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Yoshiyuki Kimura

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Yoshiyuki Kimura; Maho Sumiyoshi
Anti-tumor and anti-metastatic actions of wogonin isolated from Scutellaria baicalensis roots through anti-lymphangiogenesis.
Maho Sumiyoshi; Yoshiyuki Kimura
Hop (Humulus lupulus L.) extract inhibits obesity in mice fed a high-fat diet over the long term.
Yoshiyuki Kimura; Maho Sumiyoshi; Tomoiki Tamaki
Effects of the extracts and an active compound curcumenone isolated from Curcuma zedoaria rhizomes on alcohol-induced drunkenness in mice.

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2013: Yoshiyuki Kimura; Maho Sumiyoshi
Anti-tumor and anti-metastatic actions of wogonin isolated from Scutellaria baicalensis roots through anti-lymphangiogenesis.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2013;20(3-4):328-36.
2013: Maho Sumiyoshi; Yoshiyuki Kimura
Hop (Humulus lupulus L.) extract inhibits obesity in mice fed a high-fat diet over the long term.
The British journal of nutrition 2013;109(1):162-72.
2013: Yoshiyuki Kimura; Maho Sumiyoshi; Tomoiki Tamaki
Effects of the extracts and an active compound curcumenone isolated from Curcuma zedoaria rhizomes on alcohol-induced drunkenness in mice.
Fitoterapia 2013;84():163-9.
2012: Yoshiyuki Kimura; Maho Sumiyoshi
Effects of an Atractylodes lancea rhizome extract and a volatile component β-eudesmol on gastrointestinal motility in mice.
Journal of ethnopharmacology 2012;141(1):530-6.
2012: Yoshiyuki Kimura; Maho Sumiyoshi; Masahiro Sakanaka
Effects of ginsenoside Rb₁ on skin changes.
Journal of biomedicine & biotechnology 2012;2012():946242.
2011: Yoshiyuki Kimura; Maho Sumiyoshi
Effects of various flavonoids isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice.
The Journal of pharmacy and pharmacology 2011;63(12):1613-23.
2011: Yoshiyuki Kimura; Maho Sumiyoshi
Effects of Swertia japonica extract and its main compound swertiamarin on gastric emptying and gastrointestinal motility in mice.
Fitoterapia 2011;82(6):827-33.
2011: Yoshiyuki Kimura; Maho Sumiyoshi
Effects of baicalein and wogonin isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice.
European journal of pharmacology 2011;661(1-3):124-32.
2010: Maho Sumiyoshi; Masahiro Sakanaka; Yoshiyuki Kimura
Effects of Red Ginseng extract on allergic reactions to food in Balb/c mice.
Journal of ethnopharmacology 2010;132(1):206-12.
2010: Maho Sumiyoshi; Yoshiyuki Kimura
Enhancing effects of a chromone glycoside, eucryphin, isolated from Astilbe rhizomes on burn wound repair and its mechanism.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2010;17(10):820-9.
2010: Yoshiyuki Kimura; Maho Sumiyoshi
French maritime pine bark (Pinus maritima Lam.) extract (Flavangenol) prevents chronic UVB radiation-induced skin damage and carcinogenesis in melanin-possessing hairless mice.
Photochemistry and photobiology 2010;86(4):955-63.
2010: Maho Sumiyoshi; Yoshiyuki Kimura
Effects of olive leaf extract and its main component oleuroepin on acute ultraviolet B irradiation-induced skin changes in C57BL/6J mice.
Phytotherapy research : PTR 2010;24(7):995-1003.
2010: Maho Sumiyoshi; Masahiro Sakanaka; Yoshiyuki Kimura
Chronic intake of a high-cholesterol diet resulted in hepatic steatosis, focal nodular hyperplasia and fibrosis in non-obese mice.
The British journal of nutrition 2010;103(3):378-85.
2009: Maho Sumiyoshi; Yoshiyuki Kimura
Effects of a turmeric extract (Curcuma longa) on chronic ultraviolet B irradiation-induced skin damage in melanin-possessing hairless mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2009;16(12):1137-43.
2009: Yoshiyuki Kimura; Maho Sumiyoshi
Olive leaf extract and its main component oleuropein prevent chronic ultraviolet B radiation-induced skin damage and carcinogenesis in hairless mice.
The Journal of nutrition 2009;139(11):2079-86.
2009: Maho Sumiyoshi; Teruaki Hayashi; Yoshiyuki Kimura
Effects of the nonsugar fraction of brown sugar on chronic ultraviolet B irradiation-induced photoaging in melanin-possessing hairless mice.
Journal of natural medicines 2009;63(2):130-6.
2008: Wencong Liu; Yinan Zheng; Likun Han; Haimin Wang; Masato Saito; Mingsong Ling; Yoshiyuki Kimura; Yixiong Feng
Saponins (Ginsenosides) from stems and leaves of Panax quinquefolium prevented high-fat diet-induced obesity in mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2008;15(12):1140-5.
2008: Yoshiyuki Kimura; Maho Sumiyoshi; Masahiko Taniguchi; Kimiye Baba
Antitumor and antimetastatic actions of anthrone-C-glucoside, cassialoin isolated from Cassia garrettiana heartwood in colon 26-bearing mice.
Cancer science 2008;99(11):2336-48.
2008: Young Gon Kim; Maho Sumiyoshi; Kazuhiro Kawahira; Masahiro Sakanaka; Yoshiyuki Kimura
Effects of Red Ginseng extract on ultraviolet B-irradiated skin change in C57BL mice.
Phytotherapy research : PTR 2008;22(11):1423-7.
2008: Yoshiyuki Kimura; Maho Sumiyoshi; Kimiye Baba
Antitumor activities of synthetic and natural stilbenes through antiangiogenic action.
Cancer science 2008;99(10):2083-96.
2008: Yoshiyuki Kimura; Maho Sumiyoshi; Masahiko Taniguchi; Kimiye Baba
Antitumor actions of a chromone glucoside cnidimoside A isolated from Cnidium japonicum.
Journal of natural medicines 2008;62(3):308-13.
2008: Yoshiyuki Kimura; Maho Sumiyoshi; Kimiye Baba
Anti-tumor actions of major component 3'-O-acetylhamaudol of Angelica japonica roots through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation.
Cancer letters 2008;265(1):84-97.
2008: Kazuhiro Kawahira; Maho Sumiyoshi; Masahiro Sakanaka; Yoshiyuki Kimura
Effects of ginsenoside Rb1 at low doses on histamine, substance P, and monocyte chemoattractant protein 1 in the burn wound areas during the process of acute burn wound repair.
Journal of ethnopharmacology 2008;117(2):278-84.
2008: Yoshiyuki Kimura; Maho Sumiyoshi; Kei-Ichi Samukawa; Noriko Satake; Masahiro Sakanaka
Facilitating action of asiaticoside at low doses on burn wound repair and its mechanism.
European journal of pharmacology 2008;584(2-3):415-23.
2008: Jiang-Ning Hu; Xue-Mei Zhu; Li-Kun Han; Masato Saito; Yin-Shi Sun; Masayuki Yoshikawa; Yoshiyuki Kimura; Yi-Nan Zheng
Anti-obesity effects of escins extracted from the seeds of Aesculus turbinata BLUME (Hippocastanaceae).
Chemical & pharmaceutical bulletin 2008;56(1):12-6.
2007: Yoshiyuki Kimura; Maho Sumiyoshi; Toshio Suzuki; Toshio Suzuki; Masahiro Sakanaka
Effects of water-soluble low-molecular-weight beta-1, 3-D-glucan (branch beta-1, 6) isolated from Aureobasidium pullulans 1A1 strain black yeast on restraint stress in mice.
The Journal of pharmacy and pharmacology 2007;59(8):1137-44.
2007: Yoshiyuki Kimura; Maho Sumiyoshi; Toshio Suzuki; Toshio Suzuki; Masahiro Sakanaka
Inhibitory effects of water-soluble low-molecular-weight beta-(1,3-1,6) d-glucan purified from Aureobasidium pullulans GM-NH-1A1 strain on food allergic reactions in mice.
International immunopharmacology 2007;7(7):963-72.
2007: Yoshiyuki Kimura; Maho Sumiyoshi; Masahiro Sakanaka
Effects of Astilbe thunbergii rhizomes on wound healing Part 1. Isolation of promotional effectors from Astilbe thunbergii rhizomes on burn wound healing.
Journal of ethnopharmacology 2007;109(1):72-7.
2007: Yoshiyuki Kimura; Maho Sumiyoshi
High-fat, high-sucrose, and high-cholesterol diets accelerate tumor growth and metastasis in tumor-bearing mice.
Nutrition and cancer 2007;59(2):207-16.
2006: Li-Kun Han; Rumiko Nose; Wei Li; Xiao-Jie Gong; Yi-Nan Zheng; Masayuki Yoshikawa; Kazuo Koike; Tamotsu Nikaido; Hiromichi Okuda; Yoshiyuki Kimura
Reduction of fat storage in mice fed a high-fat diet long term by treatment with saponins prepared from Kochia scoparia fruit.
Phytotherapy research : PTR 2006;20(10):877-82.
2006: Yoshiyuki Kimura; Maho Sumiyoshi; Kazuhiro Kawahira; Masahiro Sakanaka
Effects of ginseng saponins isolated from Red Ginseng roots on burn wound healing in mice.
British journal of pharmacology 2006;148(6):860-70.
2006: Maho Sumiyoshi; Masahiro Sakanaka; Yoshiyuki Kimura
Chronic intake of high-fat and high-sucrose diets differentially affects glucose intolerance in mice.
The Journal of nutrition 2006;136(3):582-7.
2006: Maho Sumiyoshi; Yoshiyuki Kimura
Low molecular weight chitosan inhibits obesity induced by feeding a high-fat diet long-term in mice.
The Journal of pharmacy and pharmacology 2006;58(2):201-7.
2005: Yi-Nan Zheng; Jing Zhang; Li-Kun Han; Keizo Sekiya; Yoshiyuki Kimura; Hiromichi Okuda
Effects of compounds in leaves of Salix matsudana on arachidonic acid metabolism.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2005;125(12):1005-8.
2005: Li-Kun Han; Xiao-Jie Gong; Shiho Kawano; Masato Saito; Yoshiyuki Kimura; Hiromichi Okuda
[Antiobesity actions of Zingiber officinale Roscoe].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2005;125(2):213-7.
2005: Li-Kun Han; Yi-Nan Zheng; Masayuki Yoshikawa; Hiromichi Okuda; Yoshiyuki Kimura
Anti-obesity effects of chikusetsusaponins isolated from Panax japonicus rhizomes.
BMC complementary and alternative medicine 2005;5():9.
2005: Yoshiyuki Kimura
New anticancer agents: in vitro and in vivo evaluation of the antitumor and antimetastatic actions of various compounds isolated from medicinal plants.
In vivo (Athens, Greece) 2005;19(1):37-60.
2004: Yoshiyuki Kimura; Maho Sumiyoshi
Effects of various Eleutherococcus senticosus cortex on swimming time, natural killer activity and corticosterone level in forced swimming stressed mice.
Journal of ethnopharmacology 2004;95(2-3):447-53.
2004: Kenshi Sakayama; Teruki Kidani; Tatsuhiko Miyazaki; Haruo Shirakata; Yoshiyuki Kimura; Junji Kamogawa; Hiroshi Masuno; Haruyasu Yamamoto
Effect of ketoprofen in topical formulation on vascular endothelial growth factor expression and tumor growth in nude mice with osteosarcoma.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2004;22(6):1168-74.
2004: Yoshiyuki Kimura; Tadashi Kido; Takeshi Takaku; Maho Sumiyoshi; Kimiye Baba
Isolation of an anti-angiogenic substance from Agaricus blazei Murill: its antitumor and antimetastatic actions.
Cancer science 2004;95(9):758-64.
2004: Yoshiyuki Kimura; Masahiko Taniguchi; Kimiye Baba
Antitumor and antimetastatic activities of 4-hydroxyderricin isolated from Angelica keiskei roots.
Planta medica 2004;70(3):211-9.
2003: Li-Kun Han; Maho Sumiyoshi; Yi-Nan Zheng; Hiromichi Okuda; Yoshiyuki Kimura
Anti-obesity action of Salix matsudana leaves (Part 2). Isolation of anti-obesity effectors from polyphenol fractions of Salix matsudana.
Phytotherapy research : PTR 2003;17(10):1195-8.
2003: Li-Kun Han; Maho Sumiyoshi; Jing Zhang; Mo-Xiang Liu; Xin-Feng Zhang; Yi-Nan Zheng; Hiromichi Okuda; Yoshiyuki Kimura
Anti-obesity action of Salix matsudana leaves (Part 1). Anti-obesity action by polyphenols of Salix matsudana in high fat-diet treated rodent animals.
Phytotherapy research : PTR 2003;17(10):1188-94.
2003: Yoshiyuki Kimura; Kimiye Baba
Antitumor and antimetastatic activities of Angelica keiskei roots, part 1: Isolation of an active substance, xanthoangelol.
International journal of cancer. Journal international du cancer 2003;106(3):429-37.
2003: Yoshiyuki Kimura
Pharmacological studies on resveratrol.
Methods and findings in experimental and clinical pharmacology 2003;25(4):297-310.
2002: Yoshiyuki Kimura; Masahiko Taniguchi; Kimiye Baba
Antitumor and antimetastatic effects on liver of triterpenoid fractions of Ganoderma lucidum: mechanism of action and isolation of an active substance.
Anticancer research 2002;22(6A):3309-18.
2002: Li-Kun Han; Yi-Nan Zheng; BAOJUN XU; Hiromichi Okuda; Yoshiyuki Kimura
Saponins from platycodi radix ameliorate high fat diet-induced obesity in mice.
The Journal of nutrition 2002;132(8):2241-5.
2002: Yoshiyuki Kimura
Carp oil or oleic acid, but not linoleic acid or linolenic acid, inhibits tumor growth and metastasis in Lewis lung carcinoma-bearing mice.
The Journal of nutrition 2002;132(7):2069-75.
2001: Yoshiyuki Kimura; N Sawai; Hiromichi Okuda
Antitumour activity and adverse reactions of combined treatment with chitosan and doxorubicin in tumour-bearing mice.
The Journal of pharmacy and pharmacology 2001;53(10):1373-8.
2001: Li-Kun Han; Yoshiyuki Kimura; M Kawashima; Takeshi Takaku; T Taniyama; T Hayashi; Yi-Nan Zheng; Hiromichi Okuda
Anti-obesity effects in rodents of dietary teasaponin, a lipase inhibitor.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(10):1459-64.
2001: Yoshiyuki Kimura; N Matsushita; K Yokoi-Hayashi; Hiromichi Okuda
Effects of baicalein isolated from Scutellaria baicalensis Radix on adhesion molecule expression induced by thrombin and thrombin receptor agonist peptide in cultured human umbilical vein endothelial cells.
Planta medica 2001;67(4):331-4.
2001: Yoshiyuki Kimura; Hiromichi Okuda
Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in Lewis lung carcinoma-bearing mice.
The Journal of nutrition 2001;131(6):1844-9.
2001: Takeshi Takaku; Yoshiyuki Kimura; Hiromichi Okuda
Isolation of an antitumor compound from Agaricus blazei Murill and its mechanism of action.
The Journal of nutrition 2001;131(5):1409-13.
2001: Yoshiyuki Kimura; Takeshi Takaku; S Nakajima; Hiromichi Okuda
Effects of carp and tuna oils on 5-fluorouracil-induced antitumor activity and side effects in sarcoma 180-bearing mice.
Lipids 2001;36(4):353-9.
2001: M Matsuura; Yoshiyuki Kimura; K Nakata; Kimiye Baba; Hiromichi Okuda
Artery relaxation by chalcones isolated from the roots of Angelica keiskei.
Planta medica 2001;67(3):230-5.
2000: Li-Kun Han; BAOJUN XU; Yoshiyuki Kimura; Y n Zheng; Hiromichi Okuda
Platycodi radix affects lipid metabolism in mice with high fat diet-induced obesity.
The Journal of nutrition 2000;130(11):2760-4.
2000: Yoshiyuki Kimura; Hiromichi Okuda
Effects of naturally occurring stilbene glucosides from medicinal plants and wine, on tumour growth and lung metastasis in Lewis lung carcinoma-bearing mice.
The Journal of pharmacy and pharmacology 2000;52(10):1287-95.
2000: Yoshiyuki Kimura; Kimiye Baba; Hiromichi Okuda
Inhibitory effects of active substances isolated from Cassia garrettiana heartwood on tumor growth and lung metastasis in Lewis lung carcinoma-bearing mice (Part 2).
Anticancer research 2000;20(5A):2923-30.
2000: Yoshiyuki Kimura; Kimiye Baba; Hiromichi Okuda
Inhibitory effects of active substances isolated from Cassia garrettiana heartwood on tumor growth and lung metastasis in Lewis lung carcinoma-bearing mice (Part 1).
Anticancer research 2000;20(5A):2899-906.
2000: Li-Kun Han; Maho Sumiyoshi; T Takeda; H Chihara; T Nishikiori; Takahiro Tsujita; Yoshiyuki Kimura; Hiromichi Okuda
Inhibitory effects of chondroitin sulfate prepared from salmon nasal cartilage on fat storage in mice fed a high-fat diet.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24(9):1131-8.
2000: Yoshiyuki Kimura; M Onoyama; T Sera; Hiromichi Okuda
Antitumour activity and side effects of combined treatment with chitosan and cisplatin in sarcoma 180-bearing mice.
The Journal of pharmacy and pharmacology 2000;52(7):883-90.
1999: Yoshiyuki Kimura; Hiromichi Okuda
Prevention by carp extract of myelotoxicity and gastrointestinal toxicity induced by 5-fluorouracil without loss of antitumor activity in mice.
Journal of ethnopharmacology 1999;68(1-3):39-45.
1999: Yoshiyuki Kimura; Hiromichi Okuda
Prevention by chitosan of myelotoxicity, gastrointestinal toxicity and immunocompetent organic toxicity induced by 5-fluorouracil without loss of antitumor activity in mice.
Japanese journal of cancer research : Gann 1999;90(7):765-74.
1999: Li-Kun Han; Yoshiyuki Kimura; Hiromichi Okuda
Reduction in fat storage during chitin-chitosan treatment in mice fed a high-fat diet.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1999;23(2):174-9.
1999: Li-Kun Han; Takeshi Takaku; J Li; Yoshiyuki Kimura; Hiromichi Okuda
Anti-obesity action of oolong tea.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1999;23(1):98-105.
1998: Li-Kun Han; H Ninomiya; M Taniguchi; Kimiye Baba; Yoshiyuki Kimura; Hiromichi Okuda
Norepinephrine-augmenting lipolytic effectors from Astilbe thunbergii rhizomes.
Journal of natural products 1998;61(8):1006-11.
1998: Yoshiyuki Kimura; H Ohminami; Hiromichi Okuda
Effects of extract of oyster on lipid metabolism in rats.
Journal of ethnopharmacology 1998;59(3):117-23.
1997: Yoshiyuki Kimura; K Yokoi; N Matsushita; Hiromichi Okuda
Effects of flavonoids isolated from scutellariae radix on the production of tissue-type plasminogen activator and plasminogen activator inhibitor-1 induced by thrombin and thrombin receptor agonist peptide in cultured human umbilical vein endothelial cells.
The Journal of pharmacy and pharmacology 1997;49(8):816-22.
1997: Yoshiyuki Kimura; N Matsushita; Hiromichi Okuda
Effects of baicalein isolated from Scutellaria baicalensis on interleukin 1 beta- and tumor necrosis factor alpha-induced adhesion molecule expression in cultured human umbilical vein endothelial cells.
Journal of ethnopharmacology 1997;57(1):63-7.
1997: Yoshiyuki Kimura; Hiromichi Okuda; Z Ogita
Effects of flavonoids isolated from scutellariae radix on fibrinolytic system induced by trypsin in human umbilical vein endothelial cells.
Journal of natural products 1997;60(6):598-601.
1997: Yoshiyuki Kimura; Hiromichi Okuda
Histamine-release effectors from Angelica dahurica var. dahurica root.
Journal of natural products 1997;60(3):249-51.
1995: Yoshiyuki Kimura; Hiromichi Okuda; M Kubo
Effects of stilbenes isolated from medicinal plants on arachidonate metabolism and degranulation in human polymorphonuclear leukocytes.
Journal of ethnopharmacology 1995;45(2):131-9.
1989: Yoshiyuki Kimura; Hiromichi Okuda
Effects of active compounds isolated from Angelica shikokiana on lipid metabolism in fat cells.
Journal of ethnopharmacology 1989;25(3):269-80.
1988: Yoshiyuki Kimura; Hiromichi Okuda; S Arichi
Effects of various ginseng saponins on 5-hydroxytryptamine release and aggregation in human platelets.
The Journal of pharmacy and pharmacology 1988;40(12):838-43.
1987: Yoshiyuki Kimura; Hiromichi Okuda; S Arichi
Effects of baicalein on leukotriene biosynthesis and degranulation in human polymorphonuclear leukocytes.
Biochimica et biophysica acta 1987;922(3):278-86.
1987: Kenji Kameda; T Takaku; Hiromichi Okuda; Yoshiyuki Kimura; T Okuda; T Hatano; I Agata; S Arichi
Inhibitory effects of various flavonoids isolated from leaves of persimmon on angiotensin-converting enzyme activity.
Journal of natural products 1987;50(4):680-3.
1987: Yoshiyuki Kimura; Hiromichi Okuda; T Okuda; T Hatano; S Arichi
Studies on the activities of tannins and related compounds, X. Effects of caffeetannins and related compounds on arachidonate metabolism in human polymorphonuclear leukocytes.
Journal of natural products 1987;50(3):392-9.
1985: Yoshiyuki Kimura; Hiromichi Okuda; T Okuda; T Hatano; I Agata; S Arichi
Studies on the activities of tannins and related compounds from medicinal plants and drugs. VII. Effects of extracts of leaves of Artemisia species, and caffeic acid and chlorogenic acid on lipid metabolic injury in rats fed peroxidized oil.
Chemical & pharmaceutical bulletin 1985;33(5):2028-34.
1985: Yoshiyuki Kimura; Hiromichi Okuda; T Okuda; T Hatano; I Agata; S Arichi
Studies on the activities of tannins and related compounds from medicinal plants and drugs. VI. Inhibitory effects of caffeoylquinic acids on histamine release from rat peritoneal mast cells.
Chemical & pharmaceutical bulletin 1985;33(2):690-6.
1984: Yoshiyuki Kimura; Hiromichi Okuda; T Okuda; T Hatano; I Agata; S Arichi
Studies on the activities of tannins and related compounds; V. Inhibitory effects on lipid peroxidation in mitochondria and microsomes of liver.
Planta medica 1984;50(6):473-7.