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David Kingston

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Cao Shugeng; Brodie Peggy; Callmander Martin; Randrianaivo Richard; Razafitsalama Jeremi; Rakotobe Etienne; Rasamison Vincent E; TenDyke Karen; Shen Yongchun; Suh Edward M; Kingston David G I
Antiproliferative triterpenoid saponins of Dodonaea viscosa from the Madagascar dry forest.
Murphy Brian T; Cao Shugeng; Brodie Peggy; Maharavo Jean; Andriamanantoanina Hanta; Ravelonandro Pierre; Kingston David G I
Antiproliferative bistramides from Trididemnum cyclops from Madagascar (1).
Hodge Mathis; Chen Qiao-Hong; Bane Susan; Sharma Shubhada; Loew Maura; Banerjee Abhijit; Alcaraz Ana A; Snyder James P; Kingston David G I
Synthesis and bioactivity of a side chain bridged paclitaxel: A test of the T-Taxol conformation.

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All Publications

2009: Cao Shugeng; Brodie Peggy; Callmander Martin; Randrianaivo Richard; Razafitsalama Jeremi; Rakotobe Etienne; Rasamison Vincent E; TenDyke Karen; Shen Yongchun; Suh Edward M; Kingston David G I
Antiproliferative triterpenoid saponins of Dodonaea viscosa from the Madagascar dry forest.
Journal of natural products 2009;72(9):1705-7.
2009: Murphy Brian T; Cao Shugeng; Brodie Peggy; Maharavo Jean; Andriamanantoanina Hanta; Ravelonandro Pierre; Kingston David G I
Antiproliferative bistramides from Trididemnum cyclops from Madagascar (1).
Journal of natural products 2009;72(7):1338-40.
2009: Hodge Mathis; Chen Qiao-Hong; Bane Susan; Sharma Shubhada; Loew Maura; Banerjee Abhijit; Alcaraz Ana A; Snyder James P; Kingston David G I
Synthesis and bioactivity of a side chain bridged paclitaxel: A test of the T-Taxol conformation.
Bioorganic & medicinal chemistry letters 2009;19(10):2884-7.
2009: Hou Yanpeng; Cao Shugeng; Brodie Peggy J; Callmander Martin W; Ratovoson Fidisoa; Rakotobe Etienne A; Rasamison Vincent E; Ratsimbason Michel; Alumasa John N; Roepe Paul D; Kingston David G I
Antiproliferative and antimalarial anthraquinones of Scutia myrtina from the Madagascar forest.
Bioorganic & medicinal chemistry 2009;17(7):2871-6.
2009: Kingston David G I
Tubulin-interactive natural products as anticancer agents (1).
Journal of natural products 2009;72(3):507-15.
2009: Hou Yanpeng; Cao Shugeng; Brodie Peggy; Callmander Martin; Ratovoson Fidisoa; Randrianaivo Richard; Rakotobe Etienne; Rasamison Vincent E; Rakotonandrasana Stephan; TenDyke Karen; Suh Edward M; Kingston David G I
Antiproliferative cardenolide glycosides of Elaeodendron alluaudianum from the Madagascar Rainforest.
Bioorganic & medicinal chemistry 2009;17(6):2215-8.
2009: Cao Shugeng; Murphy Brian T; Foster Caleb; Lazo John S; Kingston David G I
Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases.
Bioorganic & medicinal chemistry 2009;17(6):2276-81.
2009: Cao Shugeng; Brodie Peggy; Miller James S; Birkinshaw Chris; Rakotondrafara A; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
Antiproliferative compounds of Helmiopsis sphaerocarpa from the Madagascar rainforest.
Natural product research 2009;23(7):638-43.
2008: Chen Qiao-Hong; Ganesh Thota; Brodie Peggy; Slebodnick Carla; Jiang Yi; Banerjee Abhijit; Bane Susan; Snyder James P; Kingston David G I
Design, synthesis and biological evaluation of bridged epothilone D analogues.
Organic & biomolecular chemistry 2008;6(24):4542-52.
2008: Kingston David G I
A natural love of natural products.
The Journal of organic chemistry 2008;73(11):3975-84.
2008: Zhan Weiqiang; Jiang Yi; Brodie Peggy J; Kingston David G I; Liotta Dennis C; Snyder James P
Design and synthesis of C6-C8 bridged epothilone A.
Organic letters 2008;10(8):1565-8.
2008: Leet John E; Liu Xiaohong; Drexler Dieter M; Cantone Joseph L; Huang Stella; Mamber Stephen W; Fairchild Craig R; Hussain Raouf; Newman David J; Kingston David G I
Cytotoxic xanthones from Psorospermum molluscum from the Madagascar rain forest.
Journal of natural products 2008;71(3):460-3.
2008: Murphy Brian T; Brodie Peggie; Slebodnick Carla; Miller James S; Birkinshaw Chris; Randrianjanaka Lucien M; Andriantsiferana Rabodo; Rasamison Vincent E; TenDyke Karen; Suh Edward M; Kingston David G I
Antiproliferative limonoids of a Malleastrum sp. from the Madagascar rainforest.
Journal of natural products 2008;71(3):325-9.
2008: Hou Yanpeng; Cao Shugeng; Brodie Peggy; Miller James S; Birkinshaw Chris; Ratovoson Fidisoa; Rakotondrajaona Roland; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
Antiproliferative cassane diterpenoids of Cordyla madagascariensis ssp. madagascariensis from the Madagascar rainforest.
Journal of natural products 2008;71(1):150-2.
2008: Cao Shugeng; Al-Rehaily Adnan J; Brodie Peggy; Wisse Jan H; Moniz Etienne; Malone Stan; Kingston David G I
Furoquinoline alkaloids of Ertela (Monnieria) trifolia (L.) Kuntze from the Suriname rainforest.
Phytochemistry 2008;69(2):553-7.
2008: Murphy Brian T; Cao Shugeng; Brodie Peggy J; Miller James S; Ratovoson Fidy; Birkinshaw Chris; Rakotobe Etienne; Rasamison Vincent E; Tendyke Karen; Suh Edward M; Kingston David G I
Antiproliferative compounds of Artabotrys madagascariensis from the Madagascar rainforest.
Natural product research 2008;22(13):1169-75.
2007: Karkare Sampada; Adou Eba; Cao Shugeng; Brodie Peggy; Miller James S; Andrianjafy N M; Razafitsalama J; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
Cytotoxic cardenolide glycosides of Roupellina (Strophanthus) boivinii from the Madagascar rainforest.
Journal of natural products 2007;70(11):1766-70.
2007: Shanker Natasha; Kingston David G I; Ganesh Thota; Yang Chao; Alcaraz Ana A; Geballe Matthew T; Banerjee Abhijit; McGee Dennis; Snyder James P; Bane Susan
Enhanced microtubule binding and tubulin assembly properties of conformationally constrained paclitaxel derivatives.
Biochemistry 2007;46(41):11514-27.
2007: Cao Shugeng; Norris Andrew; Wisse Jan H; Miller James S; Evans Randy; Kingston David G I
Ipomoeassin F, a new cytotoxic macrocyclic glycoresin from the leaves of Ipomoea squamosa from the Suriname rainforest.
Natural product research 2007;21(10):872-6.
2007: Kingston David G I
The shape of things to come: structural and synthetic studies of taxol and related compounds.
Phytochemistry 2007;68(14):1844-54.
2007: Cao Shugeng; Brodie Peggy J; Miller James S; Ratovoson Fidy; Callmander Martin W; Randrianasolo Sennen; Rakotobe Etienne; Rasamison Vincent E; Suh Edward M; TenDyke Karen; Kingston David G I
Antiproliferative cardenolides of an Elaeodendron sp. from the Madagascar rain forest(1).
Journal of natural products 2007;70(6):1064-7.
2007: Cao Shugeng; Brodie Peggy J; Miller James S; Ratovoson Fidy; Birkinshaw Chris; Randrianasolo Sennen; Rakotobe Etienne; Rasamison Vincent E; Kingston David G I
Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest.
Journal of natural products 2007;70(4):686-8.
2007: Cao Shugeng; Brodie Peggy J; Miller James S; Randrianaivo Richard; Ratovoson Fidy; Birkinshaw Chris; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest.
Journal of natural products 2007;70(4):679-81.
2007: Kingston David G I; Newman David J
Taxoids: cancer-fighting compounds from nature.
Current opinion in drug discovery & development 2007;10(2):130-44.
2007: Yoder Brent J; Cao Shugeng; Norris Andrew; Miller James S; Ratovoson Fidy; Razafitsalama Jeremi; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
Antiproliferative prenylated stilbenes and flavonoids from Macaranga alnifolia from the Madagascar rainforest.
Journal of natural products 2007;70(3):342-6.
2007: Cao Shugeng; Norris Andrew; Miller James S; Ratovoson Fidy; Razafitsalama Jeremi; Andriantsiferana Rabodo; Rasamison Vincent E; TenDyke Karen; Suh Ted; Kingston David G I
Cytotoxic triterpenoid saponins of Albizia gummifera from the Madagascar rain forest.
Journal of natural products 2007;70(3):361-6.
2007: Williams Russell B; Norris Andrew; Miller James S; Birkinshaw Chris; Ratovoson Fidy; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
Cytotoxic clerodane diterpenoids and their hydrolysis products from Casearia nigrescens from the rainforest of Madagascar.
Journal of natural products 2007;70(2):206-9.
2007: Ganesh Thota; Yang Chao; Norris Andrew; Glass Tom; Bane Susan; Ravindra Rudravajhala; Banerjee Abhijit; Metaferia Belhu; Thomas Shala L; Giannakakou Paraskevi; Alcaraz Ana A; Lakdawala Ami S; Snyder James P; Kingston David G I
Evaluation of the tubulin-bound paclitaxel conformation: synthesis, biology, and SAR studies of C-4 to C-3' bridged paclitaxel analogues.
Journal of medicinal chemistry 2007;50(4):713-25.
2007: Yoder Brent J; Cao Shugeng; Norris Andrew; Miller James S; Ratovoson Fidisoa; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
Tambouranolide, a new cytotoxic hydroxybutanolide from a Tambourissa sp. (Monimiaceae).
Natural product research 2007;21(1):37-41.
2007: Paik Younkee; Yang Chao; Metaferia Belhu; Tang Shoubin; Bane Susan; Ravindra Rudravajhala; Shanker Natasha; Alcaraz Ana A; Johnson Scott A; Schaefer Jacob; O'Connor Robert D; Cegelski Lynette; Snyder James P; Kingston David G I
Rotational-echo double-resonance NMR distance measurements for the tubulin-bound Paclitaxel conformation.
Journal of the American Chemical Society 2007;129(2):361-70.
2007: Sharma Shubhada; Ganesh Thota; Kingston David G I; Bane Susan
Promotion of tubulin assembly by poorly soluble taxol analogs.
Analytical biochemistry 2007;360(1):56-62.
2006: Cao Shugeng; Ranarivelo Lalasoa; Ratsimbason Michel; Randrianasolo Sennen; Ratovoson Fidy; Andrianjafy Mamisoa; Kingston David G I
Antiplasmodial activity of compounds from Sloanea rhodantha (Baker) Capuron var. rhodantha from the Madagascar rain forest.
Planta medica 2006;72(15):1438-40.
2006: Cao Shugeng; Norris Andrew; Miller James S; Ratovoson Fidy; Birkinshaw Chris; Andriantsiferana Rabodo; Rasamison Vincent E; Rakotonandrasana Stephan; Kingston David G I
Cytotoxic compounds of Physena madagascariensis from the Madagascar rain forest paragraph sign.
Natural product research 2006;20(13):1157-63.
2006: Murphy Brian T; Cao Shugeng; Norris Andrew; Miller James S; Ratovoson Fidisoa; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G
Cytotoxic compounds of Schizolaena hystrix from the Madagascar rainforest.
Planta medica 2006;72(13):1235-8.
2006: Tang Shoubin; Yang Chao; Brodie Peggy; Bane Susan; Ravindra Rudravajhala; Sharma Shubhada; Jiang Yi; Snyder James P; Kingston David G I
Bridging converts a noncytotoxic nor-paclitaxel derivative to a cytotoxic analogue by constraining it to the T-Taxol conformation.
Organic letters 2006;8(18):3983-6.
2006: Abdel-Kader Maged S; Amer Masouda E; Tang Shoubin; Kingston David G I
Two new isoflavone derivatives from the roots of an Egyptian collection of Lotus polyphyllos.
Natural product research 2006;20(10):922-6.
2006: Reynolds Micah; Chaturvedula V S Prakash; Ratovoson Fidisoa; Andriantsiferana Rabodo; Rasamison Vincent E; Guza Rebecca C; Kingston David G I
Cytotoxic diterpenoids from Podocarpus madagascariensis from the Madagascar rainforest.
Natural product research 2006;20(6):606-10.
2006: Williams Russell B; Norris Andrew; Miller James S; Razafitsalama L Jeremie; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G
Two new cytotoxic naphthoquinones from Mendoncia cowanii from the rainforest of Madagascar.
Planta medica 2006;72(6):564-6.
2006: Ganesh Thota; Norris Andrew; Sharma Shubhada; Bane Susan; Alcaraz Ana A; Snyder James P; Kingston David G I
Design, synthesis, and bioactivity of simplified paclitaxel analogs based on the T-Taxol bioactive conformation.
Bioorganic & medicinal chemistry 2006;14(10):3447-54.
2006: Karliga Bekir; Schilling Jennifer K; Kingston David G I; Bane Susan; Ravindra Rudy; Talinli Naciye
Synthesis and biological evaluation of N-(arylsulfanyl)carbonyl analogues of paclitaxel (taxol).
Chemistry & biodiversity 2006;3(4):396-404.
2006: Clement Jason A; Li Mei; Hecht Sidney M; Kingston David G I
Bioactive isomalabaricane triterpenoids from Rhabdastrella globostellata that stabilize the binding of DNA polymerase beta to DNA.
Journal of natural products 2006;69(3):373-6.
2006: Chaturvedula V S Prakash; Norris Andrew; Miller James S; Ratovoson Fidisoa; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
Cytotoxic diterpenes from Cassipourea madagascariensis from the Madagascar rainforest.
Journal of natural products 2006;69(2):287-9.
2006: Cao Shugeng; Radwan Mohamed M; Norris Andrew; Miller James S; Ratovoson Fidy; Mamisoa Andrianjafy; Andriantsiferana Rabodo; Rasamison Vincent E; Rakotonandrasana Stephan; Kingston David G I
Cytotoxic and other compounds from Didymochlaena truncatula from the Madagascar rain forest.
Journal of natural products 2006;69(2):284-6.
2005: Adou Eba; Williams Russell B; Schilling Jennifer K; Malone Stan; Meyer Jan; Wisse Jan H; Frederik Djon; Koese Delon; Werkhoven Marga C M; Snipes Carl E; Werk Todd L; Kingston David G I
Cytotoxic diterpenoids from two lianas from the Suriname rainforest.
Bioorganic & medicinal chemistry 2005;13(21):6009-14.
2005: Cao Shugeng; Foster Caleb; Lazo John S; Kingston David G I
Four diterpenoid inhibitors of Cdc25B phosphatase from a marine anemone.
Bioorganic & medicinal chemistry 2005;13(20):5830-4.
2005: Williams Russell B; Norris Andrew; Slebodnick Carla; Merola Joseph; Miller James S; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
Cytotoxic sesquiterpene lactones from Vernonia pachyclada from the Madagascar rainforest.
Journal of natural products 2005;68(9):1371-4.
2005: Cao Shugeng; Foster Caleb; Lazo John S; Kingston David G I
Sesterterpenoids and an alkaloid from a Thorectandra sp. as inhibitors of the phosphatase Cdc25B.
Bioorganic & medicinal chemistry 2005;13(17):5094-8.
2005: Gören Ahmet C; Zhou Bing-Nan; Topçu Gülaçti; Kökdil Gamze; Kingston David G I
DNA damaging activities of methanol extract of Ajuga postii and iridoid glucoside reptoside.
Natural product research 2005;19(5):457-60.
2005: Bahçeevli Arzu Küçükosmanogiu; Kurucu Semra; Kolak Ufuk; Topçu Gülaçti; Adou Eba; Kingston David G I
Alkaloids and aromatics of Cyathobasis fruticulosa (Bunge) Aellen.
Journal of natural products 2005;68(6):956-8.
2005: Cao Shugeng; Guza Rebecca C; Wisse Jan H; Miller James S; Evans Randy; Kingston David G I
Ipomoeassins A-E, cytotoxic macrocyclic glycoresins from the leaves of Ipomoea squamosa from the Suriname rainforest.
Journal of natural products 2005;68(4):487-92.
2005: Murphy Brian T; Cao Shugeng; Norris Andrew; Miller James S; Ratovoson Fidisoa; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
Cytotoxic flavanones of Schizolaena hystrix from the Madagascar rainforest.
Journal of natural products 2005;68(3):417-9.
2005: Kingston David G I; Newman David J
The search for novel drug leads for predominately antitumor therapies by utilizing mother nature's pharmacophoric libraries.
Current opinion in drug discovery & development 2005;8(2):207-27.
2005: Cao Shugeng; Foster Caleb; Brisson Marni; Lazo John S; Kingston David G I
Halenaquinone and xestoquinone derivatives, inhibitors of Cdc25B phosphatase from a Xestospongia sp.
Bioorganic & medicinal chemistry 2005;13(4):999-1003.
2005: Kingston David G I; Bane Susan; Snyder James P
The taxol pharmacophore and the T-taxol bridging principle.
Cell cycle (Georgetown, Tex.) 2005;4(2):279-89.
2004: Chaturvedula V S Prakash; Farooq Afgan; Schilling Jennifer K; Malone S; Derveld Iwan; Werkhoven Marga C M; Wisse Jan H; Ratsimbason Michel; Kingston David G I
New eudesmane derivatives from Melampodium camphoratum from the Suriname rainforest.
Journal of natural products 2004;67(12):2053-7.
2004: Chaturvedula V S Prakash; Zhou Bing-Nan; Gao Zhijie; Thomas Shannon J; Hecht Sidney M; Kingston David G I
New lupane triterpenoids from Solidago canadensis that inhibit the lyase activity of DNA polymerase beta.
Bioorganic & medicinal chemistry 2004;12(23):6271-5.
2004: Liu Changhui; Schilling Jennifer K; Ravindra Rudravajhala; Bane Susan; Kingston David G I
Syntheses and bioactivities of macrocyclic paclitaxel bis-lactones.
Bioorganic & medicinal chemistry 2004;12(23):6147-61.
2004: Radwan Mohamed M; El-Sebakhy Nadia A; Asaad Aya M; Toaima Soad M; Kingston David G I
Kahiricosides II-V, cycloartane glycosides from an Egyptian collection of Astragalus kahiricus.
Phytochemistry 2004;65(21):2909-13.
2004: Cao Shugeng; Gao Zhijie; Thomas Shannon J; Hecht Sidney M; Lazo John S; Kingston David G I
Marine sesquiterpenoids that inhibit the lyase activity of DNA polymerase beta.
Journal of natural products 2004;67(10):1716-8.
2004: Cao Shugeng; Schilling Jennifer K; Randrianasolo Armand; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
New cytotoxic alkyl phloroglucinols from Protorhus thouvenotii.
Planta medica 2004;70(7):683-5.
2004: Ganesh Thota; Guza Rebecca C; Bane Susan; Ravindra Rudravajhala; Shanker Natasha; Lakdawala Ami S; Snyder James P; Kingston David G I
The bioactive Taxol conformation on beta-tubulin: experimental evidence from highly active constrained analogs.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(27):10006-11.
2004: Cao Shugeng; Guza Rebecca Clare; Miller James S; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
Cytotoxic triterpenoids from Acridocarpus vivy from the Madagascar rain forest.
Journal of natural products 2004;67(6):986-9.
2004: Prakash Chaturvedula V S; Hecht Sidney M; Gao Zhijie; Jones Shannon H; Feng Xizhi; Kingston David G I
New neolignans that inhibit DNA polymerase beta lyase.
Journal of natural products 2004;67(6):964-7.
2004: Chaturvedula V S Prakash; Gao Zhijie; Jones Shannon H; Feng Xizhi; Hecht Sidney M; Kingston David G I
A new ursane triterpene from Monochaetum vulcanicum that inhibits DNA polymerase beta lyase.
Journal of natural products 2004;67(5):899-901.
2004: Chaturvedula V S Prakash; Schilling Jennifer K; Miller James S; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
New cytotoxic terpenoids from the wood of Vepris punctata from the Madagascar Rainforest.
Journal of natural products 2004;67(5):895-8.
2004: Radwan Mohamed M; Farooq Afgan; El-Sebakhy Nadia A; Asaad Aya M; Toaima Soad M; Kingston David G I
Acetals of three new cycloartane-type saponins from Egyptian collections of Astragalus tomentosus.
Journal of natural products 2004;67(3):487-90.
2004: Cao Shugeng; Schilling Jennifer K; Miller James S; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
Cytotoxic compounds from Mundulea chapelieri from the Madagascar Rainforest.
Journal of natural products 2004;67(3):454-6.
2004: Kingston David G I
What makes epothilones stick?
Chemistry & biology 2004;11(2):153-5.
2004: Liu Changhui; Strobl Jeannine S; Bane Susan; Schilling Jennifer K; McCracken Meredith; Chatterjee Sabarni K; Rahim-Bata Rayhana; Kingston David G I
Design, synthesis, and bioactivities of steroid-linked taxol analogues as potential targeted drugs for prostate and breast cancer.
Journal of natural products 2004;67(2):152-9.
2004: Topçu Gülaçti; Türkmen Zeynep; Ulubelen Ayhan; Schilling Jennifer K; Kingston David G I
Highly hydroxylated triterpenes from Salvia kronenburgii.
Journal of natural products 2004;67(1):118-21.
2003: Topcu Gulaçti; Aydogmus Zeynep; Imre Sedat; Gören Ahmet C; Pezzuto John M; Clement Jason A; Kingston David G I
Brominated sesquiterpenes from the red alga Laurencia obtusa.
Journal of natural products 2003;66(11):1505-8.
2003: Prakash Chaturvedula V S; Gao Zhijie; Hecht Sidney M; Jones Shannon H; Kingston David G I
A new acylated oleanane triterpenoid from Couepia polyandra that inhibits the lyase activity of DNA polymerase beta.
Journal of natural products 2003;66(11):1463-5.
2003: Gören Ahmet C; Zhou Bing-Nan; Kingston David G
Cytotoxic and DNA damaging activity of some aporphine alkaloids from Stephania dinklagei.
Planta medica 2003;69(9):867-8.
2003: Williams Russell B; Hoch Jeannine; Glass Thomas E; Evans Randy; Miller James S; Wisse Jan H; Kingston David G
A novel cytotoxic guttiferone analogue from Garcinia macrophylla from the Suriname rainforest.
Planta medica 2003;69(9):864-6.
2003: Topcu Gulacti; Altiner Esra N; Gozcu Seyda; Halfon Belkis; Aydogmus Zeynep; Pezzuto J M; Zhou Bing-Nan; Kingston David G
Studies on di- and triterpenoids from Salvia staminea with cytotoxic activity.
Planta medica 2003;69(5):464-7.
2003: Chaturvedula V S Prakash; Schilling Jennifer K; Miller James S; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G
New cytotoxic oleanane saponins from the infructescences of Polyscias amplifolia from the Madagascar rainforest.
Planta medica 2003;69(5):440-4.
2003: Prakash Chaturvedula V S; Schilling Jennifer K; Miller James S; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
New cytotoxic alkaloids from the wood of Vepris punctata from the Madagascar rainforest.
Journal of natural products 2003;66(4):532-4.
2003: Prakash Chaturvedula V S; Sprague Shannon; Schilling Jennifer K; Kingston David G I
New cytotoxic indole alkaloids from Tabernaemontana calcarea from the Madagascar rainforest.
Journal of natural products 2003;66(4):528-31.
2003: Barron Donna M; Chatterjee Sabarni K; Ravindra Rudravajhala; Roof Rebecca; Baloglu Erkan; Kingston David G I; Bane Susan
A fluorescence-based high-throughput assay for antimicrotubule drugs.
Analytical biochemistry 2003;315(1):49-56.
2003: Baloglu Erkan; Hoch Jeannine M; Chatterjee Sabarni K; Ravindra Rudravajhala; Bane Susan; Kingston David G I
Synthesis and biological evaluation of C-3'NH/C-10 and C-2/C-10 modified paclitaxel analogues.
Bioorganic & medicinal chemistry 2003;11(7):1557-68.
2003: Chaturvedula V S; Schilling Jennifer K; Malone Stan; Wisse Jan H; Werkhoven Marga C; Kingston David G
New cytotoxic triterpene acids from aboveground parts of Manihot esculenta from the Suriname rainforest.
Planta medica 2003;69(3):271-4.
2003: Prakash Chaturvedula V S; Schilling Jennifer K; Johnson Randall K; Kingston David G I
New cytotoxic lupane triterpenoids from the twigs of Coussarea paniculata.
Journal of natural products 2003;66(3):419-22.
2002: Chaturvedula V S Prakash; Schilling Jennifer K; Miller James S; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
New cytotoxic bis 5-alkylresorcinol derivatives from the leaves of Oncostemon bojerianum from the Madagascar rainforest.
Journal of natural products 2002;65(11):1627-32.
2002: Chaturvedula V S Prakash; Schilling Jennifer K; Miller James S; Andriantsiferana Rabodo; Rasamison Vincent E; Kingston David G I
Two new triterpene esters from the twigs of Brachylaena ramiflora from the Madagascar rainforest.
Journal of natural products 2002;65(8):1222-4.
2002: Jagtap Prakash G; Baloglu Erkan; Barron Donna M; Bane Susan; Kingston David G I
Design and synthesis of a combinatorial chemistry library of 7-acyl, 10-acyl, and 7,10-diacyl analogues of paclitaxel (taxol) using solid phase synthesis.
Journal of natural products 2002;65(8):1136-42.
2002: Chaturvedula V S Prakash; Schilling Jennifer K; Kingston David G I
New cytotoxic coumarins and prenylated benzophenone derivatives from the bark of Ochrocarpos punctatus from the Madagascar rainforest.
Journal of natural products 2002;65(7):965-72.
2002: Abou-Donia Amina H; Amer Masouda E; Darwish Fikria A; Kassem Fahima F; Hammoda Hala M; Abdel-Kader Maged S; Zhou Bing-Nan; Kingston David G I
Two new alkaloids of the crinane series from Pancratium sickenbergeri.
Planta medica 2002;68(4):379-81.
2002: Kingston David G I; Newman David J
Mother nature's combinatorial libraries; their influence on the synthesis of drugs.
Current opinion in drug discovery & development 2002;5(2):304-16.
2002: Seo Youngwan; Hoch Jeannine; Abdel-Kader Maged; Malone S; Derveld I; Adams Hermus; Werkhoven M C M; Wisse Jan H; Mamber Stephen W; Dalton James M; Kingston David G I
Bioactive saponins from Acacia tenuifolia from the suriname rainforest.
Journal of natural products 2002;65(2):170-4.
2002: Sai Prakash Chaturvedula V; Hoch Jeannine M; Kingston David G I
Structure and stereochemistry of new cytotoxic clerodane diterpenoids from the bark of Casearia lucida from the Madagascar rainforest.
Journal of natural products 2002;65(2):100-7.
2002: Seo Youngwan; Berger John M; Hoch Jeannine; Neddermann Kim M; Bursuker Isia; Mamber Steven W; Kingston David G I
A new triterpene saponin from Pittosporum viridiflorum from the Madagascar rainforest.
Journal of natural products 2002;65(1):65-8.
2002: Abdel-Kader Maged; Berger John M; Slebodnick Carla; Hoch Jeannine; Malone Stan; Wisse Jan H; Werkhoven Marga C M; Mamber Steven; Kingston David G I
Isolation and absolute configuration of ent-Halimane diterpenoids from Hymenaea courbaril from the Suriname rain forest.
Journal of natural products 2002;65(1):11-5.
2001: Zhou B N; Johnson R K; Mattern M R; Fisher P W; Kingston D G
The first naturally occurring Tie2 kinase inhibitor.
Organic letters 2001;3(25):4047-9.
2001: Baloglu E; Kingston D G; Patel P; Chatterjee S K; Bane S L
Synthesis and microtubule binding of fluorescent paclitaxel derivatives.
Bioorganic & medicinal chemistry letters 2001;11(17):2249-52.
2001: Metaferia B B; Hoch J; Glass T E; Bane S L; Chatterjee S K; Snyder J P; Lakdawala A; Cornett B; Kingston D G
Synthesis and biological evaluation of novel macrocyclic paclitaxel analogues.
Organic letters 2001;3(16):2461-4.
2001: Abdel-Kader M; Hoch J; Berger J M; Evans R; Miller J S; Wisse J H; Mamber S W; Dalton J M; Kingston D G
Two bioactive saponins from Albizia subdimidiata from the Suriname rainforest.
Journal of natural products 2001;64(4):536-9.
2001: Chordia M D; Yuan H; Jagtap P G; Kadow J F; Long B H; Fairchild C R; Johnston K A; Kingston D G
Synthesis and bioactivity of 2,4-diacyl analogues of paclitaxel.
Bioorganic & medicinal chemistry 2001;9(1):171-8.
2001: Gunatilaka A A; Berger J M; Evans R; Miller J S; Wisse J H; Neddermann K M; Bursuker I; Kingston D G
Isolation, synthesis, and structure-activity relationships of bioactive benzoquinones from Miconia lepidota from the Suriname rainforest.
Journal of natural products 2001;64(1):2-5.
2000: Abdel-Kader M S; Bahler B D; Malone S; Werkhoven M C; Wisse J H; Neddermann K M; Bursuker I; Kingston D G
Bioactive saponins from Swartzia schomburgkii from the suriname rainforest.
Journal of natural products 2000;63(11):1461-4.
2000: Zhou B N; Hoch J M; Johnson R K; Mattern M R; Eng W K; Ma J; Hecht S M; Newman D J; Kingston D G
Use of COMPARE analysis to discover new natural product drugs: isolation of camptothecin and 9-methoxycamptothecin from a new source.
Journal of natural products 2000;63(9):1273-6.
2000: Kingston D G
Recent advances in the chemistry of taxol.
Journal of natural products 2000;63(5):726-34.
2000: Schwikkard S; Zhou B N; Glass T E; Sharp J L; Mattern M R; Johnson R K; Kingston D G
Bioactive compounds from Combretum erythrophyllum.
Journal of natural products 2000;63(4):457-60.
2000: Zhou B N; Johnson R K; Mattern M R; Wang X; Hecht S M; Beck H T; Ortiz A; Kingston D G
Isolation and biochemical characterization of a new topoisomerase I inhibitor from Ocotea leucoxylon.
Journal of natural products 2000;63(2):217-21.
2000: Li Y; Edsall R; Jagtap P G; Kingston D G; Bane S
Equilibrium studies of a fluorescent paclitaxel derivative binding to microtubules.
Biochemistry 2000;39(3):616-23.
2000: Li Y; Poliks B; Cegelski L; Poliks M; Gryczynski Z; Piszczek G; Jagtap P G; Studelska D R; Kingston D G; Schaefer J; Bane S
Conformation of microtubule-bound paclitaxel determined by fluorescence spectroscopy and REDOR NMR.
Biochemistry 2000;39(2):281-91.
1999: Gunatilaka A A; Paul V J; Park P U; Puglisi M P; Gitler A D; Eggleston D S; Haltiwanger R C; Kingston D G
Apakaochtodenes A and B: two tetrahalogenated monoterpenes from the red marine alga Portieria hornemannii.
Journal of natural products 1999;62(10):1376-8.
1999: Yang S W; Zhou B N; Malone S; Werkhoven M C; van Troon F; Wisse J H; Kingston D G
A new labdane diterpenoid from Renealmia alpinia collected in the Suriname rainforest.
Journal of natural products 1999;62(8):1173-4.
1999: Baloglu E; Kingston D G
A new semisynthesis of paclitaxel from baccatin III.
Journal of natural products 1999;62(7):1068-71.
1999: Yang S W; Abdel-Kader M; Malone S; Werkhoven M C; Wisse J H; Bursuker I; Neddermann K; Fairchild C; Raventos-Suarez C; Menendez A T; Lane K; Kingston D G
Synthesis and biological evaluation of analogues of cryptolepine, an alkaloid isolated from the Suriname rainforest.
Journal of natural products 1999;62(7):976-83.
1999: Wu C; Johnson R K; Mattern M R; Wong J C; Kingston D G
Synthesis of furanonaphthoquinones with hydroxyamino side chains.
Journal of natural products 1999;62(7):963-8.
1998: Zhou B N; Bahler B D; Hofmann G A; Mattern M R; Johnson R K; Kingston D G
Phenylethanoid glycosides from Digitalis purpurea and Penstemon linarioides with PKCalpha-inhibitory activity.
Journal of natural products 1998;61(11):1410-2.
1998: Lee K K; Bahler B D; Hofmann G A; Mattern M R; Johnson R K; Kingston D G
Isolation and structure elucidation of new PKCalpha inhibitors from Pinus flexilis.
Journal of natural products 1998;61(11):1407-9.
1998: Abdel-Kader M S; Bahler B D; Malone S; Werkhoven M C; van Troon F; David; Wisse J H; Bursuker I; Neddermann K M; Mamber S W; Kingston D G
DNA-damaging steroidal alkaloids from Eclipta alba from the suriname rainforest1.
Journal of natural products 1998;61(10):1202-8.
1998: Kingston D G; Chaudhary A G; Chordia M D; Gharpure M; Gunatilaka A A; Higgs P I; Rimoldi J M; Samala L; Jagtap P G; Giannakakou P; Jiang Y Q; Lin C M; Hamel E; Long B H; Fairchild C R; Johnston K A
Synthesis and biological evaluation of 2-acyl analogues of paclitaxel (Taxol).
Journal of medicinal chemistry 1998;41(19):3715-26.
1998: Yang S W; Zhou B N; Wisse J H; Evans R; van der Werff H; Miller J S; Kingston D G
Three new ellagic acid derivatives from the bark of Eschweilera coriacea from the Suriname rainforest.
Journal of natural products 1998;61(7):901-6.
1998: Han Y; Malak H; Chaudhary A G; Chordia M D; Kingston D G; Bane S
Distances between the paclitaxel, colchicine, and exchangeable GTP binding sites on tubulin.
Biochemistry 1998;37(19):6636-44.
1998: Gunatilaka A A; Bolzani V da S; Dagne E; Hofmann G A; Johnson R K; McCabe F L; Mattern M R; Kingston D G
Limonoids showing selective toxicity to DNA repair-deficient yeast and other constituents of Trichilia emetica.
Journal of natural products 1998;61(2):179-84.
1997: Wu C; Gunatilaka A A; McCabe F L; Johnson R K; Spjut R W; Kingston D G
Bioactive and other sesquiterpenes from Chiloscyphus rivularis.
Journal of natural products 1997;60(12):1281-6.
1997: Abdel-Kader M S; Wisse J; Evans R; van der Werff H; Kingston D G
Bioactive iridoids and a new lignan from Allamanda cathartica and Himatanthus fallax from the Suriname rainforest.
Journal of natural products 1997;60(12):1294-7.
1997: Zhou B N; Baj N J; Glass T E; Malone S; Werkhoven M C; van Troon F; David; Wisse J H; Kingston D G
Bioactive labdane diterpenoids from Renealmia alpinia collected in the Suriname rainforest.
Journal of natural products 1997;60(12):1287-93.
1997: Chordia M D; Kingston D G; Hamel E; Lin C M; Long B H; Fairchild C A; Johnston K A; Rose W C
Synthesis and biological activity of A-nor-paclitaxel analogues.
Bioorganic & medicinal chemistry 1997;5(5):941-7.
1997: Valente L M; Gunatilaka A A; Kingston D G; Patitucci M L; Pinto A C
A bioactive seco-rosane diterpenoid from Vellozia candida.
Journal of natural products 1997;60(5):478-81.
1996: Phillips W R; Baj N J; Gunatilaka A A; Kingston D G
C-geranyl compounds from Mimulus clevelandii.
Journal of natural products 1996;59(5):495-7.
1996: Kim Y C; Che Q M; Gunatilaka A A; Kingston D G
Bioactive steroidal alkaloids from Solanum umbelliferum.
Journal of natural products 1996;59(3):283-5.
1996: Kim Y C; da S Bolzani V; Baj N; Gunatilaka A A; Kingston D G
A DNA-damaging sesquiterpene and other constituents from Frullania nisquallensis.
Planta medica 1996;62(1):61-3.
1995: Rao S; Orr G A; Chaudhary A G; Kingston D G; Horwitz S B
Characterization of the taxol binding site on the microtubule. 2-(m-Azidobenzoyl)taxol photolabels a peptide (amino acids 217-231) of beta-tubulin.
The Journal of biological chemistry 1995;270(35):20235-8.
1995: Weisburger J H; Rivenson A; Kingston D G; Wilkins T D; Van Tassell R L; Nagao M; Sugimura T; Hara Y
Dietary modulation of the carcinogenicity of the heterocyclic amines.
Princess Takamatsu symposia 1995;23():240-50.
1994: Valente L M; Gunatilaka A A; Kingston D G; Pinto A C
Norcucurbitacin gentiobiosides from Fevillea trilobata.
Journal of natural products 1994;57(11):1560-3.
1994: Chen R; Kingston D G
Isolation and structure elucidation of new taxoids from Taxus brevifolia.
Journal of natural products 1994;57(7):1017-21.
1994: Heltzel C E; Gunatilaka A A; Kingston D G; Hofmann G A; Johnson R K
Synthesis and structure-activity relationships of cytotoxic 7-hydroxy sterols.
Journal of natural products 1994;57(5):620-8.
1994: Gunatilaka A A; Kingston D G; Wijeratne E M; Bandara B M; Hofmann G A; Johnson R K
Biological activity of some coumarins from Sri Lankan Rutaceae.
Journal of natural products 1994;57(4):518-20.
1994: Weisburger J H; Rivenson A; Reinhardt J; Aliaga C; Braley J; Dolan L M; Williams G M; Zang E; Kingston D G; Bashir M
Genotoxicity and carcinogenicity in rats and mice of 2-amino-3,6-dihydro-3-methyl-7H-imidazolo[4,5-f]quinolin-7- one: an intestinal bacterial metabolite of 2-amino-3-methyl-3H-imidazo[4,5-f]quinoline.
Journal of the National Cancer Institute 1994;86(1):25-30.
1994: Harrigan G G; Gunatilaka A A; Kingston D G; Chan G W; Johnson R K
Isolation of bioactive and other oxoaporphine alkaloids from two annonaceous plants, Xylopia aethiopica and Miliusa cf. banacea.
Journal of natural products 1994;57(1):68-73.
1993: Dagne E; Gunatilaka A A; Kingston D G; Alemu M
4'-O-methylstephavanine from Stephania abyssinica.
Journal of natural products 1993;56(11):2022-5.
1993: Dagne E; Gunatilaka A A; Kingston D G; Alemu M; Hofmann G; Johnson R K
Two bioactive pterocarpans from Erythrina burana.
Journal of natural products 1993;56(10):1831-4.
1993: Valente L M; Gunatilaka A A; Glass T E; Kingston D G; Pinto A C
New norcucurbitacin and heptanorcucurbitacin glucosides from Fevillea trilobata.
Journal of natural products 1993;56(10):1772-8.
1993: Hetzel C E; Gunatilaka A A; Glass T E; Kingston D G; Hoffmann G; Johnson R K
Bioactive furanonaphthoquinones from Crescentia cujete.
Journal of natural products 1993;56(9):1500-5.
1993: Rimoldi J M; Kingston D G; Chaudhary A G; Samaranayake G; Grover S; Hamel E
Modified taxols, 9. Synthesis and biological evaluation of 7-substituted photoaffinity analogues of taxol.
Journal of natural products 1993;56(8):1313-30.
1993: Harrigan G G; Ahmad A; Baj N; Glass T E; Gunatilaka A A; Kingston D G
Bioactive and other sesquiterpenoids from Porella cordeana.
Journal of natural products 1993;56(6):921-5.
1993: Samaranayake G; Neidigh K A; Kingston D G
Modified taxols, 8. Deacylation and reacylation of baccatin III.
Journal of natural products 1993;56(6):884-98.
1993: Liang J; Kingston D G
Two new taxane diterpenoids from Taxus mairei.
Journal of natural products 1993;56(4):594-9.
1993: Kingston D G; Molinero A A; Rimoldi J M
The taxane diterpenoids.
Fortschritte der Chemie organischer Naturstoffe. Progress in the chemistry of organic natural products. Progrès dans la chimie des substances organiques naturelles 1993;61():1-206.
1992: Gunatilaka A A; Samaranayake G; Kingston D G; Hoffmann G; Johnson R K
Bioactive ergost-5-ene-3 beta, 7 alpha-diol derivatives from Pseudobersama mossambicensis.
Journal of natural products 1992;55(11):1648-54.
1992: Kingston D G; Gunatilaka A A; Ivey C A
Modified taxols, 7. A method for the separation of taxol and cephalomannine.
Journal of natural products 1992;55(2):259-61.
1991: Shu Y Z; Kingston D G; Van Tassell R L; Wilkins T D
Metabolism of levamisole, an anti-colon cancer drug, by human intestinal bacteria.
Xenobiotica; the fate of foreign compounds in biological systems 1991;21(6):737-50.
1991: Shu Y Z; Kingston D G; Van Tassell R L; Wilkins T D
Metabolism of 1,4-dinitro-2-methylpyrrole, a mutagen formed by a sorbic acid-nitrite reaction, by intestinal bacteria.
Environmental and molecular mutagenesis 1991;17(3):181-7.
1990: Kingston D G; Van Tassell R L; Wilkins T D
The fecapentaenes, potent mutagens from human feces.
Chemical research in toxicology 1990;3(5):391-400.
1990: Van Tassell R L; Kingston D G; Wilkins T D
Metabolism of dietary genotoxins by the human colonic microflora; the fecapentaenes and heterocyclic amines.
Mutation research 1990;238(3):209-21.
1990: Weisburger J H; Jones R C; Wang C X; Backlund J Y; Williams G M; Kingston D G; Van Tassell R L; Keyes R F; Wilkins T D; de Wit P P
Carcinogenicity tests of fecapentaene-12 in mice and rats.
Cancer letters 1990;49(2):89-98.
1990: Van Tassell R L; Kingston D G; Wilkins T D
Dietary genotoxins and the human colonic microflora.
Progress in clinical and biological research 1990;340E():149-58.
1989: Pullockaran A J; Kingston D G; Lewis N G
Synthesis of stereospecifically deuterated desoxypodophyllotoxins and 1H-nmr assignment of desoxypodophyllotoxin.
Journal of natural products 1989;52(6):1290-5.
1989: Van Tassell R L; Piccariello T; Kingston D G; Wilkins T D
The precursors of fecapentaenes: purification and properties of a novel plasmalogen.
Lipids 1989;24(5):454-9.
1988: Carman R J; Van Tassell R L; Kingston D G; Bashir M; Wilkins T D
Conversion of IQ, a dietary pyrolysis carcinogen to a direct-acting mutagen by normal intestinal bacteria of humans.
Mutation research 1988;206(3):335-42.
1988: Magri N F; Kingston D G
Modified taxols, 4. Synthesis and biological activity of taxols modified in the side chain.
Journal of natural products 1988;51(2):298-306.
1988: Kingston D G; Piccariello T; Duh C Y; Govindan S V; Wilkins T D; van Tassell R L; Van der Gen A; De Wit P P; Van der Steeg M
On the stereochemistry of fecapentaene-12.
Journal of natural products 1988;51(1):176-9.
1987: Bashir M; Kingston D G; Carman R J; van Tassell R L; Wilkins T D
Anaerobic metabolism of 2-amino-3-methyl-3H-imidazo[4,5-f]quinoline (IQ) by human fecal flora.
Mutation research 1987;190(3):187-90.
1987: Govindan S V; Kingston D G; Gunatilaka A A; van Tassell R L; Wilkins T D; de Wit P P; van der Steeg M; van der Gen A
Synthesis and biological activity of analogs of fecapentaene-12.
Journal of natural products 1987;50(1):75-83.
1986: Huang C H; Kingston D G; Magri N F; Samaranayake G; Boettner F E
New taxanes from Taxus brevifolia, 2.
Journal of natural products 1986;49(4):665-9.
1985: Hirai N; Kingston D G; Van Tassell R L; Wilkins T D
Isolation and structure elucidation of fecapentaenes-12, potent mutagens from human feces.
Journal of natural products 1985;48(4):622-30.

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