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Shioko Kimura

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Eric L Snyder; Diana G Wang; Hideo Watanabe; Charles A Whittaker; Tiffany A Chen; Denise Crowley; Sebastian Hoersch; Shioko Kimura; Margaret Magendantz; Matthew Meyerson; Tyler Jacks
Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.
Arjun Guha; Jinjin Guo; Anne Hinds; Jane E Johnson; Shioko Kimura; Guihua Li; Andrew P McMahon; Jill McMahon; Jun Qian; Michelle Vasconcelos; Mitsuhiro Yoneda; Yan Cai; Lauren Dickel; Wellington Cardoso
Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways.
Miyuki Murata; Kousuke Noda; Yasunori Okada; Yoko Ozawa; Wataru Saito; Atsuhiro Kanda; Satoru Kase; Shioko Kimura; Yukihiko Mashima; Satsuki Mochizuki; Junichi Fukuhara; Susumu Ishida
Soluble vascular adhesion protein-1 accumulates in proliferative diabetic retinopathy.

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2013: Eric L Snyder; Diana G Wang; Hideo Watanabe; Charles A Whittaker; Tiffany A Chen; Denise Crowley; Sebastian Hoersch; Shioko Kimura; Margaret Magendantz; Matthew Meyerson; Tyler Jacks
Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.
Molecular cell 2013;50(2):185-99.
2012: Arjun Guha; Jinjin Guo; Anne Hinds; Jane E Johnson; Shioko Kimura; Guihua Li; Andrew P McMahon; Jill McMahon; Jun Qian; Michelle Vasconcelos; Mitsuhiro Yoneda; Yan Cai; Lauren Dickel; Wellington Cardoso
Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(31):12592-7.
2012: Miyuki Murata; Kousuke Noda; Yasunori Okada; Yoko Ozawa; Wataru Saito; Atsuhiro Kanda; Satoru Kase; Shioko Kimura; Yukihiko Mashima; Satsuki Mochizuki; Junichi Fukuhara; Susumu Ishida
Soluble vascular adhesion protein-1 accumulates in proliferative diabetic retinopathy.
Investigative ophthalmology & visual science 2012;53(7):4055-62.
2012: Takashi Ozaki; Samuel Refetoff; Jaime Rodriguez-Canales; Yoshihito Sasaki; Daekwan Seo; Snorri S Thorgeirsson; Jeffrey Hanson; Suguru Hayase; Kennichi Kakudo; Xiao-Hui Liao; Tsutomu Matsubara; Tsubasa Murata; Kunio Nagashima; Minoru Okamoto; Shioko Kimura
Thyroid regeneration: characterization of clear cells after partial thyroidectomy.
Endocrinology 2012;153(5):2514-25.
2012: Shioko Kimura; Jorge Paiz; Charles Vinson; Taketomo Kido; Mitsuhiro Yoneda; Jerrold M Ward
Deficiency of CCAAT/enhancer binding protein family DNA binding prevents malignant conversion of adenoma to carcinoma in NNK-induced lung carcinogenesis in the mouse.
Molecular cancer 2012;11():90.
2011: Chi Iou Lin; Francis D Moore; Zachary S Morris; Matthew A Nehs; Justine A Barletta; David B Donner; Jae-wook Jeong; Shioko Kimura; Edward E Whang; Daniel T Ruan
Thyroid-specific knockout of the tumor suppressor mitogen-inducible gene 6 activates epidermal growth factor receptor signaling pathways and suppresses nuclear factor-κB activity.
Surgery 2011;150(6):1295-302.
2011: Alex Dranovsky; Shioko Kimura; E David Leonardo; Tiffany Moadel; Alyssa M Picchini; Alexander C Sisti; Atsushi Yamada; Rene Hen
Experience dictates stem cell fate in the adult hippocampus.
Neuron 2011;70(5):908-23.
2011: Reiko Kurotani; Satoshi Okumura; Tsutomu Matsubara; Utako Yokoyama; John R Buckley; Takeshi Tomita; Kyohei Kezuka; Tomokazu Nagano; Dominic Esposito; Troy E Taylor; William K Gillette; Yoshihiro Ishikawa; Hiroyuki Abe; Jerrold M Ward; Shioko Kimura
Secretoglobin 3A2 suppresses bleomycin-induced pulmonary fibrosis by transforming growth factor beta signaling down-regulation.
The Journal of biological chemistry 2011;286(22):19682-92.
2011: Taketomo Kido; Takeshi Tomita; Minoru Okamoto; Yan Cai; Yoshimi Matsumoto; Charles Vinson; Yoshiro Maru; Shioko Kimura
FOXA1 plays a role in regulating secretoglobin 1a1 expression in the absence of CCAAT/enhancer binding protein activities in lung in vivo.
American journal of physiology. Lung cellular and molecular physiology 2011;300(3):L441-52.
2011: Aime T Franco; Roberta Malaguarnera; Samuel Refetoff; Xiao-Hui Liao; Emma Lundsmith; Shioko Kimura; Catrin Pritchard; Richard Marais; Terry F Davies; Lee S Weinstein; Min Chen; Neal Rosen; Ronald A Ghossein; Jeffrey A Knauf; James A Fagin
Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(4):1615-20.
2011: Sangmi Ock; Shioko Kimura; Seok Hong Lee; Tae Jin Lee; E Dale Abel; Jihyun Ahn; Chung-Hyun Cho; Jaetaek Kim
Conditional deletion of insulin receptor in thyrocytes does not affect thyroid structure and function.
Endocrine journal 2011;58(11):1013-9.
2011: Marie Gilbert-Sirieix; Shioko Kimura; Joelle Makoukji; Charbel Massaad; Bernard Caillou; Monique Talbot; Liliane Massaad-Massade
Wnt/β-catenin signaling pathway is a direct enhancer of thyroid transcription factor-1 in human papillary thyroid carcinoma cells.
PloS one 2011;6(7):e22280.
2011: Shioko Kimura
Thyroid-specific transcription factors and their roles in thyroid cancer.
Journal of thyroid research 2011;2011():710213.
2011: Takashi Ozaki; Kunio Nagashima; Takashi Kusakabe; Kennichi Kakudo; Shioko Kimura
Development of thyroid gland and ultimobranchial body cyst is independent of p63.
Laboratory investigation; a journal of technical methods and pathology 2011;91(1):138-46.
2011: Reiko Kurotani; Nobue Kumaki; Xu Naizhen; Jerrold M Ward; R Ilona Linnoila; Shioko Kimura
Secretoglobin 3A2/uteroglobin-related protein 1 is a novel marker for pulmonary carcinoma in mice and humans.
Lung cancer (Amsterdam, Netherlands) 2011;71(1):42-8.
2010: Yoshihiko Chiba; Miki Tanabe; Hiroyasu Sakai; Shioko Kimura; Miwa Misawa
A functional interaction between CPI-17 and RACK1 proteins in bronchial smooth muscle cells.
Biochemical and biophysical research communications 2010;401(3):487-90.
2010: Kumiko Goto; Yoshihiko Chiba; Kimihiko Matsusue; Yoshiyuki Hattori; Yoshie Maitani; Hiroyasu Sakai; Shioko Kimura; Miwa Misawa
The proximal STAT6 and NF-kappaB sites are responsible for IL-13- and TNF-alpha-induced RhoA transcriptions in human bronchial smooth muscle cells.
Pharmacological research : the official journal of the Italian Pharmacological Society 2010;61(5):466-72.
2010: Pierre Flandin; Shioko Kimura; John L R Rubenstein
The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(8):2812-23.
2010: Yoshihiko Chiba; Kumiko Goto; Kimihiko Matsusue; Shioko Kimura; Miwa Misawa
Identification and characterization of rat RhoA gene promoter.
Journal of pharmacological sciences 2010;112(4):467-72.
2009: Sayuri Hoshi; Nobuo Hoshi; Minoru Okamoto; Jorge Paiz; Takashi Kusakabe; Jerrold M Ward; Shioko Kimura
Role of NKX2-1 in N-bis(2-hydroxypropyl)-nitrosamine-induced thyroid adenoma in mice.
Carcinogenesis 2009;30(9):1614-9.
2009: Takeshi Tomita; Atsushi Yamada; Masaaki Miyakoshi; Taketomo Kido; Faruk Sheikh; Achara Srisodsai; Atsushi Miyajima; Raymond P Donnelly; Shioko Kimura
Oncostatin M regulates secretoglobin 3A1 and 3A2 expression in a bidirectional manner.
American journal of respiratory cell and molecular biology 2009;40(5):620-30.
2009: Atsushi Yamada; Dai Suzuki; Agasa Miyazono; Kumiko Oshima; Akihide Kamiya; Baohong Zhao; Masamichi Takami; Raymond P Donnelly; Hiroyuki Itabe; Matsuo Yamamoto; Shioko Kimura; Ryutaro Kamijo
IFN-gamma down-regulates Secretoglobin 3A1 gene expression.
Biochemical and biophysical research communications 2009;379(4):964-8.
2008: Motoko Tachihara-Yoshikawa; Takashi Ishida; Kana Watanabe; Aya Sugawara; Kenya Kanazawa; Ryuzo Kanno; Toshimitsu Suzuki; Tomoaki Niimi; Shioko Kimura; Mitsuru Munakata
Expression of secretoglobin3A2 (SCGB3A2) in primary pulmonary carcinomas.
Fukushima journal of medical science 2008;54(2):61-72.
2008: Takeshi Tomita; Taketomo Kido; Reiko Kurotani; Shun-ichiro Iemura; Esta Sterneck; Tohru Natsume; Charles Vinson; Shioko Kimura
CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression.
The Journal of biological chemistry 2008;283(37):25617-27.
2008: Sandrina Nóbrega-Pereira; Nicoletta Kessaris; Tonggong Du; Shioko Kimura; Stewart A Anderson; Oscar Marín
Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors.
Neuron 2008;59(5):733-45.
2008: Simon J B Butt; Vitor H Sousa; Marc Fuccillo; Jens Hjerling-Leffler; Goichi Miyoshi; Shioko Kimura; Gord Fishell
The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes.
Neuron 2008;59(5):722-32.
2008: Reiko Kurotani; Takeshi Tomita; Qian Yang; Bradley A Carlson; Chi Chen; Shioko Kimura
Role of secretoglobin 3A2 in lung development.
American journal of respiratory and critical care medicine 2008;178(4):389-98.
2008: Takeshi Tomita; Shioko Kimura
Regulation of mouse Scgb3a1 gene expression by NF-Y and association of CpG methylation with its tissue-specific expression.
BMC molecular biology 2008;9():5.
2007: Nobuo Hoshi; Takashi Kusakabe; Barbara J Taylor; Shioko Kimura
Side population cells in the mouse thyroid exhibit stem/progenitor cell-like characteristics.
Endocrinology 2007;148(9):4251-8.
2007: Chi Chen; Xiaochao Ma; Michael A Malfatti; Kristopher W Krausz; Shioko Kimura; James S Felton; Jeffrey R Idle; Frank J Gonzalez
A comprehensive investigation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism in the mouse using a multivariate data analysis approach.
Chemical research in toxicology 2007;20(3):531-42.
2006: Qian Yang; Reiko Kurotani; Atsushi Yamada; Shioko Kimura; Frank J Gonzalez
Peroxisome proliferator-activated receptor alpha activation during pregnancy severely impairs mammary lobuloalveolar development in mice.
Endocrinology 2006;147(10):4772-80.
2006: Mariko Shin; Insook Kim; Yusuke Inoue; Shioko Kimura; Frank J Gonzalez
Regulation of mouse hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme in the tryptophan-nicotinamide adenine dinucleotide pathway, by hepatocyte nuclear factor 4alpha and peroxisome proliferator-activated receptor alpha.
Molecular pharmacology 2006;70(4):1281-90.
2006: Takashi Kusakabe; Akio Kawaguchi; Nobuo Hoshi; Rumi Kawaguchi; Sayuri Hoshi; Shioko Kimura
Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid.
Molecular endocrinology (Baltimore, Md.) 2006;20(8):1796-809.
2006: Yoshihiko Chiba; Reiko Kurotani; Takashi Kusakabe; Tomiko Miura; Benjamin W Link; Miwa Misawa; Shioko Kimura
Uteroglobin-related protein 1 expression suppresses allergic airway inflammation in mice.
American journal of respiratory and critical care medicine 2006;173(9):958-64.
2006: Takashi Kusakabe; Nobuo Hoshi; Shioko Kimura
Origin of the ultimobranchial body cyst: T/ebp/Nkx2.1 expression is required for development and fusion of the ultimobranchial body to the thyroid.
Developmental dynamics : an official publication of the American Association of Anatomists 2006;235(5):1300-9.
2006: Qian Yang; Atsushi Yamada; Shioko Kimura; Jeffrey M Peters; Frank J Gonzalez
Alterations in skin and stratified epithelia by constitutively activated PPARalpha.
The Journal of investigative dermatology 2006;126(2):374-85.
2005: Atsushi Yamada; Faruk Sheikh; Tomoaki Niimi; Francesco J DeMayo; Achsah D Keegan; Raymond P Donnelly; Shioko Kimura
Induction of uteroglobin-related protein 2 (Ugrp2) gene expression by the Th2 cytokines IL-4 and IL-13.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):5708-15.
2005: Connie Cheung; Xiaochao Ma; Kristopher W Krausz; Shioko Kimura; Lionel Feigenbaum; Timothy P Dalton; Daniel W Nebert; Jeffrey R Idle; Frank J Gonzalez
Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2.
Chemical research in toxicology 2005;18(9):1471-8.
2005: Atsushi Yamada; Shioko Kimura
Induction of uteroglobin-related protein 2 (Ugrp2) expression by EGF and TGFalpha.
FEBS letters 2005;579(10):2221-5.
2005: Yoshihiko Chiba; Achara Srisodsai; Porntip Supavilai; Shioko Kimura
Interleukin-5 reduces the expression of uteroglobin-related protein (UGRP) 1 gene in allergic airway inflammation.
Immunology letters 2005;97(1):123-9.
2004: Achara Srisodsai; Reiko Kurotani; Yoshihiko Chiba; Faruk Sheikh; Howard A Young; Raymond P Donnelly; Shioko Kimura
Interleukin-10 induces uteroglobin-related protein (UGRP) 1 gene expression in lung epithelial cells through homeodomain transcription factor T/EBP/NKX2.1.
The Journal of biological chemistry 2004;279(52):54358-68.
2004: Yoshihiko Chiba; Takashi Kusakabe; Shioko Kimura
Decreased expression of uteroglobin-related protein 1 in inflamed mouse airways is mediated by IL-9.
American journal of physiology. Lung cellular and molecular physiology 2004;287(6):L1193-8.
2004: Takashi Kusakabe; Akio Kawaguchi; Rumi Kawaguchi; Lionel Feigenbaum; Shioko Kimura
Thyrocyte-specific expression of Cre recombinase in transgenic mice.
Genesis (New York, N.Y. : 2000) 2004;39(3):212-6.
2003: Shioko Kimura
[Homeodomain transcription factor T/EBP/NKX2.1 in development and differentiation of the thyroid and lung].
Seikagaku. The Journal of Japanese Biochemical Society 2003;75(12):1493-504.
2003: Sun Hee Yim; Jerrold M Ward; Yvonne P Dragan; Atsushi Yamada; Peter C Scacheri; Shioko Kimura; Frank J Gonzalez
Microarray analysis using amplified mRNA from laser capture microdissection of microscopic hepatocellular precancerous lesions and frozen hepatocellular carcinomas reveals unique and consistent gene expression profiles.
Toxicologic pathology 2003;31(3):295-303.
2003: Shioko Kimura; Mayumi Kawabe; Aiming Yu; Hideki Morishima; Pedro Fernandez-Salguero; George J Hammons; Jerrold M Ward; Fred F Kadlubar; Frank J Gonzalez
Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2.
Carcinogenesis 2003;24(3):583-7.
2003: Frank J Gonzalez; Shioko Kimura
Study of P450 function using gene knockout and transgenic mice.
Archives of biochemistry and biophysics 2003;409(1):153-8.
2002: Tomoaki Niimi; Mitsuru Munakata; Catherine L Keck-Waggoner; Nicholas C Popescu; Roy Levitt; Michie Hisada; Shioko Kimura
A polymorphism in the human UGRP1 gene promoter that regulates transcription is associated with an increased risk of asthma.
American journal of human genetics 2002;70(3):718-25.
2002: Tomoaki Niimi; Neal G Copeland; D J Gilbert; N A Jenkins; Achara Srisodsai; Drazen Zimonjic; Catherine L Keck-Waggoner; Nicholas C Popescu; Shioko Kimura
Cloning, expression, and chromosomal localization of the mouse gene (Scgb3a1, alias Ugrp2) that encodes a member of the novel uteroglobin-related protein gene family.
Cytogenetic and genome research 2002;97(1-2):120-7.
2001: Tomoaki Niimi; Catherine L Keck-Waggoner; Nicholas C Popescu; Y Zhou; Roy Levitt; Shioko Kimura
UGRP1, a uteroglobin/Clara cell secretory protein-related protein, is a novel lung-enriched downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor.
Molecular endocrinology (Baltimore, Md.) 2001;15(11):2021-36.
2001: Frank J Gonzalez; Shioko Kimura
Understanding the role of xenobiotic-metabolism in chemical carcinogenesis using gene knockout mice.
Mutation research 2001;477(1-2):79-87.
2001: Javier Corchero; Satish Pimprale; Shioko Kimura; Frank J Gonzalez
Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation.
Pharmacogenetics 2001;11(1):1-6.
2000: T Ueno; S Tamura; W I Frels; Magang Shou; Frank J Gonzalez; Shioko Kimura
A transgenic mouse expressing human CYP1A2 in the pancreas.
Biochemical pharmacology 2000;60(6):857-63.
1999: Shioko Kimura; M Kawabe; Jerrold M Ward; Hideki Morishima; Fred F Kadlubar; George J Hammons; Pedro Fernandez-Salguero; Frank J Gonzalez
CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice.
Carcinogenesis 1999;20(9):1825-30.
1999: M Miyata; G Kudo; Y H Lee; TJ Yang; Harry V Gelboin; Pedro Fernandez-Salguero; Shioko Kimura; Frank J Gonzalez
Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene.
The Journal of biological chemistry 1999;274(34):23963-8.
1999: J M Peters; Hideki Morishima; Jerrold M Ward; C J Coakley; Shioko Kimura; Frank J Gonzalez
Role of CYP1A2 in the toxicity of long-term phenacetin feeding in mice.
Toxicological sciences : an official journal of the Society of Toxicology 1999;50(1):82-9.
1998: H Oguchi; Shioko Kimura
Multiple transcripts encoded by the thyroid-specific enhancer-binding protein (T/EBP)/thyroid-specific transcription factor-1 (TTF-1) gene: evidence of autoregulation.
Endocrinology 1998;139(4):1999-2006.
1996: Shioko Kimura
Thyroid-specific enhancer-binding protein Role in thyroid function and organogenesis.
Trends in endocrinology and metabolism: TEM 1996;7(7):247-52.
1996: Jeroen Buters; B K Tang; Thierry Pineau; Harry V Gelboin; Shioko Kimura; Frank J Gonzalez
Role of CYP1A2 in caffeine pharmacokinetics and metabolism: studies using mice deficient in CYP1A2.
Pharmacogenetics 1996;6(4):291-6.
1995: Pedro Fernandez-Salguero; Thierry Pineau; David M Hilbert; T McPhail; S S Lee; Shioko Kimura; Daniel W Nebert; Stuart Rudikoff; Jerrold M Ward; Frank J Gonzalez
Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor.
Science (New York, N.Y.) 1995;268(5211):722-6.
1994: P J Wedlund; Shioko Kimura; Frank J Gonzalez; Daniel W Nebert
1462V mutation in the human CYP1A1 gene: lack of correlation with either the Msp I 1.9 kb (M2) allele or CYP1A1 inducibility in a three-generation family of east Mediterranean descent.
Pharmacogenetics 1994;4(1):21-6.
1993: H Yokota; S Tamura; H Furuya; Shioko Kimura; M Watanabe; I Kanazawa; I Kondo; Frank J Gonzalez
Evidence for a new variant CYP2D6 allele CYP2D6J in a Japanese population associated with lower in vivo rates of sparteine metabolism.
Pharmacogenetics 1993;3(5):256-63.
1990: N Hanioka; Shioko Kimura; Urs A Meyer; Frank J Gonzalez
The human CYP2D locus associated with a common genetic defect in drug oxidation: a G1934----A base change in intron 3 of a mutant CYP2D6 allele results in an aberrant 3' splice recognition site.
American journal of human genetics 1990;47(6):994-1001.
1989: Shioko Kimura; M Umeno; Radek C Skoda; Urs A Meyer; Frank J Gonzalez
The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene.
American journal of human genetics 1989;45(6):889-904.
1989: Shioko Kimura; James P Hardwick; C A Kozak; Frank J Gonzalez
The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes.
DNA (Mary Ann Liebert, Inc.) 1989;8(7):517-25.
1989: Shioko Kimura; N Hanioka; E Matsunaga; Frank J Gonzalez
The rat clofibrate-inducible CYP4A gene subfamily. I. Complete intron and exon sequence of the CYP4A1 and CYP4A2 genes, unique exon organization, and identification of a conserved 19-bp upstream element.
DNA (Mary Ann Liebert, Inc.) 1989;8(7):503-16.
1988: Frank J Gonzalez; Radek C Skoda; Shioko Kimura; M Umeno; Uli Zanger; Daniel W Nebert; Harry V Gelboin; James P Hardwick; Urs A Meyer
Characterization of the common genetic defect in humans deficient in debrisoquine metabolism.
Nature 1988;331(6155):442-6.
1987: Shioko Kimura; Hana Haleem-Smith; O Hankinson; Daniel W Nebert
Analysis of two benzo[a]pyrene-resistant mutants of the mouse hepatoma Hepa-1 P(1)450 gene via cDNA expression in yeast.
The EMBO journal 1987;6(7):1929-33.