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Koji Kimata

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Hiroyasu Ogawa; Takashi Sato; Katsuji Shimizu; Nobuo Sugiura; Sonoko Hatano; Koji Kimata; Naoko Nagai; Hisashi Narimatsu; Hideto Watanabe
Chondroitin sulfate synthase-2 is necessary for chain extension of chondroitin sulfate but not critical for skeletal development.
Masao Nakamura; Masashi Suzuki; Yuriko Uehara; Masahiro Asada; Emi Honda; Koji Kimata; Naoko Nagai; Toru Imamura
Sulfated glycosaminoglycans are required for specific and sensitive fibroblast growth factor (FGF) 19 signaling via FGF receptor 4 and betaKlotho.
Takashi Sato; Takashi Kudo; Yuzuru Ikehara; Hiroyasu Ogawa; Tomoko Hirano; Katsue Kiyohara; Kozue Hagiwara; Akira Togayachi; Masatsugu Ema; Satoru Takahashi; Koji Kimata; Hideto Watanabe; Hisashi Narimatsu
Chondroitin sulfate N-acetylgalactosaminyltransferase 1 is necessary for normal endochondral ossification and aggrecan metabolism.

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2012: Hiroyasu Ogawa; Takashi Sato; Katsuji Shimizu; Nobuo Sugiura; Sonoko Hatano; Koji Kimata; Naoko Nagai; Hisashi Narimatsu; Hideto Watanabe
Chondroitin sulfate synthase-2 is necessary for chain extension of chondroitin sulfate but not critical for skeletal development.
PloS one 2012;7(8):e43806.
2011: Masao Nakamura; Masashi Suzuki; Yuriko Uehara; Masahiro Asada; Emi Honda; Koji Kimata; Naoko Nagai; Toru Imamura
Sulfated glycosaminoglycans are required for specific and sensitive fibroblast growth factor (FGF) 19 signaling via FGF receptor 4 and betaKlotho.
The Journal of biological chemistry 2011;286(30):26418-23.
2011: Takashi Sato; Takashi Kudo; Yuzuru Ikehara; Hiroyasu Ogawa; Tomoko Hirano; Katsue Kiyohara; Kozue Hagiwara; Akira Togayachi; Masatsugu Ema; Satoru Takahashi; Koji Kimata; Hideto Watanabe; Hisashi Narimatsu
Chondroitin sulfate N-acetylgalactosaminyltransferase 1 is necessary for normal endochondral ossification and aggrecan metabolism.
The Journal of biological chemistry 2011;286(7):5803-12.
2011: Hiromitsu Yabushita; Lisheng Zhuo; Naoki Itano; Keita Iwasaki; Kouhei Kanyama; Koji Kimata; Yukihiko Obayashi; Akihiko Wakatsuki
Clinicopathological Role of Serum-Derived Hyaluronan-Associated Protein (SHAP)-Hyaluronan Complex in Endometrial Cancer.
Obstetrics and gynecology international 2011;2011():739150.
2010: Hiroyasu Ogawa; Masafumi Shionyu; Nobuo Sugiura; Sonoko Hatano; Naoko Nagai; Yukihiko Kubota; Kiyoji Nishiwaki; Takashi Sato; Masanori Gotoh; Hisashi Narimatsu; Katsuji Shimizu; Koji Kimata; Hideto Watanabe
Chondroitin sulfate synthase-2/chondroitin polymerizing factor has two variants with distinct function.
The Journal of biological chemistry 2010;285(44):34155-67.
2010: Kanyamas Choocheep; Sonoko Hatano; Hidekazu Takagi; Hideto Watanabe; Koji Kimata; Prachya Kongtawelert; Hideto Watanabe
Versican facilitates chondrocyte differentiation and regulates joint morphogenesis.
The Journal of biological chemistry 2010;285(27):21114-25.
2010: Takashi Kobayashi; Hiroko Habuchi; Ken Nogami; Satoko Ashikari-Hada; Koji Tamura; Hiroyuki Ide; Koji Kimata
Functional analysis of chick heparan sulfate 6-O-sulfotransferases in limb bud development.
Development, growth & differentiation 2010;52(2):146-56.
2010: Nobuo Sugiura; Yuichi Baba; Yoshirou Kawaguchi; Toru Iwatani; Kiyoshi Suzuki; Takahiro Kusakabe; Kiwamu Yamagishi; Koji Kimata; Yoshimitsu Kakuta; Hideto Watanabe
Glucuronyltransferase activity of KfiC from Escherichia coli strain K5 requires association of KfiA: KfiC and KfiA are essential enzymes for production of K5 polysaccharide, N-acetylheparosan.
The Journal of biological chemistry 2010;285(3):1597-606.
2010: Long Zhu; Lisheng Zhuo; Koji Kimata; Etsuro Yamaguchi; Hideto Watanabe; Mark A Aronica; Vincent C Hascall; Kenji Baba
Deficiency in the serum-derived hyaluronan-associated protein-hyaluronan complex enhances airway hyperresponsiveness in a murine model of asthma.
International archives of allergy and immunology 2010;153(3):223-33.
2009: Keittisak Suwan; Kanyamas Choocheep; Sonoko Hatano; Prachya Kongtawelert; Koji Kimata; Hideto Watanabe
Versican/PG-M Assembles Hyaluronan into Extracellular Matrix and Inhibits CD44-mediated Signaling toward Premature Senescence in Embryonic Fibroblasts.
The Journal of biological chemistry 2009;284(13):8596-604.
2008: Jinsong Zhao; Masahiko Yoneda; Masayuki Takeyama; Osamu Miyaishi; Yoko Inoue; Takuya Kataoka; Akiko Ohno-Jinno; Zenzo Isogai; Koji Kimata; Masayoshi Iwaki; Masahiro Zako
Characterization of a motif for specific binding to hyaluronan in chicken SPACR.
Journal of neurochemistry 2008;106(3):1117-24.
2008: Nobuo Sugiura; Satoshi Shimokata; Toshikazu Minamisawa; Jun Hirabayashi; Koji Kimata; Hideto Watanabe
Sequential synthesis of chondroitin oligosaccharides by immobilized chondroitin polymerase mutants.
Glycoconjugate journal 2008;25(6):521-30.
2008: Akiko Ohno-Jinno; Zenzo Isogai; Masahiko Yoneda; Kenji Kasai; Osamu Miyaishi; Yoko Inoue; Takuya Kataoka; Jing-Song Zhao; Huili Li; Masayuki Takeyama; Douglas R Keene; Lynn Y Sakai; Koji Kimata; Masayoshi Iwaki; Masahiro Zako
Versican and fibrillin-1 form a major hyaluronan-binding complex in the ciliary body.
Investigative ophthalmology & visual science 2008;49(7):2870-7.
2008: Noriko Sugaya; Hiroko Habuchi; Naoko Nagai; Satoko Ashikari-Hada; Koji Kimata
6-O-sulfation of heparan sulfate differentially regulates various fibroblast growth factor-dependent signalings in culture.
The Journal of biological chemistry 2008;283(16):10366-76.
2008: Lisheng Zhuo; Koji Kimata
Structure and function of inter-alpha-trypsin inhibitor heavy chains.
Connective tissue research 2008;49(5):311-20.
2008: Long Zhu; Lisheng Zhuo; Hideto Watanabe; Koji Kimata
Equivalent involvement of inter-alpha-trypsin inhibitor heavy chain isoforms in forming covalent complexes with hyaluronan.
Connective tissue research 2008;49(1):48-55.
2007: Hideto Watanabe; Masafumi Shionyu; Tomoatsu Kimura; Koji Kimata; Hideto Watanabe
Splicing factor 3b subunit 4 binds BMPR-IA and inhibits osteochondral cell differentiation.
The Journal of biological chemistry 2007;282(28):20728-38.
2007: Takashi Kobayashi; Hiroko Habuchi; Koji Tamura; Hiroyuki Ide; Koji Kimata
Essential role of heparan sulfate 2-O-sulfotransferase in chick limb bud patterning and development.
The Journal of biological chemistry 2007;282(27):19589-97.
2007: Nobuo Sugiura; Satoshi Shimokata; Hideto Watanabe; Koji Kimata
MS analysis of chondroitin polymerization: effects of Mn2+ ions on the stability of UDP-sugars and chondroitin synthesis.
Analytical biochemistry 2007;365(1):62-73.
2007: Hiroko Habuchi; Naoko Nagai; Noriko Sugaya; Fukiko Atsumi; Richard L Stevens; Koji Kimata
Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation, and late embryonic lethality.
The Journal of biological chemistry 2007;282(21):15578-88.
2007: Naoko Nagai; Hiroko Habuchi; Shinobu Kitazume; Hidenao Toyoda; Yasuhiro Hashimoto; Koji Kimata
Regulation of heparan sulfate 6-O-sulfation by beta-secretase activity.
The Journal of biological chemistry 2007;282(20):14942-51.
2007: Hiroshi Koyama; Terumasa Hibi; Zenzo Isogai; Masahiko Yoneda; Minoru Fujimori; Jun Amano; Masatomo Kawakubo; Reiji Kannagi; Koji Kimata; Shun'ichiro Taniguchi; Naoki Itano
Hyperproduction of hyaluronan in neu-induced mammary tumor accelerates angiogenesis through stromal cell recruitment: possible involvement of versican/PG-M.
The American journal of pathology 2007;170(3):1086-99.
2007: Kenichiro Sakai; Koji Kimata; Takashi Sato; Masanori Gotoh; Hisashi Narimatsu; Kenichi Shinomiya; Hideto Watanabe
Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage.
The Journal of biological chemistry 2007;282(6):4152-61.
2006: Lisheng Zhuo; Akiko Kanamori; Reiji Kannagi; Naoki Itano; Jiwen Wu; Michinari Hamaguchi; Naoki Ishiguro; Koji Kimata
SHAP potentiates the CD44-mediated leukocyte adhesion to the hyaluronan substratum.
The Journal of biological chemistry 2006;281(29):20303-14.
2006: Kazu Matsumoto; Nobuhiro Kamiya; Keittisak Suwan; Fukiko Atsumi; Katsuji Shimizu; Tamayuki Shinomura; Yoshihiko Yamada; Koji Kimata; Hideto Watanabe
Identification and characterization of versican/PG-M aggregates in cartilage.
The Journal of biological chemistry 2006;281(26):18257-63.
2006: Yoko Inoue; Masahiko Yoneda; Jinsong Zhao; Osamu Miyaishi; Akiko Ohno-Jinno; Takuya Kataoka; Zenzo Isogai; Koji Kimata; Masayoshi Iwaki; Masahiro Zako
Molecular cloning and characterization of chick SPACRCAN.
The Journal of biological chemistry 2006;281(15):10381-8.
2006: Li Shen; Lisheng Zhuo; Akihiko Okumura; Tetsuya Ishikawa; Masahiko Miyachi; Yoshihiro Owa; Tohko Ishizawa; Nobuo Sugiura; Yoshihisa Nagata; Toshiaki Nonami; Shinichi Kakumu; Koji Kimata
The SHAP-hyaluronan complex in serum from patients with chronic liver diseases caused by hepatitis virus infection.
Hepatology research : the official journal of the Japan Society of Hepatology 2006;34(3):178-86.
2006: Nobuhiro Kamiya; Hideto Watanabe; Hiroko Habuchi; Hidekazu Takagi; Tamayuki Shinomura; Katsuji Shimizu; Koji Kimata
Versican/PG-M regulates chondrogenesis as an extracellular matrix molecule crucial for mesenchymal condensation.
The Journal of biological chemistry 2006;281(4):2390-400.
2006: Hiroko Habuchi; Osami Habuchi; Kenji Uchimura; Koji Kimata; Takashi Muramatsu
Determination of substrate specificity of sulfotransferases and glycosyltransferases (proteoglycans).
Methods in enzymology 2006;416():225-43.
2005: Satoko Ashikari-Hada; Hiroko Habuchi; Yutaka Kariya; Koji Kimata
Heparin regulates vascular endothelial growth factor165-dependent mitogenic activity, tube formation, and its receptor phosphorylation of human endothelial cells. Comparison of the effects of heparin and modified heparins.
The Journal of biological chemistry 2005;280(36):31508-15.
2005: Hiromitsu Yabushita; Tameko Kishida; Kanako Fusano; Kouhei Kanyama; Lisheng Zhuo; Naoki Itano; Koji Kimata; Masayoshi Noguchi
Role of hyaluronan and hyaluronan synthase in endometrial cancer.
Oncology reports 2005;13(6):1101-5.
2004: Hiromitsu Yabushita; Mari Noguchi; Tameko Kishida; Kanako Fusano; Yasuyuki Noguchi; Naoki Itano; Koji Kimata; Masayoshi Noguchi
Hyaluronan synthase expression in ovarian cancer.
Oncology reports 2004;12(4):739-43.
2004: Lisheng Zhuo; Vincent C Hascall; Koji Kimata
Inter-alpha-trypsin inhibitor, a covalent protein-glycosaminoglycan-protein complex.
The Journal of biological chemistry 2004;279(37):38079-82.
2004: Naoko Nagai; Hiroko Habuchi; Jeffrey D Esko; Koji Kimata
Stem domains of heparan sulfate 6-O-sulfotransferase are required for Golgi localization, oligomer formation and enzyme activity.
Journal of cell science 2004;117(Pt 15):3331-41.
2004: Naoki Itano; Takahiro Sawai; Fukiko Atsumi; Osamu Miyaishi; Shun'ichiro Taniguchi; Reiji Kannagi; Michinari Hamaguchi; Koji Kimata
Selective expression and functional characteristics of three mammalian hyaluronan synthases in oncogenic malignant transformation.
The Journal of biological chemistry 2004;279(18):18679-87.
2004: Satoko Ashikari-Hada; Hiroko Habuchi; Yutaka Kariya; Nobuyuki Itoh; Hari Reddi; Koji Kimata
Characterization of growth factor-binding structures in heparin/heparan sulfate using an octasaccharide library.
The Journal of biological chemistry 2004;279(13):12346-54.
2004: Ken Nogami; Hiroaki Suzuki; Hiroko Habuchi; Naoki Ishiguro; Hisashi Iwata; Koji Kimata
Distinctive expression patterns of heparan sulfate O-sulfotransferases and regional differences in heparan sulfate structure in chick limb buds.
The Journal of biological chemistry 2004;279(9):8219-29.
2004: Hiroko Habuchi; Osami Habuchi; Koji Kimata
Sulfation pattern in glycosaminoglycan: does it have a code?
Glycoconjugate journal 2004;21(1-2):47-52.
2004: Yoichi Yamada; Naoki Itano; Hisashi Narimatsu; Takashi Kudo; Kyoei Morozumi; Setsuo Hirohashi; Atsushi Ochiai; Minoru Ueda; Koji Kimata
Elevated transcript level of hyaluronan synthase1 gene correlates with poor prognosis of human colon cancer.
Clinical & experimental metastasis 2004;21(1):57-63.
2003: Kazu Matsumoto; Masafumi Shionyu; Mitiko Go; Katsuji Shimizu; Tamayuki Shinomura; Koji Kimata; Hideto Watanabe
Distinct interaction of versican/PG-M with hyaluronan and link protein.
The Journal of biological chemistry 2003;278(42):41205-12.
2003: Toshikazu Yada; Takashi Sato; Hiromi Kaseyama; Masanori Gotoh; Hiroko Iwasaki; Norihiro Kikuchi; Yeon-Dae Kwon; Akira Togayachi; Takashi Kudo; Hideto Watanabe; Hisashi Narimatsu; Koji Kimata
Chondroitin sulfate synthase-3. Molecular cloning and characterization.
The Journal of biological chemistry 2003;278(41):39711-25.
2003: Wannarat Yingsung; Lisheng Zhuo; Matthias Morgelin; Masahiko Yoneda; Daihei Kida; Hideto Watanabe; Naoki Ishiguro; Hisashi Iwata; Koji Kimata
Molecular heterogeneity of the SHAP-hyaluronan complex. Isolation and characterization of the complex in synovial fluid from patients with rheumatoid arthritis.
The Journal of biological chemistry 2003;278(35):32710-8.
2003: Toshikazu Yada; Masanori Gotoh; Takashi Sato; Masafumi Shionyu; Mitiko Go; Hiromi Kaseyama; Hiroko Iwasaki; Norihiro Kikuchi; Yeon-Dae Kwon; Akira Togayachi; Takashi Kudo; Hideto Watanabe; Hisashi Narimatsu; Koji Kimata
Chondroitin sulfate synthase-2. Molecular cloning and characterization of a novel human glycosyltransferase homologous to chondroitin sulfate glucuronyltransferase, which has dual enzymatic activities.
The Journal of biological chemistry 2003;278(32):30235-47.
2003: Hideo Mochizuki; Keiichi Yoshida; Masanori Gotoh; Shigemi Sugioka; Norihiro Kikuchi; Yeon-Dae Kwon; Akira Tawada; Kennichi Maeyama; Niro Inaba; Toru Hiruma; Koji Kimata; Hisashi Narimatsu
Characterization of a heparan sulfate 3-O-sulfotransferase-5, an enzyme synthesizing a tetrasulfated disaccharide.
The Journal of biological chemistry 2003;278(29):26780-7.
2003: Kiwamu Yamagishi; Kiyoshi Suzuki; Kyoko Imai; Hideo Mochizuki; Kiyoshi Morikawa; Mamoru Kyogashima; Koji Kimata; Hideto Watanabe
Purification, characterization, and molecular cloning of a novel keratan sulfate hydrolase, endo-beta-N-acetylglucosaminidase, from Bacillus circulans.
The Journal of biological chemistry 2003;278(28):25766-72.
2003: Hiroko Habuchi; Goichiro Miyake; Ken Nogami; Asato Kuroiwa; Yoichi Matsuda; Marion Kusche-Gullberg; Osami Habuchi; Masayuki Tanaka; Koji Kimata
Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties.
The Biochemical journal 2003;371(Pt 1):131-42.
2003: Takashi Sato; Masanori Gotoh; Katsue Kiyohara; Tomohiro Akashima; Hiroko Iwasaki; Akihiko Kameyama; Hideo Mochizuki; Toshikazu Yada; Niro Inaba; Akira Togayachi; Takashi Kudo; Masahiro Asada; Hideto Watanabe; Toru Imamura; Koji Kimata; Hisashi Narimatsu
Differential roles of two N-acetylgalactosaminyltransferases, CSGalNAcT-1, and a novel enzyme, CSGalNAcT-2. Initiation and elongation in synthesis of chondroitin sulfate.
The Journal of biological chemistry 2003;278(5):3063-71.
2002: Hiroo Sawada; Tamayuki Shinomura; Koji Kimata; Jun Takeuchi; Takuo Tsuji; Hideto Watanabe
Characterization of an anti-decorin monoclonal antibody, and its utility.
Journal of biochemistry 2002;132(6):997-1002.
2002: Masanori Gotoh; Takashi Sato; Tomohiro Akashima; Hiroko Iwasaki; Akihiko Kameyama; Hideo Mochizuki; Toshikazu Yada; Niro Inaba; Yan Zhang; Norihiro Kikuchi; Yeon-Dae Kwon; Akira Togayachi; Takashi Kudo; Shoko Nishihara; Hideto Watanabe; Koji Kimata; Hisashi Narimatsu
Enzymatic synthesis of chondroitin with a novel chondroitin sulfate N-acetylgalactosaminyltransferase that transfers N-acetylgalactosamine to glucuronic acid in initiation and elongation of chondroitin sulfate synthesis.
The Journal of biological chemistry 2002;277(41):38189-96.
2002: Masanori Gotoh; Toshikazu Yada; Takashi Sato; Tomohiro Akashima; Hiroko Iwasaki; Hideo Mochizuki; Niro Inaba; Akira Togayachi; Takashi Kudo; Hideto Watanabe; Koji Kimata; Hisashi Narimatsu
Molecular cloning and characterization of a novel chondroitin sulfate glucuronyltransferase that transfers glucuronic acid to N-acetylgalactosamine.
The Journal of biological chemistry 2002;277(41):38179-88.
2002: Naoki Itano; Koji Kimata
Mammalian hyaluronan synthases.
IUBMB life 2002;54(4):195-9.
2002: Nobuhiro Kamiya; Akitoshi Jikko; Koji Kimata; Caroline Damsky; Katsuji Shimizu; Hideto Watanabe
Establishment of a novel chondrocytic cell line N1511 derived from p53-null mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(10):1832-42.
2002: Hidekazu Takagi; Yasushi Asano; Naomi Yamakawa; Isamu Matsumoto; Koji Kimata
Annexin 6 is a putative cell surface receptor for chondroitin sulfate chains.
Journal of cell science 2002;115(Pt 16):3309-18.
2002: Masahiro Zako; Masayoshi Iwaki; Masahiko Yoneda; Osamu Miyaishi; Jinsong Zhao; Yasuhiko Suzuki; Makoto Takeuchi; Goichiro Miyake; Hiroshi Ikagawa; Koji Kimata
Molecular cloning and characterization of chick sialoprotein associated with cones and rods, a developmentally regulated glycoprotein of interphotoreceptor matrix.
The Journal of biological chemistry 2002;277(28):25592-600.
2002: Toshio Ninomiya; Nobuo Sugiura; Akira Tawada; Kazunori Sugimoto; Hideto Watanabe; Koji Kimata
Molecular cloning and characterization of chondroitin polymerase from Escherichia coli strain K4.
The Journal of biological chemistry 2002;277(24):21567-75.
2002: Lisheng Zhuo; Antonietta Salustri; Koji Kimata
A physiological function of serum proteoglycan bikunin: the chondroitin sulfate moiety plays a central role.
Glycoconjugate journal 2002;19(4-5):241-7.
2002: Naoki Itano; Fukiko Atsumi; Takahiro Sawai; Yoichi Yamada; Osamu Miyaishi; Takeshi Senga; Michinari Hamaguchi; Koji Kimata
Abnormal accumulation of hyaluronan matrix diminishes contact inhibition of cell growth and promotes cell migration.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3609-14.
2001: Hiroko Habuchi; Koji Kimata
[Heparan sulfate proteoglycans mediating the epithelial and mesenchymal interaction].
Seikagaku. The Journal of Japanese Biochemical Society 2001;73(10):1246-56.
2001: Lisheng Zhuo; Koji Kimata
Cumulus oophorus extracellular matrix: its construction and regulation.
Cell structure and function 2001;26(4):189-96.
2001: Koji Kimata; Lisheng Zhuo
[Dissecting the structure and function of the extracellular hyaluronan-rich matrix by gene manipulation].
Seikagaku. The Journal of Japanese Biochemical Society 2001;73(6):429-38.
2001: Lisheng Zhuo; Masahiko Yoneda; M Zhao; W Yingsung; N Yoshida; Y Kitagawa; K Kawamura; T Suzuki; Koji Kimata
Defect in SHAP-hyaluronan complex causes severe female infertility. A study by inactivation of the bikunin gene in mice.
The Journal of biological chemistry 2001;276(11):7693-6.
2000: Hiroko Habuchi; M Tanaka; Osami Habuchi; K Yoshida; H Suzuki; K Ban; Koji Kimata
The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine.
The Journal of biological chemistry 2000;275(4):2859-68.
2000: M Yoshida; Naoki Itano; Yoichi Yamada; Koji Kimata
In vitro synthesis of hyaluronan by a single protein derived from mouse HAS1 gene and characterization of amino acid residues essential for the activity.
The Journal of biological chemistry 2000;275(1):497-506.
1999: Naoki Itano; Yoichi Yamada; M Yoshida; Koji Kimata
[Cancer metastasis and extracellular matrix].
Gan to kagaku ryoho. Cancer & chemotherapy 1999;26(11):1663-8.
1999: Yoichi Yamada; Naoki Itano; Hisashi Narimatsu; Takashi Kudo; Setsuo Hirohashi; A Ochiai; A Niimi; Minoru Ueda; Koji Kimata
Receptor for hyaluronan-mediated motility and CD44 expressions in colon cancer assessed by quantitative analysis using real-time reverse transcriptase-polymerase chain reaction.
Japanese journal of cancer research : Gann 1999;90(9):987-92.
1999: Naoki Itano; Takahiro Sawai; M Yoshida; P Lenas; Yoichi Yamada; M Imagawa; Tamayuki Shinomura; Michinari Hamaguchi; Y Yoshida; Y Ohnuki; S Miyauchi; AP Spicer; John A McDonald; Koji Kimata
Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties.
The Journal of biological chemistry 1999;274(35):25085-92.
1999: D Kida; Masahiko Yoneda; S Miyaura; T Ishimaru; Y Yoshida; T Ito; Naoki Ishiguro; H Iwata; Koji Kimata
The SHAP-HA complex in sera from patients with rheumatoid arthritis and osteoarthritis.
The Journal of rheumatology 1999;26(6):1230-8.
1999: Naoki Itano; Takahiro Sawai; Osamu Miyaishi; Koji Kimata
Relationship between hyaluronan production and metastatic potential of mouse mammary carcinoma cells.
Cancer research 1999;59(10):2499-504.
1998: Naoki Itano; M Yoshida; Koji Kimata
[Hyaluronan synthase: functional analysis of hyaluronan by gene modification].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(16 Suppl):2387-93.
1998: Naoki Itano; Koji Kimata
[Hyaluronan synthase: a scenario for remodeling the extracellular matrix].
Seikagaku. The Journal of Japanese Biochemical Society 1998;70(9):1171-5.
1998: Y Iwata; Tamayuki Shinomura; K Kurita; Masahiro Zako; Koji Kimata
The gene structure and organization of mouse PG-Lb, a small chondroitin/dermatan sulphate proteoglycan.
The Biochemical journal 1998;331 ( Pt 3)():959-64.
1998: Hiroko Habuchi; M Kobayashi; Koji Kimata
Molecular characterization and expression of heparan-sulfate 6-sulfotransferase. Complete cDNA cloning in human and partial cloning in Chinese hamster ovary cells.
The Journal of biological chemistry 1998;273(15):9208-13.
1998: Yoichi Yamada; Naoki Itano; Masahiro Zako; M Yoshida; P Lenas; A Niimi; Minoru Ueda; Koji Kimata
The gene structure and promoter sequence of mouse hyaluronan synthase 1.
The Biochemical journal 1998;330 ( Pt 3)():1223-7.
1997: Masahiro Zako; Tamayuki Shinomura; Osamu Miyaishi; M Iwaki; Koji Kimata
Transient expression of PG-M/versican, a large chondroitin sulfate proteoglycan in developing chicken retina.
Journal of neurochemistry 1997;69(5):2155-61.
1997: M Kobayashi; Hiroko Habuchi; Masahiko Yoneda; Osami Habuchi; Koji Kimata
Molecular cloning and expression of Chinese hamster ovary cell heparan-sulfate 2-sulfotransferase.
The Journal of biological chemistry 1997;272(21):13980-5.
1997: AP Spicer; Michael F Seldin; A S Olsen; N Brown; D E Wells; N A Doggett; Naoki Itano; Koji Kimata; J Inazawa; John A McDonald
Chromosomal localization of the human and mouse hyaluronan synthase genes.
Genomics 1997;41(3):493-7.
1997: Masahiro Zako; Tamayuki Shinomura; Koji Kimata
Alternative splicing of the unique "PLUS" domain of chicken PG-M/versican is developmentally regulated.
The Journal of biological chemistry 1997;272(14):9325-31.
1996: Yoshiya Tanaka; Koji Kimata; A Wake; Shinichiro Mine; Isao Morimoto; N Yamakawa; Hiroko Habuchi; S Ashikari; H Yamamoto; K Sakurai; K Yoshida; S Suzuki; Sumiya Eto
Heparan sulfate proteoglycan on leukemic cells is primarily involved in integrin triggering and its mediated adhesion to endothelial cells.
The Journal of experimental medicine 1996;184(5):1987-97.
1996: K Kurita; Tamayuki Shinomura; M Ujita; Masahiro Zako; D Kida; H Iwata; Koji Kimata
Occurrence of PG-Lb, a leucine-rich small chondroitin/dermatan sulphate proteoglycan in mammalian epiphyseal cartilage: molecular cloning and sequence analysis of the mouse cDNA.
The Biochemical journal 1996;318 ( Pt 3)():909-14.
1996: T Yada; N Koide; Koji Kimata
Transient accumulation of perisinusoidal chondroitin sulfate proteoglycans during liver regeneration and development.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1996;44(9):969-80.
1996: M Takanosu; Hajime Amasaki; Shigeji Matsumoto; Koji Kimata
Distribution of chondroitin sulphate proteoglycans and peanut agglutinin-binding molecules during bovine fetal palatine ridge formation.
Journal of anatomy 1996;189 ( Pt 1)():109-15.
1996: Naoki Itano; Koji Kimata
Molecular cloning of human hyaluronan synthase.
Biochemical and biophysical research communications 1996;222(3):816-20.
1996: Naoki Itano; Koji Kimata
Expression cloning and molecular characterization of HAS protein, a eukaryotic hyaluronan synthase.
The Journal of biological chemistry 1996;271(17):9875-8.
1996: M Kobayashi; Hiroko Habuchi; Osami Habuchi; M Saito; Koji Kimata
Purification and characterization of heparan sulfate 2-sulfotransferase from cultured Chinese hamster ovary cells.
The Journal of biological chemistry 1996;271(13):7645-53.
1995: S Ashikari; Hiroko Habuchi; Koji Kimata
Characterization of heparan sulfate oligosaccharides that bind to hepatocyte growth factor.
The Journal of biological chemistry 1995;270(49):29586-93.
1995: M Zhao; Masahiko Yoneda; Y Ohashi; S Kurono; H Iwata; Y Ohnuki; Koji Kimata
Evidence for the covalent binding of SHAP, heavy chains of inter-alpha-trypsin inhibitor, to hyaluronan.
The Journal of biological chemistry 1995;270(44):26657-63.
1995: N Sugiura; S Iwasaki; S Aoki; Y Hori; K Sakurai; S Suzuki; Koji Kimata
Suppression of pannus-like extension of synovial cells by lipid-derivatized chondroitin sulphate: in vitro and in vivo studies using Escherichia coli-induced arthritic rabbits.
International journal of experimental pathology 1995;76(5):369-79.
1995: Masakazu Fukuta; Kenji Uchimura; K Nakashima; M Kato; Koji Kimata; T Shinomura; Osami Habuchi
Molecular cloning and expression of chick chondrocyte chondroitin 6-sulfotransferase.
The Journal of biological chemistry 1995;270(31):18575-80.
1995: M Ujita; Tamayuki Shinomura; Koji Kimata
Molecular cloning of the mouse osteoglycin-encoding gene.
Gene 1995;158(2):237-40.
1995: Masahiko Yoneda; Koji Kimata
[Hyaluronan-rich extracellular matrix. A role of inter alpha-trypsin inhibitor, serum derived proteoglycan].
Seikagaku. The Journal of Japanese Biochemical Society 1995;67(6):458-65.
1995: Tamayuki Shinomura; Masahiro Zako; K Ito; M Ujita; Koji Kimata
The gene structure and organization of mouse PG-M, a large chondroitin sulfate proteoglycan. Genomic background for the generation of multiple PG-M transcripts.
The Journal of biological chemistry 1995;270(17):10328-33.
1995: Hiroko Habuchi; Osami Habuchi; Koji Kimata
Purification and characterization of heparan sulfate 6-sulfotransferase from the culture medium of Chinese hamster ovary cells.
The Journal of biological chemistry 1995;270(8):4172-9.
1995: Masahiro Zako; Tamayuki Shinomura; M Ujita; K Ito; Koji Kimata
Expression of PG-M(V3), an alternatively spliced form of PG-M without a chondroitin sulfate attachment in region in mouse and human tissues.
The Journal of biological chemistry 1995;270(8):3914-8.
1995: K Ito; Tamayuki Shinomura; Masahiro Zako; M Ujita; Koji Kimata
Multiple forms of mouse PG-M, a large chondroitin sulfate proteoglycan generated by alternative splicing.
The Journal of biological chemistry 1995;270(2):958-65.
1994: M Ujita; Tamayuki Shinomura; K Ito; Y Kitagawa; Koji Kimata
Expression and binding activity of the carboxyl-terminal portion of the core protein of PG-M, a large chondroitin sulfate proteoglycan.
The Journal of biological chemistry 1994;269(44):27603-9.
1994: M Yamagata; Koji Kimata
Repression of a malignant cell-substratum adhesion phenotype by inhibiting the production of the anti-adhesive proteoglycan, PG-M/versican.
Journal of cell science 1994;107 ( Pt 9)():2581-90.
1994: N Sugiura; Koji Kimata
Syntheses and functions of neoproteoglycans: lipid-derivatized chondroitin sulfate with antiadhesion activity.
Methods in enzymology 1994;247():362-73.
1993: L Huang; Masahiko Yoneda; Koji Kimata
A serum-derived hyaluronan-associated protein (SHAP) is the heavy chain of the inter alpha-trypsin inhibitor.
The Journal of biological chemistry 1993;268(35):26725-30.
1993: M Yamagata; S Saga; M Kato; M Bernfield; Koji Kimata
Selective distributions of proteoglycans and their ligands in pericellular matrix of cultured fibroblasts. Implications for their roles in cell-substratum adhesion.
Journal of cell science 1993;106 ( Pt 1)():55-65.
1993: N Sugiura; K Sakurai; Y Hori; K Karasawa; S Suzuki; Koji Kimata
Preparation of lipid-derivatized glycosaminoglycans to probe a regulatory function of the carbohydrate moieties of proteoglycans in cell-matrix interaction.
The Journal of biological chemistry 1993;268(21):15779-87.
1993: Tamayuki Shinomura; Y Nishida; K Ito; Koji Kimata
cDNA cloning of PG-M, a large chondroitin sulfate proteoglycan expressed during chondrogenesis in chick limb buds. Alternative spliced multiforms of PG-M and their relationships to versican.
The Journal of biological chemistry 1993;268(19):14461-9.
1993: M Yamagata; Tamayuki Shinomura; Koji Kimata
Tissue variation of two large chondroitin sulfate proteoglycans (PG-M/versican and PG-H/aggrecan) in chick embryos.
Anatomy and embryology 1993;187(5):433-44.
1992: Hiroko Habuchi; S Suzuki; T Saito; T Tamura; T Harada; K Yoshida; Koji Kimata
Structure of a heparan sulphate oligosaccharide that binds to basic fibroblast growth factor.
The Biochemical journal 1992;285 ( Pt 3)():805-13.
1992: Koji Kimata
[Cartilage differentiation and its abnormality].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1992;37(11 Suppl):1847-57.
1992: M Arai; T Yada; S Suzuki; Koji Kimata
Isolation and characterization of type IX collagen-proteoglycan from the Swarm rat chondrosarcoma.
Biochimica et biophysica acta 1992;1117(1):60-70.
1992: T Yada; M Arai; S Suzuki; Koji Kimata
Occurrence of collagen and proteoglycan forms of type IX collagen in chick embryo cartilage. Production and characterization of a collagen form-specific antibody.
The Journal of biological chemistry 1992;267(13):9391-7.
1992: Tamayuki Shinomura; Koji Kimata
Proteoglycan-Lb, a small dermatan sulfate proteoglycan expressed in embryonic chick epiphyseal cartilage, is structurally related to osteoinductive factor.
The Journal of biological chemistry 1992;267(2):1265-70.
1992: M Yamagata; Koji Kimata
[Chimeric collagens: functional modulators for major collagen fibrils].
Seikagaku. The Journal of Japanese Biochemical Society 1992;64(1):26-32.
1991: T Tsukahara; M Okamura; S Suzuki; H Iwata; T Miura; Koji Kimata
Enhanced expression of fibronectin by cmd/cmd chondrocytes and its modulation by exogenously added proteoglycan.
Journal of cell science 1991;100 ( Pt 2)():387-95.
1990: T Yada; S Suzuki; K Kobayashi; M Kobayashi; T Hoshino; K Horie; Koji Kimata
Occurrence in chick embryo vitreous humor of a type IX collagen proteoglycan with an extraordinarily large chondroitin sulfate chain and short alpha 1 polypeptide.
The Journal of biological chemistry 1990;265(12):6992-9.
1990: H Morita; T Takeuchi; S Suzuki; K Maeda; K Yamada; G Eguchi; Koji Kimata
Aortic endothelial cells synthesize a large chondroitin sulphate proteoglycan capable of binding to hyaluronate.
The Biochemical journal 1990;265(1):61-8.
1989: M Yamagata; S Suzuki; S K Akiyama; K M Yamada; Koji Kimata
Regulation of cell-substrate adhesion by proteoglycans immobilized on extracellular substrates.
The Journal of biological chemistry 1989;264(14):8012-8.