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Michael Kilberg

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Jaeseok Han; Maria Hatzoglou; Junguk Hur; Michael S Kilberg; Dawid Krokowski; Yu-Hsuan Lin; Maureen A Sartor; Jixiu Shan; Shiyu Wang; Celvie L Yuan; Sung Hoon Back; Robert Gildersleeve; Randal J Kaufman
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.
Mukundh N Balasubramanian; Elizabeth A Butterworth; Michael S Kilberg
Asparagine synthetase: regulation by cell stress and involvement in tumor biology.
Lingchen Fu; Michael S Kilberg
Elevated cJUN expression and an ATF/CRE site within the ATF3 promoter contribute to activation of ATF3 transcription by the amino acid response.

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2013: Jaeseok Han; Maria Hatzoglou; Junguk Hur; Michael S Kilberg; Dawid Krokowski; Yu-Hsuan Lin; Maureen A Sartor; Jixiu Shan; Shiyu Wang; Celvie L Yuan; Sung Hoon Back; Robert Gildersleeve; Randal J Kaufman
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.
Nature cell biology 2013;15(5):481-90.
2013: Mukundh N Balasubramanian; Elizabeth A Butterworth; Michael S Kilberg
Asparagine synthetase: regulation by cell stress and involvement in tumor biology.
American journal of physiology. Endocrinology and metabolism 2013;304(8):E789-99.
2013: Lingchen Fu; Michael S Kilberg
Elevated cJUN expression and an ATF/CRE site within the ATF3 promoter contribute to activation of ATF3 transcription by the amino acid response.
Physiological genomics 2013;45(4):127-37.
2013: Mukundh N Balasubramanian; Jixiu Shan; Michael S Kilberg
Dynamic changes in genomic histone association and modification during activation of the ASNS and ATF3 genes by amino acid limitation.
The Biochemical journal 2013;449(1):219-29.
2012: Jixiu Shan; Tracy Anthony; Mukundh N Balasubramanian; Lingchen Fu; Michael S Kilberg
ATF4-dependent regulation of the JMJD3 gene during amino acid deprivation can be rescued in Atf4-deficient cells by inhibition of deacetylation.
The Journal of biological chemistry 2012;287(43):36393-403.
2012: Michael S Kilberg; Mukundh Balasubramanian; Lingchen Fu; Jixiu Shan
The transcription factor network associated with the amino acid response in mammalian cells.
Advances in nutrition (Bethesda, Md.) 2012;3(3):295-306.
2011: Lingchen Fu; Mukundh Balasubramanian; Elizabeth E Dudenhausen; Jixiu Shan; Michael S Kilberg
Auto-activation of c-JUN gene by amino acid deprivation of hepatocellular carcinoma cells reveals a novel c-JUN-mediated signaling pathway.
The Journal of biological chemistry 2011;286(42):36724-38.
2009: Michael S Kilberg; Jixiu Shan; Nan Su
ATF4-dependent transcription mediates signaling of amino acid limitation.
Trends in endocrinology and metabolism: TEM 2009;20(9):436-43.
2009: Jixiu Shan; Daima Ord; Tõnis Ord; Michael S Kilberg
Elevated ATF4 expression, in the absence of other signals, is sufficient for transcriptional induction via CCAAT enhancer-binding protein-activating transcription factor response elements.
The Journal of biological chemistry 2009;284(32):21241-8.
2009: Nan Su; Michelle M Thiaville; Keytam Awad; Altin Gjymishka; Jason O Brant; Thomas P Yang; Michael S Kilberg
Protein or amino acid deprivation differentially regulates the hepatic forkhead box protein A (FOXA) genes through an activating transcription factor-4-independent pathway.
Hepatology (Baltimore, Md.) 2009;50(1):282-90.
2009: Stela S Palii; C E Kays; C Deval; A Bruhat; P Fafournoux; Michael S Kilberg
Specificity of amino acid regulated gene expression: analysis of genes subjected to either complete or single amino acid deprivation.
Amino acids 2009;37(1):79-88.
2009: Altin Gjymishka; Nan Su; Michael S Kilberg
Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway.
The Biochemical journal 2009;417(3):695-703.
2008: Nan Su; Michael S Kilberg
C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene.
The Journal of biological chemistry 2008;283(50):35106-17.
2008: Altin Gjymishka; Stela S Palii; Jixiu Shan; Michael S Kilberg
Despite increased ATF4 binding at the C/EBP-ATF composite site following activation of the unfolded protein response, system A transporter 2 (SNAT2) transcription activity is repressed in HepG2 cells.
The Journal of biological chemistry 2008;283(41):27736-47.
2008: Michelle M Thiaville; Elizabeth E Dudenhausen; Keytam S Awad; Altin Gjymishka; Can Zhong; Michael S Kilberg
Activated transcription via mammalian amino acid response elements does not require enhanced recruitment of the Mediator complex.
Nucleic acids research 2008;36(17):5571-80.
2008: Susan E Abbatiello; Yuan-Xiang Pan; Mi Zhou; ALAN WAYNE; Timothy D Veenstra; Stephen P Hunger; Michael S Kilberg; John R Eyler; Nigel G J Richards; Thomas P Conrads
Mass spectrometric quantification of asparagine synthetase in circulating leukemia cells from acute lymphoblastic leukemia patients.
Journal of proteomics 2008;71(1):61-70.
2008: Michelle M Thiaville; Yuan-Xiang Pan; Altin Gjymishka; Can Zhong; Randal J Kaufman; Michael S Kilberg
MEK signaling is required for phosphorylation of eIF2alpha following amino acid limitation of HepG2 human hepatoma cells.
The Journal of biological chemistry 2008;283(16):10848-57.
2008: Kimberly J Aiken; Justin S Bickford; Michael S Kilberg; Harry S Nick
Metabolic regulation of manganese superoxide dismutase expression via essential amino acid deprivation.
The Journal of biological chemistry 2008;283(16):10252-63.
2008: Michelle M Thiaville; Elizabeth E Dudenhausen; Can Zhong; Yuan-Xiang Pan; Michael S Kilberg
Deprivation of protein or amino acid induces C/EBPbeta synthesis and binding to amino acid response elements, but its action is not an absolute requirement for enhanced transcription.
The Biochemical journal 2008;410(3):473-84.
2008: Nan Su; Yuan-Xiang Pan; Mi Zhou; Richard C Harvey; Stephen P Hunger; Michael S Kilberg
Correlation between asparaginase sensitivity and asparagine synthetase protein content, but not mRNA, in acute lymphoblastic leukemia cell lines.
Pediatric blood & cancer 2008;50(2):274-9.
2007: Yuan-Xiang Pan; Hong Chen; Michelle M Thiaville; Michael S Kilberg
Activation of the ATF3 gene through a co-ordinated amino acid-sensing response programme that controls transcriptional regulation of responsive genes following amino acid limitation.
The Biochemical journal 2007;401(1):299-307.
2006: Jemy A Gutierrez; Yuan-Xiang Pan; Lukasz Koroniak; Jun Hiratake; Michael S Kilberg; Nigel G J Richards
An inhibitor of human asparagine synthetase suppresses proliferation of an L-asparaginase-resistant leukemia cell line.
Chemistry & biology 2006;13(12):1339-47.
2006: Hong Chen; Michael S Kilberg
Alignment of the transcription start site coincides with increased transcriptional activity from the human asparagine synthetase gene following amino acid deprivation of HepG2 cells.
The Journal of nutrition 2006;136(10):2463-7.
2006: Stela S Palii; Michelle M Thiaville; Yuan-Xiang Pan; Can Zhong; Michael S Kilberg
Characterization of the amino acid response element within the human sodium-coupled neutral amino acid transporter 2 (SNAT2) System A transporter gene.
The Biochemical journal 2006;395(3):517-27.
2006: Nigel G J Richards; Michael S Kilberg
Asparagine synthetase chemotherapy.
Annual review of biochemistry 2006;75():629-54.
2005: Chin Chen; Elizabeth E Dudenhausen; Hong Chen; Yuan-Xiang Pan; Altin Gjymishka; Michael S Kilberg
Amino-acid limitation induces transcription from the human C/EBPbeta gene via an enhancer activity located downstream of the protein coding sequence.
The Biochemical journal 2005;391(Pt 3):649-58.
2005: Yuan-Xiang Pan; Hong Chen; Michael S Kilberg
Interaction of RNA-binding proteins HuR and AUF1 with the human ATF3 mRNA 3'-untranslated region regulates its amino acid limitation-induced stabilization.
The Journal of biological chemistry 2005;280(41):34609-16.
2005: Michael S Kilberg; Y-X Pan; Hong Chen; Van Leung-Pineda
Nutritional control of gene expression: how mammalian cells respond to amino acid limitation.
Annual review of nutrition 2005;25():59-85.
2004: Hong Chen; Yuan-Xiang Pan; Elizabeth E Dudenhausen; Michael S Kilberg
Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive basic region/leucine zipper transcription factors as well as localized histone acetylation.
The Journal of biological chemistry 2004;279(49):50829-39.
2004: Chin Chen; Elizabeth E Dudenhausen; Yuan-Xiang Pan; Can Zhong; Michael S Kilberg
Human CCAAT/enhancer-binding protein beta gene expression is activated by endoplasmic reticulum stress through an unfolded protein response element downstream of the protein coding sequence.
The Journal of biological chemistry 2004;279(27):27948-56.
2004: Van Leung-Pineda; YuanXiang Pan; Hong Chen; Michael S Kilberg
Induction of p21 and p27 expression by amino acid deprivation of HepG2 human hepatoma cells involves mRNA stabilization.
The Biochemical journal 2004;379(Pt 1):79-88.
2004: Stela S Palii; Hong Chen; Michael S Kilberg
Transcriptional control of the human sodium-coupled neutral amino acid transporter system A gene by amino acid availability is mediated by an intronic element.
The Journal of biological chemistry 2004;279(5):3463-71.
2003: Brant R Burkhardt; Scott A Loiler; Jo Anne Anderson; Michael S Kilberg; James M Crawford; Terence R Flotte; Kevin S Goudy; Tamir M Ellis; Mark Atkinson
Glucose-responsive expression of the human insulin promoter in HepG2 human hepatoma cells.
Annals of the New York Academy of Sciences 2003;1005():237-41.
2003: YuanXiang Pan; Hong Chen; Fai Siu; Michael S Kilberg
Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple activating transcription factor-3 mRNA species that, when overexpressed in HepG2 cells, modulate transcription by the human asparagine synthetase promoter.
The Journal of biological chemistry 2003;278(40):38402-12.
2003: Michael D Weiss; Shag Derazi; Candace Rossignol; Hélène Varoqui; Jeffrey D Erickson; Michael S Kilberg; Kevin J Anderson
Ontogeny of the neutral amino acid transporter SAT1/ATA1 in rat brain.
Brain research. Developmental brain research 2003;143(2):151-9.
2003: Can Zhong; Chin Chen; Michael S Kilberg
Characterization of the nutrient-sensing response unit in the human asparagine synthetase promoter.
The Biochemical journal 2003;372(Pt 2):603-9.
2003: Se-Ho Chang; Jairo Garcia; J Andres Melendez; Michael S Kilberg; Anupam Agarwal
Haem oxygenase 1 gene induction by glucose deprivation is mediated by reactive oxygen species via the mitochondrial electron-transport chain.
The Biochemical journal 2003;371(Pt 3):877-85.
2002: Alain Bruhat; Julien Averous; Valérie Carraro; Can Zhong; Andreas M Reimold; Michael S Kilberg; Pierre Fafournoux
Differences in the molecular mechanisms involved in the transcriptional activation of the CHOP and asparagine synthetase genes in response to amino acid deprivation or activation of the unfolded protein response.
The Journal of biological chemistry 2002;277(50):48107-14.
2002: Wenbo Yang; Michael S Kilberg
Biosynthesis, intracellular targeting, and degradation of the EAAC1 glutamate/aspartate transporter in C6 glioma cells.
The Journal of biological chemistry 2002;277(41):38350-7.
2002: Perry J Bain; Rene LeBlanc-Chaffin; Hong Chen; Stela S Palii; Kelly M Leach; Michael S Kilberg
The mechanism for transcriptional activation of the human ATA2 transporter gene by amino acid deprivation is different than that for asparagine synthetase.
The Journal of nutrition 2002;132(10):3023-9.
2002: Fai Siu; Perry J Bain; Rene LeBlanc-Chaffin; Hong Chen; Michael S Kilberg
ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene.
The Journal of biological chemistry 2002;277(27):24120-7.
2002: Michael S Kilberg; Ione P Barbosa-Tessmann
Genomic sequences necessary for transcriptional activation by amino acid deprivation of mammalian cells.
The Journal of nutrition 2002;132(7):1801-4.
2002: Van Leung-Pineda; Michael S Kilberg
Role of Sp1 and Sp3 in the nutrient-regulated expression of the human asparagine synthetase gene.
The Journal of biological chemistry 2002;277(19):16585-91.
2002: Se-Ho Chang; Ione P Barbosa-Tessmann; Chin Chen; Michael S Kilberg; Anupam Agarwal
Glucose deprivation induces heme oxygenase-1 gene expression by a pathway independent of the unfolded protein response.
The Journal of biological chemistry 2002;277(3):1933-40.
2002: Stuart Louis Cramer; Mark Beveridge; Michael S Kilberg; Donald A Novak
Physiological importance of system A-mediated amino acid transport to rat fetal development.
American journal of physiology. Cell physiology 2002;282(1):C153-60.
2001: Fai Siu; Chin Chen; Can Zhong; Michael S Kilberg
CCAAT/enhancer-binding protein-beta is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene.
The Journal of biological chemistry 2001;276(51):48100-7.
2001: Michael D Weiss; S Derazi; Michael S Kilberg; Kevin J Anderson
Ontogeny and localization of the neutral amino acid transporter ASCT1 in rat brain.
Brain research. Developmental brain research 2001;130(2):183-90.
2001: Ara Aslanian; Michael S Kilberg
Multiple adaptive mechanisms affect asparagine synthetase substrate availability in asparaginase-resistant MOLT-4 human leukaemia cells.
The Biochemical journal 2001;358(Pt 1):59-67.
2001: Ara Aslanian; B S Fletcher; Michael S Kilberg
Asparagine synthetase expression alone is sufficient to induce l-asparaginase resistance in MOLT-4 human leukaemia cells.
The Biochemical journal 2001;357(Pt 1):321-8.
2000: Ione P Barbosa-Tessmann; Chin Chen; Can Zhong; Fai Siu; Sheldon M Schuster; Harry S Nick; Michael S Kilberg
Activation of the human asparagine synthetase gene by the amino acid response and the endoplasmic reticulum stress response pathways occurs by common genomic elements.
The Journal of biological chemistry 2000;275(35):26976-85.
1999: James C Matthews; Mark Beveridge; E Dialynas; A Bartke; Michael S Kilberg; Donald A Novak
Placental anionic and cationic amino acid transporter expression in growth hormone overexpressing and null IGF-II or null IGF-I receptor mice.
Placenta 1999;20(8):639-50.
1999: Ione P Barbosa-Tessmann; Chin Chen; Can Zhong; Sheldon M Schuster; Harry S Nick; Michael S Kilberg
Activation of the unfolded protein response pathway induces human asparagine synthetase gene expression.
The Journal of biological chemistry 1999;274(44):31139-44.
1999: Ione P Barbosa-Tessmann; V L Pineda; Harry S Nick; Sheldon M Schuster; Michael S Kilberg
Transcriptional regulation of the human asparagine synthetase gene by carbohydrate availability.
The Biochemical journal 1999;339 ( Pt 1)():151-8.
1998: James C Matthews; Mark Beveridge; Malandro Marc; Michael S Kilberg; Donald A Novak
Response of placental amino acid transport to gestational age and intrauterine growth retardation.
The Proceedings of the Nutrition Society 1998;57(2):257-63.
1998: James C Matthews; Mark Beveridge; Malandro Marc; Jeffrey rothstein; Martha Campbell-Thompson; Jill W Verlander; Michael S Kilberg; Donald A Novak
Activity and protein localization of multiple glutamate transporters in gestation day 14 vs. day 20 rat placenta.
The American journal of physiology 1998;274(3 Pt 1):C603-14.
1997: James C Matthews; Ara Aslanian; KK McDonald; W Yang; Malandro Marc; Donald A Novak; Michael S Kilberg
An expression system for mammalian amino acid transporters using a stably maintained episomal vector.
Analytical biochemistry 1997;254(2):208-14.
1997: KK McDonald; Sergey Zharikov; Edward R Block; Michael S Kilberg
A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric-oxide synthase may explain the "arginine paradox".
The Journal of biological chemistry 1997;272(50):31213-6.
1997: Donald A Novak; James C Matthews; Mark Beveridge; S Y Yao; J Young; Michael S Kilberg
Demonstration of system y+L activity on the basal plasma membrane surface of rat placenta and developmentally regulated expression of 4F2HC mRNA.
Placenta 1997;18(8):643-8.
1997: R G Hutson; Toshiyuki Kitoh; D A Moraga Amador; S Cosic; Sheldon M Schuster; Michael S Kilberg
Amino acid control of asparagine synthetase: relation to asparaginase resistance in human leukemia cells.
The American journal of physiology 1997;272(5 Pt 1):C1691-9.
1997: B K Tamarappoo; Mohan K Raizada; Michael S Kilberg
Identification of a system N-like Na(+)-dependent glutamine transport activity in rat brain neurons.
Journal of neurochemistry 1997;68(3):954-60.
1997: KK McDonald; R Rouhani; Mary E Handlogten; Edward R Block; O W Griffith; R D Allison; Michael S Kilberg
Inhibition of endothelial cell amino acid transport System y+ by arginine analogs that inhibit nitric oxide synthase.
Biochimica et biophysica acta 1997;1324(1):133-41.
1996: R G Hutson; U Warskulat; D Häussinger; Michael S Kilberg
An example of nutrient control of gene expression: amino acid-dependent regulation of asparagine synthetase.
Clinical nutrition (Edinburgh, Scotland) 1996;15(6):327-31.
1996: Malandro Marc; Mark Beveridge; Donald A Novak; Michael S Kilberg
Rat placental amino acid transport after protein-deprivation-induced intrauterine growth retardation.
Biochemical Society transactions 1996;24(3):839-43.
1996: Malandro Marc; Mark Beveridge; Michael S Kilberg; Donald A Novak
Effect of low-protein diet-induced intrauterine growth retardation on rat placental amino acid transport.
The American journal of physiology 1996;271(1 Pt 1):C295-303.
1996: M E Handlogten; E E Dudenhausen; WEI YANG; Michael S Kilberg
Association of hepatic system A amino acid transporter with the membrane-cytoskeletal proteins ankyrin and fodrin.
Biochimica et biophysica acta 1996;1282(1):107-14.
1996: B K Tamarappoo; K K McDonald; Michael S Kilberg
Expressed human hippocampal ASCT1 amino acid transporter exhibits a pH-dependent change in substrate specificity.
Biochimica et biophysica acta 1996;1279(2):131-6.
1996: Malandro Marc; Michael S Kilberg
Molecular biology of mammalian amino acid transporters.
Annual review of biochemistry 1996;65():305-36.
1996: M Velaz-Faircloth; T S McGraw; M S alandro; robert fremeau; Michael S Kilberg; Kevin J Anderson
Characterization and distribution of the neuronal glutamate transporter EAAC1 in rat brain.
The American journal of physiology 1996;270(1 Pt 1):C67-75.
1996: R O Laine; R G Hutson; Michael S Kilberg
Eukaryotic gene expression: metabolite control by amino acids.
Progress in nucleic acid research and molecular biology 1996;53():219-48.
1994: R G Hutson; Michael S Kilberg
Cloning of rat asparagine synthetase and specificity of the amino acid-dependent control of its mRNA content.
The Biochemical journal 1994;304 ( Pt 3)():745-50.
1994: Malandro Marc; Mark Beveridge; Michael S Kilberg; Donald A Novak
Ontogeny of cationic amino acid transport systems in rat placenta.
The American journal of physiology 1994;267(3 Pt 1):C804-11.
1994: B K Tamarappoo; H P Singh; Michael S Kilberg
Protein modification of glutamine transporters in SV40-transformed hepatocytes and immunodetection of proteins associated with hepatic system N transport activity.
The Journal of nutrition 1994;124(8 Suppl):1493S-1498S.
1994: Donald A Novak; Michael S Kilberg; Mark Beveridge
Ontogeny and plasma-membrane domain localization of amino acid transport system L in rat liver.
The Biochemical journal 1994;301 ( Pt 3)():671-4.
1994: M H Woodard; William A Dunn; R O Laine; Malandro Marc; R McMahon; O Simell; Edward R Block; Michael S Kilberg
Plasma membrane clustering of system y+ (CAT-1) amino acid transporter as detected by immunohistochemistry.
The American journal of physiology 1994;266(5 Pt 1):E817-24.
1994: R O Laine; Neil F Shay; Michael S Kilberg
Nuclear retention of the induced mRNA following amino acid-dependent transcriptional regulation of mammalian ribosomal proteins L17 and S25.
The Journal of biological chemistry 1994;269(13):9693-7.
1994: Michael S Kilberg; R G Hutson; R O Laine
Amino acid-regulated gene expression in eukaryotic cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1994;8(1):13-9.
1993: S Shafqat; B K Tamarappoo; Michael S Kilberg; Ram S Puranam; James O McNamara; A Guadaño-Ferraz; robert fremeau
Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters.
The Journal of biological chemistry 1993;268(21):15351-5.
1993: T C Chiles; R O Laine; Neil F Shay; M E Handlogten; Harry S Nick; Michael S Kilberg
Enhanced mRNA content in response to amino acid starvation for a 73 kDa protein of the inner mitochondrial membrane.
Biochemical and biophysical research communications 1993;193(3):1068-75.
1993: B K Tamarappoo; M Nam; Michael S Kilberg; TC Welbourne
Glucocorticoid regulation of splanchnic glutamine, alanine, glutamate, ammonia, and glutathione fluxes.
The American journal of physiology 1993;264(4 Pt 1):E526-33.
1993: Michael S Kilberg; Bruce R Stevens; Donald A Novak
Recent advances in mammalian amino acid transport.
Annual review of nutrition 1993;13():137-65.
1992: Rohit Cariappa; Michael S Kilberg
Plasma membrane domain localization and transcytosis of the glucagon-induced hepatic system A carrier.
The American journal of physiology 1992;263(6 Pt 1):E1021-8.
1992: B K Tamarappoo; M E Handlogten; R O Laine; Maria A Serrano; J Dugan; Michael S Kilberg
Identification of the protein responsible for hepatic system N amino acid transport activity.
The Journal of biological chemistry 1992;267(4):2370-4.
1991: R O Laine; Philip J Laipis; Neil F Shay; Michael S Kilberg
Identification of an amino acid-regulated mRNA from rat liver as the mammalian equivalent of bacterial ribosomal protein L22.
The Journal of biological chemistry 1991;266(26):16969-72.
1991: S W Wilde; Michael S Kilberg
Glutamine transport by basolateral plasma-membrane vesicles prepared from rabbit intestine.
The Biochemical journal 1991;277 ( Pt 3)():687-91.
1991: B P Bode; Michael S Kilberg
Amino acid-dependent increase in hepatic system N activity is linked to cell swelling.
The Journal of biological chemistry 1991;266(12):7376-81.
1991: B K Tamarappoo; Michael S Kilberg
Functional reconstitution of the hepatic system N amino acid transport activity.
The Biochemical journal 1991;274 ( Pt 1)():97-101.
1990: Neil F Shay; Harry S Nick; Michael S Kilberg
Molecular cloning of an amino acid-regulated mRNA (amino acid starvation-induced) in rat hepatoma cells.
The Journal of biological chemistry 1990;265(29):17844-8.
1990: M E Mailliard; Michael S Kilberg
Sodium-dependent neutral amino acid transport by human liver plasma membrane vesicles.
The Journal of biological chemistry 1990;265(24):14321-6.
1990: Roy W Tarnuzzer; M J Campa; N X Qian; E Englesberg; Michael S Kilberg
Expression of the mammalian system A neutral amino acid transporter in Xenopus oocytes.
The Journal of biological chemistry 1990;265(23):13914-7.
1990: B Bode; B K Tamarappoo; M Mailliard; Michael S Kilberg
Characteristics and regulation of hepatic glutamine transport.
JPEN. Journal of parenteral and enteral nutrition 1990;14(4 Suppl):51S-55S.
1990: A D Fong; M E Handlogten; Michael S Kilberg
Substrate-dependent adaptive regulation and trans-inhibition of System A-mediated amino acid transport. Studies using rat hepatoma plasma membrane vesicles.
Biochimica et biophysica acta 1990;1022(3):325-32.
1990: Rohit Cariappa; Michael S Kilberg
Hormone-induced system A amino acid transport activity in rat liver plasma membrane and Golgi vesicles. Evidence for a differential sensitivity to inactivation by N-ethylmaleimide during carrier maturation.
The Journal of biological chemistry 1990;265(3):1470-5.
1989: M J Campa; Michael S Kilberg
Characterization of neutral and cationic amino acid transport in Xenopus oocytes.
Journal of cellular physiology 1989;141(3):645-52.
1989: P Fafournoux; E E Dudenhausen; Michael S Kilberg
Solubilization and reconstitution characteristics of hepatic system A-mediated amino acid transport.
The Journal of biological chemistry 1989;264(9):4805-11.
1988: T C Chiles; K L Dudeck-Collart; Michael S Kilberg
Inactivation of amino acid transport in rat hepatocytes and hepatoma cells by PCMBS.
The American journal of physiology 1988;255(3 Pt 1):C340-5.
1988: M E Handlogten; Michael S Kilberg
Growth-dependent regulation of system A in SV40-transformed fetal rat hepatocytes.
The American journal of physiology 1988;255(3 Pt 1):C261-70.
1988: Michael S Kilberg; M E Handlogten
Transport of branched-chain amino acids and their corresponding 2-keto acids by mammalian cells.
Methods in enzymology 1988;166():252-60.
1987: K L Dudeck; E E Dudenhausen; T C Chiles; P Fafournoux; Michael S Kilberg
Evidence for inherent differences in the system A carrier from normal and transformed liver tissue. Differential inactivation and substrate protection in membrane vesicles and reconstituted proteoliposomes.
The Journal of biological chemistry 1987;262(26):12565-9.
1987: T C Chiles; T W O'Brien; Michael S Kilberg
Production of monospecific antibodies to a low-abundance hepatic membrane protein using nitrocellulose immobilized protein as antigen.
Analytical biochemistry 1987;163(1):136-42.
1987: D S Bracy; Mark A Schenerman; Michael S Kilberg
Solubilization and reconstitution of hepatic System A-mediated amino acid transport. Preparation of proteoliposomes containing glucagon-stimulated transport activity.
Biochimica et biophysica acta 1987;899(1):51-8.
1986: T C Chiles; Michael S Kilberg
System A transport activity in normal rat hepatocytes and transformed liver cells: substrate protection from inactivation by sulfhydryl-modifying reagents.
Journal of cellular physiology 1986;129(3):321-8.
1986: Mark A Schenerman; Michael S Kilberg
Maintenance of glucagon-stimulated system A amino acid transport activity in rat liver plasma membrane vesicles.
Biochimica et biophysica acta 1986;856(3):428-36.
1986: D S Bracy; M E Handlogten; E F Barber; H P Han; Michael S Kilberg
Cis-inhibition, trans-inhibition, and repression of hepatic amino acid transport mediated by System A. Substrate specificity and other properties.
The Journal of biological chemistry 1986;261(4):1514-20.
1985: Michael S Kilberg; H P Han; E F Barber; T C Chiles
Adaptive regulation of neutral amino acid transport System A in rat H4 hepatoma cells.
Journal of cellular physiology 1985;122(2):290-8.
1985: Michael S Kilberg; E F Barber; M E Handlogten
Characteristics and hormonal regulation of amino acid transport system A in isolated rat hepatocytes.
Current topics in cellular regulation 1985;25():133-63.
1984: M E Handlogten; Michael S Kilberg
Induction and decay of amino acid transport in the liver. Turnover of transport activity in isolated hepatocytes after stimulation by diabetes or glucagon.
The Journal of biological chemistry 1984;259(6):3519-25.
1983: E F Barber; M E Handlogten; Michael S Kilberg
Induction of amino acid transport system A in rat hepatocytes is blocked by tunicamycin.
The Journal of biological chemistry 1983;258(19):11851-5.
1983: Michael S Kilberg; Thomas Vida; E F Barber
Regulation of neutral amino acid transport in hepatocytes isolated from adrenalectomized rats.
Journal of cellular physiology 1983;114(1):45-52.
1982: E F Barber; M E Handlogten; Thomas Vida; Michael S Kilberg
Neutral amino acid transport in hepatocytes isolated from streptozotocin-induced diabetic rats.
The Journal of biological chemistry 1982;257(24):14960-7.
1982: L Weissbach; M E Handlogten; H N Christensen; Michael S Kilberg
Evidence for two Na+-independent neutral amino acid transport systems in primary cultures of rat hepatocytes. Time-dependent changes in activity.
The Journal of biological chemistry 1982;257(20):12006-11.
1982: M E Handlogten; Michael S Kilberg
Transport system a is not responsive to hormonal stimulation in primary cultures of fetal rat hepatocytes.
Biochemical and biophysical research communications 1982;108(3):1113-9.
1982: M E Handlogten; L Weissbach; Michael S Kilberg
Heterogeneity of Na+-independent 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid and L-leucine transport in isolated rat hepatocytes in primary culture.
Biochemical and biophysical research communications 1982;104(1):307-13.
1982: M E Handlogten; Michael S Kilberg; H N Christensen
Incomplete correspondence between repressive and substrate action by amino acids on transport systems A and N in monolayered rat hepatocytes.
The Journal of biological chemistry 1982;257(1):345-8.
1981: Michael S Kilberg; M E Handlogten; H N Christensen
Characteristics of system ASC for transport of neutral amino acids in the isolated rat hepatocyte.
The Journal of biological chemistry 1981;256(7):3304-12.
1980: Michael S Kilberg; M E Handlogten; H N Christensen
Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs.
The Journal of biological chemistry 1980;255(9):4011-9.