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Young-Wan Kim

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Young-Wan Kim; Ran Zhang; Hongming Chen; Stephen G Withers
O-glycoligases, a new category of glycoside bond-forming mutant glycosidases, catalyse facile syntheses of isoprimeverosides.
Omid Hekmat; Christine Florizone; Young-Wan Kim; Lindsay D Eltis; R Antony J Warren; Stephen G Withers
Specificity fingerprinting of retaining beta-1,4-glycanases in the Cellulomonas fimi secretome using two fluorescent mechanism-based probes.
Young-Wan Kim; Hong-Ming Chen; Jin Hyo Kim; Johannes Mullegger; Don J Mahuran; Stephen G Withers
Thioglycoligase-based assembly of thiodisaccharides: screening as beta-galactosidase inhibitors.

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All Publications

2010: Young-Wan Kim; Ran Zhang; Hongming Chen; Stephen G Withers
O-glycoligases, a new category of glycoside bond-forming mutant glycosidases, catalyse facile syntheses of isoprimeverosides.
Chemical communications (Cambridge, England) 2010;46(46):8725-7.
2007: Omid Hekmat; Christine Florizone; Young-Wan Kim; Lindsay D Eltis; R Antony J Warren; Stephen G Withers
Specificity fingerprinting of retaining beta-1,4-glycanases in the Cellulomonas fimi secretome using two fluorescent mechanism-based probes.
Chembiochem : a European journal of chemical biology 2007;8(17):2125-32.
2007: Young-Wan Kim; Hong-Ming Chen; Jin Hyo Kim; Johannes Mullegger; Don J Mahuran; Stephen G Withers
Thioglycoligase-based assembly of thiodisaccharides: screening as beta-galactosidase inhibitors.
Chembiochem : a European journal of chemical biology 2007;8(13):1495-9.
2006: Young-Wan Kim; Hongming Chen; Jin Hyo Kim; Stephen G Withers
Catalytic properties of a mutant beta-galactosidase from Xanthomonas manihotis engineered to synthesize galactosyl-thio-beta-1,3 and -beta-1,4-glycosides.
FEBS letters 2006;580(18):4377-81.
2006: Young-Wan Kim; David T Fox; Omid Hekmat; Terrence Kantner; Lawrence P McIntosh; R Antony J Warren; Stephen G Withers
Glycosynthase-based synthesis of xylo-oligosaccharides using an engineered retaining xylanase from Cellulomonas fimi.
Organic & biomolecular chemistry 2006;4(10):2025-32.
2006: Young-Wan Kim; Andrew L Lovering; Hongming Chen; Terrence Kantner; Lawrence P McIntosh; Natalie C J Strynadka; Stephen G Withers
Expanding the thioglycoligase strategy to the synthesis of alpha-linked thioglycosides allows structural investigation of the parent enzyme/substrate complex.
Journal of the American Chemical Society 2006;128(7):2202-3.
2005: Young-Wan Kim; Hongming Chen; Stephen G Withers
Enzymatic transglycosylation of xylose using a glycosynthase.
Carbohydrate research 2005;340(18):2735-41.
2005: Omid Hekmat; Young-Wan Kim; Spencer J Williams; Shouming He; Stephen G Withers
Active-site peptide "fingerprinting" of glycosidases in complex mixtures by mass spectrometry. Discovery of a novel retaining beta-1,4-glycanase in Cellulomonas fimi.
The Journal of biological chemistry 2005;280(42):35126-35.
2005: Andrew L Lovering; Seung Seo Lee; Young-Wan Kim; Stephen G Withers; Natalie C J Strynadka
Mechanistic and structural analysis of a family 31 alpha-glycosidase and its glycosyl-enzyme intermediate.
The Journal of biological chemistry 2005;280(3):2105-15.
2004: Young-Wan Kim; Seung Seo Lee; R Antony J Warren; Stephen G Withers
Directed evolution of a glycosynthase from Agrobacterium sp. increases its catalytic activity dramatically and expands its substrate repertoire.
The Journal of biological chemistry 2004;279(41):42787-93.