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Gi-Young Kim

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Chang-Hee Kang; Yung Hyun Choi; Yong-Kee Jeong; Wol-Soon Jo; Min Jeong Kim; Kyung-Tae Lee; Min Jeong Seo; Gi-Young Kim
5-Hydroxy-3,6,7,8,3'4'-hexamethoxyflavone inhibits nitric oxide production in lipopolysaccharide-stimulated BV2 microglia via NF-κB suppression and Nrf-2-dependent heme oxygenase-1 induction.
Shin-Hyung Park; Young-Chae Chang; Gyoo Yong Chi; Jin Won Hyun; Gi-Young Kim; Wun-Jae Kim; Jun Hyuk Lee; Sung-Kwon Moon; Hyun Soo Park; Yung Hyun Choi
Induction of endoplasmic reticulum stress-mediated apoptosis and non-canonical autophagy by luteolin in NCI-H460 lung carcinoma cells.
Dong Yeok Shin; Ho Sung Kang; Young Hyun Yoo; Gi-Young Kim; Wun-Jae Kim; Yung Hyun Choi
Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells.

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2013: Chang-Hee Kang; Yung Hyun Choi; Yong-Kee Jeong; Wol-Soon Jo; Min Jeong Kim; Kyung-Tae Lee; Min Jeong Seo; Gi-Young Kim
5-Hydroxy-3,6,7,8,3'4'-hexamethoxyflavone inhibits nitric oxide production in lipopolysaccharide-stimulated BV2 microglia via NF-κB suppression and Nrf-2-dependent heme oxygenase-1 induction.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013;57():119-25.
2013: Shin-Hyung Park; Young-Chae Chang; Gyoo Yong Chi; Jin Won Hyun; Gi-Young Kim; Wun-Jae Kim; Jun Hyuk Lee; Sung-Kwon Moon; Hyun Soo Park; Yung Hyun Choi
Induction of endoplasmic reticulum stress-mediated apoptosis and non-canonical autophagy by luteolin in NCI-H460 lung carcinoma cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013;56():100-9.
2013: Dong Yeok Shin; Ho Sung Kang; Young Hyun Yoo; Gi-Young Kim; Wun-Jae Kim; Yung Hyun Choi
Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2013;67(4):305-11.
2013: R G P T Jayasooriya; Bo Yeon Kim; Mun-Ock Kim; Dong-Oh Moon; Sung Gyu Yun; Jong Seog Ahn; Yukihiro Asami; Yung Hyun Choi; Jae-Hyuk Jang; Gi-Young Kim
Verrucarin A enhances TRAIL-induced apoptosis via NF-κB-mediated Fas overexpression.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013;55():1-7.
2013: Matharage Gayani Dilshara; Young Pyo Jang; Rajapaksha Gendara Prasad Tharanga Jayasooriya; Joon Bum Jeong; Jin-Woo Jeong; Yong-Kee Jeong; Seungheon Lee; Yong Taek Seo; Yung Hyun Choi; Gi-Young Kim
Water extract of processed Hydrangea macrophylla (Thunb.) Ser. leaf attenuates the expression of pro-inflammatory mediators by suppressing Akt-mediated NF-κB activation.
Environmental toxicology and pharmacology 2013;35(2):311-9.
2013: Chang-Hee Kang; Yung Hyun Choi; Rajapaksha Gendara Prasad Tharanga Jayasooriya; Wun-Jae Kim; Sung-Kwon Moon; Gi-Young Kim
β-Ionone attenuates LPS-induced pro-inflammatory mediators such as NO, PGE2 and TNF-α in BV2 microglial cells via suppression of the NF-κB and MAPK pathway.
Toxicology in vitro : an international journal published in association with BIBRA 2013;27(2):782-7.
2013: Gi-Young Kim
Reply to the letter to the editor.
Toxicology in vitro : an international journal published in association with BIBRA 2013;27(2):992.
2013: Gi-Young Kim; Wun-Jae Kim; Yung Hyun Choi
Correction: kim, g.-Y. Et Al. Pectenotoxin-2 from marine sponges: a potential anti-cancer agent-a review. Mar. Drugs 2011, 9, 2176-2187.
Marine drugs 2013;11(5):1490-1.
2013: Jin-Woo Jeong; Gi-Young Kim; Won Sup Lee; Sung Chul Shin; Byung Tae Choi; Yung Hyun Choi
Anthocyanins Downregulate Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglial Cells by Suppressing the NF-κB and Akt/MAPKs Signaling Pathways.
International journal of molecular sciences 2013;14(1):1502-15.
2013: Su Hyun Hong; Gi-Young Kim; Wun-Jae Kim; Sung-Kwon Moon; Young-Chae Chang; Yung Hyun Choi
Bufalin prevents the migration and invasion of T24 bladder carcinoma cells through the inactivation of matrix metalloproteinases and modulation of tight junctions.
International journal of oncology 2013;42(1):277-86.
2012: Chang-Hee Kang; Nam Deuk Kim; Yung Hyun Choi; Matharage Gayani Dilshara; Rajapaksha Gendara Prasad Tharanga Jayasooriya; Yong-Kee Jeong; Gi-Young Kim
Caffeine suppresses lipopolysaccharide-stimulated BV2 microglial cells by suppressing Akt-mediated NF-κB activation and ERK phosphorylation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(12):4270-6.
2012: Dong Yeok Shin; Ho Sung Kang; Chan Gil Kim; Gi-Young Kim; Wun-Jae Kim; Yung Hyun Choi
Anti-invasive effects of decitabine, a DNA methyltransferase inhibitor, through tightening of tight junctions and inhibition of matrix metalloproteinase activities in AGS human gastric carcinoma cells.
Oncology reports 2012;28(3):1043-50.
2012: Shin-Hyung Park; Young Hyun Yoo; Young-Chae Chang; Gyoo Yong Chi; Gi-Young Kim; Jeong-Hwan Kim; Wun-Jae Kim; Sung-Kwon Moon; Soo-Wan Nam; Yung Hyun Choi
Induction of apoptosis and autophagy by sodium selenite in A549 human lung carcinoma cells through generation of reactive oxygen species.
Toxicology letters 2012;212(3):252-61.
2012: R G P T Jayasooriya; Chang-Hee Kang; Sang-Hyuck Kang; Weon-Young Chang; Yung Hyun Choi; Jin-Won Hyun; Dong-Oh Moon; Gi-Young Kim
Apigenin decreases cell viability and telomerase activity in human leukemia cell lines.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(8):2605-11.
2012: Hye Young Park; Hye Jin Hwang; Byung-Woo Kim; Gi-Young Kim; Nam Deuk Kim; Wun-Jae Kim; Yung Hyun Choi
Inhibitory effects of diallyl disulfide on the production of inflammatory mediators and cytokines in lipopolysaccharide-activated BV2 microglia.
Toxicology and applied pharmacology 2012;262(2):177-84.
2012: Hye Young Park; Gi-Young Kim; Yung Hyun Choi
Naringenin attenuates the release of pro-inflammatory mediators from lipopolysaccharide-stimulated BV2 microglia by inactivating nuclear factor-κB and inhibiting mitogen-activated protein kinases.
International journal of molecular medicine 2012;30(1):204-10.
2012: Hye Young Park; Young Hyun Yoo; Jin Won Hyun; Chan Gil Kim; Gi-Young Kim; Nam Deuk Kim; Wun-Jae Kim; Yung Hyun Choi
7,8-dihydroxyflavone induces G1 arrest of the cell cycle in U937 human monocytic leukemia cells via induction of the Cdk inhibitor p27 and downregulation of pRB phosphorylation.
Oncology reports 2012;28(1):353-7.
2012: Hye Young Park; Hye Jin Hwang; Jin Won Hyun; Byung-Woo Kim; Gi-Young Kim; Nam Deuk Kim; Yung Hyun Choi
7,8-Dihydroxyflavone exhibits anti-inflammatory properties by downregulating the NF-κB and MAPK signaling pathways in lipopolysaccharide-treated RAW264.7 cells.
International journal of molecular medicine 2012;29(6):1146-52.
2012: Shin-Hyung Park; Young Hyun Yoo; Gyoo Yong Chi; Hyun Sup Eom; Jin Won Hyun; Gi-Young Kim; Wun-Jae Kim; Su-Jae Lee; Yung Hyun Choi
Role of autophagy in apoptosis induction by methylene chloride extracts of Mori cortex in NCI-H460 human lung carcinoma cells.
International journal of oncology 2012;40(6):1929-40.
2012: Min Ho Han; Hye Jin Hwang; Jin Myung Jung; Gonsup Kim; Gi-Young Kim; Taeg Kyu Kwon; Won Sup Lee; Jing Nan Lu; Chung Ho Ryu; Yung Hyun Choi
Citrus aurantium L. exhibits apoptotic effects on U937 human leukemia cells partly through inhibition of Akt.
International journal of oncology 2012;40(6):2090-6.
2012: Mohammad Akbar Hossain; Jung Yoon Jang; Yong Jung Kang; Dong Hwan Kim; Gi-Young Kim; Yung Hyun Choi; Hae Young Chung; Bryan L Copple; Jeon-Ok Moon; Jeong-Hyun Yoon; Nam Deuk Kim
Aspirin enhances doxorubicin-induced apoptosis and reduces tumor growth in human hepatocellular carcinoma cells in vitro and in vivo.
International journal of oncology 2012;40(5):1636-42.
2012: Jin-Woo Jeong; Yong-Kee Jeong; Cheng-Yun Jin; Chan Gil Kim; Gi-Young Kim; Wun-Jae Kim; Jae-Dong Lee; Sung-Kwon Moon; Cheol Park; Min Ho Han; Yung Hyun Choi
Inhibition of migration and invasion of LNCaP human prostate carcinoma cells by cordycepin through inactivation of Akt.
International journal of oncology 2012;40(5):1697-704.
2012: Jung-Eun Koo; Young-Hee Maeng; Vivek Bhakta Mathema; Weon-Young Chang; Hye-Jin Hong; Chang-Lim Hyun; Jin-Won Hyun; Hee-Kyoung Kang; Gi-Young Kim; Young Ree Kim; Young-Sang Koh
Inhibitory effects of Carpinus tschonoskii leaves extract on CpG-stimulated pro-inflammatory cytokine production in murine bone marrow-derived macrophages and dendritic cells.
In vitro cellular & developmental biology. Animal 2012;48(4):197-202.
2012: Mohammad Akbar Hossain; Jung Yoon Jang; Yong Jung Kang; Dong Hwan Kim; Gi-Young Kim; Yung Hyun Choi; Hae Young Chung; Bryan L Copple; Jeon-Ok Moon; Jeong-Hyun Yoon; Nam Deuk Kim
Aspirin induces apoptosis in vitro and inhibits tumor growth of human hepatocellular carcinoma cells in a nude mouse xenograft model.
International journal of oncology 2012;40(4):1298-304.
2012: Rajapaksha Gedara Prasad Tharanga Jayasooriya; Wun-Jae Kim; Sung-Kwon Moon; Yung Hyun Choi; Gi-Young Kim
Methanol extract of Hydroclathrus clathratus suppresses matrix metalloproteinase-9 in T24 bladder carcinoma cells by suppressing the NF-κB and MAPK pathways.
Oncology reports 2012;27(2):541-6.
2012: Min Ho Han; Jin Myung Jung; Gonsup Kim; Gi-Young Kim; Wun-Jae Kim; Su-Jae Lee; Won Sup Lee; Jing Nan Lu; Jeong Won Yun; Yung Hyun Choi
Tetraarsenic Hexoxide Induces Beclin-1-Induced Autophagic Cell Death as well as Caspase-Dependent Apoptosis in U937 Human Leukemic Cells.
Evidence-based complementary and alternative medicine : eCAM 2012;2012():201414.
2011: Rajapaksha Gedara Prasad Tharanga Jayasooriya; Yong-Kee Jeong; Chang-Hee Kang; Yung Hyun Choi; Min-Jeong Seo; Gi-Young Kim
Exopolysaccharide of Laetiporus sulphureus var. miniatus downregulates LPS-induced production of NO, PGE₂, and TNF-α in BV2 microglia cells via suppression of the NF-κB pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011;49(11):2758-64.
2011: Cheol Park; Yong-Kee Jeong; Cheng-Yun Jin; Gi-Young Kim; Wun-Jae Kim; Yung Hyun Choi
Induction of apoptosis by ethanol extract of Prunus mume in U937 human leukemia cells through activation of caspases.
Oncology reports 2011;26(4):987-93.
2011: Dong-Oh Moon; Yung Hyun Choi; Gi-Young Kim
Role of p21 in SP600125-induced cell cycle arrest, endoreduplication, and apoptosis.
Cellular and molecular life sciences : CMLS 2011;68(19):3249-60.
2011: Hye Young Park; Il-Whan Choi; Min Ho Han; Cheng-Yun Jin; Gi-Young Kim; Nam Deuk Kim; Taeg Kyu Kwon; Taek-Jeong Nam; Cheol Park; Yung Hyun Choi
Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011;49(8):1745-52.
2011: Cheol Park; Gi-Young Kim; Jee Hyung Jung; Wun-Jae Kim; Yung Hyun Choi
Pectenotoxin-2 induces G1 arrest of the cell cycle in synovial fibroblasts of patients with rheumatoid arthritis.
International journal of molecular medicine 2011;27(6):783-7.
2011: Hyun Soo Park; Nam Deuk Kim; Gi-Young Kim; Taek-Jeong Nam; Yung Hyun Choi
Antiproliferative activity of fucoidan was associated with the induction of apoptosis and autophagy in AGS human gastric cancer cells.
Journal of food science 2011;76(3):T77-83.
2011: Dong-Oh Moon; Yung Hyun Choi; Sung-Kwon Moon; Wun-Jae Kim; Gi-Young Kim
Gossypol decreases tumor necrosis factor-α-induced intercellular adhesion molecule-1 expression via suppression of NF-κB activity.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011;49(4):999-1005.
2011: Chang-Hee Kang; Dong-Oh Moon; Yung Hyun Choi; Il-Whan Choi; Sung-Kwon Moon; Wun-Jae Kim; Gi-Young Kim
Piceatannol enhances TRAIL-induced apoptosis in human leukemia THP-1 cells through Sp1- and ERK-dependent DR5 up-regulation.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(3):605-12.
2011: Cheng-Yun Jin; Cheol Park; Hye Jin Hwang; Gi-Young Kim; Byung Tae Choi; Wun-Jae Kim; Yung Hyun Choi
Naringenin up-regulates the expression of death receptor 5 and enhances TRAIL-induced apoptosis in human lung cancer A549 cells.
Molecular nutrition & food research 2011;55(2):300-9.
2011: Mun-Ock Kim; Won Sup Lee; Dong-Oh Moon; Yung Hyun Choi; Jin Myung Jung; Gi-Young Kim
Agaricus blazei Extract Induces Apoptosis through ROS-Dependent JNK Activation Involving the Mitochondrial Pathway and Suppression of Constitutive NF-κB in THP-1 Cells.
Evidence-based complementary and alternative medicine : eCAM 2011;2011():838172.
2010: Jin-Woo Jeong; Cheng-Yun Jin; Gi-Young Kim; Jae-Dong Lee; Cheol Park; Gun-Do Kim; Wun-Jae Kim; Won-Kyo Jung; Su Kil Seo; Il-Whan Choi; Yung Hyun Choi
Anti-inflammatory effects of cordycepin via suppression of inflammatory mediators in BV2 microglial cells.
International immunopharmacology 2010;10(12):1580-6.
2010: Cheol Park; Cheng-Yun Jin; Gi-Young Kim; JaeHun Cheong; Jee H Jung; Young Hyun Yoo; Yung Hyun Choi
A methyl jasmonate derivative, J-7, induces apoptosis in human hepatocarcinoma Hep3B cells in vitro.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(7):1920-6.
2010: Dong-Oh Moon; Yung Hyun Choi; Sung-Kwon Moon; Wun-Jae Kim; Gi-Young Kim
Butein suppresses the expression of nuclear factor-kappa B-mediated matrix metalloproteinase-9 and vascular endothelial growth factor in prostate cancer cells.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(7):1927-34.
2010: Dong-Oh Moon; Sang-Hyuck Kang; Ki-Cheon Kim; Mun-Ock Kim; Yung Hyun Choi; Gi-Young Kim
Sulforaphane decreases viability and telomerase activity in hepatocellular carcinoma Hep3B cells through the reactive oxygen species-dependent pathway.
Cancer letters 2010;295(2):260-6.
2010: Dong Yeok Shin; Gi-Young Kim; Jung-In Kim; Moo Kyoung Yoon; Taeg Kyu Kwon; Su-Jae Lee; Young-Whan Choi; Ho Sung Kang; Young Hyun Yoo; Yung Hyun Choi
Anti-invasive activity of diallyl disulfide through tightening of tight junctions and inhibition of matrix metalloproteinase activities in LNCaP prostate cancer cells.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(6):1569-76.
2010: Dong-Oh Moon; Mun-Ock Kim; Taek-Jeong Nam; Se-Kwon Kim; Yung Hyun Choi; Gi-Young Kim
Pectenotoxin-2 induces G2/M phase cell cycle arrest in human breast cancer cells via ATM and Chk1/2-mediated phosphorylation of cdc25C.
Oncology reports 2010;24(1):271-6.
2010: Dong-Oh Moon; Mun-Ock Kim; Yung Hyun Choi; Gi-Young Kim
Butein sensitizes human hepatoma cells to TRAIL-induced apoptosis via extracellular signal-regulated kinase/Sp1-dependent DR5 upregulation and NF-kappaB inactivation.
Molecular cancer therapeutics 2010;9(6):1583-95.
2010: Dong-Oh Moon; Mun-Ock Kim; Sang-Hyuck Kang; Yung Hyun Choi; Sung Yong Park; Gi-Young Kim
HA14-1 sensitizes TNF-alpha-induced apoptosis via inhibition of the NF-kappaB signaling pathway: involvement of reactive oxygen species and JNK.
Cancer letters 2010;292(1):111-8.
2010: Dong-Oh Moon; Mun-Ok Kim; Yung Hyun Choi; Yung-Min Park; Gi-Young Kim
Curcumin attenuates inflammatory response in IL-1beta-induced human synovial fibroblasts and collagen-induced arthritis in mouse model.
International immunopharmacology 2010;10(5):605-10.
2010: Mun-Ock Kim; Dong-Oh Moon; Chang-Hee Kang; Taeg Kyu Kwon; Yung Hyun Choi; Gi-Young Kim
beta-Ionone enhances TRAIL-induced apoptosis in hepatocellular carcinoma cells through Sp1-dependent upregulation of DR5 and downregulation of NF-kappaB activity.
Molecular cancer therapeutics 2010;9(4):833-43.
2010: Jong-Hwan Kim; Young-Whan Choi; Cheol Park; Cheng-Yun Jin; You Jin Lee; Da Jung Park; Sun Guen Kim; Gi-Young Kim; Il-Whan Choi; Won-Deuk Hwang; Yong Kee Jeong; Se-Kwon Kim; Yung Hyun Choi
Apoptosis induction of human leukemia U937 cells by gomisin N, a dibenzocyclooctadiene lignan, isolated from Schizandra chinensis Baill.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2010;48(3):807-13.
2010: Cheol Park; Cheng-Yun Jin; Hyun Ju Kwon; Hye Jin Hwang; Gi-Young Kim; Il-Whan Choi; Taeg Kyu Kwon; Byung-Woo Kim; Wun-Jae Kim; Yung Hyun Choi
Induction of apoptosis by esculetin in human leukemia U937 cells: roles of Bcl-2 and extracellular-regulated kinase signaling.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(2):486-94.
2010: Dong-Oh Moon; Mun-Ock Kim; Yung Hyun Choi; Jin Won Hyun; Weon Young Chang; Gi-Young Kim
Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation.
Cancer letters 2010;288(2):204-13.
2010: Dong-Oh Moon; Mun-Ock Kim; Jae-Dong Lee; Yung Hyun Choi; Gi-Young Kim
Rosmarinic acid sensitizes cell death through suppression of TNF-alpha-induced NF-kappaB activation and ROS generation in human leukemia U937 cells.
Cancer letters 2010;288(2):183-91.
2009: Dong-Oh Moon; Mun-Ock Kim; Jae-Dong Lee; Yung Hyun Choi; Gi-Young Kim
Butein suppresses c-Myc-dependent transcription and Akt-dependent phosphorylation of hTERT in human leukemia cells.
Cancer letters 2009;286(2):172-9.
2009: Woo Young Choi; Cheng-Yun Jin; Min Ho Han; Gi-Young Kim; Nam Deuk Kim; Won Ho Lee; Se-Kwon Kim; Yung Hyun Choi
Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis via down-regulation of AKT and activation of caspase-3.
Anticancer research 2009;29(11):4457-65.
2009: Dong-Oh Moon; Mun-Ock Kim; Moon-Soo Heo; Jae-Dong Lee; Yung Hyun Choi; Gi-Young Kim
Gefitinib induces apoptosis and decreases telomerase activity in MDA-MB-231 human breast cancer cells.
Archives of pharmacal research 2009;32(10):1351-60.
2009: Mahanama De Zoysa; Chamilani Nikapitiya; Dong-Oh Moon; Ilson Whang; Gi-Young Kim; Jehee Lee
A novel Fas ligand in mollusk abalone: molecular characterization, immune responses and biological activity of the recombinant protein.
Fish & shellfish immunology 2009;27(3):423-32.
2009: Yung Hyun Choi; Woo Young Choi; Su Hyun Hong; Sung Ok Kim; Gi-Young Kim; Won Ho Lee; Young Hyun Yoo
Anti-invasive activity of sanguinarine through modulation of tight junctions and matrix metalloproteinase activities in MDA-MB-231 human breast carcinoma cells.
Chemico-biological interactions 2009;179(2-3):185-91.
2009: Dong-Oh Moon; Mun-Ock Kim; Sang-Hyuck Kang; Yung Hyun Choi; Gi-Young Kim
Sulforaphane suppresses TNF-alpha-mediated activation of NF-kappaB and induces apoptosis through activation of reactive oxygen species-dependent caspase-3.
Cancer letters 2009;274(1):132-42.
2009: Sang Eun Park; Cheol Park; Sun Hee Kim; Mohammad Akbar Hossain; Min Young Kim; Hae Young Chung; Woo Sung Son; Gi-Young Kim; Yung Hyun Choi; Nam Deuk Kim
Korean red ginseng extract induces apoptosis and decreases telomerase activity in human leukemia cells.
Journal of ethnopharmacology 2009;121(2):304-12.
2008: Mun-Ock Kim; Dong-Oh Moon; Moon-Soo Heo; Jae-Dong Lee; Jee Hyung Jung; Se-Kwon Kim; Yung Hyun Choi; Gi-Young Kim
Pectenotoxin-2 abolishes constitutively activated NF-kappaB, leading to suppression of NF-kappaB related gene products and potentiation of apoptosis.
Cancer letters 2008;271(1):25-33.
2008: Dong Yeok Shin; Hee Jae Shin; Gi-Young Kim; JaeHun Cheong; Il-Whan Choi; Se-Kwon Kim; Sung-Kwon Moon; Ho Sung Kang; Yung Hyun Choi
Streptochlorin isolated from Streptomyces sp. Induces apoptosis in human hepatocarcinoma cells through a reactive oxygen species-mediated mitochondrial pathway.
Journal of microbiology and biotechnology 2008;18(11):1862-8.
2008: Sang Eun Park; Sun Wha Lee; Mohammad Akbar Hossain; Min Young Kim; Mi-Na Kim; Eun Young Ahn; Young Chul Park; Hongsuk Suh; Gi-Young Kim; Yung Hyun Choi; Nam Deuk Kim
A chenodeoxycholic derivative, HS-1200, induces apoptosis and cell cycle modulation via Egr-1 gene expression control on human hepatoma cells.
Cancer letters 2008;270(1):77-86.
2008: Dong-Oh Moon; Mun-Ock Kim; Hee-Jeong Lee; Yung Hyun Choi; Yeong-Min Park; Moon-Soo Heo; Gi-Young Kim
Curcumin attenuates ovalbumin-induced airway inflammation by regulating nitric oxide.
Biochemical and biophysical research communications 2008;375(2):275-9.
2008: Dong-Oh Moon; Mun-Ock Kim; Yung Hyun Choi; Hee Gu Lee; Nam Deuk Kim; Gi-Young Kim
Gossypol suppresses telomerase activity in human leukemia cells via regulating hTERT.
FEBS letters 2008;582(23-24):3367-73.
2008: Mun-Ock Kim; Dong-Oh Moon; Sang-Hyuck Kang; Moon-Soo Heo; Yung Hyun Choi; Jee Hyung Jung; Jae-Dong Lee; Gi-Young Kim
Pectenotoxin-2 represses telomerase activity in human leukemia cells through suppression of hTERT gene expression and Akt-dependent hTERT phosphorylation.
FEBS letters 2008;582(23-24):3263-9.
2008: Chang-Min Lee; Jeong-Hyun Chang; Dong-Oh Moon; Yung Hyun Choi; Il-Whan Choi; Yeong-Min Park; Gi-Young Kim
Lycopene suppresses ovalbumin-induced airway inflammation in a murine model of asthma.
Biochemical and biophysical research communications 2008;374(2):248-52.
2008: Cheol Park; Hee Jae Shin; Gi-Young Kim; Taeg Kyu Kwon; Taek-Jeong Nam; Se-Kwon Kim; JaeHun Cheong; Il-Whan Choi; Yung Hyun Choi
Induction of apoptosis by streptochlorin isolated from Streptomyces sp. in human leukemic U937 cells.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(6):1573-81.
2008: Dong-Oh Moon; Mun-Ock Kim; Sang-Hyuck Kang; Kyeong-Jun Lee; Moon-Soo Heo; Kwang-Sik Choi; Yung Hyun Choi; Gi-Young Kim
Induction of G2/M arrest, endoreduplication, and apoptosis by actin depolymerization agent pextenotoxin-2 in human leukemia cells, involving activation of ERK and JNK.
Biochemical pharmacology 2008;76(3):312-21.
2008: Dong-Oh Moon; Mun-Ock Kim; Yung Hyun Choi; Nam Deuk Kim; Jeong-Hyun Chang; Gi-Young Kim
Bcl-2 overexpression attenuates SP600125-induced apoptosis in human leukemia U937 cells.
Cancer letters 2008;264(2):316-25.
2008: Dong-Oh Moon; Mun-Ock Kim; Jae-Dong Lee; Gi-Young Kim
Gossypol suppresses NF-kappaB activity and NF-kappaB-related gene expression in human leukemia U937 cells.
Cancer letters 2008;264(2):192-200.
2008: Dong-Oh Moon; Mun-Ock Kim; Yung Hyun Choi; Gi-Young Kim
beta-Sitosterol induces G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways.
Cancer letters 2008;264(2):181-91.
2008: Mun-Ock Kim; Dong-Oh Moon; Yung Hyun Choi; Jae-Dong Lee; Nam Deuk Kim; Gi-Young Kim
Platycodin D induces mitotic arrest in vitro, leading to endoreduplication, inhibition of proliferation and apoptosis in leukemia cells.
International journal of cancer. Journal international du cancer 2008;122(12):2674-81.
2008: Mun-Ock Kim; Dong-Oh Moon; Yung Hyun Choi; Dong Yeok Shin; Ho Sung Kang; Byung Tae Choi; Jae-Dong Lee; Wei Li; Gi-Young Kim
Platycodin D induces apoptosis and decreases telomerase activity in human leukemia cells.
Cancer letters 2008;261(1):98-107.
2008: Jae Im Kwon; Gi-Young Kim; Kun-Young Park; Chung Ho Ryu; Yung Hyun Choi
Induction of apoptosis by linoleic acid is associated with the modulation of Bcl-2 family and Fas/FasL system and activation of caspases in AGS human gastric adenocarcinoma cells.
Journal of medicinal food 2008;11(1):1-8.
2008: Cheol Park; Dong-Oh Moon; Chung-Ho Ryu; Byung tae Choi; Won ho Lee; Gi-Young Kim; Yung hyun Choi
Beta-sitosterol sensitizes MDA-MB-231 cells to TRAIL-induced apoptosis.
Acta pharmacologica Sinica 2008;29(3):341-8.
2008: Cheol Park; Cheng-Yun Jin; Gi-Young Kim; Il-Whan Choi; Taeg Kyu Kwon; Byung Tae Choi; Su-Jae Lee; Won Ho Lee; Yung Hyun Choi
Induction of apoptosis by esculetin in human leukemia U937 cells through activation of JNK and ERK.
Toxicology and applied pharmacology 2008;227(2):219-28.
2008: Dong-Oh Moon; Sung-Yong Park; Yung Hyun Choi; Nam Deuk Kim; Chan Lee; Gi-Young Kim
Melittin induces Bcl-2 and caspase-3-dependent apoptosis through downregulation of Akt phosphorylation in human leukemic U937 cells.
Toxicon : official journal of the International Society on Toxinology 2008;51(1):112-20.
2007: Cheng-Yun Jin; Cheol Park; JaeHun Cheong; Byung Tae Choi; Tae Ho Lee; Jae-Dong Lee; Won Ho Lee; Gi-Young Kim; Chung Ho Ryu; Yung Hyun Choi
Genistein sensitizes TRAIL-resistant human gastric adenocarcinoma AGS cells through activation of caspase-3.
Cancer letters 2007;257(1):56-64.
2007: Cheng-Yun Jin; Jae-Dong Lee; Cheol Park; Yung Hyun Choi; Gi-Young Kim
Curcumin attenuates the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated BV2 microglia.
Acta pharmacologica Sinica 2007;28(10):1645-51.
2007: Cheol Park; Dong-Oh Moon; Il-Whan Choi; Byung Tae Choi; Taek-Jeong Nam; Chung-Ho Rhu; Taeg Kyu Kwon; Won Ho Lee; Gi-Young Kim; Yung Hyun Choi
Curcumin induces apoptosis and inhibits prostaglandin E(2) production in synovial fibroblasts of patients with rheumatoid arthritis.
International journal of molecular medicine 2007;20(3):365-72.
2007: Cheng-Yun Jin; Dong-Oh Moon; Yung Hyun Choi; Jae-Dong Lee; Gi-Young Kim
Bcl-2 and caspase-3 are major regulators in Agaricus blazei-induced human leukemic U937 cell apoptosis through dephoshorylation of Akt.
Biological & pharmaceutical bulletin 2007;30(8):1432-7.
2007: Dong-Oh Moon; Moon-ok Kim; Jae-dong Lee; Yung Hyun Choi; Min-ki Lee; Gi-Young Kim
Molecular mechanisms of ZD1839 (Iressa)-induced apoptosis in human leukemic U937 cells.
Acta pharmacologica Sinica 2007;28(8):1205-14.
2007: Dong-Oh Moon; Sung-Yong Park; Kyeong-Jun Lee; Moon-Soo Heo; Ki-Cheon Kim; Mun-Ock Kim; Jae-Dong Lee; Yung Hyun Choi; Gi-Young Kim
Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia.
International immunopharmacology 2007;7(8):1092-101.
2007: Dong-Oh Moon; Kyeong-Jun Lee; Yung Hyun Choi; Gi-Young Kim
Beta-sitosterol-induced-apoptosis is mediated by the activation of ERK and the downregulation of Akt in MCA-102 murine fibrosarcoma cells.
International immunopharmacology 2007;7(8):1044-53.
2007: Cheol Park; Dong-Oh Moon; Chung-Ho Rhu; Byung Tae Choi; Won Ho Lee; Gi-Young Kim; Yung Hyun Choi
Beta-sitosterol induces anti-proliferation and apoptosis in human leukemic U937 cells through activation of caspase-3 and induction of Bax/Bcl-2 ratio.
Biological & pharmaceutical bulletin 2007;30(7):1317-23.
2007: Soung Young Park; Gi-Young Kim; Song-Ja Bae; Young Hyun Yoo; Yung Hyun Choi
Induction of apoptosis by isothiocyanate sulforaphane in human cervical carcinoma HeLa and hepatocarcinoma HepG2 cells through activation of caspase-3.
Oncology reports 2007;18(1):181-7.
2007: Young-Ae Kim; Gi-Young Kim; Kun-Young Park; Yung Hyun Choi
Resveratrol inhibits nitric oxide and prostaglandin E2 production by lipopolysaccharide-activated C6 microglia.
Journal of medicinal food 2007;10(2):218-24.
2007: Cheng-Yun Jin; Dong-Oh Moon; Jae-Dong Lee; Moon-Soo Heo; Yung Hyun Choi; Chang-Min Lee; Yeong-Min Park; Gi-Young Kim
Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma A549 cells.
Carcinogenesis 2007;28(5):1058-66.
2007: Dong-Oh Moon; Yung Hyun Choi; Nam-Duk Kim; Yeong-Min Park; Gi-Young Kim
Anti-inflammatory effects of beta-lapachone in lipopolysaccharide-stimulated BV2 microglia.
International immunopharmacology 2007;7(4):506-14.
2007: Dong-Oh Moon; Ki-Cheon Kim; Cheng-Yun Jin; Min-Ho Han; Cheol Park; Kyeong-Jun Lee; Yeong-Min Park; Yung Hyun Choi; Gi-Young Kim
Inhibitory effects of eicosapentaenoic acid on lipopolysaccharide-induced activation in BV2 microglia.
International immunopharmacology 2007;7(2):222-9.
2007: Jun Sik Lee; Sang Gap Kim; Hyung Keun Kim; TAE HYUNG LEE; Young-Il Jeong; Chang-Min Lee; Man-Soo Yoon; Yong Jin Na; Dong-Soo Suh; Nam Cheol Park; In-Hak Choi; Gi-Young Kim; Yung Hyun Choi; Hae Young Chung; Yeong-Min Park
Silibinin polarizes Th1/Th2 immune responses through the inhibition of immunostimulatory function of dendritic cells.
Journal of cellular physiology 2007;210(2):385-97.
2007: Cheol Park; Gi-Young Kim; Won Il Kim; Sang Hoon Hong; Dong Il Park; Nam Deuk Kim; Song-Ja Bae; Jee H Jung; Yung Hyun Choi
Induction of apoptosis by (Z)-stellettic acid C, an acetylenic acid from the sponge Stelletta sp., is associated with inhibition of telomerase activity in human leukemic U937 cells.
Chemotherapy 2007;53(3):160-8.
2007: Gi-Young Kim; Ho-Jin Chae; Ki-Hyung Kim; Man-Soo Yoon; Kyu-Sub Lee; Chang-Min Lee; Dong-Oh Moon; Jun-Sik Lee; Young-Il Jeong; Yung Hyun Choi; Yeong-Min Park
Dendritic cell-tumor fusion vaccine prevents tumor growth in vivo.
Bioscience, biotechnology, and biochemistry 2007;71(1):215-21.
2007: Dong-Oh Moon; Cheol Park; Moon-Soo Heo; Yeong-Min Park; Yung Hyun Choi; Gi-Young Kim
PD98059 triggers G1 arrest and apoptosis in human leukemic U937 cells through downregulation of Akt signal pathway.
International immunopharmacology 2007;7(1):36-45.
2006: Dong-Oh Moon; Sung-Yong Park; Moon-Soo Heo; Ki-Cheon Kim; Cheol Park; Woo Shin Ko; Yung Hyun Choi; Gi-Young Kim
Key regulators in bee venom-induced apoptosis are Bcl-2 and caspase-3 in human leukemic U937 cells through downregulation of ERK and Akt.
International immunopharmacology 2006;6(12):1796-807.
2006: Cheng-Yun Jin; Yung Hyun Choi; Dong-Oh Moon; Cheol Park; Yeong-Min Park; Sang-Cheol Jeong; Moon-Soo Heo; Tae-Ho Lee; Jae-Dong Lee; Gi-Young Kim
Induction of G2/M arrest and apoptosis in human gastric epithelial AGS cells by aqueous extract of Agaricus blazei.
Oncology reports 2006;16(6):1349-55.
2006: Cheng-Yun Jin; Dong-Oh Moon; Kyeong-Jun Lee; Mun-Ok Kim; Jae-Dong Lee; Yung Hyun Choi; Yeong-Min Park; Gi-Young Kim
Piceatannol attenuates lipopolysaccharide-induced NF-kappaB activation and NF-kappaB-related proinflammatory mediators in BV2 microglia.
Pharmacological research : the official journal of the Italian Pharmacological Society 2006;54(6):461-7.
2006: Sun Ae Lyu; Seung Yeon Lee; Song Jin Lee; Sung Woo Son; Mun Ok Kim; Gi-Young Kim; Young Hee Kim; Hwa Jung Yoon; Hoon Kim; Dong Il Park; Woo Shin Ko
Seungma-galgeun-tang attenuates proinflammatory activities through the inhibition of NF-kappaB signal pathway in the BV-2 microglial cells.
Journal of ethnopharmacology 2006;107(1):59-66.
2006: Dong-Oh Moon; Cheng-Yun Jin; Jae-Dong Lee; Yung Hyun Choi; Soon-Cheol Ahn; Chang-Min Lee; Sang-Cheol Jeong; Yeong-Min Park; Gi-Young Kim
Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: suppression of p38, JNK and NF-kappaB p65 as potential targets.
Biological & pharmaceutical bulletin 2006;29(7):1470-5.
2006: Cheol Park; Gi-Young Kim; Gun-Do Kim; Won Ho Lee; Jae Hun Cheong; Nam Deuk Kim; Song-Ja Bae; Jee H Jung; Yung Hyun Choi
Suppression of U937 human monocytic leukemia cell growth by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., via induction of Cdk inhibitor p16 and down-regulation of pRB phosphorylation.
Oncology reports 2006;16(1):171-6.
2006: Gi-Young Kim; Jae-Yoon Lee; Jeong-Ok Lee; Chung-Ho Ryu; Byung Tae Choi; Yong-Kee Jeong; Ki-Wan Lee; Sang-Chul Jeong; Yung Hyun Choi
Partial characterization and immunostimulatory effect of a novel polysaccharide-protein complex extracted from Phellinus linteus.
Bioscience, biotechnology, and biochemistry 2006;70(5):1218-26.
2006: Cheol Park; Gi-Young Kim; Gun-Do Kim; Byung Tae Choi; Yeong-Min Park; Yung Hyun Choi
Induction of G2/M arrest and inhibition of cyclooxygenase-2 activity by curcumin in human bladder cancer T24 cells.
Oncology reports 2006;15(5):1225-31.
2006: Gi-Young Kim; Woo Shin Ko; Jae-Yoon Lee; Jeong-Ok Lee; Chung-Ho Ryu; Byung Tae Choi; Yeong-Min Park; Yong-Kee Jeong; Kyeong-Jun Lee; Kwang-Sik Choi; Moon-Soo Heo; Yung Hyun Choi
Water extract of Cordyceps militaris enhances maturation of murine bone marrow-derived dendritic cells in vitro.
Biological & pharmaceutical bulletin 2006;29(2):354-60.
2006: Hyun Joo Woo; Kun-Young Park; Chung-Ho Rhu; Won Ho Lee; Byung Tae Choi; Gi-Young Kim; Yeong-Min Park; Yung Hyun Choi
Beta-lapachone, a quinone isolated from Tabebuia avellanedae, induces apoptosis in HepG2 hepatoma cell line through induction of Bax and activation of caspase.
Journal of medicinal food 2006;9(2):161-8.
2005: Sung-Chil Woo; Gi-Young Kim; Chang-Min Lee; Dong-Oh Moon; Hyung-Keun Kim; TAE HYUNG LEE; Yu-Seok Moon; Nam Cheol Park; Man-Soo Yoon; Kyu-Sub Lee; Yeong-Min Park
The maturation of murine bone marrow-derived dendritic cells by tumor lysate uptake in vitro is not essential for cancer immunotherapy.
Cancer biology & therapy 2005;4(12):1331-5.
2005: Gi-Young Kim; Moo-Yeol Lee; Hee-Jeong Lee; Dong-Oh Moon; Chang-Min Lee; Cheng-Yun Jin; Yung Hyun Choi; Yong-Kee Jeong; Kyung Tae Chung; Jae-Yun Lee; In-Hak Choi; Yeong-Min Park
Effect of water-soluble proteoglycan isolated from Agaricus blazei on the maturation of murine bone marrow-derived dendritic cells.
International immunopharmacology 2005;5(10):1523-32.
2005: Dong-Oh Moon; Se-Rim Choi; Chang-Min Lee; Gi-Young Kim; Hee-Jeong Lee; Yeong-Min Park
Epigallocatechin-3-gallate suppresses galactose-alpha1,4-galactose-1beta,4-glucose ceramide expression in TNF-alpha stimulated human intestinal epithelial cells through inhibition of MAPKs and NF-kappaB.
Journal of Korean medical science 2005;20(4):548-54.
2005: Gi-Young Kim; Ki-Hyung Kim; Soong-Hwan Lee; Man-Soo Yoon; Hee-Jeong Lee; Dong-Oh Moon; Chang-Min Lee; Soon-Cheol Ahn; Young Chul Park; Yeong-Min Park
Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-kappa B as potential targets.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):8116-24.
2005: Cheol Park; Sang Hoon Hong; Jae-Yun Lee; Gi-Young Kim; Byung Tae Choi; Yong Tea Lee; Dong Il Park; Yeong-Min Park; Yong-Kee Jeong; Yung Hyun Choi
Growth inhibition of U937 leukemia cells by aqueous extract of Cordyceps militaris through induction of apoptosis.
Oncology reports 2005;13(6):1211-6.
2004: Gi-Young Kim; Gap-Seong Choi; Sang-Hee Lee; Yeong-Min Park
Acidic polysaccharide isolated from Phellinus linteus enhances through the up-regulation of nitric oxide and tumor necrosis factor-alpha from peritoneal macrophages.
Journal of ethnopharmacology 2004;95(1):69-76.
2004: Gi-Young Kim; Won-Kyo Oh; Byung-Cheul Shin; Yong-Il Shin; Young Chul Park; Soon-Cheol Ahn; Jae-Dong Lee; Yoe-Sik Bae; Jong-Young Kwak; Yeong-Min Park
Proteoglycan isolated from Phellinus linteus inhibits tumor growth through mechanisms leading to an activation of CD11c+CD8+ DC and type I helper T cell-dominant immune state.
FEBS letters 2004;576(3):391-400.
2004: Gi-Young Kim; Myung-Geum Han; Yung-Sun Song; Byung-Cheul Shin; Yong-Il Shin; Hee-Jeong Lee; Dong-Oh Moon; Chang-Min Lee; Jong-Young Kwak; Yoe-Sik Bae; Jae-Dong Lee; Yeong-Min Park
Proteoglycan isolated from Phellinus linteus induces toll-like receptors 2- and 4-mediated maturation of murine dendritic cells via activation of ERK, p38, and NF-kappaB.
Biological & pharmaceutical bulletin 2004;27(10):1656-62.
2004: Gi-Young Kim; Jong-Hyun Kim; Soon-Cheol Ahn; Hee-Jeong Lee; Dong-Oh Moon; Chang-Min Lee; Yeong-Min Park
Lycopene suppresses the lipopolysaccharide-induced phenotypic and functional maturation of murine dendritic cells through inhibition of mitogen-activated protein kinases and nuclear factor-kappaB.
Immunology 2004;113(2):203-11.
2004: Gi-Young Kim; Hoon Cho; Soon-Cheol Ahn; Yang-Hyo Oh; Chang-Min Lee; Yeong-Min Park
Resveratrol inhibits phenotypic and functional maturation of murine bone marrow-derived dendritic cells.
International immunopharmacology 2004;4(2):245-53.
2004: Soon-Cheol Ahn; Gi-Young Kim; Jin-Hyung Kim; Seong-Wan Baik; Myung-Kwan Han; Hee-Jeong Lee; Dong-Oh Moon; Chang-Min Lee; Ju-Hyung Kang; Bo-Hye Kim; Yang-Hyo Oh; Yeong-Min Park
Epigallocatechin-3-gallate, constituent of green tea, suppresses the LPS-induced phenotypic and functional maturation of murine dendritic cells through inhibition of mitogen-activated protein kinases and NF-kappaB.
Biochemical and biophysical research communications 2004;313(1):148-55.
2003: Soon-Kew Park; Gi-Young Kim; Jae-Young Lim; Jong-Young Kwak; Yoe-Sik Bae; Jae-Dong Lee; Yang-Hyo Oh; Soon-Cheol Ahn; Yeong-Min Park
Acidic polysaccharides isolated from Phellinus linteus induce phenotypic and functional maturation of murine dendritic cells.
Biochemical and biophysical research communications 2003;312(2):449-58.
2003: Gi-Young Kim; Su-In Roh; Soon-Kew Park; Soon-Cheol Ahn; Yang-Hyo Oh; Jae-Dong Lee; Yeong-Min Park
Alleviation of experimental septic shock in mice by acidic polysaccharide isolated from the medicinal mushroom Phellinus linteus.
Biological & pharmaceutical bulletin 2003;26(10):1418-23.
2003: Gi-Young Kim; Yang-Hyo Oh; Yeong-Min Park
Acidic polysaccharide isolated from Phellinus linteus induces nitric oxide-mediated tumoricidal activity of macrophages through protein tyrosine kinase and protein kinase C.
Biochemical and biophysical research communications 2003;309(2):399-407.
2003: Gi-Young Kim; Soon-Kew Park; Min-Ki Lee; Sang-Hwa Lee; Yang-Hyo Oh; Jong-Young Kwak; Sik Yoon; Jae-Dong Lee; Yeong-Min Park
Proteoglycan isolated from Phellinus linteus activates murine B lymphocytes via protein kinase C and protein tyrosine kinase.
International immunopharmacology 2003;3(9):1281-92.
2003: Gi-Young Kim; Hyung-Sik Park; Byong-Hyok Nam; Sang-Jun Lee; Jae-Dong Lee
Purification and characterization of acidic proteo-heteroglycan from the fruiting body of Phellinus linteus (Berk. & M.A. Curtis) Teng.
Bioresource technology 2003;89(1):81-7.
2003: Gi-Young Kim; Seung-Hoon Kim; Sue-Yun Hwang; Ho-Youn Kim; Yeong-Min Park; Soon-Kew Park; Min-Ki Lee; Sang-Hwa Lee; Tae-Ho Lee; Jae-Dong Lee
Oral administration of proteoglycan isolated from Phellinus linteus in the prevention and treatment of collagen-induced arthritis in mice.
Biological & pharmaceutical bulletin 2003;26(6):823-31.