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Dae-Kee Kim

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Eun-Young Kim; Jin Hyoung Kim; Edward W Lee; Yong Fan; Dae-Kee Kim; Sangsoo Park; Ho-Young Song; Han Kyu Na
IN-1233-eluting Covered Metallic Stent to Prevent Hyperplasia: Experimental Study in a Rabbit Esophageal Model.
Hye-Lin Kim; Younghwa Na; Yongmun Choi; Kyung-Hwa Jeon; Kyu-Yeon Jun; Dae-Kee Kim; Youngjoo Kwon
A-62176, a potent topoisomerase inhibitor, inhibits the expression of human epidermal growth factor receptor 2.
Maddeboina Krishnaiah; Hyun-Ju Park; Kota Sudhakar Rao; Yhun Yhong Sheen; Do-Hyun Son; Domalapally Sreenu; Vura Bala Subrahmanyam; Cheng Hua Jin; Seung Won Kim; Dae-Kee Kim
Synthesis and biological evaluation of 2-benzylamino-4(5)-(6-methylpyridin-2-yl)-5(4)-([1,2,4]triazolo[1,5-a]-pyridin-6-yl)thiazoles as transforming growth factor-β type 1 receptor kinase inhibitors.

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2013: Eun-Young Kim; Jin Hyoung Kim; Edward W Lee; Yong Fan; Dae-Kee Kim; Sangsoo Park; Ho-Young Song; Han Kyu Na
IN-1233-eluting Covered Metallic Stent to Prevent Hyperplasia: Experimental Study in a Rabbit Esophageal Model.
Radiology 2013;267(2):396-404.
2012: Hye-Lin Kim; Younghwa Na; Yongmun Choi; Kyung-Hwa Jeon; Kyu-Yeon Jun; Dae-Kee Kim; Youngjoo Kwon
A-62176, a potent topoisomerase inhibitor, inhibits the expression of human epidermal growth factor receptor 2.
Cancer letters 2012;325(1):72-9.
2012: Maddeboina Krishnaiah; Hyun-Ju Park; Kota Sudhakar Rao; Yhun Yhong Sheen; Do-Hyun Son; Domalapally Sreenu; Vura Bala Subrahmanyam; Cheng Hua Jin; Seung Won Kim; Dae-Kee Kim
Synthesis and biological evaluation of 2-benzylamino-4(5)-(6-methylpyridin-2-yl)-5(4)-([1,2,4]triazolo[1,5-a]-pyridin-6-yl)thiazoles as transforming growth factor-β type 1 receptor kinase inhibitors.
European journal of medicinal chemistry 2012;57():74-84.
2012: Kyung Nan Min; Ki Eun Joung; Dae-Kee Kim; Yhun Y Sheen
Anti-Cancer Effect of 3-(4-dimethylamino phenyl)-N-hydroxy-2-propenamide in MCF-7 Human Breast Cancer.
Environmental health and toxicology 2012;27():e2012010.
2011: Chul-Yong Park; Cheng Hua Jin; Dae-Kee Kim; Jeong-Suk Nam; Jee-Yeon Son; Yhun Yhong Sheen
EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung.
European journal of cancer (Oxford, England : 1990) 2011;47(17):2642-53.
2011: Cheng Hua Jin; Maddeboina Krishnaiah; Annaji Venkata Nagendra Mohan; Chul-Yong Park; Kota Sudhakar Rao; Yhun Yhong Sheen; Jee-Yeon Son; Domalapally Sreenu; Vura Bala Subrahmanyam; Dae-Kee Kim
Synthesis and biological evaluation of 1-substituted-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors.
Bioorganic & medicinal chemistry letters 2011;21(20):6049-53.
2011: Cheng Hua Jin; Maddeboina Krishnaiah; Annaji Venkata Nagendra Mohan; Chul-Yong Park; Hyun-Ju Park; Kota Sudhakar Rao; Yhun Yhong Sheen; Do-Hyun Son; Jee-Yeon Son; Domalapally Sreenu; Vura Bala Subrahmanyam; Dae-Kee Kim
Synthesis and biological evaluation of 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors.
European journal of medicinal chemistry 2011;46(9):3917-25.
2011: Hyun-Jung Yoon; Kang-Sun Hong; Jin Hyoung Kim; Yeon Joo Kim; Hyung Gyu Park; Ho-Young Song; Dae-Kee Kim
Role of IN-1233 in the prevention of neointimal hyperplasia after stent placement in a rat artery model.
Journal of vascular and interventional radiology : JVIR 2011;22(9):1321-8.
2011: Chul Hee Lee; J Y Lee; Sang-Min Lee; K Y Lim; C M Park; Hee Sun Chung; Sung Koo Han; S-S Hwang; D J Kim; Dae-Kee Kim; Hyeoung-Joon Kim; Young-Woo Kim; S-C Yang; J H Yeon; Jae-Joon Yim; Chul-Gyu Yoo; Young-Soo Shim
The impact of combined pulmonary fibrosis and emphysema on mortality.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2011;15(8):1111-6.
2011: Ashwini Katre; Dae-Kee Kim; Hasina Akhter; Carol A Ballinger; Michelle V Fanucchi; Edward M Postlethwait; Rui-Ming Liu
Increased transforming growth factor beta 1 expression mediates ozone-induced airway fibrosis in mice.
Inhalation toxicology 2011;23(8):486-94.
2011: Cheng Hua Jin; Maddeboina Krishnaiah; Domalapally Sreenu; Kota Sudhakar Rao; Vura Bala Subrahmanyam; Chul-Yong Park; Jee-Yeon Son; Yhun Yhong Sheen; Dae-Kee Kim
Synthesis and biological evaluation of 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinolin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors.
Bioorganic & medicinal chemistry 2011;19(8):2633-40.
2011: J S Park; Chul Hee Lee; Jae-Joon Yim; S-C Yang; Chul-Gyu Yoo; Hee Sun Chung; Young-Woo Kim; Sung Koo Han; Young-Soo Shim; Dae-Kee Kim
Impact of antibiotic prophylaxis on postbronchoscopy fever: a randomised controlled study.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2011;15(4):528-35.
2010: Purushottam M Dewang; Dae-Kee Kim
Synthesis and biological evaluation of 2-pyridyl-substituted pyrazoles and imidazoles as transforming growth factor-beta type 1 receptor kinase inhibitors.
Bioorganic & medicinal chemistry letters 2010;20(14):4228-32.
2010: Dae-Kee Kim; Yeon-Im Lee; Yeon Woo Lee; Purushottam M Dewang; Yhun Yhong Sheen; Yeo Woon Kim; Hyun-Ju Park; Jakyung Yoo; Ho Soon Lee; Yong-Kook Kim
Synthesis and biological evaluation of 4(5)-(6-methylpyridin-2-yl)imidazoles and -pyrazoles as transforming growth factor-beta type 1 receptor kinase inhibitors.
Bioorganic & medicinal chemistry 2010;18(12):4459-67.
2010: Jin Hyoung Kim; Ho-Young Song; Jung-Hoon Park; Hyun-Jung Yoon; Hyung Gyu Park; Dae-Kee Kim
IN-1233, an ALK-5 inhibitor: prevention of granulation tissue formation after bare metallic stent placement in a rat urethral model.
Radiology 2010;255(1):75-82.
2010: Hyeoung-Joon Kim; Chul Hee Lee; S Shin; Je-Ho Lee; Young-Woo Kim; Hee Sun Chung; Sung Koo Han; Young-Soo Shim; Dae-Kee Kim
The impact of nutritional deficit on mortality of in-patients with pulmonary tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2010;14(1):79-85.
2009: Ji-Kan Ryu; Shuguang Piao; Hwa-Yean Shin; Min Ji Choi; Lu Wei Zhang; Hai-Rong Jin; Woo Jean Kim; Jee-Young Han; Soon Sun Hong; Seok Hee Park; Sang-Jin Lee; In-Hoo Kim; Chung Ryul Lee; Dae-Kee Kim; Mizuko Mamura; Seong-Jin Kim; Jun-Kyu Suh
IN-1130, a novel transforming growth factor-beta type I receptor kinase (activin receptor-like kinase 5) inhibitor, promotes regression of fibrotic plaque and corrects penile curvature in a rat model of Peyronie's disease.
The journal of sexual medicine 2009;6(5):1284-96.
2009: Lu Long; Alexi Crosby; Xudong Yang; Mark Southwood; Paul D Upton; Dae-Kee Kim; Nicholas W Morrell
Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease.
Circulation 2009;119(4):566-76.
2009: Dae-Kee Kim; Sun Hee Jung; Ho Soon Lee; Purushottam M Dewang
Synthesis and biological evaluation of benzenesulfonamide-substituted 4-(6-alkylpyridin-2-yl)-5-(quinoxalin-6-yl)imidazoles as transforming growth factor-beta type 1 receptor kinase inhibitors.
European journal of medicinal chemistry 2009;44(2):568-76.
2008: Geun Taek Lee; Jun Hyuk Hong; Thomas J Mueller; John A Watson; Cheol Kwak; Youn Young Sheen; Dae-Kee Kim; Seong Jin Kim; Isaac Yi Kim
Effect of IN-1130, a small molecule inhibitor of transforming growth factor-beta type I receptor/activin receptor-like kinase-5, on prostate cancer cells.
The Journal of urology 2008;180(6):2660-7.
2008: Dae-Kee Kim; Jin-Hwi Lim; Jung A Lee; Purushottam M Dewang
Synthesis and biological evaluation of trisubstituted imidazole derivatives as inhibitors of p38alpha mitogen-activated protein kinase.
Bioorganic & medicinal chemistry letters 2008;18(14):4006-10.
2008: Y W Kim; Y K Kim; Dae-Kee Kim; Yhun Y Sheen
Identification of human cytochrome P450 enzymes involved in the metabolism of IN-1130, a novel activin receptor-like kinase-5 (ALK5) inhibitor.
Xenobiotica; the fate of foreign compounds in biological systems 2008;38(5):451-64.
2008: Dae-Kee Kim; Joon Hun Choi; Young Jae An; Ho Soon Lee
Synthesis and biological evaluation of 5-(pyridin-2-yl)thiazoles as transforming growth factor-beta type1 receptor kinase inhibitors.
Bioorganic & medicinal chemistry letters 2008;18(6):2122-7.
2008: Jung-Hyun Park; Hyun-Soon Jong; Sang Gyun Kim; Yeonjoo Jung; Keun-Wook Lee; JU-HEE LEE; Dae-Kee Kim; Yung-Jue Bang; Tae-You Kim
Inhibitors of histone deacetylases induce tumor-selective cytotoxicity through modulating Aurora-A kinase.
Journal of molecular medicine (Berlin, Germany) 2008;86(1):117-28.
2007: Jian Luo; Peggy P Ho; Marion Buckwalter; Tiffany Hsu; Lowen Y Lee; Hui Zhang; Dae-Kee Kim; Seong-Jin Kim; Sanjiv S Gambhir; Lawrence Steinman; Tony Wyss-Coray
Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis.
The Journal of clinical investigation 2007;117(11):3306-15.
2007: Beom Soo Shin; Seul Ki Hu; John Kim; Joon Gyo Oh; Won-No Youn; Bongyong Lee; Key An Um; Dae-Kee Kim; Ju Young Lee; Sun Dong Yoo
Development of LC/MS/MS assay for the determination of 5-ethyl-2-{5-[4-(2-hydroxyethyl)piperazine-1-sulfonyl]-2-propoxyphenyl}-7-propyl-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one (SK3530) in human plasma: application to a clinical pharmacokinetic study.
Journal of pharmaceutical and biomedical analysis 2007;45(1):176-84.
2007: Jakyung Yoo; Khac-Minh THAI; Dae-Kee Kim; Ju Young Lee; Hyun-Ju Park
3D-QSAR studies on sildenafil analogues, selective phosphodiesterase 5 inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(15):4271-4.
2007: Dae-Kee Kim; Yoojeung Jang; Ho Soon Lee; Hyun-Ju Park; Jakyung Yoo
Synthesis and biological evaluation of 4(5)-(6-alkylpyridin-2-yl)imidazoles as transforming growth factor-beta type 1 receptor kinase inhibitors.
Journal of medicinal chemistry 2007;50(13):3143-7.
2006: Ki Eun Joung; Kyung N Min; Jin Y An; Dae-Kee Kim; Gu Kong; Yhun Y Sheen
Potent in vivo anti-breast cancer activity of IN-2001, a novel inhibitor of histone deacetylase, in MMTV/c-Neu mice.
Cancer research 2006;66(10):5394-402.
2004: Jae Min Jeong; Jaetae Lee; Chang Hum Paik; Dae-Kee Kim; Dong Soo Lee; June-Key Chung; Myung Chul Lee
Site-specific 99mTc-labeling of antibody using dihydrazinophthalazine (DHZ) conjugation to Fc region of heavy chain.
Archives of pharmacal research 2004;27(9):961-7.
2004: Jung-Hyun Park; Yeonjoo Jung; Tai Young Kim; Sang Gyun Kim; Hyun-Soon Jong; Jung Weon Lee; Dae-Kee Kim; Jong-Soo Lee; Noe Kyeong Kim; Tae-You Kim; Yung-Jue Bang
Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(15):5271-81.
2004: Ki Eun Joung; Dae-Kee Kim; Yhun Y Sheen
Antiproliferative effect of trichostatin A and HC-toxin in T47D human breast cancer cells.
Archives of pharmacal research 2004;27(6):640-5.
2004: Dae-Kee Kim; Joonseop Kim; Hyun-Ju Park
Synthesis and biological evaluation of novel 2-pyridinyl-[1,2,3]triazoles as inhibitors of transforming growth factor beta 1 type 1 receptor.
Bioorganic & medicinal chemistry letters 2004;14(10):2401-5.
2004: Dae-Kee Kim; Ju Young Lee; Hyun-Ju Park; Khac-Minh THAI
Synthesis and phosphodiesterase 5 inhibitory activity of new sildenafil analogues containing a phosphonate group in the 5(')-sulfonamide moiety of phenyl ring.
Bioorganic & medicinal chemistry letters 2004;14(9):2099-103.
2004: Kyung Nan Min; Min Jung Cho; Dae-Kee Kim; Yhun Y Sheen
Estrogen receptor enhances the antiproliferative effects of trichostatin A and HC-toxin in human breast cancer cells.
Archives of pharmacal research 2004;27(5):554-61.
2004: Dae-Kee Kim; Joonseop Kim; Hyun-Ju Park
Design, synthesis, and biological evaluation of novel 2-pyridinyl-[1,2,4]triazoles as inhibitors of transforming growth factor beta1 type 1 receptor.
Bioorganic & medicinal chemistry 2004;12(9):2013-20.
2004: Hea Ok Kim; Hye Won Baek; Hyung Ryong Moon; Dae-Kee Kim; Moon Woo Chun; Lak Shin Jeong
Synthesis and biological evaluation of novel tert-azido or tert-amino substituted penciclovir analogs.
Organic & biomolecular chemistry 2004;2(8):1164-8.
2004: Mee Ryung Ahn; Dae-Kee Kim; Yhun Y Sheen
Trichostatin A, a histone deacetylase inhibitor stimulate CYP3A4 proximal promoter activity in Hepa-I cells.
Archives of pharmacal research 2004;27(4):415-21.
2004: Ja Young Kim; Mee Ryung Ahn; Dae-Kee Kim; Yhun Y Sheen
Histone deacetylase inhibitor stimulate CYP3A4 proximal promoter activity in HepG2 cells.
Archives of pharmacal research 2004;27(4):407-14.
2004: Dong Zhe Jin; Sung Hee Kwon; Hyung Ryong Moon; Prashantha Gunaga; Hea Ok Kim; Dae-Kee Kim; Moon Woo Chun; Lak Shin Jeong
Synthesis of D- and L-apio nucleoside analogues with 2'-hydroxyl group as potential anti-HIV agents.
Bioorganic & medicinal chemistry 2004;12(5):1101-9.
2003: Dae-Kee Kim; Ju Young Lee; Jae-Sun Kim; Je-Ho Ryu; Jin-Young Choi; Jun Won Lee; Guang-Jin Im; Tae-Kon Kim; Jung Woo Seo; Hyun-Ju Park; Jakyung Yoo; Jung-Hyun Park; Tae-You Kim; Yung-Jue Bang
Synthesis and biological evaluation of 3-(4-substituted-phenyl)-N-hydroxy-2-propenamides, a new class of histone deacetylase inhibitors.
Journal of medicinal chemistry 2003;46(26):5745-51.
2003: Saeyoung Park; Yoon Lim; Daeyeon Lee; Bomsoo Cho; Yung-Jue Bang; Sookwhan Sung; Hae-Yeong Kim; Dae-Kee Kim; Yun-Sil Lee; YeongWook Song; Doo-Il Jeoung
Identification and characterization of a novel cancer/testis antigen gene CAGE-1.
Biochimica et biophysica acta 2003;1625(2):173-82.
2002: Dae-Kee Kim; Namkyu Lee
Recent advances in topoisomerase I-targeting agents, camptothecin analogues.
Mini reviews in medicinal chemistry 2002;2(6):611-9.
2002: Seongeun Lee; Myungin Baek; Hankwang Yang; Yung-Jue Bang; Woo Ho Kim; Ji-Hong Ha; Dae-Kee Kim; Doo-Il Jeoung
Identification of genes differentially expressed between gastric cancers and normal gastric mucosa with cDNA microarrays.
Cancer letters 2002;184(2):197-206.
2001: Dae-Kee Kim; JY Lee; Namkyu Lee; DH Ryu; JS Kim; S Lee; JY Choi; JH Ryu; NH Kim; GJ Im; WS Choi; TK Kim
Synthesis and phosphodiesterase inhibitory activity of new sildenafil analogues containing a carboxylic acid group in the 5'-sulfonamide moiety of a phenyl ring.
Bioorganic & medicinal chemistry 2001;9(11):3013-21.
2001: Dae-Kee Kim; DH Ryu; Namkyu Lee; JY Lee; JS Kim; S Lee; JY Choi; JH Ryu; NH Kim; GJ Im; WS Choi; TK Kim
Synthesis and phosphodiesterase 5 inhibitory activity of new 5-phenyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one derivatives containing an N-acylamido group phenyl ring.
Bioorganic & medicinal chemistry 2001;9(7):1895-9.
2001: WS Choi; GJ Im; Dae-Kee Kim; TK Kim; I Jung; TS Kim; S J Lee; Namkyu Lee; YW Kim; JS Kim; K Chang
Pharmacokinetic studies of 2-amino-9-(3-acetoxymethyl-4-isopropoxycarbonyl-oxybut-1-yl)purine, an oral prodrug for the antiviral agent penciclovir.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(7):945-9.
2001: Dae-Kee Kim; Namkyu Lee; JY Lee; DH Ryu; JS Kim; S H Lee; JY Choi; K Chang; YW Kim; GJ Im; WS Choi; TK Kim; JH Ryu; NH Kim; K Lee
Synthesis and phosphodiesterase 5 inhibitory activity of novel phenyl ring modified sildenafil analogues.
Bioorganic & medicinal chemistry 2001;9(6):1609-16.
2001: Dae-Kee Kim; DH Ryu; JY Lee; Namkyu Lee; YW Kim; JS Kim; K Chang; GJ Im; TK Kim; WS Choi
Synthesis and biological evaluation of novel A-ring modified hexacyclic camptothecin analogues.
Journal of medicinal chemistry 2001;44(10):1594-602.
2000: Keun-Ho Ryu; Hae-In Rhee; I Jung; TS Kim; S J Lee; GJ Im; Namkyu Lee; DH Ryu; YW Kim; J J Kim; K Chang; Byung Ho Lee; H S Shin; E J Kim; KH Kim; Dae-Kee Kim
General pharmacology of the new antiviral agent SK 1899.
Arzneimittel-Forschung 2000;50(4):395-403.
1999: Dae-Kee Kim; Namkyu Lee; DH Ryu; YW Kim; JS Kim; K Chang; GJ Im; WS Choi; Y B Cho; KH Kim; Danni Colledge; Stephen Locarnini
Synthesis and evaluation of 2-amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines and 2-amino-9-(3-alkoxycarbonyloxymethyl-4-alkoxycarbonyloxybut-1- yl)purines as potential prodrugs of penciclovir.
Bioorganic & medicinal chemistry 1999;7(8):1715-25.
1999: Dae-Kee Kim; Namkyu Lee; H T Kim; GJ Im; KH Kim
Synthesis and evaluation of 2-amino-6-fluoro-9-(4-hydroxy-3-hydroxymethylbut-1-yl)purine mono- and diesters as potential prodrugs of penciclovir.
Bioorganic & medicinal chemistry 1999;7(3):565-70.
1999: Dae-Kee Kim; Namkyu Lee; YW Kim; K Chang; GJ Im; WS Choi; KH Kim
Synthesis and evaluation of amino acid esters of 6-deoxypenciclovir as potential prodrugs of penciclovir.
Bioorganic & medicinal chemistry 1999;7(2):419-24.
1999: Dae-Kee Kim; K Chang; GJ Im; H T Kim; Namkyu Lee; KH Kim
Synthesis and evaluation of 2-amino-9-(1, 3-dihydroxy-2-propoxymethyl)- 6-fluoropurine mono- and diesters as potential prodrugs of ganciclovir.
Journal of medicinal chemistry 1999;42(2):324-8.
1998: Dae-Kee Kim; Namkyu Lee; GJ Im; H T Kim; KH Kim
Synthesis and evaluation of 2-amino-6-fluoro-9-(2-hydroxyethoxymethyl)purine esters as potential prodrugs of acyclovir.
Bioorganic & medicinal chemistry 1998;6(12):2525-30.
1998: Dae-Kee Kim; Namkyu Lee; YW Kim; K Chang; JS Kim; GJ Im; WS Choi; I Jung; TS Kim; Y Y Hwang; D S Min; K A Um; Y B Cho; KH Kim
Synthesis and evaluation of 2-amino-9-(3-hydroxymethyl-4-alkoxycarbonyloxybut-1-yl)purines as potential prodrugs of penciclovir.
Journal of medicinal chemistry 1998;41(18):3435-41.
1997: Dae-Kee Kim; J Gam; Y W Kim; J Lim; H T Kim; KH Kim
Synthesis and anti-HIV-1 activity of a series of 1-alkoxy-5-alkyl-6-(arylthio)uracils.
Journal of medicinal chemistry 1997;40(15):2363-73.
1996: Y B Cho; KH Kim; Dae-Kee Kim; G Miyamoto
Mammary excretion and placental transfer of cis-malonato[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane] platinum(II) in rats.
Arzneimittel-Forschung 1996;46(9):926-30.
1996: Y B Cho; Dae-Kee Kim; KH Kim; G Miyamoto
Pharmacokinetics of cis-malonato[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1, 3-dioxolane]platinum(II) in rats.
Arzneimittel-Forschung 1996;46(6):629-34.
1996: Dae-Kee Kim; Y B Cho; Haesook T Kim; T S Kim; KH Kim; Weon-Seon Hong
Pharmacokinetics of a new platinum compound, cis-(glycolato-O,O) [(4R,5R)-4,5-bis(aminomethyl)-1,3-dioxolane-2-spiro-1'-cyclohexane]plat inum (II) in dogs.
Anticancer research 1996;16(3A):1167-9.
1996: Dae-Kee Kim; Haesook T Kim; Y B Cho; T S Kim; KH Kim; Weon-Seon Hong
In vitro cytotoxicity, pharmacokinetics and ex vivo pharmacodynamics of a new platinum compound, cis-malonato [(4R,5R-4,5-bis(aminomethyl)-1,3-dioxolane-2-spiro-1'-cyclopentane] platinum (II).
Anticancer research 1996;16(1):251-6.
1995: H T Kim; Dae-Kee Kim; Y W Kim; KH Kim; Y Sugiyama; M Kikuchi
Antiviral activity of 9-[[(ethoxyhydroxyphosphinyl)-methoxy]methoxy] guanine against cytomegalovirus and herpes simplex virus.
Antiviral research 1995;28(3):243-51.
1995: Y B Cho; KH Kim; Dae-Kee Kim
Pharmacokinetics, tissue distribution, and excretion of cis-malonato[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3- dioxolane]platinum(II) in dogs.
Drug metabolism and disposition: the biological fate of chemicals 1995;23(11):1280-5.
1995: Weon-Seon Hong; Young Il Min; Haesook T Kim; Y B Cho; KH Kim; Dae-Kee Kim
Antitumor activity of five new platinum complexes having a glycolate leaving ligand.
Journal of Korean medical science 1995;10(4):269-74.
1995: Dae-Kee Kim; Haesook T Kim; Y B Cho; J H Tai; J S Ahn; T S Kim; KH Kim; Weon-Seon Hong
Antitumor activity of cis-malonato[(4R,5R)-4,5-bis(aminomethyl)-2- isopropyl-1,3-dioxolane]platinum(II), a new platinum analogue, as an anticancer agent.
Cancer chemotherapy and pharmacology 1995;35(5):441-5.
1995: Weon-Seon Hong; Haesook T Kim; KH Kim; Dae-Kee Kim
In vitro antitumor activity of a new platinum complex, cis-malonato [(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane] platinum (II) (SKI 2053R), against human lung and stomach cancer cell lines.
Anticancer research 1995;15(1):51-4.
1995: Dae-Kee Kim; Haesook T Kim; J H Tai; Y B Cho; T S Kim; KH Kim; J G Park; Weon-Seon Hong
Pharmacokinetics and antitumor activity of a new platinum compound, cis-malonato[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1, 3- dioxolane]platinum(II), as determined by ex vivo pharmacodynamics.
Cancer chemotherapy and pharmacology 1995;37(1-2):1-6.
1994: Dae-Kee Kim; J S Ahn; G Ryu; KH Kim; C W Park; M S Kim; M H Chung; Sang-Goo Shin; Yoo-Hun Suh; Y S Kim
General pharmacology of cis-malonato[4R,5R)-4,5-bis-(aminomethyl)-2-isopropyl-1,3- dioxolane]platinum(II).
Arzneimittel-Forschung 1994;44(9):1080-8.
1994: Dae-Kee Kim; G Kim; J Gam; Y B Cho; Haesook T Kim; J H Tai; KH Kim; Weon-Seon Hong; J G Park
Synthesis and antitumor activity of a series of [2-substituted-4,5-bis(aminomethyl)-1,3-dioxolane]platinum(II) complexes.
Journal of medicinal chemistry 1994;37(10):1471-85.