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Ushio Kikkawa

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Akio Nakashima; Noriko Oshiro; Ken-Ichi Yoshino; Eugene Hsin Yu; Sumiko Eguchi; Satoshi Eguchi; Ippei Kawanishi; Ushio Kikkawa; Kazuyoshi Yonezawa
Association of CAD, a multifunctional protein involved in pyrimidine synthesis, with mLST8, a component of the mTOR complexes.
Taiki Nagano; Akio Nakashima; Toshiaki Hashimoto; Ushio Kikkawa; Shinji Kamada
X-linked inhibitor of apoptosis protein mediates neddylation by itself but does not function as a NEDD8-E3 ligase for caspase-7.
Toshiaki Hashimoto; Ushio Kikkawa; Shinji Kamada
Contribution of caspase(s) to the cell cycle regulation at mitotic phase.

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2013: Akio Nakashima; Noriko Oshiro; Ken-Ichi Yoshino; Eugene Hsin Yu; Sumiko Eguchi; Satoshi Eguchi; Ippei Kawanishi; Ushio Kikkawa; Kazuyoshi Yonezawa
Association of CAD, a multifunctional protein involved in pyrimidine synthesis, with mLST8, a component of the mTOR complexes.
Journal of biomedical science 2013;20(1):24.
2012: Taiki Nagano; Akio Nakashima; Toshiaki Hashimoto; Ushio Kikkawa; Shinji Kamada
X-linked inhibitor of apoptosis protein mediates neddylation by itself but does not function as a NEDD8-E3 ligase for caspase-7.
FEBS letters 2012;586(11):1612-6.
2011: Toshiaki Hashimoto; Ushio Kikkawa; Shinji Kamada
Contribution of caspase(s) to the cell cycle regulation at mitotic phase.
PloS one 2011;6(3):e18449.
2010: Masahiro Oka; Masanobu Sakaguchi; Taro Okada; Hiroshi Nagai; Michitaka Ozaki; Toyo Yoshioka; Hiroshi Inoue; Naofumi Mukaida; Ushio Kikkawa; Chikako Nishigori
Signal transducer and activator of transcription 3 upregulates interleukin-8 expression at the level of transcription in human melanoma cells.
Experimental dermatology 2010;19(8):e50-5.
2009: Satoshi Eguchi; Noriko Oshiro; Takafumi Miyamoto; Ken-Ichi Yoshino; Sumiko Okamoto; Takamasa Ono; Ushio Kikkawa; Kazuyoshi Yonezawa
AMP-activated protein kinase phosphorylates glutamine : fructose-6-phosphate amidotransferase 1 at Ser243 to modulate its enzymatic activity.
Genes to cells : devoted to molecular & cellular mechanisms 2009;14(2):179-89.
2008: Toshiaki Hashimoto; Lisa Yamauchi; Tony Hunter; Ushio Kikkawa; Shinji Kamada
Possible involvement of caspase-7 in cell cycle progression at mitosis.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(6):609-21.
2008: Takafumi Miyamoto; Noriko Oshiro; Ken-Ichi Yoshino; Akio Nakashima; Satoshi Eguchi; Mikiko Takahashi; Yoshitaka Ono; Ushio Kikkawa; Kazuyoshi Yonezawa
AMP-activated protein kinase phosphorylates Golgi-specific brefeldin A resistance factor 1 at Thr1337 to induce disassembly of Golgi apparatus.
The Journal of biological chemistry 2008;283(7):4430-8.
2008: Akio Nakashima; Yoshiko Maruki; Yuko Imamura; Chika Kondo; Tomoko Kawamata; Ippei Kawanishi; Hideki Takata; Akira Matsuura; Kyung S Lee; Ushio Kikkawa; Yoshinori Ohsumi; Kazuyoshi Yonezawa; Yoshiaki Kamada
The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase.
PloS one 2008;3(5):e2223.
2008: Masakatsu Morita; Hidenori Matsuzaki; Toshiyoshi Yamamoto; Yasuo Fukami; Ushio Kikkawa
Epidermal growth factor receptor phosphorylates protein kinase C {delta} at Tyr332 to form a trimeric complex with p66Shc in the H2O2-stimulated cells.
Journal of biochemistry 2008;143(1):31-8.
2008: Masahiro Oka; Ushio Kikkawa; Chikako Nishigori
Protein kinase C-betaII represses hepatocyte growth factor-induced invasion by preventing the association of adapter protein Gab1 and phosphatidylinositol 3-kinase in melanoma cells.
The Journal of investigative dermatology 2008;128(1):188-95.
2007: Akio Nakashima; Ken-ichi Yoshino; Takafumi Miyamoto; Satoshi Eguchi; Noriko Oshiro; Ushio Kikkawa; Kazuyoshi Yonezawa
Identification of TBC7 having TBC domain as a novel binding protein to TSC1-TSC2 complex.
Biochemical and biophysical research communications 2007;361(1):218-23.
2007: Noriko Oshiro; Rinako Takahashi; Ken-ichi Yoshino; Keiko Tanimura; Akio Nakashima; Satoshi Eguchi; Takafumi Miyamoto; Kenta Hara; Kenji Takehana; Joseph Avruch; Ushio Kikkawa; Kazuyoshi Yonezawa
The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1.
The Journal of biological chemistry 2007;282(28):20329-39.
2006: Satoshi Eguchi; Chiharu Tokunaga; Sujuti Hidayat; Noriko Oshiro; Ken-ichi Yoshino; Ushio Kikkawa; Kazuyoshi Yonezawa
Different roles for the TOS and RAIP motifs of the translational regulator protein 4E-BP1 in the association with raptor and phosphorylation by mTOR in the regulation of cell size.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(7):757-66.
2006: Takehiro Matsubara; Yasuhito Shirai; Kei Miyasaka; Takuya Murakami; Yasuto Yamaguchi; Takehiko Ueyama; Masahiro Kai; Fumio Sakane; Hideo Kanoh; Toshiaki Hashimoto; Shinji Kamada; Ushio Kikkawa; Naoaki Saito
Nuclear transportation of diacylglycerol kinase gamma and its possible function in the nucleus.
The Journal of biological chemistry 2006;281(10):6152-64.
2006: Sayaka Umada-Kajimoto; Toshiyoshi Yamamoto; Hidenori Matsuzaki; Ushio Kikkawa
The complex formation of PKCdelta through its C1- and C2-like regions in H2O2-stimulated cells.
Biochemical and biophysical research communications 2006;341(1):101-7.
2006: Toshiyoshi Yamamoto; Hidenori Matsuzaki; Shinji Kamada; Yoshitaka Ono; Ushio Kikkawa
Biochemical assays for multiple activation states of protein kinase C.
Nature protocols 2006;1(6):2791-5.
2006: Goh Ohji; Sujuti Hidayat; Akio Nakashima; Chiharu Tokunaga; Noriko Oshiro; Ken-Ichi Yoshino; Koichi Yokono; Ushio Kikkawa; Kazuyoshi Yonezawa
Suppression of the mTOR-raptor signaling pathway by the inhibitor of heat shock protein 90 geldanamycin.
Journal of biochemistry 2006;139(1):129-35.
2005: Shinji Kamada; Ushio Kikkawa; Yoshihide Tsujimoto; Tony Hunter
A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association.
Molecular and cellular biology 2005;25(21):9469-77.
2005: Hidenori Matsuzaki; Akira Ichino; Tadahiro Hayashi; Toshiyoshi Yamamoto; Ushio Kikkawa
Regulation of intracellular localization and transcriptional activity of FOXO4 by protein kinase B through phosphorylation at the motif sites conserved among the FOXO family.
Journal of biochemistry 2005;138(4):485-91.
2005: Masahiro Oka; Ushio Kikkawa
Protein kinase C in melanoma.
Cancer metastasis reviews 2005;24(2):287-300.
2005: Shinji Kamada; Ushio Kikkawa; Yoshihide Tsujimoto; Tony Hunter
Nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s).
The Journal of biological chemistry 2005;280(2):857-60.
2004: Hidenori Matsuzaki; Toshiyoshi Yamamoto; Ushio Kikkawa
Distinct activation mechanisms of protein kinase B by growth-factor stimulation and heat-shock treatment.
Biochemistry 2004;43(14):4284-93.
2004: Taketoshi Kajimoto; Yasuhito Shirai; Norio Sakai; Toshiyoshi Yamamoto; Hidenori Matsuzaki; Ushio Kikkawa; Naoaki Saito
Ceramide-induced apoptosis by translocation, phosphorylation, and activation of protein kinase Cdelta in the Golgi complex.
The Journal of biological chemistry 2004;279(13):12668-76.
2003: Masahiro Oka; Taro Okada; Shun-ichi Nakamura; Motoi Ohba; Toshio Kuroki; Ushio Kikkawa; Hiroshi Nagai; Masamitsu Ichihashi; Chikako Nishigori
PKCdelta inhibits PKCalpha-mediated activation of phospholipase D1 in a manner independent of its protein kinase activity.
FEBS letters 2003;554(1-2):179-83.
2003: Toshiyoshi Yamamoto; Emiko Yamauchi; Hisaaki Taniguchi; Hidenori Matsuzaki; Ushio Kikkawa
Tyrosine phosphorylation of protein kinase C.
Methods in molecular biology (Clifton, N.J.) 2003;233():207-16.
2003: Yasutomi Nishizuka; Ushio Kikkawa
Early studies of protein kinase C: a historical perspective.
Methods in molecular biology (Clifton, N.J.) 2003;233():9-18.
2002: Ushio Kikkawa; Hidenori Matsuzaki; Toshiyoshi Yamamoto
Protein kinase C delta (PKC delta): activation mechanisms and functions.
Journal of biochemistry 2002;132(6):831-9.
2002: Masahiro Oka; Tomohiro Hitomi; Taro Okada; Shun-ichi Nakamura Si; Hiroshi Nagai; Motoi Ohba; Toshio Kuroki; Ushio Kikkawa; Masamitsu Ichihashi
Dual regulation of phospholipase D1 by protein kinase C alpha in vivo.
Biochemical and biophysical research communications 2002;294(5):1109-13.
2002: Daisuke Matsuoka; Takashi Nanmori; Ken-ichi Sato; Yasuo Fukami; Ushio Kikkawa; Takeshi Yasuda
Activation of AtMEK1, an Arabidopsis mitogen-activated protein kinase kinase, in vitro and in vivo: analysis of active mutants expressed in E. coli and generation of the active form in stress response in seedlings.
The Plant journal : for cell and molecular biology 2002;29(5):637-47.
2002: Naoaki Saito; Ushio Kikkawa; Yasutomi Nishizuka
The family of protein kinase C and membrane lipid mediators.
Journal of diabetes and its complications 2002;16(1):4-8.
2001: Michiru Fukunaga; Masahiro Oka; Masamitsu Ichihashi; Toshiyoshi Yamamoto; Hidenori Matsuzaki; Ushio Kikkawa
UV-induced tyrosine phosphorylation of PKC delta and promotion of apoptosis in the HaCaT cell line.
Biochemical and biophysical research communications 2001;289(2):573-9.
2001: H Konishi; E Yamauchi; H Taniguchi; Toshiyoshi Yamamoto; Hidenori Matsuzaki; Y Takemura; K Ohmae; Ushio Kikkawa; Yasutomi Nishizuka
Phosphorylation sites of protein kinase C delta in H2O2-treated cells and its activation by tyrosine kinase in vitro.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(12):6587-92.
2000: Masahiro Oka; Hiroshi Nagai; H Ando; M Fukunaga; M Matsumura; K Araki; W Ogawa; T Miki; M Sakaue; K Tsukamoto; H Konishi; Ushio Kikkawa; Masamitsu Ichihashi
Regulation of melanogenesis through phosphatidylinositol 3-kinase-Akt pathway in human G361 melanoma cells.
The Journal of investigative dermatology 2000;115(4):699-703.
2000: Toshiyoshi Yamamoto; Hidenori Matsuzaki; H Konishi; Yoshitaka Ono; Ushio Kikkawa
H(2)O(2)-induced tyrosine phosphorylation of protein kinase cdelta by a mechanism independent of inhibition of protein-tyrosine phosphatase in CHO and COS-7 cells.
Biochemical and biophysical research communications 2000;273(3):960-6.
1999: H Konishi; T Fujiyoshi; Y Fukui; Hidenori Matsuzaki; Toshiyoshi Yamamoto; Yoshitaka Ono; M Andjelkovic; B A Hemmings; Ushio Kikkawa
Activation of protein kinase B induced by H(2)O(2) and heat shock through distinct mechanisms dependent and independent of phosphatidylinositol 3-kinase.
Journal of biochemistry 1999;126(6):1136-43.
1999: H Konishi; Hidenori Matsuzaki; Hiroshi Takaishi; Toshiyoshi Yamamoto; Michiru Fukunaga; Yoshitaka Ono; Ushio Kikkawa
Opposing effects of protein kinase C delta and protein kinase B alpha on H(2)O(2)-induced apoptosis in CHO cells.
Biochemical and biophysical research communications 1999;264(3):840-6.
1999: Hiroshi Takaishi; H Konishi; Hidenori Matsuzaki; Yoshitaka Ono; Y Shirai; Naoaki Saito; T Kitamura; W Ogawa; M Kasuga; Ushio Kikkawa; Yasutomi Nishizuka
Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(21):11836-41.
1999: Tetsuya Yamamoto; Hiroshi Takeuchi; Takashi Kanematsu; V Allen; Hitoshi Yagisawa; Ushio Kikkawa; Y Watanabe; Akihiko Nakasima; M Katan; Masato Hirata
Involvement of EF hand motifs in the Ca(2+)-dependent binding of the pleckstrin homology domain to phosphoinositides.
European journal of biochemistry / FEBS 1999;265(1):481-90.
1999: T Kitamura; Y Kitamura; Shun'ichi Kuroda; Y Hino; M Ando; Ko Kotani; H Konishi; H Matsuzaki; Ushio Kikkawa; Wataru Ogawa; Masato Kasuga
Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt.
Molecular and cellular biology 1999;19(9):6286-96.
1999: H Kiriyama; Takashi Nanmori; K Hari; Daisuke Matsuoka; Yasuo Fukami; Ushio Kikkawa; Takeshi Yasuda
Identification of the catalytic subunit of cAMP-dependent protein kinase from the photosynthetic flagellate, Euglena gracilis Z.
FEBS letters 1999;450(1-2):95-100.
1999: Motofumi Tanaka; H Konishi; K Touhara; Fumio Sakane; Masato Hirata; Yoshitaka Ono; Ushio Kikkawa
Identification of myosin II as a binding protein to the PH domain of protein kinase B.
Biochemical and biophysical research communications 1999;255(1):169-74.
1998: Shun-Ichi Nakamura; T Akisue; H Jinnai; Tomohiro Hitomi; S Sarkar; Noriko Miwa; Taro Okada; K Yoshida; Shun'ichi Kuroda; Ushio Kikkawa; Yasutomi Nishizuka
Requirement of GM2 ganglioside activator for phospholipase D activation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12249-53.
1998: Chiharu Tokunaga; Kenji Tatematsu; Shun'ichi Kuroda; N Nakagawa; Ushio Kikkawa
Molecular cloning and characterization of RBCK2, a splicing variant of a RBCC family protein, RBCK1.
FEBS letters 1998;435(1):11-5.
1998: S Ohmori; Yasuhito Shirai; Norio Sakai; M Fujii; H Konishi; Ushio Kikkawa; Naoaki Saito
Three distinct mechanisms for translocation and activation of the delta subspecies of protein kinase C.
Molecular and cellular biology 1998;18(9):5263-71.
1998: Shun'ichi Kuroda; Wataru Ogawa; T Kitamura; H Konishi; Ushio Kikkawa; Masato Kasuga
Requirement of the serine-threonine kinase Akt for heat treatment-induced activation of p70 S6 kinase.
Biochemical and biophysical research communications 1998;249(3):781-5.
1998: Hiroshi Takeuchi; M Matsuda; Tetsuya Yamamoto; Takashi Kanematsu; Ushio Kikkawa; Hitoshi Yagisawa; Y Watanabe; Masato Hirata
PTB domain of insulin receptor substrate-1 binds inositol compounds.
The Biochemical journal 1998;334 ( Pt 1)():211-8.
1998: T Kitamura; Wataru Ogawa; Hiroshi Sakaue; Y Hino; Shun'ichi Kuroda; M Takata; M Matsumoto; T Maeda; H Konishi; Ushio Kikkawa; Masato Kasuga
Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport.
Molecular and cellular biology 1998;18(7):3708-17.
1998: Kenji Tatematsu; Chiharu Tokunaga; N Nakagawa; Katsuyuki Tanizawa; Shun'ichi Kuroda; Ushio Kikkawa
Transcriptional activity of RBCK1 protein (RBCC protein interacting with PKC 1): requirement of RING-finger and B-Box motifs and regulation by protein kinases.
Biochemical and biophysical research communications 1998;247(2):392-6.
1998: Chiharu Tokunaga; Shun'ichi Kuroda; Kenji Tatematsu; N Nakagawa; Yoshitaka Ono; Ushio Kikkawa
Molecular cloning and characterization of a novel protein kinase C-interacting protein with structural motifs related to RBCC family proteins.
Biochemical and biophysical research communications 1998;244(2):353-9.
1998: H Yoshida; Y Tsujishita; F Hullin; K Yoshida; Sachiko Nakamura; Ushio Kikkawa; Y Asaoka
Isolation and properties of a novel phospholipase A from rat brain that hydrolyses fatty acids at sn-1 and sn-2 positions.
Annals of clinical biochemistry 1998;35 ( Pt 2)():295-301.
1997: Hiroshi Takeuchi; Takashi Kanematsu; Yoshio Misumi; Fumio Sakane; H Konishi; Ushio Kikkawa; Y Watanabe; M Katan; Masato Hirata
Distinct specificity in the binding of inositol phosphates by pleckstrin homology domains of pleckstrin, RAC-protein kinase, diacylglycerol kinase and a new 130 kDa protein.
Biochimica et biophysica acta 1997;1359(3):275-85.
1997: H Konishi; M Tanaka; Y Takemura; Hidenori Matsuzaki; Yoshitaka Ono; Ushio Kikkawa; Yasutomi Nishizuka
Activation of protein kinase C by tyrosine phosphorylation in response to H2O2.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11233-7.
1997: H Konishi; H Matsuzaki; M Tanaka; Y Takemura; Shun'ichi Kuroda; Y Ono; Ushio Kikkawa
Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp27.
FEBS letters 1997;410(2-3):493-8.
1997: M Kadotani; Teruaki Nishiuma; M Nanahoshi; Y Tsujishita; K Ogita; Sachiko Nakamura; Ushio Kikkawa; Y Asaoka
Characterization of tyrosine-phosphorylated delta isoform of protein kinase C isolated from Chinese hamster ovary cells.
Journal of biochemistry 1997;121(6):1047-53.
1996: Shun'ichi Kuroda; Chiharu Tokunaga; Y Kiyohara; O Higuchi; H Konishi; K Mizuno; G N Gill; Ushio Kikkawa
Protein-protein interaction of zinc finger LIM domains with protein kinase C.
The Journal of biological chemistry 1996;271(49):31029-32.
1996: H Matsuzaki; H Konishi; M Tanaka; Yoshitaka Ono; T Takenawa; Y Watanabe; S Ozaki; Shun'ichi Kuroda; Ushio Kikkawa
Isolation of the active form of RAC-protein kinase (PKB/Akt) from transfected COS-7 cells treated with heat shock stress and effects of phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 4,5-bisphosphate on its enzyme activity.
FEBS letters 1996;396(2-3):305-8.
1996: H Konishi; Hidenori Matsuzaki; M Tanaka; Yoshitaka Ono; Chiharu Tokunaga; Shun'ichi Kuroda; Ushio Kikkawa
Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7639-43.
1995: H Konishi; Shun'ichi Kuroda; M Tanaka; Hidenori Matsuzaki; Yoshitaka Ono; K Kameyama; T Haga; Ushio Kikkawa
Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins.
Biochemical and biophysical research communications 1995;216(2):526-34.
1995: H Takanaga; Hideyuki Mukai; M Shimakawa; H Konishi; Ushio Kikkawa; T Koizumi; Yoshitaka Ono
Functional characterization of the promoter region of the mouse protein kinase C gamma gene.
FEBS letters 1995;368(2):276-8.
1995: K Kasahara; Ushio Kikkawa
Distinct effects of saturated fatty acids on protein kinase C subspecies.
Journal of biochemistry 1995;117(3):648-53.
1994: H Konishi; Shun'ichi Kuroda; Ushio Kikkawa
The pleckstrin homology domain of RAC protein kinase associates with the regulatory domain of protein kinase C zeta.
Biochemical and biophysical research communications 1994;205(3):1770-5.
1994: H Konishi; T Shinomura; Shun'ichi Kuroda; Yoshitaka Ono; Ushio Kikkawa
Molecular cloning of rat RAC protein kinase alpha and beta and their association with protein kinase C zeta.
Biochemical and biophysical research communications 1994;205(1):817-25.
1994: T Nanmori; W Taguchi; M Kinugasa; Y Oji; S Sahara; Yasuo Fukami; Ushio Kikkawa
Purification and characterization of protein kinase C from a higher plant, Brassica campestris L.
Biochemical and biophysical research communications 1994;203(1):311-8.
1992: T Iwai; N Fujisawa; K Ogita; Ushio Kikkawa
Catalytic properties of yeast protein kinase C: difference between the yeast and mammalian enzymes.
Journal of biochemistry 1992;112(1):7-10.
1992: K Ogita; S Miyamoto; K Yamaguchi; H Koide; N Fujisawa; Ushio Kikkawa; S Sahara; Yasuo Fukami; Yasutomi Nishizuka
Isolation and characterization of delta-subspecies of protein kinase C from rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(5):1592-6.
1992: H Koide; K Ogita; Ushio Kikkawa; Yasutomi Nishizuka
Isolation and characterization of the epsilon subspecies of protein kinase C from rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1149-53.
1992: Y Asaoka; K Yoshida; Masahiro Oka; T Shinomura; H Koide; K Ogita; Ushio Kikkawa; Yasutomi Nishizuka
The family of protein kinase C in transmembrane signalling for cellular regulation.
Journal of nutritional science and vitaminology 1992;Spec No():7-12.
1991: Yasutomi Nishizuka; M S Shearman; T Oda; N Berry; T Shinomura; Y Asaoka; K Ogita; H Koide; Ushio Kikkawa; A Kishimoto
Protein kinase C family and nervous function.
Progress in brain research 1991;89():125-41.
1990: K Ogita; H Koide; Ushio Kikkawa; A Kishimoto; Yasutomi Nishizuka
The heterogeneity of protein kinase C in signal transduction cascade.
Advances in second messenger and phosphoprotein research 1990;24():218-23.
1989: N Berry; K Ase; Ushio Kikkawa; A Kishimoto; Yasutomi Nishizuka
Human T cell activation by phorbol esters and diacylglycerol analogues.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(5):1407-13.
1989: Naoaki Saito; A Kose; A Ito; Kohkichi Hosoda; M Mori; M Hirata; K Ogita; Ushio Kikkawa; Yoshitaka Ono; K Igarashi
Immunocytochemical localization of beta II subspecies of protein kinase C in rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3409-13.
1989: S Sawamura; K Ase; N Berry; Ushio Kikkawa; P G McCaffrey; J Minowada; Yasutomi Nishizuka
Expression of protein kinase C subspecies in human leukemia-lymphoma cell lines.
FEBS letters 1989;247(2):353-7.
1989: Kohkichi Hosoda; Naoaki Saito; A Kose; A Ito; T Tsujino; K Ogita; Ushio Kikkawa; Yoshitaka Ono; K Igarashi; Yasutomi Nishizuka
Immunocytochemical localization of the beta I subspecies of protein kinase C in rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(4):1393-7.
1989: A Kishimoto; Ushio Kikkawa; K Ogita; M S Shearman; Yasutomi Nishizuka
The protein kinase C family in the brain: heterogeneity and its implications.
Annals of the New York Academy of Sciences 1989;568():181-6.
1989: Ushio Kikkawa; A Kishimoto; Yasutomi Nishizuka
The protein kinase C family: heterogeneity and its implications.
Annual review of biochemistry 1989;58():31-44.
1989: K Ogita; Ushio Kikkawa; M S Shearman; K Ase; N Berry; A Kishimoto; Yasutomi Nishizuka
The structure and function of multispecies of protein kinase C.
Advances in prostaglandin, thromboxane, and leukotriene research 1989;19():49-56.
1988: A Kose; Naoaki Saito; H Ito; Ushio Kikkawa; Yasutomi Nishizuka; C Tanaka
Electron microscopic localization of type I protein kinase C in rat Purkinje cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(11):4262-8.
1988: K Ase; Naoaki Saito; M S Shearman; Ushio Kikkawa; Y Ono; K Igarashi; C Tanaka; Yasutomi Nishizuka
Distinct cellular expression of beta I- and beta II-subspecies of protein kinase C in rat cerebellum.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(10):3850-6.
1988: M Tsukuda; Y Asaoka; K Sekiguchi; Ushio Kikkawa; Yasutomi Nishizuka
Properties of protein kinase C subspecies in human platelets.
Biochemical and biophysical research communications 1988;155(3):1387-95.
1988: K Ase; N Berry; Ushio Kikkawa; A Kishimoto; Yasutomi Nishizuka
Differential down-regulation of protein kinase C subspecies in KM3 cells.
FEBS letters 1988;236(2):396-400.
1988: M S Shearman; K Ase; N Saito; K Sekiguchi; K Ogita; Ushio Kikkawa; C Tanaka; Yasutomi Nishizuka
Molecular heterogeneity and differential expression of multiple protein kinase C subspecies in central nervous tissue.
Biochemical Society transactions 1988;16(4):460-3.
1988: Ushio Kikkawa; K Ogita; M S Shearman; K Ase; K Sekiguchi; Z Naor; M Ido; Yasutomi Nishizuka; N Saito; C Tanaka
The heterogeneity and differential expression of protein kinase C in nervous tissues.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1988;320(1199):313-24.
1988: M S Shearman; N Berry; T Oda; K Ase; Ushio Kikkawa; Yasutomi Nishizuka
Isolation of protein kinase C subspecies from a preparation of human T lymphocytes.
FEBS letters 1988;234(2):387-91.
1988: T Hashimoto; K Ase; S Sawamura; Ushio Kikkawa; Naoaki Saito; C Tanaka; Yasutomi Nishizuka
Postnatal development of a brain-specific subspecies of protein kinase C in rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(5):1678-83.
1988: K Sekiguchi; M Tsukuda; K Ase; Ushio Kikkawa; Yasutomi Nishizuka
Mode of activation and kinetic properties of three distinct forms of protein kinase C from rat brain.
Journal of biochemistry 1988;103(5):759-65.
1988: Y Asaoka; Ushio Kikkawa; K Sekiguchi; M S Shearman; Y Kosaka; Y Nakano; T Satoh; Yasutomi Nishizuka
Activation of a brain-specific protein kinase C subspecies in the presence of phosphatidylethanol.
FEBS letters 1988;231(1):221-4.
1988: Y Kosaka; K Ogita; K Ase; H Nomura; Ushio Kikkawa; Yasutomi Nishizuka
The heterogeneity of protein kinase C in various rat tissues.
Biochemical and biophysical research communications 1988;151(3):973-81.
1988: Naoaki Saito; Ushio Kikkawa; Yasutomi Nishizuka; C Tanaka
Distribution of protein kinase C-like immunoreactive neurons in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(2):369-82.
1988: Ushio Kikkawa; K Ogita; M S Shearman; K Ase; K Sekiguchi; Z Naor; A Kishimoto; Yasutomi Nishizuka; N Saito; C Tanaka
The family of protein kinase C: its molecular heterogeneity and differential expression.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 1():97-102.
1988: Ushio Kikkawa; K Ogita; M Go; H Nomura; T Kitano; T Hashimoto; K Ase; K Sekiguchi; J Koumoto; Yasutomi Nishizuka
Protein kinase C in transmembrane signaling.
Advances in second messenger and phosphoprotein research 1988;21():67-74.
1987: Ushio Kikkawa; K Ogita; Yoshitaka Ono; Y Asaoka; M S Shearman; T Fujii; K Ase; K Sekiguchi; K Igarashi; Yasutomi Nishizuka
The common structure and activities of four subspecies of rat brain protein kinase C family.
FEBS letters 1987;223(2):212-6.
1987: M S Shearman; Z Naor; Ushio Kikkawa; Yasutomi Nishizuka
Differential expression of multiple protein kinase C subspecies in rat central nervous tissue.
Biochemical and biophysical research communications 1987;147(3):911-9.
1987: P G McCaffrey; M R Rosner; Ushio Kikkawa; K Sekiguchi; K Ogita; K Ase; Yasutomi Nishizuka
Characterization of protein kinase C from normal and transformed cultured murine fibroblasts.
Biochemical and biophysical research communications 1987;146(1):140-6.
1987: M Go; H Nomura; T Kitano; J Koumoto; Ushio Kikkawa; N Saito; C Tanaka; Yasutomi Nishizuka
Inositol phospholipid turnover and protein phosphorylation in secretory responses.
Annals of the New York Academy of Sciences 1987;493():552-62.
1986: Ushio Kikkawa; M Go; J Koumoto; Yasutomi Nishizuka
Rapid purification of protein kinase C by high performance liquid chromatography.
Biochemical and biophysical research communications 1986;135(2):636-43.