M; Hotta K; Nakamura T; Yamashita S; Tochino Y; Matsuzawa Y
Aquaporin adipose, a putative glycerol channel in adipocytes.
The Journal of biological chemistry 2000;275(27):20896-902.
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2000: Matsuyama A; Yamashita S; Sakai N; Maruyama T; Okuda E; Hirano K; Kihara S; Hiraoka H; Matsuzawa Y
Identification of a GPI-anchored type HDL-binding protein on human macrophages.
Biochemical and biophysical research communications 2000;272(3):864-71.
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2000: Hotta K; Funahashi T; Arita Y; Takahashi M; Matsuda M; Okamoto Y; Iwahashi H; Kuriyama H; Ouchi N; Maeda K; Nishida M; Kihara S; Sakai N; Nakajima T; Hasegawa K; Muraguchi M; Ohmoto Y; Nakamura T; Yamashita S; Hanafusa T; Matsuzawa Y
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(6):1595-9.
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2000: Nishida M; Miyagawa J; Yamashita S; Higashiyama S; Nakata A; Ouchi N; Tamura R; Yamamori K; Kihara S; Taniguchi N; Matsuzawa Y
Localization of CD9, an enhancer protein for proheparin-binding epidermal growth factor-like growth factor, in human atherosclerotic plaques: possible involvement of juxtacrine growth mechanism on smooth muscle cell proliferation.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(5):1236-43.
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2000: Okamoto Y; Arita Y; Nishida M; Muraguchi M; Ouchi N; Takahashi M; Igura T; Inui Y; Kihara S; Nakamura T; Yamashita S; Miyagawa J; Funahashi T; Matsuzawa Y
An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2000;32(2):47-50.
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1999: Ouchi N; Kihara S; Arita Y; Maeda K; Kuriyama H; Okamoto Y; Hotta K; Nishida M; Takahashi M; Nakamura T; Yamashita S; Funahashi T; Matsuzawa Y
Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin.
Circulation 1999;100(25):2473-6.
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1999: Arita Y; Kihara S; Ouchi N; Takahashi M; Maeda K; Miyagawa J; Hotta K; Shimomura I; Nakamura T; Miyaoka K; Kuriyama H; Nishida M; Yamashita S; Okubo K; Matsubara K; Muraguchi M; Ohmoto Y; Funahashi T; Matsuzawa Y
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity.
Biochemical and biophysical research communications 1999;257(1):79-83.
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1999: Funahashi T; Nakamura T; Shimomura I; Maeda K; Kuriyama H; Takahashi M; Arita Y; Kihara S; Matsuzawa Y
Role of adipocytokines on the pathogenesis of atherosclerosis in visceral obesity.
Internal medicine (Tokyo, Japan) 1999;38(2):202-6.
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1998: Takami S; Yamashita S; Kihara S; Kameda-Takemura K; Matsuzawa Y
High concentration of glucose induces the expression of intercellular adhesion molecule-1 in human umbilical vein endothelial cells.
Atherosclerosis 1998;138(1):35-41.
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1998: Takami S; Yamashita S; Kihara S; Ishigami M; Takemura K; Kume N; Kita T; Matsuzawa Y
Lipoprotein(a) enhances the expression of intercellular adhesion molecule-1 in cultured human umbilical vein endothelial cells.
Circulation 1998;97(8):721-8.
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1998: Shinohara E; Kihara S; Ouchi N; Funahashi T; Nakamura T; Yamashita S; Kameda-Takemura K; Matsuzawa Y
Troglitazone suppresses intimal formation following balloon injury in insulin-resistant Zucker fatty rats.
Atherosclerosis 1998;136(2):275-9.
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1998: Kihara S; Ouchi N; Funahashi T; Shinohara E; Tamura R; Yamashita S; Matsuzawa Y
Troglitazone enhances glucose uptake and inhibits mitogen-activated protein kinase in human aortic smooth muscle cells.
Atherosclerosis 1998;136(1):163-8.
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1998: Kihara S
[Lipoprotein lipase inhibitory factor]
Ryoikibetsu shokogun shirizu 1998;(19 Pt 2):88-90.
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1997: Ouchi N; Kihara S; Yamashita S; Higashiyama S; Nakagawa T; Shimomura I; Funahashi T; Kameda-Takemura K; Kawata S; Taniguchi N; Matsuzawa Y
Role of membrane-anchored heparin-binding epidermal growth factor-like growth factor and CD9 on macrophages.
The Biochemical journal 1997;328 ( Pt 3)():923-8.
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1997: Yanagi K; Yamashita S; Kihara S; Nakamura T; Nozaki S; Nagai Y; Funahashi T; Kameda-Takemura K; Ueyama Y; Jiao S; Kubo M; Tokunaga K; Matsuzawa Y
Characteristics of coronary artery disease and lipoprotein abnormalities in patients with heterozygous familial hypercholesterolemia associated with diabetes mellitus or impaired glucose tolerance.
Atherosclerosis 1997;132(1):43-51.
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1997: Nakamura T; Kobayashi H; Yanagi K; Nakagawa T; Nishida M; Kihara S; Hiraoka H; Nozaki S; Funahashi T; Yamashita S; Kameda-Takemura K; Matsuzawa Y
Importance of intra-abdominal visceral fat accumulation to coronary atherosclerosis in heterozygous familial hypercholesterolaemia.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1997;21(7):580-6.
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1997: Shinohara E; Yamashita S; Kihara S; Hirano K; Ishigami M; Arai T; Nozaki S; Kameda-Takemura K; Kawata S; Matsuzawa Y
Interferon alpha induces disorder of lipid metabolism by lowering postheparin lipases and cholesteryl ester transfer protein activities in patients with chronic hepatitis C.
Hepatology (Baltimore, Md.) 1997;25(6):1502-6.
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1997: Yanagi K; Yamashita S; Hiraoka H; Ishigami M; Kihara S; Hirano K; Sakai N; Nozaki S; Funahashi T; Kameda-Takemura K; Kubo M; Tokunaga K; Matsuzawa Y
Increased serum remnant lipoproteins in patients with apolipoprotein E7 (apo E Suita).
Atherosclerosis 1997;131(1):49-58.
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1997: Shinohara E; Kihara S; Yamashita S; Yamane M; Nishida M; Arai T; Kotani K; Nakamura T; Takemura K; Matsuzawa Y
Visceral fat accumulation as an important risk factor for obstructive sleep apnoea syndrome in obese subjects.
Journal of internal medicine 1997;241(1):11-8.
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1995: Hirano K; Yamashita S; Kuga Y; Sakai N; Nozaki S; Kihara S; Arai T; Yanagi K; Takami S; Menju M
Atherosclerotic disease in marked hyperalphalipoproteinemia. Combined reduction of cholesteryl ester transfer protein and hepatic triglyceride lipase.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(11):1849-56.
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1995: Yamane M; Jiao S; Kihara S; Shimomura I; Yanagi K; Tokunaga K; Kawata S; Odaka H; Ikeda H; Yamashita S
Increased proportion of plasma apoB-48 to apoB-100 in non-insulin-dependent diabetic rats: contribution of enhanced apoB mRNA editing in the liver.
Journal of lipid research 1995;36(8):1676-85.
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1990: Kihara S; Matsuzawa Y
[Hematological disorder and hyperlipoproteinemia]
Nippon rinsho. Japanese journal of clinical medicine 1990;48(11):2593-8.
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1990: Matsuzawa Y; Kihara S; Kubo M; Tarui S
[Autoimmune chylomicronemia--pathogenesis and pathophysiology]
Nippon rinsho. Japanese journal of clinical medicine 1990;48(6):1344-50.
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1989: Kihara S; Matsuzawa Y; Kubo M; Nozaki S; Funahashi T; Yamashita S; Sho N; Tarui S
Autoimmune hyperchylomicronemia.
The New England journal of medicine 1989;320(19):1255-9.
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1989: Kihara S; Kubo M; Ikeda N; Yokoyama S; Matsuzawa Y; Tarui S; Yamamoto A; Hostetler K Y
Inhibition of purified human postheparin lipoprotein lipase by beta-adrenergic blockers in vitro.
Biochemical pharmacology 1989;38(3):407-11.
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1988: Matsubara K; Matsuzawa Y; Jiao S; Kihara S; Takama T; Nakamura T; Tokunaga K; Kubo M; Tarui S
Cholesterol-lowering effect of N-(alpha-methylbenzyl)linoleamide (melinamide) in cholesterol-fed diabetic rats.
Atherosclerosis 1988;72(2-3):199-204.
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1988: Jiao S; Matsuzawa Y; Matsubara K; Kihara S; Nakamura T; Tokunaga K; Kubo M; Tarui S
Increased activity of intestinal acyl-CoA: cholesterol acyltransferase in rats with streptozocin-induced diabetes and restoration by insulin supplementation.
Diabetes 1988;37(3):342-6.
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