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William Baird

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Andrew Larkin; Lisbeth K Siddens; Susan C Tilton; Katrina M Waters; David E Williams; Sharon K Krueger; William M Baird
Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin.
Lyndsey E Shorey; Lisbeth K Siddens; Katrina M Waters; William M Baird; David J Castro; Richard A Corley; Christiane V Löhr; Melissa M Matzke; David E Williams
Transplacental carcinogenesis with dibenzo[def,p]chrysene (DBC): timing of maternal exposures determines target tissue response in offspring.
George S Bailey; Ashok Reddy; Clifford B Pereira; U Harttig; William M Baird; Jan M Spitsbergen; Jerry D Hendricks; Gayle A Orner; David E Williams; James A Swenberg
Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study.

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All Publications

2013: Andrew Larkin; Lisbeth K Siddens; Susan C Tilton; Katrina M Waters; David E Williams; Sharon K Krueger; William M Baird
Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin.
Toxicology and applied pharmacology 2013;267(2):192-9.
2012: Lyndsey E Shorey; Lisbeth K Siddens; Katrina M Waters; William M Baird; David J Castro; Richard A Corley; Christiane V Löhr; Melissa M Matzke; David E Williams
Transplacental carcinogenesis with dibenzo[def,p]chrysene (DBC): timing of maternal exposures determines target tissue response in offspring.
Cancer letters 2012;317(1):49-55.
2009: George S Bailey; Ashok Reddy; Clifford B Pereira; U Harttig; William M Baird; Jan M Spitsbergen; Jerry D Hendricks; Gayle A Orner; David E Williams; James A Swenberg
Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study.
Chemical research in toxicology 2009;22(7):1264-76.
2008: Louisa A Hooven; William M Baird
Proteomic analysis of MCF-7 cells treated with benzo[a]pyrene, dibenzo[a,l]pyrene, coal tar extract, and diesel exhaust extract.
Toxicology 2008;249(1):1-10.
2008: David J Castro; William M Baird; Clifford B Pereira; Jack Giovanini; Christiane V Löhr; Kay A Fischer; Zhen Yu; Frank J Gonzalez; Sharon K Krueger; David E Williams
Fetal mouse Cyp1b1 and transplacental carcinogenesis from maternal exposure to dibenzo(a,l)pyrene.
Cancer prevention research (Philadelphia, Pa.) 2008;1(2):128-34.
2008: Lauren A Courter; Andreas Luch; Tamara Musafia-Jeknic; Volker M Arlt; Kay Fischer; Robert J Bildfell; Cliff Pereira; David H Phillips; Miriam C Poirier; William M Baird
The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo.
Cancer letters 2008;265(1):135-47.
2007: Lauren A Courter; Cliff Pereira; William M Baird
Diesel exhaust influences carcinogenic PAH-induced genotoxicity and gene expression in human breast epithelial cells in culture.
Mutation research 2007;625(1-2):72-82.
2007: Suyeal Bae; Heduck Mah; Surendrakumar Chaturvedi; Tamara Musafia Jeknic; William M Baird; Amy K Katz; HL Carrell; Jenny P Glusker; Takao Okazaki; Kenneth K Laali; Barbara Zajc; Mahesh K Lakshman
Synthetic, crystallographic, computational, and biological studies of 1,4-difluorobenzo[c]phenanthrene and its metabolites.
The Journal of organic chemistry 2007;72(20):7625-33.
2007: Brinda Mahadevan; Charis P Marston; Andreas Luch; Wan-Mohaiza Dashwood; Eric Brooks; Cliff Pereira; Johannes Doehmer; William M Baird
Competitive inhibition of carcinogen-activating CYP1A1 and CYP1B1 enzymes by a standardized complex mixture of PAH extracted from coal tar.
International journal of cancer. Journal international du cancer 2007;120(6):1161-8.
2007: Brinda Mahadevan; Andreas Luch; Jennifer Atkin; Melanie Haynes; Tuan Nguyen; William M Baird
Inhibition of human cytochrome p450 1b1 further clarifies its role in the activation of dibenzo[a,l]pyrene in cells in culture.
Journal of biochemical and molecular toxicology 2007;21(3):101-9.
2007: Lauren A Courter; Tamara Musafia-Jeknic; Kay Fischer; Robert J Bildfell; Jack Giovanini; Cliff Pereira; William M Baird
Urban dust particulate matter alters PAH-induced carcinogenesis by inhibition of CYP1A1 and CYP1B1.
Toxicological sciences : an official journal of the Society of Toxicology 2007;95(1):63-73.
2006: Brinda Mahadevan; Andreas Luch; Jennifer Atkin; Tuan Nguyen; Arun K Sharma; Shantu Amin; William M Baird
Investigation of the genotoxicity of dibenzo[c,p]chrysene in human carcinoma MCF-7 cells in culture.
Chemico-biological interactions 2006;164(3):181-91.
2006: Cristobal L Miranda; Woon-Gye Chung; Jun-Lan Wang-Buhler; Tamara Musafia-Jeknic; William M Baird; Donald R Buhler
Comparative in vitro metabolism of benzo[a]pyrene by recombinant zebrafish CYP1A and liver microsomes from beta-naphthoflavone-treated rainbow trout.
Aquatic toxicology (Amsterdam, Netherlands) 2006;80(2):101-8.
2006: Zhen Yu; Brinda Mahadevan; Christiane V Löhr; Kay A Fischer; Mandy A Louderback; Sharon K Krueger; Clifford B Pereira; Daniel J Albershardt; William M Baird; George S Bailey; David E Williams
Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by the polycyclic aromatic hydrocarbon dibenzo[a,l]pyrene.
Carcinogenesis 2006;27(10):2116-23.
2006: Brinda Mahadevan; Vikram Arora; Laura J Schild; Channa Keshava; Melissa L Cate; Patrick L Iversen; Miriam C Poirier; Ainsley Weston; Cliff Pereira; William M Baird
Reduction in tamoxifen-induced CYP3A2 expression and DNA adducts using antisense technology.
Molecular carcinogenesis 2006;45(2):118-25.
2005: Tamara Musafia-Jeknic; Brinda Mahadevan; Cliff Pereira; William M Baird
Long-term effects of a standardized complex mixture of urban dust particulate on the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons in human cells in culture.
Toxicological sciences : an official journal of the Society of Toxicology 2005;88(2):358-66.
2005: Brinda Mahadevan; Andreas Luch; Claudia F Bravo; Jennifer Atkin; Linda B Steppan; Cliff Pereira; Nancy Kerkvliet; William M Baird
Dibenzo[a,l]pyrene induced DNA adduct formation in lung tissue in vivo.
Cancer letters 2005;227(1):25-32.
2005: Louisa A Hooven; Brinda Mahadevan; Channa Keshava; Christopher Johns; Cliff Pereira; Dhimant Desai; Shantu Amin; Ainsley Weston; William M Baird
Effects of suberoylanilide hydroxamic acid and trichostatin A on induction of cytochrome P450 enzymes and benzo[a]pyrene DNA adduct formation in human cells.
Bioorganic & medicinal chemistry letters 2005;15(5):1283-7.
2005: Ramune Reliene; Alexandra Hlavacova; Brinda Mahadevan; William M Baird; Robert H Schiestl
Diesel exhaust particles cause increased levels of DNA deletions after transplacental exposure in mice.
Mutation research 2005;570(2):245-52.
2005: William M Baird; Louisa A Hooven; Brinda Mahadevan
Carcinogenic polycyclic aromatic hydrocarbon-DNA adducts and mechanism of action.
Environmental and molecular mutagenesis 2005;45(2-3):106-14.
2005: Brinda Mahadevan; Channa Keshava; Tamara Musafia-Jeknic; Arta Pecaj; Ainsley Weston; William M Baird
Altered gene expression patterns in MCF-7 cells induced by the urban dust particulate complex mixture standard reference material 1649a.
Cancer research 2005;65(4):1251-8.
2005: Brinda Mahadevan; Charis P Marston; Wan-Mohaiza Dashwood; Yonghai Li; Cliff Pereira; William M Baird
Effect of a standardized complex mixture derived from coal tar on the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons in human cells in culture.
Chemical research in toxicology 2005;18(2):224-31.
2004: William M Baird; Brinda Mahadevan
The uses of carcinogen-DNA adduct measurement in establishing mechanisms of mutagenesis and in chemoprevention.
Mutation research 2004;547(1-2):1-4.
2004: Brinda Mahadevan; Heather Parsons; Tamara Musafia; Arun K Sharma; Shantu Amin; Cliff Pereira; William M Baird
Effect of artificial mixtures of environmental polycyclic aromatic hydrocarbons present in coal tar, urban dust, and diesel exhaust particulates on MCF-7 cells in culture.
Environmental and molecular mutagenesis 2004;44(2):99-107.
2003: Takao Okazaki; Kenneth K Laali; Barbara Zajc; Mahesh K Lakshman; Subodh Kumar; William M Baird; Wan-Mohaiza Dashwood
Stable ion study of benzo[a]pyrene (BaP) derivatives: 7,8-dihydro-BaP, 9,10-dihydro-BaP and its 6-halo derivatives, 1- and 3-methoxy-9,10-dihydro-BaP-7(8H)-one, as well as the proximate carcinogen BaP 7,8-dihydrodiol and its dibenzoate, combined with a comparative DNA binding study of regioisomeric (1-, 4-, 2-) pyrenylcarbinols.
Organic & biomolecular chemistry 2003;1(9):1509-16.
2003: Brinda Mahadevan; Wan-Mohaiza Dashwood; Andreas Luch; Arta Pecaj; Johannes Doehmer; Albrecht Seidel; Cliff Pereira; William M Baird
Mutations induced by (-)-anti-11R,12S-dihydrodiol 13S,14R-epoxide of dibenzo[a,l]pyrene in the coding region of the hypoxanthine phosphoribosyltransferase (Hprt) gene in Chinese hamster V79 cells.
Environmental and molecular mutagenesis 2003;41(2):131-9.
2002: Jeroen Buters; Brinda Mahadevan; Leticia Quintanilla-Martinez; Frank J Gonzalez; Helmut Greim; William M Baird; Andreas Luch
Cytochrome P450 1B1 determines susceptibility to dibenzo[a,l]pyrene-induced tumor formation.
Chemical research in toxicology 2002;15(9):1127-35.
2001: Charis P Marston; Cliff Pereira; J Ferguson; K Fischer; Olaf R Hedstrom; Wan-Mohaiza Dashwood; William M Baird
Effect of a complex environmental mixture from coal tar containing polycyclic aromatic hydrocarbons (PAH) on the tumor initiation, PAH-DNA binding and metabolic activation of carcinogenic PAH in mouse epidermis.
Carcinogenesis 2001;22(7):1077-86.
2001: Brinda Mahadevan; Andreas Luch; Albrecht Seidel; J C Pelling; William M Baird
Effects of the (-)-anti-11R,12S-dihydrodiol 13S,14R-epoxide of dibenzo.
Carcinogenesis 2001;22(1):161-9.
2000: T L Weimer; Ashok Reddy; U Harttig; D Alexander; S C Stamm; MR Miller; William M Baird; Jerry D Hendricks; George Bailey
Influence of beta-naphthoflavone on 7,12-dimethylbenz(a)anthracene metabolism, DNA adduction, and tumorigenicity in rainbow trout.
Toxicological sciences : an official journal of the Society of Toxicology 2000;57(2):217-28.
2000: SM Heidel; Peter S MacWilliams; William M Baird; Wan-Mohaiza Dashwood; Jeroen Buters; F J Gonzalez; Michele Campaigne Larsen; Charles J Czuprynski; Colin R Jefcoate
Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene.
Cancer research 2000;60(13):3454-60.
2000: VJ Melendez-Colon; Andreas Luch; Albrecht Seidel; William M Baird
Formation of stable DNA adducts and apurinic sites upon metabolic activation of bay and fjord region polycyclic aromatic hydrocarbons in human cell cultures.
Chemical research in toxicology 2000;13(1):10-7.
1999: Ashok Reddy; U Harttig; M C Barth; William M Baird; Michael I Schimerlik; Jerry D Hendricks; George S Bailey
Inhibition of dibenzo[a,l]pyrene-induced multi-organ carcinogenesis by dietary chlorophyllin in rainbow trout.
Carcinogenesis 1999;20(10):1919-26.
1999: VJ Melendez-Colon; Andreas Luch; Albrecht Seidel; William M Baird
Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites.
Carcinogenesis 1999;20(10):1885-91.
1999: Andreas Luch; S Kishiyama; Albrecht Seidel; Johannes Doehmer; Helmut Greim; William M Baird
The K-region trans-8,9-diol does not significantly contribute as an intermediate in the metabolic activation of dibenzo[a,l]pyrene to DNA-binding metabolites by human cytochrome P450 1A1 or 1B1.
Cancer research 1999;59(18):4603-9.
1999: Johannes Doehmer; Jeroen Buters; Andreas Luch; Volker J Soballa; William M Baird; Hilary G Morrison; J J Stegeman; Alan J Townsend; William F Greenlee; H R Glatt; Albrecht Seidel; Jürgen Jacob; Helmut Greim
Molecular studies on the toxifying effects by genetically engineered cytochromes P450.
Drug metabolism reviews 1999;31(2):423-35.
1999: Andreas Luch; K Kudla; Albrecht Seidel; Johannes Doehmer; Helmut Greim; William M Baird
The level of DNA modification by (+)-syn-(11S,12R,13S,14R)- and (-)-anti-(11R,12S,13S,14R)-dihydrodiol epoxides of dibenzo[a,l]pyrene determined the effect on the proteins p53 and p21WAF1 in the human mammary carcinoma cell line MCF-7.
Carcinogenesis 1999;20(5):859-65.
1999: R Agarwal; Stephanie L Coffing; William M Baird; Ronald G Harvey; Anthony Dipple
Metabolic activation of 4H-cyclopenta[def]chrysene in human mammary carcinoma MCF-7 cell cultures.
Chemical research in toxicology 1999;12(5):437-41.
1999: VJ Melendez-Colon; Andreas Luch; Albrecht Seidel; William M Baird
Comparison of cytochrome P450- and peroxidase-dependent metabolic activation of the potent carcinogen dibenzo[a,l]pyrene in human cell lines: formation of stable DNA adducts and absence of a detectable increase in apurinic sites.
Cancer research 1999;59(7):1412-6.
1998: Andreas Luch; Stephanie L Coffing; Y M Tang; A Schneider; Volker J Soballa; Helmut Greim; Colin R Jefcoate; Albrecht Seidel; William F Greenlee; William M Baird; Johannes Doehmer
Stable expression of human cytochrome P450 1B1 in V79 Chinese hamster cells and metabolically catalyzed DNA adduct formation of dibenzo[a,l]pyrene.
Chemical research in toxicology 1998;11(6):686-95.
1997: VJ Melendez-Colon; C A Smith; Albrecht Seidel; Andreas Luch; Karl L Platt; William M Baird
Formation of stable adducts and absence of depurinating DNA adducts in cells and DNA treated with the potent carcinogen dibenzo[a,l]pyrene or its diol epoxides.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13542-7.
1997: S L Ralston; Stephanie L Coffing; Albrecht Seidel; Andreas Luch; Karl L Platt; William M Baird
Stereoselective activation of dibenzo[a,l]pyrene and its trans-11,12-dihydrodiol to fjord region 11,12-diol 13,14-epoxides in a human mammary carcinoma MCF-7 cell-mediated V79 cell mutation assay.
Chemical research in toxicology 1997;10(6):687-93.
1997: H J Einolf; W T Story; Craig B Marcus; Michele Campaigne Larsen; Colin R Jefcoate; William F Greenlee; H Yagi; D M Jerina; S Amin; S S Park; H V Gelboin; William M Baird
Role of cytochrome P450 enzyme induction in the metabolic activation of benzo[c]phenanthrene in human cell lines and mouse epidermis.
Chemical research in toxicology 1997;10(5):609-17.
1997: R Agarwal; Stephanie L Coffing; William M Baird; A S Kiselyov; Ronald G Harvey; Anthony Dipple
Metabolic activation of benzo[g]chrysene in the human mammary carcinoma cell line MCF-7.
Cancer research 1997;57(3):415-9.
1996: H J Einolf; S Amin; H Yagi; D M Jerina; William M Baird
Benzo[c]phenanthrene is activated to DNA-binding diol epoxides in the human mammary carcinoma cell line MCF-7 but only limited activation occurs in mouse skin.
Carcinogenesis 1996;17(10):2237-44.
1995: S L Ralston; Albrecht Seidel; Andreas Luch; Karl L Platt; William M Baird
Stereoselective activation of dibenzo[a,l]pyrene to (-)-anti (11R,12S,13S,14R)- and (+)-syn(11S,12R,13S,14R)-11,12-diol-13,14-epoxides which bind extensively to deoxyadenosine residues of DNA in the human mammary carcinoma cell line MCF-7.
Carcinogenesis 1995;16(12):2899-907.
1995: H H Lau; Stephanie L Coffing; H Lee; Ronald G Harvey; William M Baird
Stereoselectivity of activation of 7,12-dimethylbenz[a]anthracene- 3,4-dihydrodiol to the anti-diol epoxide metabolite in a human mammary carcinoma MCF-7 cell-mediated V79 cell mutation assay.
Chemical research in toxicology 1995;8(7):970-8.
1995: G W Boyd; MM Coombs; William M Baird
The presence of a trifluoromethyl rather than a methyl substituent in the bay-region greatly decreases the DNA-binding and tumour-initiating activity of the cyclopenta[alpha]phenanthren-17-ones.
Carcinogenesis 1995;16(10):2543-7.
1995: R J Polzer; Stephanie L Coffing; Craig B Marcus; S S Park; H V Gelboin; William M Baird
Inhibition of benzo[a]pyrene metabolism by insulin, FITC-insulin and an FITC-insulin-antibody conjugate in the human hepatoma cell line HepG2.
Chemico-biological interactions 1995;97(3):307-18.
1995: R J Mauthe; V M Cook; Stephanie L Coffing; William M Baird
Exposure of mammalian cell cultures to benzo[a]pyrene and light results in oxidative DNA damage as measured by 8-hydroxydeoxyguanosine formation.
Carcinogenesis 1995;16(1):133-7.
1994: H H Lau; William M Baird
Separation and characterization of post-labeled DNA adducts of stereoisomers of benzo[a]pyrene-7,8-diol-9,10-epoxide by immobilized boronate chromatography and HPLC analysis.
Carcinogenesis 1994;15(5):907-15.
1994: S L Ralston; H H Lau; Albrecht Seidel; Andreas Luch; Karl L Platt; William M Baird
The potent carcinogen dibenzo[a,l]pyrene is metabolically activated to fjord-region 11,12-diol 13,14-epoxides in human mammary carcinoma MCF-7 cell cultures.
Cancer research 1994;54(4):887-90.
1994: J J Schwartz; H H Lau; William M Baird
Base sequence selectivity in the binding of 7(R),8(S)-dihydroxy-9(S),10(R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene to oligodeoxyribonucleotide duplexes.
Chemical research in toxicology 1994;7(1):29-40.
1993: William M Baird; H H Lau; I Schmerold; Stephanie L Coffing; S L Brozich; H Lee; Ronald G Harvey
Analysis of polycyclic aromatic hydrocarbon-DNA adducts by postlabelling with the weak beta-emitters 35S-phosphorothioate and 33P-phosphate, immobilized boronate chromatography and high-performance liquid chromatography.
IARC scientific publications 1993;(124):217-26.
1992: Y Teffera; William M Baird; D L Smith
Detection of benzo[a]pyrene sulfate and glucuronide conjugates in cell culture medium by directly coupled microbore high-performance liquid chromatography-fast atom bombardment mass spectrometry.
Journal of chromatography 1992;577(1):69-76.
1992: E R Butch; H H Lau; K L Shaw; T A Smolarek; I Schmerold; John N Anderson; William M Baird; H Yagi; D M Jerina
High selectivity of polyclonal antibodies against DNA modified by diastereomeric benzo[c]phenanthrene-3,4-diol-1,2-epoxides.
Carcinogenesis 1992;13(5):895-9.
1992: H H Lau; William M Baird
The co-carcinogen benzo[e]pyrene increases the binding of a low dose of the carcinogen benzo[a]pyrene to DNA in Sencar mouse epidermis.
Cancer letters 1992;63(3):229-36.
1992: Y H Chae; D K Ho; John M Cassady; V M Cook; Craig B Marcus; William M Baird
Effects of synthetic and naturally occurring flavonoids on metabolic activation of benzo[a]pyrene in hamster embryo cell cultures.
Chemico-biological interactions 1992;82(2):181-93.
1992: Y L Liu; D K Ho; John M Cassady; V M Cook; William M Baird
Isolation of potential cancer chemopreventive agents from Eriodictyon californicum.
Journal of natural products 1992;55(3):357-63.
1992: J Eberhart; Stephanie L Coffing; John N Anderson; Craig B Marcus; T J Kalogeris; William M Baird; S S Park; H V Gelboin
The time-dependent increase in the binding of benzo[a]pyrene to DNA through (+)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide in primary rat hepatocyte cultures results from induction of cytochrome P450IA1 by benzo[a]pyrene treatment.
Carcinogenesis 1992;13(2):297-301.
1991: Y H Chae; Stephanie L Coffing; V M Cook; D K Ho; John M Cassady; William M Baird
Effects of biochanin A on metabolism, DNA binding and mutagenicity of benzo[a]pyrene in mammalian cell cultures.
Carcinogenesis 1991;12(11):2001-6.
1991: Y H Chae; Craig B Marcus; D K Ho; John M Cassady; William M Baird
Effects of synthetic and naturally occurring flavonoids on benzo[a]pyrene metabolism by hepatic microsomes prepared from rats treated with cytochrome P-450 inducers.
Cancer letters 1991;60(1):15-24.
1991: H H Lau; William M Baird
Detection and identification of benzo[a]pyrene-DNA adducts by [35S]phosphorothioate labeling and HPLC.
Carcinogenesis 1991;12(5):885-93.
1991: Y Teffera; William M Baird; D L Smith
Determination of benzo[a]pyrene sulfate conjugates from benzo[a]pyrene-treated cells by continuous-flow fast atom bombardment mass spectrometry.
Analytical chemistry 1991;63(5):453-6.
1990: John M Cassady; William M Baird; C J Chang
Natural products as a source of potential cancer chemotherapeutic and chemopreventive agents.
Journal of natural products 1990;53(1):23-41.
1988: John M Cassady; T M Zennie; Y H Chae; M A Ferin; N E Portuondo; William M Baird
Use of a mammalian cell culture benzo(a)pyrene metabolism assay for the detection of potential anticarcinogens from natural products: inhibition of metabolism by biochanin A, an isoflavone from Trifolium pratense L.
Cancer research 1988;48(22):6257-61.
1988: D Pruess-Schwartz; R J Mauthe; William M Baird
Instability of (+/-)-7 beta,8 alpha-dihydroxy-9 beta,10 beta-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (syn-BaPDE)-DNA adducts formed in benzo[a]pyrene-treated Wistar rat embryo cell cultures.
Carcinogenesis 1988;9(10):1863-8.
1988: W B Emary; Z G Shen; R G Cooks; I Plakunov; William M Baird
Nucleophilic reactions between biological conjugates and tetraalkylammonium ion pair reagents during desorption chemical ionization.
Biomedical & environmental mass spectrometry 1988;15(10):571-6.
1988: William M Baird; T M Zennie; M Ferin; Y H Chae; J Hatchell; John M Cassady
Glucolimnanthin, a plant glucosinolate, increases the metabolism and DNA binding of benzo[a]pyrene in hamster embryo cell cultures.
Carcinogenesis 1988;9(4):657-60.
1987: M A Morse; William M Baird; Gary P Carlson
Effects of sex and age on DMBA:DNA binding in epidermis of SENCAR mice following topical administration of dimethylbenz[a] anthracene.
Cancer letters 1987;37(1):25-31.
1987: T A Smolarek; S L Morgan; C G Moynihan; H Lee; Ronald G Harvey; William M Baird
Metabolism and DNA adduct formation of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in fish cell lines in culture.
Carcinogenesis 1987;8(10):1501-9.
1987: C J Moore; D Pruess-Schwartz; R J Mauthe; M N Gould; William M Baird
Interspecies differences in the major DNA adducts formed from benzo(a)pyrene but not 7,12-dimethylbenz(a)anthracene in rat and human mammary cell cultures.
Cancer research 1987;47(16):4402-6.
1987: D Pruess-Schwartz; William M Baird; H Yagi; D M Jerina; M A Pigott; Anthony Dipple
Stereochemical specificity in the metabolic activation of benzo(c)phenanthrene to metabolites that covalently bind to DNA in rodent embryo cell cultures.
Cancer research 1987;47(15):4032-7.
1987: T A Smolarek; William M Baird; E P Fisher; J DiGiovanni
Benzo(e)pyrene-induced alterations in the binding of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene to DNA in Sencar mouse epidermis.
Cancer research 1987;47(14):3701-6.
1987: I Plakunov; T A Smolarek; D L Fischer; J C Wiley; William M Baird
Separation by ion-pair high-performance liquid chromatography of the glucuronide, sulfate and glutathione conjugates formed from benzo[a]pyrene in cell cultures from rodents, fish and humans.
Carcinogenesis 1987;8(1):59-66.
1987: T A Smolarek; S L Morgan; J Kelley; William M Baird
Effects of pretreatment with benzo[a]pyrene on the stereochemical selectivity of metabolic activation of benzo[a]pyrene to DNA-binding metabolites in hamster embryo cell cultures.
Chemico-biological interactions 1987;64(1-2):71-82.
1986: D Pruess-Schwartz; William M Baird; A Nikbakht; B Alex Merrick; James K Selkirk
Benzo(a)pyrene:DNA adduct formation in normal human mammary epithelial cell cultures and the human mammary carcinoma T47D cell line.
Cancer research 1986;46(6):2697-702.
1986: T A Smolarek; C G Moynihan; C P Salmon; William M Baird
Benz[a]anthracene-induced alterations in the metabolic activation of benzo[a]pyrene by hamster embryo cell cultures.
Cancer letters 1986;30(3):243-9.
1986: T A Smolarek; William M Baird
Benzo(e)pyrene-induced alterations in the stereoselectivity of activation of 7,12-dimethylbenz(a)anthracene to DNA-binding metabolites in hamster embryo cell cultures.
Cancer research 1986;46(3):1170-5.
1986: D Pruess-Schwartz; William M Baird
Benzo(a)pyrene:DNA adduct formation in early-passage Wistar rat embryo cell cultures: evidence for multiple pathways of activation of benzo(a)pyrene.
Cancer research 1986;46(2):545-52.
1986: D M Jerina; J M Sayer; S K Agarwal; H Yagi; W Levin; A W Wood; A H Conney; D Pruess-Schwartz; William M Baird; M A Pigott
Reactivity and tumorigenicity of bay-region diol epoxides derived from polycyclic aromatic hydrocarbons.
Advances in experimental medicine and biology 1986;197():11-30.
1985: S M Sebti; T A Smolarek; C P Salmon; William M Baird
7,12-Dimethylbenz[a]anthracene-DNA adduct formation in Wistar rat and Syrian hamster embryo cell cultures.
Chemico-biological interactions 1985;56(1):1-12.
1985: S M Sebti; C G Moynihan; John N Anderson; William M Baird
Benzo[a]pyrene-DNA adduct formation in target and activator cells in a Wistar rat embryo cell-mediated V79 cell mutation assay.
Carcinogenesis 1985;6(7):983-8.
1985: D J Ashworth; William M Baird; CJ Chang; J D Ciupek; K L Busch; R G Cooks
Chemical modification of nucleic acids. Methylation of calf thymus DNA investigated by mass spectrometry and liquid chromatography.
Biomedical mass spectrometry 1985;12(7):309-18.
1985: S M Sebti; D Pruess-Schwartz; William M Baird
Species- and length of exposure-dependent differences in the benzo(a)pyrene:DNA adducts formed in embryo cell cultures from mice, rats, and hamsters.
Cancer research 1985;45(4):1594-600.
1984: D Pruess-Schwartz; S M Sebti; P T Gilham; William M Baird
Analysis of benzo(a)pyrene:DNA adducts formed in cells in culture by immobilized boronate chromatography.
Cancer research 1984;44(9):4104-10.
1984: T A Smolarek; William M Baird
Benzo[e]pyrene-induced alterations in the binding of benzo[a]pyrene to DNA in hamster embryo cell cultures.
Carcinogenesis 1984;5(8):1065-9.
1984: William M Baird; C P Salmon; L Diamond
Benzo(e)pyrene-induced alterations in the metabolic activation of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene by hamster embryo cells.
Cancer research 1984;44(4):1445-52.