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Peter Kim

Research Profile

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Physiology

Protein Folding

Phenomena

Chemicals & Drugs

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Publications

TOP 3
Joseph J Plecs; Pehr B Harbury; Peter S Kim; Thomas Alber
Structural test of the parameterized-backbone method for protein design.
Samuel K Sia; Peter S Kim
Protein grafting of an HIV-1-inhibiting epitope.
Samuel K Sia; Peter A Carr; Andrea G Cochran; Vladimir N Malashkevich; Peter S Kim
Short constrained peptides that inhibit HIV-1 entry.

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All Publications

2004: Joseph J Plecs; Pehr B Harbury; Peter S Kim; Thomas Alber
Structural test of the parameterized-backbone method for protein design.
Journal of molecular biology 2004;342(1):289-97.
2003: Samuel K Sia; Peter S Kim
Protein grafting of an HIV-1-inhibiting epitope.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9756-61.
2002: Samuel K Sia; Peter A Carr; Andrea G Cochran; Vladimir N Malashkevich; Peter S Kim
Short constrained peptides that inhibit HIV-1 entry.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(23):14664-9.
2002: Philip Bradley; Peter S Kim; Bonnie Berger
TRILOGY: Discovery of sequence-structure patterns across diverse proteins.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(13):8500-5.
2002: Yoshihisa Hagihara; Peter S Kim
Toward development of a screen to identify randomly encoded, foldable sequences.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):6619-24.
2002: Xun Zhao; Saghi Ghaffari; Harvey Lodish; Vladimir N Malashkevich; Peter S Kim
Structure of the Bcr-Abl oncoprotein oligomerization domain.
Nature structural biology 2002;9(2):117-20.
2001: Amy E Keating; Vladimir N Malashkevich; Bruce Tidor; Peter S Kim
Side-chain repacking calculations for predicting structures and stabilities of heterodimeric coiled coils.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):14825-30.
2001: B K Chen; I Rousso; S Shim; Peter S Kim
Efficient assembly of an HIV-1/MLV Gag-chimeric virus in murine cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15239-44.
2001: DM Eckert; Peter S Kim
Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide region.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11187-92.
2001: Samuel K Sia; Peter S Kim
A designed protein with packing between left-handed and right-handed helices.
Biochemistry 2001;40(30):8981-9.
2001: Vladimir N Malashkevich; M Singh; Peter S Kim
The trimer-of-hairpins motif in membrane fusion: Visna virus.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8502-6.
2001: D L Akey; Vladimir N Malashkevich; Peter S Kim
Buried polar residues in coiled-coil interfaces.
Biochemistry 2001;40(21):6352-60.
2001: M J Root; Michael S Kay; Peter S Kim
Protein design of an HIV-1 entry inhibitor.
Science (New York, N.Y.) 2001;291(5505):884-8.
2001: DM Eckert; Peter S Kim
Mechanisms of viral membrane fusion and its inhibition.
Annual review of biochemistry 2001;70():777-810.
2000: X Zhao; M Singh; Vladimir N Malashkevich; Peter S Kim
Structural characterization of the human respiratory syncytial virus fusion protein core.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14172-7.
2000: I Rousso; M B Mixon; B K Chen; Peter S Kim
Palmitoylation of the HIV-1 envelope glycoprotein is critical for viral infectivity.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(25):13523-5.
2000: John R S Newman; E Wolf; Peter S Kim
A computationally directed screen identifying interacting coiled coils from Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(24):13203-8.
2000: Y Kuroda; Peter S Kim
Folding of bovine pancreatic trypsin inhibitor (BPTI) variants in which almost half the residues are alanine.
Journal of molecular biology 2000;298(3):493-501.
1999: DM Eckert; Vladimir N Malashkevich; L H Hong; Peter A Carr; Peter S Kim
Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket.
Cell 1999;99(1):103-15.
1999: Christina Redfield; Brenda A Schulman; M A Milhollen; Peter S Kim; Christopher M Dobson
Alpha-lactalbumin forms a compact molten globule in the absence of disulfide bonds.
Nature structural biology 1999;6(10):948-52.
1999: Vladimir N Malashkevich; B J Schneider; M L McNally; M A Milhollen; J X Pang; Peter S Kim
Core structure of the envelope glycoprotein GP2 from Ebola virus at 1.9-A resolution.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):2662-7.
1999: E Wolf; Peter S Kim
Combinatorial codons: a computer program to approximate amino acid probabilities with biased nucleotide usage.
Protein science : a publication of the Protein Society 1999;8(3):680-8.
1998: DC Chan; C T Chutkowski; Peter S Kim
Evidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug target.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15613-7.
1998: DM Eckert; Vladimir N Malashkevich; Peter S Kim
Crystal structure of GCN4-pIQI, a trimeric coiled coil with buried polar residues.
Journal of molecular biology 1998;284(4):859-65.
1998: Pehr B Harbury; Joseph J Plecs; Bruce Tidor; Thomas Alber; Peter S Kim
High-resolution protein design with backbone freedom.
Science (New York, N.Y.) 1998;282(5393):1462-7.
1998: M G Oakley; Peter S Kim
A buried polar interaction can direct the relative orientation of helices in a coiled coil.
Biochemistry 1998;37(36):12603-10.
1998: Vladimir N Malashkevich; DC Chan; C T Chutkowski; Peter S Kim
Crystal structure of the simian immunodeficiency virus (SIV) gp41 core: conserved helical interactions underlie the broad inhibitory activity of gp41 peptides.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9134-9.
1998: DC Chan; Peter S Kim
HIV entry and its inhibition.
Cell 1998;93(5):681-4.
1997: L C Wu; Peter S Kim
Hydrophobic sequence minimization of the alpha-lactalbumin molten globule.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14314-9.
1997: C M Carr; C Chaudhry; Peter S Kim
Influenza hemagglutinin is spring-loaded by a metastable native conformation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14306-13.
1997: M Lu; Peter S Kim
A trimeric structural subdomain of the HIV-1 transmembrane glycoprotein.
Journal of biomolecular structure & dynamics 1997;15(3):465-71.
1997: Yang-Gyun Kim; Peter S Kim; A Herbert; Alexander Rich
Construction of a Z-DNA-specific restriction endonuclease.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(24):12875-9.
1997: K P Williams; X H Liu; Schumacher Ton; H Y Lin; D A Ausiello; Peter S Kim; David P Bartel
Bioactive and nuclease-resistant L-DNA ligand of vasopressin.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11285-90.
1997: Deborah Fass; R A Davey; C A Hamson; Peter S Kim; J M Cunningham; James M Berger
Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution.
Science (New York, N.Y.) 1997;277(5332):1662-6.
1997: Deborah Fass; S Blacklow; Peter S Kim; James M Berger
Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module.
Nature 1997;388(6643):691-3.
1997: Brenda A Schulman; Peter S Kim; Christopher M Dobson; Christina Redfield
A residue-specific NMR view of the non-cooperative unfolding of a molten globule.
Nature structural biology 1997;4(8):630-4.
1997: E Wolf; Peter S Kim; B Berger
MultiCoil: a program for predicting two- and three-stranded coiled coils.
Protein science : a publication of the Protein Society 1997;6(6):1179-89.
1997: DC Chan; D Fass; James M Berger; Peter S Kim
Core structure of gp41 from the HIV envelope glycoprotein.
Cell 1997;89(2):263-73.
1997: M G Oakley; Peter S Kim
Protein dissection of the antiparallel coiled coil from Escherichia coli seryl tRNA synthetase.
Biochemistry 1997;36(9):2544-9.
1997: C J McKnight; P T Matsudaira; Peter S Kim
NMR structure of the 35-residue villin headpiece subdomain.
Nature structural biology 1997;4(3):180-4.
1996: M Dadlez; Peter S Kim
Rapid formation of the native 14-38 disulfide bond in the early stages of BPTI folding.
Biochemistry 1996;35(50):16153-64.
1996: Stephen Xavier Skapek; J Rhee; Peter S Kim; Bennett Novitch; Andrew B Lassar
Cyclin-mediated inhibition of muscle gene expression via a mechanism that is independent of pRB hyperphosphorylation.
Molecular and cellular biology 1996;16(12):7043-53.
1996: Brenda A Schulman; Peter S Kim
Proline scanning mutagenesis of a molten globule reveals non-cooperative formation of a protein's overall topology.
Nature structural biology 1996;3(8):682-7.
1996: C J McKnight; D S Doering; P T Matsudaira; Peter S Kim
A thermostable 35-residue subdomain within villin headpiece.
Journal of molecular biology 1996;260(2):126-34.
1996: daniel minor; Peter S Kim
Context-dependent secondary structure formation of a designed protein sequence.
Nature 1996;380(6576):730-4.
1996: Schumacher Ton; L M Mayr; daniel minor; M A Milhollen; M W Burgess; Peter S Kim
Identification of D-peptide ligands through mirror-image phage display.
Science (New York, N.Y.) 1996;271(5257):1854-7.
1996: A G Cochran; Peter S Kim
Imitation of Escherichia coli aspartate receptor signaling in engineered dimers of the cytoplasmic domain.
Science (New York, N.Y.) 1996;271(5252):1113-6.
1996: L C Wu; Brenda A Schulman; Zheng-Yu Peng; Peter S Kim
Disulfide determinants of calcium-induced packing in alpha-lactalbumin.
Biochemistry 1996;35(3):859-63.
1995: J S Weissman; Peter S Kim
A kinetic explanation for the rearrangement pathway of BPTI folding.
Nature structural biology 1995;2(12):1123-30.
1995: M Lu; S C Blacklow; Peter S Kim
A trimeric structural domain of the HIV-1 transmembrane glycoprotein.
Nature structural biology 1995;2(12):1075-82.
1995: D Fass; Peter S Kim
Dissection of a retrovirus envelope protein reveals structural similarity to influenza hemagglutinin.
Current biology : CB 1995;5(12):1377-83.
1995: S C Blacklow; M Lu; Peter S Kim
A trimeric subdomain of the simian immunodeficiency virus envelope glycoprotein.
Biochemistry 1995;34(46):14955-62.
1995: Brenda A Schulman; Christina Redfield; Zheng-Yu Peng; Christopher M Dobson; Peter S Kim
Different subdomains are most protected from hydrogen exchange in the molten globule and native states of human alpha-lactalbumin.
Journal of molecular biology 1995;253(5):651-7.
1995: P B Harbury; Bruce Tidor; Peter S Kim
Repacking protein cores with backbone freedom: structure prediction for coiled coils.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(18):8408-12.
1995: Bonnie Berger; D B Wilson; E Wolf; T Tonchev; M Milla; Peter S Kim
Predicting coiled coils by use of pairwise residue correlations.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(18):8259-63.
1995: M Dadlez; Peter S Kim
A third native one-disulphide intermediate in the folding of bovine pancreatic trypsin inhibitor.
Nature structural biology 1995;2(8):674-9.
1995: Kevin J Lumb; Peter S Kim
A buried polar interaction imparts structural uniqueness in a designed heterodimeric coiled coil.
Biochemistry 1995;34(27):8642-8.
1995: M H Yu; J S Weissman; Peter S Kim
Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis.
Journal of molecular biology 1995;249(2):388-97.
1995: Zheng-Yu Peng; L C Wu; Brenda A Schulman; Peter S Kim
Does the molten globule have a native-like tertiary fold?
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1995;348(1323):43-7.
1995: Kevin J Lumb; Peter S Kim
Measurement of interhelical electrostatic interactions in the GCN4 leucine zipper.
Science (New York, N.Y.) 1995;268(5209):436-9.
1995: L C Wu; Zheng-Yu Peng; Peter S Kim
Bipartite structure of the alpha-lactalbumin molten globule.
Nature structural biology 1995;2(4):281-6.
1995: Zheng-Yu Peng; L C Wu; Peter S Kim
Local structural preferences in the alpha-lactalbumin molten globule.
Biochemistry 1995;34(10):3248-52.
1995: Paula J Booth; Sabine L Flitsch; L J Stern; D A Greenhalgh; Peter S Kim; H Gobind Khorana
Intermediates in the folding of the membrane protein bacteriorhodopsin.
Nature structural biology 1995;2(2):139-43.
1994: B A Schulman; Peter S Kim
Hydrogen exchange in BPTI variants that do not share a common disulfide bond.
Protein science : a publication of the Protein Society 1994;3(12):2226-32.
1994: Jonathan P Staley; Peter S Kim
Formation of a native-like subdomain in a partially folded intermediate of bovine pancreatic trypsin inhibitor.
Protein science : a publication of the Protein Society 1994;3(10):1822-32.
1994: daniel minor; Peter S Kim
Context is a major determinant of beta-sheet propensity.
Nature 1994;371(6494):264-7.
1994: P B Harbury; Peter S Kim; Thomas Alber
Crystal structure of an isoleucine-zipper trimer.
Nature 1994;371(6492):80-3.
1994: Zheng-Yu Peng; Peter S Kim
A protein dissection study of a molten globule.
Biochemistry 1994;33(8):2136-41.
1994: daniel minor; Peter S Kim
Measurement of the beta-sheet-forming propensities of amino acids.
Nature 1994;367(6464):660-3.
1993: P B Harbury; T Zhang; Peter S Kim; Thomas Alber
A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants.
Science (New York, N.Y.) 1993;262(5138):1401-7.
1993: E K O'Shea; Kevin J Lumb; Peter S Kim
Peptide 'Velcro': design of a heterodimeric coiled coil.
Current biology : CB 1993;3(10):658-67.
1993: J S Weissman; Peter S Kim
Efficient catalysis of disulphide bond rearrangements by protein disulphide isomerase.
Nature 1993;365(6442):185-8.
1993: C M Carr; Peter S Kim
A spring-loaded mechanism for the conformational change of influenza hemagglutinin.
Cell 1993;73(4):823-32.
1993: D J Lockhart; Peter S Kim
Electrostatic screening of charge and dipole interactions with the helix backbone.
Science (New York, N.Y.) 1993;260(5105):198-202.
1992: J S Weissman; Peter S Kim
The pro region of BPTI facilitates folding.
Cell 1992;71(5):841-51.
1992: J S Weissman; Peter S Kim
Kinetic role of nonnative species in the folding of bovine pancreatic trypsin inhibitor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(20):9900-4.
1992: D J Lockhart; Peter S Kim
Internal stark effect measurement of the electric field at the amino terminus of an alpha helix.
Science (New York, N.Y.) 1992;257(5072):947-51.
1992: Robert Talanian; C J McKnight; R Rutkowski; Peter S Kim
Minimum length of a sequence-specific DNA binding peptide.
Biochemistry 1992;31(30):6871-5.
1992: Jonathan P Staley; Peter S Kim
Complete folding of bovine pancreatic trypsin inhibitor with only a single disulfide bond.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(5):1519-23.
1992: E K O'Shea; R Rutkowski; Peter S Kim
Mechanism of specificity in the Fos-Jun oncoprotein heterodimer.
Cell 1992;68(4):699-708.
1991: E M Goodman; Peter S Kim
Periodicity of amide proton exchange rates in a coiled-coil leucine zipper peptide.
Biochemistry 1991;30(50):11615-20.
1991: T Y Lin; Peter S Kim
Evaluating the effects of a single amino acid substitution on both the native and denatured states of a protein.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10573-7.
1991: J S Weissman; Peter S Kim
Reexamination of the folding of BPTI: predominance of native intermediates.
Science (New York, N.Y.) 1991;253(5026):1386-93.
1991: Alan D Frankel; Peter S Kim
Modular structure of transcription factors: implications for gene regulation.
Cell 1991;65(5):717-9.
1990: J C Hu; E K O'Shea; Peter S Kim; Robert T Sauer
Sequence requirements for coiled-coils: analysis with lambda repressor-GCN4 leucine zipper fusions.
Science (New York, N.Y.) 1990;250(4986):1400-3.
1990: Robert Talanian; C J McKnight; Peter S Kim
Sequence-specific DNA binding by a short peptide dimer.
Science (New York, N.Y.) 1990;249(4970):769-71.
1990: Jonathan P Staley; Peter S Kim
Role of a subdomain in the folding of bovine pancreatic trypsin inhibitor.
Nature 1990;344(6267):685-8.
1990: T G Oas; L P McIntosh; E K O'Shea; F W Dahlquist; Peter S Kim
Secondary structure of a leucine zipper determined by nuclear magnetic resonance spectroscopy.
Biochemistry 1990;29(12):2891-4.
1989: E K O'Shea; R Rutkowski; W F Stafford; Peter S Kim
Preferential heterodimer formation by isolated leucine zippers from fos and jun.
Science (New York, N.Y.) 1989;245(4918):646-8.
1989: T Y Lin; Peter S Kim
Urea dependence of thiol-disulfide equilibria in thioredoxin: confirmation of the linkage relationship and a sensitive assay for structure.
Biochemistry 1989;28(12):5282-7.
1989: E M Goodman; Peter S Kim
Folding of a peptide corresponding to the alpha-helix in bovine pancreatic trypsin inhibitor.
Biochemistry 1989;28(10):4343-7.
1989: E K O'Shea; R Rutkowski; Peter S Kim
Evidence that the leucine zipper is a coiled coil.
Science (New York, N.Y.) 1989;243(4890):538-42.
1988: T G Oas; Peter S Kim
A peptide model of a protein folding intermediate.
Nature 1988;336(6194):42-8.