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Ian Kimber

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David A Basketter; Florence G Burleson; Gary R Burleson; Ian R White; Ian Kimber
Dimethylfumarate: potency prediction and clinical experience.
Jean G Sathish; Swaminathan Sethu; Jennifer Sims; Meena Subramanyam; Marque D Todd; Jan Willem Van Der Laan; Richard J Weaver; Munir Pirmohamed; Gabriele Reichmann; Marie-Christine Bielsky; Lolke de Haan; Neil S French; Karthik Govindappa; James Green; Christopher E M Griffiths; Stephen Holgate; David Jones; Ian Kimber; Jonathan Moggs; Dean J Naisbitt; B Kevin Park
Challenges and approaches for the development of safer immunomodulatory biologics.
David A Basketter; Ian Kimber
Allergic contact dermatitis: is the reactive chemistry of skin sensitizers the whole story?

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All Publications

2013: David A Basketter; Florence G Burleson; Gary R Burleson; Ian R White; Ian Kimber
Dimethylfumarate: potency prediction and clinical experience.
Contact dermatitis 2013;68(5):269-72.
2013: Jean G Sathish; Swaminathan Sethu; Jennifer Sims; Meena Subramanyam; Marque D Todd; Jan Willem Van Der Laan; Richard J Weaver; Munir Pirmohamed; Gabriele Reichmann; Marie-Christine Bielsky; Lolke de Haan; Neil S French; Karthik Govindappa; James Green; Christopher E M Griffiths; Stephen Holgate; David Jones; Ian Kimber; Jonathan Moggs; Dean J Naisbitt; B Kevin Park
Challenges and approaches for the development of safer immunomodulatory biologics.
Nature reviews. Drug discovery 2013;12(4):306-24.
2013: David A Basketter; Ian Kimber
Allergic contact dermatitis: is the reactive chemistry of skin sensitizers the whole story?
Contact dermatitis 2013;68(4):244-5.
2013: John P McFadden; P Puangpet; David A Basketter; Rebecca J Dearman; Ian Kimber
Why does allergic contact dermatitis exist?
The British journal of dermatology 2013;168(4):692-9.
2013: Ian Kimber; Raymond Pieters
Household chemicals, immune function, and allergy: A commentary.
Journal of immunotoxicology 2013;10(2):169-72.
2013: Ian Kimber; Rebecca J Dearman; David A Basketter
Dendritic cells and the assessment in vitro of skin sensitizing potential.
Cutaneous and ocular toxicology 2013;32(1):54-9.
2013: Rachael J Almond; Aristotelis Antonopoulos; Anne Dell; Brian F Flanagan; Stuart M Haslam; Ian Kimber; Rebecca J Dearman
Differential immunogenicity and allergenicity of native and recombinant human lactoferrins: role of glycosylation.
European journal of immunology 2013;43(1):170-81.
2012: Rachael J Almond; Brian F Flanagan; Ian Kimber; Rebecca J Dearman
Influence of protein expression system on elicitation of IgE antibody responses: experience with lactoferrin.
Toxicology 2012;301(1-3):50-7.
2012: J McFadden; A V Powles; L Fry; Ian Kimber
Concepts in psoriasis: psoriasis and the extracellular matrix.
The British journal of dermatology 2012;167(5):980-6.
2012: Ian Kimber; Stefan F Martin; Mark A Travis; Rebecca J Dearman
Immunoregulation of skin sensitization and regulatory T cells.
Contact dermatitis 2012;67(4):179-83.
2012: Jon F Lalko; Anne Marie Api; Leslie M Foertsch; G Frank Gerberick; Ian Kimber; Rebecca J Dearman
The direct peptide reactivity assay: selectivity of chemical respiratory allergens.
Toxicological sciences : an official journal of the Society of Toxicology 2012;129(2):421-31.
2012: David A Basketter; John P McFadden; Ian Kimber
Assessing the severity of allergic reactions: a regulatory dilemma.
Contact dermatitis 2012;67(1):3-8.
2012: David W Roberts; David Basketter; Ian Kimber; John McFadden; Jonathan White; Ian R White
Sodium metabisulfite as a contact allergen--an example of a rare chemical mechanism for protein modification.
Contact dermatitis 2012;66(3):123-7.
2012: Costanza Rovida; Cindy Ryan; David Basketter; Serena Cinelli; Rebecca Dearman; Ian Kimber
The local lymph node assay (LLNA).
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2012;Chapter 20():Unit 20.7.
2011: David A Basketter; Ian Kimber
Skin irritation, false positives and the local lymph node assay: a guideline issue?
Regulatory toxicology and pharmacology : RTP 2011;61(1):137-40.
2011: Ian Kimber; Colin Humphris; Carl Westmoreland; Nathalie Alepee; Gianni Dal Negro; Irene Manou
Computational chemistry, systems biology and toxicology. Harnessing the chemistry of life: revolutionizing toxicology. a commentary.
Journal of applied toxicology : JAT 2011;31(3):206-9.
2011: John P McFadden; Rebecca J Dearman; J M L White; David A Basketter; Ian Kimber
The Hapten-Atopy hypothesis II: the 'cutaneous hapten paradox'.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2011;41(3):327-37.
2011: Ian Kimber; David A Basketter; G Frank Gerberick; Cindy A Ryan; Rebecca J Dearman
Chemical allergy: translating biology into hazard characterization.
Toxicological sciences : an official journal of the Society of Toxicology 2011;120 Suppl 1():S238-68.
2011: Ian Kimber; David A Basketter; John P McFadden; Rebecca J Dearman
Characterization of skin sensitizing chemicals: a lesson learnt from nickel allergy.
Journal of immunotoxicology 2011;8(1):1-2.
2010: Frances L Shaw; Marie Cumberbatch; C Elise Kleyn; Rummana Begum; Rebecca J Dearman; Ian Kimber; Christopher E M Griffiths
Langerhans cell mobilization distinguishes between early-onset and late-onset psoriasis.
The Journal of investigative dermatology 2010;130(7):1940-2.
2010: Ian Kimber; Rebecca J Dearman
An assessment of the ability of phthalates to influence immune and allergic responses.
Toxicology 2010;271(3):73-82.
2010: Ian Kimber; David A Basketter; Rebecca J Dearman
Chemical allergens--what are the issues?
Toxicology 2010;268(3):139-42.
2010: Ian Kimber; Rebecca J Dearman
The local lymph node assay and skin sensitization testing.
Methods in molecular biology (Clifton, N.J.) 2010;598():221-31.
2009: Ian Kimber; Marie Cumberbatch; Rebecca J Dearman
Langerhans cell migration: not necessarily always at the center of the skin sensitization universe.
The Journal of investigative dermatology 2009;129(8):1852-3.
2009: Rebecca J Dearman; Ian Kimber
Animal models of protein allergenicity: potential benefits, pitfalls and challenges.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(4):458-68.
2009: Rebecca Jane Dearman; Catherine Jean Betts; Helen Theresa Caddick; Ian Kimber
Cytokine profiling of chemical allergens in mice: impact of mitogen on selectivity of response.
Journal of applied toxicology : JAT 2009;29(3):233-41.
2009: Rebecca J Dearman; Marie Cumberbatch; Gavin Maxwell; David A Basketter; Ian Kimber
Toll-like receptor ligand activation of murine bone marrow-derived dendritic cells.
Immunology 2009;126(4):475-84.
2009: Rebecca Jane Dearman; Catherine Jean Betts; Lorna Beresford; Laura Bailey; Helen Theresa Caddick; Ian Kimber
Butyl benzyl phthalate: effects on immune responses to ovalbumin in mice.
Journal of applied toxicology : JAT 2009;29(2):118-25.
2009: Ian Kimber
6 Conclusions.
Human & experimental toxicology 2009;28(2-3):163.
2009: David A Basketter; John F McFadden; Frank Gerberick; Amanda Cockshott; Ian Kimber
Nothing is perfect, not even the local lymph node assay: a commentary and the implications for REACH.
Contact dermatitis 2009;60(2):65-9.
2008: Rebecca J Dearman; Marie Cumberbatch; Craig Portsmouth; Gavin Maxwell; David A Basketter; Ian Kimber
Synergistic effects of chemical insult and toll-like receptor ligands on dendritic cell activation.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(8):1927-34.
2008: Ian Kimber; David A Basketter
Thresholds, dose-response relationships and dose metrics in allergic contact dermatitis.
The British journal of dermatology 2008;159(6):1380-1; author reply 1381-2.
2008: Rebecca Jane Dearman; Catherine Jean Betts; Helen Theresa Caddick; Brian Francis Flanagan; Ian Kimber
Cytokine profiling of chemical allergens in mice: measurement of message versus protein.
Toxicology 2008;252(1-3):17-25.
2008: Ian Kimber; Rebecca J Dearman; David A Basketter; Cindy A Ryan; G Frank Gerberick; Pauline M McNamee; Jon Lalko; Anne Marie Api
Dose metrics in the acquisition of skin sensitization: thresholds and importance of dose per unit area.
Regulatory toxicology and pharmacology : RTP 2008;52(1):39-45.
2008: Niki Tsakiri; Ian Kimber; Nancy J Rothwell; Emmanuel Pinteaux
Differential effects of interleukin-1 alpha and beta on interleukin-6 and chemokine synthesis in neurones.
Molecular and cellular neurosciences 2008;38(2):259-65.
2008: David A Basketter; Amanda Cockshott; Emanuela Corsini; G Frank Gerberick; Kenji Idehara; Ian Kimber; Henk Van Loveren; Joanna Matheson; Annette Mehling; Takashi Omori; Costanza Rovida; Takashi Sozu; Masahiro Takeyoshi; Silvia Casati
An evaluation of performance standards and non-radioactive endpoints for the local lymph node assay. The report and recommendations of ECVAM Workshop 65.
Alternatives to laboratory animals : ATLA 2008;36(2):243-57.
2008: C Elise Kleyn; Laura Schneider; Rosita Saraceno; Cristina Mantovani; Helen L Richards; Dónal G Fortune; Marie Cumberbatch; Rebecca J Dearman; Giorgio Terenghi; Ian Kimber; Christopher E M Griffiths
The effects of acute social stress on epidermal Langerhans' cell frequency and expression of cutaneous neuropeptides.
The Journal of investigative dermatology 2008;128(5):1273-9.
2008: Rebecca Jane Dearman; Lorna Beresford; Laura Bailey; Helen Theresa Caddick; Catherine Jean Betts; Ian Kimber
Di-(2-ethylhexyl) phthalate is without adjuvant effect in mice on ovalbumin.
Toxicology 2008;244(2-3):231-41.
2008: N Tsakiri; Ian Kimber; Nancy J Rothwell; Emmanuel Pinteaux
Interleukin-1-induced interleukin-6 synthesis is mediated by the neutral sphingomyelinase/Src kinase pathway in neurones.
British journal of pharmacology 2008;153(4):775-83.
2008: Niki Tsakiri; Ian Kimber; Nancy J Rothwell; Emmanuel Pinteaux
Mechanisms of interleukin-6 synthesis and release induced by interleukin-1 and cell depolarisation in neurones.
Molecular and cellular neurosciences 2008;37(1):110-8.
2007: Catherine J Betts; Rebecca J Dearman; Ian Kimber; Cindy A Ryan; G Frank Gerberick; Jon Lalko; Anne Marie Api
B220 analysis with the local lymph node assay: proposal for a more flexible prediction model.
Journal of applied toxicology : JAT 2007;27(5):506-10.
2007: David A Basketter; Frank Gerberick; Ian Kimber
The local lymph node assay and the assessment of relative potency: status of validation.
Contact dermatitis 2007;57(2):70-5.
2007: Grace Patlewicz; Aynur O Aptula; E Uriarte; David W Roberts; Petra S Kern; G Frank Gerberick; Ian Kimber; Rebecca J Dearman; Cindy A Ryan; David A Basketter
An evaluation of selected global (Q)SARs/expert systems for the prediction of skin sensitisation potential.
SAR and QSAR in environmental research 2007;18(5-6):515-41.
2007: David W Roberts; Grace Patlewicz; Petra S Kern; Frank Gerberick; Ian Kimber; Rebecca J Dearman; Cindy A Ryan; David A Basketter; Aynur O Aptula
Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization.
Chemical research in toxicology 2007;20(7):1019-30.
2007: Cindy A Ryan; Ian Kimber; David A Basketter; Marc Pallardy; Lucy A Gildea; G Frank Gerberick
Dendritic cells and skin sensitization: biological roles and uses in hazard identification.
Toxicology and applied pharmacology 2007;221(3):384-94.
2007: Costanza Rovida; David A Basketter; Silvia Casati; Odile de Silva; Helma Hermans; Ian Kimber; Irene Manou; Hans Ulrich Weltzien; Erwin Roggen
Management of an integrated project (Sens-it-iv) to develop in vitro tests to assess sensitisation.
Alternatives to laboratory animals : ATLA 2007;35(3):317-22.
2007: Ian Kimber; Raymond Agius; David A Basketter; Emanuela Corsini; Paul Cullinan; Rebecca J Dearman; Elena Gimenez-Arnau; Leona Greenwell; Thomas Hartung; Frieke Kuper; Piero Maestrelli; Erwin Roggen; Costanza Rovida
Chemical respiratory allergy: opportunities for hazard identification and characterisation. The report and recommendations of ECVAM workshop 60.
Alternatives to laboratory animals : ATLA 2007;35(2):243-65.
2007: Jonathan M L White; Anthony Teik-Jin Goon; Ian R Jowsey; David A Basketter; Rose K H Mak; Ian Kimber; John P McFadden
Oral tolerance to contact allergens: a common occurrence? A review.
Contact dermatitis 2007;56(5):247-54.
2007: Rebecca J Dearman; M J C Alcocer; Ian Kimber
Influence of plant lipids on immune responses in mice to the major Brazil nut allergen Ber e 1.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(4):582-91.
2007: David A Basketter; Camilla K Pease; Gerald Kasting; Ian Kimber; Silvia Casati; Mark Cronin; Walter Diembeck; Frank Gerberick; Jonathan Hadgraft; Thomas Hartung; Jean-Paul Marty; Efstathios Nikolaidis; Grace Patlewicz; David Roberts; Erwin Roggen; Costanza Rovida; Johannes J M van de Sandt
Skin sensitisation and epidermal disposition: the relevance of epidermal disposition for sensitisation hazard identification and risk assessment. The report and recommendations of ECVAM workshop 59.
Alternatives to laboratory animals : ATLA 2007;35(1):137-54.
2007: Catherine J Betts; L Beresford; Rebecca J Dearman; Jon Lalko; A P Api; Ian Kimber
The use of ethanol:diethylphthalate as a vehicle for the local lymph node assay.
Contact dermatitis 2007;56(2):70-5.
2007: Cindy A Ryan; Joel G Chaney; G Frank Gerberick; Petra S Kern; Rebecca J Dearman; Ian Kimber; David A Basketter
Extrapolating local lymph node assay EC3 values to estimate relative sensitizing potency.
Cutaneous and ocular toxicology 2007;26(2):135-45.
2007: David A Basketter; Ian Kimber
Information derived from sensitization test methods: test sensitivity, false positives and false negatives.
Contact dermatitis 2007;56(1):1-4.
2007: Rebecca J Dearman; Ian Kimber
A mouse model for food allergy using intraperitoneal sensitization.
Methods (San Diego, Calif.) 2007;41(1):91-8.
2006: Catherine J Betts; Rebecca J Dearman; Jon R Heylings; Ian Kimber; David A Basketter
Skin sensitization potency of methyl methacrylate in the local lymph node assay: comparisons with guinea-pig data and human experience.
Contact dermatitis 2006;55(3):140-7.
2006: Guy Mainwaring; Fei Ling Lim; Kate Antrobus; Cindy Swain; Mike Clapp; Ian Kimber; George Orphanides; Jonathan G Moggs
Identification of early molecular pathways affected by paraquat in rat lung.
Toxicology 2006;225(2-3):157-72.
2006: Lucy A Gildea; Cindy A Ryan; Leslie M Foertsch; Jennifer M Kennedy; Rebecca J Dearman; Ian Kimber; G Frank Gerberick
Identification of gene expression changes induced by chemical allergens in dendritic cells: opportunities for skin sensitization testing.
The Journal of investigative dermatology 2006;126(8):1813-22.
2006: Ruth Stuckey; Tom Aldridge; Fei Ling Lim; David Moore; Helen Tinwell; Nicola Doherty; Reginald Davies; Andrew G Smith; Ian Kimber; John Ashby; George Orphanides; Jonathan G Moggs
Induction of iron homeostasis genes during estrogen-induced uterine growth and differentiation.
Molecular and cellular endocrinology 2006;253(1-2):22-9.
2006: A Cockshott; P Evans; Cindy A Ryan; G Frank Gerberick; Catherine J Betts; Rebecca J Dearman; Ian Kimber; David A Basketter
The local lymph node assay in practice: a current regulatory perspective.
Human & experimental toxicology 2006;25(7):387-94.
2006: Ian R Jowsey; David A Basketter; Carl Westmoreland; Ian Kimber
A future approach to measuring relative skin sensitising potency: a proposal.
Journal of applied toxicology : JAT 2006;26(4):341-50.
2006: Marie Cumberbatch; Minal Singh; Rebecca J Dearman; Helen S Young; Ian Kimber; Christopher E M Griffiths
Impaired Langerhans cell migration in psoriasis.
The Journal of experimental medicine 2006;203(4):953-60.
2006: Ian Kimber; Rebecca J Dearman; Catherine J Betts; G Frank Gerberick; Cindy A Ryan; Petra S Kern; Grace Patlewicz; David A Basketter
The local lymph node assay and skin sensitization: a cut-down screen to reduce animal requirements?
Contact dermatitis 2006;54(4):181-5.
2006: Ralph Andre; Jonathan G Moggs; Ian Kimber; Nancy J Rothwell; Emmanuel Pinteaux
Gene regulation by IL-1beta independent of IL-1R1 in the mouse brain.
Glia 2006;53(5):477-83.
2005: G Frank Gerberick; Cindy A Ryan; Petra S Kern; Harald Schlatter; Rebecca J Dearman; Ian Kimber; Grace Patlewicz; David A Basketter
Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods.
Dermatitis : contact, atopic, occupational, drug : official journal of the American Contact Dermatitis Society, North American Contact Dermatitis Group 2005;16(4):157-202.
2005: Rebecca J Dearman; Ian Kimber
Characterisation of immune responses to food allergens in mice.
The Proceedings of the Nutrition Society 2005;64(4):426-33.
2005: Cindy A Ryan; G Frank Gerberick; Lucy A Gildea; Ben C Hulette; Catherine J Betts; Marie Cumberbatch; Rebecca J Dearman; Ian Kimber
Interactions of contact allergens with dendritic cells: opportunities and challenges for the development of novel approaches to hazard assessment.
Toxicological sciences : an official journal of the Society of Toxicology 2005;88(1):4-11.
2005: Christopher E M Griffiths; Rebecca J Dearman; Marie Cumberbatch; Ian Kimber
Cytokines and Langerhans cell mobilisation in mouse and man.
Cytokine 2005;32(2):67-70.
2005: Ralph Andre; Dominique Lerouet; Ian Kimber; Emmanuel Pinteaux; Nancy J Rothwell
Regulation of expression of the novel IL-1 receptor family members in the mouse brain.
Journal of neurochemistry 2005;95(2):324-30.
2005: Richard A Currie; Vincent Bombail; Jason D Oliver; David Moore; Fei Ling Lim; Victoria Gwilliam; Ian Kimber; Kevin Chipman; Jonathan G Moggs; George Orphanides
Gene ontology mapping as an unbiased method for identifying molecular pathways and processes affected by toxicant exposure: application to acute effects caused by the rodent non-genotoxic carcinogen diethylhexylphthalate.
Toxicological sciences : an official journal of the Society of Toxicology 2005;86(2):453-69.
2005: Marie Cumberbatch; Kirsty Clelland; Rebecca J Dearman; Ian Kimber
Impact of cutaneous IL-10 on resident epidermal Langerhans' cells and the development of polarized immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(1):43-50.
2005: Catherine J Betts; Rebecca J Dearman; Ian Kimber; Howard I Maibach
Potency and risk assessment of a skin-sensitizing disperse dye using the local lymph node assay.
Contact dermatitis 2005;52(5):268-72.
2005: Rebecca J Dearman; Neil E Humphreys; R A Skinner; Ian Kimber
Allergen-induced cytokine phenotypes in mice: role of CD4 and CD8 T cell populations.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(4):498-505.
2005: Jonathan G Moggs; T C Murphy; Fei Ling Lim; David Moore; Ruth Stuckey; K Antrobus; Ian Kimber; George Orphanides
Anti-proliferative effect of estrogen in breast cancer cells that re-express ERalpha is mediated by aberrant regulation of cell cycle genes.
Journal of molecular endocrinology 2005;34(2):535-51.
2005: Ian Kimber; Rebecca J Dearman
What makes a chemical a respiratory sensitizer?
Current opinion in allergy and clinical immunology 2005;5(2):119-24.
2005: Penglian Wang; Brenda Meinhardt; Ralph Andre; Blair R Renshaw; Ian Kimber; Nancy J Rothwell; Emmanuel Pinteaux
The interleukin-1-related cytokine IL-1F8 is expressed in glial cells, but fails to induce IL-1beta signalling responses.
Cytokine 2005;29(6):245-50.
2005: Ralph Andre; Emmanuel Pinteaux; Ian Kimber; Nancy J Rothwell
Differential actions of IL-1 alpha and IL-1 beta in glial cells share common IL-1 signalling pathways.
Neuroreport 2005;16(2):153-7.
2005: Silvia Casati; Pierre Aeby; David A Basketter; Andrea Cavani; Alessandra Gennari; G Frank Gerberick; Peter Griem; Thomas Hartung; Ian Kimber; Jean-Pierre Lepoittevin; B Jean Meade; Marc Pallardy; Nathalie Rougier; Francoise Rousset; Gilles Rubinstenn; Federica Sallusto; Geert R Verheyen; Valérie Zuang
Dendritic cells as a tool for the predictive identification of skin sensitisation hazard.
Alternatives to laboratory animals : ATLA 2005;33(1):47-62.
2005: Rebecca J Dearman; RA Skinner; N Deakin; D Shaw; Ian Kimber
Evaluation of an in vitro method for the measurement of specific IgE antibody responses: the rat basophilic leukemia (RBL) cell assay.
Toxicology 2005;206(2):195-205.
2004: Jonathan G Moggs; Helen Tinwell; Tracey Spurway; Hur-Song Chang; Ian Pate; Fei Ling Lim; David Moore; Anthony Soames; Ruth Stuckey; Richard Currie; Tong Zhu; Ian Kimber; John Ashby; George Orphanides
Phenotypic anchoring of gene expression changes during estrogen-induced uterine growth.
Environmental health perspectives 2004;112(16):1589-606.
2004: Catherine J Betts; Brian F Flanagan; Helen T Caddick; Rebecca J Dearman; Ian Kimber
Intradermal exposure of BALB/c strain mice to peanut protein elicits a type 2 cytokine response.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(10):1589-99.
2004: Jonathan G Moggs; John Ashby; Helen Tinwell; Fei Ling Lim; David Moore; Ian Kimber; George Orphanides
The need to decide if all estrogens are intrinsically similar.
Environmental health perspectives 2004;112(11):1137-42.
2004: Rebecca J Dearman; Monica Bhushan; Marie Cumberbatch; Ian Kimber; Christopher E M Griffiths
Measurement of cytokine expression and Langerhans cell migration in human skin following suction blister formation.
Experimental dermatology 2004;13(7):452-60.
2004: Cindy A Ryan; Lucy A Gildea; Ben C Hulette; Rebecca J Dearman; Ian Kimber; G Frank Gerberick
Gene expression changes in peripheral blood-derived dendritic cells following exposure to a contact allergen.
Toxicology letters 2004;150(3):301-16.
2004: G Frank Gerberick; Cindy A Ryan; Petra S Kern; Rebecca J Dearman; Ian Kimber; Grace Patlewicz; David A Basketter
A chemical dataset for evaluation of alternative approaches to skin-sensitization testing.
Contact dermatitis 2004;50(5):274-88.
2004: Ian Kimber; Marie Cumberbatch; Catherine J Betts; Rebecca J Dearman
Dendritic cells and skin sensitisation hazard assessment.
Toxicology in vitro : an international journal published in association with BIBRA 2004;18(2):195-202.
2004: Rebecca J Dearman; Ian Kimber
Local lymph node assays.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2004;Chapter 18():Unit18.2.
2003: Rebecca J Dearman; Ian Kimber
Factors influencing the induction phase of skin sensitization.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 2003;14(4):188-94.
2003: Ralph Andre; Rachel D Wheeler; Peter D Collins; Giamal N Luheshi; Stuart Pickering-Brown; Ian Kimber; Nancy J Rothwell; Emmanuel Pinteaux
Identification of a truncated IL-18R beta mRNA: a putative regulator of IL-18 expressed in rat brain.
Journal of neuroimmunology 2003;145(1-2):40-5.
2003: Ian Kimber; David A Basketter; M Butler; AO Gamer; JL Garrigue; G Frank Gerberick; C Newsome; W Steiling; Hans-Werner Vohr
Classification of contact allergens according to potency: proposals.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2003;41(12):1799-809.
2003: Rebecca J Dearman; S Stone; Helen T Caddick; David A Basketter; Ian Kimber
Evaluation of protein allergenic potential in mice: dose-response analyses.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(11):1586-94.
2003: Rebecca J Dearman; RA Skinner; Corinne HEROUET-GUICHENEY; K Labay; E Debruyne; Ian Kimber
Induction of IgE antibody responses by protein allergens: inter-laboratory comparisons.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2003;41(11):1509-16.
2003: George Orphanides; Ian Kimber
Toxicogenetics: applications and opportunities.
Toxicological sciences : an official journal of the Society of Toxicology 2003;75(1):1-6.
2003: Ian Kimber; Rebecca J Dearman; G Frank Gerberick; R Roggeband; David A Basketter
Designation of substances as skin sensitizing chemicals: a commentary.
Human & experimental toxicology 2003;22(8):439-43.
2003: E Vicky Warbrick; Joanne D Kilgour; Rebecca J Dearman; Ian Kimber; P H Dugard
Inhalation exposure to methylene chloride does not induce systemic immunotoxicity in rats.
Journal of toxicology and environmental health. Part A 2003;66(13):1207-19.
2003: Marie Cumberbatch; Rebecca J Dearman; Christopher E M Griffiths; Ian Kimber
Epidermal Langerhans cell migration and sensitisation to chemical allergens.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(7-8):797-804.
2003: Rebecca J Dearman; RA Skinner; Neil E Humphreys; Ian Kimber
Methods for the identification of chemical respiratory allergens in rodents: comparisons of cytokine profiling with induced changes in serum IgE.
Journal of applied toxicology : JAT 2003;23(4):199-207.
2003: Herve Boutin; Ian Kimber; Nancy J Rothwell; Emmanuel Pinteaux
The expanding interleukin-1 family and its receptors: do alternative IL-1 receptor/signaling pathways exist in the brain?
Molecular neurobiology 2003;27(3):239-48.
2003: Ian Kimber; Rebecca J Dearman; André H Penninks; Léon M J Knippels; Robert B Buchanan; Bruce Hammerberg; Hilary A Jackson; Ricki M Helm
Assessment of protein allergenicity on the basis of immune reactivity: animal models.
Environmental health perspectives 2003;111(8):1125-30.
2003: Ian Kimber; Rebecca J Dearman
What makes a chemical an allergen?
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2003;90(5 Suppl 2):28-31.
2003: Neil E Humphreys; Rebecca J Dearman; Ian Kimber
Assessment of cumulative allergen-activated lymph node cell proliferation using flow cytometry.
Toxicological sciences : an official journal of the Society of Toxicology 2003;73(1):80-9.
2003: Marie Cumberbatch; Monica Bhushan; Rebecca J Dearman; Ian Kimber; Christopher E M Griffiths
IL-1beta-induced Langerhans' cell migration and TNF-alpha production in human skin: regulation by lactoferrin.
Clinical and experimental immunology 2003;132(2):352-9.
2003: Ian Kimber; Catherine J Betts; Rebecca J Dearman
Assessment of the allergenic potential of proteins.
Toxicology letters 2003;140-141():297-302.
2003: Catherine J Betts; Jonathan G Moggs; Helen T Caddick; Marie Cumberbatch; George Orphanides; Rebecca J Dearman; Cindy A Ryan; Ben C Hulette; G Frank Gerberick; Ian Kimber
Assessment of glycosylation-dependent cell adhesion molecule 1 as a correlate of allergen-stimulated lymph node activation.
Toxicology 2003;185(1-2):103-17.
2003: Ian Kimber; Sue Stone; Rebecca J Dearman
Assessment of the inherent allergenic potential of proteins in mice.
Environmental health perspectives 2003;111(2):227-31.
2003: Rebecca J Dearman; Catherine J Betts; Neil E Humphreys; Brian F Flanagan; Nicola J Gilmour; David A Basketter; Ian Kimber
Chemical allergy: considerations for the practical application of cytokine profiling.
Toxicological sciences : an official journal of the Society of Toxicology 2003;71(2):137-45.
2002: Ian Kimber; Rebecca J Dearman
Chemical respiratory allergy: role of IgE antibody and relevance of route of exposure.
Toxicology 2002;181-182():311-5.
2002: Catherine J Betts; Rebecca J Dearman; Brian F Flanagan; Ian Kimber
Temporal changes in cytokine gene expression profiles induced in mice by trimellitic anhydride.
Toxicology letters 2002;136(2):121-32.
2002: Ian Kimber; Rebecca J Dearman; David A Basketter; Cindy A Ryan; G Frank Gerberick
The local lymph node assay: past, present and future.
Contact dermatitis 2002;47(6):315-28.
2002: Rebecca J Dearman; E Vicky Warbrick; R Skinner; Ian Kimber
Cytokine fingerprinting of chemical allergens: species comparisons and statistical analyses.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(12):1881-92.
2002: Ian Kimber; Rebecca J Dearman
Factors affecting the development of food allergy.
The Proceedings of the Nutrition Society 2002;61(4):435-9.
2002: Ian Kimber
Reduction, refinement and replacement: putting the immune system to work.
Alternatives to laboratory animals : ATLA 2002;30(6):569-77.
2002: Cindy A Ryan; Lynn W Cruse; R A Skinner; Rebecca J Dearman; Ian Kimber; G Frank Gerberick
Examination of a vehicle for use with water soluble materials in the murine local lymph node assay.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(11):1719-25.
2002: Rebecca J Dearman; Andrew Filby; Ian R Humphreys; Ian Kimber
Interleukins 5 and 13 characterize immune responses to respiratory sensitizing acid anhydrides.
Journal of applied toxicology : JAT 2002;22(5):317-25.
2002: G Frank Gerberick; Lynn W Cruse; Cindy A Ryan; Ben C Hulette; Joel G Chaney; Robert A Skinner; Rebecca J Dearman; Ian Kimber
Use of a B cell marker (B220) to discriminate between allergens and irritants in the local lymph node assay.
Toxicological sciences : an official journal of the Society of Toxicology 2002;68(2):420-8.
2002: Susan Hasmall; George Orphanides; Neil James; William D Pennie; Kathryn Hedley; Anthony Soames; Ian Kimber; Ruth Roberts
Downregulation of lactoferrin by PPARalpha ligands: role in perturbation of hepatocyte proliferation and apoptosis.
Toxicological sciences : an official journal of the Society of Toxicology 2002;68(2):304-13.
2002: Marie Cumberbatch; Rebecca J Dearman; Richard W Groves; Christos Antonopoulos; Ian Kimber
Differential regulation of epidermal langerhans cell migration by interleukins (IL)-1alpha and IL-1beta during irritant- and allergen-induced cutaneous immune responses.
Toxicology and applied pharmacology 2002;182(2):126-35.
2002: Ian Kimber; Rebecca J Dearman
Approaches to assessment of the allergenic potential of novel proteins in food from genetically modified crops.
Toxicological sciences : an official journal of the Society of Toxicology 2002;68(1):4-8.
2002: William D Pennie; Ian Kimber
Toxicogenomics; transcript profiling and potential application to chemical allergy.
Toxicology in vitro : an international journal published in association with BIBRA 2002;16(3):319-26.
2002: Keith T Atherton; Rebecca J Dearman; Ian Kimber
Protein allergenicity in mice: a potential approach for hazard identification.
Annals of the New York Academy of Sciences 2002;964():163-71.
2002: Rebecca J Dearman; Helen T Caddick; S Stone; J G Kenna; David A Basketter; Ian Kimber
Immunogenic properties of rapidly digested food proteins following gavage exposure of mice: a comparison of ovalbumin with a potato acid phosphatase preparation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(5):625-33.
2002: E Vicky Warbrick; Rebecca J Dearman; Ian Kimber
IgG and IgE antibody responses following exposure of Brown Norway rats to trimellitic anhydride: comparison of inhalation and topical exposure.
Toxicology 2002;172(3):157-68.
2002: Marie Cumberbatch; Rebecca J Dearman; Ian Kimber
Influence of ageing on Langerhans cell migration in mice: identification of a putative deficiency of epidermal interleukin-1beta.
Immunology 2002;105(4):466-77.
2002: Clifford R Elcombe; Jenny Odum; John R Foster; Susan Stone; Susan Hasmall; Anthony Soames; Ian Kimber; John Ashby
Prediction of rodent nongenotoxic carcinogenesis: evaluation of biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens.
Environmental health perspectives 2002;110(4):363-75.
2002: Ian Kimber; Rebecca J Dearman
Immunologic basis for autoimmunity and the potential influences of xenobiotics.
Toxicology letters 2002;127(1-3):77-81.
2002: Ian Kimber; David A Basketter; G Frank Gerberick; Rebecca J Dearman
Allergic contact dermatitis.
International immunopharmacology 2002;2(2-3):201-11.
2002: Ian Kimber; Rebecca J Dearman
Allergic contact dermatitis: the cellular effectors.
Contact dermatitis 2002;46(1):1-5.
2002: Ian Kimber; Marie Cumberbatch; Rebecca J Dearman; DR Headon; Monica Bhushan; Christopher E M Griffiths
Lactoferrin: influences on Langerhans cells, epidermal cytokines, and cutaneous inflammation.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2002;80(1):103-7.
2002: Ian Kimber; Rebecca J Dearman
Immune responses: adverse versus non-adverse effects.
Toxicologic pathology 2002;30(1):54-8.
2002: Monica Bhushan; Marie Cumberbatch; Rebecca J Dearman; S M Andrew; Ian Kimber; Christopher E M Griffiths
Tumour necrosis factor-alpha-induced migration of human Langerhans cells: the influence of ageing.
The British journal of dermatology 2002;146(1):32-40.
2002: E Vicky Warbrick; Rebecca J Dearman; Ian Kimber
Induced changes in total serum IgE concentration in the Brown Norway rat: potential for identification of chemical respiratory allergens.
Journal of applied toxicology : JAT 2002;22(1):1-11.
2001: Rebecca J Dearman; Helen T Caddick; S Stone; David A Basketter; Ian Kimber
Characterization of antibody responses induced in rodents by exposure to food proteins: influence of route of exposure.
Toxicology 2001;167(3):217-31.
2001: Ian Kimber; David A Basketter; R Roggeband
Chemical respiratory allergy: classification and labelling.
Toxicology 2001;167(2):159-62.
2001: MW Craighead; K M Middlehurst; Rosalind LeFeuvre; Ian Kimber; Nancy J Rothwell
Oxidised adenosine 5'-triphosphate, a P2X(7) antagonist, is toxic to rat cerebellar granule neurones in vitro.
Neuroscience letters 2001;311(2):77-80.
2001: G F Gerberick; Michael K Robinson; Cindy A Ryan; Rebecca J Dearman; Ian Kimber; David A Basketter; ZM Wright; J G Marks
Contact allergenic potency: correlation of human and local lymph node assay data.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 2001;12(3):156-61.
2001: Ian Kimber; JS Pichowski; Catherine J Betts; Marie Cumberbatch; David A Basketter; Rebecca J Dearman
Alternative approaches to the identification and characterization of chemical allergens.
Toxicology in vitro : an international journal published in association with BIBRA 2001;15(4-5):307-12.
2001: David A Basketter; ZM Wright; EV Warbrick; Rebecca J Dearman; Ian Kimber; Cindy A Ryan; G Frank Gerberick; I R White
Human potency predictions for aldehydes using the local lymph node assay.
Contact dermatitis 2001;45(2):89-94.
2001: David A Basketter; G Frank Gerberick; Ian Kimber
Measurement of allergenic potency using the local lymph node assay.
Trends in pharmacological sciences 2001;22(6):264-5.
2001: Rebecca J Dearman; ZM Wright; David A Basketter; Cindy A Ryan; G Frank Gerberick; Ian Kimber
The suitability of hexyl cinnamic aldehyde as a calibrant for the murine local lymph node assay.
Contact dermatitis 2001;44(6):357-61.
2001: David A Basketter; G Frank Gerberick; Ian Kimber
Skin sensitisation, vehicle effects and the local lymph node assay.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2001;39(6):621-7.
2001: E Vicky Warbrick; Rebecca J Dearman; John Ashby; P Schmezer; Ian Kimber
Preliminary assessment of the skin sensitizing activity of selected rodent carcinogens using the local lymph node assay.
Toxicology 2001;163(1):63-9.
2001: ZM Wright; P A Basketter; L Blaikie; K J Cooper; EV Warbrick; Rebecca J Dearman; Ian Kimber
Vehicle effects on skin sensitizing potency of four chemicals: assessment using the local lymph node assay.
International journal of cosmetic science 2001;23(2):75-83.
2001: Christopher E M Griffiths; Marie Cumberbatch; S C Tucker; Rebecca J Dearman; S Andrew; DR Headon; Ian Kimber
Exogenous topical lactoferrin inhibits allergen-induced Langerhans cell migration and cutaneous inflammation in humans.
The British journal of dermatology 2001;144(4):715-25.
2001: W Steiling; David A Basketter; K Berthold; M Butler; JL Garrigue; Ian Kimber; L Lea; C Newsome; R Roggeband; G Stropp; S Waterman; C Wiemann
Skin sensitisation testing--new perspectives and recommendations.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2001;39(4):293-301.
2001: Rebecca J Dearman; Ian Kimber
Determination of protein allergenicity: studies in mice.
Toxicology letters 2001;120(1-3):181-6.
2001: Ian Kimber; Rebecca J Dearman
Food allergy: what are the issues?
Toxicology letters 2001;120(1-3):165-70.
2001: Christos Antonopoulos; Marie Cumberbatch; Rebecca J Dearman; R J Daniel; Ian Kimber; Richard W Groves
Functional caspase-1 is required for Langerhans cell migration and optimal contact sensitization in mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(6):3672-7.
2001: Marie Cumberbatch; Rebecca J Dearman; Christos Antonopoulos; Richard W Groves; Ian Kimber
Interleukin (IL)-18 induces Langerhans cell migration by a tumour necrosis factor-alpha- and IL-1beta-dependent mechanism.
Immunology 2001;102(3):323-30.
2001: Rebecca J Dearman; Ian Kimber
Cytokine fingerprinting and hazard assessment of chemical respiratory allergy.
Journal of applied toxicology : JAT 2001;21(2):153-63.
2001: JS Pichowski; Marie Cumberbatch; Rebecca J Dearman; David A Basketter; Ian Kimber
Allergen-induced changes in interleukin 1 beta (IL-1 beta) mRNA expression by human blood-derived dendritic cells: inter-individual differences and relevance for sensitization testing.
Journal of applied toxicology : JAT 2001;21(2):115-21.
2001: Ian Kimber
The local lymph node assay and potential application to the identification of drug allergens.
Toxicology 2001;158(1-2):59-64.
2001: Ian Kimber; David A Basketter; K Berthold; M Butler; JL Garrigue; L Lea; C Newsome; R Roggeband; W Steiling; G Stropp; S Waterman; C Wiemann
Skin sensitization testing in potency and risk assessment.
Toxicological sciences : an official journal of the Society of Toxicology 2001;59(2):198-208.
2001: Marie Cumberbatch; Rebecca J Dearman; Ian Kimber
In vivo assays of langerhans cell migration.
Methods in molecular medicine 2001;64():331-46.
2001: EV Warbrick; Rebecca J Dearman; Ian Kimber
Prediction of drug allergenicity: possible use of the local lymph node assay.
Current opinion in drug discovery & development 2001;4(1):60-5.
2000: Rebecca J Dearman; Ian Kimber
Role of CD4(+) T helper 2-type cells in cutaneous inflammatory responses induced by fluorescein isothiocyanate.
Immunology 2000;101(4):442-51.
2000: MW Craighead; Herve Boutin; K M Middlehurst; Stuart M Allan; N Brooks; Ian Kimber; Nancy J Rothwell
Influence of corticotrophin releasing factor on neuronal cell death in vitro and in vivo.
Brain research 2000;881(2):139-43.
2000: John Ashby; Helen Tinwell; Jenny Odum; Ian Kimber; AN Brooks; Ian Pate; C C Boyle
Diet and the aetiology of temporal advances in human and rodent sexual development.
Journal of applied toxicology : JAT 2000;20(5):343-7.
2000: Cindy A Ryan; G Frank Gerberick; Lynn W Cruse; David A Basketter; LJ Lea; L Blaikie; Rebecca J Dearman; EV Warbrick; Ian Kimber
Activity of human contact allergens in the murine local lymph node assay.
Contact dermatitis 2000;43(2):95-102.
2000: JS Pichowski; Marie Cumberbatch; David A Basketter; Ian Kimber
Investigation of induced changes in interleukin 1beta mRNA expression by cultured human dendritic cells as an in vitro approach to skin sensitization testing.
Toxicology in vitro : an international journal published in association with BIBRA 2000;14(4):351-60.
2000: Marie Cumberbatch; Rebecca J Dearman; Christopher E M Griffiths; Ian Kimber
Langerhans cell migration.
Clinical and experimental dermatology 2000;25(5):413-8.
2000: Marie Cumberbatch; Rebecca J Dearman; Sonia Uribe-Luna; DR Headon; Pauline P Ward; Orla M Conneely; Ian Kimber
Regulation of epidermal Langerhans cell migration by lactoferrin.
Immunology 2000;100(1):21-8.
2000: Rebecca J Dearman; EV Warbrick; I R Humphreys; Ian Kimber
Characterization in mice of the immunological properties of five allergenic acid anhydrides.
Journal of applied toxicology : JAT 2000;20(3):221-30.
2000: EV Warbrick; Rebecca J Dearman; David A Basketter; Ian Kimber
Failure of vehicle to influence local lymph node assay response to benzocaine.
Contact dermatitis 2000;42(3):164-5.
2000: G F Gerberick; Cindy A Ryan; Ian Kimber; Rebecca J Dearman; LJ Lea; David A Basketter
Local lymph node assay: validation assessment for regulatory purposes.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 2000;11(1):3-18.
2000: PR Holden; NH James; AN Brooks; Ruth A Roberts; Ian Kimber; William D Pennie
Identification of a possible association between carbon tetrachloride-induced hepatotoxicity and interleukin-8 expression.
Journal of biochemical and molecular toxicology 2000;14(5):283-90.
1999: David A Basketter; LJ Lea; K Cooper; J Stocks; Andrea Dickens; I Pate; Rebecca J Dearman; Ian Kimber
Threshold for classification as a skin sensitizer in the local lymph node assay: a statistical evaluation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1999;37(12):1167-74.
1999: LJ Lea; EV Warbrick; Rebecca J Dearman; Ian Kimber; David A Basketter
The impact of vehicle on assessment of relative skin sensitization potency of 1,4-dihydroquinone in the local lymph node assay.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 1999;10(4):213-8.
1999: David A Basketter; LJ Lea; K J Cooper; Cindy A Ryan; G F Gerberick; Rebecca J Dearman; Ian Kimber
Identification of metal allergens in the local lymph node assay.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 1999;10(4):207-12.
1999: Marie Cumberbatch; Christopher E M Griffiths; S C Tucker; Rebecca J Dearman; Ian Kimber
Tumour necrosis factor-alpha induces Langerhans cell migration in humans.
The British journal of dermatology 1999;141(2):192-200.
1999: David A Basketter; LJ Lea; Andrea Dickens; D Briggs; I Pate; Rebecca J Dearman; Ian Kimber
A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses.
Journal of applied toxicology : JAT 1999;19(4):261-6.
1999: EV Warbrick; Rebecca J Dearman; LJ Lea; David A Basketter; Ian Kimber
Local lymph node assay responses to paraphenylenediamine: intra- and inter-laboratory evaluations.
Journal of applied toxicology : JAT 1999;19(4):255-60.
1999: Marie Cumberbatch; Rebecca J Dearman; Ian Kimber
Langerhans cell migration in mice requires intact type I interleukin 1 receptor (IL-1RI) function.
Archives of dermatological research 1999;291(6):357-61.
1999: Ian Kimber; J S Pichowski; D A Basketter; Rebecca J Dearman
Immune responses to contact allergens: novel approaches to hazard evaluation.
Toxicology letters 1999;106(2-3):237-46.
1999: Ian Kimber; G F Gerberick; David A Basketter
Thresholds in contact sensitization: theoretical and practical considerations.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1999;37(5):553-60.
1999: Rebecca J Dearman; J Hilton; David A Basketter; Ian Kimber
Cytokine endpoints for the local lymph node assay: consideration of interferon-gamma and interleukin 12.
Journal of applied toxicology : JAT 1999;19(3):149-55.
1999: Marie Cumberbatch; Rebecca J Dearman; Ian Kimber
Inhibition by dexamethasone of Langerhans cell migration: influence of epidermal cytokine signals.
Immunopharmacology 1999;41(3):235-43.
1999: Ian Kimber; Nancy Kerkvliet; S L Taylor; J D Astwood; K Sarlo; Rebecca J Dearman
Toxicology of protein allergenicity: prediction and characterization.
Toxicological sciences : an official journal of the Society of Toxicology 1999;48(2):157-62.
1999: David A Basketter; R Rodford; Ian Kimber; I Smith; J E Wahlberg
Skin sensitization risk assessment: a comparative evaluation of 3 isothiazolinone biocides.
Contact dermatitis 1999;40(3):150-4.
1999: EV Warbrick; Rebecca J Dearman; David A Basketter; Ian Kimber
Analysis of interleukin 12 protein production and mRNA expression in mice exposed topically to chemical allergens.
Toxicology 1999;132(1):57-66.
1999: Rebecca J Dearman; David A Basketter; P Evans; Ian Kimber
Comparison of cytokine secretion profiles provoked in mice by glutaraldehyde and formaldehyde.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29(1):124-32.
1998: Ian Kimber
Allergy, asthma and the environment: an introduction.
Toxicology letters 1998;102-103():301-6.
1998: Marie Cumberbatch; Rebecca J Dearman; Ian Kimber
Characteristics and regulation of the expression on interleukin 1 receptors by murine Langerhans cells and keratinocytes.
Archives of dermatological research 1998;290(12):688-95.
1998: Ian Kimber; EV Warbrick; Rebecca J Dearman
Chemical respiratory allergy, IgE and the relevance of predictive test methods: a commentary.
Human & experimental toxicology 1998;17(10):537-40.
1998: Rebecca J Dearman; J Hilton; P Evans; P Harvey; David A Basketter; Ian Kimber
Temporal stability of local lymph node assay responses to hexyl cinnamic aldehyde.
Journal of applied toxicology : JAT 1998;18(4):281-4.
1998: EV Warbrick; Rebecca J Dearman; David A Basketter; G Frank Gerberick; Cindy A Ryan; Ian Kimber
Analysis of cytokine mRNA expression following repeated exposure of mice to chemical contact and respiratory allergens.
Journal of applied toxicology : JAT 1998;18(3):205-13.
1998: Ian Kimber; J Hilton; Rebecca J Dearman; G Frank Gerberick; Cindy A Ryan; David A Basketter; LJ Lea; R V House; Gregory S Ladics; Scott E Loveless; Kenneth L Hastings
Assessment of the skin sensitization potential of topical medicaments using the local lymph node assay: an interlaboratory evaluation.
Journal of toxicology and environmental health. Part A 1998;53(7):563-79.
1998: Rebecca J Dearman; David A Basketter; Ian Kimber
Selective induction of type 2 cytokines following topical exposure of mice to platinum salts.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1998;36(3):199-207.
1998: J Hilton; Rebecca J Dearman; P Harvey; P Evans; David A Basketter; Ian Kimber
Estimation of relative skin sensitizing potency using the local lymph node assay: a comparison of formaldehyde with glutaraldehyde.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 1998;9(1):29-33.
1998: Ian Kimber; Marie Cumberbatch; Rebecca J Dearman; P Ward; DR Headon; Orla M Conneely
Regulation by lactoferrin of epidermal Langerhans cell migration.
Advances in experimental medicine and biology 1998;443():251-5.
1998: Ian Kimber
Regulatory immunotoxicology--the scientist's point of view: an introduction.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1998;20():271-4.
1997: J Hilton; Rebecca J Dearman; N Sattar; David A Basketter; Ian Kimber
Characteristics of antibody responses induced in mice by protein allergens.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1997;35(12):1209-18.
1997: Marie Cumberbatch; Rebecca J Dearman; Ian Kimber
Langerhans cells require signals from both tumour necrosis factor-alpha and interleukin-1 beta for migration.
Immunology 1997;92(3):388-95.
1997: Ian Kimber; C E Lumley; D D Metcalfe
Allergenicity of proteins.
Human & experimental toxicology 1997;16(9):516-8.
1997: M R Holliday; E Corsini; S Smith; David A Basketter; Rebecca J Dearman; Ian Kimber
Differential induction of cutaneous TNF-alpha and IL-6 by topically applied chemicals.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 1997;8(3):158-64.
1997: Marie Cumberbatch; Rebecca J Dearman; Ian Kimber
Interleukin 1 beta and the stimulation of Langerhans cell migration: comparisons with tumour necrosis factor alpha.
Archives of dermatological research 1997;289(5):277-84.
1997: Rebecca J Dearman; Marie Cumberbatch; J Hilton; I Fielding; David A Basketter; Ian Kimber
A re-appraisal of the skin-sensitizing activity of 2,4-dinitrothiocyanobenzene.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1997;35(2):261-9.
1997: Ian Kimber; Rebecca J Dearman
Cell and molecular biology of chemical allergy.
Clinical reviews in allergy & immunology 1997;15(2):145-68.
1997: Marie Cumberbatch; Rebecca J Dearman; Ian Kimber
Langerhans cells require signals from both tumour necrosis factor alpha and interleukin 1 beta for migration.
Advances in experimental medicine and biology 1997;417():125-8.
1997: Marie Cumberbatch; Rebecca J Dearman; Ian Kimber
Stimulation of Langerhans cell migration in mice by tumour necrosis factor alpha and interleukin 1 beta.
Advances in experimental medicine and biology 1997;417():121-4.
1997: Ian Kimber; Rebecca J Dearman; Marie Cumberbatch
Epidermal cytokines and the induction of allergic and non-allergic contact dermatitis.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1997;19():229-38.
1997: Rebecca J Dearman; S Smith; David A Basketter; Ian Kimber
Classification of chemical allergens according to cytokine secretion profiles of murine lymph node cells.
Journal of applied toxicology : JAT 1997;17(1):53-62.
1996: Rebecca J Dearman; A Moussavi; D M Kemeny; Ian Kimber
Contribution of CD4+ and CD8+ T lymphocyte subsets to the cytokine secretion patterns induced in mice during sensitization to contact and respiratory chemical allergens.
Immunology 1996;89(4):502-10.
1996: Marie Cumberbatch; Rebecca J Dearman; Ian Kimber
Adhesion molecule expression by epidermal Langerhans cells and lymph node dendritic cells: a comparison.
Archives of dermatological research 1996;288(12):739-44.
1996: David A Basketter; G Frank Gerberick; Ian Kimber; Scott E Loveless
The local lymph node assay: a viable alternative to currently accepted skin sensitization tests.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1996;34(10):985-97.
1996: K L Vento; Rebecca J Dearman; Ian Kimber; D A Basketter; John W Coleman
Selectivity of IgE responses, mast cell sensitization, and cytokine expression in the immune response of Brown Norway rats to chemical allergens.
Cellular immunology 1996;172(2):246-53.
1996: David A Basketter; Ian Kimber
Olive oil: suitability for use as a vehicle in the local lymph node assay.
Contact dermatitis 1996;35(3):190-1.
1996: I Hilton; Rebecca J Dearman; I Fielding; David A Basketter; Ian Kimber
Evaluation of the sensitizing potential of eugenol and isoeugenol in mice and guinea pigs.
Journal of applied toxicology : JAT 1996;16(5):459-64.
1996: Rebecca J Dearman; Marie Cumberbatch; J Hilton; H M Clowes; I Fielding; J R Heylings; Ian Kimber
Influence of dibutyl phthalate on dermal sensitization to fluorescein isothiocyanate.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1996;33(1):24-30.
1996: Ian Kimber; I L Bernstein; M H Karol; Michael K Robinson; Kathy Sarlo; M K Selgrade
Workshop overview. Identification of respiratory allergens.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1996;33(1):1-10.
1996: Ian Kimber
The role of the skin in the development of chemical respiratory hypersensitivity.
Toxicology letters 1996;86(2-3):89-92.
1996: Ian Kimber; J Hilton; David A Basketter; Rebecca J Dearman
Predictive testing for respiratory sensitization in the mouse.
Toxicology letters 1996;86(2-3):193-8.
1996: J Hilton; Rebecca J Dearman; David A Basketter; E W Scholes; Ian Kimber
Experimental assessment of the sensitizing properties of formaldehyde.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1996;34(6):571-8.
1996: Rebecca J Dearman; David A Basketter; Ian Kimber
Characterization of chemical allergens as a function of divergent cytokine secretion profiles induced in mice.
Toxicology and applied pharmacology 1996;138(2):308-16.
1996: J R Heylings; H M Clowes; Marie Cumberbatch; Rebecca J Dearman; I Fielding; J Hilton; Ian Kimber
Sensitization to 2,4-dinitrochlorobenzene: influence of vehicle on absorption and lymph node activation.
Toxicology 1996;109(1):57-65.
1996: Scott E Loveless; Gregory S Ladics; G Frank Gerberick; Cindy A Ryan; David A Basketter; E W Scholes; R V House; J Hilton; Rebecca J Dearman; Ian Kimber
Further evaluation of the local lymph node assay in the final phase of an international collaborative trial.
Toxicology 1996;108(1-2):141-52.
1996: Rebecca J Dearman; J C Hope; S J Hopkins; Ian Kimber
Antigen-induced unresponsiveness in contact sensitivity: association of depressed T lymphocyte proliferative responses with decreased interleukin 6 secretion.
Immunology letters 1996;50(1-2):29-34.
1996: Marie Cumberbatch; Rebecca J Dearman; Ian Kimber
Constitutive and inducible expression of interleukin-6 by Langerhans cells and lymph node dendritic cells.
Immunology 1996;87(4):513-8.
1996: J Hilton; Rebecca J Dearman; M S Boylett; I Fielding; David A Basketter; Ian Kimber
The mouse IgE test for the identification of potential chemical respiratory allergens: considerations of stability and controls.
Journal of applied toxicology : JAT 1996;16(2):165-70.
1996: M R Holliday; Rebecca J Dearman; David A Basketter; Ian Kimber
Stimulation by oxazolone of increased IL-6, but not IL-10, in the skin of mice.
Toxicology 1996;106(1-3):237-42.
1996: M R Holliday; Rebecca J Dearman; E Corsini; David A Basketter; Ian Kimber
Selective stimulation of cutaneous interleukin 6 expression by skin allergens.
Journal of applied toxicology : JAT 1996;16(1):65-70.
1996: David A Basketter; E W Scholes; I Fielding; Rebecca J Dearman; J Hilton; Ian Kimber
Dichloronitrobenzene: a reappraisal of its skin sensitization potential.
Contact dermatitis 1996;34(1):55-8.
1996: Ian Kimber
Impact of environmental pollution on respiratory sensitization and asthma.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1996;18():34-48.
1995: J Ashby; David A Basketter; D Paton; Ian Kimber
Structure activity relationships in skin sensitization using the murine local lymph node assay.
Toxicology 1995;103(3):177-94.
1995: Ian Kimber; M R Holliday; Rebecca J Dearman
Cytokine regulation of chemical sensitization.
Toxicology letters 1995;82-83():491-6.
1995: Rebecca J Dearman; David A Basketter; Ian Kimber
Differential cytokine production following chronic exposure of mice to chemical respiratory and contact allergens.
Immunology 1995;86(4):545-50.
1995: Ian Kimber; J Hilton; Rebecca J Dearman; G Frank Gerberick; Cindy A Ryan; David A Basketter; E W Scholes; Gregory S Ladics; Scott E Loveless; R V House
An international evaluation of the murine local lymph node assay and comparison of modified procedures.
Toxicology 1995;103(1):63-73.
1995: J C Hope; Marie Cumberbatch; I Fielding; Rebecca J Dearman; Ian Kimber; S J Hopkins
Identification of dendritic cells as a major source of interleukin-6 in draining lymph nodes following skin sensitization of mice.
Immunology 1995;86(3):441-7.
1995: Ian Kimber; M F Wilks
Chemical respiratory allergy. Toxicological and occupational health issues.
Human & experimental toxicology 1995;14(9):735-6.
1995: John Ashby; J Hilton; Rebecca J Dearman; Ian Kimber
Streptozotocin: inherent but not expressed skin sensitizing activity.
Contact dermatitis 1995;33(3):165-7.
1995: Marie Cumberbatch; J C Hope; Rebecca J Dearman; S J Hopkins; Ian Kimber
Migration of interleukin-6 producing Langerhans cells to draining lymph nodes following skin sensitization.
Advances in experimental medicine and biology 1995;378():531-3.
1995: Marie Cumberbatch; I Fielding; Ian Kimber
Epidermal Langerhans cell migration: signals and mechanisms.
Advances in experimental medicine and biology 1995;378():173-5.
1995: Marie Cumberbatch; Ian Kimber
Tumour necrosis factor-alpha is required for accumulation of dendritic cells in draining lymph nodes and for optimal contact sensitization.
Immunology 1995;84(1):31-5.
1995: Ian Kimber
Biomarkers of immunotoxicity in man.
Human & experimental toxicology 1995;14(1):148-9.
1994: Ian Kimber
Chemical allergy: Cellular and molecular mechanisms and novel approaches to predictive testing.
Toxicology in vitro : an international journal published in association with BIBRA 1994;8(5):987-90.
1994: J C Hope; Rebecca J Dearman; Ian Kimber; S J Hopkins
The kinetics of cytokine production by draining lymph node cells following primary exposure of mice to chemical allergens.
Immunology 1994;83(2):250-5.
1994: Ian Kimber; Rebecca J Dearman; E W Scholes; David A Basketter
The local lymph node assay: developments and applications.
Toxicology 1994;93(1):13-31.
1994: Ian Kimber
Cytokines and regulation of allergic sensitization to chemicals.
Toxicology 1994;93(1):1-11.
1994: J Hilton; Rebecca J Dearman; R J Debicki; L S Ramdin; Ian Kimber
Interleukin 6 production in vitro: An alternative read-out for the local lymph node assay.
Toxicology in vitro : an international journal published in association with BIBRA 1994;8(4):711-3.
1994: Marie Cumberbatch; Ian Kimber
Epidermal cytokines and skin sensitization hazard.
Toxicology in vitro : an international journal published in association with BIBRA 1994;8(4):685-7.
1994: Rebecca J Dearman; E W Scholes; L S Ramdin; David A Basketter; Ian Kimber
The local lymph node assay: an interlaboratory evaluation of interleukin 6 (IL-6) production by draining lymph node cells.
Journal of applied toxicology : JAT 1994;14(4):287-91.
1994: J Hilton; Rebecca J Dearman; David A Basketter; Ian Kimber
Serological responses induced in mice by immunogenic proteins and by protein respiratory allergens.
Toxicology letters 1994;73(1):43-53.
1994: David A Basketter; E W Scholes; Ian Kimber
The performance of the local lymph node assay with chemicals identified as contact allergens in the human maximization test.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1994;32(6):543-7.
1994: M R Holliday; E M Banks; Rebecca J Dearman; Ian Kimber; John W Coleman
Interactions of IFN-gamma with IL-3 and IL-4 in the regulation of serotonin and arachidonate release from mouse peritoneal mast cells.
Immunology 1994;82(1):70-4.
1994: Rebecca J Dearman; L S Ramdin; David A Basketter; Ian Kimber
Inducible interleukin-4-secreting cells provoked in mice during chemical sensitization.
Immunology 1994;81(4):551-7.
1994: John W Coleman; M R Holliday; Rebecca J Dearman; Ian Kimber
Cytokine-mast cell interactions: relevance to IgE-mediated chemical allergy.
Toxicology 1994;88(1-3):225-35.
1994: N J Rattray; P A Botham; P M Hext; D R Woodcock; I Fielding; Rebecca J Dearman; Ian Kimber
Induction of respiratory hypersensitivity to diphenylmethane-4,4'-diisocyanate (MDI) in guinea pigs. Influence of route of exposure.
Toxicology 1994;88(1-3):15-30.
1994: Marie Cumberbatch; I Fielding; Ian Kimber
Modulation of epidermal Langerhans' cell frequency by tumour necrosis factor-alpha.
Immunology 1994;81(3):395-401.
1994: J C Hope; Rebecca J Dearman; R J Debicki; Ian Kimber; S J Hopkins
Interleukin-6 production by draining lymph node cells following primary contact sensitisation of mice: relationship to the proliferative response.
International archives of allergy and immunology 1994;103(4):378-83.
1993: R W Lewis; J C McCall; P A Botham; Ian Kimber
Investigation of TNF-alpha release as a measure of skin irritancy.
Toxicology in vitro : an international journal published in association with BIBRA 1993;7(4):393-5.
1993: Ian Kimber
Epidermal cytokines in contact hypersensitivity: Immunological roles and practical applications.
Toxicology in vitro : an international journal published in association with BIBRA 1993;7(4):295-8.
1993: John Ashby; J Hilton; R J Dearman; R D Callander; Ian Kimber
Mechanistic relationship among mutagenicity, skin sensitization, and skin carcinogenicity.
Environmental health perspectives 1993;101(1):62-7.
1993: M R Holliday; John W Coleman; Rebecca J Dearman; Ian Kimber
Induction of mast cell sensitization by chemical allergens: a comparative study.
Journal of applied toxicology : JAT 1993;13(2):137-42.
1993: M R Holliday; Rebecca J Dearman; Ian Kimber; John W Coleman
Sensitization of mice to chemical allergens modulates the responsiveness of isolated mast cells to IgE-dependent activation.
Immunology 1993;78(3):508-10.
1993: M Cumberbatch; R C Scott; David A Basketter; E W Scholes; J Hilton; Rebecca J Dearman; Ian Kimber
Influence of sodium lauryl sulphate on 2,4-dinitrochlorobenzene-induced lymph node activation.
Toxicology 1993;77(1-2):181-91.
1993: John W Coleman; M R Holliday; Ian Kimber; Krisztina Maria Zsebo; S J Galli
Regulation of mouse peritoneal mast cell secretory function by stem cell factor, IL-3 or IL-4.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(2):556-62.
1993: David A Basketter; E Selbie; E W Scholes; D Lees; Ian Kimber; P A Botham
Results with OECD recommended positive control sensitizers in the maximization, Buehler and local lymph node assays.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1993;31(1):63-7.
1992: Ian Kimber; R J Dearman
The mechanisms and evaluation of chemically induced allergy.
Toxicology letters 1992;64-65 Spec No():79-84.
1992: Ian Kimber; M Cumberbatch
Dendritic cells and cutaneous immune responses to chemical allergens.
Toxicology and applied pharmacology 1992;117(2):137-46.
1992: Ian Kimber; M Cumberbatch
Stimulation of Langerhans cell migration by tumor necrosis factor alpha (TNF-alpha).
The Journal of investigative dermatology 1992;99(5):48S-50S.
1992: M Cumberbatch; S J Gould; S W Peters; David A Basketter; Rebecca J Dearman; Ian Kimber
Langerhans cells, antigen presentation, and the diversity of responses to chemical allergens.
The Journal of investigative dermatology 1992;99(5):107S-108S.
1992: Ian Kimber; G Frank Gerberick; H Van Loveren; R V House
Chemical allergy: molecular mechanisms and practical applications.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1992;19(4):479-83.
1992: David A Basketter; E W Scholes; M Cumberbatch; C D Evans; Ian Kimber
Sulphanilic acid: divergent results in the guinea pig maximization test and the local lymph node assay.
Contact dermatitis 1992;27(4):209-13.
1992: R J Dearman; D A Basketter; Ian Kimber
Variable effects of chemical allergens on serum IgE concentration in mice. Preliminary evaluation of a novel approach to the identification of respiratory sensitizers.
Journal of applied toxicology : JAT 1992;12(5):317-23.
1992: Rebecca J Dearman; David A Basketter; J W Coleman; Ian Kimber
The cellular and molecular basis for divergent allergic responses to chemicals.
Chemico-biological interactions 1992;84(1):1-10.
1992: E W Scholes; David A Basketter; A E Sarll; Ian Kimber; C D Evans; K Miller; M C Robbins; Paul Harrison; S J Waite
The local lymph node assay: results of a final inter-laboratory validation under field conditions.
Journal of applied toxicology : JAT 1992;12(3):217-22.
1992: M Cumberbatch; S W Peters; S J Gould; Ian Kimber
Intercellular adhesion molecule-1 (ICAM-1) expression by lymph node dendritic cells: comparison with epidermal Langerhans cells.
Immunology letters 1992;32(2):105-10.
1992: Rebecca J Dearman; Ian Kimber
Divergent immune responses to respiratory and contact chemical allergens: antibody elicited by phthalic anhydride and oxazolone.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1992;22(2):241-50.
1992: Ian Kimber; D A Basketter
The murine local lymph node assay: a commentary on collaborative studies and new directions.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1992;30(2):165-9.
1992: M Cumberbatch; Ian Kimber
Dermal tumour necrosis factor-alpha induces dendritic cell migration to draining lymph nodes, and possibly provides one stimulus for Langerhans' cell migration.
Immunology 1992;75(2):257-63.
1992: R J Dearman; L M Spence; Ian Kimber
Characterization of murine immune responses to allergenic diisocyanates.
Toxicology and applied pharmacology 1992;112(2):190-7.
1992: R J Dearman; J A Mitchell; D A Basketter; Ian Kimber
Differential ability of occupational chemical contact and respiratory allergens to cause immediate and delayed dermal hypersensitivity reactions in mice.
International archives of allergy and immunology 1992;97(4):315-21.
1992: M Cumberbatch; S J Gould; S W Peters; David A Basketter; Rebecca J Dearman; Ian Kimber
Influence of topical exposure to chemical allergens on murine Langerhans cells. Comparison of 2,4-dinitrochlorobenzene with trimellitic anhydride.
Journal of clinical & laboratory immunology 1992;37(2):65-81.
1991: M Cumberbatch; S J Gould; S W Peters; Ian Kimber
MHC class II expression by Langerhans' cells and lymph node dendritic cells: possible evidence for maturation of Langerhans' cells following contact sensitization.
Immunology 1991;74(3):414-9.
1991: Ian Kimber
Toxicology and the immune system: a perspective.
Human & experimental toxicology 1991;10(6):445-9.
1991: M Cumberbatch; I Illingworth; Ian Kimber
Antigen-bearing dendritic cells in the draining lymph nodes of contact sensitized mice: cluster formation with lymphocytes.
Immunology 1991;74(1):139-45.
1991: Ian Kimber; C Weisenberger
Anamnestic responses to contact allergens: application in the murine local lymph node assay.
Journal of applied toxicology : JAT 1991;11(2):129-33.
1991: Rebecca J Dearman; Ian Kimber
Differential stimulation of immune function by respiratory and contact chemical allergens.
Immunology 1991;72(4):563-70.
1991: Ian Kimber; S Quirke; M Cumberbatch; John Ashby; D Paton; R D Aldridge; J A Hunter; M H Beck
Lymphocyte transformation and thiuram sensitization.
Contact dermatitis 1991;24(3):164-71.
1991: Ian Kimber; Rebecca J Dearman
Investigation of lymph node cell proliferation as a possible immunological correlate of contact sensitizing potential.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1991;29(2):125-9.
1991: Ian Kimber; J Hilton; P A Botham; David A Basketter; E W Scholes; K Miller; M C Robbins; Paul Harrison; T J Gray; S J Waite
The murine local lymph node assay: results of an inter-laboratory trial.
Toxicology letters 1991;55(2):203-13.
1991: R J Dearman; Ian Kimber
Immunotoxicology and allergy: Opportunities for in vitro analysis.
Toxicology in vitro : an international journal published in association with BIBRA 1991;5(5-6):519-24.
1991: Ian Kimber; J R Foster; D Baker; J L Turk
Selective impairment of T lymphocyte activation following contact sensitization with oxazolone.
International archives of allergy and applied immunology 1991;95(2-3):142-8.
1991: Rebecca J Dearman; J M Hegarty; Ian Kimber
Inhalation exposure of mice to trimellitic anhydride induces both IgG and IgE anti-hapten antibody.
International archives of allergy and applied immunology 1991;95(1):70-6.
1990: S J Hopkins; M Humphreys; A Kinnaird; D A Jones; Ian Kimber
Production of interleukin-1 by draining lymph node cells during the induction phase of contact sensitization in mice.
Immunology 1990;71(4):493-6.
1990: Ian Kimber; S Hill; J A Mitchell; S W Peters; S C Knight
Antigenic competition in contact sensitivity. Evidence for changes in dendritic cell migration and antigen handling.
Immunology 1990;71(2):271-6.
1990: Ian Kimber; J Hilton; P A Botham
Identification of contact allergens using the murine local lymph node assay: comparisons with the Buehler occluded patch test in guinea pigs.
Journal of applied toxicology : JAT 1990;10(3):173-80.
1990: Ian Kimber; M Cumberbatch; A N Bentley; D Baker
Requirements for antigenic competition in contact sensitivity.
Journal of clinical & laboratory immunology 1990;32(2):67-72.
1990: John Ashby; J E Gallagher; M Kohan; Helen Tinwell; Ian Kimber; D Paton; R D Callander; I Chouroulinkov
1-Chloromethylpyrene: a reference skin sensitizer and genotoxin.
Mutation research 1990;243(4):281-9.
1990: Ian Kimber; S Quirke; M H Beck
Attempts to identify the causative allergen in cases of allergic contact dermatitis using an in vitro lymphocyte transformation test.
Toxicology in vitro : an international journal published in association with BIBRA 1990;4(4-5):302-6.
1990: Ian Kimber; M Cumberbatch; M Humphreys; S J Hopkins
Contact hypersensitivity induces plasma interleukin 6.
International archives of allergy and applied immunology 1990;92(1):97-9.
1990: Ian Kimber; A Kinnaird; S W Peters; J A Mitchell
Correlation between lymphocyte proliferative responses and dendritic cell migration in regional lymph nodes following skin painting with contact-sensitizing agents.
International archives of allergy and applied immunology 1990;93(1):47-53.
1990: Ian Kimber; A N Bentley; R K Ward; D Baker; J L Turk
Antigen-restricted antigenic competition induced by 2,4-dinitrochlorobenzene: association with depression of lymphocyte proliferation.
International archives of allergy and applied immunology 1990;91(3):315-22.
1989: Ian Kimber
Aspects of the immune response to contact allergens: opportunities for the development and modification of predictive test methods.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1989;27(11):755-62.
1989: A Kinnaird; S W Peters; J R Foster; Ian Kimber
Dendritic cell accumulation in draining lymph nodes during the induction phase of contact allergy in mice.
International archives of allergy and applied immunology 1989;89(2-3):202-10.
1989: Ian Kimber; R K Ward; C J Shepherd; M N Smith; K P McAdam; J G Raynes
Acute-phase proteins and the serological evaluation of experimental contact sensitivity in the mouse.
International archives of allergy and applied immunology 1989;89(2-3):149-55.
1986: Ian Kimber; P A Botham; N J Rattray; S T Walsh
Contact-sensitizing and tolerogenic properties of 2,4-dinitrothiocyanobenzene.
International archives of allergy and applied immunology 1986;81(3):258-64.