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Chaekyun Kim

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In Soon Kang; Chaekyun Kim
Taurine chloramine administered in vivo increases NRF2-regulated antioxidant enzyme expression in murine peritoneal macrophages.
Kyoung Soo Kim; So-Mi Kim; Sang-Hoon Lee; Yeon-Ah Lee; Ran Song; Hyung-In Yang; Myung Chul Yoo; Hyun-Mi Choi; Hye-In Ji; Chaekyun Kim; Jung Yeon Kim; Seung-Jae Hong
Effect of taurine chloramine on differentiation of human preadipocytes into adipocytes.
Yutie Wang; Kyoung Soo Kim; Young-Nam Cha; Chaekyun Kim
Taurine chloramine inhibits osteoclastogenesis and splenic lymphocyte proliferation in mice with collagen-induced arthritis.

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All Publications

2013: In Soon Kang; Chaekyun Kim
Taurine chloramine administered in vivo increases NRF2-regulated antioxidant enzyme expression in murine peritoneal macrophages.
Advances in experimental medicine and biology 2013;775():259-67.
2013: Kyoung Soo Kim; So-Mi Kim; Sang-Hoon Lee; Yeon-Ah Lee; Ran Song; Hyung-In Yang; Myung Chul Yoo; Hyun-Mi Choi; Hye-In Ji; Chaekyun Kim; Jung Yeon Kim; Seung-Jae Hong
Effect of taurine chloramine on differentiation of human preadipocytes into adipocytes.
Advances in experimental medicine and biology 2013;775():247-57.
2011: Yutie Wang; Kyoung Soo Kim; Young-Nam Cha; Chaekyun Kim
Taurine chloramine inhibits osteoclastogenesis and splenic lymphocyte proliferation in mice with collagen-induced arthritis.
European journal of pharmacology 2011;668(1-2):325-30.
2011: Shuyu Piao; Young-Nam Cha; Chaekyun Kim
Taurine chloramine protects RAW 264.7 macrophages against hydrogen peroxide-induced apoptosis by increasing antioxidants.
Journal of clinical biochemistry and nutrition 2011;49(1):50-6.
2011: Abel Sanchez-Aguilera; David T Scadden; Kristina Brumme; Adrienne Dorrance; Francesca Ferraro; Chaekyun Kim; Yun-Jung Lee; Cristina Lo Celso; Hongbo R Luo; Subhanjan Mondal; David A Williams
Guanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(23):9607-12.
2010: Chaekyun Kim; Jin Sun Jang; Mi-Ran Cho; Santosh R Agarawal; Young-Nam Cha
Taurine chloramine induces heme oxygenase-1 expression via Nrf2 activation in murine macrophages.
International immunopharmacology 2010;10(4):440-6.
2010: Sung-Yun Pai; Chaekyun Kim; David A Williams
Rac GTPases in human diseases.
Disease markers 2010;29(3-4):177-87.
2010: Kyoung Soo Kim; Hyun-Mi Choi; Da Hee Oh; Chaekyun Kim; Jin Seok Jeong; Myung Chul Yoo; Hyung-In Yang
Effect of taurine chloramine on the production of matrix metalloproteinases (MMPs) in adiponectin- or IL-1beta-stimulated fibroblast-like synoviocytes.
Journal of biomedical science 2010;17 Suppl 1():S27.
2009: Jin Sun Jang; Shuyu Piao; Young-Nam Cha; Chaekyun Kim
Taurine Chloramine Activates Nrf2, Increases HO-1 Expression and Protects Cells from Death Caused by Hydrogen Peroxide.
Journal of clinical biochemistry and nutrition 2009;45(1):37-43.
2009: Chae-Man Lim; Seung-Woo Kim; Ju-Young Park; Chaekyun Kim; Sung Hwa Yoon; Ja-Kyeong Lee
Fluoxetine affords robust neuroprotection in the postischemic brain via its anti-inflammatory effect.
Journal of neuroscience research 2009;87(4):1037-45.
2009: Chaekyun Kim; Seongtag Kim
Taurine chloramine inhibits LPS-induced glucose uptake and glucose transporter 1 expression in RAW 264.7 macropages.
Advances in experimental medicine and biology 2009;643():473-80.
2009: Chaekyun Kim; Young-Nam Cha
Production of reactive oxygen and nitrogen species in phagocytes is regulated by taurine chloramine.
Advances in experimental medicine and biology 2009;643():463-72.
2007: Yu Li; Jingliang Yan; Pradip De; Hua-Chen Chang; Akira Yamauchi; Kent W Christopherson; Nivanka C Paranavitana; Xiaodong Peng; Chaekyun Kim; Veerendra Munugalavadla; Veerendra Munugulavadla; Reuben Kapur; Hanying Chen; Weinian Shou; James C Stone; Mark H Kaplan; Mary C Dinauer; Donald L Durden; Lawrence A Quilliam
Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(12):8322-31.
2007: Kyoung Soo Kim; Eun-Kyung Park; Seung Min Ju; Hye-Sook Jung; Jun Soo Bang; Chaekyun Kim; Yeon-Ah Lee; Seung-Jae Hong; Sang-Hoon Lee; Hyung-In Yang; Myung Chul Yoo
Taurine chloramine differentially inhibits matrix metalloproteinase 1 and 13 synthesis in interleukin-1beta stimulated fibroblast-like synoviocytes.
Arthritis research & therapy 2007;9(4):R80.
2006: Hyung Sim Choi; Young-Nam Cha; Chaekyun Kim
Taurine chloramine inhibits PMA-stimulated superoxide production in human neutrophils perhaps by inhibiting phosphorylation and translocation of p47(phox).
International immunopharmacology 2006;6(9):1431-40.
2006: Klaokwan Srisook; Shan-Shu Han; Hyung-Sim Choi; Mei-Hua Li; Hideo Ueda; Chaekyun Kim; Young-Nam Cha
CO from enhanced HO activity or from CORM-2 inhibits both O2- and NO production and downregulates HO-1 expression in LPS-stimulated macrophages.
Biochemical pharmacology 2006;71(3):307-18.
2006: Chaekyun Kim; Hyung Sim Choi; Jun Woo Kim
Taurine chloramine inhibits the production of nitric oxide and superoxide anion by modulating specific mitogen-activated protein kinases.
Advances in experimental medicine and biology 2006;583():493-8.
2006: Chaekyun Kim
Accumulation of taurine in tumor and inflammatory lesions.
Advances in experimental medicine and biology 2006;583():213-7.
2006: Virginia M Meade; Cecilia N Barese; Chaekyun Kim; Charles G Njinimbam; Christophe C Marchal; David A Ingram; D Wade Clapp; Mary C Dinauer; Mervin C Yoder
Rac2 concentrations in umbilical cord neutrophils.
Biology of the neonate 2006;90(3):156-9.
2006: Hyung Sim Choi; Jun Woo Kim; Young-Nam Cha; Chaekyun Kim
A quantitative nitroblue tetrazolium assay for determining intracellular superoxide anion production in phagocytic cells.
Journal of immunoassay & immunochemistry 2006;27(1):31-44.
2006: Chaekyun Kim; Mary C Dinauer
Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid.
Journal of leukocyte biology 2006;79(1):223-34.
2005: Klaokwan Srisook; Chaekyun Kim; Young-Nam Cha
Molecular mechanisms involved in enhancing HO-1 expression: de-repression by heme and activation by Nrf2, the "one-two" punch.
Antioxidants & redox signaling 2005;7(11-12):1674-87.
2005: Jun Woo Kim; Chaekyun Kim
Inhibition of LPS-induced NO production by taurine chloramine in macrophages is mediated though Ras-ERK-NF-kappaB.
Biochemical pharmacology 2005;70(9):1352-60.
2005: Klaokwan Srisook; Chaekyun Kim; Young-Nam Cha
Cytotoxic and cytoprotective actions of O2- and NO (ONOO-) are determined both by cellular GSH level and HO activity in macrophages.
Methods in enzymology 2005;396():414-24.
2005: Klaokwan Srisook; Chaekyun Kim; Young-Nam Cha
Role of NO in enhancing the expression of HO-1 in LPS-stimulated macrophages.
Methods in enzymology 2005;396():368-77.
2004: Akira Yamauchi; Chaekyun Kim; Shijun Li; Christophe C Marchal; Jason Towe; Simon J Atkinson; Mary C Dinauer
Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):5971-9.
2003: Chaekyun Kim; Christophe C Marchal; Josef M Penninger; Mary C Dinauer
The hemopoietic Rho/Rac guanine nucleotide exchange factor Vav1 regulates N-formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(8):4425-30.
2001: Chaekyun Kim; Phillip S Brereton; MF Verhagen; Michael W W Adams
Ferredoxin from Pyrococcus furiosus.
Methods in enzymology 2001;334():30-40.
2001: Michael W W Adams; James F Holden; Angeli Lal Menon; Gerrit J Schut; Amy M Grunden; C Hou; AM Hutchins; Francis E Jenney; Chaekyun Kim; Kesen Ma; Guangliang Pan; Roopali Roy; Rajat Sapra; Sherry V Story; MF Verhagen
Key role for sulfur in peptide metabolism and in regulation of three hydrogenases in the hyperthermophilic archaeon Pyrococcus furiosus.
Journal of bacteriology 2001;183(2):716-24.
2000: David A Williams; W Tao; F Yang; Chaekyun Kim; Yi Gu; P Mansfield; John E Levine; B Petryniak; CW Derrow; C Harris; B Jia; Y Zheng; D R Ambruso; J B Lowe; Simon J Atkinson; Mary C Dinauer; Laurence A Boxer
Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency.
Blood 2000;96(5):1646-54.
2000: Feng-Chun Yang; Reuben Kapur; AJ King; W Tao; Chaekyun Kim; Jovencio Borneo; Robert Breese; M Marshall; Mary C Dinauer; David A Williams
Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells.
Immunity 2000;12(5):557-68.
1999: Chaekyun Kim; C A Woodward; E N Kaufman; Michael W W Adams
Stability and sulfur-reduction activity in non-aqueous phase liquids of the hydrogenase from the hyperthermophile Pyrococcus furiosus.
Biotechnology and bioengineering 1999;65(1):108-13.
1999: Andrew W Roberts; Chaekyun Kim; Lijie Zhen; J B Lowe; Reuben Kapur; B Petryniak; A Spaetti; Jonathan D Pollock; Jovencio Borneo; G B Bradford; Simon J Atkinson; Mary C Dinauer; David A Williams
Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense.
Immunity 1999;10(2):183-96.
1998: Chaekyun Kim; J K Chung; J M Jeong; Y S Chang; Y J Lee; Y J Kim; M C Lee; C S Koh; B K Kim
Uptake of taurine and taurine chloramine in murine macrophages and their distribution in mice with experimental inflammation.
Advances in experimental medicine and biology 1998;442():169-76.