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Paavo Kinnunen

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Paavo K J Kinnunen; Kai Kaarniranta; Ajay K Mahalka
Protein-oxidized phospholipid interactions in cellular signaling for cell death: From biophysics to clinical correlations.
Roberto Tejera-Garcia; Walter A Shaw; Lisa Connell; Paavo K J Kinnunen
Gravimetric determination of phospholipid concentration.
Roman Volinsky; Riku Paananen; Paavo K J Kinnunen
Oxidized phosphatidylcholines promote phase separation of cholesterol-sphingomyelin domains.

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All Publications

2012: Paavo K J Kinnunen; Kai Kaarniranta; Ajay K Mahalka
Protein-oxidized phospholipid interactions in cellular signaling for cell death: From biophysics to clinical correlations.
Biochimica et biophysica acta 2012;1818(10):2446-55.
2012: Roberto Tejera-Garcia; Walter A Shaw; Lisa Connell; Paavo K J Kinnunen
Gravimetric determination of phospholipid concentration.
Chemistry and physics of lipids 2012;165(6):689-95.
2012: Roman Volinsky; Riku Paananen; Paavo K J Kinnunen
Oxidized phosphatidylcholines promote phase separation of cholesterol-sphingomyelin domains.
Biophysical journal 2012;103(2):247-54.
2012: Jing Zou; Dennis Poe; Ilmari Pyykkö; Usama Abo Ramadan; Sanjeev Ranjan; Rohit Sood; Paavo K J Kinnunen
Size-dependent passage of liposome nanocarriers with preserved posttransport integrity across the middle-inner ear barriers in rats.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2012;33(4):666-73.
2011: Ajay K Mahalka; Behnam Rezaijahromi; Christian Code; Marja Jäättelä; Thomas Kirkegaard; Paavo K J Kinnunen
Activation of phospholipase A2 by Hsp70 in vitro.
Biochimica et biophysica acta 2011;1808(10):2569-72.
2011: Roman Volinsky; Lukasz Cwiklik; Martin Hof; Pavel Jungwirth; Piotr Jurkiewicz; Paavo K J Kinnunen
Oxidized phosphatidylcholines facilitate phospholipid flip-flop in liposomes.
Biophysical journal 2011;101(6):1376-84.
2011: Roberto Tejera-Garcia; Vladimir Zamotin; Sanjeev Ranjan; Rohit Sood; Paavo K J Kinnunen
Making unilamellar liposomes using focused ultrasound.
Langmuir : the ACS journal of surfaces and colloids 2011;27(16):10088-97.
2011: Ajay K Mahalka; C Peter J Maury; Paavo K J Kinnunen
1-Palmitoyl-2-(9'-oxononanoyl)-sn-glycero-3-phosphocholine, an oxidized phospholipid, accelerates Finnish type familial gelsolin amyloidosis in vitro.
Biochemistry 2011;50(22):4877-89.
2011: Weikai Zhang; Ya Zhang; Rohit Sood; Sanjeev Ranjan; Elena Surovtseva; Aqeel Ahmad; Paavo K J Kinnunen; Ilmari Pyykkö; Jing Zou
Visualization of intracellular trafficking of Math1 protein in different cell types with a newly-constructed nonviral gene delivery plasmid.
The journal of gene medicine 2011;13(2):134-44.
2010: Valeriya M Trusova; Galyna P Gorbenko; Julian G Molotkovsky; Paavo K J Kinnunen
Cytochrome c-lipid interactions: new insights from resonance energy transfer.
Biophysical journal 2010;99(6):1754-63.
2010: Marcelo B D Borges; Carolina G Dos Santos; César H Yokomizo; Rohit Sood; Pavol Vitovic; Paavo K J Kinnunen; Tiago Rodrigues; Iseli L Nantes
Characterization of hydrophobic interaction and antioxidant properties of the phenothiazine nucleus in mitochondrial and model membranes.
Free radical research 2010;44(9):1054-63.
2010: Christian Code; Ajay K Mahalka; Kristian Bry; Paavo K J Kinnunen
Activation of phospholipase A2 by 1-palmitoyl-2-(9'-oxo-nonanoyl)-sn-glycero-3-phosphocholine in vitro.
Biochimica et biophysica acta 2010;1798(8):1593-600.
2010: Juha-Matti Alakoskela; Mikko J Parry; Paavo K J Kinnunen
The intermediate state of DMPG is stabilized by enhanced positive spontaneous curvature.
Langmuir : the ACS journal of surfaces and colloids 2010;26(7):4892-900.
2010: Mikko J Parry; Morten Hagen; Ole G Mouritsen; Paavo K J Kinnunen; Juha-Matti Alakoskela
Interlamellar coupling of phospholipid bilayers in liposomes: an emergent property of lipid rearrangement.
Langmuir : the ACS journal of surfaces and colloids 2010;26(7):4909-15.
2010: Thomas Kirkegaard; Anke G Roth; Nikolaj H T Petersen; Ajay K Mahalka; Ole Dines Olsen; Irina Moilanen; Alicja Zylicz; Jens Knudsen; Konrad Sandhoff; Christoph Arenz; Paavo K J Kinnunen; Jesper Nylandsted; Marja Jäättelä
Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.
Nature 2010;463(7280):549-53.
2009: Juha-Matti Alakoskela; Pavol Vitovic; Paavo K J Kinnunen
Screening for the drug-phospholipid interaction: correlation to phospholipidosis.
ChemMedChem 2009;4(8):1224-51.
2009: Ajay K Mahalka; Paavo K J Kinnunen
Binding of amphipathic alpha-helical antimicrobial peptides to lipid membranes: lessons from temporins B and L.
Biochimica et biophysica acta 2009;1788(8):1600-9.
2009: Galyna P Gorbenko; Valeriya M Trusova; Julian G Molotkovsky; Paavo K J Kinnunen
Cytochrome c induces lipid demixing in weakly charged phosphatidylcholine/phosphatidylglycerol model membranes as evidenced by resonance energy transfer.
Biochimica et biophysica acta 2009;1788(6):1358-65.
2009: Christian Code; Yegor A Domanov; J Antoinette Killian; Paavo K J Kinnunen
Activation of phospholipase A2 by temporin B: formation of antimicrobial peptide-enzyme amyloid-type cofibrils.
Biochimica et biophysica acta 2009;1788(5):1064-72.
2009: Juha Saarikangas; Hongxia Zhao; Anette Pykäläinen; Pasi Laurinmäki; Pieta K Mattila; Paavo K J Kinnunen; Sarah J Butcher; Pekka Lappalainen
Molecular mechanisms of membrane deformation by I-BAR domain proteins.
Current biology : CB 2009;19(2):95-107.
2008: Jaime Guillén; Paavo K J Kinnunen; José Villalaín
Membrane insertion of the three main membranotropic sequences from SARS-CoV S2 glycoprotein.
Biochimica et biophysica acta 2008;1778(12):2765-74.
2008: Mikko J Parry; Juha-Matti Alakoskela; Himanshu Khandelia; Subramanian Arun Kumar; Marja Jäättelä; Ajay K Mahalka; Paavo K J Kinnunen
High-affinity small molecule-phospholipid complex formation: binding of siramesine to phosphatidic acid.
Journal of the American Chemical Society 2008;130(39):12953-60.
2008: Juha-Pekka Mattila; Karen Sabatini; Paavo K J Kinnunen
Oxidized phospholipids as potential molecular targets for antimicrobial peptides.
Biochimica et biophysica acta 2008;1778(10):2041-50.
2008: Karen Sabatini; Juha-Pekka Mattila; Paavo K J Kinnunen
Interfacial behavior of cholesterol, ergosterol, and lanosterol in mixtures with DPPC and DMPC.
Biophysical journal 2008;95(5):2340-55.
2008: Christian Code; Yegor Domanov; Arimatti Jutila; Paavo K J Kinnunen
Amyloid-type fiber formation in control of enzyme action: interfacial activation of phospholipase A2.
Biophysical journal 2008;95(1):215-24.
2008: Rohit Sood; Paavo K J Kinnunen
Cholesterol, lanosterol, and ergosterol attenuate the membrane association of LL-37(W27F) and temporin L.
Biochimica et biophysica acta 2008;1778(6):1460-6.
2008: Pablo V Escribá; José M González-Ros; Félix M Goñi; Paavo K J Kinnunen; Lászlo Vigh; Lissete Sánchez-Magraner; Asia M Fernández; Xavier Busquets; Ibolya Horváth; Gwendolyn Barceló-Coblijn
Membranes: a meeting point for lipids, proteins and therapies.
Journal of cellular and molecular medicine 2008;12(3):829-75.
2008: Galyna P Gorbenko; Valeriya M Ioffe; Julian G Molotkovsky; Paavo K J Kinnunen
Resonance energy transfer study of lysozyme-lipid interactions.
Biochimica et biophysica acta 2008;1778(5):1213-21.
2008: Juha-Pekka Mattila; Karen Sabatini; Paavo K J Kinnunen
Interaction of cytochrome c with 1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine: evidence for acyl chain reversal.
Langmuir : the ACS journal of surfaces and colloids 2008;24(8):4157-60.
2008: Rohit Sood; Yegor Domanov; Milla Pietiäinen; Vesa P Kontinen; Paavo K J Kinnunen
Binding of LL-37 to model biomembranes: insight into target vs host cell recognition.
Biochimica et biophysica acta 2008;1778(4):983-96.
2008: Pavol Vitovic; Juha-Matti Alakoskela; Paavo K J Kinnunen
Assessment of drug-lipid complex formation by a high-throughput Langmuir-balance and correlation to phospholipidosis.
Journal of medicinal chemistry 2008;51(6):1842-8.
2008: Yegor A Domanov; Paavo K J Kinnunen
Islet amyloid polypeptide forms rigid lipid-protein amyloid fibrils on supported phospholipid bilayers.
Journal of molecular biology 2008;376(1):42-54.
2008: Juha-Matti Alakoskela; Karen Sabatini; Xin Jiang; Venla Laitala; Douglas F Covey; Paavo K J Kinnunen
Enantiospecific interactions between cholesterol and phospholipids.
Langmuir : the ACS journal of surfaces and colloids 2008;24(3):830-6.
2007: Juha-Pekka Mattila; Karen Sabatini; Paavo K J Kinnunen
Oxidized phospholipids as potential novel drug targets.
Biophysical journal 2007;93(9):3105-12.
2007: Galyna P Gorbenko; Valeriya M Ioffe; Paavo K J Kinnunen
Binding of lysozyme to phospholipid bilayers: evidence for protein aggregation upon membrane association.
Biophysical journal 2007;93(1):140-53.
2007: Paola Luciani; Cecilia Bombelli; Marisa Colone; Luisa Giansanti; Samppa J Ryhänen; V Matti J Säily; Giovanna Mancini; Paavo K J Kinnunen
Influence of the spacer of cationic gemini amphiphiles on the hydration of lipoplexes.
Biomacromolecules 2007;8(6):1999-2003.
2007: Juha-Matti Alakoskela; Paavo K J Kinnunen
Thermal phase behavior of DMPG: the exclusion of continuous network and dense aggregates.
Langmuir : the ACS journal of surfaces and colloids 2007;23(8):4203-13.
2007: Rohit Sood; Yegor Domanov; Paavo K J Kinnunen
Fluorescent temporin B derivative and its binding to liposomes.
Journal of fluorescence 2007;17(2):223-34.
2007: Niko L Setälä; Juha M Holopainen; Jari Metso; Susanne K Wiedmer; Gebrenegus Yohannes; Paavo K J Kinnunen; Christian Ehnholm; Matti Jauhiainen
Interfacial and lipid transfer properties of human phospholipid transfer protein: implications for the transfer mechanism of phospholipids.
Biochemistry 2007;46(5):1312-9.
2007: Valeriya M Ioffe; Galyna P Gorbenko; Paavo K J Kinnunen; Anatoliy L Tatarets; Olga S Kolosova; Leonid D Patsenker; E Terpetschnig
Tracing lysozyme-lipid interactions with long-wavelength squaraine dyes.
Journal of fluorescence 2007;17(1):65-72.
2007: Mikko J Parry; Arimatti Jutila; Paavo K J Kinnunen; Juha-Matti Alakoskela
A versatile method for determining the molar ligand-membrane partition coefficient.
Journal of fluorescence 2007;17(1):97-103.
2007: Juha-Matti Alakoskela; Douglas F Covey; Paavo K J Kinnunen
Lack of enantiomeric specificity in the effects of anesthetic steroids on lipid bilayers.
Biochimica et biophysica acta 2007;1768(1):131-45.
2006: Yegor A Domanov; Paavo K J Kinnunen
Antimicrobial peptides temporins B and L induce formation of tubular lipid protrusions from supported phospholipid bilayers.
Biophysical journal 2006;91(12):4427-39.
2006: Juha-Matti Alakoskela; Arimatti Jutila; Adam Cohen Simonsen; Jussi Pirneskoski; Sinikka Pyhäjoki; Raija Turunen; Sani Marttila; Ole G Mouritsen; Erik Goormaghtigh; Paavo K J Kinnunen
Characteristics of fibers formed by cytochrome c and induced by anionic phospholipids.
Biochemistry 2006;45(45):13447-53.
2006: Hongxia Zhao; Rohit Sood; Arimatti Jutila; Shambhunath Bose; Gunnar Fimland; Jon Nissen-Meyer; Paavo K J Kinnunen
Interaction of the antimicrobial peptide pheromone Plantaricin A with model membranes: implications for a novel mechanism of action.
Biochimica et biophysica acta 2006;1758(9):1461-74.
2006: Emma Falck; Jari T Hautala; mikko karttunen; Paavo K J Kinnunen; Michael Patra; Heikki Saaren-Seppälä; Ilpo Vattulainen; Susanne K Wiedmer; Juha M Holopainen
Interaction of fusidic acid with lipid membranes: Implications to the mechanism of antibiotic activity.
Biophysical journal 2006;91(5):1787-99.
2006: Samppa J Ryhänen; V Matti J Säily; Paavo K J Kinnunen
Cationic lipid membranes-specific interactions with counter-ions.
Journal of physics. Condensed matter : an Institute of Physics journal 2006;18(28):S1139-50.
2006: Samppa J Ryhänen; V Matti J Säily; Mikko J Parry; Paola Luciani; Giovanna Mancini; Juha-Matti Alakoskela; Paavo K J Kinnunen
Counterion-controlled transition of a cationic gemini from submicroscopic to giant vesicles.
Journal of the American Chemical Society 2006;128(26):8659-63.
2006: Karen Sabatini; Juha-Pekka Mattila; Francesco M Megli; Paavo K J Kinnunen
Characterization of two oxidatively modified phospholipids in mixed monolayers with DPPC.
Biophysical journal 2006;90(12):4488-99.
2006: Gunnar Fimland; Jussi Pirneskoski; Jasadee Kaewsrichan; Arimatti Jutila; Per Eugen Kristiansen; Paavo K J Kinnunen; Jon Nissen-Meyer
Mutational analysis and membrane-interactions of the beta-sheet-like N-terminal domain of the pediocin-like antimicrobial peptide sakacin P.
Biochimica et biophysica acta 2006;1764(6):1132-40.
2006: Galyna P Gorbenko; Paavo K J Kinnunen
The role of lipid-protein interactions in amyloid-type protein fibril formation.
Chemistry and physics of lipids 2006;141(1-2):72-82.
2006: Galyna P Gorbenko; Julian G Molotkovsky; Paavo K J Kinnunen
Cytochrome C interaction with cardiolipin/phosphatidylcholine model membranes: effect of cardiolipin protonation.
Biophysical journal 2006;90(11):4093-103.
2006: Wenjun Li; Douglas F Covey; Juha-Matti Alakoskela; Paavo K J Kinnunen; Joe Henry Steinbach
Enantiomers of neuroactive steroids support a specific interaction with the GABA-C receptor as the mechanism of steroid action.
Molecular pharmacology 2006;69(6):1779-82.
2006: V Matti J Säily; Samppa J Ryhänen; Hilkka Lankinen; Paola Luciani; Giovanna Mancini; Mikko J Parry; Paavo K J Kinnunen
Impact of reductive cleavage of an intramolecular disulfide bond containing cationic gemini surfactant in monolayers and bilayers.
Langmuir : the ACS journal of surfaces and colloids 2006;22(3):956-62.
2005: Heikki Saaren-Seppälä; Matti Jauhiainen; Timo M T Tervo; Bernhard Redl; Paavo K J Kinnunen; Juha M Holopainen
Interaction of purified tear lipocalin with lipid membranes.
Investigative ophthalmology & visual science 2005;46(10):3649-56.
2005: Antti J Metso; Hongxia Zhao; Ilkka Tuunainen; Paavo K J Kinnunen
Observation of the main phase transition of dinervonoylphosphocholine giant liposomes by fluorescence microscopy.
Biochimica et biophysica acta 2005;1713(2):83-91.
2005: Samppa J Ryhänen; Juha-Matti Alakoskela; Paavo K J Kinnunen
Increasing surface charge density induces interdigitation in vesicles of cationic amphiphile and phosphatidylcholine.
Langmuir : the ACS journal of surfaces and colloids 2005;21(13):5707-15.
2005: Milena Johans; Eva Milanesi; Marina Franck; Christoffer Johans; Julius Liobikas; Maria Panagiotaki; Lucedio Greci; Giovanni Principato; Paavo K J Kinnunen; Paolo Bernardi; Paola Costantini; Ove Eriksson
Modification of permeability transition pore arginine(s) by phenylglyoxal derivatives in isolated mitochondria and mammalian cells. Structure-function relationship of arginine ligands.
The Journal of biological chemistry 2005;280(13):12130-6.
2005: Hongxia Zhao; Arimatti Jutila; Tuula A Nurminen; Sara A Wickström; Jorma Keski-Oja; Paavo K J Kinnunen
Binding of endostatin to phosphatidylserine-containing membranes and formation of amyloid-like fibers.
Biochemistry 2005;44(8):2857-63.
2005: Oula Penate Medina; Kalevi Kairemo; Heli Valtanen; Aino Kangasniemi; Sami Kaukinen; Ilona Ahonen; Perttu Permi; Arto Annila; Mia Sneck; Juha M Holopainen; Sirkka-Liisa Karonen; Paavo K J Kinnunen; Erkki Koivunen
Radionuclide imaging of tumor xenografts in mice using a gelatinase-targeting peptide.
Anticancer research 2005;25(1A):33-42.
2005: Juha M Holopainen; Tim Söderlund; Juha-Matti Alakoskela; Matti J Säily; Ove Eriksson; Paavo K J Kinnunen
Intermolecular interactions of lysobisphosphatidic acid with phosphatidylcholine in mixed bilayers.
Chemistry and physics of lipids 2005;133(1):51-67.
2004: Gebrenegus Yohannes; Susanne K Wiedmer; Esa K J Tuominen; Paavo K J Kinnunen; Marja-Liisa Riekkola
Cytochrome c-dimyristoylphosphatidylglycerol interactions studied by asymmetrical flow field-flow fractionation.
Analytical and bioanalytical chemistry 2004;380(5-6):757-66.
2004: Arimatti Jutila; Keng Zhu; Esa K J Tuominen; Paavo K J Kinnunen
Fluorescence spectroscopic characterization of Humicola lanuginosa lipase dissolved in its substrate.
Biochimica et biophysica acta 2004;1702(2):181-9.
2004: Hongxia Zhao; Esa K J Tuominen; Paavo K J Kinnunen
Formation of amyloid fibers triggered by phosphatidylserine-containing membranes.
Biochemistry 2004;43(32):10302-7.
2004: Shambhunath Bose; Ilkka Tuunainen; Mikko Parry; Oula Penate Medina; Giovanna Mancini; Paavo K J Kinnunen
Binding of cationic liposomes to apoptotic cells.
Analytical biochemistry 2004;331(2):385-94.
2004: Hongxia Zhao; Shambhunath Bose; Esa K J Tuominen; Paavo K J Kinnunen
Interactions of histone H1 with phospholipids and comparison of its binding to giant liposomes and human leukemic T cells.
Biochemistry 2004;43(31):10192-202.
2004: Juha-Matti Alakoskela; Tim Söderlund; Juha M Holopainen; Paavo K J Kinnunen
Dipole potential and head-group spacing are determinants for the membrane partitioning of pregnanolone.
Molecular pharmacology 2004;66(1):161-8.
2004: Antti J Metso; Juha-Pekka Mattila; Paavo K J Kinnunen
Characterization of the main transition of dinervonoylphosphocholine liposomes by fluorescence spectroscopy.
Biochimica et biophysica acta 2004;1663(1-2):222-31.
2004: Pekka Suomalainen; Christoffer Johans; Tim Söderlund; Paavo K J Kinnunen
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Journal of medicinal chemistry 2004;47(7):1783-8.
2004: Juha M Holopainen; Antti J Metso; Juha-Pekka Mattila; Arimatti Jutila; Paavo K J Kinnunen
Evidence for the lack of a specific interaction between cholesterol and sphingomyelin.
Biophysical journal 2004;86(3):1510-20.
2003: Tim Söderlund; Juha-Matti Alakoskela; Antti L Pakkanen; Paavo K J Kinnunen
Comparison of the effects of surface tension and osmotic pressure on the interfacial hydration of a fluid phospholipid bilayer.
Biophysical journal 2003;85(4):2333-41.
2003: Oliver Speer; Sarune Morkunaite-Haimi; Julius Liobikas; Marina Franck; Linn Hensbo; Matts D Linder; Paavo K J Kinnunen; Theo Wallimann; Ove Eriksson
Rapid suppression of mitochondrial permeability transition by methylglyoxal. Role of reversible arginine modification.
The Journal of biological chemistry 2003;278(37):34757-63.
2003: Jari T Hautala; Maria V Lindén; Susanne K Wiedmer; Samppa J Ryhänen; Matti J Säily; Paavo K J Kinnunen; Marja-Liisa Riekkola
Simple coating of capillaries with anionic liposomes in capillary electrophoresis.
Journal of chromatography. A 2003;1004(1-2):81-90.
2003: Hongxia Zhao; Paavo K J Kinnunen
Modulation of the activity of secretory phospholipase A2 by antimicrobial peptides.
Antimicrobial agents and chemotherapy 2003;47(3):965-71.
2003: Juha M Holopainen; Miglena I Angelova; Paavo K J Kinnunen
Giant liposomes in studies on membrane domain formation.
Methods in enzymology 2003;367():15-23.
2003: Samppa J Ryhänen; Matti J Säily; Tommi Paukku; Stefano Borocci; Giovanna Mancini; Juha M Holopainen; Paavo K J Kinnunen
Surface charge density determines the efficiency of cationic gemini surfactant based lipofection.
Biophysical journal 2003;84(1):578-87.
2002: Andrea C Rinaldi; Maria Luisa Mangoni; Anna Rufo; Carla Luzi; Donatella Barra; Hongxia Zhao; Paavo K J Kinnunen; Argante Bozzi; Antonio Di Giulio; Maurizio Simmaco
Temporin L: antimicrobial, haemolytic and cytotoxic activities, and effects on membrane permeabilization in lipid vesicles.
The Biochemical journal 2002;368(Pt 1):91-100.
2002: Tuula A Nurminen; Juha M Holopainen; Hongxia Zhao; Paavo K J Kinnunen
Observation of topical catalysis by sphingomyelinase coupled to microspheres.
Journal of the American Chemical Society 2002;124(41):12129-34.
2002: Hongxia Zhao; Patricia M Dubielecka; Tim Söderlund; Paavo K J Kinnunen
Interactions of adriamycin, cytochrome c, and serum albumin with lipid monolayers containing poly(ethylene glycol)-ceramide.
Biophysical journal 2002;83(2):954-67.
2002: Juha M Holopainen; Miglena I Angelova; Tim Söderlund; Paavo K J Kinnunen
Macroscopic consequences of the action of phospholipase C on giant unilamellar liposomes.
Biophysical journal 2002;83(2):932-43.
2002: Hongxia Zhao; Paavo K J Kinnunen
Binding of the antimicrobial peptide temporin L to liposomes assessed by Trp fluorescence.
The Journal of biological chemistry 2002;277(28):25170-7.
2002: Hongxia Zhao; Andrea C Rinaldi; Antonio Di Giulio; Maurizio Simmaco; Paavo K J Kinnunen
Interactions of the antimicrobial peptides temporins with model biomembranes. Comparison of temporins B and L.
Biochemistry 2002;41(13):4425-36.
2002: Esa K J Tuominen; Carmichael J A Wallace; Paavo K J Kinnunen
Phospholipid-cytochrome c interaction: evidence for the extended lipid anchorage.
The Journal of biological chemistry 2002;277(11):8822-6.
2002: Matts D Linder; Sarune Morkunaite-Haimi; Paavo K J Kinnunen; Paolo Bernardi; Ove Eriksson
Ligand-selective modulation of the permeability transition pore by arginine modification. Opposing effects of p-hydroxyphenylglyoxal and phenylglyoxal.
The Journal of biological chemistry 2002;277(2):937-42.
2002: mikko karttunen; Antti L Pakkanen; Paavo K J Kinnunen; Kimmo Kaski
Computational modeling of DNA-cationic lipid complexation.
Cellular & molecular biology letters 2002;7(2):238-9.
2002: Paavo K J Kinnunen; Juha M Holopainen
Sphingomyelinase activity of LDL: a link between atherosclerosis, ceramide, and apoptosis?
Trends in cardiovascular medicine 2002;12(1):37-42.
2001: Hongxia Zhao; Juha-Pekka Mattila; Juha M Holopainen; Paavo K J Kinnunen
Comparison of the membrane association of two antimicrobial peptides, magainin 2 and indolicidin.
Biophysical journal 2001;81(5):2979-91.
2001: V Matti; J Säily; Samppa J Ryhänen; Juha M Holopainen; Stefano Borocci; Giovanna Mancini; Paavo K J Kinnunen
Characterization of mixed monolayers of phosphatidylcholine and a dicationic gemini surfactant SS-1 with a langmuir balance: effects of DNA.
Biophysical journal 2001;81(4):2135-43.
2001: Arimatti Jutila; Tim Söderlund; Antti L Pakkanen; MO Huttunen; Paavo K J Kinnunen
Comparison of the effects of clozapine, chlorpromazine, and haloperidol on membrane lateral heterogeneity.
Chemistry and physics of lipids 2001;112(2):151-63.
2001: Keng Zhu; Arimatti Jutila; Esa K J Tuominen; Shamkant A Patkar; Allan Svendsen; Paavo K J Kinnunen
Impact of the tryptophan residues of Humicola lanuginosa lipase on its thermal stability.
Biochimica et biophysica acta 2001;1547(2):329-38.
2001: Esa K J Tuominen; Keng Zhu; Carmichael J A Wallace; I Clark-Lewis; D B Craig; M Rytomaa; Paavo K J Kinnunen
ATP induces a conformational change in lipid-bound cytochrome c.
The Journal of biological chemistry 2001;276(22):19356-62.
2001: Oula Penate Medina; Tim Söderlund; Liisa Laakkonen; Esa K J Tuominen; Erkki Koivunen; Paavo K J Kinnunen
Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro.
Cancer research 2001;61(10):3978-85.
2001: Susanne K Wiedmer; Jari T Hautala; Juha M Holopainen; Paavo K J Kinnunen; Marja-Liisa Riekkola
Study on liposomes by capillary electrophoresis.
Electrophoresis 2001;22(7):1305-13.
2001: Keng Zhu; Arimatti Jutila; Esa K J Tuominen; Paavo K J Kinnunen
Effects of i-propanol on the structural dynamics of Thermomyces lanuginosa lipase revealed by tryptophan fluorescence.
Protein science : a publication of the Protein Society 2001;10(2):339-51.
2001: Juha M Holopainen; H L Brockman; Rhoderick Brown; Paavo K J Kinnunen
Interfacial interactions of ceramide with dimyristoylphosphatidylcholine: impact of the N-acyl chain.
Biophysical journal 2001;80(2):765-75.
2001: J I Alakoskela; Paavo K J Kinnunen
Control of a redox reaction on lipid bilayer surfaces by membrane dipole potential.
Biophysical journal 2001;80(1):294-304.
2000: Juha M Holopainen; Matti J Säily; Javier Caldentey; Paavo K J Kinnunen
The assembly factor P17 from bacteriophage PRD1 interacts with positively charged lipid membranes.
European journal of biochemistry / FEBS 2000;267(20):6231-8.
2000: Susanne K Wiedmer; Juha M Holopainen; Pia Mustakangas; Paavo K J Kinnunen; Marja-Liisa Riekkola
Liposomes as carriers in electrokinetic capillary chromatography.
Electrophoresis 2000;21(15):3191-8.
2000: Juha M Holopainen; Oula Penate Medina; Antti J Metso; Paavo K J Kinnunen
Sphingomyelinase activity associated with human plasma low density lipoprotein.
The Journal of biological chemistry 2000;275(22):16484-9.
2000: M Subramanian; Juha M Holopainen; Tommi Paukku; Ove Eriksson; Ilpo Huhtaniemi; Paavo K J Kinnunen
Characterisation of three novel cationic lipids as liposomal complexes with DNA.
Biochimica et biophysica acta 2000;1466(1-2):289-305.
2000: Juha M Holopainen; J Lemmich; F Richter; Ole G Mouritsen; G Rapp; Paavo K J Kinnunen
Dimyristoylphosphatidylcholine/C16:0-ceramide binary liposomes studied by differential scanning calorimetry and wide- and small-angle x-ray scattering.
Biophysical journal 2000;78(5):2459-69.
2000: Keng Zhu; Arimatti Jutila; Paavo K J Kinnunen
Steady state and time resolved effects of guanidine hydrochloride on the structure of Humicola lanuginosa lipase revealed by fluorescence spectroscopy.
Protein science : a publication of the Protein Society 2000;9(3):598-609.
2000: Arimatti Jutila; Keng Zhu; Shamkant A Patkar; Jesper Vind; Allan Svendsen; Paavo K J Kinnunen
Detergent-induced conformational changes of Humicola lanuginosa lipase studied by fluorescence spectroscopy.
Biophysical journal 2000;78(3):1634-42.
2000: Juha M Holopainen; Miglena I Angelova; Paavo K J Kinnunen
Vectorial budding of vesicles by asymmetrical enzymatic formation of ceramide in giant liposomes.
Biophysical journal 2000;78(2):830-8.
1999: Esa K J Tuominen; Juha M Holopainen; J Chen; G D Prestwich; P R Bachiller; Paavo K J Kinnunen; P A Janmey
Fluorescent phosphoinositide derivatives reveal specific binding of gelsolin and other actin regulatory proteins to mixed lipid bilayers.
European journal of biochemistry / FEBS 1999;263(1):85-92.
1999: Juha M Holopainen; JY Lehtonen; Paavo K J Kinnunen
Evidence for the extended phospholipid conformation in membrane fusion and hemifusion.
Biophysical journal 1999;76(4):2111-20.
1999: Javier Caldentey; Anna-Liisa Hänninen; Juha M Holopainen; Jaana K H Bamford; Paavo K J Kinnunen; Dennis H Bamford
Purification and characterization of the assembly factor P17 of the lipid-containing bacteriophage PRD1.
European journal of biochemistry / FEBS 1999;260(2):549-58.
1999: Tim Söderlund; Arimatti Jutila; Paavo K J Kinnunen
Binding of adriamycin to liposomes as a probe for membrane lateral organization.
Biophysical journal 1999;76(2):896-907.
1999: Tim Söderlund; JY Lehtonen; Paavo K J Kinnunen
Interactions of cyclosporin A with phospholipid membranes: effect of cholesterol.
Molecular pharmacology 1999;55(1):32-8.
1998: Juha M Holopainen; M Subramanian; Paavo K J Kinnunen
Sphingomyelinase induces lipid microdomain formation in a fluid phosphatidylcholine/sphingomyelin membrane.
Biochemistry 1998;37(50):17562-70.
1998: Arimatti Jutila; M Rytömaa; Paavo K J Kinnunen
Detachment of cytochrome c by cationic drugs from membranes containing acidic phospholipids: comparison of lidocaine, propranolol, and gentamycin.
Molecular pharmacology 1998;54(4):722-32.
1998: Günther H Peters; Allan Svendsen; Henning Langberg; Jesper Vind; Shamkant A Patkar; S Toxvaerd; Paavo K J Kinnunen
Active serine involved in the stabilization of the active site loop in the Humicola lanuginosa lipase.
Biochemistry 1998;37(36):12375-83.
1998: P Mustonen; JY Lehtonen; Paavo K J Kinnunen
Binding of quinacrine to acidic phospholipids and pancreatic phospholipase A2. Effects on the catalytic activity of the enzyme.
Biochemistry 1998;37(35):12051-7.
1998: S Lauraeus; Juha M Holopainen; M R Taskinen; Paavo K J Kinnunen
Aggregation of dimyristoylphosphatidylglycerol liposomes by human plasma low density lipoprotein.
Biochimica et biophysica acta 1998;1373(1):147-62.
1998: M Subramanian; Arimatti Jutila; Paavo K J Kinnunen
Binding and dissociation of cytochrome c to and from membranes containing acidic phospholipids.
Biochemistry 1998;37(5):1394-402.
1997: Esa K J Tuominen; Carmichael J A Wallace; Paavo K J Kinnunen
The invariant ARG91 is required for the rupture of liposomes by cytochrome C.
Biochemical and biophysical research communications 1997;238(1):140-2.
1997: Juha M Holopainen; JY Lehtonen; Paavo K J Kinnunen
Lipid microdomains in dimyristoylphosphatidylcholine-ceramide liposomes.
Chemistry and physics of lipids 1997;88(1):1-13.
1997: Tommi Paukku; S Lauraeus; Ilpo Huhtaniemi; Paavo K J Kinnunen
Novel cationic liposomes for DNA-transfection with high efficiency and low toxicity.
Chemistry and physics of lipids 1997;87(1):23-9.
1997: JY Lehtonen; Paavo K J Kinnunen
Evidence for phospholipid microdomain formation in liquid crystalline liposomes reconstituted with Escherichia coli lactose permease.
Biophysical journal 1997;72(3):1247-57.
1996: JY Lehtonen; Herman Adlercreutz; Paavo K J Kinnunen
Binding of daidzein to liposomes.
Biochimica et biophysica acta 1996;1285(1):91-100.
1996: Olof P Karlsson; M Rytömaa; A Dahlqvist; Paavo K J Kinnunen; Ake Wieslander
Correlation between bilayer lipid dynamics and activity of the diglucosyldiacylglycerol synthase from Acholeplasma laidlawii membranes.
Biochemistry 1996;35(31):10094-102.
1996: JY Lehtonen; Juha M Holopainen; Paavo K J Kinnunen
Activation of phospholipase A2 by amyloid beta-peptides in vitro.
Biochemistry 1996;35(29):9407-14.
1996: JY Lehtonen; M Rytömaa; Paavo K J Kinnunen
Characteristics of the binding of tacrine to acidic phospholipids.
Biophysical journal 1996;70(5):2185-2194.
1996: M Rytömaa; Paavo K J Kinnunen
Dissociation of cytochrome c from liposomes by histone H1. Comparison with basic peptides.
Biochemistry 1996;35(14):4529-39.
1996: JY Lehtonen; Juha M Holopainen; Paavo K J Kinnunen
Evidence for the formation of microdomains in liquid crystalline large unilamellar vesicles caused by hydrophobic mismatch of the constituent phospholipids.
Biophysical journal 1996;70(4):1753-60.
1995: A Kõiv; J Palvimo; Paavo K J Kinnunen
Evidence for ternary complex formation by histone H1, DNA, and liposomes.
Biochemistry 1995;34(25):8018-27.
1995: JY Lehtonen; Paavo K J Kinnunen
Phospholipase A2 as a mechanosensor.
Biophysical journal 1995;68(5):1888-94.
1995: M Rytömaa; Paavo K J Kinnunen
Reversibility of the binding of cytochrome c to liposomes. Implications for lipid-protein interactions.
The Journal of biological chemistry 1995;270(7):3197-202.
1995: JY Lehtonen; Paavo K J Kinnunen
Poly(ethylene glycol)-induced and temperature-dependent phase separation in fluid binary phospholipid membranes.
Biophysical journal 1995;68(2):525-35.
1994: Paavo K J Kinnunen; A Kõiv; JY Lehtonen; M Rytömaa; P Mustonen
Lipid dynamics and peripheral interactions of proteins with membrane surfaces.
Chemistry and physics of lipids 1994;73(1-2):181-207.
1994: A Kõiv; Paavo K J Kinnunen
Binding of DNA to liposomes containing different derivatives of sphingosine.
Chemistry and physics of lipids 1994;72(1):77-86.
1994: JY Lehtonen; Paavo K J Kinnunen
Changes in the lipid dynamics of liposomal membranes induced by poly(ethylene glycol): free volume alterations revealed by inter- and intramolecular excimer-forming phospholipid analogs.
Biophysical journal 1994;66(6):1981-90.
1994: A Kõiv; P Mustonen; Paavo K J Kinnunen
Differential scanning calorimetry study on the binding of nucleic acids to dimyristoylphosphatidylcholine-sphingosine liposomes.
Chemistry and physics of lipids 1994;70(1):1-10.
1994: M Rytömaa; Paavo K J Kinnunen
Evidence for two distinct acidic phospholipid-binding sites in cytochrome c.
The Journal of biological chemistry 1994;269(3):1770-4.
1993: A Kõiv; P Mustonen; Paavo K J Kinnunen
Influence of sphingosine on the thermal phase behaviour of neutral and acidic phospholipid liposomes.
Chemistry and physics of lipids 1993;66(1-2):123-34.
1993: Paavo K J Kinnunen; M Rytömaa; A Kõiv; JY Lehtonen; P Mustonen; A Aro
Sphingosine-mediated membrane association of DNA and its reversal by phosphatidic acid.
Chemistry and physics of lipids 1993;66(1-2):75-85.
1993: P Mustonen; JY Lehtonen; A Kõiv; Paavo K J Kinnunen
Effects of sphingosine on peripheral membrane interactions: comparison of adriamycin, cytochrome c, and phospholipase A2.
Biochemistry 1993;32(20):5373-80.
1993: P Mustonen; Paavo K J Kinnunen
On the reversal by deoxyribonucleic acid of the binding of adriamycin to cardiolipin-containing liposomes.
The Journal of biological chemistry 1993;268(2):1074-80.
1992: Paavo K J Kinnunen
Fusion of lipid bilayers: a model involving mechanistic connection to HII phase forming lipids.
Chemistry and physics of lipids 1992;63(3):251-8.
1992: M Rytömaa; P Mustonen; Paavo K J Kinnunen
Reversible, nonionic, and pH-dependent association of cytochrome c with cardiolipin-phosphatidylcholine liposomes.
The Journal of biological chemistry 1992;267(31):22243-8.
1992: A Kõiv; Paavo K J Kinnunen
Influence of Ca2+ and ethanol on the aggregation and thermal phase behaviour of L-dihexadecylphosphatidylcholine liposomes.
Chemistry and physics of lipids 1992;62(3):253-61.
1992: Kari K Eklund; J A Virtanen; Paavo K J Kinnunen; J Kasurinen; Pentti Somerharju
Conformation of phosphatidylcholine in neat and cholesterol-containing liquid-crystalline bilayers. Application of a novel method.
Biochemistry 1992;31(36):8560-5.
1992: P Mustonen; Paavo K J Kinnunen
Substrate level modulation of the activity of phospholipase A2 in vitro by 12-O-tetradecanoylphorbol-13-acetate.
Biochemical and biophysical research communications 1992;185(1):185-90.
1991: Pertti Kaihovaara; Erkki Raulo; Paavo K J Kinnunen
Changes in lipid distribution and dynamics in degranulated rat liver rough endoplasmic reticulum due to the membrane attachment of polyribosomes.
Biochemistry 1991;30(34):8380-6.
1991: T Thuren; Paavo K J Kinnunen
A continuous fluorometric assay for phospholipase C from Clostridium perfringens.
Chemistry and physics of lipids 1991;59(1):69-74.
1991: Kari K Eklund; P Vainio; J A Virtanen; Paavo K J Kinnunen
Esterase activity of synthetic fragments of human adrenocorticotrophic hormone.
Biochemical and biophysical research communications 1991;177(1):235-42.
1991: P Mustonen; Paavo K J Kinnunen
Activation of phospholipase A2 by adriamycin in vitro. Role of drug-lipid interactions.
The Journal of biological chemistry 1991;266(10):6302-7.
1991: Paavo K J Kinnunen
On the principles of functional ordering in biological membranes.
Chemistry and physics of lipids 1991;57(2-3):375-99.
1991: Kari K Eklund; J E Takkunen; Paavo K J Kinnunen
Cation-induced aggregation of acidic phospholipid vesicles: the role of fatty acid unsaturation and cholesterol.
Chemistry and physics of lipids 1991;57(1):59-66.
1990: Wagner F Gattaz; C V Hübner; T J Nevalainen; T Thuren; Paavo K J Kinnunen
Increased serum phospholipase A2 activity in schizophrenia: a replication study.
Biological psychiatry 1990;28(6):495-501.
1990: T Thuren; Kari K Eklund; J A Virtanen; Paavo K J Kinnunen
Hydrolysis of supported pyrenephospholipid monolayers by phospholipase A2.
Chemistry and physics of lipids 1990;55(1):55-60.
1990: T I Lotta; A P Tulkki; J A Virtanen; Paavo K J Kinnunen
Interaction of 7,7,8,8-tetracyanoquinodimethane with diacylphosphatidylcholines and -phosphatidylglycerols. A photoacoustic Fourier transform infrared study.
Chemistry and physics of lipids 1990;52(1):11-27.
1989: I S Salonen; Kari K Eklund; J A Virtanen; Paavo K J Kinnunen
Comparison of the effects of NaCl on the thermotropic behaviour of sn-1' and sn-3' stereoisomers of 1,2-dimyristoyl-sn-glycero-3-phosphatidylglycerol.
Biochimica et biophysica acta 1989;982(2):205-15.
1988: T I Lotta; I S Salonen; J A Virtanen; Kari K Eklund; Paavo K J Kinnunen
Fourier transform infrared study of fully hydrated dimyristoylphosphatidylglycerol. Effects of Na+ on the sn-1' and sn-3' headgroup stereoisomers.
Biochemistry 1988;27(21):8158-69.
1988: Kari K Eklund; J Vuorinen; J Mikkola; J A Virtanen; Paavo K J Kinnunen
Ca2+-induced lateral phase separation in phosphatidic acid/phosphatidylcholine monolayers as revealed by fluorescence microscopy.
Biochemistry 1988;27(9):3433-7.
1988: T Thuren; J A Virtanen; Pentti Somerharju; Paavo K J Kinnunen
Phospholipase A2 assay using an intramolecularly quenched pyrene-labeled phospholipid analog as a substrate.
Analytical biochemistry 1988;170(1):248-55.
1988: T I Lotta; J A Virtanen; Paavo K J Kinnunen
Fourier transform infrared study on the thermotropic behaviour of fully hydrated 1-palmitoyl-2-[10-(pyren-1-y) decanoyl]-sn-glycero-3-phosphatidylcholine.
Chemistry and physics of lipids 1988;46(1):13-23.
1988: T I Lotta; L J Laakkonen; J A Virtanen; Paavo K J Kinnunen
Characterization of Langmuir-Blodgett films of 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine and 1-palmitoyl-2-[10-(pyren-1-yl)decanoyl]-sn-glycero-3-phosphat idylcholine by FTIR-ATR.
Chemistry and physics of lipids 1988;46(1):1-12.
1987: Kari K Eklund; J A Virtanen; K Vuori; J Patrikainen; Paavo K J Kinnunen
Role of the polar head group stereoconfiguration in the cation-induced aggregation of dimyristoylphosphatidylglycerol vesicles.
Biochemistry 1987;26(24):7542-5.
1987: T Thuren; J A Virtanen; Paavo K J Kinnunen
Control of the action of phospholipases A by "vertical compression" of the substrate monolayer.
Biochemistry 1987;26(18):5816-9.
1987: T Thuren; A P Tulkki; J A Virtanen; Paavo K J Kinnunen
Triggering of the activity of phospholipase A2 by an electric field.
Biochemistry 1987;26(16):4907-10.
1987: P Mustonen; J A Virtanen; Pentti Somerharju; Paavo K J Kinnunen
Binding of cytochrome c to liposomes as revealed by the quenching of fluorescence from pyrene-labeled phospholipids.
Biochemistry 1987;26(11):2991-7.
1987: Wagner F Gattaz; M Köllisch; T Thuren; J A Virtanen; Paavo K J Kinnunen
Increased plasma phospholipase-A2 activity in schizophrenic patients: reduction after neuroleptic therapy.
Biological psychiatry 1987;22(4):421-6.
1987: T Thuren; J A Virtanen; R Verger; Paavo K J Kinnunen
Hydrolysis of 1-palmitoyl-2-[6-(pyren-1-yl)]hexanoyl-sn-glycero- 3-phospholipids by phospholipase A2: effect of the polar head-group.
Biochimica et biophysica acta 1987;917(3):411-7.
1986: T Thuren; J A Virtanen; Paavo K J Kinnunen
Estimation of the equilibrium lateral pressure in 1-palmitoyl-2-[6(pyren-1-yl)]hexanoyl-glycerophospholipid liposomes.
Chemistry and physics of lipids 1986;41(3-4):329-34.
1986: T Thuren; J A Virtanen; Paavo K J Kinnunen
Polyamine-phospholipid interaction probed by the accessibility of the phospholipid sn-2 ester bond to the action of phospholipase A2.
The Journal of membrane biology 1986;92(1):1-7.
1985: Pentti Somerharju; J A Virtanen; Kari K Eklund; P Vainio; Paavo K J Kinnunen
1-Palmitoyl-2-pyrenedecanoyl glycerophospholipids as membrane probes: evidence for regular distribution in liquid-crystalline phosphatidylcholine bilayers.
Biochemistry 1985;24(11):2773-81.
1985: T Thuren; J A Virtanen; M Lalla; Paavo K J Kinnunen
Fluorometric assay for phospholipase A2 in serum.
Clinical chemistry 1985;31(5):714-7.